Digital Commons Network^™

Establishing Demographic-Based Normative Values For Neurofilament Light Chain And Glial Fibrillary Acidic Protein In Serum And Plasma Samples, Tyler L Borko, Salim Chahin, Et Al.

2020-Current year OA Pubs

BACKGROUND: Interpretation of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) levels in blood requires reference ranges from healthy cohorts, accounting for demographic features.

OBJECTIVE: To compare serum and plasma NfL and GFAP in healthy individuals, accounting for age, sex, and body mass index (BMI).

METHODS: Adolescents through older adults were recruited at Colorado community events and a senior clinic. A neurologist reviewed self-reported medical histories. Paired serum and EDTA plasma samples were assayed using the Quanterix SR-X Simoa Neuro 4-Plex. Log-linear models estimated percent change per year of age, per BMI unit, and sex ratios. GFAP used …

Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang

Research outputs 2022 to 2026

Purpose: This study emphasizes the growing significance of destination attributes in shaping the experiences and behaviours of gastronomy and culinary tourists. Understanding both core and complementary attributes of a gastronomy tourism destination is crucial for its sustainable development. However, there is a lack of a reliable measurement for tourists’ perceived attributes of gastronomy tourism destinations (PAGTD). Therefore, the purpose of this study is to develop a scale to measure tourists’ PAGTD. Design/methodology/approach: The study systematically followed the scale development and validation process, using three samples (Sample 1, n = 200; Sample 2, n = 204; and Sample 3, n = …

A Figurational Analysis Of Health And/Or Physical Education Teacher Educators’ Conceptualisations Of Policy, And Their Sociogenesis, Laura Alfrey, Dylan Scanlon, David Aldous, Jenna Lorusso, Kellie Baker, Christopher Clark, Mo Jafar

Research outputs 2022 to 2026

Policy engagement is key to promoting quality physical education yet it has been identified as a ‘grand challenge’ for Health and/or Physical Education (H/PE) internationally. All H/PE professionals, including teacher educators, have a collective responsibility to engage with policy but existing research tells us little about how H/PE teacher educators (H/PETEs) understand and engage with policy. It is important to examine H/PETEs conceptualisations of policy for a few reasons, not least because teacher educators play a crucial role in supporting future generations of teachers who themselves will need to engage with policy as a core feature of their professional lives. …

Determinants Of Artificial Intelligence Adoption: Research Themes And Future Directions, Ahmad A. Khanfar, Reza Kiani Mavi, Mohammad Iranmanesh, Denise Gengatharen

Research outputs 2022 to 2026

The adoption of artificial intelligence (AI) systems is on the rise owing to their many benefits. This study conducted a bibliometric analysis to identify (1) how the literature on AI adoption has evolved over the past few years, (2) key themes associated with AI adoption in the literature, and (3) the gaps in the literature. To achieve these objectives, we utilised the Biblioshiny of R-package bibliometric analysis tool to analyse the AI adoption literature. A total of 91 articles were reviewed and analysed in this study. Four major themes were identified: AI, machine learning, the unified theory of acceptance and …

Knowledge And Attitudes Of Medical Students About Research Methodology, Statistics, And Statistical Inference: An Assessment For Clinical Research Comprehension Skills, Laith Ashour, Lama Al-Mehaisen, Afnan Rababa, Osama Alrjoob, Moutaz Amayrh, Malak Al-Rabe'e, Qusai Al-Anasweh, Hala Al-Miqdadi, Nada Freihat, Mohammad Al Khreisha, Ala' Al Doaikat, Al-Mo'tasem Bellah Al-Rahamneh, Hamzeh Hatamleh, Fayez Zedat

Health Professions Education

Objectives: Medical students require a solid understanding of statistics in research papers. However, literature lacks sufficient studies on their proficiency, especially on Jordanian aspect. Methods: We performed a cross-sectional study on 361 medical students to evaluate their attitudes toward statistics, their knowledge in research methodology, and their ability to correctly interpret commonly used statistics in medical research. Statistical attitudes were assessed using three scales (value, difficulty, and interest) from the SATS-36 scale. Additionally, a novel author's-validated scale was created to measure students' research methodology knowledge. The scale validity was assessed using Confirmatory Factor Analysis (CFA). Multiple linear regression analysis was …

