Digital Commons Network^™

About The Author: Gerald Callahan

Creative Nonfiction Magazine

No abstract provided.

About The Author: Alison Hawthorne Deming

Creative Nonfiction Magazine

No abstract provided.

Weird Science, Michael G. Stephens

Creative Nonfiction Magazine

No abstract provided.

Science And Poetry: A View From The Divide, Alison Hawthorne Deming

Creative Nonfiction Magazine

No abstract provided.

Introduction: Doctors And Writers, Lee Gutkind

Creative Nonfiction Magazine

No abstract provided.

Rapid Ascent: Rocky Mountain National Park In The Great Acceleration: 1945-Present, Mark Boxwell

Rocky Mountain National Park

A Master's Thesis asserting that wat-time technologies cheap fossil fuels, and a culture of techno-optimism—epitomized by the Mission 66 development program—helped foster a “Great Acceleration” of human alterations of Earth’s natural systems.

Rocky Mountain National Park; Institute of Arctic and Alpine Research; Roaring River; La Poudre Pass; Left-hand Reservoir; Lake Isabelle; Mount. Ida Ridge Pond.

Statement For Management: Rocky Mountain National Pak, James B. Thompson

Rocky Mountain National Park

An inventory of the Rocky Mountain National Park's condition and analysis of its problems for the calendar year of 1992. The report includes photos, charts and maps.

Mills, Enos; Mirror Lake; Harbison Ditch; Grand Ditch; Eureka Ditch; Lee, Jay; Holzwarth Ranch; Housman Ranch; Selak Ditches; Pole Creek; Elk Management; Fire Management; natural Resource management Plan; Maintenance Management System; Bear Lake; Sprague Lake; Wild Basin Ranger Station; Beaver Meadows; Alpine Visitor Center; Longs Peak; Wild Basin; Mill Creek; Bear Lake road; Fall River Road; Utility Area Historic District; Holzwarth Historic District; Timber Creek Campground; Cultural Resource Management Plan; Kawuneech Valley; Lily …

Rocky Mountain National Park's Loch Vale Watershed, Jill Barron

Rocky Mountain National Park

A News Account of the National Park Service investigation whether there is an acidic deposition problem, and how acidic deposition affects high elevation ecosystems of the Southern Rocky Mountains.

Rocky Mountain National Park; Loch Vale Watershed; Acidic Deposition;

Rocky Mountain National Park: How Might Future Warming Alter Visitation, National Park Service Of The United States

Rocky Mountain National Park

An executive report for the calendar year of 2017.

Mills, Enos; Mirror Lake; Harbison Ditch; Grand Ditch; Eureka Ditch: Lee, Jay; Holzwarth Ranch; Housman Ranch; Selak Ditches; Pole Creek; Elk Management; Fire Management; natural Resource management Plan; Maintenance Management System; Bear Lake; Sprague Lake; Wild Basin Ranger Station; Beaver Meadows; Alpine Visitor Center; Longs Peak; Wild Basin; Mill Creek; Bear Lake road; Fall River Road; Utility Area Historic District; Holzwarth Historic District; Timber Creek Campground; Cultural Resource Management Plan; Kawuneech Valley; Lily Lake; Baldpate Estates; Grand Lake Cemetery; Lawn Lake Dam; Cascade Dam; national Parks Service Acts; United States Reclamation …

The Role Of Science Through A Century Of Elk Habitat Management At Rocky Mountain National Park, Therese Johnson

Rocky Mountain National Park

A report on the  role of science through a century of Elk habitat management at Rocky Mountain National Park.

Rocky Mountain National Park; Rocky Mountain National Park Elk; Elk and Vegetation Management Plan;

Review Of Research Conducted In Rocky Mountain National Park And The Tatra National Parks On Poland And Slovakia, William Bowman, Ben Bobwski

Rocky Mountain National Park

Research on Rocky Mountain National Park and the park's interactions with Tatra National Park.

Churchill, Amber; Bowman, William; Institute of Alpine, Anarchic, and Arctic Research; Department of Ecology and Evolutional Biology; University of Colorado Boulder;

Climate Change In Rocky Mountain National Park: Preservation In The Face Of Uncertainty, Jason Vogel, John Gross, Peter Allen, Dave Augeri, Stan Austin, Vaughn Baker

Rocky Mountain National Park

A short report on a Climatology Conference with attention on birds, mammals, hydrology, wetlands, lakes, streams, and fire.

