Digital Commons Network^™

Simultaneous Carrier, Cargo, And Functional Tracking Of Lipid Nanoparticles, Hannia Vanessa Balcorta Muñoz

Open Access Theses & Dissertations

Lipid nanoparticles (LNPs) have become effective delivery vehicles in nanomedicine, particularly for nucleic acid-based treatments. However, a major limitation remains in the field regarding the simultaneous monitoring of the nanoparticle carrier, its encapsulated payload, and the resulting functional protein production in both in vitro and in vivo systems. Furthermore, traditional lipophilic dyes employed for labeling LNPs frequently exhibit incompatibility with tissue-clearing methods, such as CLARITY, due to signal loss following lipid removal. This research developed and evaluated a new fluorescent labeling method using CM-DiI, a dye that reacts with thiols, for multimodal tracking of LNPs. CM-DiI was included in the …

Things Montaigne Got Right About Medicine, Stewart Justman

Global Humanities and Religions Faculty Publications

In an article in Perspectives in Biology and Medicine a few years ago, I documented a number of Montaigne’s insights into medicine that have held up over time.  Not everyone was convinced.  Therefore I here augmented my case, adducing several other Montaignean insights and adding some particulars to one or two that were mentioned in the original article.

Tiny Tusk Internship: Gut Instincts: A Review Of Literature On The Impact Of Breastfeeding On The Infant Gut Microbiome, Rayla Payne

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The purpose of this systematic review was to investigate both the short- and long-term benefits that breastfeeding has on the infant gut microbiome. The PICOT question was: In full-term infants, how does exclusive breastfeeding compared to mixed or formula feeding influence the diversity and composition of the gut microbiome throughout the first 12 months of life? For this research, EBSCOhost, CINAHL, and the National Library of Medicine databases were searched to find relevant studies and systematic reviews. Terms such as “breastfeeding and infant gut microbiome” were used to conduct the search. Other terms used included “breastfeeding OR formula feeding”, “human …

The Physiological And Psychological Effects Of Social Media Addiction: A Mixed Methods Study, Ella M. Roper

Biological Sciences Undergraduate Honors Theses

Abstract

Objectives: This study sought to examine the physiological and psychological effect of social media addiction displayed through sleep quality, cortisol levels, heart rate, and emotional affect in students at the University of Arkansas.

Methods: Seven adults (Age range = 18-21; 100% female) participated in a mixed-methods study investigating social media addiction across a two-week period. Sleep quality and duration were assessed using the Pittsburgh Sleep Quality Index (PSQI). Participants provided saliva samples which were used to quantify cortisol levels. For two weeks, participants were asked to spend at least ten minutes on social media daily and to report their …

Can Methanogens Grow On Asteroids?, Isabella N. Reimer

Biological Sciences Undergraduate Honors Theses

Because of asteroids’ chemical features, they may serve as potential environments for life and are of interest in astrobiology. Dr. Kral’s laboratory studies methanogens, microorganisms in the domain Archaea, as possible life forms on extraterrestrial bodies. Since some methanogens can withstand harsh environmental conditions and produce methane as a waste product, methane production can be used as an indicator of potential microbial activity.  In this study, three methanogen species, Methanothermobacter wolfeii, Methanobacterium formicicum, and Methanosarcina barkeri were tested for growth on asteroid simulants based on the Orgueil (CIE-1) and Murchison (CME-1) meteorites. First, methanogen growth was assessed in the …

Developing Warning Signage For Harmful Algal Blooms At Lake Fayetteville, Abigail R. Evans

Biological Sciences Undergraduate Honors Theses

The presence of harmful algal blooms (HABs) poses many risk factors for human health, and once microcystin concentration has reached a certain level, that water source will be closed for the duration of the bloom. Agencies tend to use static signage with limited information to inform the public about the current status of the water, but a sign similar to the one used by the National Fire Danger Rating System can allow for constant updates detailing specific risk levels for the public. Using previously reported data on Lake Fayetteville, thresholds for risk factors that are easily measurable were determined. The …