Beyond Clinical: A Proposed Policy Literacy Pathway In Health Sciences Education, Zarina Syed

Health Professions Education

Purpose: Health sciences graduates require not only clinical competence but also the ability to interpret, engage with, and enact policy. Yet, undergraduate curricula often emphasize technical skills, leaving gaps in policy literacy. Method: This conceptual paper proposes a scaffolded Policy Literacy Pathway to progressively integrate policy understanding across health sciences curricula. Results: Policy is framed as a dynamic, context-dependent process, aligning global ethical frameworks such as the Sustainable Development Goals with regional legislation and professional regulations. The pathway comprises four stages: Encounter, Iterative Engagement, Critical Reflection, and Policy Enactment. These guide students from initial exposure to policy issues through analysis …

The Role Of Application Questions In Identifying Underrepresented Applicants In A Doctor Of Physical Therapy Program: A Retrospective Cross-Sectional Study, Michael Bourassa, Allison Bourassa, Saurabh Mehta

Health Professions Education

Purpose: The underrepresentation of U.S minority groups in the physical therapy profession remains a persistent challenge, with student enrollment in U.S doctoral education programs being the main pipeline to increase representation within U.S healthcare fields. This study aims to examine the association between non-academic application questions and applicant diversity in a Doctor of Physical Therapy program. Methods: The main outcomes measured in this study include demographic and cognitive variables, as well as non-academic application questions, for a single DPT program admissions cycle. Demographic variables include race, gender, and age, while cognitive variables include GRE scores and GPA. General non-cognitive question …

Effectiveness Of 3d-Printed Models In Undergraduate Dental Endodontic Education: A Systematic Review., Razi Jalali, Shankargouda Patil, Frank W Licari, Kamran H Awan, Shilpa Bhandi

Health Professions Education

Purpose: With the development of flexible polymers and stereolithography, 3D printed models have been proposed for dental education to overcome the shortcomings of extracted natural teeth and artificial resin blocks. This review aimed to systematically review the literature available for the effectiveness of the use of 3D printed tooth models for undergraduate endodontic education. Methods: Based on the inclusion and exclusion criteria, PubMed, Scopus, Web of Science, and Google Scholar electronic databases were searched. Clinical studies with full-text articles available in the English language were selected. Data extraction, risk of bias assessment using the ROBINS-I tool, and assessment of the …

Determinants Of Postgraduate Education Pursuit Among South African Trained Paramedics: A Cross-Sectional Study, Naseef Abdullah, Patricia Mcinerney, Simpiwe Sobuwa

Health Professions Education

Introduction: The knowledge economy necessitates a highly skilled workforce, particularly in low- and middle-income countries (LMICs) navigating sustainable development trajectories. Within healthcare systems, paramedics represent a critical professional group whose advanced education directly impacts emergency care quality and system improve ment. While postgraduate qualifications are essential for paramedics to effectively develop and implement evidence- based emergency care and address unique healthcare challenges, the determinants influencing their educational advancement remain poorly understood. Methods: This descriptive cross-sectional study collected data from 265 Paramedics registered as Emergency Care Practitioners with the South African Health Professions Council through an online survey. Participants were recruited …

Professional Identity Development Among Nursing Students: The Impact Of Structured Reflective Practice, Abdelmonim El Fadely, Kamal Takhdat, Charaf-Eddine Ahraiba, Rahma Bouali, Sabah Selmaoui, Boujemaa Agorram

Health Professions Education

Purpose This study aimed to assess the impact of a structured reflective practice intervention on the development of professional identity among nursing students. Method A mixed-methods design was adopted. The intervention, based on guided reflective practice, was implemented with a voluntary sample of 58 participants. The evaluation relied on a quasi-experimental quantitative approach using the Macleod Clark Professional Identity Scale, with a comparison group and both pre-test and post-test measurements. A qualitative component was also included to explore the dimensions of the studied concept in greater depth. Results Quantitative findings showed a statistically significant difference between the post-test means (p < 0.001), indicating that the reflective practice intervention had a positive effect on the experimental group compared to the control group. The qualitative results further illuminated students’ reflections, which were organized into ten themes corresponding to the study’s conceptual framework: professional knowledge and skills, values and ethics, the nursing role, leadership, professional self-image, social image of the profession, sense of belonging, identification with role models, theory–practice integration, and career choice. These dimensions provided a comprehensive and nuanced understanding of professional identity, capturing the complexity of the concept. Conclusion These results support the integration of reflective practice as a pedagogical approach to fostering the construction and development of a positive professional identity. Professional identity, as a rich and multidimensional concept, goes beyond the process of professionalization—it represents its ultimate achievement.

