Digital Commons Network^™

Understanding Husbands Who Live With A Spouse Who Abuses Substances: A Phenomenological Study, Starla Rachelle Huckeba

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to describe the lived experiences of Christian non-addicted husbands who are married to a substance-abusing wife in Texas. A thorough review of existing literature indicated that previous research has focused on female non-addicted family members. From this, a gap was identified, and the central research question was developed: How did the Christian non-addicted husband describe the personal effect of living with a substance-abusing wife? Family systems theory, attachment theory, and attachment to God theory guided this study. The sample included 12 husbands whose wives abuse substances. The data collection consisted of the completion …

A Transcendental Phenomenological Study Of African American Adults Who Self-Identify As Christians Serving As Caregivers For Their Parents Or Family In The Southeastern United States, Margaret J. Lee

Doctoral Dissertations and Projects

The purpose of this qualitative, transcendental-phenomenological study was to explore the lived experiences of African American adult children who self-identify as Christians and serve as caregivers for their parents or family members in the southeastern United States. Despite the prevalence of caregiving within African American families, research typically does not capture the unique cultural and spiritual contexts that shape these experiences. The theories guiding this study are Bowen's family systems theory (Bowen, 1978) and the Afrocentric Perspective. These theories examine family dynamics and cultural expectations. This study sought to understand how faith, cultural values, and familial dynamics shape caregivers' experiences, …

Exploring The Lived Experiences Of Spouses Of Veterans With Ptsd And Nightmares In Coastal Georgia, Heather Evans

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to understand the lived experiences of spouses of veterans diagnosed with posttraumatic stress disorder (PTSD) with recurring nightmares in coastal Georgia. Since the experience of the spouse of a veteran is a unique experience, the theories that guided this study were Bowen’s family systems theory and Lazarus and Folkman’s stress theory. These theories guided this study in comprehending the complexities of this role and the family dynamics and stress of a spouse of a veteran with PTSD and nightmares. Thematic analysis was used in this study to analyze the data. The literature on …

Movement-Stabilized Three-Dimensional Optical Recordings Of Membrane Potential Changes And Calcium Dynamics In Hippocampal Ca1 Dendrites, Kevin C Gonzalez, Satoshi Terada, Asako Noguchi, George N Zakka, Cliodhna O'Toole, Giuliana Bilbao, Luke Reynolds, Anna Jász, Borbála Kertész, Zoltán Szadai, Alissa Shen, François St-Pierre, Franck Polleux, Attila Losonczy, Balázs Rózsa

Faculty, Staff and Students Publications

Local dendritic computations are thought to critically influence neuronal signaling and plasticity yet remain largely unexplored in vivo due to challenges in stably imaging small structures at ultrafast timescales. We developed a 3D real-time motion correction platform for movement-stabilized, ultrafast two-photon voltage imaging. By co-labeling CA1 pyramidal neurons with voltage and calcium indicators, we simultaneously measured somato-dendritic and electro-calcium coupling at multiple dendritic sites. We characterized isolated dendritic spikes and distance-dependent backpropagation of naturally occurring and photostimulation-evoked bursts and single spikes. We found that bursts backpropagated more reliably than single spikes, validated that somato-dendritic coupling decreases with distance from soma, …

Phkg2 Confers Resistance Of Escc To Cisplatin And Enhances Cxcl8-Dependent Immunosuppression To Exacerbate Tumorigenesis, Jiayan Wu, Chengrui Zhong, Haosheng Zheng, Fei Qin, Xianyu Qin, Yuzhen Zheng, Junguo Chen, Gengfeng Wang, Bozhu Jian, Zui Liu, Xingping Yang, Chao Cheng, Guolin Li, Hongying Liao

Faculty, Staff and Students Publications

Cisplatin (DDP)-based chemotherapy serves as a foundational cornerstone in the clinical management of esophageal squamous cell carcinoma (ESCC). However, intrinsic or acquired resistance to DDP persists as a significant clinical challenge, severely undermining therapeutic efficacy and contributing to unfavorable patient prognoses. Through functional screening with a CRISPR/Cas9 knockout library, transcriptomic profiling of cisplatin-resistant cell lines and clinical specimens, and in vitro/in vivo validation assays, we identified PHKG2 as a key mediator of cisplatin resistance in ESCC. Mechanistically, PHKG2-mediated cisplatin resistance is driven by the phosphorylation of IGF2BP3 at residues T225 and T306. This post-translational modification enhances IGF2BP3 phase separation, thereby …

