Digital Commons Network^™

Reptiles Of The Northeastern Piedmont Of South Carolina, Steven E. Fields

Journal of the South Carolina Academy of Science

No abstract provided.

Clethra Alnifolia: A Fact Sheet For Seed Transfer Considerations, Taylor Houggy

Plant Science Articles

Clethra alnifolia is a highly prized fragrant deciduous shrub, often found in many home gardens across Eastern North America. Despite its popularity in the landscape industry, there is little research comparing C. alnifolia's natural habits in the wild to its habits as a landscaped cultivar. Information such as flowering phenology, genetic diversity, and growth habits have the potential to change considerably depending on C. alnifolia's location. Because of this, it is important that landscape growers as well as forest conservationists have access to ecological fact sheets in order to make informed decisions when transferring seed to different areas. In this …

Great Graminoids! Quantifying Vegetation On Roan’S Western Balds Over The Last 80 Years (1936, 1956, 2016), James T. Donaldson

Faculty Open Access Works

PowerPoint originally presented at Friends of Roan Mountain Winter Naturalists' Rally 11 Feb. 2017.

Grant funding from Friends of Roan Mountain for resampling historic transects from Carvers Gap to Grassy Ridge. Revised 2021, 2022, & 2023 (technical features and diversity); edited for clarity 2026 (for written rather than oral presentation & added references slide).

From Stranger To Self: The Role Of Familiarity In Modulating The N170 And N250 Erp Components, Tabish Gul

Dissertations

This study investigated how varying levels of face familiarity modulate the N170 and N250 event-related potential (ERP) components, two neural markers of face perception and recognition. While the N250 is widely considered familiarity-sensitive, the N170 has traditionally been linked to the structural encoding stage of face perception. However, recent research suggests that face familiarity may also influence N170 amplitude and latency. While most previous studies have compared up to three familiarity levels, the present study examined five levels of familiarity: own face, friend’s face, famous face, experimentally familiar face, and unfamiliar face. Twenty-six participants viewed face images while completing a …

Brachial Macroparasite Loads In Estuarine Young-Of-Year Striped Mullet (Mugil Cephalus), Triston Rice

Honors Theses

Climate change is a growing threat to marine habitats globally. One ecological impact that warming water temperatures poses is the increased metabolic rate of many parasite species. Their promoted reproductive and feeding rates could pose a threat to the stability of many host populations. Parasites of the gills, or brachial parasites, are especially concerning to fish populations globally. As parasitism is not limited to a specific taxon and comprises a large diversity of ecomorphs and behaviors, geographically distinct areas may be differentially affected by the changing prevalence of parasites. This study aimed to survey current brachial parasite abundance and prevalence …

Neuroprotective Effects Of Estradiol And Genistein And Interactions With Aromatase Inhibitions Post Cerebellar Lesion In Male Zebra Finches, Grace E. Thompson, Anthony P. Irovic

Honors Theses

Across vertebrates, peripheral and brain-derived estradiol (E₂) promotes neuroplasticity. After injury, E₂ can be derived locally from testosterone via aromatase (AROM), an enzyme that is upregulated in glia at the site of neural injury. E₂disrupts testicular function and elevates cancer and stroke risk, primarily via binding to estrogen receptor alpha (ER α). Genistein (GEN), a phytoestrogen, is similar to E₂ but binds preferentially to estrogen receptor beta (ER β). It may offer neuroprotection without adverse effects of E₂. We used adult male zebra finches (ZF) to model neuroprotective effects of E_{2 …}

Barriers And Opportunities In Women-Led Dental Entrepreneurship, Eliza Grace Ulmer

Honors Theses

Barriers and Opportunities in Women-Led Dental Entrepreneurship

This research examines the barriers that women encounter when attempting to open their own business. Specifically, this research will concentrate in the dental field and health care industry. Attaining the education, skills, knowledge and criteria to become a licensed dentist is extremely difficult. Adding the licensed dentist opening their own practice adds another layer of difficulty. These challenges are further compounded when the practitioner is a woman.

