Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2026

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 601 - 630 of 18144

Full-Text Articles in Entire DC Network

Patterns Of Autonomous And Conditional Neural Specification For The Brain And Ventral Nerve Cord In Annelida, Nicole B. Webster, Johnny A. Davila-Sandoval, Allan M. Carrillo-Baltodano, Skyler Duda, B. Duygu Özpolat, Neva P. Meyer Sep 2026

Patterns Of Autonomous And Conditional Neural Specification For The Brain And Ventral Nerve Cord In Annelida, Nicole B. Webster, Johnny A. Davila-Sandoval, Allan M. Carrillo-Baltodano, Skyler Duda, B. Duygu Özpolat, Neva P. Meyer

Biology

Evolution of central nervous systems is a long-debated topic. Similar mechanisms of conditional neural specification linked to dorsal-ventral (D–V) axis formation have been used to support homology across several taxa. We tested for autonomous versus conditional neural specification in two distantly related annelids, Capitella teleta and Platynereis dumerilii, using blastomere isolations and ablations. Our results demonstrate autonomous specification of anterior neural tissue in isolated first-quartet (1q) micromeres for both annelids. In both annelids, partial larvae derived from isolation of the somatoblast, micromere 2d, also resulted in the formation of trunk neural tissue (ventral nerve cord or VNC), suggesting that this …


Gene-Environment Interactions In Cardiovascular Aging: Volunteering, Polygenic Risk, And Biomarker Change In European And African Ancestry Populations, Seoyoun Kim, Byeongju Ryu, Erin Ware, Koichiro Shiba, Cal J. Halvorsen Sep 2026

Gene-Environment Interactions In Cardiovascular Aging: Volunteering, Polygenic Risk, And Biomarker Change In European And African Ancestry Populations, Seoyoun Kim, Byeongju Ryu, Erin Ware, Koichiro Shiba, Cal J. Halvorsen

Brown School Faculty Publications

Volunteering has been associated with better cardiovascular health, but whether this association varies by genetic susceptibility to cardiovascular disease remains unclear. This study examined associations between volunteering and cardiovascular biomarkers, assessed associations between biomarker-specific polygenic scores (PGSs) and these outcomes, and tested whether polygenic risk moderated volunteering–biomarker associations among U.S. adults aged 51 years and older.


Methodological Optimization Of Microplastic Visualization For The Comparison Of Eastern Oysters Cultivated In Traditional Plastic Or Novel Non-Plastic Aquaculture Farm Gear, Mikayla Straube Sep 2026

Methodological Optimization Of Microplastic Visualization For The Comparison Of Eastern Oysters Cultivated In Traditional Plastic Or Novel Non-Plastic Aquaculture Farm Gear, Mikayla Straube

All Theses And Dissertations

Microplastics (< 5 mm) are a pervasive physical pollutant. This study was predominately focused on the development and utilization of fluorescence microscopy to locate and identify microplastics and other particles in the presence of a background autofluorescing biogenic precipitate. Oyster digest samples are visualized with fluorescent microscopy using Nile Red (NR). Photobleaching, or concentrated light exposure, of the filters was tested to determine if it can quench the autofluorescence signal. It was found that photobleaching significantly decreased autofluorescence intensity of the biogenic precipitate in emission wavelengths 518, 580, and 670 nm even with the application of NR, while minimally impacting the fluorescence behavior when bound to plastic particles. In application, fluorescence microscopy still yields some gaps in microplastic identification  when compared to Raman spectral results. This methodology was broadly developed to be able to quantify ambient microplastic quantities in farmed oyster samples. The specific level of aquaculture’s contribution to plastic pollution in global waterways is difficult to estimate. The methodology was applied to a local case study that compared microplastic loading in cultured eastern oysters raised in traditional plastic farm gear and novel plastic-free farm gear. Marginal trends in the gear type treatment and microparticles identified across the harvest season were identified, however effect sizes were too weak, and evidence was too inconsistent to currently suggest that gear type and harvest date affect microplastics and other particle quantities g-1 oyster tissue (d.w.).


