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Articles 14581 - 14610 of 18647
Full-Text Articles in Entire DC Network
The Effect Of Macadamia Nut Oil Solution On The Growth Of Saccharomyces Cerevisiae, Yashas Peddireddy
The Effect Of Macadamia Nut Oil Solution On The Growth Of Saccharomyces Cerevisiae, Yashas Peddireddy
Journal of the South Carolina Academy of Science
No abstract provided.
Ultrasonic Extraction-Based Analysis Of Persistent Organic Pollutants In Blubber From False Killer Whales, Michael O. Eze, Eva Borras, Mitchell M. Mccartney, Don R. Bergfelt, Kristi L. West, Sarah E. Hooper, Cristina E. Davis
Ultrasonic Extraction-Based Analysis Of Persistent Organic Pollutants In Blubber From False Killer Whales, Michael O. Eze, Eva Borras, Mitchell M. Mccartney, Don R. Bergfelt, Kristi L. West, Sarah E. Hooper, Cristina E. Davis
Chemistry Faculty Research & Creative Works
In view of the toxic effects of persistent organic pollutants (POPs), fast and effective assessment of their concentrations in marine mammals is important for understanding individual and population-level health impacts. This study developed an ultrasonic-based method that is less time-consuming, uses minimal solvent, and thus is more sustainable than the gold standard Soxhlet method for accurate analysis of organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs), and benzene hexachlorides (BHC) in false killer whale blubber. This method was developed by comparing concentrations of POPs obtained using the traditional Soxhlet and novel ultrasonic extraction methods using blubber from false killer whales (n = …
Tdec 2025 Annual Report, Tennessee. Department Of Environment & Conservation.
Tdec 2025 Annual Report, Tennessee. Department Of Environment & Conservation.
Annual Report
No abstract provided.
Natural Protective Mechanisms Of Cucumis Callosus Leaves In Escherichia Species-Induced Urinary Tract Infection: An Integrated In Silico And In Vivo Study, Meenal Sahu, Tripti Paliwal, Radhika Joshi, Arya Kuhu Vishwapriya, Namita Misra, Smita Jain, Gautam Singhvi, Gulshan Kumar, Devesh U. Kapoor, Dipjyoti Chakraborty, Swapnil Sharma
Natural Protective Mechanisms Of Cucumis Callosus Leaves In Escherichia Species-Induced Urinary Tract Infection: An Integrated In Silico And In Vivo Study, Meenal Sahu, Tripti Paliwal, Radhika Joshi, Arya Kuhu Vishwapriya, Namita Misra, Smita Jain, Gautam Singhvi, Gulshan Kumar, Devesh U. Kapoor, Dipjyoti Chakraborty, Swapnil Sharma
Michigan Tech Publications
Leaves of Cucumis callosus, traditionally employed in Ayurvedic medicine for the treatment of urinary disorders, were investigated in depth for their therapeutic potential against bacterially induced urinary tract infection (UTI) for the first time. The present work is the first to explore the antibacterial activity of C. callosus leaf fractions with an integrative in silico, in vitro, and in vivo approach. Through bioassay-guided fractionation, the chloroform fraction (F1) was identified as the most active, exhibiting potent activity against Uropathogenic Escherichia spp. species. Liquid chromatography–mass spectrometry (LC-MS) analysis of F1 revealed the presence of bioactive compounds, including stigmasterol, 1,2,3,4-tetrahydroisoquinoline, lactose, hydroxy(mesityl)acetic …
First Report Of The Chytrid Fungus, Batrachochytrium Dendrobatidis (Chytridiomycota: Rhizophydiales) From Spring Peeper, Pseudacris Crucifer (Anura: Hylidae), In Western Arkansas, C. T. Mcallister, I. F. Standish, E. M. Leis, M. R. Rodriguez, G. Burrows, H. W. Robison
First Report Of The Chytrid Fungus, Batrachochytrium Dendrobatidis (Chytridiomycota: Rhizophydiales) From Spring Peeper, Pseudacris Crucifer (Anura: Hylidae), In Western Arkansas, C. T. Mcallister, I. F. Standish, E. M. Leis, M. R. Rodriguez, G. Burrows, H. W. Robison
Journal of the Arkansas Academy of Science
Seven adult spring peepers, Pseudacris crucifer, were collected by hand during April 2024 from Polk County, Arkansas, and examined for the pathogens, Batrachochytrium dendrobatidis (Bd), Batrachochytrium salamandrivorans (Bsal), and frog virus 3-like Ranavirus (FV3). Swabs from three of seven (43%) individuals tested positive for Bd: all P. crucifer were negative for the other two pathogens. In addition, no hosts showed any obvious pathological signs of infection and, as such, may represent Bd vectors. This is the first time P. crucifer from Arkansas has been reported with Bd and increases the number of amphibian species …