This research interviewed women dentists in the business as well as entrepreneurs that opened their own health practice. These interviews showed the process and requirements needed …

A Transgenerational Analysis Of Factors Influencing Fertility Among Jamaican Men, Shanique Deniellia Essuman

Walden Dissertations and Doctoral Studies

No abstract provided.

Exploring The Skills Gap And Implications Of Science Technology Engineering And Mathematics Graduates And Professional Laboratory Staff, Indrajee Wewaliyadda

Dissertations, Theses, and Projects

The noticeable expansion of the biotech and research industries, fueled by increased funding due to the 2019 pandemic (Wallace et al., 2022), which increased the existing skills gap among fresh STEM graduates entering professional laboratories. This study aims to evaluate whether bachelor’s degree holders in biological sciences possess the necessary laboratory competencies to meet professional demands. Utilizing survey methods and Kolb’s experiential learning model (Kolb, 1984), the research examines the extent and implications of the skill deficiencies observed. The study helps to understand the gap in practical laboratory skills among new graduates. Further, results from this work will show the …

Exploring The Impact Of Ungrading On Student Engagement And Motivation In A First-Year Composition Class, Mary B. Gruis

Dissertations, Theses, and Projects

This study investigated the association between student engagement, motivation, and self-efficacy in college-level writing-intensive courses using an ungraded approach. Motivated by disillusionment with traditional grading methods and inspired by texts on equitable grading and culturally responsive teaching, the researcher explored how ungrading could foster deeper learning and equitable educational practices. Grounded in Bandura’s (1997) self-efficacy framework, this qualitative case study examined the lived experiences of first-year composition students at a two-year institution. Data collection included student interviews, student reflections, and an instructor interview. The analysis revealed themes aligned with self-efficacy, engagement, and motivation, suggesting that ungrading positively impacted students' perceptions …

Cloud-Deployed Rna-Seq Analytics For Identifying Imaging And Therapeutic Targets In Chemotherapy-Induced Toxicities, Zhimu Wang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Chemotherapy has significantly improved cancer survival rates; however, many anticancer agents induce severe acute and chronic side effects that substantially reduce patient quality of life and limit therapeutic efficacy. Despite their clinical importance, the molecular mechanisms underlying chemotherapy-induced toxicities across different organs remain incompletely understood, in part due to the lack of integrated, scalable, and accessible analytical platforms capable of synthesizing large transcriptomic datasets across tissues and experimental models.

This thesis describes the development of a cloud-deployed RNA-seq analytics platform designed to identify candidate imaging biomarkers and therapeutic targets associated with chemotherapy induced toxicities. The platform integrates large-scale transcriptomic datasets …

The Ethical Imperative Of Public Health Institutions To Protect The Reproductive Autonomy Of Vulnerable Populations, Kennethea Wilson

Electronic Theses and Dissertations

This dissertation establishes the ethical responsibility of public health institutions to safeguard reproductive autonomy, especially among vulnerable populations. While reproductive decision-making is traditionally framed within individual clinical encounters, this work contends that reproductive autonomy is fundamentally a matter of public health ethics. Socioecological determinants, including social, legal, environmental, and structural factors, often constrain individuals’ ability to make meaningful reproductive choices, leading to preventable harm.

Reproductive autonomy is defined as the capacity to make informed decisions about whether and when to conceive, as well as how to parent. The dissertation critiques the sufficiency of clinical ethics frameworks, such as informed consent …

Clemson Commencement Program, May 2026, Clemson University

Clemson Commencement Programs

No abstract provided.

Systemic Α₂-Agonist Use And Lower Hazard Of Glaucoma Compared With Β-Blockers: A Cohort Study, Ibrahim Abboud, Amin Z. Khudari, Abdelaziz Abdelaal, Amr Almobayed, Subhi J. Al'aref, Jonathan S. Myers, Richard K. Lee, Abdelrahman M. Elhusseiny

Wills Eye Hospital Papers

OBJECTIVE: Systemic antihypertensive medications may influence glaucoma-related outcomes through intraocular pressure-dependent and vascular mechanisms. While topical α₂-agonists are established glaucoma therapies, the association between systemic α₂-agonists and glaucoma hazard remains unexamined; we compared their hazard with systemic β-blockers in adults with hypertension.