The Genetic Basis Of High Transformation Efficiency In The Model Yeast Saccharomyces Cerevisiae, Mary Kathryn E. Cheek

Biological Sciences Undergraduate Honors Theses

Transformation, a type of horizontal gene transfer, describes the uptake, maintenance, and integration of environmental DNA by cells. Despite the known effects of transformation on evolutionary processes, little is known about the genetic basis of this phenomenon. Saccharomyces cerevisiae is a eukaryote able to transform at quantifiable rates when made chemically competent and treated with a heat shock. S. cerevisiae also has variation in transformation efficiencies between various strains, and high recombination rates allow for sufficient allele “shuffling” in intercross populations. This project utilizes a bulk segregant analysis approach to compare sequencing data between transformant pools and non-transformant pools of …

The Role Of Cognitive Inhibition In Creative Problem Solving, James Schnoes

Biological Sciences Undergraduate Honors Theses

Creativity is a defining characteristic of human cognition and plays a central role in shaping our daily lives. In the literature, creativity is commonly conceptualized through two cognitive processes: divergent thinking, which involves generating multiple novel ideas, and convergent thinking, which involves arriving at a single correct solution by integrating all information available. (Cropley, 2006; Guilford, 1959; Runco & Jaeger, 2012). The present study examined how cognitive control, measured via the Stroop task (Stroop, 1935), relates to convergent creative problem solving as assessed by the Compound Remote Associates (CRA) task. Additionally, trends in alpha and theta power spectra during the …

The Effect Of Facial Adiposity On Hypothetical Medical Treatments As A Function Of Disgust, Lindsey Duran

Biological Sciences Undergraduate Honors Theses

Perceivers are capable of estimating the health of individuals through cues to facial adiposity, with such inferences having accuracy in recognizing worse chronic health among those exhibiting greater adiposity. Nonetheless, these inferences could extend beyond health assessments into subsequent anti-fat prejudice based on perceptions of such individuals as pathogenically threatening. Although potentially functional in ancestral contexts, modern healthcare settings could render this functional stigmatization a liability that results in worse medical care toward those with higher adiposity. In this study, I tasked medical workers to evaluate male and female hypothetical patients at high and low levels of facial adiposity, particularly …

Parental Monitoring And Approval As Moderators Of Peer And Parental Influences On Adolescent Drinking, Clara Pool

Biological Sciences Undergraduate Honors Theses

Adolescence (i.e., ages 12 to 18) is a developmental period marked by exploration and risk-taking behavior, which is often associated with increased risk for alcohol use. Adolescents’ perceptions of what is typical or approved behavior within their social environments (e.g., peers, parents) may be associated with their drinking behaviors. Parental monitoring is related to reduced substance use risk, though peer and parental influences can interact. For example, adolescents who perceive their parents do not approve of adolescent alcohol use may be less susceptible to alcohol-approving peers. Therefore, this study examined how adolescents’ perceptions of peer approval, parental approval, and parental …

Objects Against Erasure: Literary Materiality In Tommy Orange’S There There And Oscar Hokeah’S Calling For A Blanket Dance, Paige Hinton-Franciotti

Theses & ETDs

No abstract provided.

Reigniting Identity: Rediscovering My Teaching, Lifelong Learning, And Myself, Rachel Griffith

Master of Arts in English Plan II Graduate Projects

A culmination of two years of work and self-discovery represented through three different types of writing, two academic and one creative. The academic works explore communication and autism in the English classroom, as well as teaching technical writing in practice ways. The creative work is a poetry portfolio that is one of the author's proudest works from their degree track, covering a variety of topics from love to nostalgia to inner turmoil. Together, they narrate three reasons why the author writes, teaches, and lives.

