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2026

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Exploring The Postpartum Recovery After Hyperemesis Gravidarum: A Qualitative Study, Zeinab El-Dirani, Sergio A. Silverio, Eleni Niarchou, Elana Payne, Pauline Dunne, Melanie Nana, Catherine Williamson, Mary F. Higgins, Eileen O'Brien, Joan Devin, Aisling Walsh, Angela C. Flynn Jan 2026

Exploring The Postpartum Recovery After Hyperemesis Gravidarum: A Qualitative Study, Zeinab El-Dirani, Sergio A. Silverio, Eleni Niarchou, Elana Payne, Pauline Dunne, Melanie Nana, Catherine Williamson, Mary F. Higgins, Eileen O'Brien, Joan Devin, Aisling Walsh, Angela C. Flynn

Research Outputs: 2025-Present

Introduction: Hyperemesis Gravidarum affects 0.3–3.6% of women during pregnancy and has a significant impact on maternal health. Investigation of both the immediate and longer-term effects remains a high research priority. However, there is limited research on postpartum recovery after hyperemesis gravidarum. Aim: To explore the postpartum recovery experiences of women who had hyperemesis gravidarum. Methods: A large descriptive qualitative study was conducted using semi-structured interviews to explore the postpartum experiences of women who had hyperemesis gravidarum within the previous 5 years in Ireland. Data were analysed using reflexive thematic analysis. Results: Forty-one women participated, and four themes were identified: (1) …


Myopiax-1 Safety And Efficacy Of A Novel Approach To Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial, Myopiax-1 Study Group, James Loughman, Gareth Lingham, Hakan Kaymak, Katrin Lorenz, Jan Roelof Polling, Anna Beck, Gonzalo Carracedo, Annegret H. Dahlmann-Noor, Philipp L. Müller, Ian Flitcroft Jan 2026

Myopiax-1 Safety And Efficacy Of A Novel Approach To Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial, Myopiax-1 Study Group, James Loughman, Gareth Lingham, Hakan Kaymak, Katrin Lorenz, Jan Roelof Polling, Anna Beck, Gonzalo Carracedo, Annegret H. Dahlmann-Noor, Philipp L. Müller, Ian Flitcroft

Research Outputs: 2025-Present

Purpose: To investigate the safety, tolerability, and signals of effect of MyopiaX, a smartphone app that selectively delivers blue light to the optic nerve head to control myopia progression in children and adolescents. Design: Multicenter, randomized, active-controlled, examiner-masked proof-of-concept clinical trial (ClinicalTrials.gov identifier NCT04967287). Participants: Eligible children aged 6 to 12 years, with myopia of cycloplegic spherical equivalent refraction (SER) between –0.75 and –5.00 diopters (D) at baseline. Children were screened and enrolled between November 2021 and September 2023. Methods: Children were randomly assigned in a 2:1 ratio to MyopiaX or active control. Participants were instructed to use MyopiaX for …


Readability Of Online Patient Education Materials For Myopia Management, Monica Jong, Michelle Waugh, Pinar Ozmizrak, Ian Flitcroft Jan 2026

Readability Of Online Patient Education Materials For Myopia Management, Monica Jong, Michelle Waugh, Pinar Ozmizrak, Ian Flitcroft

Research Outputs: 2025-Present

Purpose: Patients are turning to the internet to access educational materials to help them make healthcare decisions, making readability an important factor. This cross-sectional study assessed the readability of online patient education materials for myopia management treatments that have regulatory approval. Methods: The top 10 Google search results from May 2024 for freely available online patient information on myopia management modalities and regulatory-approved products in Canada and Australia were analysed for readability. The modalities included orthokeratology, myopia control spectacle lenses, myopia control soft contact lenses and atropine. The products included MiYOSMART® [HOYA®], Stellest® [Essilor®], MyoCare® [ZEISS], MiSight® 1 day [CooperVision®], …


Are Ocular Markers Of Sun Exposure Associated With Skin Cancer? A Cross-Sectional Analysis Of The Busselton Healthy Ageing Study, Gareth Lingham, Vinay Kumar Nilagiri, Holly Brown, Chrianna Bharat, Samantha S.Y. Lee, Maria Franchina, Michael Hunter, Kevin Murray, David Alonso-Caneiro, Catherine M. Olsen, David C. Whiteman, David A. Mackey Jan 2026

