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Full-Text Articles in Entire DC Network
Medical-Surgical Nurses’ Perceptions On Incivility In A Hospital Setting, Monsurat Atinuke Mohammed
Medical-Surgical Nurses’ Perceptions On Incivility In A Hospital Setting, Monsurat Atinuke Mohammed
Walden Dissertations and Doctoral Studies
Incivility in nursing has become a chronic issue that harms nurses, patients, teams, and organizations. Individuals often feel belittled, which contributes to frequent job dissatisfaction and resignation, ultimately resulting in financial losses for an organization. The purpose of this qualitative descriptive study, guided by Johnson’s behavioral model, was to explore nurses’ perceptions about incivility in a medical-surgical hospital setting. Ten semistructured audio-recorded interviews were conducted with registered nurses recruited through a professional organization. The data were manually transcribed verbatim and analyzed using Saldana’s approach. Results indicated four themes: (a) workplace culture and interpersonal dynamics, (b) need for support and mentorship, …
Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd
Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd
Faculty Publications
Background: Despite the confirmed beneficial effects on preventing neural tube defects, concerns about high intakes of synthetic folate, or folic acid, in promoting cancer progression have been raised. This study evaluated the association between folate intake and prostate cancer (PCa) aggressiveness among African-American (AA) and European-American (EA) males. Methods: This study included 722 AA and 775 EA men with prostate cancer. Folate intake (dietary folate equivalent (DFE), synthetic folate, natural folate) was estimated using the National Cancer Institute Dietary History Questionnaire and detailed dietary supplement use questionnaire. Analyses included univariable comparisons of demographic and clinical characteristics of the two racial …
Mae Enewsbrief Oct-Dec 2025, Department Of Mechanical And Aerospace Engineering, Michigan Technological University
Mae Enewsbrief Oct-Dec 2025, Department Of Mechanical And Aerospace Engineering, Michigan Technological University
Department of Mechanical and Aerospace Engineering eNewsBrief
No abstract provided.
Spartan Daily, February 26, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, February 26, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, 2026
Volume 166, Issue 16
Turning Zwitterions Into Toughening Agents: Salt-Activated Microdomains In Poly(Vinyl Alcohol) Double-Network Hydrogels, Louis D. Zhang, Jintao Yang, Si Yu Zheng
Turning Zwitterions Into Toughening Agents: Salt-Activated Microdomains In Poly(Vinyl Alcohol) Double-Network Hydrogels, Louis D. Zhang, Jintao Yang, Si Yu Zheng
University Research
Zwitterionic hydrogels, although highly biocompatible, are widely regarded as mechanically fragile, with typical tensile strengths below 0.1 MPa, which restricts their use in load-bearing applications. Here, we address this limitation by integrating a polyzwitterionic network with a poly(vinyl alcohol) (PVA) network through high-speed pregelation agitation that enhances chain entanglement and induces flow orientation. By exploiting the salt-driven conformational transition of zwitterionic chains, a controlled salting-out step generates uniformly dispersed nanoscale microdomains that act as reversible energy-dissipating units. At the same time, balanced hydrogen bonding between the two networks moderates PVA crystallinity, limiting embrittlement while preserving elasticity. The resulting double-network hydrogel …
An Interoperable Vaccine Record: A Roadmap To Realization, Xia Jing, Arild Faxvaag, Christian G Nøhr, David Robinson, Paul G Biondich, Timothy D Law, Hua Min, Adam Wright, Yang Gong, Dean F Sittig
An Interoperable Vaccine Record: A Roadmap To Realization, Xia Jing, Arild Faxvaag, Christian G Nøhr, David Robinson, Paul G Biondich, Timothy D Law, Hua Min, Adam Wright, Yang Gong, Dean F Sittig
Faculty, Staff and Student Publications
Objectives: The objectives of this study were to educate the healthcare professional and the general public about interoperable vaccine records by elaborating on its definition, why we need one, what the challenges are, and what progress has been made in this direction.