May 2026 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean's Office Communication Team

Library & Learning Newsletters

PDF version of the May 2026 (Volume 4, Issue 10) Library & Learning Newsletter.

Enhancing Methods For Load Rating Bridge Timber Piles, Aashish Ghimire

Graduate Theses and Dissertations

Timber piles are widely used in bridge foundations across the United States due to their low cost and ease of installation. The strength of a timber pile is dependent on many factors including wood species, unbraced length, support conditions, age and cross-sectional properties. Cross-sectional properties are highly impacted by the progression of biological deterioration which often is undetected when using standard DOT inspections methods. Current inspection practices rely primarily on subjective methods that provide limited quantitative information about a pile’s existing load-carrying capacity. Consequently, timber piles are inaccurately assessed and prematurely replaced. In response, this thesis investigates the relationship between …

May 2026, Office Of Research

Research Update

No abstract provided.

The Environment, Health, And Vector Nexus: Evaluating The Spatiotemporal Variability And Societal Impact Of Ticks In Arkansas, Dalton Williams

Graduate Theses and Dissertations

Tick-borne diseases (TBDs) are a surging public health and veterinary concern in the United States. In states like Arkansas, climate change and shifting land use have recalibrated the ecological niches of vector species. This research utilizes species distribution and ecological niche modeling to assess the spatiotemporal suitability of ixodid tick habitats, specifically where environmental and socioeconomic factors intersect. By integrating spatial science with public health frameworks, this study identifies priority intervention areas in underserved rural regions where healthcare resources are often constrained. This study provides a comprehensive methodological framework, leveraging remote sensing datasets and historic disease data to delineate exposure …

The Effects Of Fluency Building On Undergraduate Student Performance, Lauren B. Shibley

Dissertations

Online learning has become integral to higher education, with enrollment steadily increasing over the past decade and accelerating during the COVID-19 pandemic. Research highlights the importance of flexibility, learner autonomy, and self-regulated learning skills in this environment, with studies demonstrating that strategies such as mastery-based, self-paced instruction, fluency training, and timely feedback support student engagement and academic success. Early work adapting personalized instruction for online use (Pear & Crone-Todd, 1999) and subsequent studies on fluency practice (Quigley et al., 2018; Urbina et al., 2019) emphasize how these supports can improve concept retention. Despite these advances, more quantitative research is needed …

Increasing Pride Skills For Child Engagement Using Cdi-Only Ipcit With Children With Autism Spectrum Disorder, Jordan T. Etherington, Zachary C. Labrot, Emily R. Defouw, Brad Dufrene, Brittany D. Garza, Amarah Sweaks, Briley Newcomb

Faculty Publications

Many children with autism spectrum disorder (ASD) display elevated levels of challenging behaviors and decreased social engagement. Parent Child Interaction Therapy (PCIT) may help children with ASD increase rates at which they engage and interact with their caregivers. Existing barriers to treatment completion, including high attrition and travel time and costs, may be ameliorated by delivering PCIT virtually (iPCIT) and setting attainable mastery criteria. This study utilized a multiple baseline design across three caregiver-child dyads with ASD to determine whether an iPCIT protocol affected caregivers’ use of positive engagement skills, children’s engagement, and children’s challenging behaviors. Results demonstrated increased and …

Developing Transparent Sustainability Data Systems In A Poultry And Pet Food Company: An Internship Case Study, Catherine L. Warren

Biological and Agricultural Engineering Undergraduate Honors Theses

My honors thesis examined my internship experiences and its implications on sustainability data gathering and reporting in poultry and pet food companies. It highlighted my internship projects, the skills I developed, and the connections to sustainability data transparency and reliability in a corporate environment.