Rocky Mountain National Park; Tatra Mountain Range; Green Valley Lake Colorado Front Range;

The Politics Of Solitude: Listening To Environmental Change In Rocky Mountain National Park, 1945-Present, Mark Boxwell

Rocky Mountain National Park

A telling of the history of mechanical nose's proliferation in RMNP and people's reactions to tourist and their machines.  A sensory and environments history of the park.

Rocky Mountain National Park; Boxwell, Mark; Smith, Mark; Marx, Leo; Sutter, Paul; Coates, Peter; Estes Park; McNeill; Crutzen, Paul ;Nash, Roderick; Brooks Range; Darling, Fraser; Echhorn, Noel; Harvey, Mark; Wilderness Act; Abbey, Edward; Mooney, David; Estes Park Trail Gazette; Estes Park Board of Trustees; Estes Park Airport Committee; Love, John Arthur; Beau; Lucas; Bussey, Woodrow; Federal Aviation Administration; Louter, David; Black, Brian; Eisenhower, Dwight; Drury. Newton; Mission 66;

The History Of Fisheries Management On The West Side Of Rocky Mountain National Park, Christopher M. Kennedy

Rocky Mountain National Park

An Outline of the History of Fisheries Management on the West Side of Rocky Mountain National Park.

Rocky Mountain Fisheries; Rocky Mountain National Park; Grand Lake; Grand Lake Fish Hatchery; Sulphur Springs; Grand County water; Big Thompson River; Forest Canyon.

The Ecological Role Of Elk In Rocky Mountain National Park: Final Report, Ryan Monello, R G. Wright

Rocky Mountain National Park

A report that presents information on the Elk population in Rocky Mountain National Park and Estes Park over the past 70 years.  It includes a summary on the research on the effects of elk on plants and animal populations within the park.

Rocky Mountain National Park; Elk Population; Aspen Ecology; Elk Densities; Elk Movements

Perspectives On Responding To Climate Change In Rocky Mountain National Park, Ben Bobowski, William Monahan, Isabel Ashton

Rocky Mountain National Park

The article highlights climate change issues facing Rocky Mountain NP and follows up with insights into some of the key management challenges and opportunities. It then elaborate on the adaptive management of climate change in Rocky Mountain NP and offers three case studies demonstrating where the park have managed to make significant progress. It concludes with ideas for a way forward, with hopes that they will encourage dialogue on management within Rocky Mountain NP and similar protected areas.

Why Study Climate Change?, Andrew Hansen

Rocky Mountain National Park

The article aims to link science and management to better understand human-caused change in wildland ecosystems within Rocky Mountain National Park and to better inform park management on how to sustain wildland ecosystems in the park.

Final Report To The National Park Service - Colorado State University Cooperative Studies Unit: Vegetational History Of Rock Mountain National Park, Scott Elias, Harvey Nichols

Rocky Mountain National Park

The principal question addressed in this study concerns whether or not the current subalpine ecosystem boundaries are in equilibrium with modern climate, or whether they owe some part of their present distribution to past conditions which no longer exist, and are therefore unusually vulnerable to contemporary damage.

Fusing Fitness And Health Sensor Data From Multiple Sources, Justin Phillips, Daniel Roggen, Robert Harle

Defensive Publications Series

Estimates of cardiorespiratory fitness metrics (e.g., maximal oxygen uptake) from wearable electronic devices are often characterized by significant noise and variability. Inconsistencies arise due to algorithmic differences between manufacturers, sensor inaccuracies, and biological variance. The integration of data from multiple disparate sources lacks a standardized method for weighting measurements based on source reliability or handling late-arriving data. While the disclosed method is described in the context of cardiorespiratory fitness metrics such as VO2 max, it is equally applicable to any changing physiological variable derived from noisy or disparate sources, including but not limited to daily or weekly average blood pressure. …