Comparative Hematological And Biochemical Alterations Associated With Gram-Negative Bacterial Infections Of Lower Urinary Tract In Dogs And Cats, Mohamed Alasmar, Maged El-Ashker, Mohammed Albaloushi, Mayyadah Alkuwayti, Mohamed Marzok

The Thai Journal of Veterinary Medicine

The aim of this study was to investigate hematological and biochemical alterations associated with gram-negative bacterial lower urinary tract infections (UTIs) in dogs and cats. For this purpose, 56 dogs and 36 cats were examined between October 2022 and May 2023. Twenty-eight dogs and twenty-two cats with clinical signs of lower UTIs were confirmed using ultrasonography, urinalysis, hematobiochemical analysis, and molecular identification of recovered pathogen. In dogs, UTIs were significantly associated with pyuria (82%), crystalluria (85.7%), and proteinuria. There was also significant decrease in total protein and globulin levels compared to those in the control. A significant increase in BUN, …

Hantaviruses As Priority Zoonotic Diseases: A Comprehensive Review, Wimbuh Tri Widodo, Aswin Rafif Khairullah, Rahmania Ambarika, Widoretno Widoretno, Masri Sembiring Maha, Abdul Hadi Furqoni, Lisa Andriani Lienggonegoro, Bima Putra Pratama, M. Hasinuddin, Zakkiyatus Zainiyah, Eny Susanti, Mufarika Mufarika, Luluk Hermawati, Alvina Setiawardani, Syahputra Wibowo, Arif Nur Muhammad Ansori

The Thai Journal of Veterinary Medicine

Hantaviruses are zoonotic agents that play a significant role in global public health, primarily due to their ability to cause two highly severe clinical syndromes: Hemorrhagic Fever with Renal Syndrome (HFRS), which is predominant in Eurasia, and Hantavirus Cardiopulmonary Syndrome (HCPS/HPS), which is primarily found in the Americas. Although long recognized, the complex interactions between the virus, its rodent reservoir, and environmental factors make hantaviruses still a relevant epidemiological threat today. This review aims to provide a comprehensive overview of their virological characteristics, epidemiological patterns, pathogenesis mechanisms, risk factors, diagnostic methods, therapeutic options, prevention strategies, and the latest developments in …

Hak Waris Anak Luar Kawin Yang Lahir Dari Perkawinan Campuran Menurut Kuhperdata Dan Uu No.1 Tahun 1974 Tentang Perkawinan, Wijayanto Setiawan

Jurnal Hukum & Pembangunan

Abstract

Pengelolaan Konflik Pemanfaatan Sumber Daya Hutan Dalam Mewujudkan Hak Masyarakat Lokal, Agus Surono

Jurnal Hukum & Pembangunan

Abstract

Turn Your Expertise Into Income Through Goal, Russell Stein

Staff Professional Development Week

Russell Stein introduces staff to GOAL and the Learning and Training Center as a simple way to turn their knowledge into short, online learning modules. The main idea: staff already have valuable knowledge, and this workshop shows how to share it in a way that helps others and may also bring in income.

Participants will learn how GOAL supports lifelong learning and may offer ways to earn money in the future. The workshop will also introduce a flexible profit sharing model and explain how Instructor Design Services makes things easier. Staff do not need to build a full course. They …

Isolation Of Essential Oils From Oregano Leaves Via Steam Distillation And Extraction, Alyssa Brasko, Madison Fauntleroy, Sophia Bordone

Discovery Day - Daytona Beach

Organum vulgare, also known as Oregano, is a fragrant herb in the mint family widely used in culinary and medical applications. The essential oil of oregano contains various compounds, with carvacrol and thymol being the primary constituents responsible for the herb’s distinctive aroma and antimicrobial properties. Carvacrol, a chemical compound found in oregano oils, has a molecular formula of C₁₀H₁₄O, with carvacrol presenting a phenolic structure that contributes to its biological activity. Additionally, the compound has three double bonds giving the compound four units of unsaturation. Due to its properties, oregano oil has historically been used …

Genetic Association Of Alzheimer's Markers, Annelise Beauchamp

Discovery Day - Daytona Beach

This project will investigate the relationship between genetic variants and susceptibility to Late Onset Alzheimer’s. By leveraging publicly available datasets that show statistically significant associations between genetic markers and disease occurrence, this project will contribute to a deeper understanding of how specific genetic factors contribute to a disease.

