Digital Commons Network^™

Leveraging Mammal Mycophagy To Determine Environmental Drivers Of Truffle Diversity, Brittany Hartsock

Electronic Theses and Dissertations

Many mycorrhizal fungi are hypogeous (truffle-forming), producing underground fruiting bodies. Studying truffles is inherently challenging due to their hidden nature. However, mycophagous mammals provide a unique opportunity to study hypogeous fungi because they rely on truffles as a food source. Although several truffle species have recently been described in the southern Appalachian region, their fruiting patterns remain poorly understood. To address this, we quantified truffle richness and spore loads from 670 Peromyscus scat samples collected across 42 sites spanning an environmental gradient during 2024 in the Blue Ridge Mountains of East Tennessee. We found that truffle richness and spore abundance …

Exploring Competitive Dynamics Between Pseudomonas Baetica And Salmonella In A Polymicrobial System, Braxton E.M. Stout

Electronic Theses and Dissertations

The global rise in antimicrobial resistance has catalyzed a greater focus on polymicrobial research aimed at characterizing microbial interactions and uncovering new therapeutic strategies. Though it has long been of interest, environmental soil-derived bacteria remain largely under-represented in research and thus uncharacterized in this field. This project aimed to identify soil microbes that display inhibitory mechanisms to potential nosocomial pathogens. Soil sample S1S3-2 displayed inhibitory phenotypes toward numerous bacteria and was identified as Pseudomonas baetica. In both planktonic and biofilm growth, P. baetica was able to inhibit Salmonella arizonae through a contact-dependent and temperature-dependent manner. Screening of a transposon insertion …

Phytochemical And In-Vitro Cytotoxic Analyses Of Flavonoid Species Isolated From Chromolaena Leivensis, Luke A. Bryant

Electronic Theses and Dissertations

As a leading cause of death worldwide, cancer and its treatments remain a primary source of interest among researchers. Modern studies are looking into bioselective cytotoxicity to create new chemotherapies that do not have the same harsh side effects as those we use today. Natural product research has a promising future for the development of such treatments. Specifically, polar flavonoids may be the key to a bioselective treatment. Such flavonoid species are native to plants, often within flower petals or within the body. A natural antioxidant, they are designed not to harm healthy cells. This study focuses on the plant …

"Please Put The Phone Down!": Self-Determination Theory Applied To Parental Social Media Mediation, Benjamin A. Dolowich

Dissertations

The majority of adolescents and young adults use social media (Chaddock, 2024; Coyne et al., 2013). Parents are faced with the challenge of considering the role social media may play in their children’s lives (Valkenburg et al., 2013). Using self-determination theory as a framework (Deci & Ryan, 2000), we investigated psychological needs as one mechanism connecting parental social media mediation strategies with well-being and emotional distress in a sample of young adults. Participants were 244 undergraduate students who completed online questionnaires. The results highlighted that controlling styles of parental social media mediation have an association with emotional distress. Psychological needs …

A Critical Review Of Pharmaceutical Pollutants In Soil And Air: Ecotoxicological Impacts On Animal, Plant And Microbial Communities - Health Hazards And Waste Management, Md Faisal Amin, Md. Saydur Rahman

School of Integrative Biological & Chemical Sciences Faculty Publications

Pharmaceutical contamination in soil and air has become a critical environmental concern due to its widespread sources, complex behavior, and long-lasting ecological impacts. This review comprehensively explores the presence, fate, and effects of pharmaceutical compounds in soil, highlighting their entry routes, environmental persistence, and biological consequences. Pharmaceuticals infiltrate terrestrial and aquatic environments through various pathways, including agricultural application, pharmaceutical manufacturing waste, sewage sludge, hospital and household discharges, irrigation with contaminated water, and atmospheric deposition. A wide range of drug classes, such as antibiotics, analgesics, non-steroidal anti-inflammatory drugs, antidepressants, anticancer drugs, and hormones, have been identified in both soil and air …

