Digital Commons Network^™

Wellness, Transhumanism, And The Death Of Health Law, Leah Fowler

UMKC Law Review

No abstract provided.

Collagen Gene Expression Is Linked To Aging And Lifespan Extension In C. Elegans, Archer J. Wang, Blake M. Geppert, Daniel Beck, Yanqing Ji, Yiyong Liu

Electrical & Computer Engineering Faculty Scholarship

Collagens, long regarded as structural molecules, also regulate stress responses and longevity. In this study, we analyzed our RNA sequencing data and publicly available gene expression data to define their role in Caenorhabditis elegans aging. Collagen expression broadly declined with age, with 16 collagen genes consistently downregulated across independent studies, establishing collagen downregulation as a genetic hallmark of aging. In contrast, meta-analysis of 66 datasets (128 comparisons between normal and long-lived animals) showed collagen upregulation in 84% of long-lived conditions, identifying collagen induction as a conserved signature of lifespan extension. Using π-values to integrate fold change and significance of …

Centering Well-Being And Wholeness: Exploring Racial Battle Fatigue Among Black 3-K To Twelfth-Grade Teachers, Olubunmi Fashusi

Theses and Dissertations

This qualitative case study, with some descriptive statistics, examined Black 3-K through 12th- grade teachers’ experiences with racial battle fatigue (RBF), the psychological and behavioral stress responses they perceived most accurately convey how RBF manifests for them, and the strategies they used to disrupt RBF’s impact. Participants experienced compounded RBF due to advocating for students (i.e., speaking out, supporting, or intervening). Participants’ most perceived psychological stress response to RBF was racism awareness, and most perceived behavioral stress response was spirituality or religion. Participants disrupted the impact of RBF through intrinsic care (i.e., purpose or why, managing emotions, and self-care) and …

June 2026 Library News, University Libraries

Library News

No abstract provided.

Returning With The Elixir: Transformation In Two Young Adult Novels, April Vázquez

Language Arts Journal of Michigan

The narrative structure of the Hero’s Journey, first elaborated by Joseph Campbell in 1949, is employed in Pashmina by Nidhi Chanani and Patron Saints of Nothing by Randy Ribay. In these two works for young people, the protagonists travel to their parents’ native countries, encountering systems of oppression that fundamentally transform their perspectives and alter the trajectories of their lives. Each character follows the same narrative pattern: before the Hero’s Journey, they have led mostly unremarkable lives, have an encounter with the supernatural or the divine, confront systemic oppression in their parents’ native countries on a scale beyond what they …

Updates To The Caniform Fauna (Carnivora, Caniformia) Of The John Day Formation, Oregon, Usa, John D. Orcutt, Kevin C. Talbott, Michael J. Monroe, Nicholas A. Famoso

Biology Faculty Scholarship

The John Day Formation of central Oregon preserves a diversity of Oligo-Miocene caniform carnivorans, many of which were first described from the formation. However, many historically important specimens lack detailed locality or stratigraphic information, complicating any analysis of faunal change through time. Here, we describe 16 new specimens of caniforms from the John Day Formation, most with precise stratigraphic information. We report multiple specimens of the amphicyonids Daphoenus Leidy, 1853, Paradaphoenus cuspigerus (Cope, 1878), and Temnocyon altigenis (Cope, 1878), all previously known from the formation. We also report the first definitive occurrence of the hesperocyonine canid Osbornodon Wang, 1994 from …

Effect Of Leaf Harvesting Frequency On Cassava Leaf Production And Tuber Yield Of Binulak, Lakan 1 (Upl Cv-2), And Sultan 6 (Nsic 2003 Cv-25), Fides Marciana Z. Tambalo, Rosa Buena A. Capuno, Hiyasmin Rose L. Benzon, Jayson F. Garcia, Lizette Sahar N. Arcillas, Rona Joy C. Tud

The Philippine Agricultural Scientist

Cassava (Manihot esculenta Crantz) is a vital staple crop in many developing countries, valued for its adaptability and dual-purpose use of roots and leaves. This study investigated the effects of leaf harvesting frequency on the leaf and tuber yields of 3 locally grown cassava varieties: Binulak, Lakan 1, and Sultan 6. The experiment followed a split plot in a Randomized Complete Block Design with 4 treatments varying in leaf harvesting frequency and initiation. Cassava leaves were harvested at 4, 6, 8, or 10 mo after planting (MAP), and tubers were harvested at 10 MAP. Results indicated that leaf yield …