Are Ocular Markers Of Sun Exposure Associated With Skin Cancer? A Cross-Sectional Analysis Of The Busselton Healthy Ageing Study, Gareth Lingham, Vinay Kumar Nilagiri, Holly Brown, Chrianna Bharat, Samantha S.Y. Lee, Maria Franchina, Michael Hunter, Kevin Murray, David Alonso-Caneiro, Catherine M. Olsen, David C. Whiteman, David A. Mackey

Research Outputs: 2025-Present

Background: Higher past sun or ultraviolet radiation exposure increases the risk of skin cancer and three common ocular findings: pterygium, conjunctival ultraviolet autofluorescence (CUVAF) and myopia. We investigated whether ocular markers of past sun exposure are associated with a history of skin cancer. Methods: A cross-sectional study of participants who attended the Phase 2 examination of the Busselton Healthy Ageing Study in Western Australia (2016–2022). Myopia was determined from autorefraction and pterygium and CUVAF from photographs of the anterior eye. Past diagnosis of a skin cancer was obtained from linked hospitalisation and cancer registry data (melanoma) or combining linked and …


Exploring Characteristics And Systemic Health Links In Myopic Australian Adults, Pauline Kang, Gareth Lingham, Angelica Ly, Xianwen Shang, Regan Ashby, Serge Resnikoff, Fiona Stapleton, David Mackey Jan 2026

Exploring Characteristics And Systemic Health Links In Myopic Australian Adults, Pauline Kang, Gareth Lingham, Angelica Ly, Xianwen Shang, Regan Ashby, Serge Resnikoff, Fiona Stapleton, David Mackey

Research Outputs: 2025-Present

Background: Data on myopia prevalence in Australia and associations with common systemic conditions and quality of life are limited. This study aimed to profile Australian adults self-reporting to have myopia, including co-morbidities and quality of life. Methods: This research included participants from the ongoing longitudinal 45 and Up Study. Sex and education data were collected at the baseline survey and additional data from the follow-up Health Compass survey. Responses on self-reported myopia, health and quality of life were analysed with logistic regression to assess the association between myopia and health conditions. Results: Of the 21,384 participant responses, 54.3% self-reported myopia, …


Impact Of Protein Corona Morphology On Nanoparticle Diffusion In Biological Fluids: Insights From A Mesoscale Approach, Beatrice Cipriani, Hender Lopez Jan 2026

Impact Of Protein Corona Morphology On Nanoparticle Diffusion In Biological Fluids: Insights From A Mesoscale Approach, Beatrice Cipriani, Hender Lopez

Research Outputs: 2025-Present

Nanoparticles (NPs) demonstrate considerable potential in medical applications, including targeted drug delivery and diagnostic probes. However, their efficacy depends on their ability to navigate through the complex biological environments inside living organisms. In such environments, NPs interact with a dense mixture of biomolecules, which can reduce their mobility and hinder diffusion. Understanding the factors influencing NP diffusion in these environments is key to improving nanomedicine design and predicting toxicological effects. In this study, we propose a computational approach to model NP diffusion in crowded environments. We introduce a mesoscale model that accounts for the combined effects of the protein corona …


Modeling The Impact Of Proton Irradiation On Photoluminescence Spectra Of Perovskite Solar Cells, Ming Lang Tseng, Nima Ghadiri Jan 2026

Modeling The Impact Of Proton Irradiation On Photoluminescence Spectra Of Perovskite Solar Cells, Ming Lang Tseng, Nima Ghadiri

Research Outputs: 2025-Present

This study presents a comprehensive modeling approach to assess the impact of proton-irradiation on the photoluminescence (PL) response and current–voltage (JV) characteristics of CsMAFAPbI3/P3HT-based perovskite solar cell validated against experimental data reported in literature. Proton irradiation generates displacement damage across the cell structure most critically within the perovskite bulk where the defect density increases approximately linearly with increased fluence and decreases for high proton energies due to reduced non-ionizing energy loss (NIEL) at higher energies. To capture the optical degradation behavior, Time-Resolved PL transient (TRPL) and PL spectra were modeled using a fluence- and energy-dependent Kohlrausch model (stretched-exponential) …


Ocular Dominance Is Associated With Interocular Asymmetry In Refractive Error And Axial Length Across Childhood And Early Adulthood, Síofra C. Harrington, Gareth Lingham, James Loughman, Ian Flitcroft, David A. Mackey, Michael Moore Jan 2026