Wildfire And Fuel Treatments In Utah: A Practical Guide And Outcomes From An Oak-Maple Ecosystem, Annie E. Prescott

All Graduate Theses and Dissertations, Fall 2023 to Present

Wildfire is a natural part of Utah’s landscapes, but as wildfires become more extreme and communities continue to expand into wildland areas, it is increasingly important to understand how wildfires behave and how their negative effects can be mitigated. One way to reduce wildfire risks and protect life, property, and ecosystem services is through fuel treatments — actions that reduce the amount and arrangement of flammable vegetation through mechanical removal, wildland fire, or other methods.

Information on wildfire behavior and fuel treatments is abundant but often scattered, ecosystem-specific and difficult to access. In addition, most research in the Western U.S. …

The Willing And The Compelled: How Power And Place Shape Human-Bison Coexistence In Poland And The United States, Patrick Orville Kelly

All Graduate Theses and Dissertations, Fall 2023 to Present

Wildlife recovery programs depend not just on animals, but on how people feel about living with them. The degree to which people accept the disruptions wildlife brings to their lives, known as social tolerance, can determine whether a recovery program succeeds or fails, yet it remains understudied and underapplied in management plans. This dissertation studies how people in Poland and the western United States feel about living with the two living species of bison, the largest land animals in Europe and North America. In Poland, we surveyed 242 residents living at different distances from European bison habitat. Surprisingly, the most …

Balancing Root-Zone Oxygenation And Rhizosphere Stability: The Impact Of Aeration And Hypoxia On Hydroponic Plant Growth, Christian D. Baker

All Graduate Theses and Dissertations, Fall 2023 to Present

As the global population and food demand continue to increase, growers must look to innovative and sustainable methods for plant cultivation. Hydroponics is a popular method of sustainable plant cultivation where plant roots are suspended over a liquid nutrient solution. Hydroponics uses less water compared to traditional agriculture because there is no evaporation or solution runoff. It also maximizes land use, requires fewer pesticides and herbicides, and enables year-round cultivation in controlled environments. However, indoor hydroponic systems rely on artificial lighting, which has higher energy costs than traditional farming methods. Optimizing growing conditions is therefore critical to ensure long-term economic …

A Global Image-Based Data Repository Of Killer Whale Interactions With Elasmobranchs, Emma Luck, Isabella L. Reeves, Maeva Terrapon, Rebecca Wellard, Stephanie K. Venables, Alison V. Towner, Alison A. Kock, Charlotte Hussain, Molly Altschwager, Rosie Ballard, Evans Baudin, Nancy Black, Evan Brodsky, Jade Cantrall, Julio Cardoso, Matt I.D. Carter, Oliver Clarke, Santiago Diaz-Pazmino, David Donnelly, Georgina Cabayol Ferraz, Arlaine Francisco, Laura González García, Mark Jackman, Aimee Jan, Eric Martin, Dane Mcdermott, James Moskito, Blair Ranford, Jesús Erick Higuera Rivas, Jasmin O’Brien, Anton Oleynik, Hernán Orellana-Vásquez, Daniela Alarcón Ruales, Gemma Sharp, Jade Sharp, Alisa Schulman-Janiger, Colleen M. Talty, Paul Tixier, John A. Totterdell, Steve Truluck, Jennah Tucker, Tara Weberg, M. Fernanda Urrutia-Osorio, Machi Yoshida, Jochen R. Zaeschmar, Lauren Meyer

Research outputs 2022 to 2026

Killer whales (Orcinus orca) are cosmopolitan apex predators that interact with numerous species, including sharks, skates, and rays (subclass Elasmobranchii). Interactions between killer whales and elasmobranchs have garnered attention from the scientific community, but the dynamics of these events are poorly understood, as interactions are often challenging to observe. In this study, we collated imagery of interactions between killer whales and elasmobranchs to create the first image-based repository of interspecific interactions between marine predators. A total of 320 photos and videos from 82 unique interactions were collected from 12 countries. A minimum of 18 elasmobranch species across 16 genera were …