Methods: The vaccination practices and vaccine record-keeping in the Nordic countries, the UK, and the USA are used as examples to demonstrate the necessity of interoperable vaccine records. The authors' expertise and experience in interoperability, medicine, and HealthIT, along with the literature, informed this paper's content, structure, and organization. Real-world examples and scenarios illustrate the reality …
From Wrist Data To Lifespan: Elucidating Inflammation-Driven Biological Aging Via Activity Rhythms Captured By Wearable Devices, Jinjoo Shim, Faraz Bishehsari, Mahboobeh Mahdavinia, Jamie M Zeitzer, Elgar Fleisch, Filipe Barata
From Wrist Data To Lifespan: Elucidating Inflammation-Driven Biological Aging Via Activity Rhythms Captured By Wearable Devices, Jinjoo Shim, Faraz Bishehsari, Mahboobeh Mahdavinia, Jamie M Zeitzer, Elgar Fleisch, Filipe Barata
Faculty, Staff and Student Publications
Systemic inflammation ("inflammaging") accelerates biological aging and drives cardiovascular, metabolic, and neurodegenerative disease. Circadian rhythms regulate the amplitude and timing of immune responses, yet their mechanistic role in inflammation and longevity remains unexplored. In 62,000 adults with 7-day wearable accelerometry, interpretable machine learning model identified rhythm amplitude, stability, and moderate-to-vigorous physical activity (MVPA) as dominant predictors of accelerated aging. In a subset of 1521 participants (35% male) with available data on the systemic immune-inflammation index (SII), we further examined the associations between behavioral rhythmicity and inflammation. Low amplitude and poor rhythm stability were associated with 0.31 and 0.18 SD higher …
Pretreatment Risk Model For Radiation-Induced Lymphopenia Is Associated With Adjuvant Durvalumab Efficacy In Patients With Unresectable Stage Iii Nsclc, Peter S N Van Rossum, Pim J J Damen, Francesco Cortiula, Brian P Hobbs, Lorenzo De Marchi, Radhe Mohan, Max Peters, Famke L Schneiders, Dirk De Ruysscher, Robin Wijsman, Joost J C Verhoeff, Ting Xu, Zhongxing Liao, Steven H Lin
Pretreatment Risk Model For Radiation-Induced Lymphopenia Is Associated With Adjuvant Durvalumab Efficacy In Patients With Unresectable Stage Iii Nsclc, Peter S N Van Rossum, Pim J J Damen, Francesco Cortiula, Brian P Hobbs, Lorenzo De Marchi, Radhe Mohan, Max Peters, Famke L Schneiders, Dirk De Ruysscher, Robin Wijsman, Joost J C Verhoeff, Ting Xu, Zhongxing Liao, Steven H Lin
Faculty, Staff and Student Publications
Introduction: Severe radiation-induced lymphopenia (RIL) during concurrent chemoradiotherapy (CCRT) for NSCLC has been associated with poorer outcomes and reduced immunotherapy efficacy. Because RIL often develops late during CCRT, identifying patients at risk before treatment may be clinically relevant. This study aimed to develop and validate a nomogram based on pretreatment predictors for severe RIL, and secondarily to explore associations between predicted RIL risk and adjuvant durvalumab-associated survival.
Methods: A retrospective development cohort of consecutive patients with NSCLC treated with CCRT (2010-2019) was established, along with an independent external validation cohort from other institutions. A multivariable logistic regression model was developed …
An Assessment Of Paediatricians' Knowledge And Perspectives Of Duchenne Muscular Dystrophy In Oman, Zamzam Al Jabri, Maryam Alsawaie, Amal Saki Malehi, Amna Al Futaisi, Fatema Al-Amrani
An Assessment Of Paediatricians' Knowledge And Perspectives Of Duchenne Muscular Dystrophy In Oman, Zamzam Al Jabri, Maryam Alsawaie, Amal Saki Malehi, Amna Al Futaisi, Fatema Al-Amrani
Sultan Qaboos University Medical Journal
