Digital Commons Network^™

Seasonal Molecular And Secretory Responses Of Equine Ovarian Follicles To Estradiol And Sulpiride Treatment, Madalyn Autin

LSU Master's Theses

Mares entering seasonal anovulation during winter present a significant challenge for equine breeding programs. Treatment with estradiol cypionate (ECP) and sulpiride in a long-acting vehicle can advance the first ovulation of the season; however, the molecular and secretory mechanisms underlying this response remain unclear. This study compared follicle wall gene expression and endocrine factors (from blood plasma and follicular fluid) among seasonally anovulatory mares responding to ECP-sulpiride (RESP; n = 15, treated with 50 mg ECP and 3 g sulpiride), mares undergoing natural spring transition (ST; n = 16, vehicle-treated only), and mares cycling during the summer ovulatory season (SOV; …

Kinds Of Evidence Cited By Councilors In Municipal Council Sessions: The Case Of Santa Fe, Cebu, Philippines, Junald D. Ango

Journal of Public Affairs and Development

This paper explores the practice of evidence-based policymaking (EBPM) in the municipal council of Santa Fe, Cebu, Philippines. Data for this study is based on a content analysis of the minutes of council sessions and committee meetings from July 2022 to August 2024. The use of evidence in policymaking has caught on among policymakers in the Philippines, at both the national and local levels. However, few studies have examined policymakers' use of evidence in municipal governments, especially those in smaller, less urbanized towns. In the case of the Municipality of Santa Fe, at least 13 kinds of evidence were cited …

Interstitial Fluid N-Glycans Serve As A Proxy For Serum Biomarker Discovery In A Pilot Study, Radka Saldova, Talus K. Gaymore, Caitriona Walsh, Eder Zavala, Paula M. Mendes

Student Papers, Posters & Projects

Protein glycosylation is the most prevalent post-translational modification and is known to undergo profound alterations in disease. While serum N-glycosylation has been extensively studied, interstitial fluid is gaining prominence as a minimally invasive biomarker source, underscored by the widespread clinical adoption of wearable glucose monitors in diabetic patients. However, the glycomic landscape of interstitial fluid remains largely unexplored. Here, we have performed a comparative analysis of the N-glycome from interstitial fluid and matched plasma from five healthy volunteers using liquid chromatography, mass spectrometry and exoglycosidase digestions. Strikingly, the interstitial fluid N-glycome closely shows overlapping profiles with the plasma of each …

Analysis And Categorization Of Second-Order Linear Partial Dynamic Equations On Time Scales, Svetlin G. Georgiev, Jervin Zen Lobo, Sanket Tikare

Turkish Journal of Mathematics

In this paper, we obtain the canonical form of second-order linear partial dynamic equations in two independent variables on time scales, together with the identity for the characteristic quadratic form. This is then used to classify these equations as hyperbolic, elliptic, or parabolic. We deduce the characteristic equations in each case, determine their roots, and provide the corresponding characteristic curves. In one case, we derive the generalized Beltrami equations on time scales. Suitable examples involving equations of interest are explored, and the developed theory is illustrated through these examples.

A Modest Proposal For Discourse Analysis In Nonbinary Communities: Method And Case Study, Nikoli Michael Daigneault

Electronic Theses and Dissertations

While linguists have long used discourse analysis to study language variation in binary and nonnormative gender groups, nonbinary people have often been excluded from analyses or treated without a nonbinary-informed framework. Nevertheless, nonbinary language use can provide key insights into the relationship between gender and language. In this thesis, I propose Nonbinary Discourse Analysis, a set of recommendations and best practices for conducting discourse analysis in nonbinary communities. These methods are informed by previous empirical research on nonnormative gender identities and theoretical work in trans linguistics (Zimman, 2020) and trans epistemologies (Nordmarken, 2019; Raclaw, in press). To demonstrate the methodology, …

Mechanistic Determination Of Host Environmental Impacts On Shigella Virulence, Nicholas E. Dickenson

Funded Research Records

No abstract provided.