METHODS AND ANALYSIS: We conducted a multicentre retrospective cohort study using deidentified electronic health records. Adults aged ≥40 years with hypertension and chronic exposure to systemic α₂-agonists or β-blockers were included. Patients with pre-existing ocular hypertension (OHT), primary open-angle glaucoma (POAG), concomitant comparator use, or inadequate ophthalmic follow-up were excluded. We balanced cohorts using propensity score matching (PSM) …

Illness Perception, Depression, And Anxiety Among Middle-Aged Adults With End-Stage Chronic Kidney Disease, Zioleyda Soto

Walden Dissertations and Doctoral Studies

No abstract provided.

Machine Learning-Based Prediction Of Proximal Junctional Pathology After Adult Spinal Deformity Surgery: A Systematic Review And Diagnostic Test Accuracy Meta-Analysis, Shaan Patel, Shiva A. Nischal, Yi Hein Chai, Kush M. Kale, Kevin Hines, Joshua Pelta-Heller, Jack Jallo, James S. Harrop, Srinivas K. Prasad

Department of Neurosurgery Faculty Papers

BACKGROUND: Proximal junctional kyphosis (PJK) and failure (PJF) remain challenging and incompletely predictable adverse event following adult spinal deformity (ASD) surgery. Machine learning (ML) models have been proposed to improve risk stratification, but performance varies and clinical applicability remains uncertain. A systematic review and diagnostic test accuracy meta-analysis was performed to synthesize the predictive performance of ML-based models for proximal junctional pathology after ASD surgery.

METHODS: PubMed, Embase, and CENTRAL were searched from inception to February 2026. Studies developing or validating ML models predicting PJK or PJF following ASD surgery were included. Diagnostic performance was synthesized using random-effects models, pooling …

Uncovering Cytoskeletal Length Control From Growth Trajectories Using Sparse Dynamical Modeling, Carson Hearn

Theses

Understanding the governing equations of biological filament dynamics is essential for predicting cellular behavior, yet these equations are often difficult or impossible to derive directly from first principles. This thesis investigates the use of Sparse Identification of Nonlinear Dynamics (SINDy) as a unified, data-driven framework for discovering, validating, and refining governing equations from both simulated and experimental data. Focusing on biological filament processes, including growth, disassembly, and severing, this work is designed not only to apply SINDy, but to systematically demonstrate that it is a reliable and generalizable tool for modeling complex biophysical systems. To establish this, SINDy is first …

Inside The World Of Probation Officers: Challenges, Perspectives, And Purpose, Achilles A.C. Beumel

Honors Theses

In the United States, probation is the most commonly imposed criminal sentence, necessitating an abundance of probation officers (POs) to serve the system. Given high rates of failed reentry in tandem with high rates of recidivism, there have been calls for a reevaluation of post-conviction supervision systems and strategies, including the PO. The PO is the final form of assistance provided by the criminal justice system to those facing reentry and can heavily impact a client’s likelihood of recidivism. Despite years of research and attempted reform, more studies are still needed to determine strategies for successful reentry outcomes. This study …

Listen To Your Parents: An Exploration Into Why Mississippi Foster Parents Enter, Stay In, And Exit The System, Howell D. Jenkins Iii

Honors Theses

Like many states across the country, Mississippi’s foster care system has faced a shrinking pool of foster parents to care for the state’s most vulnerable children. When states do not have adequate numbers of foster parents, children are susceptible to negative outcomes such as developmental delays, broken attachments with adults, and extended stays in the system. This thesis seeks to understand what motivates individuals to become foster parents, how they experience the system, and what pressures influence their decision to remain fostering or close their doors. To place this research within the appropriate contexts, the thesis draws on literature from …

Ectomycorrhizal Fungal Identity Strongly Influences Soil Properties Relative To Pine Presence And Soil History In A Pine–Eucalyptus System, Braedan Watters

Honors Theses

Invasive Pinus radiata has increasingly spread into native ecosystems in the Southern Hemisphere, including Eucalyptus forests in Australia, where it forms novel hybrid forest systems in which invasive and native tree species coexist. The success of these invasions is closely tied to ectomycorrhizal fungi (EMF) such as Rhizopogon spp., yet the relative roles of pines versus their fungal symbionts in altering soil properties remain poorly understood. This study investigated the independent and interactive effects of soil history (Pinus or Eucalyptus), EMF identity, and pine presence on soil properties using a controlled factorial experiment. Soil from beneath either Pinus …