Objectives: Duchenne muscular dystrophy (DMD) is a severe, X-linked recessive disorder. The rarity of DMD and insufficient training result in paediatricians being uninformed about the condition, delaying diagnosis and treatment. This study aimed to evaluate the knowledge and perspectives of Oman's paediatric residents and paediatricians regarding the genetics, clinical features and therapy of DMD. Furthermore, this study assessed the association between residency training phases (R1–R4) and post-residency knowledge, together with the influence of professional titles on DMD knowledge. Methods: This prospective cross-sectional study was conducted from October 2024 to February 2025 and included paediatric healthcare practitioners. An online questionnaire was …
Recognizing Structural And Social Determinants Of Health In The Diagnosis And Care Of Dementia, Shana D Stites, Sharnita Midgett, Nisha Patel, Kimberly Halberstadter, Rosalie Schumann, Marissa L Streitz, Yidan Shi, John C Morris, Jason Flatt, Crystal M Glover, Dawn Mechanic-Hamilton
Recognizing Structural And Social Determinants Of Health In The Diagnosis And Care Of Dementia, Shana D Stites, Sharnita Midgett, Nisha Patel, Kimberly Halberstadter, Rosalie Schumann, Marissa L Streitz, Yidan Shi, John C Morris, Jason Flatt, Crystal M Glover, Dawn Mechanic-Hamilton
2020-Current year OA Pubs
Structural and social determinants of health are environmental conditions that affect individuals' health and functioning across the life course. These determinants are salient factors at the apex of individual psychology, community variables, and larger sociological factors, exerting prominent effects on individuals' wellbeing. The National Institute on Aging seeks to understand their influence on aging and Alzheimer's disease. We propose that the benefits of doing so may reach beyond knowledge of disease mechanisms - it may also improve clinical outcomes. We describe efforts introducing structural and social determinants of health data into the national network of Alzheimer's disease research centers. We …
Quaker Campus, February 26, 2026 (Vol. 24, Issue 9), Whittier College
Quaker Campus, February 26, 2026 (Vol. 24, Issue 9), Whittier College
Quaker Campus
No abstract provided.
February 26, 2026, The Daily Mississippian
February 26, 2026, The Daily Mississippian
Daily Mississippian (all digitized issues)
No abstract provided.
Chrysin Alleviates Salt Stress By Enhancing Antioxidant Enzymes, Nutrient Balance, And Phytohormone Contents In Forage Pea, Sedat Severoğlu
Chrysin Alleviates Salt Stress By Enhancing Antioxidant Enzymes, Nutrient Balance, And Phytohormone Contents In Forage Pea, Sedat Severoğlu
Turkish Journal of Agriculture and Forestry
This study aimed to evaluate the potential protective effects of chrysin (Chr), a flavonoid compound, on growth, biochemical,hormonal, and nutrient levels in forage pea (Pisum sativum ssp. arvense L.) seedlings under NaCl-induced salt stress. The experimentwas conducted under controlled greenhouse conditions in a completely randomized design with three different concentrations of Chr(Chr0: 0 mM, Chr1: 0.1 mM, and Chr2: 0.5 mM Chr) and three levels of salt stress (S0: 0 mM, S1: 100 mM, and S2: 200 mM NaCl),resulting in nine treatment combinations (T0: Chr0S0, T1: Chr0S1, T2: Chr0S2, T3: Chr1S0, T4: Chr1S1, T5: Chr1S2, T6: Chr2S0, T7: Chr2S1, andT8: …
Effects Of Gamma Irradiation On Antioxidant Enzyme Activities In Black Carrot Callus Under Drought Stress, Damla Turan Büyükdi̇nç, Di̇lruba Tabay Sümbül, Sheikh Mansoor
Effects Of Gamma Irradiation On Antioxidant Enzyme Activities In Black Carrot Callus Under Drought Stress, Damla Turan Büyükdi̇nç, Di̇lruba Tabay Sümbül, Sheikh Mansoor
Turkish Journal of Agriculture and Forestry