Transcriptomic And Genomic Insights Into Nutrient Stress Responses And Subgenome Evolution In Chenopodium, Ashley Kathleen Marcheschi

Theses and Dissertations

Chenopodium is a diverse genus of nutritionally and ecologically important species in the Amaranthaceae family. This thesis investigates two outstanding questions in the genus: how Chenopodium quinoa responds transcriptionally to nutrient deficiency and how Australian Chenopodium species are related through their subgenomic ancestry and evolutionary history. First, we characterized transcriptomic responses of C. quinoa to deficiencies of twelve essential macro- and micronutrients across leaf and root tissues using RNA sequencing. Leaves showed the strongest responses under nitrogen, potassium, magnesium, and zinc deficiency, while roots responded more evenly across conditions. Recurring responses included suppression of photosynthesis, remodeling of translational machinery, reactive …

Residual Effects Of Childhood Sexual Victimization On Black Caribbean Immigrants’ Adult Functionality, Sophia Elaine Profit

Walden Dissertations and Doctoral Studies

Childhood sexual victimization is associated with long-term psychological, emotional, and functional challenges that may persist into adulthood. Despite a growing body of literature on childhood trauma, limited research has explored its residual effects on adult functionality among Black Caribbean immigrants. The purpose of this qualitative phenomenological study was to explore the residual effects of childhood sexual victimization on adult functionality among Black Caribbean immigrants. Purposive and snowball sampling were used to recruit 9 participants through social media platforms. Rational choice theory served as the conceptual framework to examine how trauma-related and sociocultural factors shaped participants' decision-making processes. Data were collected …

Food And Drug Administration Audit Outcomes And Their Association With Class I And Class Ii Food Recalls, Mark Baker

Walden Dissertations and Doctoral Studies

Foodborne illness and food recalls remain major public health concerns in the United States. Guided by the Theory of Planned Behavior, the purpose of this quantitative secondary analysis was to examine whether Food and Drug Administration (FDA) inspection classifications, warning letters, and prior 24-month inspection frequency were associated with facility involvement in a subsequent Class I or Class II food recall. Question-specific analytic files were created from publicly available FDA administrative records. Eligible records included FDA-regulated food facilities with qualifying inspection or warning letter events and sufficient data to assess recall involvement within a 12-month follow-up period. The final analytic …

Perceived Level Of Preparedness For A Terrorist Event Between State, Local And Tribal Law Enforcement Officers, Herbert Henderson

Walden Dissertations and Doctoral Studies

In this quantitative cross-sectional study, differences in perceived preparedness among state, local, and tribal law upon Kingdon’s multiple streams approach and Baumgartner and Jones’ punctuated equilibrium theory to explain administrative changes in law enforcement following the September 11, 2001, attacks. Data were collected from 53 full-time police officers across state, local and tribal agencies using a web-based survey instrument measuring enforcement officers in a northern border region were examined. Officers’ perceived preparedness to identify, prevent, and respond to future terrorist threats were evaluated. Whether perceived preparedness differed by agency type and whether officers with military experience or advanced homeland security …

Neurofilament Light Chain (Nfl) As A Surrogate Outcome Measure For Gm2 Gangliosidoses., Kyriakos Martakis, Nicolas J. Abreu, Joshua J. Baker, Peter R. Baker Ii, Ian Billington, T Andrew Burrow, Mallory Factor, Taylor Fields, Cassandra Fields, Jennifer L. Gannon, Megan Grosso, Jorgji Kerthi, Marc C. Patterson, Brian J. Shayota, Michael Strupp, Lennard Strupp, Tatiana Bremova-Ert

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: The GM2 gangliosidoses (GM2) are ultra-rare neurodegenerative disorders caused by deficient hexosaminidase A and/or B activity, leading to lysosomal GM2 ganglioside accumulation. Disease onset ranges from infancy to adulthood, with earlier onset associated with more rapid progression. Neurofilament light chain (NfL), a sensitive marker of axonal injury, has been extensively investigated as a biomarker for neurodegenerative disorders, including GM2.

METHODS: To evaluate its clinical utility as a biomarker for GM2, NfL was measured in patients with GM2 enrolled in a Phase 2b, multinational, rater-blinded study of levacetylleucine [NCT03759665], and in its open-label Extension Phase (EP).

RESULTS: Nineteen participants had …

Nitrogen Management Strategies For Specialty Tea Production In Louisiana: Rate, Source Type, And Nutrient Dynamics, Autumn D. Hilderbrand

LSU Master's Theses

Tea (Camellia sinensis L.) is an emerging specialty crop in Louisiana and the southeastern United States; however, region-specific nitrogen (N) management recommendations remain limited. This research evaluated N fertilizer source, application rate, and nutrient leaching to identify management strategies that improve nitrogen use efficiency (NUE) and environmental sustainability during tea establishment.