In Vitro Assessment Of The Reproductive Biology Of Sweet Potato Weevil, Cylas Formicarius (Fabricius) (Coleoptera: Brentidae) Among Commonly Grown Sweet Potato Cultivars, Jerah Mystica Novenario, Flor A. Ceballo-Alcantara

The Philippine Agricultural Scientist

The sweet potato weevil, Cylas formicarius (Fabricius), is a devastating pest of sweet potato, Ipomoea batatas (L.) Lam., with a specific point of damage at the tuber where eggs are oviposited, and voracious larvae feed. Farmers in Tarlac province in the Philippines claim that a specific cultivar is highly infested by the pest, suggesting that other cultivars may not be susceptible to the pest damage. This study aimed to determine the reproductive biology of the weevil across 3 sweet potato cultivars (Inubi, Super Bureau, and Bureau) frequently grown in Central Luzon. Since the weevils are nocturnal, behavioral observations were conducted …

Filtered Genome Of Commercial Philippine Varieties Of Sugarcane (Saccharum Officinarum L.) For The Characterization And Identification Of Ssrs Associated With Resistance To Philippine Downy Mildew (Peronosclerospora Philippinensis), Antonio G. Lalusin, Jhun Lawrence S. Rasco

The Philippine Agricultural Scientist

Sugarcane is a major global source of sugar, with total production reaching 1.89 billion t. Although the Philippines produces about 1.85 million t of sugarcane annually, yields are limited by downy mildew and smut. Developing varieties resistant to these pathogens is the most economical and practical approach to mitigating losses from these biotic stresses. In this study, SSRs related to disease resistance were developed through Next-Generation Sequencing (NGS) of the filtered genomes of sugarcane varieties with known phenotypic responses to downy mildew. Two assemblies based on minimum contig lengths (450 and 900 bp) were performed using SoapDeNovo2. The 900-bp assembly …

Marker-Assisted Identification Of Hybrids In Polyembryonic ‘Carabao’ Mango (Mangifera Indica L.) Breeding In The Philippines, John Edward L. Felipe, Kyla Andrea G. Mendoza, Benjamin Christian J. Esguerra, Carolyn E. Alcasid, Gino R. Hernandez, Eureka Teresa M. Ocampo

The Philippine Agricultural Scientist

Varietal improvement of the Philippine ‘Carabao’ mango (Mangifera indica L.) through conventional breeding is constrained by polyembryony, which makes it difficult to distinguish zygotic hybrids from nucellar seedlings at early developmental stages. This study evaluated the utility of simple sequence repeat (SSR) markers for early and accurate identification of hybrids in polyembryonic ‘Carabao’ mango crosses. Genomic DNA was isolated from 24 parental accessions and 61 putative hybrid seedlings using a modified CTAB protocol that yielded DNA suitable for PCR-based marker analysis. Eighty-one SSR markers were screened across 29 parental combinations, of which 64 markers (79.0%) were polymorphic in at …

Spatial Variation In Soil Quality Across Selected Fruit Tree Plantations In Bacnotan, La Union, Philippines, Jay Mark G. Cortado, Roberto G. Visco, Jenielyn T. Padrones, Pastor L. Malabrigo Jr

The Philippine Agricultural Scientist

Sustaining soil quality on any plantation is critical to increasing productivity and responsible land use. However, spatial variation in soil quality across fruit tree plantations under existing field and management conditions remains insufficiently documented. This study aimed to assess the soil quality of monocropped plantations of banana, calamansi, coffee, and rambutan in northern Luzon, Philippines, evaluate the extent of degradation or improvement relative to a reference forest using the Soil Quality Index (SQI) approach, and identify the soil indicators that significantly influence soil quality in these plantations. The objectives were to determine which fruit tree plantations could enhance soil quality …

Postharvest Response Of Jute Mallow (Corchorus Olitorius L.) Tops To Different Storage Temperatures, Wella L. Absulio-Morales, James L. Tababa, Daphne Cassandra H. Gonzales, Genesis M. Banawa, Angelo C. Castro, Arlan James D. Rodeo