The People’S Liberation Army In A New Era: Individuals, Ideas, And Influence, Joel Wuthnow, Derek Grossman, Phillip C. Saunders, Andrew Scobell, Andrew N.D. Yang Sep 2026

The People’S Liberation Army In A New Era: Individuals, Ideas, And Influence, Joel Wuthnow, Derek Grossman, Phillip C. Saunders, Andrew Scobell, Andrew N.D. Yang

Books

The People’s Liberation Army in a New Era: Individuals, Ideas, and Influence assesses how China’s military has changed under Xi Jinping and the extent to which those changes reflect his leadership versus longer-term institutional trends. The volume addresses PLA modernization, organizational reform, political control, joint operations, deterrence, artificial intelligence, officer careers and training, Taiwan, China-Russia military exercises, military aid, and overseas security activities. It argues that while Xi has played a major role in shaping the PLA, many developments build on earlier reforms, enduring strategic priorities, and institutional practices.


Academic Symposium Program Sep 2026

Academic Symposium Program

The Inauguration of Joseph C. Hartman (2026)

The Academic Symposium highlights the innovations in scholarship and excellence in teaching that make WNE a place where possibilities take shape.


Hhp 529.01: Advanced Exercise Physiology I, Charles L. Dumke Sep 2026

Hhp 529.01: Advanced Exercise Physiology I, Charles L. Dumke

University of Montana Course Syllabi, 2026-2030

No abstract provided.


Kin 310.01: Strength Training And Conditioning, Andrew C. Berrier Sep 2026

Kin 310.01: Strength Training And Conditioning, Andrew C. Berrier

University of Montana Course Syllabi, 2026-2030

No abstract provided.


Kin 330.01: Motor Learning And Control, Matthew W. Bundle Sep 2026

Kin 330.01: Motor Learning And Control, Matthew W. Bundle

University of Montana Course Syllabi, 2026-2030

No abstract provided.


El Leñador, September 2026, El Leñador Staff Sep 2026

El Leñador, September 2026, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …


Noncoding Rna Transcripts Based Molecular Phenotyping Of Masld And Mash Patients, Frida M. Delgadillo, Karla Perez, Barbara Yang, Subramanian Dhandayuthapani, Murali Yallapu, Subhash C. Chauhan, Enrique I. Ramos, Shrikanth S. Gadad Sep 2026

Noncoding Rna Transcripts Based Molecular Phenotyping Of Masld And Mash Patients, Frida M. Delgadillo, Karla Perez, Barbara Yang, Subramanian Dhandayuthapani, Murali Yallapu, Subhash C. Chauhan, Enrique I. Ramos, Shrikanth S. Gadad

School of Medicine Publications

Background and aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive hepatic metabolic disorder characterized by excessive fat accumulation in hepatocytes. MASLD can advance to metabolic dysfunction-associated steatohepatitis (MASH). These conditions often lead to hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC) if not timely diagnosed and managed; thus, molecular phenotyping of MASLD and MASH conditions is highly desirable. The analyses were performed to identify distinct, differentially expressed genes, particularly noncoding ones, in MASLD and MASH patient samples, thereby expanding diagnostic and therapeutic options.

Methods: We extracted the data from a recent transcriptomic study by Govaere et al. on MASLD …


The Revival Of Honor Killing In Iranian Kurdistan: A Sociological Analysis Of Gender, Land, And Identity, Parviz Sobhani Sep 2026

The Revival Of Honor Killing In Iranian Kurdistan: A Sociological Analysis Of Gender, Land, And Identity, Parviz Sobhani

Dignity: A Journal of Analysis of Exploitation and Violence

Honor is a foundational yet restrictive sociocultural construct in Kurdish society of western Iran. Transgressions of its boundaries, particularly by women, are historically met with violent sanction. Despite processes of modernization, honor killings have re-emerged as a conspicuous phenomenon in Iranian Kurdistan, suggesting an active revival rather than a passive residue of tradition. This study employed a qualitative, interpretive phenomenological approach. The data were collected through semi-structured interviews with 21 social scientists and researchers from January 2022 to February 2024 in Iranian Kurdistan.  A grounded theory framework guided the thematic analysis. Findings reveal a dual symbolic encoding of honor: it …


When Protection Becomes Predation: Militarized Masculinity And Sexual Violence In Northeastern Nigeria, Tosin Osasona Sep 2026

When Protection Becomes Predation: Militarized Masculinity And Sexual Violence In Northeastern Nigeria, Tosin Osasona

Dignity: A Journal of Analysis of Exploitation and Violence

The study investigates the structural and situational drivers of conflict-related sexual violence (CRSV) perpetrated by state security actors in the context of Nigeria’s counterinsurgency campaigns in Borno State. Drawing on militarized masculinity and strain and deprivation theories, and using a qualitative, interpretive research design, the study argues that CRSV is not an isolated or episodic form of deviance by individual soldiers and security personnel but is embedded in routine military–civilian interactions. Advancing an interactionist explanation of CRSV in Nigeria’s Islamist counterinsurgency operations, the study demonstrates that the likelihood of sexual violence increases through the interaction of gendered institutional norms, operational …