Nursing Education In Indonesia And The Global Demand For Quality Healthcare: A Systematic Review, Evelyn Hemme Tambunan

Health Professions Education

Purpose: This study systematically reviewed evidence (2019–2025) on Indonesian nursing education, focusing on accreditation, competency based curricula, and workforce readiness in relation to global standards

Methods: Following PRISMA 2020 guidelines, a systematic search was conducted across Scopus, PubMed/MEDLINE, DOAJ/PMC, and policy repositories. Eligible sources included peer reviewed studies, systematic reviews, and policy reports related to nursing education in Indonesia quality assurance, competency based learning, and workforce demand.

Results: Twelve studies and reports were included, producing three themes: accreditation and quality assurance, competency based education and curriculum innovation, and workforce readiness and global alignment. Accreditation reforms, particularly Indonesia’s 2025 outcomes based …

Undergraduate Research Experiences Toward Student Success: Challenges And Opportunities For Medical Science Students At A University Of Technology, Ziningi Nobuhle Jaya

Health Professions Education

Purpose: The study aimed to evaluate the research experiences of undergraduate medical science students at a university of technology to identify challenges and opportunities and determine the affordances of research participation for student success.

Method: The study population comprised all third-year medical science students (n=30) enrolled in the research methods module, which is the only such module offered as part of the medical science academic program. Participation was voluntary and so the final sample represents a self-selected subset of fourteen individual from the full cohort. The data collection tool comprised closed and open-ended questions evaluating challenges, lessons learned, skills developed, …

Beyond The Numbers: A Mixed-Method Evaluation Of Faculty, Peer, And Self-Assessment Using Rubrics In Blood Pressure Determination Among Phase 1 Mbbs Students, Abeetha S, Chitra M, Suba A, B. Dharani, Sadhana S

Health Professions Education

Background: Competency-Based Medical Education (CBME) emphasizes formative, learner-centred assessment. Blood pressure (BP) measurement, a core clinical skill, integrates knowledge, skills, communication, ethics, and attitude. While rubrics are widely used to standardize evaluation, their utility in triangulating faculty, peer, and self-assessment in BP measurement remains underexplored.

Aim: To evaluate the reliability and educational value of rubric-based faculty, peer, and self-assessment in BP determination among Phase 1 MBBS students using a mixed-methods approach.

Methods: A cross-sectional mixed-methods study was conducted among 98 Phase 1 MBBS students in a South Indian medical college. Forty-nine students performed BP measurement, assessed simultaneously by 5 faculty …

Development Of A Faculty-Led Program To Improve Npte Readiness, Yaqiong Wang, Marlon Addison, Michael Hauber, Rachel Mcgraw, Karen Bock, Brendon Stewart

Health Professions Education

Purpose. The National Physical Therapy Examination (NPTE) is a multiple-choice examination that Doctor of Physical Therapy (DPT) students must pass to obtain licensure as physical therapists in the United States. Recent national data show a concerning decline in first-time pass rates, dropping from 91% in 2020 to 82% in 2025.¹ This downward trend is also reflected at our university. These findings underscore the need for effective strategies to enhance NPTE preparation. Therefore, the purpose of this study is to: 1) Describe a scaffolded model of faculty-guided exam preparation, designed to enhance students’ success on the NPTE during the months …

Design, Delivery And Impact: Practical Tips For Impactful Continuing Professional Development, Helen Mcgregor, Brett Vaughan, Louise Horstmanshof

Health Professions Education

Continuing professional development (CPD) is essential for maintaining competence and improving patient care, yet most approaches often have limited impact on practice. This Practice Brief draws on qualitative research with Australian allied health professionals to identify what motivates CPD engagement and supports meaningful learning. Participants highlighted that improving patient outcomes is the strongest driver, and that learning is most effective when it is relevant, actionable, socially interactive, and linked to real-world practice. We synthesised these insights into the PRACTICAL framework, outlining nine principles for CPD design: Patient Outcomes, Recipients, Actionable Takeaways, Co-design, Theory, Investment, Collaborative Learning, Assessment, and Link to …