Daucus carota L. (carrot) is a commercially significant root vegetable widely cultivated in temperate regions for its edible taproot and valued for its high nutritional content. This study aimed to investigate the effects of drought stress on callus tissues of the Hatay black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) genotype and to determine the impact of different gamma radiation doses on antioxidant enzyme activities. Black carrot callus tissues were exposed to gamma irradiation at doses of 0, 7, 8, and 9 Gy to evaluate their responses to drought stress. Antioxidant enzyme activities, including superoxide dismutase (SOD), …
Bioactive Profile And Mineral Composition Of Fruit Extracts From Four Wild Hawthorn (Crataegus Spp.) Species, Özlem Çakir, Kübra Çinar Topçu, Abdurrahman Sefali, İshak Bayyi̇ği̇t, Gülçe İlhan, Jyoti̇ Singh
Bioactive Profile And Mineral Composition Of Fruit Extracts From Four Wild Hawthorn (Crataegus Spp.) Species, Özlem Çakir, Kübra Çinar Topçu, Abdurrahman Sefali, İshak Bayyi̇ği̇t, Gülçe İlhan, Jyoti̇ Singh
Turkish Journal of Agriculture and Forestry
This study compared the antioxidant capacity, total phenolic content (TPC), phenolic composition, lipid oxidation level, andmineral profiles of extracts obtained from four wild hawthorn species (Crataegus tanacetifolia, C. orientalis subsp. orientalis, C. orientalissubsp. szovitsii, and C. monogyna) collected from northeastern Türkiye. Significant interspecific variations were observed in DPPH,FRAP, and CUPRAC assays. While C. monogyna had the highest reducing capacity and TPC, C. orientalis subsp. szovitsii had the highestDPPH activity. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis showed that catechin,epicatechin, chlorogenic acid, and quinic acid were the major phenolics, and were particularly abundant in C. monogyna. Despitehaving a …
Production Of The Antitumor Compound Deoxyharringtonine By Suspension-Culturedcells Of Cephalotaxus Hainanensis, Liang Wang, Muhammad Mubashar Zafar, Chongyu Wu, Zhiqiang Xiong, Jingyi Sun, Huapeng Sun, Hanqing Cong, Xuefei Jiang, Mahmoud F. Seleiman, Fei Qiao, Peter Nick
Production Of The Antitumor Compound Deoxyharringtonine By Suspension-Culturedcells Of Cephalotaxus Hainanensis, Liang Wang, Muhammad Mubashar Zafar, Chongyu Wu, Zhiqiang Xiong, Jingyi Sun, Huapeng Sun, Hanqing Cong, Xuefei Jiang, Mahmoud F. Seleiman, Fei Qiao, Peter Nick
Turkish Journal of Agriculture and Forestry
Plant cell fermentation can be a sustainable biotechnological alternative to the wild collection of medicinal plants. As aparadigm, we explored the potential of using the highly endangered endemic tree Cephalotaxus hainanensis, which accumulatescephalotaxine esters—potent anticancer compounds. We successfully established a suspension cell line able to convert cephalotaxineinto its esters, including deoxyharringtonine, harringtonine, isoharringtonine and homoharringtonine at a remarkable maximalconversion rate of up to 86%, when supplemented with L-homoleucine, a precursor for the side chains of these esters. Furthermore, byadding elicitors, we were able to enhance the yield significantly beyond the values expected from the complete conversion of the addedcephalotaxine. In …
Gendered Harms In Armed Conflict: International Legal Responses To The Gendered Effects Of The War In Sudan, Naima Dams
Gendered Harms In Armed Conflict: International Legal Responses To The Gendered Effects Of The War In Sudan, Naima Dams
Theses and Dissertations
This thesis interrogates how international law conceptualizes, prosecutes, and ultimately limits the understanding of sexual violence in contexts of war and displacement. Drawing on feminist legal theory, postcolonial critique, and ethnographic fieldwork with Sudanese women displaced in Egypt, it questions the dominant legal framing of conflict-related sexual violence (CRSV) as episodic, exceptional, and individualized. Instead, it reveals sexual violence as structural, continuous, and embedded in the everyday realities of racialized, gendered, and colonial harm.