Sensation And Perception V3, Todd A. Kahan Sep 2026

Sensation And Perception V3, Todd A. Kahan

Open Educational Resources

Sensation and Perception V3 is an introductory college textbook that explores how we detect and interpret sensory information from the world around us. Covering all five major senses—vision, audition, touch, taste, and smell—the book provides a comprehensive overview of the biological and psychological processes that underlie perception. While all sensory modalities are discussed, the primary emphasis is on vision, tracing the flow of visual information from the moment light strikes the retina through the complex mechanisms that allow us to perceive objects, color, motion, and depth.


The Influence Of Childhood Experiential History On U.S. Vice President Jd Vance’S Personality, Amelia Brower, Aubrey Immelman Sep 2026

The Influence Of Childhood Experiential History On U.S. Vice President Jd Vance’S Personality, Amelia Brower, Aubrey Immelman

Psychology Faculty Publications

This paper presents the results of a developmental causal analysis of the adult personality of U.S. vice president JD Vance, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data relating to Vance’s personality were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5-TR.

The findings of the personality assessment were previously reported in a separate paper. Vance’s primary personality patterns were found to be Dominant/controlling and Ambitious/confident, supplemented by …


A Delayed Siamr Prostate Cancer Model With Vertical Transmission And Treatment: Stability Analysis And Numerical Simulation, Hüseyi̇n Demir, İnci̇ Çi̇li̇ngi̇r Süngü, İbrahi̇m Keles Sep 2026

A Delayed Siamr Prostate Cancer Model With Vertical Transmission And Treatment: Stability Analysis And Numerical Simulation, Hüseyi̇n Demir, İnci̇ Çi̇li̇ngi̇r Süngü, İbrahi̇m Keles

Turkish Journal of Mathematics

​In this paper, we propose and analyse a delayed-compartmental mathematical model of prostate cancer dynamics that incorporates vertical transmission and therapeutic intervention. The population is stratified into five compartments: susceptible (S), infected/virally activated (I), asymptomatic infectious under treatment (A), malignant untreated (M), and recovered (R). A discrete time delay τ > 0 is introduced in the force-of-infection term to model the age-dependent onset of susceptibility in middle-aged adult males. Vertical transmission of viral etiology at a rate qΛ ensures that a fraction of newborns enter the infected compartment directly, rendering the disease persistent regardless of the basic reproduction number R₀. We …


Hyers-Ulam And Hyers-Ulam Rassias Stability Of Caputo Fractional Hahn Difference Equations, Karima Mohamed Oraby, Alaa E. Hamza, Afrah Al-Bossly Sep 2026

Hyers-Ulam And Hyers-Ulam Rassias Stability Of Caputo Fractional Hahn Difference Equations, Karima Mohamed Oraby, Alaa E. Hamza, Afrah Al-Bossly

Turkish Journal of Mathematics

​In this paper, we investigate Hyers–Ulam and Hyers–Ulam–Rassias stability for fractional linear Hahn difference equations of Caputo Type. To the best of our knowledge, this is the first work concerning Hyers–Ulam type stability in the framework of Caputo fractional Hahn difference equations, thereby filling a significant gap in the literature on fractional stability theory. Our approach is based on establishing an equivalence between the fractional Hahn difference initial value problem and a corresponding fractional integral equation, via the Caputo–Hahn inversion formula. These results lay a strong groundwork for analyzing the stability of Hahn fractional systems, which could be useful in …


A Note On The Periodic Orbits Of Wolbachia Spread Dynamics In Mosquito Populations In Periodic Environments, Jose S. Cánovas Sep 2026

A Note On The Periodic Orbits Of Wolbachia Spread Dynamics In Mosquito Populations In Periodic Environments, Jose S. Cánovas

Turkish Journal of Mathematics

We consider the periodic model introduced by B. Zheng and J. Yu, and disprove the conjectures on the number of periodic orbits the model can have. We rebuild the conjecture to prove that for periodic sequences of maps of any period, the number of nonzero periodic trajectories is bounded by two.