Emergent Methodologies: Quantum Qualitative Research, Nicole Weinberg, Gabriel Huddleston, Garrison Daly, Molly Weinburgh
Emergent Methodologies: Quantum Qualitative Research, Nicole Weinberg, Gabriel Huddleston, Garrison Daly, Molly Weinburgh
The Qualitative Report
This methodology paper considers the prospects for quantizing qualitative inquiry in the context of equity and program evaluation. This paper first examines how quantum logics have been applied to the social sciences. Quantum logics refers to a set of generalizations, or rules, that embrace uncertainty and relationality, challenging the linear causality of traditional social science. Then, it reflects upon the impact of the COVID-19 pandemic in the local community as a site to reframe findings and methods through the lens of quantum logic. For example, schools may be understood as quantum systems, co-constituted and rhizomatic communities shaped by entanglement and …
Spatiotemporal Analysis Of Genetic Perturbations Reveals A Genetic Cascade Driving Tribolium Gap Gene Initialization, Mahla Ahmadi, Heike Rudolf, Christine Mau, Jimena Garcia-Guillen, Ezzat El-Sherif
Spatiotemporal Analysis Of Genetic Perturbations Reveals A Genetic Cascade Driving Tribolium Gap Gene Initialization, Mahla Ahmadi, Heike Rudolf, Christine Mau, Jimena Garcia-Guillen, Ezzat El-Sherif
School of Integrative Biological & Chemical Sciences Faculty Publications
The ‘French flag’ model has long served as the prevailing framework for explaining how morphogen gradients generate spatial domains during embryonic development. However, recent evidence indicates that many tissues establish patterns by translating the sequential activation of genes into spatial domains. While the sequential nature of this process is becoming clear, the mechanisms that mediate these temporal dynamics and translate them into stable spatial boundaries remain debated. Using the gap gene network in the flour beetle Tribolium castaneum [which mediates the regionalization of the anterior-posterior (AP) axis into different axial fates through the regulation of downstream Hox genes] as a …
Dietary Flavonoid Intake And Psychological Well-Being – A Bidirectional Relationship, Alysha S. Thompson, Nicola P. Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D. Kubzansky, Claudia Trudel-Fitzgerald, Julia K. Boehm, Eric B. Rimm, Aedín Cassidy
Dietary Flavonoid Intake And Psychological Well-Being – A Bidirectional Relationship, Alysha S. Thompson, Nicola P. Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D. Kubzansky, Claudia Trudel-Fitzgerald, Julia K. Boehm, Eric B. Rimm, Aedín Cassidy
Psychology Faculty Articles and Research
Background and aim
Higher dietary flavonoid intake has been associated with lower risks of mortality and major chronic disease, yet its relationship with psychological well-being (PWB), a key contributor to health and quality of life, remains unclear. This study aimed to investigate bidirectional associations between dietary flavonoid intake and two PWB facets: happiness (positive emotional state) and optimism (generalized expectation of positive outcomes). Specifically, we examined whether (1) overall flavonoid-rich dietary patterns (flavodiet score), (2) intake of specific flavonoid-rich foods, and (3) total flavonoid and subclass intakes were each associated with happiness and optimism over time.Methods
Data were drawn …“Fairy-Tale Beginnings Are Often Pretty Bad.” Filling The Gaps Of The Adoption Experience With Narrative Inquiry, Christina B. Gunther, Michelle A. Cole, Robin L. Danzak
“Fairy-Tale Beginnings Are Often Pretty Bad.” Filling The Gaps Of The Adoption Experience With Narrative Inquiry, Christina B. Gunther, Michelle A. Cole, Robin L. Danzak
The Qualitative Report
This study utilized narrative inquiry to delve into some of the less-celebrated experiences of adoptees and their families. Drawing on focus group data from 17 adult participants with various connections to adoption, we co-constructed three composite narratives centering on darker aspects of the adoption experience: adoptees’ sense of loss, adoption as a secret or taboo, and the challenging implications of interracial adoption. By weaving together participants' authentic voices, the study provides rich insights into the multifaceted experiences of those touched by adoption. The narratives reveal complex emotional journeys of adoptees, including feelings of rejection and grief, identity struggles, and the …