Skrmetti And The Problem Of Incidental Intent, Martin J. Katz

Sturm College of Law: Faculty Scholarship

The modern Supreme Court has defined “discriminatory intent” as a strict-liability concept. It does not matter why the government sorts people by a protected characteristic, such as race or sex; it matters only that the government does sort people by such a characteristic. This principle is the key holding of affirmative-action cases, such as Students for Fair Admissions, Inc. v. President & Fellows of Harvard College. Yet, in the recent case United States v. Skrmetti, the Court seemed to focus not on the question of whether the government sorted people by sex (it did), but on the question …

National Endowment For The Humanities Awards $38k For ‘Educating The Whole Scientist’, Dave Larsen

College of Arts and Sciences Newsroom

The project's goal is to help science majors become better, well-rounded scientists through integrated science and humanities courses.

Scalable Upstream Design: Case Studies On Scale-Up/-Down Platform Development Enabling Robust And Scalable Raav Production, Huize Yan, Adriluz Sanchez Paternina, Nicholas Deprimo

Advancing Manufacture of Cell and Gene Therapies IX [2026]

Please click Additional Files below to see the full abstract

Pacific Rxtracts - February 2026, Pacific Rxtracts

Pacific RxTracts

Articles:

• Reducing Proteinuria – FDA Accelerates Approval of Sibeprenlimab
• FDA Approves Oral Semaglutide as First GLP-1 Pill for Weight Loss
• New First-Line Digital Treatment for Generalized Anxiety Disorder
• Ammoxetine: A Potential New Antidepressant For Major Depressive
• Extended-Release Buprenorphine Dosing in Individuals With High-Risk Opioid Use
• Managing Acute Agitation Without Injections: Oral Medications in the ED
• Prescription Stimulant Continuation in Pregnancy and Birth Outcomes
• Zoliflodacin - A New Treatment For Gonorrhea
• Intranasal Dexmedetomidine for Postoperative Sleep Quality After Gynecologic Laparoscopy
• FDA Approves Depemokimab, the First Twice-Yearly Biologic for Severe Eosinophilic Asthma Cancer Care
• Engineering Allogeneic CD7-Targeted CAR-T Cells Through Targeted Base …

Residual Jim Crow Ideals And Healthcare For Black Women, Keion Daniels

Father Jack McGrath, S.M., Research Award Presentations

Keion Daniels is a recipient of the 2026 Father Jack McGrath, S.M., Award for Research in Catholic Intellectual Traditions.

Qualitatively Assessing Trade-Offs And Co-Benefits At Local Scales When Considering Carbon Outcomes Among Other Management Goals, Adrienne B. Keller, Ann L. Calhoun, Stephen D. Handler, Maria K. Janowiak, Caitlin E. Littlefield, Brian Miner

Michigan Tech Publications

Natural and working lands are often touted as natural climate solutions due to their ability to take up and store carbon, and land managers are increasingly tasked with considering how management actions impact carbon outcomes alongside other management goals. As a result, there is a need to assess how management actions may drive trade-offs and co-benefits between multiple management goals. However, quantitative analysis of trade-offs is not feasible for many local-scale management projects. We used a case study in an oak savanna in south-eastern Wisconsin, U.S.A. to develop and test a framework for qualitatively analysing local-scale trade-offs. Our framework is …

Characterizing The Effects Of Antimuscarinics On Rhoa Signaling, Zuhra Tukhtamisheva, Elizabeth L. Mcduffie, Jordan Lee, Steven S. An, Reynold A. Panettieri Jr., Charles Scott

Alpha Omega Alpha Research Symposium Posters

Purpose: Airway hyperresponsiveness in asthma is driven by acetylcholine-mediated activation of the muscarinic acetylcholine 3 receptor (M3R), promoting bronchoconstriction, mucus hypersecretion, and airway remodeling. Despite directly targeting this pathway, antimuscarinics remain adjunctive rather than first-line therapy, suggesting a disconnect between biological rationale and clinical efficacy. Recent work from the Scott Lab at Thomas Jefferson University demonstrates that M3R in human airway smooth muscle (HASM) cells drives muscle shortening through G_12/13–driven RhoA signaling rather than through G_q/11-dependent calcium flux. We therefore investigated whether clinically prescribed antimuscarinics effectively inhibit G_12/13-dependent RhoA signaling in HASM cells.