The Philippine Agricultural Scientist

Jute mallow (Corchorus olitorius L.), locally known as saluyot, is a nutrient-rich leafy vegetable, but its potential remains underutilized due to its high perishability. This study determined the postharvest behavior of jute tops stored at 4 different temperatures (5, 13, 20, and 28 °C). Key quality parameters were measured at specific time intervals. The marketable shelf life of jute tops was 7 d at 5 and 13 °C, but only 2 and 3 d at 28 and 20 °C, respectively. This shorter shelf life was mainly due to wilting caused by high weight loss, especially at higher temperatures. …

Evaluation Of Alternative Solvents For Electrospinning Occluded Scaffolds To Model Intracranial Atherosclerotic Disease In Blood Vessel Mimics, Olivia D. Rankin

Master's Theses

Intracranial atherosclerotic disease (ICAD) is characterized by a buildup of fatty plaque within the walls of arteries supplying the brain, resulting in vessel narrowing, restricted blood flow, and increased risk of ischemic stroke. While various treatments exist for ICAD, most are accompanied by high recurrent stroke rates and other adverse events, highlighting the need for further investigation and models for pre-clinical testing. Tissue engineered Blood Vessel Mimics (BVMs), consisting of a polymer scaffold sodded with human vascular cells, serve as physiologically relevant in vitro models for vascular device testing. This thesis focused on the application of alternative solvents to a …

Off-Label Neuroimaging, Jane C. Moriarty

Law Faculty Publications

The growth of neuroimaging evidence in the courtroom is consistent with the increased reliance on technical and machine-based specialties at trial. Litigants routinely seek to introduce neuroimaging evidence in both civil and criminal trials to supplement traditional medical, psychiatric, and psychological opinion testimony. A substantial portion of neuroimaging evidence is still in the developmental stage—what I term “off-label neuroimaging.” Unsurprisingly, evaluating the reliability of developing neuroimaging poses challenging questions for gatekeeping courts. Among the complex evidentiary issues neuroimaging presents for courts and litigants, this Article considers one foundational question: How should courts determine whether neuroimaging evidence is sufficiently reliable for …

Response To Kodali Et Al., “Hailey-Hailey Disease: A Review And An Approach To Management”, Christina Tolete, Teresa Duong, Adam Friedman, Leonardo Tjahjono

Department of Medicine Faculty Papers

No abstract provided.

Electrically Evoked Emg Decomposition Using The Perturbative Generalized Series Expansion, William R. Walker

Master's Theses

Electrically evoked electromyography records the muscle's response to nerve stimulation and has been used for clinical assessment of neuromuscular function, as well as treatments such as functional electrical stimulation or stroke rehabilitation. In every muscular contraction, an electrical signal is generated. These signals come from the summation of simultaneously recruited motor units, enabling decomposition techniques to reveal information about motor unit recruitment.  By improving the ability to decompose and analyze these signals, clinical treatments involving neuromuscular electrical stimulation can be optimized and better understood. Much of the research on EMG analysis focuses on voluntary EMG, leaving a gap in the …

Increasing Lead (Pb) Screening Participation Rates In The Pediatric Patient Population At The Philadelphia College Of Osteopathic Medicine Lancaster Avenue Community Healthcare Center, Jacob Varrato

PCOM Biomedical Studies Student Scholarship

Elevated blood lead levels (EBLLs) are an ongoing public health crisis predominantly affecting children under six in low-income communities located in major cities across the United States (Zartarian et al. 2024). Chronic lead exposure due to outdated housing, polluted water, and contaminated soil is especially harmful in early childhood. Frequent hand to mouth contact at this age increases the risk of ingesting particulate matter containing lead (CDC). EBLLs can predispose children to neurocognitive deficits, cardiovascular disease, and epigenetic modifications to gene expression patterns (Collin et al. 2022). While precautionary measures and timely screening protocols greatly reduce the risk of developing …

Effects Of Mitoquinone On Doxorubicin-Induced Cytotoxicity In H9c2 Cardiac Myoblasts And 22rv1 Prostate Cancer Cells, Tia Patrick