Radio Frequency Tagging–Enabled Patient Monitoring: Integrating Mobility Tracking With Early Warning Systems For Enhanced Safety, Ahed Abugabah, Prashant Kumar Shukla, Piyush Kumar Shukla, Abhishek Dwivedi

All Works

Ensuring patient safety in healthcare environments requires continuous monitoring systems capable of identifying early warning signs of clinical risk. Traditional surveillance methods often fail to capture meaningful patterns in patient movement, limiting their ability to prevent incidents such as falls, prolonged immobility, or unnoticed health deterioration. Radio Frequency Tagging technology has been increasingly adopted for real-time patient tracking; however, existing systems are generally limited to location detection and lack predictive insights into patient behaviour. To overcome these limitations, this study presents a Radio Frequency Tagging-based patient monitoring framework that integrates mobility tracking with an early warning mechanism to enable proactive …

Mtorc2-Nav1.2 Signaling Drives Early Hyperexcitability In Alzheimer’S Disease Mouse Model, Nolan M Dvorak, Jeffrey L Noebels

Faculty, Staff and Students Publications

Hyperexcitability is a biomarker of early-stage Alzheimer’s Disease (AD) and hastens cognitive decline later in its course. Mechanistic target of rapamycin (mTOR) signaling contributes to the slope of this trajectory, as evidenced by early increased brain expression and the rescue of hyperexcitability by genetic deletion of mTOR complex 2 (mTORC2); however, a molecular mechanism directly linking mTOR signaling to membrane hyperexcitability in early-stage AD remains elusive. Here, we show that hyperactive mTOR signaling stimulates the voltage-gated Na+ channel 1.2 (Nav1.2), a previously identified downstream phosphorylation target of mTORC2 and a key regulator of membrane electrogenesis. Augmented Nav1.2 channel function induced …

Long-Term Analysis Of Pm2.5 Elemental Composition And Source Contributions In Coastal Urban Environments Of Corpus Christi And Houston In Texas, Sai Deepak Pinakana, Jeremy A. Sarnat, Amit U. Raysoni

School of Earth, Environmental, & Marine Sciences Faculty Publications

Long-term assessments of fine particulate matter play a key role in identifying persistent and emerging emission contributors. Coastal urban areas are highly susceptible to transboundary dust and wildfire events in addition to local pollution sources. Multi-decadal assessments in these regions using chemical speciation data could offer insights into major pollutant sources and their trends. This study utilizes nearly two decades of PM2.5 elemental composition data at two major coastal cities in Texas: Houston and Corpus Christi. Fourteen trace elements were analyzed to characterize the seasonal variability and long-term source evolution using a combination of Spearman’s correlation analysis, principal component analysis, …

Evaluating The Transformation Of Land Cover, Land Surface Temperature, And Urban Heat Island In Sylhet Division Through Geospatial Analysis, Md Fazle Rabbi Joy, Md Abdur Rahim, Md Mahfuzar Rahman, Sumiaya Amin Preota

School of Earth, Environmental, & Marine Sciences Faculty Publications

Rapid and unplanned urbanization has significantly transformed land use/land cover (LULC), contributing to increased land surface temperature (LST) and the emergence of urban heat islands (UHIs), especially in ecologically fragile regions. This study focuses on the Sylhet Division of Bangladesh, assessing LULC changes, LST dynamics, and UHI expansion from 1994 to 2024 using Landsat satellite imagery, normalized difference vegetation index (NDVI), normalized difference water index (NDWI) indices, and field-based LST validation. Unsupervised classification reveals a 191.75% increase in settlement areas and a 25.65% loss in forest cover. Correspondingly, the highest LST zones (> 30 °C) were absent in 1994 but …

