Digital Commons Network^™

The Effects Of Adipose Tissue Trauma On Vascular Function After Collateral Arteriogenesis, Nathan Tran

Biomedical Engineering

Peripheral artery disease (PAD) affects an estimated 200 million people worldwide and is characterized by arterial narrowing that reduces perfusion to the limbs. Collateral arterioles can naturally restore blood flow through a remodeling process called arteriogenesis, making it a promising therapeutic target. However, the femoral artery ligation (FAL) model used to study arteriogenesis requires surgical access deep to the inguinal fat pad, and approaches for handling the fat pad vary widely across surgeons and protocols. Since adipose tissue harbors a large population of macrophages, the immune cells that govern arteriogenesis, fat pad manipulation may introduce confounding inflammatory stimuli that disrupt …

Bacterial Adaptation To Radiofrequency Electromagnetic Fields Based On Experiences From Ionizing Radiation, Ilham Said-Salman, Seyed Mohammad Javad Mortazavi, Sami El Khatib, Seyed Alireza Mortazavi, Lembit Sihver

Informatics and Engineering Systems Faculty Publications

Bacteria, part of the three domains of life (Eukarya, Archaea, and Bacteria), are constantly exposed to man-made electromagnetic fields, which often exceed the intensity of natural electromagnetic sources. In response to this exposure, bacteria have developed various defensive and resistant traits. This article presents an overview of both historical and recent research on how bacteria adapt to common sources of Radiofrequency Electromagnetic Fields (RF-EMF). The widespread use of mobile phones and Wi-Fi, both utilizing Radiofrequency (RF) radiation, raises potential public health concerns, which have been addressed by international organizations like the World Health Organization (WHO). Understanding how bacteria adapt to …

Satellite-Based Forest Structure Metrics As A Predictive Tool For Biodiversity In Hyperdiverse Tropical Forests: A Test Of The Habitat Heterogeneity Hypothesis In The Tropics, David Luther, Marconi Campos-Cerqueira, Aline Medeiros, Aidan Mccarthy, Emilia Roberts, Xiaoxuan Li, Paulo Bobrowiec, Jared Wolfe, Gabriel Augusto Leite, Tomaz Nascimento De Melo, José W. Ribeiro, Thiago Bicudo, Konrad Wessels

Michigan Tech Publications

Tropical forests hold the most species yet face the greatest threats and knowledge gaps. To improve tropical biodiversity knowledge we combined satellite-based LiDAR with in situ bird, mammal, and acoustic soundscape data, via camera and audio recorders, at the Biological Dynamics of Forest Fragments Project in the Amazon rainforest and tested the habitat heterogeneity-diversity hypothesis as a predictor of alpha diversity in tropical forests. GEDI spaceborne LiDAR was used to assess the predictive power of vertical forest structure on acoustic diversity and species diversity in lowland tropical forests. In 4 months, we detected 201 bird and 35 mammal species representing …

The Wake Of Addiction: Pharmacological Strategies For Sleep Disturbances In Stimulant Use Disorders, A Systematic Review, Isabella G Bourtin, Douglas J Calvillo, Jessica C Badawi, Joy M Schmitz, Scott D Lane, Jin Ho Yoon, Heather E Webber

Faculty, Staff and Student Publications

Background: A systematic review was conducted following PRISMA guidelines to identify human studies investigating pharmacological interventions and reported sleep outcomes among individuals with CUD or MUD.

Methods: PubMed and APA PsycInfo were searched from inception to January 2025 and risk of bias was assessed. Articles were included if they included human participants with either cocaine or methamphetamine dependence, administered a pharmacological treatment, and reported night-time sleep as an outcome using at least one rigorous measurement tool. Articles were excluded if they included animals, did not include pharmacological intervention (e.g., supplements or behavioral treatments), or only assessed baseline sleep or if …

Invasion Patterns And Niche Dynamics Of The Pollinivorous Florida Calligrapher, Toxomerus Floralis (Diptera: Syrphidae) In The Afrotropical Region, Burgert Muller, John Midgley, Georg Goergen, Ali Al Jahdhami, Michelson Azo'o Ela, Terence Bellingan, Simon Cavaillès, Robert Copeland, Marc De Meyer, Martin Hauser, Allen Holmes, Ximo Mengual, Gabriel Nève, Menno Reemer, Jeff Skevington, Gunilla Ståhls, Eugène Sinzinkayo, John Smit, Axel Ssymank, Genevieve Theron, Kurt Jordaens