The Need For A Validated Psychometric Scale To Assess Multidimensional Language Barriers In Medical Education Among Arabic Speakers, Ali Alfaifi, Nasser Shubayr

Health Professions Education

Language barriers significantly hinder academic performance, psychological well-being, and clinical communication skills of Arabic-speaking healthcare students educated through English-medium instruction. Although existing instruments focus on clinical communication—often among physicians—critical dimensions such as academic challenges and psychological impacts remain underassessed, and tools rarely address disciplines beyond medicine (e.g., nursing, pharmacy, radiology). Studies in Arabic-speaking contexts typically employ author-developed or adapted questionnaires lacking rigorous validation. This short communication underscores the need for a comprehensive, psychometrically sound scale tailored to Arabic-speaking healthcare students. Proposed dimensions include Language Proficiency, Academic Impact, Psychological Impact, and Clinical Communication. Validation will involve systematic item development, exploratory and …

Perceptions Of Managerial Roles In Physician Leadership Among First- And Final-Year Medical Students: A Cross-Sectional Study Using Mintzberg’S Framework, Sari Huikko-Tarvainen, Timo Tuovinen, Petri Kulmala

Health Professions Education

Purpose: This study investigated how medical students – as future physicians – perceive the relevance of Mintzberg’s ten managerial roles to physician leadership, and whether these perceptions change throughout medical education.

Method: In 2021, all first‑year (n = 116/116) and 98% of final‑year (n = 107/109) students at the University of Oulu, Finland completed a web‑based survey rating Mintzberg’s ten managerial roles in fulfilling physician leaders’ leadership work on a 5‑point Likert scale. Item reliability and internal consistency were examined with Cronbach’s α. Because Likert data are ordinal, medians and interquartile ranges (IQRs) were calculated, and group differences were tested …

The Role Of Participant–Clinician Relationality And Intervention Source In A Violence Reduction Trial: A Qualitative Study, Paul Leslie Simpson, Freya Stephenson, Patricia Morgan, Emaediong I. Akpanekpo, Jocelyn Jones, Peter William Schofield, Lee Knight, Tony Butler

Research outputs 2022 to 2026

Violence and domestic violence are global public health problems with prevention programs showing limited effectiveness. The form of delivery of such programs can influence their utility yet delivery characteristics are often poorly described. We analysed interviews with clinicians (n = 5) and participants (n = 12) involved in ReINVEST, a violence reduction clinical trial, to identify key elements of delivery. Three themes were identified: (1) clinician accessibility; (2) clinicians as participant advocates; and (3) humane care, reflecting participant–clinician ‘relationality’ as a central component of program delivery. We propose that this relationality is more likely to emerge in interventions delivered independently …

Mapping The Use And Psychometric Characteristics Of The Objective Structured Clinical Examination (Osce) In Musculoskeletal Physical Therapy Education: A Systematic Review, Luis Gómez Miranda, Tomás Reyes Amigo, Hernán Andrés De La Barra Ortiz

Health Professions Education

Purpose. Musculoskeletal disorders are a major cause of disability, underscoring the need for clearly defined and assessable competencies in physical therapy education. Although OSCEs are increasingly used in physical therapy programs, evidence regarding their design and psychometric properties is not yet fully characterized within musculoskeletal physical therapy education. This systematic review aimed to describe how OSCEs have been applied to assess musculoskeletal competencies in physical therapy education, summarize their structural characteristics and reported psychometric properties, and identify methodological gaps.

Method. A systematic review was performed according to PRISMA guidelines. Electronic searches were conducted in PubMed, Scopus, Web of Science, EBSCOhost, …

Study And Evaluation Of The Trimester System In Ksau-Hs, Saudi Arabia, Ayesha Mukthar, Sharon Pricilla Jeevan Kumar Leela, Suchithra Koipurathu Rajappan

Health Professions Education

Purpose: The study aimed to identify the perceptions of students, faculty and administrative staff in College of Science and Health Professions (COSHP), Al Ahsa campus, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), about the trimester system implemented in education sectors in the Kingdom of Saudi Arabia since the beginning of the Academic Year 2022-23 i.e. (1442) AH.