Methods: …

Systematic Evaluation Of Batch Effects In The Cancer Genome Atlas Program Underscores The Need For Batch-Controlled Analysis, Zhongxuan Chen, Stepan Nersisyan, Isidore Rigoutsos, Eric Londin

Alpha Omega Alpha Research Symposium Posters

Purpose: To systematically assess the impact of batch effects on differential expression of isomiR, mRNA, and non-coding RNA (sncRNA) across 13 The Cancer Genome Atlas (TCGA) cancer types and develop a standardized, batch-controlled analysis protocol for TCGA datasets.

Methods: Data analysis and visualization were performed using Python v3.12. Plots were generated using matplotlib and seaborn. isomiR, mRNA, and sncRNA sequences across 13 TCGA cancer types were used. Principal Component Analysis (PCA) was performed using scikit-learn for dimensionality reduction. Differential expression was conducted using DESeq2 under the following protocols: 1) primary tumor samples vs matched normal samples processed in the same …

Elucidating The Binding Site Of The Arrestin-Biased Agonist Icl1-20, Kesara Wein, Roger Armen, Jeffrey L. Benovic, Charles P. Scott

Alpha Omega Alpha Research Symposium Posters

Background and Purpose: 6.7 million Americans live with congestive heart failure (CHF). In CHF, catecholamines are released into cardiac tissue, bind β-adrenergic receptors (βARs), and activate G-protein signaling cascades, causing ischemia and apoptosis. Accordingly, β-blockers are used to antagonize catecholamine binding to βARs and suppress apoptotic downstream effects. However, β-blockers have dose-limiting hypotension, bradycardia and fail to stimulate the cardioprotective β-arrestin signaling pathway. These limits create opportunities for the development of drugs that selectively stimulate β-arrestin signaling while suppressing cardiotoxic G protein signaling. We have previously reported a biased agonist of the β-arrestin pathway (ICL1-20) that selectively stimulates β-arrestin recruitment …

Survival Impact Of Intraoperative Co2 Dysregulation In Patients Undergoing Pancreaticoduodenectomy For Pancreatic Ductal Adenocarcinoma, Ashley Wetzel, Andrea Feci, Joseph Gorman, Isabel Lavine, Edoardo Manca, Richard Zheng, Md, Nader Hanna, Md, Harish Lavu, Md, Charles J. Yeo, Md, Avinoam Nevler, Md

Alpha Omega Alpha Research Symposium Posters

Purpose: Pancreatic ductal adenocarcinomas (PDAC) are aggressive malignancies with poor prognoses. Emerging evidence suggests tissue hypercapnia (elevated CO₂) promotes aggressive, treatment resistant tumor biology. End-tidal CO₂ (ETCO₂) offers a composite measure of ventilation, systemic perfusion, and tissue CO₂ production. During curative-intent pancreaticoduodenectomy, we hypothesized that intraoperative ETCO₂ could serve as a marker of tissue CO₂ dyscapnia; both low levels indicating decreased circulatory reserves and high levels indicating tissue hypercapnia may result in worse outcomes.

Methods: We conducted a retrospective review (2017-2023) of 343 patients undergoing pancreaticoduodenectomy for PDAC. Intraoperative ETCO₂ data …

Boronate Esters For The Binding And Detection Of Low Molecular Weight Volatile Amines, Xiaoning Li, James Boyt, Steven Sloope, Luke T. Lackovic, Mark D. Smith, James J. Lavingne

Faculty Publications

Conjugated thiophene-based diboronate esters, 1–4, were synthesized to investigate how substituents on catechol alter the Lewis acidity and accessibility to boron, and influence binding interactions with low molecular weight Lewis basic amines. Crystallographic analysis indicated that both boron centres bind analyte and that Lewis base coordination induces deplanarization of the conjugated system. Spectroscopic studies demonstrate that amine binding disrupts conjugation, producing distinct and reproducible optical responses that depend on analyte basicity and structure, with association constants in organic solvent ranging from 10³ to 10⁶ M⁻¹. Quantitative binding analyses indicate strong negative cooperativity between the two boron …