Best Practices For Managing Human–Beaver Conflicts In North America: Balancing Ecological Benefits And Human Interests, Alec J. Sundelius, Jerry Altermatt, Doug Brimeyer, Derek J. Broman, Jared Duquette, Cory Mosby, Falyn Owens, Shawn Rossler, David B. Ruid, Brian F. Wakeling, H. Bryant White Sep 2026

Best Practices For Managing Human–Beaver Conflicts In North America: Balancing Ecological Benefits And Human Interests, Alec J. Sundelius, Jerry Altermatt, Doug Brimeyer, Derek J. Broman, Jared Duquette, Cory Mosby, Falyn Owens, Shawn Rossler, David B. Ruid, Brian F. Wakeling, H. Bryant White

Human–Wildlife Interactions Monographs

We explore the complexities of managing beaver (Castor canadensis) conflicts in North America, describing the most common approaches used by natural resource management agencies to address conflicts. We identify specific conflicts caused by beavers, the ecological benefits beavers provide, and the tools commonly used to address conflicts. We discuss regional differences in beaver management strategies, including ecosystem restoration and conflict prevention. We specifically discuss a variety of management practices including public education, land use management, trapping, translocation, exclusion, shooting, dam removal, repellants, and harvest incentive programs; we then review the challenges and benefits of these tools. We discuss …


Hydroxyethyl Starch And Perioperative Complications: A Systematic Review And Meta-Analysis, Daniel I Sessler, Lorenzo Pradelli, Massimiliano Povero, Daniel Chappell, E Wang Sep 2026

Hydroxyethyl Starch And Perioperative Complications: A Systematic Review And Meta-Analysis, Daniel I Sessler, Lorenzo Pradelli, Massimiliano Povero, Daniel Chappell, E Wang

Faculty, Staff and Student Publications

Background: Based on renal injury reported in critically ill and septic patients, the U.S. Food and Drug Administration issued a black box warning regarding hydroxyethyl starch (HES 130/0.4) use in 2013 and expanded the warning to surgical and trauma patients in 2021. Similarly, the European Medicines Agency initiated withdrawal of hydroxyethyl starch in 2022. This study was a new meta-analysis focused on renal injury designed to complement a 2021 meta-analysis of perioperative hydroxyethyl starch use, adding 45 trials and 6,895 patients. The focus was acute kidney injury and preoperative-to-postoperative change in creatinine concentration in surgical patients.

Methods: This study searched …


Synthesis Of Fe-Doped Porous Carbon Catalyst Derived From Coconut Shell Waste Using Ferric Nitrate Nonahydrate (Fe(No3)3.9h2o) As An Iron Precursor, Ilham Lestadi Putra, Sukarni Sukarni, Heru Suryanto Sep 2026

Synthesis Of Fe-Doped Porous Carbon Catalyst Derived From Coconut Shell Waste Using Ferric Nitrate Nonahydrate (Fe(No3)3.9h2o) As An Iron Precursor, Ilham Lestadi Putra, Sukarni Sukarni, Heru Suryanto

Journal of Mechanical Engineering Science and Technology (JMEST)

Renewable energy from lignocellulosic biomass is a promising alternative to fossil fuels. Coconut shell (CS) waste is a favorable precursor for porous carbon due to its high carbon content, abundance, and non-food nature. However, conventional biochar often has limited surface area and catalytic active sites, hindering its effectiveness as a catalyst. While Fe-based modifications are promising, the use of ferric nitrate-assisted activation of coconut-shell-derived porous carbon remains underexplored. This research focused on developing an Fe-doped porous carbon catalyst from CS via ultrasound-assisted impregnation, followed by activation in a tube furnace. CS biochar was produced through pyrolysis at 550 °C and …


September 2026 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean's Office Communication Team Sep 2026

September 2026 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean's Office Communication Team

Library & Learning Newsletters

PDF version of the September 2026 (Volume 5, Issue 1) Library & Learning Newsletter.


Schizophrenia Spectrum Biomarkers Consortium: Establishment Of A Biorepository For The Discovery Of Quantitative Fluid Biomarkers, Mohini Ranganathan, Susanne Jakob, Felecia Cerrato, Lia Urban Spillane, Tarlan S. Daryoush, Sophie Shuster, Katherine Dokholyan, Shaynna Herrera, Brian Koo, Clyde Markowitz, Pojen Deng, Sage Rush, Monica E. Calkins, Scott Troyan, Kosha Ruparel, Ruben C. Gur, Holly Reynolds, Claire Wegel, Matthew B. Johnson, Lauren Hom, Sam Bryant, Ross W. Mair, Randy L. Buckner, Rebecca Birnbaum, Christian G. Kohler, Cheryl M. Corcoran, Raquel E. Gur, Steven E. Hyman Sep 2026