Beyond The Bug: How The Covid-19 Pandemic Exposed Longstanding Systemic Failures In The United States Workforce And Economy, Abbey M. Markley

Honors Theses

The purpose of this thesis is to investigate and discuss how longstanding systemic failures in the United States exacerbated the effects the COVID-19 pandemic had on the American economy, essential healthcare workers, and overall public trust in institutions. A review of the existing literature surrounding this topic and the subsequent results of various studies were used to compose this thesis. The United States has a painful lack of worker protections and tends to view members of its workforce as expendable, even in times such as pandemic when they are deemed essential. Healthcare workers in particular faced increasing threats to their …

Biochemical Characterization Of Luciferase In Omphalotus Olearius, James H. Martin

Honors Theses

The overall goal of this thesis was to investigate the genetic basis of bioluminescence in Omphalotus olearius, a bioluminescent mushroom. The project initially focused on growing fungal cultures under controlled laboratory conditions and using molecular techniques such as DNA extraction, PCR, and gel electrophoresis to identify the organism and isolate the gene responsible for light production. The main objective was to insert this gene into a bacterial system to confirm its function through observable bioluminescence. However, repeated difficulties in maintaining viable fungal cultures and errors in molecular procedures resulted in inconclusive results, preventing successful gene identification. Due to these …

Determining The Relatedness Of Simian Varicella Virus Strains Using Polymerase Chain Reactions And Delta Herpesvirus-Dervied Primers, Ellyn M. Waits

Honors Theses

This study examines genetic variation among strains of Simian Varicella Virus (SVV) using genomic analysis. The primary goal of this experiment was to observe potential genomic differences among the Liverpool vervet virus (LVV), the Tsukuba herpesvirus, and the Delta herpesvirus (DHV) strains using primer sets developed from the fully sequenced DHV strain. SVV strains were initially cultivated in Vero cell cultures to begin viral propagation. Viral proliferation in these cell cultures enables DNA isolation via standard purification methods. The extracted viral DNA is subjected to polymerase chain reaction (PCR) amplification targeting specific regions of open reading frames (ORFs) in the …

Antibiotic Resistance Patterns In Bacterial Isolates From Mississippi Gulf Coastal Environments, Lawler F. Horn

Honors Theses

Coastal environments host diverse microbial communities that play essential ecological roles but may also serve as reservoirs for antibiotic-resistant bacteria. This study investigated patterns of antibiotic resistance in microbial isolates collected from public beaches along the Mississippi Gulf Coast. A total of 143 bacterial isolates exhibited growth and were included in antibiotic susceptibility screening. High levels of antibiotic resistance were observed, with 137 of 143 isolates showing growth on vancomycin, 124 on amoxicillin, and 102 on erythromycin. Resistance to kanamycin (19/143 isolates) and tetracycline (33/143) was less common. Multidrug resistance was widespread, with 101 isolates (70.6%) resistant to three or …

Belonging, Participation, And Student Success: Evaluating The Academic Impact Of The Biology Mentor Program At The University Of Mississippi, Cole B. Davidson

Honors Theses

This thesis examines whether students’ sense of belonging within the biology department and their participation in the University of Mississippi Biology Mentor Program are associated with success in introductory biology. The project used de-identified departmental survey data and program records collected across multiple semesters in the broader archive from fall 2020 through spring 2025. For the final analyses, course outcome records, mentor attendance records, and survey based belonging records were merged by student code and semester. After removing nonbinary outcome labels and retaining cases with usable belonging data, the analytic sample included 4,299 student-semester records. The primary outcome was a …

Synthesis Of Novel Tetrafluorinated Alcohols Through The Dimerization Of Difluoromethyl Ketones For Use In Drug Development, Abigail A. Ryan