All Peer-Reviewed Publications

The rapid spread of Toxomerus floralis (Fabricius, 1798) (Diptera: Syrphidae) within the Afrotropical region is described. We characterise and compare the climatic niches of T. floralis in its native (Southern North America, Central America and South America) and invaded (Afrotropical Region) range to assess the potential for further expansion across Africa and beyond, and included future global climate models and socioeconomic pathways as projections. Occurrence data for native and invaded ranges were obtained from field sampling by authors, major collections of Afrotropical Syrphidae, collections records and occurrence data from the Global Biodiversity Information Facility (GBIF), including iNaturalist data. Single and …

Climate-Driven Stochastic Modelling Of Crimean-Congo Haemorrhagic Fever Transmission In Uganda, P. G. Kpatchana, J. Aduda, K. M. Agboka

All Peer-Reviewed Publications

Crimean-Congo haemorrhagic fever (CCHF) is a climate-sensitive tick-borne zoonosis that remains a significant public health concern in Uganda, where temperature and vapour pressure deficit influence tick ecology and consequently disease transmission. This study aimed to develop and analyse a climate-driven stochastic model for CCHF transmission among ticks, livestock, and humans under environmental variability in Uganda. A compartmental transmission model was formulated and extended into a stochastic differential equation framework by incorporating multiplicative environmental noise. Climate-dependent tick recruitment, development, and mortality were parameterized using district-level temperature and vapour pressure deficit data to capture spatial heterogeneity in transmission risk. Theoretical analyses based …

From Institutions To Families: Assessing The Progress Of Egypt’S National Strategy For Alternative Child Care Reform, Yasmine M. El Hagry

Theses and Dissertations

This study serves as a critical mid-term review of the Egyptian National Strategy for Alternative Care for Children and Youth without Parental Care (NACS) (2021-2030). The 10-year strategy overall goal is to shift from institutional care, such as orphanages, to family-based care, such as kafala, the Islamic alternative to legal adoption, for children deprived of parental care. While the global literature strongly advocates deinstitutionalization, empirical research on the operational risks and unintended harms that can arise during such complex transformations remains scarce.

Adapting the International Civil Service Effectiveness (InCiSE) Framework, this research uses a qualitative approach to diagnose the …

The Other Within: Stigmatization And Marginalization Of Hui Muslims In The Novel Musilin De Zangli (Muslim Funeral), Flávio Fraga Da Silva

Perspectives in the Arts and Humanities Asia

This article offers a case study of the protagonist of the novel Musilin de Zangli by Huo Da, as a representation of the stigmatization and marginalization of the Hui Muslim community in Beijing in the early 1960s. Drawing on this portrayal, the novel’s subliminal and allegorical dimensions, and an examination of the mechanisms of “domestic othering” operative in Maoist China, the study discusses how the text advances a veiled critique of the abuses and excesses experienced by this community in the period leading up to, and including, the Cultural Revolution. By situating the text within its broader sociocultural and historical …

Exploring The Role Of Vitamin D In Familial Mediterranean Fever: Pathogenesis, Triggers, And Immune Modulation, Hagop Sassounian, Saad Aad, Hilda E. Ghadieh, Lara Khouzami, Elsa Nicolas, Sami Azar, Frederic Harb

All Works

Familial Mediterranean Fever (FMF) is among the most frequent autoinflammatory diseases in populations originating from the area of Middle Eastern and Mediterranean countries. It is caused by mutations in the MEFV gene, which causes dysregulated pyrin expression and thus an immunologic anomaly. FMF is diagnosed by recurrent episodes of fever and serosal inflammation, predominantly peritonitis and pleuritis, as well as other systemic symptoms. Recent research is dedicated to searching for factors beyond genetic code contributing to how FMF evolves, the severity of its symptoms and response to conventional therapy—colchicine. These factors include epigenetic modifications of the MEFV gene and other …

The Development Of The Daughter-Guarding Scale: An Exploratory And Confirmatory Factor Analytic Study, Ray Garza, Farid Pazhoohi

School of Psychology

Fathers represent one of the earliest opposite-sex relationships for daughters, and it has been suggested that fathers may shape their daughters' developmental trajectory. Fathers are often stricter with their daughters compared to sons in monitoring and correcting behaviors, most notably in the avenue of social and sexual monitoring. Nonetheless, there are no valid measurement tools for capturing the different factors associated with daughter-guarding by fathers. The current study proposed an instrument for addressing daughter-guarding as reported by fathers. In Study 1, an exploratory factor analysis showed that 3-underlying factors were present in daughter-guarding, such as social monitoring of friends, guarding …