Three complementary studies evaluated N source replacement, application rate, and fertilizer source effects on nutrient retention and movement. The first study evaluated the replacement of urea ammonium sulfate (UAS) with blood meal (BM) while maintaining a constant annual N application rate. Fertilizer replacement did not significantly affect leaf …

Pharky, Phedro, Phractured, And Stagephright: Complete Genome Sequences Of Four Ek2 Cluster Microbacterium Phages, Susan M. R. Gurney, Medha Gupta, Deeksha Reddy, Gloria Zacharias, Aleda S. Jomy, Carly J. Smith, Matthew T. Mcdonald, Brett M. Condon

Student Papers, Posters & Projects

We report the complete genome sequence of four Microbacterium phages, Pharky, Phedro, Phractured, and StagePhright, isolated using the bacterial host Microbacterium foliorum from soil samples collected in Philadelphia. All four phages are genetically very similar and contain a gene of unknown function, which is uncommon in the EK2 cluster.

Mechanistic Basis Of Bifunctional Oxidation By A Non-Heme Fe(Ii)/2-Oxoglutarate-Dependent Enzyme Cctet Toward N6-Methyladenine And 5-Methylcytosine In Double-Stranded Dna, Bhargav Varada, Simahudeen Bathir Jaber Sathik Rifayee, Midhun George Thomas, Ethan Sommer, Carter Davis, Sodiq Waheed, Sudheesh Devadas, Surajit Kalita, Sreerag Melayikandy, Tatyana Karabencheva-Christova, Christo Christov

Michigan Tech Publications

CcTET (Coprinopsis cinerea ten-eleven translocation) is a non-heme Fe(II)/2-oxoglutarate (2OG)-dependent oxygenase that catalyzes the oxidative demethylation of both N⁶-methyladenine (6mA) and 5-methylcytosine (5mC) in double-stranded DNA, distinguishing it from other TET enzymes that act exclusively on 5mC. Despite this bifunctional activity, the molecular origins of its substrate selectivity and catalytic mechanism remain poorly understood. Here, we employed a multiscale computational approach combining classical molecular dynamics simulations and hybrid quantum mechanics/molecular mechanics calculations to characterize the conformational dynamics and reaction pathways of CcTET. Our results show that CcTET follows the canonical Fe(IV)=O-mediated mechanism, in which hydrogen atom transfer (HAT) …

Less Frequent Versus More Frequent Cervical Examinations In Labor: A Systematic Review And Meta-Analysis, Alessandro Petrecca, Benedetta Bina, Chiara Tersigni, Tullio Ghi, Vincenzo Berghella

Department of Obstetrics and Gynecology Faculty Papers

BACKGROUND: Digital cervical examinations are central to intrapartum care, yet their optimal frequency remains uncertain and is largely based on consensus rather than high-quality evidence.

OBJECTIVES: To compare less frequent versus more frequent cervical examinations during labor in terms of obstetrical, maternal and neonatal outcomes.

SEARCH STRATEGY: We searched Medline, Cochrane Library, EMBASE, PubMed Central, Scopus and ClinicalTrials.gov from inception to August 2025, without language or geographic restrictions. The review was registered in PROSPERO (CRD420251033729).

SELECTION CRITERIA: Randomized controlled trials comparing different frequencies of cervical examinations in term singleton pregnancies during labor were included.

DATA COLLECTION AND ANALYSIS: Two reviewers …

Movement And Distribution Dynamics Of Predatory Fishes In The St. Lucie Estuary, Sarah Fae Leonowicz Torre

Electronic Theses and Dissertations

Estuaries are productive but highly variable ecosystems that support recreationally and commercially valuable fisheries, as well as species of conservation concern. However, coastal development, habitat loss, altered freshwater inflow, and declining water quality can modify the environmental gradients that structure fish distributions. In the St. Lucie River and southern Indian River Lagoon, located in southeast Florida, managed freshwater discharges, watershed runoff, shoreline modification, and degradation of essential fish habitats (e.g., seagrass, oyster, and mangrove forests) have altered estuarine conditions.