PCOM Biomedical Studies Student Scholarship

Introduction:

Although Doxorubicin (DOX) is a widely prescribed chemotherapeutic agent, its clinical use is limited by cardiotoxicity (DIC) caused by oxidative stress, mitochondrial dysfunction, and cardiac apoptosis. Dexrazoxane (DEX) is the only FDA-approved cardioprotective agent to prevent DIC. However, DEX may induce secondary malignancy. Mitochondria-targeted antioxidants (MTAs), such as mitoquinone (MitoQ) and 10-(6′-plastoquinonyl) decyltriphenylphosphonium (SKQ1), selectively accumulate within mitochondria to scavenge reactive oxygen species (ROS) at their primary site of production. Our previous findings demonstrated that MitoQ and SKQ1 prevented the reduction in cell viability caused by DOX treatment in H9c2 myoblasts. However, it remains unclear whether MitoQ can selectively …

Foreword, Allison M. Whelan

Georgia State University Law Review

No abstract provided.

Addressing Homelessness And Hunger Through A Human Rights Approach Focused On Collective Responses, R. Denisse Córdova Montes, Tamar Ezer

Georgia State University Law Review

The United States is experiencing unprecedented levels of homelessness and food insecurity. In 2024, the number of unhoused persons on a single night reached the highest ever recorded, and in 2023, 13.5% of the population lived in food insecure households, including 7.2 million children. Both homelessness and food insecurity disproportionately impact individuals based on race and gender.

In this context, community-led tools, such as community kitchen events and public feedings, have played an important role in providing those experiencing extreme hardship with access to adequate food and safe community spaces.

However, rather than supporting these efforts or addressing the root …

Shared Language For Responsible Ai Integration, Asa B. Stone, Mark C. Stone, Alisha Bevins, Jean Claude Niyomugabo, Irene Magara, Jacob Abaare, Derek M. Heeren, Mubarak Abu Zouriq

PRAIRIE: Pioneering Responsible AI for Research, Innovation, and Education

As AI rapidly reshapes how we work and learn, employers increasingly seek graduates who can think before they prompt, exercising judgment under pressure rather than merely producing output. Yet students are praised for AI use in one course and penalized for it in the next, and faculty are left to lead responsibly on shifting ground, with no shared language to guide them.

This paper introduces the PRAIRIE Framework for AI Integration, a shift from reactive gatekeeping toward proactive stewardship. It emerged from a qualitative sentiment analysis of three communities (students, faculty, and industry partners) whose concerns converged on one need: …

Teaching Learning Newsletter Vol 6 Issue 1, Sastra Deemed To Be University

TLC Newsletter

No abstract provided.

New Age Spirituality In Post-Secular Turkey: Navigating Secular Sensibilities And Class Privilege, Zeynep Ozbarlas

Dissertations, Theses, and Capstone Projects

The conflict between religion and secularism has been one of the major forces shaping Turkey’s socio-political landscape since the late nineteenth century. With the radical secular turn during the founding of the Turkish Republic, secularism remained the dominant force until the rise of political Islam in the 1980s. This dissertation, grounded in ethnographic fieldwork, argues that New Age spirituality, adopted by the secular upper-middle class, has become an alternative venue for the reproduction of secular sensibilities and socio-economic privilege in contemporary Turkey, at a time when the two-decade tenure of the Erdoğan regime has undermined secular hegemony.

Although New Age …

New York State Excelsior Scholarship Program: A Post-Implementation Analysis Of Student Success, Eligibility, And Indebtedness – An Intersectional Study Of Black And White Female Students, Marcus I. Richardson

Dissertations, Theses, and Capstone Projects

The New York State (NYS) Excelsior Scholarship Program, introduced in 2017, was designed as a “first-in-the-nation” tuition-free initiative intended to expand college affordability for undergraduate students attending public institutions in New York State. While the program aims to increase access to higher education, its eligibility requirements, particularly the expectation that students complete 30 credits annually through continuous full-time enrollment, may disadvantage students whose academic pathways diverge from traditional enrollment patterns. This study examined the relationship between structural, financial, and academic factors and students’ ability to retain Excelsior Scholarship eligibility at the City University of New York (CUNY). Using institutional data …