In-Hospital Mortality Patterns And Readmissions In Patients With Chronic Obstructive Pulmonary Disease: An Analysis Of The Role Of Pulmonary Hypertension, Saad Afzal Khan, Trishna Parikh, Adishwar Rao, Akriti Agrawal, Aarohi Parikh, Farah Kazzaz, Sarah Shin, Harry Karmouty-Quintana, Maulin Patel, Kha Dinh, Bela Patel, Bindu Akkanti

Faculty, Staff and Student Publications

Chronic obstructive pulmonary disease (COPD) may be complicated by pulmonary hypertension (PH). We aimed to understand the impact of PH on in-hospital mortality and quantify the 30-day readmission rate among patients with COPD. For this cross-sectional study, we used the Nationwide Readmissions Database from 2017-2020 to identify adults ≥18 years with COPD. Patients were stratified according to PH diagnosis. Baseline characteristics between groups were compared using the Pearson chi-square test and two-sample t-test. Predictors of in-hospital mortality were determined using multivariate logistic regression analysis adjusted for demographics and confounders. The 30-day readmission rate and prevalence of PH subgroups by baseline …

Methylated Cfdna May Distinguish Between High- And Intermediate-Risk Uveal Melanoma: A Pilot Study, Mike Wu, Daniël P. De Bruyn, Ruben G. Boers, Aaron B. Beasley, Daan M. Hazelaar, Stavros Makrodimitris, Joachim B. Boers, Jolanda Vaarwater, Ronald O.B. De Keizer, Robert M. Verdijk, Nicole C. Naus, Dion Paridaens, Saskia M. Wilting, Elin S. Gray, Wilfred F.J. Van Ijcken, Joost Gribnau, Annelies De Klein, Erwin Brosens, Emine Kiliç

Research outputs 2022 to 2026

Background: Uveal melanoma (UM) is a highly aggressive malignancy with a metastatic risk that depends on the molecular subclass. This subclass can be determined through molecular characterization of tumor-derived tissue. With eye-sparing treatments, tumor tissue is rarely available for molecular testing. We hypothesized that minimal invasive biomarkers such as methylated cell-free DNA (cfDNA) or circulating tumor DNA (ctDNA) can be used for prognosis and monitoring of patients. Methods: Plasma cfDNA was isolated from healthy blood donors (HBDs, N = 19) and UM patients (N = 22). Plasma was collected at baseline (localized disease, N = 13) and during follow-up (metastatic …

Climate Change Impacts On Fish-Related Ecosystem Services: Synthesis, Network Analysis, And Strategic Pathways For Coordinated Adaptation, Ebenezer Afrifa-Yamoah, Awuah-Mensah, Stephen Bradshaw, Ute Mueller

Research outputs 2022 to 2026

Climate change is rapidly disrupting fish-related ecosystem services that underpin global food security, economic livelihoods, and cultural identity across both marine and freshwater systems. While impacts are increasingly recognised, disciplinary fragmentation has hindered integrated understanding of how climate-driven changes in fish populations affect ecosystem service delivery. This review makes two integrated contributions: a hierarchical synthesis tracing causal pathways from physical climate drivers through biological and ecological responses to socioeconomic outcomes, and a qualitative network analysis that maps the interconnections, implementation readiness, and strategic sequencing of seven major adaptation strategies. Ocean warming, acidification, deoxygenation, and their increasingly frequent co-occurrence as compound …

Design Of Automatic Security System Based Internet Of Things At The Museum, Rahmat Ageng Yuwana, Nuryake Fajaryati, Ferry Jie

Elinvo (Electronics, Informatics, and Vocational Education)

This research aims to determine the procedures for developing an Internet of Things (IoT)-based Automatic Security System as a security device for museum objects and to test its feasibility based on user feedback in museums. The Design Thinking model used consists of five stages: Empathize (understanding the user’s perspective), Define (gathering information on the encountered problems), Ideate (generating innovative ideas), Prototype (creating a prototype of the obtained ideas, ensuring the functionality of each device feature, and validating the product through expert judgment for feedback and product revision), and Testing (evaluating the system’s feasibility using Usability standards based on ISO/IEC 9241-11, …