Schizophrenia Spectrum Biomarkers Consortium: Establishment Of A Biorepository For The Discovery Of Quantitative Fluid Biomarkers, Mohini Ranganathan, Susanne Jakob, Felecia Cerrato, Lia Urban Spillane, Tarlan S. Daryoush, Sophie Shuster, Katherine Dokholyan, Shaynna Herrera, Brian Koo, Clyde Markowitz, Pojen Deng, Sage Rush, Monica E. Calkins, Scott Troyan, Kosha Ruparel, Ruben C. Gur, Holly Reynolds, Claire Wegel, Matthew B. Johnson, Lauren Hom, Sam Bryant, Ross W. Mair, Randy L. Buckner, Rebecca Birnbaum, Christian G. Kohler, Cheryl M. Corcoran, Raquel E. Gur, Steven E. Hyman

Student Publications [Scholarly]

Background and Hypothesis: Schizophrenia spectrum disorders (SSDs) produce severe symptoms, disability, and premature mortality, but only partially effective symptomatic treatments exist. Treatment development is impeded by lack of insight into disease mechanisms or objective biomarkers for clinical trials. Advances in genetics and neurobiology have converged on strong pathogenic hypotheses for SSDs centered on synapse dysfunction and excessive pruning, pathogenic processes that may produce measurable proteomic evidence in cerebrospinal fluid (CSF). Leveraging design precedents from successful fluid biomarkers discovery for Alzheimer’s disease, we undertook a pilot study to test the feasibility of repeated CSF and blood samples collection from individuals with …


Beyond Regulatory Compliance: Reorienting Indonesia's Post-Mining Governance Through Ecological Justice, Suryaningsi Suryaningsi, Rosmini Rosmini, Andi Luthfi, Muhammad Sayyidus Cakrawala Sep 2026

Beyond Regulatory Compliance: Reorienting Indonesia's Post-Mining Governance Through Ecological Justice, Suryaningsi Suryaningsi, Rosmini Rosmini, Andi Luthfi, Muhammad Sayyidus Cakrawala

Hasanuddin Law Review

Post-mining governance in coal-producing regions is often unable to translate regulatory compliance into actual ecological recovery, as evidenced by East Kalimantan's environmental challenges. Therefore, this study aimed to examine implementation gaps in Indonesia's legal framework for reclamation and propose legal reforms grounded in ecological justice. A socio-legal method was used to integrate normative analysis, semi-structured interviews with 12 multi-level stakeholders, and comparative assessments of Australia, South Africa, and India. The results identified four critical gaps, namely discrepancies between administrative compliance and ecological outcomes, inadequate financial assurance, uncertain land transfer, and fragmented institutional oversight. This study showed that regulatory compliance without …


(Wp 2026-04) The Concept Of Position And Its Ontological Meaning In The History Of Economics, John B. Davis Sep 2026

(Wp 2026-04) The Concept Of Position And Its Ontological Meaning In The History Of Economics, John B. Davis

Economics Working Papers

This paper examines the concept of relative position in the history of economics understood as ‘being in a position’ in a structure of positions. This is first discussed in macro-distributional terms in connection with Ricardo and Marx and in micro-behavioral terms in connection with Du Bois and Veblen. The paper then discusses two recent approaches in economics that employ the concept of relative position in a combined macro-micro analysis: the capability approach and stratification economics. For explicitly ontological analysis of the concept, the paper compares three different interpretative strategies from outside economics: Cambridge social positioning theory, embodied and distributed cognition …


Characterization Of Mettl3/14-Mediated M6a Modification In Human Transcriptome Using Nanopore Direct Rna Sequencing, Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Sep 2026

Characterization Of Mettl3/14-Mediated M6a Modification In Human Transcriptome Using Nanopore Direct Rna Sequencing, Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim

Department of Biochemistry and Molecular Biology Faculty Papers

Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism. N6-methyladenosine (m6A), one of the most abundant internal RNA modifications, is deposited by the core methyltransferase complex, METTL3 and METTL14. Oxford Nanopore Technologies (ONT) platform permits direct, single RNA molecule sequencing while preserving native modifications. However, without rigorous benchmarking, the accuracy and reproducibility of modification detection remain uncertain. Here, we leveraged ONT to comprehensively profile bona fide m6A modifications in cellular RNAs at single-nucleotide resolution by integrating two direct RNA sequencing chemistries (RNA002 and RNA004) with the m6Anet and Dorado modification-detection models. We independently depleted METTL3 and METTL14 in human cells …


Inosine-Triphosphate-Pyrophosphatase Activity As A Potential Predictor Of Methotrexate Remission In Juvenile Idiopathic Arthritis., Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore Sep 2026

Inosine-Triphosphate-Pyrophosphatase Activity As A Potential Predictor Of Methotrexate Remission In Juvenile Idiopathic Arthritis., Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Methotrexate (MTX) is the first-line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro.