This dissertation evaluates how four estuarine fish species with contrasting life histories respond to environmental variability, hydrologic disturbance, and habitat structure …

Explainable Machine Learning For Biomedical Diagnostics: Optical Imaging And Eeg Signal Analysis, Fozia Rajbdad

LSU Doctoral Dissertations

The growing convenience of complex biomedical data begins new roads for better disease detection and functional identification via artificial intelligence (AI). Nevertheless, conventional analysis methods often rely on basic metrics that drop sensitive biotic differences, and various AI systems are difficult to infer, limiting their clinical reliability and practical use. There is a growing need for explainable, physiologically relevant computational models that can extract key biomarkers from diverse biomedical data sources. This dissertation addresses this problem by obtaining explainable machine learning and deep learning procedures for studying biomedical signals and optical imaging data.

This dissertation is divided into two parts; …

The Association Between Ferritin Marker And Iron Deficiency Anemia In Peptic Ulcer Disease Patients: A Case-Control Approach, Sajjad Fadhil K. Abbas, Abeer Cheaid Yousif Al-Fatlawi, Ahmed Hashim Abbas Al-Janabi

Al-Ameed Journal for Medical Research and Health Sciences

Background: Peptic ulcer disease refers to deep erosions in the mucosal layer of the GIT and is highly associated with upper gut bleeding, which results in anaemia. Ferritin is a protein that stores iron in the body.

Aim: To estimate serum ferritin levels in relation to anaemia in peptic ulcer disease and assess its potential as a predictor of peptic ulcer bleeding.

Method: A case-control study in Kerbala, Iraq, measured ferritin by ELISA and anaemia by Hb levels on CBC, with ROC curves used to assess sensitivity and specificity.

Results: results show a significant difference in haemoglobin and ferritin levels …

Deciphering The Potential Of Monopterus Albus Protein Hydrolysate As A Therapeutic Candidate Against Cervical Cancer By Integrating Content Analysis, Network Pharmacology, And Molecular Docking, Okid Parama Astirin, Widya Mega Rahmawati, Elisa Herawati, Tetri Widiyani, Lili Pandan Sari, Sherly Octaviana

Karbala International Journal of Modern Science

Cervical cancer has a high incidence rate in women, making the development of cancer drugs increasingly urgent. Asian swamp eel protein hydrolysate shows great promise as an anticancer candidate. This study aimed to reveal the potential of Asian swamp eel protein hydrolysate as an anticancer candidate in the cervix. Asian swamp eel protein hydrolysate was produced by hydrolyzing flesh with the enzyme alcalase. Compounds and peptides were identified using LC-HRMS. These compounds and peptides were analyzed using network pharmacology, gene ontology, and molecular docking. The results identified 153 endogenous compounds, including fatty acids and peptides. The key proteins targeted by …

Compressed Cinema As A Study In Llm Latent Spaces, Mallen Clifton

ELO (un)supervised 2026

In his article “Spec Acts” (2021), Matthew Kirschenbaum analyzes the AI-generated novel 1 the Road to develop his titular concept of the spec act, “the future in its multitudes collapsing into an actionable present.” With the proliferation of texts produced by generative AI and subsequent critical analyses of them, one element in particular calls for further theorization: “the future in its multitudes,” or more directly, the latent space. This echoes arguments by critics such as Antonio Somaini, who offered his own “Theory of Latent Spaces” last year. However, where Somaini’s attention is towards visual culture, I turn mine to the …

Mississippi's Contribution To The Anti-Evolution Movement, R. Halliburton Jr.

Journal of Mississippi History

No abstract provided.

The State Of The Child In Tennessee 2023, Tennessee. Commission On Children And Youth.

The State of the Child in Tennessee

No abstract provided.

Kids Count The State Of The Child In Tennessee 2019 Policy And Issue Guide, Tennessee. Commission On Children And Youth.

The State of the Child in Tennessee

No abstract provided.

Coordinated Operation Of Electrically Heated Reverse Water-Gas Shift Reactor With Time-Dependent Carbon Dioxide Source, Martin Baumgaertl, Gianluca Pauletto

Defensive Publications Series

The present technical disclosure relates to a plant and to a corresponding process for the operation and control of an electrically heated reverse water gas shift reactor, which is supplied with a carbon dioxide stream preferably originating from a biogas production unit and hydrogen stream preferably supplied by an electrolysis unit. The technical disclosure enables flexible operation in accordance with the time-dependent availability of carbon dioxide as a control parameter and allows alignment of electrical energy consumption with the availability of renewable electricity.