Caribou Migration And Non-Local Hunting In Northwest Alaska: A Gis Analysis Of Hunting Activity And Its Relationship With Caribou Migration Corridors, Brittney L. Jiménezszabo

Geography and the Environment: Graduate Student Capstones

Indigenous Alaskans rely on subsistence hunting for food, with Barren-ground caribou making up approximately 27% of their diet. It is believed by subsistence hunters that non-local hunting is forcing a change in caribou migration behavior. This study examined non-local harvesting records from 2013 – 2025 in the northwest and interior Game Management Units (GMU) and Alaksa’s Western Arctic Caribou Herd (WACH) migration range data to answer the question, is there a spatial relationship between non-local harvests and WACH migration behavior. Mixed methods included spatial autocorrelation and local statistics. Findings led to the rejection of the null hypothesis which will help …

Lithium Titanate-Functionalized Mixed Matrix Polymer Membrane For High-Performance Osmotic Energy Conversion, Rockson Kwesi Tonnah, Yasaman Boroumand, Milad Razbin, Mostafa Vahdani, Amir Razmjou, Mohsen Asadnia

Research outputs 2022 to 2026

Reverse electrodialysis (RED) offers a promising route to harvest osmotic energy from salinity gradients, yet practical implementation is hindered by the lack of scalable, high-performance ion-selective membranes that combine efficient ion transport with mechanical robustness and environmental sustainability. Here, we report a mixed matrix membrane composed of polyethersulfone (PES), polyvinylpyrrolidone (PVP), and lithium titanium oxide (Li₂TiO₃, LTO) that addresses these challenges through biomimetic ion transport channels. The strategic integration of LTO nanoparticles introduces ion-exchange sites and oxygen-rich PES ether linkages to create preferential cation transport pathways that mimic biological ion channels. This mixed matrix design delivers over three-fold cation conduction, …

Development Of A Culture System For Eosinophils Derived From Human Cord Blood Stem Cells, Christian Lachance

Summer Research Program Abstracts

No abstract provided.

Acceleration Of Coagulation Kinetics For Clot Burst Pressure Assessment, Hanuk Kwon

Summer Research Program Abstracts

No abstract provided.

Emotional Urgency And Lack Of Perseverance Are Linked To Anxiety Sensitivity And Improve During Early Recovery From Opioid Use Disorder., Breanna A. Mcnaughton-Long, Abigail J. Pleiman, Carmen Buchfink, Chrysantha B. Davis, Rayus Kuplicki, Martin P. Paulus, Hung-Wen Yeh, Maëlle C M Gueguen, Jennifer L. Stewart

Manuscripts, Articles, Book Chapters and Other Papers

Few studies have identified how facets of impulsivity relate to recovery in opioid use disorder (OUD). Treatment-enrolled individuals with OUD (n = 167) and healthy controls (CTL; n = 46) completed the Urgency, Premeditation, Perseverance, Sensation Seeking, Positive Urgency (UPPS-P) Impulsive Behavior Scale along with demographic and clinical measures at visit 1. Over the next three months, abstinence and return to use were documented for participants with OUD (via self-report, alcohol breathalyzer, urine drug screen, and secondary contact communication). Participants with OUD who returned to use (n = 59) did not complete further study visits, whereas those who remained abstinent …

Managing Collaboration Under Conservation Crisis: Trust, Risk, And Control In The Gulf Of Maine Fishery Management Network, Evelyn Roozee, Owen Temby, Dongkyu Kim, Antonia Sohns, Anthony Rocha Lima, Jasper R. De Vries, Gordon M. Hickey

