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Does Subarachnoid Dexmedetomidine Decrease The Incidence Of Shivering And Postoperative Nausea And Vomiting In Cesarean Section?A Prospective Randomized Controlled Trial, Ali El-Sayed Khayal, Amr Abdellatif

Journal of Medicine in Scientific Research

Background: Spinal anesthesia during cesarean sections is associated with a number of common problems, including postoperative nausea and vomiting (PONV), which can make the mother feel uneasy and negatively impact the perioperative results. The neuraxial adjuvant dexmedetomidine has shown promise since it is a very selective α₂- adrenergic receptor agonist that can improve spinal anesthesia and also provide extra sedative and anti-shivering effects. Objective:To evaluate the effect of adding 5μg intrathecal dexmedetomidine to hyperbaric bupivacaine on the incidence of shivering and PONV during elective cesarean section. Patients and Methods: Elective caesarean sections under spinal anesthesia were elective for 100 healthy …

Efficacy And Safety Of General Anaesthesia Versus Local Anaesthesia With Iv Sedation In Transcatheter Aortic Valve Implantation (Tavi), Reham Salah, Ahmed Kamel Abdelghany Hassan, Sherif Ahmed Kamal Elhendawy

Journal of Medicine in Scientific Research

The optimal anesthetic approach for transcatheter aortic valve implantation (TAVI) remains a subject of ongoing debate. Although general anesthesia (GA) allows greater procedural control and airway security, local anesthesia with conscious sedation (LACS) may facilitate faster postoperative recovery and reduce procedure-related complications. This study aimed to compare the efficacy and safety of GA versus CS in patients undergoing transfemoral TAVI.

Comparison Between Central Corneal Thickness Measured By Anterior Segment Optical Coherence Tomography And Pentacam, Osama Ramadan Mahmoud, Rabab El Araby Lawash, Hanan Mohamed Abdel Hamid Ahmed

Journal of Medicine in Scientific Research

Background: Central corneal thickness (CCT) is crucial in ophthalmic practice helping diagnosis and management of various conditions such as glaucoma, keratoconus, corneal dystrophy, contact lens use and proceeding refractive procedures assessment. A lot of non-contact modalities are currently available for CCT evaluation including anterior segment optical coherence tomography (AS-OCT) and the Pentacam systems so we are in need of determining the degree of agreement between these instruments to establish an accurate clinical interpretation. Aim: To test correlation between corneal thickness measurements obtained using Pentacam and AS-OCT. Patients and Methods: Our comparative observational study included 50 eyes. CCT was measured in …

Incidental Extracardiac Findings In Cardaic Mr Imaging, Shaimaa S Mohamed, Elhardalo O Mohamed, Mohamed A Ali, Shimaa S Attia

Journal of Medicine in Scientific Research

Background: Cardiac magnetic resonance imaging (cMRI) is recently a pivotal noninvasive technique for comprehensive cardiac assessment, providing detailed cardiac anatomy and motility insights. Given its expansive field of view, cMRI facilitates the identification of incidental extracardiac findings (IEFs), that may have clinical significance beyond the primary cardiac evaluation.

Objective: This study aims to assess the prevalence of incidental extracardiac findings noted in cMRI and to address the most frequent detected lesions.

Methods: A retrospective study was conducted on patients who have done cMRI in the period between July 2021 and July 2023. The study cohort consisted of 219 individuals referred …

Heart-Type Fatty Acid Binding Protein In Early Diagnosis Of Acute Myocardial Infarction, Reem Safwat Mohamad, Asmaa Younis Elsary, Mohamed M. Elbably

Journal of Medicine in Scientific Research

Background: Timely identification of acute myocardial infarction (AMI) plays a vital role in ensuring prompt treatment and better clinical outcomes. Traditional cardiac indicators involving creatine kinase-myocardial band (CK-MB) and cardiac troponin I (cTnI) demonstrate reduced diagnostic accuracy through the initial hours after symptom presentation.

Aim: This research aimed to assess the diagnostic accuracy of heart-type fatty acid-binding protein (H-FABP) in comparison with cTnI, CK-MB, and lactate dehydrogenase (LDH) among cases presenting with acute chest pain, with particular focus on its role in early AMI detection.