Radionuclide-Stimulated Dynamic Therapy Induces Complementary Immunogenic Necroptosis And Apoptosis Cancer Cell Death Pathways, Christopher Egbulefu, Kvar Black, Xinming Su, Partha Karmakar, Lemoyne Habimana-Griffin, Gail Sudlow, Julie Prior, Ezugo Onejeme, Alex Zheleznyak, Baogang Xu, Yalin Xu, Alison Esser, Matthew Mixdorf, Evan Moss, Brad Manion, Cody Hongsermeier, Nisha Gamadia, Nicole Blasi, Luke Stallings, Chidube Alagbaoso, Nathan Reed, Matthew M Gubin, Chieh-Yu Lin, Robert Schreiber, Katherine Weilbaecher, Samuel Achilefu
Radionuclide-Stimulated Dynamic Therapy Induces Complementary Immunogenic Necroptosis And Apoptosis Cancer Cell Death Pathways, Christopher Egbulefu, Kvar Black, Xinming Su, Partha Karmakar, Lemoyne Habimana-Griffin, Gail Sudlow, Julie Prior, Ezugo Onejeme, Alex Zheleznyak, Baogang Xu, Yalin Xu, Alison Esser, Matthew Mixdorf, Evan Moss, Brad Manion, Cody Hongsermeier, Nisha Gamadia, Nicole Blasi, Luke Stallings, Chidube Alagbaoso, Nathan Reed, Matthew M Gubin, Chieh-Yu Lin, Robert Schreiber, Katherine Weilbaecher, Samuel Achilefu
Faculty, Staff and Student Publications
Radionuclide-stimulated dynamic therapy (RaST) utilizes Cerenkov-radiating radiopharmaceuticals to activate light-sensitive drugs and materials, generating reactive oxygen species (ROS) that inhibit cancer progression. However, the underlying cell death mechanisms are not fully understood. Using ROS-regenerative nanophotosensitizers coated with a tumor-targeting transferrin-titanocene complex and radiolabeled 2-fluorodeoxyglucose, we found that RaST induced apoptosis and necroptosis, characterized by the activation of RIPK-1, RIPK-3, nuclear factor kappa B, and mixed lineage kinase domain-like pseudokinase, leading to membrane permeabilization, cytokine release, and the expression of immunogenic damage-associated molecular patterns. In immune-deficient breast tumor-bearing mice with adequate stroma and growth factors, RaST did not prevent tumor growth …
Comprehensive Metabolic Profiling Across Five Lifespan Stages In Murine Hippocampus And Cortex Reveals Sex-Related Variation In Age-Related Cognitive Decline, Xi Long, Wuping Liu, Changhan Chen, Qi Guo, Yidan Wang, Fang Yu, Yujin Zhang, Rodney E Kellems, Yang Xia
Comprehensive Metabolic Profiling Across Five Lifespan Stages In Murine Hippocampus And Cortex Reveals Sex-Related Variation In Age-Related Cognitive Decline, Xi Long, Wuping Liu, Changhan Chen, Qi Guo, Yidan Wang, Fang Yu, Yujin Zhang, Rodney E Kellems, Yang Xia
Faculty, Staff and Student Publications
This study employs Barnes maze behavioral assessments, untargeted liquid chromatography-mass spectrometry metabolomics, and 13C6-glucose isotopic tracing to systematically investigate cognitive function and metabolic profiles in hippocampal and cortical tissues of male and female mice across five distinct age-ranges. Behavioral analyses reveal significant cognitive decline in both sexes by 16-months-of-age, with females exhibiting more severe impairment by 23-months, demonstrating a sex-related variation. 13C6-glucose tracing analyses reveals that glucose is rapidly and preferentially metabolized toward the Tricarboxylic acid cycle over glycolysis and the pentose phosphate pathway (PPP), with metabolism rates increasing from juvenility to meet developmental demands and maintaining homeostasis into pre-elderly. …
Infant Honey Feeding And Associating Sociodemographic And Clinical Factors: Are There Risks For Infant Botulism In Oman?, Basma Al Yazeedi, Omar Al Omari, Salma Al Yazeedi
Infant Honey Feeding And Associating Sociodemographic And Clinical Factors: Are There Risks For Infant Botulism In Oman?, Basma Al Yazeedi, Omar Al Omari, Salma Al Yazeedi
Sultan Qaboos University Medical Journal
Objectives: This study aimed to assess the risks associated with infant botulism in Oman by examining honey-feeding practices among infants and related sociodemographic and clinical factors. Methods: This cross-sectional study included Omani mothers with children under 5 years and were conveniently recruited from health centres. Mothers completed an infant feeding practices and beliefs survey between October 2023 and March 2024. Data were represented as frequencies and percentages and analysed via Chi-square test and logistic regression. Results: A total of 3,222 participants were included of which 58.8% were aged 26–35 years. The study found that 38.7% of children were fed honey …