Through ethnographical narratives, the study exposes how survivors' experiences often exceed the legibility frameworks of humanitarian and legal institutions, which prioritize spectacular, forensic evidence over slow, …
Merritt-Putnam Symposium | Tumor-Associated Epilepsy And Epilepsy-Associated Tumors: Exploring The Bidirectional Crosstalk Between Tumors And Seizures, Tracy A Bedrosian, Michael Wong, Erin L Heinzen, Benjamin Deneen, Catherine A Christian-Hinman
Merritt-Putnam Symposium | Tumor-Associated Epilepsy And Epilepsy-Associated Tumors: Exploring The Bidirectional Crosstalk Between Tumors And Seizures, Tracy A Bedrosian, Michael Wong, Erin L Heinzen, Benjamin Deneen, Catherine A Christian-Hinman
Faculty, Staff and Students Publications
Links between cancerous and noncancerous brain tumors and epilepsy have long been recognized. However, recent clinical and preclinical studies emphasize that not only do tumors impinge on surrounding brain tissue in ways that promote hyperexcitability and epileptogenesis, but that neural activity also influences tumor progression. In this review, inspired by the Merritt-Putnam Symposium of the 2025 meeting of the American Epilepsy Society, we present a cross-disciplinary dialog between cancer and epilepsy research, including discussion of tumors and epilepsies that are more prominent in pediatric versus adult populations. First, we discuss the neuropathology, genetics, and surgical outcomes of epileptogenic brain tumors, …
Frequency And Self-Reported Outcomes Of Transcranial Magnetic Stimulation For Obsessive Compulsive Disorder In The U.S. And Latin America, Hala Aziz, Guadalupe Vidal-Martinez, Ogechi C Onyeka, Jacey L Anderberg, Javier Vargas-Medrano, Diana Sotelo, Demi Kourtesi, Renee M Frederick, Josselyn S Muñoz, Dayan Berrones, Vanessa Zavala Cruz, Peter Thompson, Silvina Tonarelli, Andrew D Wiese, James J Crowley, Eric A Storch
Frequency And Self-Reported Outcomes Of Transcranial Magnetic Stimulation For Obsessive Compulsive Disorder In The U.S. And Latin America, Hala Aziz, Guadalupe Vidal-Martinez, Ogechi C Onyeka, Jacey L Anderberg, Javier Vargas-Medrano, Diana Sotelo, Demi Kourtesi, Renee M Frederick, Josselyn S Muñoz, Dayan Berrones, Vanessa Zavala Cruz, Peter Thompson, Silvina Tonarelli, Andrew D Wiese, James J Crowley, Eric A Storch
Faculty, Staff and Students Publications
Introduction: Obsessive compulsive disorder (OCD) affects about 1-2% of the global population, with roughly 30% of patients not responding to first-line treatments. Transcranial Magnetic Stimulation (TMS) has some support for treatment-resistant OCD but global use is unclear.
Methods: This study describes the frequency with which TMS was reported to be received among a large cohort of individuals who self-identified as Latino-Hispanic in Latin America and the United States. Among 3,391 participants, 76 (2.2%) had completed TMS for OCD.
Results: Recipients who received TMS exhibited more severe current and lifetime OCD symptoms compared to non-recipients. On average, participants underwent 22.61 TMS …
Coordinated Stimulation Of Axon Regenerative And Neurodegenerative Transcriptional Programs By Atf4 Following Optic Nerve Injury, Preethi Somasundaram, Madeline M Farley, Melissa A Rudy, Katya Sigal, Andoni I Asencor, David G Stefanoff, Malay Shah, Puneetha Goli, Jenny Heo, Shufang Wang, Nicholas M Tran, Trent A Watkins
Coordinated Stimulation Of Axon Regenerative And Neurodegenerative Transcriptional Programs By Atf4 Following Optic Nerve Injury, Preethi Somasundaram, Madeline M Farley, Melissa A Rudy, Katya Sigal, Andoni I Asencor, David G Stefanoff, Malay Shah, Puneetha Goli, Jenny Heo, Shufang Wang, Nicholas M Tran, Trent A Watkins
Faculty, Staff and Students Publications
Stress signaling is important for determining the fates of neurons following axonal insults. Previously, we showed that the stress-responsive kinase PERK contributes to injury-induced neurodegeneration (Larhammar et al., 2017). Here, we show that PERK acts primarily through activating transcription factor-4 (ATF4) to stimulate not only pro-apoptotic but also pro-regenerative responses following optic nerve damage. Using conditional knockout mice, we find an extensive PERK/ATF4-dependent transcriptional response that includes canonical ATF4 target genes and modest contributions by C/EBP Homologous Protein (CHOP). Overlap with c-Jun-dependent transcription suggests interplay with a parallel stress pathway that orchestrates regenerative and apoptotic responses. Accordingly, neuronal knockout of …
Pest Management For Utah Cut Flower Production: Insects And Their Relatives, Nick Volesky, Marion Murray, Melanie Stock
Pest Management For Utah Cut Flower Production: Insects And Their Relatives, Nick Volesky, Marion Murray, Melanie Stock
All Current Publications
Pest management is important in cut flower production, marketability, and farm profitability. This fact sheet focuses on animal pests (insects, arthropods, mollusks, and vertebrates), not diseases or weeds, and has two parts. Part 1 applies Integrated Pest Management (IPM): using preventive techniques, pest thresholds, and best management practices with pests in cut flower crop production. Part 2 highlights the top 10 common pests of cut flowers in Utah and their management.