In my thesis, I shared details about my internship. I described what projects I worked on, the places I visited, the hands-on experience I gained, and the different teams I worked with throughout the internship duration. I discussed the analytic and professional skills I developed through conducting a waste audit, developing Tableau dashboards, and helping to …

Design And Performance Overview Of The Inaugural University Of Arkansas Beng Fountain Wars Team, Autumn Jones

Biological and Agricultural Engineering Undergraduate Honors Theses

This honors thesis describes the engineering design process for the first ASABE Fountain Wars submission by a student team at the University of Arkansas in over a decade. Fountain Wars has a technical and aesthetic task, and the focus of this thesis is the design of the technical task. In 2025, this task was the “shoot out.” The objective was to get objects from a small pool into two 5-gallon buckets 10-15 feet away. The power for initiating the launch had to be provided by the pump. The objects were required to start at the surface of the water.

The …

Dried Water Treatment Residuals Might Be An Option To Reduce Soluble Reactive Phosphorus Release From Soils, Katie B. Mckay

Biological and Agricultural Engineering Undergraduate Honors Theses

Nonpoint source pollution from agricultural landscapes contributes to freshwater eutrophication, with legacy phosphorus (P) in soils potentially driving soluble reactive phosphorus (SRP) losses to surface waters. The objectives of this study were to evaluate SRP adsorption by dried water treatment residuals (WTRs) produced by Beaver Water District, quantify reductions in soil SRP release across increasing WTR application rates, and compare dried WTR performance to prior WTR studies.

Dried WTRs (~98% solids) were assessed using batch sorption experiments and soil core incubations. Phosphorus sorption was measured by mixing WTRs with CaCl₂ solutions containing increasing SRP concentrations and fitting results to …

Monitoring Streambank Morphology Using Iphone Lidar Technology, Lily C. Stitt

Biological and Agricultural Engineering Undergraduate Honors Theses

Monitoring stream morphology is crucial for maintaining the health and safety of fluvial environments, particularly as these naturally dynamic systems are shifted out of equilibrium due to climate and land-use change. Quantifying changes in stream geometry are useful for infrastructure design, water quality assessment, water resource management, and stream restoration, among other applications. Traditional stream surveying methods contain numerous cost limitations that inhibit affordable and accessible stream surveying needed for evaluating stream geometry with high accuracy and larger spatial scales (>100s of ). In recent years, several advancements have been made in the use of Light Detection and Ranging …

Cross-Facility Reliable Deep Learning Based Beef Marbling Assessment Via Unsupervised Domain Adaptation Regression, Samuel Vinson

Biological and Agricultural Engineering Undergraduate Honors Theses

Inconsistent quality grading in beef production leads to inefficiencies, economic disparity, and consumer mistrust. While USDA meat grading traditionally relies on skilled visual inspectors, these human evaluations suffer from cross-facility variability and subjectivity. This paper introduces the first known application of unsupervised domain adaptation regression for cross-facility beef marbling score prediction—an innovation that improves generalization across diverse environments in the beef supply chain. Utilizing numerical scores ranging from 100-900, the research employed convolutional neural networks (CNNs), including ResNet, VGG, and AlexNet architectures. The study specifically introduced and validated a unified unsupervised domain adaptation regression method using the ResNet-50 architecture to …

Uav-Based Sensor Integration For In-Situ Lake Water Quality Monitoring, Alec R. Campbell

Biological and Agricultural Engineering Undergraduate Honors Theses

Surface water monitoring is often constrained by limited spatial and temporal coverage due to the labor-intensive nature of traditional sampling methods, particularly in environments that are difficult to access or pose safety risks. Unmanned aerial vehicles (UAVs) offer a promising solution by enabling more frequent, spatially distributed, and cost-effective data collection. This study presented the design, development, and field evaluation of a UAV-based system for real-time, in-situ water quality monitoring. The system integrated multiple sensors, including oxidation-reduction potential (ORP), RGB spectrometry, pH, electrical conductivity (EC), dissolved oxygen (DO), and a multispectral spectrometer within a UAV platform.