Coordinated Operation Of An Electrically Heated Reformer With A Time-Dependent Biogas Feed, Martin Baumgaertl, Gianluca Pauletto

Defensive Publications Series

The present technical disclosure relates to a plant and to a corresponding process for the operation and control of an electrically heated steam methane reformer, which is supplied with a gaseous stream originating from a biogas production unit. The technical disclosure enables flexible operation in accordance with the availability of electrical energy, in particular renewable electrical energy, and the temporal variations in the composition of a gaseous feed, in particular variations in methane concentration and calorific value of a biogas stream.

Plant And Process For Methanol Production From Biogas With Integrated Carbon Dioxide Recycling, Marco Precoma, Martin Baumgaertl, Gianluca Pauletto

Defensive Publications Series

The present technical disclosure relates to a plant and to a corresponding process for the conversion of a biomass feedstock into methanol, wherein both methane and carbon dioxide contained in the biogas are utilized with a high degree of carbon efficiency. The plant integrates an electrically heated reformer and a carbon dioxide separation unit for the internal recycling and utilization of carbon dioxide, in particular by reintroducing at least a portion of separated carbon dioxide into the biogas production unit.

A Comparative Expression Analysis Of Selected Genes Involved In Secondary Metabolites Biosynthesis Among Three Alfalfa Cultivars Grown In Iraq, Izdehar Yahia Obaid, Bushra M. J. Alwash

Al-Bahir

Because of its abundance in proteins, vital amino acids, vitamins, and minerals that promote balanced nutrition, Medicago sativa L., also known as alfalfa, is regarded as a nutritionally excellent forage crop. In addition to its nutritional value, alfalfa produces a range of bioactive secondary metabolites, including flavonoids, alkaloids, and phenolic acids, further supporting its use in medicinal and nutritional applications. Three alfalfa cultivars grown in Iraq were examined for gene expression levels of the primary genes involved in secondary metabolite biosynthesis (PAL, COMT, CHS, and OMT). Among these cultivars are Victoria (VC), Green Gold (GC), and a local cultivar (LC). …

Homocysteine Thiolactone From Translation Proofreading Is An Endogenous Ligand For Cell-Cell Signaling By The Receptor Sdia, Lorenzo Eugenio Leiva, Roberto A. Zúñiga, Gregory J. Phillips, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Several widespread mechanisms enable cellular communication and coordinate the behavior of bacterial populations. The modules responsible for cellular communication are often found in matching pairs: an enzyme that synthesizes a signal molecule and a specific receptor that decodes it. A notable exception is Escherichia coli SdiA, a homolog of known N-acyl-homoserine lactone (AHL) receptors, for which no corresponding AHL synthase exists. SdiA is an orphan receptor that enables cross-talk by sensing AHLs from other bacterial species. In this work, we investigated whether homocysteine thiolactone (HTL), an AHL-like molecule arising from a proofreading reaction of methionyl tRNA synthetase (MetRS) to correct …

Characterizing Mosquito Species To Understand Disease Ecology Of Gyrfalcons In Nome, Alaska, Zosha Kocemba, Annastasia Waters, Michael Henderson, Kara Beer, Travis Booms, Carly Tolle, Anna Grimstein, Stephanie J. Galla

Idaho Conference on Undergraduate Research

Climate change in the Arctic is accelerating more rapidly than the rest of the globe, changing the disease ecology within arctic systems. A prime example of this are disease carrying mosquitoes (Family: Culicidae) expanding their range and overlapping with different animal hosts. To better ascertain the changing disease ecology in the Arctic, methods to identify disease vectors—like mosquitoes—are needed to understand how this complex and shifting vector and host network will impact immunologically naive Arctic Gyrfalcons (Falco rusticolus). This ongoing study aims to identify mosquitoes collected from Gyrfalcon nests in Nome, Alaska to species level and to test …

Phenotypic Plasticity And Transpiration Patterns In Sagebrush Under Controlled Environmental Stress Conditions, Megan Marty, Paige Skinner, Peggy Martinez, Sven Buerki

Idaho Conference on Undergraduate Research

Sagebrush (Artemisia tridentata) is a shrub species native to the sagebrush steppe of western North America. Increasing drought and heat events, along with rising wildfire frequency, place significant stress on sagebrush populations and threaten their long‑term sustainability. Phenotypic plasticity, the ability of an individual plant to modify its physiology during its lifetime in response to environmental stress, may help certain sagebrush genotypes to better tolerate these changing conditions. Phenotypic plasticity does not involve genetic change, although stress triggered physiological modifications may be inherited through epigenetic processes. Plasticity is not universal across sagebrush genotypes. The research in this lab …