Gastric Volvulus As A Rare Sequelae Of A Hiatal Hernia: A Case Report And Review Of The Literature, George Ladas, Jake Wiepen, Christopher Stewart, Mitchell Fisher, Suporn Sukpraprut-Braaten, Charles Harper
Gastric Volvulus As A Rare Sequelae Of A Hiatal Hernia: A Case Report And Review Of The Literature, George Ladas, Jake Wiepen, Christopher Stewart, Mitchell Fisher, Suporn Sukpraprut-Braaten, Charles Harper
Student Publications
Gastric volvulus is a rare but potentially life-threatening complication of a hiatal hernia that can result in gastric ischemia or necrosis if not promptly recognized and treated. A 51-year-old man presented with several hours of severe nausea, vomiting, and chest pain. Physical examination was notable for signs of acute distress, and the patient reported dark-colored emesis. Initial laboratory evaluation demonstrated leukocytosis and elevated serum lactate levels. Computed tomography of the chest and abdomen revealed a large hiatal hernia with herniation of the majority of the stomach into the thoracic cavity and findings concerning for mesoaxial gastric volvulus. Esophagogastroduodenoscopy demonstrated ischemic …
Computational Repurposing And Experimental Validation Of Ybx1 Inhibitors In Hepatocellular Carcinoma, Omar Karkoutly, Veerababu Nagati, Subhash Chauhan, Manish Tripathi
Computational Repurposing And Experimental Validation Of Ybx1 Inhibitors In Hepatocellular Carcinoma, Omar Karkoutly, Veerababu Nagati, Subhash Chauhan, Manish Tripathi
School of Medicine Publications
Background/Objectives: Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. While early-stage HCC can often be treated with surgical resection, ablation, or liver transplantation, advanced disease typically relies on systemic chemotherapy. Sorafenib is the standard first-line therapy for advanced and unresectable HCC; however, both intrinsic and acquired resistance remain major clinical challenges. The Y-box binding protein-1 (YBX1), a transcription factor implicated in drug resistance across multiple cancers, is highly expressed in HCC and represents a potential therapeutic target. This study aimed to identify novel YBX1 inhibitors using a drug repurposing strategy to overcome sorafenib resistance. Methods: A …
Hiv Infection, Neurotoxicity, Inflammation, Premature Aging, And Therapeutic Challenges To Plwh: An Overview, Mudit Tyagi, Ulhas P. Naik, Kratika Tyagi, Madhulika Sharma, Gagan Kaushal, Alok Bhushan, Michael Bukrinsky, Priya Tyagi
Hiv Infection, Neurotoxicity, Inflammation, Premature Aging, And Therapeutic Challenges To Plwh: An Overview, Mudit Tyagi, Ulhas P. Naik, Kratika Tyagi, Madhulika Sharma, Gagan Kaushal, Alok Bhushan, Michael Bukrinsky, Priya Tyagi
Department of Medicine Faculty Papers
HIV infection remains a major global health challenge due to its complex pathogenesis and lifelong persistence in people living with HIV (PLWH). A central barrier to eradication is the virus's ability to establish long-lived latent reservoirs in different tissues, including the central nervous system (CNS), where it evades immune clearance and antiretroviral therapy (ART). These reservoirs, seeded early during infection, fuel viral rebound if ART is interrupted, requiring lifelong treatment. In the CNS, HIV persists despite systemic viral suppression because of limited ART penetration across the blood-brain barrier (BBB), and infection of long-lived cells such as microglia and perivascular macrophages. …
Neurosurgical Management Of Pineal Lesions: Insights From A Single-Center Study Of 27 Cases, David Montesinos Contreras, Walter Stummer, Maryam Khaleghi Ghadiri
Neurosurgical Management Of Pineal Lesions: Insights From A Single-Center Study Of 27 Cases, David Montesinos Contreras, Walter Stummer, Maryam Khaleghi Ghadiri
BioMedicine
Introduction: Pineal lesions are rare and surgically challenging due to their deep location, histological diversity, and potential malignancy. The complexity of the pineal region anatomy and the diverse pathological spectrum contribute to the lack of standardized treatment strategies, making appropriate management controversial. Aim: This study aimed to evaluate the surgical outcomes of patients with pineal tumors or cysts and to assess the impact of different surgical approaches, particularly the extent of resection, on progression-free survival. Methods: We conducted a retrospective analysis of 27 patients treated for pineal tumors or cysts at our institution between 2010 and 2020. Data regarding clinical …
A Glimpse Into The Impact Of Physical Activity On Linear Growth In Children And Adolescents Through Activity Restrictions Accompanying The Covid-19 Outbreak, Yi-Chun Lin, Wen-Ling Liao, Chung-Hsing Wang, Fuu-Jen Tsai
A Glimpse Into The Impact Of Physical Activity On Linear Growth In Children And Adolescents Through Activity Restrictions Accompanying The Covid-19 Outbreak, Yi-Chun Lin, Wen-Ling Liao, Chung-Hsing Wang, Fuu-Jen Tsai
BioMedicine
Background: Linear growth in children and adolescents, a key health indicator, is influenced by various factors, including physical activity (PA). The COVID-19 lockdown in Taiwan created a unique opportunity to examine the effect of PA restrictions on growth.