Field testing was conducted …

Per- And Polyfluoroalkyl Substances (Pfas) In Cave And Withrow Springs, Arkansas, Luke A. Ahlemeier

Biological and Agricultural Engineering Undergraduate Honors Theses

The class of chemicals known as Per- and Polyfluoroalkyl Substances (PFAS) are believed to be widespread in the natural environment, but the full extent of PFAS prevalence is not well understood, particularly in karst springs. The objectives of this study were to (1) collect water samples from Cave Springs and Withrow Springs, Northwest Arkansas, (2) measure for concentrations of 40 PFAS compounds using EPA Method 1633, and (3) compare differences in PFAS concentrations and discuss potential sources of PFAS for each spring. Each spring was sampled on September 29, 2025, October 13, 2025, and November 10, 2025, and water samples …

A Systems Approach To Nitrogen Fertilizer Management: Modeling Emissions And Runoff Pathways In Arkansas Agriculture, Avonelle Lindon

Biological and Agricultural Engineering Undergraduate Honors Theses

Nitrogen fertilizer management is a critical challenge in modern agriculture. This thesis develops a system dynamics model of nitrogen in Arkansas rice and corn systems to explore barriers to translating agricultural research into practical farmer guidance.  The modeling process revealed key challenges: (1) scarcity of Arkansas-specific factors and best management practice (BMP) effectiveness data; (2) tension between model comprehensiveness and accessibility; (3) misalignments in conservation incentive structures; and (4) difficulty in validating models without field measurements. The resulting model demonstrates basic nitrogen cycle processes and BMP integration, but validation against published literature revealed significant issues with predictive accuracy. These findings …

Preserving The Past: Exploring The Last Frontier's Ecosystem Shifts And Biodiversity Of The Tallgrass Prairies, Gisell Maldonado, Amelia Villaseñor

Anthropology Undergraduate Honors Theses

In North America, grasslands are a cornerstone of the environment. Historically, the tallgrass prairie was expansive and reached from Manitoba in Canada to Texas. Today this unique ecosystem is highly fragmented and reduced, but it remains an important ecosystem for biodiversity and cattle management. While there are many complex ecological interactions in the prairie, recent research shows that large herbivores are vital in maintaining grasslands through grazing and other behaviors that reduce woody encroachment and support nutrient cycling. Here, we examine cow and bison dietary behaviors and connect these to the ecosystem services provided by these large herbivores. In the …

Primate Craniofacial Trauma And Its Relationship To Socioecological Factors, Kaitlyn Harden R. Harden

Anthropology Undergraduate Honors Theses

Postmortem analysis of the skeleton can reveal patterns of trauma that have accumulated over an individual’s lifetime. Patterns of trauma within a species can also provide key insights into how that species lived and reflect aspects of their socioecology and life history. Research has been conducted often on postcranial trauma, but is rare regarding the craniofacial region and has not been examined broadly across primates. To fully understand patterns of trauma in primates, rates of trauma must be compared and placed into context of a variety of socioecological factors. To do so, I examined hypotheses including that species with higher …

A Dyadic Mixed Methods Study Of An Online Asynchronous Acceptance And Commitment Therapy Intervention For Individuals Diagnosed With Dementia And Their Caregivers, Gavin Brendan Green

All Graduate Theses and Dissertations, Fall 2023 to Present

A dementia diagnosis can be overwhelming for both the person diagnosed and the people who care for them. Many experience stress, uncertainty, and emotional strain, yet most support programs require significant time and are difficult to access. This study examined a brief, online program called the Compassion Compass, designed to provide early emotional support for both individuals living with dementia and their caregivers.

The program is based on Acceptance and Commitment Therapy and can be completed in about 30–45 minutes. It focuses on helping individuals notice difficult thoughts and emotions, reconnect with what matters to them, and take small, …

Immigrants And The Battle For Our Nation In The Courts, Raquel E. Aldana

University of the Pacific Law Review

No abstract provided.