Methods: A case-control investigation was conducted involving 60 AMI patients from the National Heart Institute …

Early Outcome Of Coronary Artery Bypass Grafting In 1,000 Egyptian Patients And Predictors Of Hospital Mortality, Ramdan Ibrahim Mohammed Ouf

Journal of Medicine in Scientific Research

Background Coronary artery bypass grafting (CABG) is a prevalent therapeutic intervention for the management of coronary artery disease. CABG significantly increases life expectancy. However, it is associated with peri-operative morbidity and mortality. Aim of the study to analyze the clinical and demographic attributes of patients undergoing isolated CABG and determine the early outcomes and the predictors of hospital mortality. Methods This is a retrospective observational study was conducted in National Heart Institute to describe the demographic and clinical characteristics of 1,000 Egyptian patients undergoing isolated CABG between January 2021 and January 2024. Results Our study included 1000 patients (mean age …

Comparison Of Suture Materials In Pfannensteil Incision Closure, Ali Elsayed Khayal, Ahmed Alsayed Kassab

Journal of Medicine in Scientific Research

Background: Surgeons worldwide perform C-sections more often than almost any other procedure, a trend that shows a steady and ongoing increase. Despite its safety profile, postoperative wound complications remain a significant source of maternal morbidity, prolonged hospitalization, and increased healthcare costs. Optimal skin closure technique following Pfannenstiel incision remains controversial, particularly regarding the choice between absorbable braided and non-absorbable monofilament sutures.

Objective: To compare wound morbidity and surgical outcomes following Pfannenstiel skin closure using polyglactin 910 (Vicryl) versus polypropylene (Prolene) in women undergoing cesarean delivery.

Methods: This prospective randomized controlled trial included 200 women undergoing elective or emergency cesarean section …

Patient Pathways And Outcomes Following Referral To A Dedicated Clinic For Tavi Program: Insights From The Egyptian National Heart Institute, Ramy Mohamed Omar, Ahmad Hassanen Gaber, Tarek M Abdel Aziz Elkholy

Journal of Medicine in Scientific Research

Background

The most common valvular heart disease in elderly populations and with a dismal prognosis in the case of its development is degenerative aortic stenosis. The use of transcatheter aortic valve implantation (TAVI) has transformed the treatment of the entire surgical risk spectrum, but there is limited real-world data that define the patterns of treatment and post-treatment results in the Middle East and North Africa (MENA) region.

Objectives

To characterize the pattern of treatment allocation, clinical and procedural outcome, and predictors at the baselines of six months mortality in patients in a row who were referred to a specialist assessment …

Comparison Of Dexmedetomidine And Ketamine Versus Propofol And Ketamine For Procedural Sedation In Children Undergoing Minor Cardiac Procedures In Cardiac Catheterization Laboratory, Reham Salah, Amr Ahmed Samir

Journal of Medicine in Scientific Research

Background: The optimal anesthetic approach for the care of pediatric patients facing cardiac catheterization stays undefined. Therefore, this study sought to equivalence the impact of ketamine-propofol and ketamine-dexmedetomidine mixtures on recovery duration and hemodynamic parameters in pediatric patients suffering trivial procedures and cardiac catheterization, while sedated for the treatment of numerous congenital heart diseases.

Materials and Method: One hundred twenty-six pediatric patients, irrespective of sex, scheduled for cardiac catheterization were arbitrarily billed to one of two groups: a propofol-ketamine group (PK) and a dexmedetomidine-ketamine group (DK), every comprising sixty-three patients. Group (DK) established Dexmedetomidine iv infusion 1µg/kg over ten min …

Association Between Red Cell Distribution Width And Type 2 Diabetes Mellitus, Walaa Saad Mohammed Ibrahim

Journal of Medicine in Scientific Research

Background:

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia and associated complications. Red cell distribution width (RDW), an index of the variability in red blood cell size, has emerged as a potential biomarker of inflammation and vascular risk.

Objective:

To assess the association between RDW and T2DM and its relation to glycemic control

Patients and Methods:

The current case-control study enrolled 40 T2DM patients and 20 age- and sex-matched healthy controls. Data collected included fasting blood sugar (FBS), 2-hour postprandial glucose (2hPP), HbA1c, lipid profile, albumin/creatinine ratio (ACR), and RDW. Statistical analysis included …

Role Of Complete Blood Cells Indices In Predicting Neonatal Sepsis Mortality, Sohaila Ali Abd El-Halim, Marwa Taha, Fifi Helmy Aboualy, Raghda Samir Abdellatif, Mai Mohammed Mostafa

Journal of Medicine in Scientific Research

Background: Neonatal sepsis remains a leading cause of morbidity and mortality in newborns. Identifying reliable prognostic markers is crucial for early diagnosis and treatment. Elevated levels of C-reactive protein (CRP) and increased platelet distribution width (PDW) have been associated with adverse outcomes in septic neonates. Objective: This study was performed in an attempt to assess the predictive value of Complete Blood Count (CBC) indices, including red cell distribution width (RDW), mean platelet volume (MPV), and PDW for mortality in septic neonates. Patients and Methods: This cohort study was conducted in the neonatal intensive care unit (NICU) of Mataria Teaching Hospital …

Identification Of The Seventh Cervical Vertebra By Palpation With Neck Rotation And Side Bending In Patients With Neck Pain., Eslam Elsayed Ali Shohda, Malaka Abdelmoniem Ibrahim El Khawaga, Amr Abdelaziz Hanafi Mohamed

Journal of Medicine in Scientific Research

Background: Precise localization of vertebral levels through clinical examination represents an essential competency for healthcare professionals across multiple disciplines. The present study sought to assess the reliability of identifying the seventh cervical vertebra (C7) via palpation during cervical rotation and side bending in individuals experiencing neck pain.