Conscious Ai Thought Origination In Llm, Shreyas Kc, Yu Gu
Conscious Ai Thought Origination In Llm, Shreyas Kc, Yu Gu
Defensive Publications Series
The present disclosure relates to the field of Artificial Intelligence (AI), and more specifically to conscious AI systems integrated with Large Language Models (LLMs) for autonomous ideation and decision-making. The present disclosure introduces a consciousness layer to a fine-tuned LLM, enabling the model to continuously generate candidate topics, rank them using a weighted scoring algorithm, and select the highest-priority topic for ideation. The consciousness layer captures and stores intermediate outcomes, embeddings, agent actions, and metadata, which are vectorized and re-injected into the LLM’s context to maintain continuity. This loop operates without external prompting, emulating humans like spontaneous thought and topic …
Implementation Of Sustainable Development Goals Into Technical And Vocational Education And Training Curricula: Regional Differences In Southeast Asia And South Asia, G.L.D. Wickramasinghe, Vathsala Wickramasinghe
Implementation Of Sustainable Development Goals Into Technical And Vocational Education And Training Curricula: Regional Differences In Southeast Asia And South Asia, G.L.D. Wickramasinghe, Vathsala Wickramasinghe
Jurnal Vokasi Indonesia
The implementation of Sustainable Development Goals (SDGs) into curricula is within the current discourse of education for sustainable development to maintain a curriculum relevant to SDGs. We present findings of a research study that investigated the implementation of SDGs into Technical and Vocational Education and Training (TVET) curricula in the Global South - Southeast Asia and South Asia. The objectives of the paper are to present findings on 1) the implementation of nine (9) SDGs into TVET curricula, namely, 1 – ‘No Poverty’, 2 – ‘Zero Hunger’, 3 – ‘Good Health and Well-being’, 10 – ‘Reduced Inequalities’, 11 – ‘Sustainable …
Pengaruh Suplementasi Fitase, Zing Oksida, Dan Cupric Sulfat Terhadap Penampilan Ayam Broiler, Hendi Setiyatwan
Pengaruh Suplementasi Fitase, Zing Oksida, Dan Cupric Sulfat Terhadap Penampilan Ayam Broiler, Hendi Setiyatwan
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan untuk mendapatkan kombinasi fitase, zinc oksid, dan cupric sulfat yang menghasilkan penampilan ayam broiler paling baik. Dua ratus delapan puluh delapan ekor DOC (Unsexed) yang dipelihara selama 42 hari dialokasikan ke dalam rancangan acak lengkap dengan 9 ransum perlakuan dan diulang sebanyak 4 kali. Kombinasi ransum perlakuan terdiri atas R1(ransum kontrol positif); R2 (ransum kontrol negatif); R3 (ransum kontrol negatif + 132,7 ppm ZnO); R4 (ransum kontrol negatif + 286,16 ppm CuSO4); R5 (ransum kontrol negatif + 132,7 ppm ZnO + 286,16 ppm CuSO4 ); R6 (ransum kontrol negatif + fitase 1000 FTU/Kg); R7 …
Perubahan Nilai Nutrisi Ampas Sagu Selam Pada Fase Pertumbuhan Jamur Tiram Putih (Pleurotus Ostreatus) Yang Berbeda, Insun Sangadji, Aminuddin Parakkasi, Komang G. Wiryawan, Budi Haryanto
Perubahan Nilai Nutrisi Ampas Sagu Selam Pada Fase Pertumbuhan Jamur Tiram Putih (Pleurotus Ostreatus) Yang Berbeda, Insun Sangadji, Aminuddin Parakkasi, Komang G. Wiryawan, Budi Haryanto
Jurnal Ilmu Ternak Universitas Padjadjaran
Tujuan penelitian ini untuk mengetahui kandungan nutirisi ampas sagu yang dipermentasi menggunakan Pleurotus ostreatus pada berbegai fase pertumbuhannnya. Rancangan Acak lengkap digunakan pada penelitian ini, perlakuan yang diberikan adalah fase pertumbuhan dari Pleurotus ostreatu. Peubah yang diukur meliputi kandungan protein kasar, bahan kering, ADF, VDF, dan lignin dari ampas sagu yang difermentasi. Hasil penelitian menunjukkkan bahwa terdapat perubahan komposisi nutrisi ampas sago pada berbagai fase pertumbuhan Jamur Pleurotus ostreatus. Kandungan protein meningkat dan kandungan ligninoselulosa menurun, sehingga hasil fermentasi ini sangat potensial untuk dijadikan sebagai pakan ternak ruminansia.
Kata kunci: Ampas sago, Pleurotus ostreatus, pakan ruminansia.