Methods: A cross-sectional study with a structured questionnaire of 30 closed-end items consisting of three sections was implemented. The first and second section focusses on the overall opinion, impact, and challenges observed as well as evaluating the trimester plan, the academic …

Firearm Violence In Health Care Professional Education In The United States: A Scoping Review., Kim D. Dao, Melissa D. Burgemeister, Sierra M. Hakanson, Audrey Rc Elias, Liana C. Wooten

Health Professions Education

Purpose: Despite widespread recognition of firearm violence (FV) as a public health crisis in the United States (US), gaps persist in understanding the education provided to health care professionals (HCPs) regarding prevention and management. This scoping review aimed to characterize FV education curricula for HCPs in the US, focusing on identifying target learners and understanding curricular content and implementation to inform future educational initiatives.

Methods: This scoping review was conducted according to Joanna Briggs Institute methodology for scoping reviews in PubMed, CINAHL, EMBASE, and Cochrane. Search terms included “health occupations”, “allied health personnel”, “gun violence/prevention”, “firearm violence/prevention”, “curriculum”, “education”, …

Clinical Spanish Instruction In Physical Therapist Education: A Quasi-Experimental Comparison Of Instructional Schedules, Rose M. Vallejo, Eric Kruger

Health Professions Education

Purpose: As the U.S. Hispanic population grows, patients with limited English proficiency encounter health disparities that compromise their care. As a result, clinical Spanish instruction in health professions education has become increasingly necessary to address these disparities. This study compared the effects of two instructional schedules: condensed (8-week) versus distributed (2-year), for a required clinical Spanish course in a physical therapist education program. A secondary aim was to implement a Spanish-language OSCE to assess functional communication proficiency.

Methods: Forty-eight students (mean age 25.0 ± 3.3 years; 54% female) from two consecutive cohorts received 16 hours of flipped classroom Spanish instruction. …

Centring The Audience: Attitudes And Behaviours In Australian Arts Organisations, Katya Johanson, Abbie Trott, Mark Taylor, Anne Kershaw, Hilary Glow, Tracy Margieson

Research outputs 2022 to 2026

Many arts organisations seek to increase the diversity of their audiences. Recent literature suggests that this requires organisations to interrogate and change their ways of operating. This is a fundamental shift for a sector that has long considered the goal of diversifying audiences as a problem external to the organisation. Responding to this discrepancy, this article compares attitudes and behaviours among workers in arts organisations, to identify whether staff see the need to make change and practise the behaviours required. It identifies and uses three organisational capabilities–‘dynamic capabilities’, ‘social networks’ and ‘business improvement processes’–to frame an analysis of a national …

Chronicles Of Film Tourism: An Integrative Review And Future Research Directions, Sangkyun Kim, Anton Klarin, Stijn Reijnders, Qijie Xiao, Nicky Van Es

Research outputs 2022 to 2026

This study triangulates historiographical and scientometric reviews to provide a systems perspective on film tourism. The three phases of historiographical analysis (exploration, growth, and maturity) correspond to the three clusters of scientometric analysis: (i) initial research exploring film tourism development and management, (ii) growing the field through studies on film tourists’ perceptions and practices, and (iii) reaching maturity through extending research into different cultural contexts and meaning-making processes. Based on the analysis, we offer a set of directions for future research, including the need to integrate sustainability research and film tourism studies in developing country contexts, as well as intertextuality …

07.02.01. Limpkin, Aramus Guarauna, D. C. Bryan, Ann Hodgson, Florida Ornithological Society

07.02. <em>Aramidae</em> - Limpkin

The Limpkin is an iconic Florida wading bird known for its specialized foraging on the native Florida apple snail.

Submicron Diamond-Assisted Irrigation Enhances Apical Biofilm Removal Under Sonic And Ultrasonic Activation: An Ex Vivo Study, Yung-Szu Hsu, Nai-Chia Teng, Sin-Yu Chen, Huan-Cheng Chang, Haw-Ming Huang, Sung-Chih Hsieh

Journal of Dental Sciences

Background/purpose:

Residual apical biofilm often persists despite sodium hypochlorite (NaOCl) irrigation with sonic or ultrasonic activation. Submicron diamond particles (SMD) have shown promise as a particle-assisted adjunct for root canal cleaning, but their effects on mature intracanal biofilm remain unclear. This study evaluated whether 500-nm SMD particles (10 mg/mL) improve the antibacterial and antibiofilm efficacy of saline or NaOCl irrigation against mature Enterococcus faecalis (E. faecalis) biofilms.