Radiotheranostics For Gynecological Pathologies, Joni Sebastiano

Dissertations, Theses, and Capstone Projects

Molecular imaging, specifically positron emission tomography (PET), is vital for detecting disease and understanding its biological makeup. The exploitation of radiolabeled antibodies for PET imaging has proven to be indispensable to the field of molecular imaging over the last several decades. The development of radioimmunoconjugates for use in immunoPET has not only allowed for the sensitive, specific, and high-resolution detection of disease, but has also enabled a deeper understanding of the disease biology, ultimately guiding more personalized therapeutic strategies. Most typically, this technology is harnessed for the diagnosis and treatment of cancer, however more recently, the field has explored the …

A Comparison Of Manufacturers’ Claims Of Attenuation Rates In Non-Custom Earplugs, Skyler M. Shipley

Dissertations, Theses, and Capstone Projects

Recreational and social environments frequently expose individuals to high intensity noise environments; however, the use of hearing protection devices (HPDs) remains limited. This study evaluated whether non-custom, over-the-counter musicians’ earplugs provide attenuation consistent with manufacturers’ claims and whether cost is associated with performance. Six commercially available earplug models were tested using both human participants and a KEMAR manikin system. Attenuation was measured across frequencies from 250–8000 Hz (octave and inter-octave frequencies) and were tested using different ear tip sizes. Results indicated that several earplugs achieved attenuation levels comparable to or exceeding their advertised noise reduction ratings (NRR), though consistency varied …

Race And The Enduring Logic Of Exclusion In U.S. Immigration Policy, 1882–2025, Kejda Nikollaj

Dissertations, Theses, and Capstone Projects

This thesis examines how immigration law in the United States has historically functioned as an instrument of racial exclusion and argues that this logic continues to shape contemporary policy and enforcement. Although overtly racist laws such as the Chinese Exclusion Act (1882) or the National Origins Act (1924) have long been repealed, their underlying rationales and structures continue to survive under the modern language of legality, security, and national interest. This study argues that restrictive immigration policies tend to emerge when racial and social insecurities intersect, allowing old hierarchies to be revived under new legal justifications. Through a comparative historical …

Gremlin Theory: A Film Art Of Joe Dante, Frank Falisi

Dissertations, Theses, and Capstone Projects

This thesis seeks to establish the work of the filmmaker Joe Dante as a catalyzing and anarchic force let loose inside larger, dumber superstructures: linear narrativity, Hollywood, America, etc. It works to read the genre films he worked on—many of them made as popular entertainment for mainstream movie studios—as moments of actual subversion, allocating status quo (studio system) resources to create a biting-back against American imperial norms in the lingua franca of Marx and the Marx Brothers: gummy leisure-seeking stupidity and Gremlin transformation. This thesis seeks to argue that to understand Dante’s work is to understand pop transfiguration itself. This …

Mapping Nucleosome Stability: Linking Oncogenic Structural Alterations To Long-Range Allosteric Communication, Augustine C. Onyema

Dissertations, Theses, and Capstone Projects

The nucleosome core particle (NCP) is essential for chromatin structure and function, serving as the fundamental unit of eukaryotic chromatin. Oncogenic mutations in core histones disrupt chromatin dynamics, altering DNA repair and transcription processes. How DNA communicates with histones, and how this information propagates through the histone, has been suggested to be a cooperative process. Here, I investigate the molecular consequences of two mutations, H2BE76K and H4R92T, using 36 µs of all-atom molecular dynamics simulations on Anton2. I also characterize the kinetic correlation within histone/DNA domains via conditional activity (CONDACT) using the dihedral angle as our degrees of …

The Exception: Refugee Camps And Governmental Control, Kyle L. Mans

Dissertations, Theses, and Capstone Projects

This capstone study examines the relationship between governmental control and the state of exception in refugee camps. This connection is analyzed by examining the control mechanisms employed by the nation state to erode the sovereignty of the individual within a refugee camp space. This study also examines how humanitarian organizations contribute to the perpetuation of the state of exception and how their involvement facilitates further state control. Included in this capstone are two case studies that examine both Libya and Kenya as examples of governmental control on the sovereignty of refugees and migrants. This research contributes to the overall understanding …