Digital Commons Network^™

Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik

AUIQ Complementary Biological System

Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …

Evaluation Of Circulating Hpg80, Ca15-3, Estrogen And Progesterone As Biomarkers In Breast Cancer Patients, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Muna Bufaroosha, Rahimi Yusop

AUIQ Complementary Biological System

It is very important to find reliable biomarkers for early detection and monitoring of treatment response because breast cancer is still one of the most common cancers in women around the world. The goal of this study was to find out how clinically important different biochemical markers are in Iraqi women with breast cancer. Some of these signs are progesterone (PG), oestrogen (E2), cancer antigen 15-3 (CA15-3), and circulating progastrin (hPG80). There were 100 women in this study, and they were all between the ages of 20 and 70. There were three groups of people who took part: a healthy …

Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi

AUIQ Complementary Biological System

Purpose: The glycoprotein molecule known as megalin is present on the proximal renal tubular epithelial cells. With an emphasis on megalin and cubilin levels in T2DM and IR patients, an area that obviously needs more research, this study attempts to give an outline of current knowledge of megalin function in relation to vitamin D and its metabolite (vitamin D receptor and vitamin D binding protein). Materials and Methods: This was a case control comparative study conducted at a endocrine and diabetes center in AL-Imamain Kadumain teaching hospital in Baghdad-Iraq. Study subjects were divided into three groups: 25 with T2DM with …

April 29, 2026 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Ofatumumab Associated Legionella Pneumonia In A Young Multiple Sclerosis Patient, Jobe Ashby, Omar Panhair

Books, Presentations, Posters, Etc.

Ofatumumab is the only anti-CD20 IgG1κ human monoclonal antibody therapy for relapsing forms of multiple sclerosis (MS) that patients can self-administer subcutaneously. Anti-CD20 agents are biologic therapies that carry an increased risk of serious infections, but rarely Legionellosis. We present the case of a young man taking ofatumumab for his MS who developed Legionella pneumoniae pneumonia. A 30-year-old man with MS diagnosed two years prior, stable on ofatumumab, presented with fevers, cough, and hemoptysis. A week earlier, he developed fevers and myalgias after administering ofatumumab, but these symptoms persisted longer than usual. Though initial vital signs were normal, he appeared …

Echoes Of Deception: The Historical Impact Of Propaganda And Disinformation On Public Opinion, Justina Zgaljardic

Honors Theses

This study reconceptualizes propaganda not as a collection of regime-specific messaging practices, but as a structured and adaptive system of perception management operating across political and ideological boundaries. Addressing fragmentation within existing scholarship, it examines how propaganda constructs legitimacy, organizes interpretation, and aligns individual cognition with state objects through recurring narrative strategies and disinformation mechanisms. Using a qualitative framework, the analysis draws on primary materials from four wartime cases: the Stalinist Soviet Union, Nazi Germany, the United States during World War II, and wartime Britain. The findings demonstrate that, despite variation in political systems, propaganda consistently operates through three interrelated …

Positive Factors Of Resilience In Marginalized Families, Amanda K. Rigsby

Doctoral Dissertations and Projects

The current study examined underexplored factors of resilience that help individuals overcome trauma. The study gathered insights from individuals in marginalized communities through semi-structured interviews and collected qualitative data for thematic analysis from 15 participants. The study identified polyvictimized individuals’ perspectives on (a) resilience, (b) regulation, (c) sense of purpose, and (d) mindfulness. Exploring the relationship between these areas could broaden our understanding and, in turn, inform targeted interventions through further studies. This study collected qualitative data through semi-structured interviews with individuals in the Appalachian region. The Resilience Portfolio Model has been used in research to identify mindfulness, regulation, sense …

Recognition Celebration 2026, Communications And Marketing

Faculty And Staff Recognition Dinner Programs

Award Winners:

University of Minnesota John Tate Award for Excellence in Undergraduate Advising: Marissa Holst

UMM Faculty Distinguished Research Award: Heather Peters

UMM Alumni Association Teaching Award: Cheryl Stewart

Community Engagement Award: Miriam Gieske

Morris Academic Staff Award: Jessica Porwoll

Mary Martelle Memorial Award: Marie Hagen

Outstanding Support Staff Awards: Tera Kleespie, Teresa Sayles, Rebecca Hamilton

Retirees: Kathy Dingman, Bart Finzel, Stephen Gross, Roland Guyotte, Arne Kildegaard, Athena Kildegaard

How To Build A Successful High School Sports Program, Jacob Jude Mulligan

M.S. in Leadership

The goal of this study was to explore the most influential factors for building a successful high school sports program. Through an expansive literature review, including testimonies from Hall of Fame coaches, themes emerged around the importance of Vision, Relationships, Belief, and Identity when it comes to the question of how to build a successful high school sports program. This research was conducted with the purpose of highlighting evidence of how these four themes have led to a positive culture and success for sports programs and athletes. This study is designed to help current and future high school coaches so …

Addition Of Gitr Agonist To A Dark Matter Cancer Vaccine And Anti-Pd-1 Increases Regulatory T Cell Numbers Without Appearing To Impact Therapeutic Efficacy, Rom S. Leidner1, Guo Hui Gan1, Christopher C. Paustian, Shawn M. Jensen

Books, Presentations, Posters, Etc.