The Effects Of Adverse Childhood Experiences On Female College Students' Social Emotional Development: Is Flourishing Possible?, Kaylee Kirkwood

University Honors Theses

Adverse childhood experiences are events of trauma and abuse that occur prior to age eighteen. High rates of sexual violence against girls and female undergraduate students inspired this study to explore how trauma may impact development and overall college experience. This thesis employed a small exploratory pilot study to investigate childhood trauma and social-emotional development among a small sample of female college students (ages 18-25; n = 41). Participants recruited through the Prolific Database completed an online Qualtrics survey consisting of screeners, demographic questions, measures of trauma history and emotional functioning, and optional open-ended experience-based questions. Measures were guided by …

Viruses Causing Panleukopenia In Domestic Cats: A Review Of Feline And Canine Parvoviruses, Simon Colby

University Honors Theses

Parvoviruses remain among the most important viral pathogens in domestic cats today. Despite this, there is much confusion around which parvoviruses can infect cats, and what extent of disease they can cause. One of the two parvoviruses infecting cats, canine parvovirus type-2 (CPV-2), likely evolved from the other parvovirus infecting cats, feline parvovirus (FPV). These viruses differ at only a few places in their genomes, and share the method of cell entry via the transferrin receptor. The disease caused by FPV has been well characterized in cats, but disease caused by CPV-2 is more obscure. Additionally, current testing methods for …

Interrupted By Design: The Impact Of Push Notifications On Stress And Task Performance, Mia Hohmann

University Honors Theses

As digital communication becomes unavoidable at work, notifications have become one of the most common and overlooked sources of interruption. Drawing from current technostress literature, this study investigates how notifications impact acute and perceived stress as well as task speed and accuracy. In an experimental setting, employed university students (N = 35) completed a data-entry task while receiving either no notifications, task-relevant notifications or task-irrelevant notifications to examine how different types of digital interruptions influenced stress and performance. Stress was measured through a pre- and post-task survey and performance was assessed through both speed and accuracy. Although results showed significant …

The Dolor: How A Generation Of Women Quietly Lost Their Children, Alexis Mclean

University Honors Theses

This thesis is an exploration of the phenomenon of increased adoption rates between the years of 1945 and 1973 and attempts to establish a cohesive explanation for and image of the experience of these birth mothers. My research found that adoptions during this time period are generally characterized by the utilization of maternity homes, coercion, and secrecy. The typical birth mother during this time was white and middle class, emblematic of the motivations of their adoptions: to maintain an idealist image of their motherhood and maintain socioeconomic status. Despite this position framed by privilege, these women too often report having …

Applications Of Prior And Novel Computational Tools In Mental Health Treatment, And Their Potential To Uncover The Explanatory Gap, Ambika Vyas

University Honors Theses

The explanatory gap is a widely discussed concept in scientific and philosophical literature. In neuroscience, the solution to the explanatory gap is highly sought out, but the general consensus is that it is unsolvable. Numerous articles discuss the explanatory gap alongside computational tools and how these tools could aid neuroscientists in uncovering the mental health explanatory gap. However, significant developments in machine learning have been made since 2020, coinciding with the rise in Large Language Models (LLMs). This thesis is a literature review on computational methods, tools, and devices developed and utilized by researchers to improve how mental health disorders …

Exploring The Durability Of Marine Picocyanobacterial Microcolonies, Erik Swanson

University Honors Theses

Picocyanobacteria of the genus Synechococcus are widespread aquatic photoautotrophs that play essential roles in primary production and carbon cycling. Some Synechococcus strains form multicellular microcolonies, but the mechanisms of cell-to-cell attachments and structural durability of these microcolonies remain poorly understood. This research investigated the physical durability of microcolonies in two marine Synechococcus strains (CC9605 and CC9311) using physical disruption treatments. Cultures were subjected to vortexing and sonication treatments, and populations of single cells and microcolonies were quantified using flow cytometry based on differences in measures of size. Results indicated that strain CC9605 showed no significant treatment effect, whereas CC9311 displayed …

Developing A High-Resolution Off-Axis Common-Mode Digital Holographic Microscope, Lucy Cook

University Honors Theses

Off-axis digital holographic microscopy (DHM) is a powerful tool for 3D, non-invasive live-cell tracking without moving parts. However, traditional setups face an inherent dilemma: split-path interferometers offer high spatial resolution but poor temporal stability, while more stable common-mode configurations are historically limited to lower numerical aperture (NA) regimes. This thesis bridges that gap by scaling a common-mode DHM architecture into a high-resolution benchtop instrument featuring NA = 0.65 objectives, paired with a high-power 520 nm laser source to combat transmission losses and sustain imaging frame rates across an expanded optical footprint. We map the multi-variable design space required to satisfy …