School of Earth, Environmental, & Marine Sciences Faculty Publications

Transboundary fishery management and the intertwined conservation of critically endangered species represent significant governance challenges that require ongoing inter-organizational communication, collaboration, and collective action to achieve shared objectives. Previous research suggests that inter-organizational collaborative performance depends heavily on different dimensions of trust and complementary control mechanisms to mitigate the perceived risks of collaborating and enable the reciprocal sharing of resources and the coordination of activities. However, it is unclear how proposed relationships between trust, risk, and control are shaped by disruptions to established transboundary management networks. This study presents the results of survey research conducted in the Gulf of Maine …

Fall 2026 Environmental Sciences Seminar Series, Sam Bogan, Sam Bogan

NRESS Seminars

The deep sea is Earth's largest and least-explored habitat, leaving much of its biology unknown. I will present two studies leveraging long-read sequencing to uncover the population dynamics and evolution of deep-sea vertebrates. First, we examined how deep-sea invasions constrained thermal adaptation in  globally distributed fishes. Second, we reconstructed the demography and population health of elusive, deep-foraging whales. In these intractable but important systems, advances in long-read sequencing enabled previously unattainable biological insights.

Evaluating Data-Mining Strategies For Label-Free Raman Microspectroscopic Analysis Of Cellular Processes In Vitro: Dynamic Dimensionality Reduction, Zohreh Mirveis, Nitin Patil, Hugh J. Byrne

Research Outputs: 2025-Present

Understanding dynamic intracellular metabolism is essential for elucidating cellular function and disease mechanisms. However, analysing time-resolved spectral data is challenging due to overlapping signals, high dimensionality, and biological variability. This study evaluates the applicability of Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) for resolving complex cellular spectral data and introduces a framework that integrates Principal Component Analysis (PCA) of sequential time points as a preprocessing step. PCA was used to extract dominant spectral variance associated with biological kinetics (PC1), and MCR-ALS was subsequently applied to the sequential PC1 loadings to enhance the recovery of kinetic trends. To validate the approach, simulated …

The Antibacterial Properties Of The Infrapatellar Fat Pad Organ, Mark A. Coggins

Summer Research Program Abstracts

No abstract provided.

Engineering Pegylated Chitosan–Gold Nanoparticles For Radiosensitization And Sirna Delivery To Glioblastoma, Wesley Chiu

Summer Research Program Abstracts

No abstract provided.

Ai-Driven Biomarker Discovery & Progression Modeling For Precision Diagnosis Of Glaucoma, Cheng Huang

Computer Science and Engineering Theses and Dissertations

This dissertation presents a comprehensive study on the integration of artificial intelligence (AI) for glaucoma diagnosis and retinal image analysis. Leveraging multimodal imaging data including fundus photography, Optical Coherence Tomography Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA), the research develops a suite of deep learning frameworks designed to detect early glaucomatous changes with high precision, robustness, and interpretability. A series of novel architectures are introduced, spanning vessel segmentation networks, biomarker discovery pipelines, and multimodal fusion models, all designed to enhance diagnostic accuracy and generalizability across diverse populations. To facilitate reproducible and scalable ophthalmic AI research, this work …

Failed Gay Rights Amendment To Mankato's Human Rights Ordinance In Mankato, Minnesota In 1987, Kellian Clink

Library Services Publications

In 1987, small but passionate people urged the city to pass an amendment to Mankato’s existing human rights ordinance to protect LGBTQ+ communities.   Advocates argued that gays were entitled to the same rights as straight people and were looking for protection in housing and employment, particularly. They demonstrated that people had lost jobs, housing, and access to dance venues. Some opponents equated gays with promiscuity, child molestation, solicitation, sin, and AIDS; some were convinced it was not needed; some pinned their arguments on the existence of laws already on the books.  This narrative is based on articles from the local …

Bile Acid Metabolites And Carotid Intima Media Thickness In The Chronic Kidney Disease In Children (Ckid) Study., Arthur M. Lee, Mark M. Mitsnefes, Jennifer Roem, Bradley A. Warady, Susan L. Furth, Michelle R. Denburg, Ckid Study Investigators

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.