Evaluasi Nilai Nutrisi Tongkol Jagung Hasil Bioproses Kapang Neurospora Sitophila Dengan Suplementasi Sulpur Dan Nitrogen, Nurafni Noverina, Tina Harlina, Dinda Yolandasari, Annisa Septianie
Evaluasi Nilai Nutrisi Tongkol Jagung Hasil Bioproses Kapang Neurospora Sitophila Dengan Suplementasi Sulpur Dan Nitrogen, Nurafni Noverina, Tina Harlina, Dinda Yolandasari, Annisa Septianie
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian bertujuan untuk mengetahui nilai nutrisi tongkol jagung hasil bioproses menggunakan kapang Neurospora sitophila dengan suplementasi sulpur dan nitrogen. Penelitian dilakukan menggunakan metode eksperimen dengan Rancangan Acak Lengkap Pola Faktorial 4 x 4. Faktor pertama adalah taraf suplementasi 0,02 %, 0,04 %, 0,06 % dan 0,08 % sulpur (S), faktor kedua adalah taraf suplementasi 1,00 %, 1,50 %, 2,00 % dan 2,50 % nitrogen (N), tiap perlakuan diulang sebanyak 3 (tiga) kali. Peubah yang diamati untuk melihat respon terhadap perlakuan yang diberikan adalah kandungan protein kasar, protein murni, Non Protein Nitrogen (NPN), lemak kasar, serat kasar, dan Bahan …
Pengaruh Pemberian Ransum Mengandung Minyak Ikan Lemuru Dan Vitamin E Terhadap Kadar Lemak Dan Kolesterol Daging Ayam Broiler, Denny Rusmana, Dulatif Natawiharja, Happali
Pengaruh Pemberian Ransum Mengandung Minyak Ikan Lemuru Dan Vitamin E Terhadap Kadar Lemak Dan Kolesterol Daging Ayam Broiler, Denny Rusmana, Dulatif Natawiharja, Happali
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan untuk mengetahui kadar lemak dan kolesterol daging ayam broiler yang diberi ransum yang mengandung minyak ikan lemuru dan vitamin E serta kombinasinya. Penelitian menggunakan 216 ekor ayam broiler strain CP 707. Rancangan penelitian yang digunakan adalah Rancagan Acak Lengkap dengan pola Faktorial 3x3 yang diulang empat kali dan setiap ulangan terdiri atas 6 ekor ayam. Faktor pertama adalah pemberian Minyak Ikan Lemuru pada tingkat 0%, 3% dan 6%. Faktor yang kedua adalah penambahan suplemen vitamin E pada tingkat 0 ppm, 100 ppm dan 200 ppm. Setiap ransum mempunyai kandungan protein dan energi metabolis yang sama. Untuk mengetahui …
Pengaruh Dedak Padi Dalam Ransum Ayam Lokal Yang Diberi Air Minum Mengandung Cemaran Kadmium Terhadap Performans, Deny Saefulhadjar, Iman Hernaman, Kurnia A. Kamil
Pengaruh Dedak Padi Dalam Ransum Ayam Lokal Yang Diberi Air Minum Mengandung Cemaran Kadmium Terhadap Performans, Deny Saefulhadjar, Iman Hernaman, Kurnia A. Kamil
Jurnal Ilmu Ternak Universitas Padjadjaran
Dedak padi banyak terdapat di daerah perdesaan. Bahan pakan ini mengandung fitat yang tinggi dan dapat mengikat Kadmium (Cd). Penelitian bertujuan untuk mempelajari lokal pengaruh penggunaan dedak padi dalam ransum ayam lokal yang diberi air minum mengandung cemaran kadmium terhadap performans. Dua puluh empat ekor ayam lokal digunakan dalam penelitian ini dengan bobot 422,08 ± 38,78 g. Dedak padi digunakan dalam ransum sebanyak 0, 10, 20, 30, 40, 50% selama 8 minggu. Air minum diberikan ad libitum mengandung 100 mg/kg Cd. Hasil, perlakuan menunjukkan perbedaan yang tidak nyata (P>0,05) terhadap performans. Penggunaan dedak padi sampai 50% lebih menguntungkan. Kadmium …
Pengaruh Suplemen Zn-Proteinat, Cu-Proteinat Dan Kompleks Ca-Minyak Ikan Dalam Ransum Berbasis Pucuk Tebu Amoniasi Terhadap Performans Domba Jantan Persilangan Priangan X Barbados, U. Hidayat Tanuwiria, Budi Ayuningsih