Ocular Dominance Is Associated With Interocular Asymmetry In Refractive Error And Axial Length Across Childhood And Early Adulthood, Síofra C. Harrington, Gareth Lingham, James Loughman, Ian Flitcroft, David A. Mackey, Michael Moore

Research Outputs: 2025-Present

Purpose: To determine whether ocular dominance is associated with systematic interocular asymmetry in spherical equivalent refraction (SER) and axial length (AL) across childhood and early adulthood, and assess whether such asymmetry exceeds laterality effects. Methods: Data were analysed from three population-based cohorts: 728 children (6–7-year-olds) and 898 adolescents (12–13-year-olds) from Ireland and 303 young adults (25–30-year-olds) from Western Australia. Ocular dominance was assessed using sighting tests. SER was measured by cycloplegic autorefraction and AL by optical biometry. Interocular differences were evaluated using paired comparisons, concordance correlation coefficients (CCC), Deming regression, Bland–Altman analyses and mediation modelling. Analyses were stratified by refractive …


Axial Length To Corneal Curvature Ratio Is Insufficient For Detecting Pseudomyopia In Children: A Multi-Cohort Study, The Cream-Kids Consortium, Huyen T. Bui, Dirk J. Van Hemert, Tianli Peng, Shuhui Yang, Hai Yen T. Nguyen, Hannah Noor, Siofra C. Harrington, Sander C.M. Kneepkens, Lene A. Hagen, Craig S. Walker, Edward Mallen, Matthew Cufflin, Rigmor C. Baraas, Neema Ghorbani-Mojarrad, Olavi Pärssinen, Louise Terry, Shi Ming Li, Amanda N. French, Jason C. Yam, Caroline C.W. Klaver, Jeremy A. Guggenheim Jan 2026

Axial Length To Corneal Curvature Ratio Is Insufficient For Detecting Pseudomyopia In Children: A Multi-Cohort Study, The Cream-Kids Consortium, Huyen T. Bui, Dirk J. Van Hemert, Tianli Peng, Shuhui Yang, Hai Yen T. Nguyen, Hannah Noor, Siofra C. Harrington, Sander C.M. Kneepkens, Lene A. Hagen, Craig S. Walker, Edward Mallen, Matthew Cufflin, Rigmor C. Baraas, Neema Ghorbani-Mojarrad, Olavi Pärssinen, Louise Terry, Shi Ming Li, Amanda N. French, Jason C. Yam, Caroline C.W. Klaver, Jeremy A. Guggenheim

Research Outputs: 2025-Present

Purpose: Pseudomyopia is an accommodative disorder that can be identified by the difference between pre- and post-cycloplegic refractive error. The current study aimed to evaluate whether the axial length to corneal curvature (AL/CR) ratio, in conjunction with non-cycloplegic refractive error, can reliably identify pseudomyopia in children, thus avoiding the need for cycloplegia. Methods: Refractive error and biometry data from longitudinal studies based in Denmark (n = 645; age 7–17 years) and China (Anyang Childhood Eye Study; n = 2487; age 6–13 years) were used to train separate linear mixed models for children of European or East Asian ancestry, respectively, with …


Regulatory Invisibility And Energy Poverty: Epc Exclusion, Traveller Mobile Homes And Ireland’S Low-Carbon Transition, Paul Lally, Ehiaze Ehimen, Mary Galvin, Ciara Ahern Jan 2026

Regulatory Invisibility And Energy Poverty: Epc Exclusion, Traveller Mobile Homes And Ireland’S Low-Carbon Transition, Paul Lally, Ehiaze Ehimen, Mary Galvin, Ciara Ahern

Research Outputs: 2025-Present

Energy Performance Certificate (EPC) systems play a central role in residential decarbonisation by determining how dwellings are assessed, benchmarked and made eligible for retrofit support. However, these systems are largely designed around conventional, permanent, site-built housing and can exclude non-standard dwelling types. This paper examines the exclusion of permanently occupied Traveller mobile homes from Ireland’s EPC framework and considers the implications for energy poverty, retrofit policy and energy justice. Using a critical narrative synthesis, the study integrates academic literature, statutory reports, policy documents and community-based evidence to trace the relationship between Traveller accommodation policy, regulatory classification and contemporary decarbonisation frameworks. …