Grief, Silence, And Surveillance In Academic Settings, Rakhi Grey

University Honors Theses

This study examines how grief is silenced, monitored, and regulated within higher education settings. Drawing on semi-structured interviews with undergraduate students who experienced the death of someone significant, this study explores how institutional expectations surrounding productivity, professionalism, emotional control, and academic functioning shape grief disclosure, emotional expression, and help-seeking behaviors. Using a critical theoretical framework informed by concepts of disenfranchised grief, legitimacy hierarchies, and surveillance, findings suggest that grief within higher education is not simply individually experienced, but socially and institutionally regulated. Participants described academic environments that often left little space for ongoing grief, requiring students to compartmentalize emotional distress, …

Psychological Architecture: Evaluating The "Greenhouse Model" As A Structural Standard For Lgbtq+ Well-Being, Ava Lee

University Honors Theses

Traditional LGBTQ+ mental health frameworks often conceptualize psychological safety as a matter of individual endurance. This paper critiques this focus on adaptive resilience, which systematically shifts responsibility from institutions to individuals. To counter this, the study introduces "Psychological Architecture," a framework viewing social environments as constructed infrastructures that can either support or undermine queer well-being. The model contrasts performative "Glasshouses," which prioritize visibility over safety, with engineered "Greenhouses" that nurture sustainable safety through three sequential pillars: Authentic Representation (walls), Emotional Validation (insulation), and Vocal Activism (ventilation).

Grounded in the findings of a 2024 qualitative pilot study of a queer roller …

Fundamentalist Disorientations For Queer Subjects: Narrative And Theory, Betty Canoso

University Honors Theses

This thesis examines disorientation experienced by queer people who were raised in high-cost fundamentalist Christianity–people like me. Disorientation is a philosophical concept useful for examining specific intersections of human experience, like queerness and fundamentalism. Philosophers such as Sara Ahmed (2006) and Ami Harbin (2016) have been exploring the intersection of queerness and disorientation. Psychologists, sociologists and researchers from other disciplines are analyzing the interrelatedness of queerness and religion, and disaffiliation and deconversion from high-cost or high-control religions is another ongoing area of interest. Yet, despite widespread interest in these concepts, few have looked at instances of disorientation as they pertain …

"I Still Care About Her": Ambiguous Loss And Social Death In Substance-Affected Relationships, Margaret M. King

University Honors Theses

Substance use creates a ripple effect, affecting the individual as well as their family members. The struggles associated with problematic substance use result in feelings of ambiguous loss towards the substance using individual, a type of loss in which a person is still living but either psychologically or physically unavailable. This research explores the experiences of ambiguous loss in college students with loved ones struggling with substance use, examining how they are thrust into caregiving roles, experience support, and find meaning within their loss. Seven semi-structured interviews were held with adult college students who identified as having a loved-one struggling …

Shallow-Marine Crinoid Genera May Have Been More Resilient Across Permian Extinction Events In Terms Of Richness Than Deep-Marine Crinoid Genera, Amelia C. Kolstad

University Honors Theses

Throughout the Phanerozoic, one of the most successful phyla of marine invertebrates has been Echinodermata. Echinodermata was particularly successful throughout the Paleozoic, with class Crinoidea making up a majority of occurrences. The proportion of echinoderm occurrences that are crinoids declined massively at the end of the Permian and continued to decrease into modern day, never fully recovering. One of the factors thought to have been so important for crinoid success in the Paleozoic and their decreasing success throughout geologic time has been their propensity for success in shallow-marine environments, though crinoids also exist within deep-marine environments. This study seeks to …

Moving Beyond Traditional Cost Containment For Glp-1 Coverage Within Oregon's Proposed Universal Health Plan, Manoj Rajesh

University Honors Theses

In 2022, Oregon voters passed Measure 111, constitutionally mandating access to affordable health care. As the Universal Health Plan Governance Board (UHPGB) designs the state's proposed single-payer system, it faces an unprecedented financial vulnerability: the clinical demand for GLP-1 receptor agonists. These high-cost, indefinite-use medications for obesity and metabolic syndrome threaten to overwhelm fixed public budgets. Historically, both the Oregon Health Plan's Medicaid framework and commercial private insurers have relied on static cost-containment models—categorical exclusions, step therapy, and aggressive utilization management—that achieve short-term fiscal solvency at the expense of comprehensive preventative care. This thesis argues that to fulfill the mandate …

Routine Transfusion Of Rh(D)-Positive Rbcs To Rh(D)-Negative Patients Designated As Do Not Resuscitate Conserves Rh(D)-Negative Red Blood Cell Inventory, Julie Katz Karp, Jovanna Everetts, Juliana Guarente, Angelica Vivero, Tiffany Bohr, Mary Harach

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background: A minority of blood donors are Rh(D)-negative, and Rh(D)-negative red blood cell (RBC) products are often overutilized. As such, Rh(D)-negative RBCs may be difficult to maintain in blood bank inventory.