Materials and methods:

One hundred single-rooted human premolars infected with E. faecalis for 21 days were randomly allocated to ten irrigation protocols (n = 10). Antibacterial efficacy was assessed by …

Exosomes Derived From Bone Substitute-Induced Gingival Mesenchymal Stem Cells Promote Angiogenesis, Chongyu Shen, Zheng Guan, Rui Chu, Zhengyin Li, Jiangting Lu, Liangkun Xie

Journal of Dental Sciences

Background/purpose: In certain clinical bone grafting scenarios, bone substitutes frequently interface with the adjacent soft tissues. This study aimed to investigate whether deproteinized bovine bone mineral (DBBM) and coralline hydroxyapatite (CHA) induce paracrine responses in human gingival mesenchymal stem cells (GMSCs), thereby altering the pro-angiogenic capacity of their derived exosomes, and to profile specific cargo alterations.

Materials and methods: Exosomes were isolated from GMSCs co-cultured with DBBM (DBBM-G-EXO) or CHA (CHA-G-EXO), while native GMSCs-derived exosomes (G-EXO) were collected as controls. The angiogenic effects of these exosomes on human umbilical vein endothelial cells (HUVEC) were evaluated via cell proliferation, scratch wound …

Silencing The Mir-132/Sirt1 Axis Suppresses Nlrp3 Inflammasome Activation And Myofibroblast Differentiation In Oral Submucous Fibrosis, Ming-Yung Chou, Min Yee Ng, Yi-Wen Liao, Chuan-Hang Yu, Cheng-Chia Yu, Sin-Jia Tseng

Journal of Dental Sciences

Background/purpose

Oral submucous fibrosis (OSF) is a chronic oral potentially malignant disorder characterized by progressive extracellular matrix deposition, myofibroblast activation, oxidative stress, and inflammatory signaling. However, the upstream microRNA-mediated mechanisms linking fibrogenesis and NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome activation remain unclear. This study investigated the role of the miR-132/sirtuin 1  (SIRT1) axis in OSF-associated fibrotic and inflammatory responses.

Materials and methods

miR-132 expression was examined in OSF tissues, normal tissues, primary buccal mucosal fibroblasts (BMFs), and fibrotic buccal mucosal fibroblasts (fBMFs) using RNA sequencing and quantitative real-time PCR. Patient-derived fBMFs were transfected with a miR-132 inhibitor …

A Scientometric Study On Research Trends And Characteristics Of Kimura Disease, Zhongjing Lv, Yiming Luo, Wei Liu, Jian Yuan

Journal of Dental Sciences

Background/purpose: Kimura disease (KD) is an idiopathic condition that presents as a chronic, benign inflammatory disorder, typically affecting the head and neck region. The purpose of this study was to analyze the scientometric characteristics and research trends of KD.

Materials and methods: All the papers on KD were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2012 and after 2012 in the analysis of research trends.

Results: There were 925 papers on KD, with total citations of 10,821 and the h index of 47. Eosinophilia, lymphadenopathy, nephrotic syndrome, angiofollicular lymph node hyperplasia, …

Anemia, Hematinic Deficiencies, And Gastric Parietal Cell Antibody Positivity In Recurrent Aphthous Stomatitis Patients With Or Without Hyperhomocysteinemia, Yi-Ping Wang, Yu-Hsueh Wu, Yi-Pang Lee, Julia Yu-Fong Chang, Andy Sun, Chun-Pin Chiang

Journal of Dental Sciences

Background/purpose: Our previous study found that 42 of 430 recurrent aphthous stomatitis (RAS) patients have hyperhomocysteinemia. This study assessed whether these 42 RAS patients with hyperhomocysteinemia (hyperhomocysteinemia/RAS patients) had significantly higher frequencies of anemia, hematinic deficiencies, and serum gastric parietal cell antibody (GPCA) positivity than 388 RAS patients without hyperhomocysteinemia (non-hyperhomocysteinemia/RAS patients) or 430 healthy control subjects.

Materials and methods: The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 42 hyperhomocysteinemia/RAS patients, 388 non-hyperhomocysteinemia/RAS patients, and 430 healthy control subjects were measured and compared.

Results: We found that 42 hyperhomocysteinemia/RAS patients had significantly …