Pengaruh Suplemen Zn-Proteinat, Cu-Proteinat Dan Kompleks Ca-Minyak Ikan Dalam Ransum Berbasis Pucuk Tebu Amoniasi Terhadap Performans Domba Jantan Persilangan Priangan X Barbados, U. Hidayat Tanuwiria, Budi Ayuningsih
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan mempelajari pengaruh suplemen Zn-Proteinat, Cu-Proteinat dan Ca-Minyak dalam ransum berbasis pucuk tebu diamoniasi terhadap pertumbuhan dan efisiensi ransum pada domba jantan persilangan Priangan x Barbados. Percobaan dilakukan terhadap 5 ekor domba jantan yang sedang tumbuh dengan menggunakan rancangan Bujur Sangkar Latin (BSL) 5x5, lima macam ransum yaitu R1 = campuran 50% pucuk tebu amoniasi + 50% konsentrat, R2 = R1 + 2% Zn-proteinat, R3 = R1 + 2% Cu-proteinat, R4 = R2 + 2% Cu-proteinat, dan R5 = R4 + Ca-minyak ikan. Hasil yang diperoleh menunjukkan bahwa pemberian Zn-proteinat, Cu-proteinat dan komplek Ca-minyak tidak mempengaruhi konsumsi ransum, …
A Noncovalent Click-To-Release Strategy To Control Bond Cleavage And Prodrug Activation, Xuancheng Fu, Bowen Xu, Suman Maity, Michelle Wu, Luke G. Westbrook, James H. Henderson, Yaoying Wu, Katie A. Edwards, Atanu Acharya, Xiaoran Hu
A Noncovalent Click-To-Release Strategy To Control Bond Cleavage And Prodrug Activation, Xuancheng Fu, Bowen Xu, Suman Maity, Michelle Wu, Luke G. Westbrook, James H. Henderson, Yaoying Wu, Katie A. Edwards, Atanu Acharya, Xiaoran Hu
Pharmacy Faculty Scholarship
Click-to-release chemistry enables bioorthogonal bond cleavage and controlled release via a click-type ligation reaction serving as both the trigger and means of localization. Extending this concept beyond covalent ligation reactions, we introduce a noncovalent click-to-release strategy based on cucurbit[7]uril-adamantane (CB-Ad) association. The CB host molecule forms a pre-assembled host-guest complex with a self-immolative guest (SIG) SIG1, where the masked SIG remains inert. Introduction of a high-affinity guest Ad initiates the CB-Ad noncovalent click reaction, displacing SIG1 and triggering its self-immolation and cargo release. As a proof-of-concept, we used a prototype prodrug SIG2 to demonstrate our strategy's potential for controlled therapeutic …
The Impact Of Congenital Heart Disease On The Timing Of Alzheimer's Disease In Down Syndrome., Julianne G. Clina, Brian C. Helsel, Sigan L. Hartley, David A. White, Victoria L. Fleming-Batayneh, Benjamin Handen, Bradley Christian, Elizabeth Head, Mark Mapstone, Christy L. Hom, Beau Ances, Jeffrey Burns, H Diana Rosas, Florence Lai, Sharon Krinsky Mchale, Joseph H. Lee, Frederick A. Schmitt, Jordan Harp, Ira T. Lott, Shahid Zaman, Lauren T. Ptomey, Alzheimer Biomarker Consortium–Down Syndrome (Abc‐Ds) Investigators
The Impact Of Congenital Heart Disease On The Timing Of Alzheimer's Disease In Down Syndrome., Julianne G. Clina, Brian C. Helsel, Sigan L. Hartley, David A. White, Victoria L. Fleming-Batayneh, Benjamin Handen, Bradley Christian, Elizabeth Head, Mark Mapstone, Christy L. Hom, Beau Ances, Jeffrey Burns, H Diana Rosas, Florence Lai, Sharon Krinsky Mchale, Joseph H. Lee, Frederick A. Schmitt, Jordan Harp, Ira T. Lott, Shahid Zaman, Lauren T. Ptomey, Alzheimer Biomarker Consortium–Down Syndrome (Abc‐Ds) Investigators
Manuscripts, Articles, Book Chapters and Other Papers
INTRODUCTION: The incidence of Alzheimer's disease (AD) in Down syndrome (DS) exceeds 90%. Approximately 50% of people with DS have congenital heart disease (CHD). Having CHD increases risk for early-onset AD in populations without DS, but it is unclear if CHD influences AD in DS.