Tardigrade Bio-Exploration Reproduction Research Satellite (Tbearr), Joshua Lozano

Discovery Day - Daytona Beach

The Tardigrade Bio-ExplorAtion Reproduction Research Satellite (tBEARR) is a 3U CubeSat mission under development by the Embry-Riddle Orbital Research Association (ERORA), an undergraduate research club at Embry-Riddle Aeronautical University (ERAU) in Daytona Beach, FL. The mission aims to launch four separate cultures of tardigrades aboard a 3U CubeSat to Low-Earth Orbit (LEO) to study the effects of UV and cosmic radiation on their genetics and cell composition, which may, in turn, affect their reproduction cycle. Tardigrades are microorganisms renowned for their remarkable resilience to extreme conditions, including extreme temperatures, pressures, low-oxygen environments, and extended periods without food or water. Research …

Bio-Inspired Cybersecurity: Adapting Immune System Strategies For Threat Detection In Autonomous Aerospace Navigation, Leia Spaniak

Discovery Day - Daytona Beach

The purpose of this research is to investigate how a biological immune-based response can be employed to create a self-evolving cybersecurity framework for aerospace navigation systems. Specifically, as part of Project SENTINEL, this research identifies key members of dendritic cells (DCs) to understand their mechanisms for detecting diverse varieties of foreign invaders, from malignant bacteria to viral infections. The multi-layered approach of Pathogen Recognition Receptors (PRRs) in threat detection contributes to the innate immune system by employing a diverse array of generalized and specialized receptors, such as varieties of Toll-Like Receptors (TLRs) and Nod-Like Receptors (NLRs), which can trigger inflammatory …

Simulated Microgravity Effects On Escherichia Coli Mg1566 Ability To Form Biofilms And Its Potential Implications On Virulence, Tyler Jenkins

Discovery Day - Daytona Beach

Microorganisms are an integral part of any biological system’s performance, and researching the different tendencies of bacterial strains give scientists a more structured idea of how to work with them in specific applications. Bacterial research consists of studying antibiotic resistance, virulence, differential gene expression in extreme environments. Studies using microgravity analogs have shown that different strains have implications for astronaut performance and life support systems, and further research must be devoted to understanding the different mechanisms facilitating these adaptations and mitigating the risks these bacteria pose to the success of space missions. This experiment focuses on studying the phenotypes of …

Isolation Of Linalool And Linalyl Acetate From Lavender Via Steam Distillation, Leah Robinson, Grant Erlinder

Discovery Day - Daytona Beach

Linalool and linalyl acetate are naturally occurring monoterpenes found in lavender, they are known for their distinct aroma and biological properties. Linalool has the chemical formula of C₁₀H₁₈O and is a monoterpene alcohol, while linalyl acetate has the chemical formula of C₁₂H₂₀O₂ and is linalool’s acetate ester. These compounds have been widely studied for their anti-inflammatory properties, studies have indicated that these compounds influence inflammatory pathways, decrease inflammatory-associated molecules, and enhance the production of protective proteins. Linalool exhibits anti-inflammatory properties by regulating cytokine production and reducing oxidative stress, whereas linalyl acetate acts as a precursor to linalool, providing continuous anti-inflammatory …

Galactic Cosmic Radiation And Microgravity-Induced Changes Of Murine T Cell [email protected], Astrid Senko, Graema Grainger, Angela Cebula

Discovery Day - Daytona Beach

Astronauts on long-duration space missions are exposed to significant environmental stressors, including microgravity and various forms of ionizing radiation. These stressors can cause physiological and cellular adaptations which can lead to significant implications on immune function. Understanding how these spaceflight conditions alter immune response is essential, particularly in the context of immune cell structure and function. This study examines whether spaceflight stressors alter T cell phenotypes in mice which can result in disrupted immune homeostasis, resulting in the potential for increased susceptibility to infections and persistent inflammation. To simulate spaceflight conditions, male and female, 24-week old, C57BL/6J mice were exposed …

Aging Popular Exoplanet Host Stars; A Bayesian Analysis Of Stellar Evolution, Grace Henry

Discovery Day - Daytona Beach

This study uses BASE-9, a software tool designed for stellar age analysis, to investigate the ages of exoplanet host stars. We found the stars through a query of the NASA Exoplanet Archive based on the orbital distance of their exoplanets. The habitable zone (HZ) approach we use [2] analyzes the effective temperature and luminosity of stars between 2600 K to 7200 K. Single star systems with that effective temperature range and planets in the calculated HZ were added to our host star candidate set. From there, we used the BASE-9 (Bayesian Analysis of Stellar Evolution) software suite to derive ages …