Honors Theses

As the most electronegative element, fluorine has unique applications and properties. The carbon-fluorine bond is known to be one of the strongest bonds in organic chemistry. As a result of fluorine’s high C–F bond strength, fluorine chemistry has become an interdisciplinary field of chemistry, pharmacy, physics, geology, and ecology. In pharmaceuticals for example, current estimates indicate that about 15–20% of FDA approved small-molecule drugs include at least one fluorine atom. The incorporation of fluorine atoms into organic molecules has become a powerful strategy in modern drug development, as fluorination can enhance metabolic stability, lipophilicity, and biological activity. Despite these advantages, …

Celiac Plexus Radiosurgery For Retroperitoneal Pain In Advanced Cancer: A Pre-Specified Secondary Analysis Of Health-Related Quality Of Life In A Phase Ii Single-Arm Trial, Aisling Barry, Ronen Fluss, Laura Dawson, David Hausner, Michael Buckstein, Talia Golin, Laurence Freedman, Marcin Miszczyk, Dayssy Diazpardo, Artur Aguiar, Dror Limon, Raphael Pfeffer, Moaz Ben-Ayun, Liat Hammer, Ziv Symon, Ofir Morag, Gali Jacobson, Adam Dicker, Jerzy Wydmanski, Camilla Zimmermann, Yaacov Lawrence

Department of Radiation Oncology Faculty Papers

BACKGROUND: Retroperitoneal pain syndrome seen in pancreatic cancer is a major clinical challenge. Celiac plexus radiosurgery, a new palliative technique for retroperitoneal pain syndrome, decreased pain levels in a phase II study. Here Health-Related Quality of Life (HRQOL) outcomes are reported.

METHODS: Evaluable patients, who were enrolled between January 2018 and December 2021, in an international single-arm Phase II ethics-approved study (NCT03323489), were included. The pre-specified secondary endpoint-change in HRQOL from baseline to 3- and 6-weeks post-treatment, was measured by the Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) version 4 questionnaire. Mean change was deemed clinically significant (CS) if …

Functionalized Nanodiamonds As Binding Platforms For Single-Stranded Dna, Mallory A. Chapman

Honors Theses

Nanodiamonds (NDs) offer a promising platform for biomolecular applications due to their stability, biocompatibility, and three-dimensional structure. This study focused on developing a nanodiamond–DNA complex in which streptavidin-functionalized NDs would form a protective shell around biotinylated single-stranded DNA (ssDNA), creating a core–shell system like an “M&M” candy with DNA at the center and a protective coating on the outside. DNA has many uses in nanotechnology, including DNA origami, nanomachines, and drug delivery systems, but its degradation limits its practical use, making protective strategies essential.

ND–DNA conjugates were prepared using biotin–streptavidin interactions and analyzed using gel electrophoresis. Initial separation on agarose …

Community Composition Of Antibiotic-Resistant Bacteria On The Mississippi Gulf Coast, Marisa Martin, Colin Jackson

Honors Theses

The Mississippi Gulf Coast is an important resource for transportation, economic development, and recreation. Given its economic and cultural importance, it is crucial to maintain clean and safe conditions along the coast for public health, but other than routine beach monitoring, few studies have examined microbial contamination of coastal waters in this region. This study aimed to determine the quantity, composition, and distribution of bacteria resistant to six different antibiotics (Vancomycin, Kanamycin, Tetracycline, Ciprofloxacin, Erythromycin, or Amoxicillin) in seawater at seven public beaches along the Mississippi Gulf Coast. No bacteria resistant to Ciprofloxacin were detected, and bacteria resistant to Kanamycin …

Lifestyle And Activity Patterns Of The Classic Period Maya From Chac Balam And San Juan, Ambergris Caye, Belize, Abigail L. Hornbeck

Honors Theses

Bioarchaeological research often uses skeletal remains to reconstruct patterns of activity and labor in past populations. This study examines potential sex-based differences in long bone morphology among individuals from the Classic Maya sites of Chac Balam and San Juan on Ambergris Caye, Belize. These coastal communities participated in maritime trade networks, and daily activities such as cargo transport, canoe travel, and fishing may have placed distinctive mechanical stresses on the skeleton. The goal of this study was to evaluate whether measurable differences in bone structure between males and females reflect differences in habitual activity patterns.

Two complementary methods were used …