METHODS: ITPA enzymatic activity was measured by high-performance liquid chromatography with ultraviolet detection in erythrocyte lysates from patients with JIA (enrolled in Trieste, Italy; Florence, Italy; and Kansas City, Missouri) receiving weekly MTX (10-15 mg/m2) for at least 12 months. Remission was evaluated by Wallace et al criteria. ITPA rs1127354, which …


Association Between Estimated Time With Low Glomerular Filtration Rate And Access To Transplant Among Youth With Advanced Chronic Kidney Disease., Elaine Ku, Timothy Copeland, Charles E. Mcculloch, Jonathan D. Savant, Bradley A. Warady, Susan L. Furth, Sarah Kizilbash, Daniel I. Feig, Roshan P. George, Joseph T. Flynn, Judith Jerry-Fluker, Matthew B. Matheson, Sandra Amaral, Ckid Investigators Sep 2026

Association Between Estimated Time With Low Glomerular Filtration Rate And Access To Transplant Among Youth With Advanced Chronic Kidney Disease., Elaine Ku, Timothy Copeland, Charles E. Mcculloch, Jonathan D. Savant, Bradley A. Warady, Susan L. Furth, Sarah Kizilbash, Daniel I. Feig, Roshan P. George, Joseph T. Flynn, Judith Jerry-Fluker, Matthew B. Matheson, Sandra Amaral, Ckid Investigators

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Slower chronic kidney disease (CKD) progression allows more time for transplant preparation. Whether differences in CKD progression by race/ethnicity associate with preemptive or living donor transplantation in youth has not been well studied.

METHODS: We examined the association between time spent with low eGFR (between 10-30 mL/min/1.73 m2) and odds of preemptive or living donor transplantation among youth with CKD. eGFR was estimated using the bedside Schwartz (if < 18 years) and CKD-EPI 2021 equations (if ≥ 18 years) and the CKiD U25 equation in sensitivity analysis. Time spent with low eGFR was compared by race/ethnicity.

RESULTS: Among 333 youth with CKD (median age 11 years [IQR 7,14]), median time spent with low eGFR was 28.8 months. 77% were preemptively waitlisted, and 45% received preemptive …


The Rise And Fall Of Lateral Electrical Surface Stimulation (Less) Through The Lens Of Srs Archives., Ali Rezazadeh Shirazi, Jay I. Kumar, Katie Dold, George H. Thompson, Andrew G. King, Richard M. Schwend, John P. Lubicky, Jay Shapiro, Behrooz A. Akbarnia, History Committee Of The Scoliosis Research Society Sep 2026

The Rise And Fall Of Lateral Electrical Surface Stimulation (Less) Through The Lens Of Srs Archives., Ali Rezazadeh Shirazi, Jay I. Kumar, Katie Dold, George H. Thompson, Andrew G. King, Richard M. Schwend, John P. Lubicky, Jay Shapiro, Behrooz A. Akbarnia, History Committee Of The Scoliosis Research Society

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Lateral electrical surface stimulation (LESS), commercially known as the ScoliTron™, emerged in the late 1970s as a noninvasive alternative to bracing for adolescent idiopathic scoliosis. Early clinical reports generated considerable enthusiasm and adoption, but the technique was ultimately abandoned. This study examined the rise and fall of LESS through a combined analysis of the Scoliosis Research Society (SRS) archives and published literature, with the goal of understanding factors that influence the adoption, evaluation, and abandonment of innovation in scoliosis care.

METHODS: A structured historical review was conducted using archival materials from the Scoliosis Research Society (SRS), including meeting abstracts, …


The Damage Done: How The Disease Model Of Addiction Harms Marginalized People In Canada, Sara Gordon Sep 2026

The Damage Done: How The Disease Model Of Addiction Harms Marginalized People In Canada, Sara Gordon

UBC Law Review

No abstract provided.


Playing Pretend: Why Indigenous Identity Fraud Demands A Crime, Olivia Meier Sep 2026

Playing Pretend: Why Indigenous Identity Fraud Demands A Crime, Olivia Meier

UBC Law Review

No abstract provided.