Project Cor, Bret Grebiner

Discovery Day - Daytona Beach

Yale Medicine Online reports that 3,500 individuals in the United States currently await heart transplants, many relying on artificial hearts that offer limited longevity and prohibitive costs. A reliable, affordable artificial heart could significantly improve quality of life and accessibility. This project evaluates whether a compliant silicone artificial heart can generate pressures comparable to physiological heart function, validating its potential as an affordable and durable alternative. Planned developments include incorporating conductive filament to enable controlled chamber contractions, closely replicating natural cardiac activity. Preliminary results show promise in affordability and performance. Successful integration of conductive filaments for contraction could further improve …

Magnetic Actuation Chamber System, Reghan Schafer, Brian Davies Ii, Jonah D. Reed

Discovery Day - Daytona Beach

The Magnetic Actuation Chamber System (MACS) is an innovative solution designed to enhance the cultivation of cells and tissues under simulated microgravity conditions using a 3D clinostat. By integrating a magnetic actuator with a microfluidic organ-on-chip platform, the system facilitates precise mechanical stimuli for tissue engineering and disease modeling. Key upgrades, including a pneumatic piston system, Raspberry Pi 4-based processing, and enhanced nutrient delivery through microfluidic pumps, significantly improve reliability, data collection, and adaptability. The system’s modular design ensures flexibility for future modifications. Initial results demonstrate the potential of MACS to replicate natural cellular environments, with plans to study heart …

Joyful Literacy Experiences: Insights From The Pei In Multicultural Ya Literature, S. Rebecca Leigh, Taraneh Matloob Haghanikar, Danielle Alexander, Yujie Mao, Kim Stein, Maria Mendola, Xunmei Luo, Quigxian Wang, Yonghong Li

Michigan Reading Journal

The primary focus of this qualitative study was to determine how we could apply the theory of emotion and transactional reader response theory to the experience of coding and analyzing emotion in multicultural young adult literature. Seven graduate students in a doctoral class in the Midwest participated in the study for one academic semester, including their instructor and another faculty member from a different Midwestern university. Data included coding and analysis of eight Coretta Scott King medal and honor-winning novels and the Protagonist Emotion Inventory (PEI). Chapters were coded for eight basic emotions and the constant comparative method (Corbin & …

From Talk To Science Literacy: Using Structured Student Talk To Support Newcomer Multilingual Learners In High School, Matthew W. De Boer, Rui Niu-Cooper

Michigan Reading Journal

Newcomer multilingual learners (MLs) often experience significant barriers to oral participation in secondary classrooms, despite the central role of talk in language development, academic learning, and community belonging. Research indicates that while comprehension skills may continue to develop, opportunities for structured oral expression are frequently limited, particularly in teacher-led instructional settings. This article examines how intentional Structured Student Talk (SST) routines can support newcomer MLs in transitioning from classroom silence to meaningful participation. Drawing on interactionist theories of language development, cognitive load theory, and affective filter research, the article argues that oral language must be explicitly scaffolded within content instruction …

Full Issue: Volume 58, No. 3

Michigan Reading Journal

No abstract provided.

Explainable Tree-Based Ensemble Models For Diabetes Prediction Using Shap, Maan Y Anad Alsaleem, Omar Shakir Hasan, Yahya Albugg

AUIQ Technical Engineering Science

Due to the generally unqualified nature of prediction data and the difficulty of interpreting predictions, predicting diabetes remains a significant hurdle in the adoption of machine learning within the medical domain. In this study, several tree-based machine learning techniques (LightGBM, XGBoost, CatBoost, and Gradient Boosting) were applied to predict diabetes using the 2015 BRFSS dataset, while two ensemble methods (soft voting and stacking) were employed to improve predictive accuracy. The performance analysis of the individual models and ensemble approaches indicates that CatBoost achieved the highest accuracy among the single classifiers (0.871), with an F1-score of 0.871 and a ROC–AUC of …

Chronotropic Response To Intratracheal Versus Intravenous Atropine In Anesthetized Adult Patients: A Randomized Controlled Trial, Ammar H. Mahdi, Majid Alhamaidah, Myasar J. Mohammed, Hussein Ali Hussein, Hussein Alkhfaji

AUIQ Complementary Biological System

Atropine is a commonly used anticholinergic agent in anesthetic practice, administered primarily to counteract bradycardia. Rapid treatment of intraoperative bradycardia is clinically critical, as delays may lead to hemodynamic compromise. This study aimed to compare the onset, magnitude, and duration of the chronotropic response to atropine administered via the intravenous (IV) versus intratracheal (IT) route in anesthetized adult patients. A prospective, single-blind, randomized controlled study was conducted on 60 adult patients classified as American Society of Anesthesiologists (ASA) physical status I-II, scheduled for elective peripheral surgery under general anesthesia. Patients were randomly allocated into three equal groups (n = 20 …