METHODS: Data from the Alzheimer Biomarker Consortium-Down Syndrome (ABC-DS) were used. Participants with CHD (n = 82, mean age = 39.9 ± 8.5 years, 97.6% White race) were age- and sex-matched to participants without CHD (n = 82, mean age = 40.5 ± 8.1 years, 98.8% White race). Cognitive assessments and Centiloid load …
Karakteristik Fisik Pakan Itik Bentuk Pellet Yang Diberi Bahan Perekat Berbeda Dan Lama Penyimpanan Yang Berbeda, Jasmal A. Syamsu
Karakteristik Fisik Pakan Itik Bentuk Pellet Yang Diberi Bahan Perekat Berbeda Dan Lama Penyimpanan Yang Berbeda, Jasmal A. Syamsu
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan untuk mengetahui pengaruh penambahan bahan perekat (tepung tapioka dan tepung gaplek) dan lama penyimpanan terhadap sifat fisik pakan itik bentuk pellet yang telah mengalami penyimpanan. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap pola Faktorial 3x3 dengan 4 ulangan. Faktor pertama (A) adalah bahan perekat (ransum pellet tanpa bahan perekat, ransum pellet + tepung tapioka 5%, dan ransum pellet + tepung gaplek 5%) dan faktor kedua (B) adalah lama penyimpanan (0, 2, dan 4 minggu). Data yang diperoleh dianalisis sidik ragam (ANOVA), hasil yang berbeda nyata dilanjutkan dengan uji BNT. Peubah yang diamati adalah berat jenis, kerapatan …
Penggunaan Rumput Laut Dan Sekam Padi Sebagai Sumber Serat Dalam Ransum Terhadap Kadar Lemak Karkas Babi, K. Budaarsa, P.H. Siagian, Kartiarso
Penggunaan Rumput Laut Dan Sekam Padi Sebagai Sumber Serat Dalam Ransum Terhadap Kadar Lemak Karkas Babi, K. Budaarsa, P.H. Siagian, Kartiarso
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian-penelitian yang telah dilakukan menunjukkan adanya suatu hubungan yang sangat kuat antara penyakit jantung dengan tingginya tingkat kolesterol plasma pada manusia dan spesies yang lainnya, termasuk babi. Hal ini sebabkan adanya persamaan anatomi dan fisiologi angara babi dan manusia, informasi terhadap faktor-faktor yang mempengaruhi tingkat lemak tubuh di manusia dapat direfleksikan dengan kondisi yang sama pada babi. Suatu review terhadap beberapa beberapa literatur pada manusia bahwa kandungan serat pada makanan dapat mereduksi lemak tubuh. Babi Landrace lepas sapih sebanyak 35 ekor dengan berat antara 8 – 10 kg telah digunakan untuk menentukan pengaruh pemberian rumput laut dan sekam padi sebagai …
Efek Pengolahan Limbah Sayuran Secara Mekanis Terhadap Nilai Kecernaan Pada Ayam Kampung Super Jj-101, Abun, Denny Rusmana, Deny Saefulhadjar
Efek Pengolahan Limbah Sayuran Secara Mekanis Terhadap Nilai Kecernaan Pada Ayam Kampung Super Jj-101, Abun, Denny Rusmana, Deny Saefulhadjar
Jurnal Ilmu Ternak Universitas Padjadjaran
Limbah sayuran berpotensi sebagai bahan pakan ternak unggas, khususnya ayam kampung super, namun limbah tersebut mudah rusak dan busuk sehingga perlu dilakukan pengolahan. Pengolahan yang dimaksud yaitu dilakukan secara mekanis melalui pengukusan, perebusan, dan penjemuran. Guna menguji kualitas produk pengolahan, dilakukan percobaan pada ayam kampung super JJ-101 melalui pengukuran terhadap nilai kecernaan bahan kering dan protein. Percobaan menggunakan metode eksperimen dengan Rancangan Acak Lengkap (RAL) yang terdiri atas empat perlakuan ransum, yaitu 100 persen ransum kontrol (RB), 85 persen ransum kontrol + 15 persen limbah sayuran hasil pengukusan (RK), 85 persen ransum kontrol + 15 persen …
Penggunaan Daun Lamtoro (Leucaena Leucocephala) Dalam Ransum Terhadap Produksi Pelt Dan Kerontokan Bulu Kelinci, Husmy Yurmiaty, Kusmajadi Suradi
Penggunaan Daun Lamtoro (Leucaena Leucocephala) Dalam Ransum Terhadap Produksi Pelt Dan Kerontokan Bulu Kelinci, Husmy Yurmiaty, Kusmajadi Suradi
Jurnal Ilmu Ternak Universitas Padjadjaran
Lamtoro merupakan tananaman leguminosa yang mengandung gizi lebih baik dibandingkan dengan rumput lapangan, namun penggunaannya perlu dibatasi karena mengandung senyawa mimosin yang dapat memberikan efek negatif pada kulit, khususnya pelt kelinci. Penelitian ini bertujuan untuk mengetahui pada tingkat berapa persen penggunaan lamtoro dalam ransum memberikan pengaruh terhadap produksi pelt dan kerontokkan bulu kelinci peranakan New Zealand White. Penelitian menggunakan 21 ekor kelinci jantan peranakan New Zealand White umur 8 minggu dengan berat pada kisaran 700 – 1100 gram dengan koefisien variasi 8,34%. Rancangan acak lengkap (RAL) digunakan dalam penelitian ini dengan perlakuan tiga macam ransum yang mengandung tepung daun lamtoro …