Study design and methods: We changed our blood bank laboratory policy to approve non-alloimmunized Rh(D)-negative patients to receive Rh(D)-positive RBCs for routine transfusion under defined criteria. Those criteria included Rh(D)-negative males (all ages) and females (aged >50 years) who were designated as do not resuscitate (DNR), either with or without intubation, in the electronic medical record.

Results: From August 15, 2024 through August 15, 2025, a total of 204 …

A Decade Of Leadership And Impact: Celebrating 10 Years Of The Ors Spine Section, Makarand V. Risbud

College of Life Sciences Faculty Papers

No abstract provided.

Socio-Ecological Models As A Framework For 21st-Century Genetic Counseling, Shana L. Merrill, Rebecca Mueller

College of Life Sciences Faculty Papers

Socio-ecological models and the related concepts of micro-, meso-, and macro-level practice are commonly used in the fields of social work and public health yet have not been thoroughly conceptualized for application to genetic counseling practice, research, and training. The field of genetic counseling is currently undergoing significant expansion with more genetic counseling training programs, greater variation in genetic counselor job roles, and genetic counselors practicing in more globally dispersed regions. It is therefore a critical time to conceptualize and tailor relevant theoretical frameworks to unify and guide the evolving field of genetic counseling. In this paper, we posit that …

Campus Community Vibes: How Queer Asian American Students Navigate Their Higher Education Experiences, Nathan Nguyễn

Dissertations

Misconceptions and stereotypes about Asian American college students include the belief that they are innately academically successful and that if Asian American students struggle, their challenges do not compare to their Black/African American, Hispanic/Latine, or Native American/Indigenous counterparts (Museus & Buenavista, 2016). Contemporaneous to this, lesbian, gay, bisexual, transgender, and queer (LGBTQ) college students experience interrogation, exploration, and various levels of support regarding their sexuality and/or gender identity. At this intersection, queer Asian American students must navigate campus settings that can enhance or diminish their agency for different facets of their identities (Crenshaw, 1991; Iftikar & Museus, 2018; Ray, 2019). …

Long-Covid And Cognition, Mychael Bruce

Dissertations

COVID-19 is an evolving virus that can harm the body’s respiratory and cardiovascular systems. Directly related to COVID-19 are individuals who do not recover from their initial infection, making them long haulers. Long-COVID is transitioning from a range of isolated phenomena to higher prevalence rates in patients who contracted COVID-19. Many individuals report issues with cognitive function, referred to as ‘brain fog’, that affect memory, attention, and even language skills. This literature review addresses the available research on Long-COVID and how persistent infection correlates with cognitive difficulties. It aims to explain the neurobiology of Long-COVID and how Long-COVID interacts within …

Evaluation Of Neuroplastic Changes In Psychological Intervention And Contemporary Treatments Of Depression, Taylor Severance

Dissertations

Major depressive disorder is one of the most prevalent mental health disorders worldwide. There is a vast range of treatment options for depression, with varying levels of effectiveness. Recent treatments for depression have expanded, increasing alternative treatments, and it is unknown which treatments have the largest impact on depression. This research was designed to examine the treatments of depression, with a focus on psychotherapy and contemporary treatments such as ketamine, psilocybin, and transcranial magnetic stimulation. A literature review was conducted to assess treatment outcomes and neuroplastic changes in these interventions, as well as combinations of the interventions. Data were evaluated …

Exercise Therapy For Mood Disorders In Retiring/Former Athletes, Christian Antos

Dissertations

This dissertation examined the potential integration of exercise therapy and psychotherapy as a treatment approach for mood-related difficulties experienced by former elite athletes during the transition out of competitive sport. Retirement from athletics is often associated with significant biopsychosocial challenges, including disruptions in identity, healthy routines, social support, and emotional well-being. Existing literature suggests that exercise may serve as an effective adjunctive intervention for improving mood and overall psychological functioning, though limited research has explored its application among retiring athletes within psychotherapeutic contexts. This literature review synthesized current research related to athletic retirement, neurobiological mechanisms associated with physical activity, and …