Background: DPV-001 is an off-the-shelf cancer vaccine containing tumor associated proteins commonly overexpressed in adenocarcinoma and squamous cell carcinoma. It is enriched for short-lived proteins (SLiPs) and defective ribosomal products (DRiPs), including both canonical and non-canonical (or “dark matter”) antigens —comprising over 100 identified non-canonical microproteins. These antigens are delivered in spectrin-coated microvesicles that contain 5 TLR/ NOD agonists and 15DAMPs/molecular chaperones, and target CLEC9A+ conventional dendritic cells (cDCs). Preclinical models showed enhanced antitumor responses when the murine analog of DPV-001 (DRibbles) was combined with co -stimulatory agonists. Additional studies showed enhanced antitumor responses when co-stimulatory agonists were combined with …

Impacts Of Biodiversity In Short Rotation Woody Crop Production Systems On Water Quality, Nyla C. Jones

Honors Theses

Mitigating agricultural nutrient runoff and improving water quality are key challenges in meeting food and energy demands. To address this challenge, short rotation woody crops (SRWC), specifically Populus deltoides (eastern cottonwood) and its genotypes, can be planted at the interface of riparian areas and agricultural production fields to alleviate fertilizer runoff into adjacent bodies of water. This research employed an experimental design to evaluate the effects of P. deltoides diversity on tree productivity and nutrient uptake, and how it mitigates agricultural runoff. Ion exchange resins were deployed 0.5 meters below the soil surface at three different sites in Mississippi, each …

Beyond Beneficial Margins: Four Mechanisms Linking Border Vegetation To Pest Dynamics, Jorge F. M. Cardoso, Fabiane M. Mundim

Biology Student Research

Vegetated field borders are widely promoted as tools to enhance biodiversity and strengthen biological control in agroecosystems. However, their role in pest dynamics remains conceptually fragmented and empirically inconsistent. Here, we develop a unified framework explaining how crop border vegetation influences pest populations through four interlinked ecological mechanisms. First, borders act as host reservoirs and selective filters, providing alternative hosts and overwintering habitat that enhance pest persistence across crop cycles. Second, borders modify pest colonization dynamics by shaping movement, aggregation, and host-location behavior at crop edges. Third, borders restructure multitrophic networks, simultaneously supporting natural enemies, alternative prey, vectors, and pathogens, …

Allelopathic Potential Of The Invasive Calotropis Procera Plant Against Two Common Crop Plants In Taif Province, Maram Marzouk Aljuaid, Hatim Maatouq Al-Yasi, Tarek Mohamed Galal

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Invasive plants have several harmful impacts on the agroecosystem including modifying habitats, affecting food web characteristics, and affecting the ecosystem processes and functioning. This study aims to evaluate the allelopathic potential of the invasive plant C. procera and to assess its effect on seed germination and seedling growth of two common crop plants (barley and alfalfa). In a complete randomized design with three replications, the effect of different concentrations of the aqueous extract of the C. procera on the germination and seedling growth of the two crop plants was investigated. There is a marked decline in the germination percentage (GP) …

Global Research On Palm Oil Diseases And Infections: A Bibliometric Analysis, Fahmi Achmad Saputra, Indria Puti Mustika, Anna Safarida, Catur Sriherwanto, Nicky Rahmana Putra

Makara Journal of Technology

The sustainability of global palm oil production faces significant threats from a range of diseases and infections affecting palm oil crops. This study presents a comprehensive bibliometric analysis to map the scientific landscape and evolution of research related to palm oil diseases over the past decade. Using data from the Scopus database, 366 relevant documents were analyzed using R and VOSviewer to uncover trends in publication volume, citation impact, prolific authors, country contributions, and keyword co-occurrence networks. The findings reveal a strong research concentration on G. boninense, highlighting its critical role as a persistent pathogen in oil palm plantations. Emerging …

The Current Landscape Of Remote Patient Monitoring Regarding Diabetes Mellitus And Hypoglycemia: Protocol For A Scoping Review, Mathew J. Stephen, Baylor Akhavan, Melinda B. Chu, Kavita Batra, Roberto Sagaribay