Methods: This retrospective cohort study was conducted at two hospitals in central Taiwan. The study included 72 children and adolescents (26 males, 46 females) who attended a growth clinic. Height and weight measurements were recorded in three stages: pre-lockdown, during lockdown, and post-lockdown. Growth rates were compared across stages using paired t-tests.
Results: The average growth rate was lowest during lockdown (0.0181 …
Assessing The Capabilities Of Ai-Based Large Language Models (Ai-Llms) In Interpreting Histopathological Slides And Scientific Figures: Performance Evaluation Study, Khanisyah Erza Gumilar, Grace Ariani, Priangga A. Wiratama, Rimbun Rimbun, Tri H. Yuliawati, Hong Chen, Ibrahim H. Ibrahim
Assessing The Capabilities Of Ai-Based Large Language Models (Ai-Llms) In Interpreting Histopathological Slides And Scientific Figures: Performance Evaluation Study, Khanisyah Erza Gumilar, Grace Ariani, Priangga A. Wiratama, Rimbun Rimbun, Tri H. Yuliawati, Hong Chen, Ibrahim H. Ibrahim
BioMedicine
Background: Integrating artificial intelligence-based large language models (AI-LLMs) into medical and other scientific domains is increasingly recognized as a tool to support complex tasks, such as interpreting histopathology slides and scientific figures. AI-LLMs can simplify these processes by providing clearer explanations. By improving accessibility and comprehension, AI-LLMs can significantly assist healthcare professionals in diagnosing and therapy determination. Students and the public also find it easier to understand complex scientific concepts and images.
Objectives: This study explores the capability of AI-LLMs in interpreting histopathological slides and scientific images. This study aims to evaluate the performance of AI-LLMs in supporting diagnostics and …
Increased Dairy Product Consumption Is Associated With Shorter Telomere Length In Buccal Cells Among Normotensive Adults, Hsin-Hwa Tsai, Yang-Di Su, Zi-Lun Lai, Chia-Yu Lin, Shu-Fan Lin, Hsiu-Ching Hsu, Wen-Yuan Lin, Po-Ren Hsueh
Increased Dairy Product Consumption Is Associated With Shorter Telomere Length In Buccal Cells Among Normotensive Adults, Hsin-Hwa Tsai, Yang-Di Su, Zi-Lun Lai, Chia-Yu Lin, Shu-Fan Lin, Hsiu-Ching Hsu, Wen-Yuan Lin, Po-Ren Hsueh
BioMedicine
Background: Telomere length (TL) is a biomarker of biological aging and a predictor of age-related diseases. Dietary patterns, including dairy consumption, may influence telomere dynamics, but the evidence remains limited, particularly in Asian populations. This study investigates the association between dairy consumption and relative telomere length (RTL) in Taiwanese adults, with results analyzed by hypertension status.
Methods: A cross-sectional survey was conducted among 259 adults in Taipei, Taiwan. RTL was measured using quantitative PCR from buccal cells. Dietary intake was assessed through self-reported questionnaires, with a focus on dairy frequency and fat content. Multiple linear regression models were used to …
Kriminalistik, Pengungkap Materiele Waardheid, I Nyoman Nurjaya, S.H.
Kriminalistik, Pengungkap Materiele Waardheid, I Nyoman Nurjaya, S.H.
Jurnal Hukum & Pembangunan
Abstract
Hak-Hak Azasi Manusia Menurut Undang-Undang Dasar 1945 Dan Penjabarannya Di Dalam Hukum Perjanjian Nasional, Ny. Mariam Darus Badrulzaman