Pengaruh Pemberian Antanan (Centella Asiatica) Sebagai Penangkal Cekaman Panas Dalam Ransum Broiler Yang Mengandung Hidrolisat Bulu Ayam, Engkus Kusnadi
Pengaruh Pemberian Antanan (Centella Asiatica) Sebagai Penangkal Cekaman Panas Dalam Ransum Broiler Yang Mengandung Hidrolisat Bulu Ayam, Engkus Kusnadi
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian telah dilaksanakan untuk mempelajari pengaruh pemberian antanan (Centella asiatica) sebagai penangkal anti stress dalam ransum ayam broiler yang mengandung hidrolisat bulu ayam. Pada penelitian ini menggunakan 81 ekor broiler umur 10 hari. Terdapat dua macam perlakuan yang diberikan. Perlakuan pertama adalah tiga level kandungan antanan (0, 5, dan 10% kandungan antanan dalam ransum). Perlakuan kedua adalah tiga level tepung bulau (0, 4,8%, dan 9,6% tepung bulu dalam ransum). Hasil penelitian menunjukkan bahwa 5% kandungan antanan dalam ransum cenderung meningkatkan konsumsi pakan dan pertambahan berat badan, dan 4,8% kandungan tepung bulu dalam ransum tidak menurunakn konsumsi pakan dan …
Tingkat Kesukaan Bakso Dari Berbagai Jenis Daging Melalui Beberapa Pendekatan Statistik, Kusmajadi Suradi
Tingkat Kesukaan Bakso Dari Berbagai Jenis Daging Melalui Beberapa Pendekatan Statistik, Kusmajadi Suradi
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan untuk mengetahui tingkat kesukaan baso dari daging yang berbeda melalui beberapa pendekatan statistik. Sebagai perlakuan empat macam bakso yang dibuat dari daging sapi, ayam, kelinci dan domba, masing-masing berjenis kelamin jantan., sedangkan sebagai ulangan digunakan 15 orang panelis agak terlatih. Panelis dikelompokan sebagai ulangan Pada Uji Friedman dan Rancangan Acak Kelompok (RAK), sedangkan pada Uji Kruskal Wallis dan Rancangan Acak Lengkap (RAL), panelis diasumsikan sebagai ulangan yang seragam. Peubah yang diukur adalah tingkat kesukaan terhadap rasa, bau dan kekenyalan dengan skala hedonik sangat suka, suka, agak suka, biasa, dan tidak suka. Hasil penelitian menunjukan, bahwa tingkat kesukaan …
Identifikasi Sifat Kuantitatif Itik Cihateup Sebagai Sumberdaya Genetik Unggas Lokal, Dudi
Identifikasi Sifat Kuantitatif Itik Cihateup Sebagai Sumberdaya Genetik Unggas Lokal, Dudi
Jurnal Ilmu Ternak Universitas Padjadjaran
Penelitian ini bertujuan untuk mengetahui sifat kualitatif dan kuantitatif itik Cihateup sebagai sumberdaya genetik unggas lokal. Metode penelitian yang digunakan adalah survey di sentra peternakan itik Cihateup Kampung Cihateup Kec. Rajapolah, Provinsi Jawa Barat. Pengolahan data menggunakan analisis statistika deskriptif. Hasil penelitian menunjukkan bahwa rataan bobot telur, indeks telur, bobot day old duck (DOD) serta bobot pertama bertelur itik Cihateup berturut-turut adalah 69,34 ± 2,39 g; 81,30 ± 1,19 % (termasuk kategori normal); 45,42 ± 2,40 g; dan 2,7 ± 0,05 kg. Seleksi itik Cihateup ditempat asalnya ini telah dilaksanakan dengan ketat sehingga kemurnian itik tersebut sebagai sumber daya genetik …
Peningkatan Nilai Nutrisi Ampas Sagu (Metroxylon Sp.) Melalui Bio-Fermentasi, Harry Triely Uhi
Peningkatan Nilai Nutrisi Ampas Sagu (Metroxylon Sp.) Melalui Bio-Fermentasi, Harry Triely Uhi
Jurnal Ilmu Ternak Universitas Padjadjaran
Telah dilakukan penelitian bio-fermentasi terhadap ampas sagu yang bertujuan meningkatkan kualitas nutrisi ampas sagu dengan menggunakan probion. Perlakuan yang dugunakan P1 (Ampas sagu Ihur 100 kg + Probion 100 g + Urea 100 g); P2 (Ampas sagu Tuni 100 kg + Probion 100 g + Urea 100 g); P3 ( Ampas sagu Ihur 100 kg + Probion 200 g + Urea 200 g); P4 (Ampas sagu Tuni 100 kg + Probion 200 g + Urea 200 g); P5 (Ampas sagu Ihur 100 kg + Probion 300 g + Urea 300 g); P6 (Ampas sagu Tuni 100 kg + Probion 300 …