Department of Medical Education Faculty Research

Background: Diabetes mellitus is characterized by impaired glucose regulation, predisposing patients to both hyperglycemia and hypoglycemia. Hypoglycemia, particularly frequent in insulin-treated individuals, remains a serious but underrecognized complication. Remote patient monitoring (RPM) technologies, such as continuous glucose monitors, smartphone apps, and hybrid closed-loop systems with remote monitoring capabilities, have emerged as promising tools to improve glycemic control and prevent hypoglycemia in nonclinical settings. Evidence examining the use of RPM technologies has expanded rapidly; however, the scope, characteristics, and reported outcomes of these interventions remain fragmented across modalities and settings. Objective: This scoping review aims to systematically map and describe the …

Psychology's Role In The Gender Pay Gap, Isabel Kraabel

Celebrating Scholarship and Creativity Day (2018-)

This paper explores the "good" and the "bad" history of psychology, specifically related the gender pay gap. The paper also investigates interventions and how we can move forward in the workplace and beyond.

Veratridine Suppresses Rictor-Mtorc2 Signaling Pathway In Colon Cancer Patient-Derived Xenograft Cells, Morgan Daniel Montgomery

Honors Thesis

Colorectal cancer (CRC) remains the second deadliest and fourth most common cancer in the world. The metastatic form of CRC is especially devastating due to a lack of effective and safer therapeutic options. Another challenge includes an increasing number of younger patients. Among critical signaling pathways overactivated in CRC, mTORC2 plays a key role in the progression of metastatic CRC, yet there is no selective mTORC2 inhibitor in the clinic. Interestingly, a natural plant alkaloid from the Veratrum genus, Veratridine (VTD), shows promise as VTD can upregulate UBXN2A, a colon-specific tumor suppressor protein. UBXN2A works with E3 ligases to ubiquitinate …

Breeding For Diverse Color And Protein Quality In Popcorn And Sweet Corn, Jonathan Niyorukundo

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Sweet corn and popcorn are important crops consumed globally as vegetable and snack, respectively. They are deemed healthy foods due to high fiber and carotenoid contents, especially in yellow varieties. Commercial varieties are optimized for high-yielding agronomics, and previous efforts were made to improve specific macro- and micronutrient contents. Both sweet corn and popcorn have poor protein quality due to the inadequate essential amino acids such as lysine and tryptophan. Moreover, commercial varieties are predominantly yellow, thereby offering no diversity of other maize colors, which are potentially healthier and more appealing to the consumer. In this project, we sought to …

Sleep And Autism Spectrum Disorder, Jennie Carlin

Dissertations, Theses, and Projects

Sleep disturbances are highly prevalent among children with Autism Spectrum Disorder (ASD) and may negatively affect daytime behavior, emotional regulation, learning, and overall family well-being. This quantitative research proposal examines the relationship between sleep difficulties, behavioral functioning, and family experiences among children with ASD. The study will explore how behavioral and environmental sleep interventions may influence sleep quality and nighttime behaviors, how improved sleep may contribute to changes in daytime behavior, and how parents and caregivers perceive the feasibility and effectiveness of implementing sleep-focused interventions at home. A quantitative research design will be used to collect caregiver-reported data through the …

Richard Thivener V. Andrew Nero

2026 Decisions

USDC for the Western District of Pennsylvania

Induced Membrane Reconstruction (Masquelet Technique) For An Open Pilon Fracture With Segmental Bone Loss: A Case Report, Courtney Gaines, Andrew Silman, Dylan Patel, Akhil Reddy

Advocate GME

No abstract provided.

Optimized Bombax Ceiba/Jute Hybrid Epoxy Composites For Enhanced Thermal Insulation Performance, Shadman Ahmed Khan, Naeem Ahmmed, Md Tanvir Hossain, Abdullah Ibn Asheque, Md Ariful Islam, Md Abdul Kader, Md Sohel Rana, Sakib Masud

Michigan Tech Publications

The development of sustainable hybrid natural-fiber composites provides a practical way toward lightweight materials with tailored mechanical and thermal performance. In this study, Bombax ceiba (BC)/jute hybrid epoxy composites were fabricated using a stacked preform followed by compression molding, and the effect of fiber blending ratio on mechanical, thermal, and microstructural properties was systematically investigated. Three compositions-40/60, 50/50, and 60/40 BC/jute by weight-were evaluated. Mechanical testing showed that the J50 composite, with a balanced fiber ratio, exhibited superior flexural strength and impact resistance, indicating effective hybrid synergy and improved stress transfer between fibers and the matrix. Thermogravimetric analysis showed that …

Inhibition Of Epac1 Prevents Neuronal Death Mediated By Diesel Exhaust Particles In Ferroptotic Cell Death Conditions, Hong Yan, Leshan Zhang, Ana L Manzano-Covarrubias, Phoeja S Gadjdjoe, Anja Land, Christina H J T M Van Der Veen, Teresa Mitchell-Garcia, Heba A Fayyaz, Marco Venema, Christoffer Åberg, Marieke Van Der Hart, Frank Lezoualc'h, Xiaodong Cheng, Amalia M Dolga, Martina Schmidt