Intent Gravity Engines, Johny Manuel-Devadoss, Joanna Johnson, Jayden Jack Johnson

Defensive Publications Series

Contemporary recommendation architectures optimize short-horizon behavioral objectives such as click-through rate, retention, conversion probability, watch-time maximization, and engagement persistence. While these systems achieve high efficiency in immediate interaction optimization, they systematically fail to model longitudinal human development, identity continuity, aspiration stabilization, and temporally coherent cognitive evolution. Existing recommender systems operate under an implicit assumption that preferences are stationary or slowly drifting latent variables inferable from interaction sequences. This assumption becomes increasingly invalid in high-dimensional socio-cognitive environments where users are not static consumers but dynamically evolving agents whose identities emerge through recursive interactions between cognition, social exposure, emotional state transitions, epistemic …

Experimental And Numerical Analysis Of Mechanical Properties Of Uhmwpe Nanocomposite Reinforced With Nano-Hydroxyapatite, Heshw A. Hassan, Diyar O. Kaka

Engineering and Technology Journal

Recently the polymer nanocomposites have shown significant development, enabling substantial improvements in the performance of conventional polymers that reflect large influences on the products and industry. Ultra-high molecular weight polyethylene (UHMWPE) is widely employed in biomedical and structural applications, their mechanical properties can be tailored through the incorporation of nanoscale fillers. In this study, nano-hydroxyapatite (nHA) particles were incorporated into UHMWPE at reinforcement loadings of 0.5, 1.0, 3.0, and 5.0% content experimentally, and different volume fraction numerically to evaluate their effect on the material's mechanical behavior. A Representative Volume Element (RVE) based on finite element analysis (FEA) was developed to …

Enhanced No₂ Gas Sensing Using Silver-Doped Cadmium Telluride Nanocrystalline Thin Films, Tunis Balasim Hassan

Karbala International Journal of Modern Science

Nitrogen dioxide (NO₂) is a toxic pollutant that necessitates sensitive and reliable monitoring systems. Conventional gas sensors often lack adequate responsiveness and fast recovery under changing conditions and therefore create a need for semiconductors with enhanced performance, especially at high industrial temperatures (around 250 °C). The study therefore aims to synthesis and evaluate silver-doped cadmium telluride (Ag:CdTe) thin films as NO₂ gas sensors. Pure CdTe and Ag:CdTe with silver concentrations of 5, 10, and 15 wt% were prepared by a co-precipitation process. XRD verified cubic symmetry with a progressive fall in crystallite size (6.67 nm to 5.46 nm at 15 …

Design Considerations For Hypertension Chronotherapy Trials: Insights From Experience And Modelling, Olivia Walch, Amy Rogers, Yitong P. Huang, Marc D. Ruben, Kenneth A. Dyar, Robert W. V. Flynn, Isla S. Mackenzie, Roberto Manfredini, Francesco P. Cappuccio, Filippo Pigazzani

Mathematics Sciences: Faculty Publications

Chronotherapy aims to maximise treatment efficacy while minimising side effects by scheduling treatment according to personal biological rhythms. In recent years, randomised clinical trials (RCTs) have been conducted to evaluate whether scheduled blood pressure interventions can improve patient outcomes. However, reports of time-of-day effects have attracted rebuttals and engendered methodological debate. A perfectly controlled chronotherapy trial (i.e., a trial that assesses the effect of assigning time of intervention) will never be feasible in the real world; yet some factors may be more critical to consider and control for than others. To advance the conversation about how best to evaluate the …

Transforming Power: The Adaptation Of Customary Authorities In Aceh's Forest Governance, Ikhwan Rahmatika Latif, Akmal Saputra, Masrizal Masrizal, Nodi Marefanda, Herdin Arie Saputra

Forest and Society

This article examines the transformation of customary authority in forest governance in Aceh, Indonesia, moving beyond the conventional narrative of decline toward a more nuanced view of power as relational and negotiated. Utilizing the frameworks of political ecology and legal pluralism, the research examines how indigenous institutions adapt to evolving governance structures, spanning from the Sultanate era to centralized state authority and into the post-conflict special autonomy framework. This research employs a qualitative approach, combining literature analysis, legal review, and case-based insights from several regions in Aceh to examine the evolving relationship between customary institutions and forest governance. The findings …