Materials and Methods: A cross-sectional study was carried out in the physiotherapy outpatient department of Al-Ahrar Teaching Hospital, located in Zagazig, Egypt. Thirty individuals with complaints of neck pain were recruited for participation. The seventh cervical vertebra (C7) was determined by palpating the most mobile vertebra among the three most prominent cervical segments …

The Role Of Evaluation Of Fetal Lung By Gray Scale & Doppler Us In Prediction Of Fetal Lung Maturity, Rana Elshennawy Nasr Ammar, Diaa Monir Ajlan, Mohammad Abdellatif Nassar, Shereef Lofty Elshwaikh

Journal of Medicine in Scientific Research

Background Neonatal respiratory distress syndrome (RDS) is a major cause of neonatal morbidity and mortality, especially in preterm infants. Traditional assessments of fetal lung maturity often require amniocentesis, an invasive procedure with significant risks. Noninvasive ultrasound-based methods could help optimize the timing of preterm delivery. Aim To determine whether the gray-scale echogenicity of the fetal lung and Doppler indices of the fetal main pulmonary artery (MPA) can predict fetal lung maturity and the risk of neonatal RDS in late preterm pregnancies. Patients & Methods A prospective cohort study was performed in the Obstetrics and Gynecology Department of Tanta University Hospitals …

Physiological, Cytogenetic, And Nutrition Effects Of Garcinia Cambogia And Ginkgo Biloba Aqueous Extracts On The Reproductive Functions Of Diabetic Male Rats, Marwa E. Hassan, Mahmoud M. Ahmed, Sherien A. Montaser, Sherein S. Abdelgayed, Asmaa M.I. El Gamal

Journal of Medicine in Scientific Research

Introduction

Diabetes disturbed humans from living normally, while Nature tries to help us again. Remarkable herbs biodiversity reflects a wide array of mechanisms.

Aim

Present study aims to track male annoying consequences of diabetic on fertility, trying to improve these hazards using two different herbs Garcinia cambogia and Ginkgo biloba.

Materials and methods

30 male Albino Sprague Dawely rats in six groups (5 rats each). Groups; 1^st group (negative control). 2^nd and 3^rd were treated orally with (200 mg/kg bw) for both G. cambogia and G. biloba. 4^th was +ve control (diabetic rat model) induced …

Prevalence Of Diabetic-Nephropathy In Children And Adolescents With Type-One- Diabetes Mellitus: A Recent Perspective, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Jehan Ibrahim Altohamy, Dina Mahmoud Khalifa

Journal of Medicine in Scientific Research

Background Among the most important microvascular complications in Type-one-Diabetes Mellitus (T-1-DM) in adolescents and children, Diabetic-nephropathy (DN) stands high. Early detection is crucial to prevent its progress to chronic kidney disease. Objective This study was designed aiming at the elaboration of an updated prevalence for Diabetic-nephropathy and to identify the risk factors among pediatric patients age group with T-1-DM . Methods The present cross-sectional-study was conducted starting from September 2023 to September 2025 including a group of 100 cases of adolescents and children with T-1- DM (aged 5–16 years) and 100-matched age and sex healthy control group. Clinical evaluation included …

Effectiveness Of Interferential Stimulation And Anorectal Neuromuscular Electrical Stimulation On Secondary Encopresis In Children: A Comparative Randomized Controlled Clinical Trial, Seham M. Abd El-Moghny, Mohamed I. Elsepaee, Abdelaty Alghonimy, Rabab S. Mohamed

Journal of Medicine in Scientific Research

Background Encopresis, fecal soiling is often secondary to functional constipation and retention. It is significantly impact a child's psychological health as it can result in feelings of shame, social isolation, and low self-esteem and negatively affect their quality of life and their families. Objective To evaluate and compare the efficacy and safety of interferential stimulation (IF) applied on sigmoid colon and anorectal neuromuscular electrical stimulation (NMES), in combination with behavioral therapy and pelvic floor muscle training (PFMT), in improving continence outcomes in children with secondary encopresis refractory to laxatives. Methods In this comparative randomized controlled clinical trial, 30 children (5–10 …