The Brown Foundation: Institute of Molecular Medicine

Air pollution is a growing hazard to global health. Epidemiological studies have reported a potential role of air pollutant exposure in the development or aggravation of neurodegenerative diseases. However, the underlying mechanisms are ill-defined. Ferroptosis is an iron- and reactive oxygen species (ROS)-dependent form of cell death that drives neuronal loss in neurodegenerative diseases. Our previous studies reported the involvement of adenosine 3',5'-cyclic monophosphate (cAMP) and EPAC (exchange protein directly activated by cAMP) in ferroptotic cell death. Here, we investigated the effects of diesel exhaust particles (DEP) in mouse hippocampal (HT22) neuronal cells. Our data showed that toxicity induced by …

Analysis Of Bacterial Virulence And Resistance In A Model Of Recurrent Uti, Rachel L. Proper

Undergraduate Honors Theses

Urinary tract infection (UTI) is a major women’s health issue, affecting approximately 40% of women during their lifetime. Formation of a biofilm by UTI-causing bacteria poses a major challenge in treatment, as the protection provided by the biofilm hinders both host defenses and antibiotic treatment. Failure to eradicate these infections causes them to become recurrent (rUTI). Previous research indicates that rUTI may be comorbid with a mutation in the SERPINE1 gene, which causes fibrin to accumulate within the body. Literature also indicates that fibrin provides a better scaffold for bacterial attachment and, subsequently, biofilm formation. In this work it was …

The Influence Of Humility And Spirituality On The Relationship Between Work-Family Conflict And Mental Help-Seeking Attitudes In Skilled Trade Workers, Charles Dean Twellmann

Doctoral Dissertations and Projects

This quantitative study examined the relationships among work-family conflict (WFC), humility, spirituality, and mental help-seeking attitudes (MHSA) among skilled trade workers in the United States. Skilled trade occupations are characterized by demanding schedules, physical labor, safety risks, and cultural norms emphasizing independence and self-reliance, factors that may influence occupational strain and attitudes toward psychological support. Although WFC and help-seeking have been examined in other high-demand professions, limited research has explored how humility and spirituality relate to these constructs within skilled trade populations. Validated self-report measures of WFC, humility, spirituality, and MHSA were administered to 196 skilled trade workers who were …

Unleashing Stress: The Effects Of Training, Bond Strength, And Stress On Pet Dog Behaviors And Health, London Maria Wolff

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Humans and dogs have formed a unique ability to communicate with each other through evolutionary and developmental mechanisms. This increased communication serves to form dynamic interspecies bonds by facilitating learning and training over the lifetime of a dog. However, it is not known what factors permit the unique capacity of dogs to form bonds with, and learn from, their human companions. Odor is a notable candidate for interspecies communication about emotional states, with studies showing that both dogs and humans use odor information to detect human emotions (Calvi et al., 2020). Possibly, this may include detection of both acute and …

The Right Time For A Synapse To Change: Windows And Mechanisms Of Multiday Training Trials, Rong-Yu Liu, Yili Zhang, Roberta Calvo, Paul Smolen, John H Byrne

Faculty, Staff and Student Publications

Although learning over multiple days is more effective than a single day of training, the underlying cellular mechanisms of repeated training trials remain poorly understood. With a combination of empirical and computational approaches, we determined a critical time window for a second stimulus block of a multiday training protocol to augment long-term synaptic facilitation (LTF) of the Aplysia sensorimotor synapse and long-term enhancement of neuronal excitability (LTEE), two cellular correlates of learning and memory. A second stimulus block delivered 24 h after the first block significantly enhanced LTF and LTEE, but was without effect at 18 or 32 h. This …

2026-04-29 10 Foot Rideable Sea Slug Brings ‘Toxic Beauty’ To Cannonball Arts, Hannah Mwangi

The Spectator Online

No abstract provided.

Cooperation And Conflict: Oswald Veblen And Abraham Flexner, Juan Carvajalino, Della Dumbaugh

Department of Math & Statistics Faculty Publications

In 1929, Caroline Bamberger Fuld and her brother, Louis Bamberger, sold their department stores, Bamberger & Co., at a particularly timely moment. They invested their sizeable fortune in a new academic initiative in America, an institute devoted to research that would go by the name of the Institute for Advanced Study. This paper introduces two colleagues, Abraham Flexner and Oswald Veblen, and explores the cooperation and conflict between them as they worked alongside one another to shape the Institute for Advanced Study and the School of Mathematics within it.

University Philharmonic Orchestra & Mixed Chamber Ensembles

Bailey School of Music Concert Programs

Nancy Conley, Conductor