Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (4196)
- Life Sciences (4188)
- Social and Behavioral Sciences (2200)
- Physical Sciences and Mathematics (2178)
- Medical Sciences (1277)
-
- Education (1252)
- Arts and Humanities (1212)
- Medical Specialties (1135)
- Engineering (951)
- Plant Sciences (896)
- Biology (814)
- Psychology (798)
- Earth Sciences (782)
- Plant Biology (641)
- Agronomy and Crop Sciences (637)
- Agricultural Science (633)
- Law (620)
- Soil Science (610)
- Weed Science (590)
- Plant Pathology (587)
- Public Health (553)
- Environmental Sciences (464)
- Ecology and Evolutionary Biology (450)
- Animal Sciences (407)
- Chemistry (387)
- Higher Education (343)
- Oncology (332)
- Diseases (326)
- Sociology (320)
- Biochemistry, Biophysics, and Structural Biology (318)
- Institution
-
- The Texas Medical Center Library (863)
- University of Kentucky (816)
- University of Texas at Arlington (454)
- Liberty University (410)
- Arkansas State University (317)
-
- Thomas Jefferson University (315)
- Old Dominion University (295)
- TÜBİTAK (286)
- Technical Disclosure Commons (275)
- Walden University (272)
- Universitas Indonesia (250)
- Edith Cowan University (244)
- University of Technology (244)
- University of Montana (241)
- Nova Southeastern University (235)
- University of Arkansas, Fayetteville (230)
- University of Plymouth (227)
- University of Texas Rio Grande Valley (227)
- Utah State University (213)
- University of Al-Qadisiyah (207)
- Washington University School of Medicine (199)
- University of South Carolina (182)
- University of Central Florida (179)
- Universitas Padjadjaran (175)
- Journal of Dental Sciences (170)
- Design Research Society (168)
- City University of New York (CUNY) (163)
- Brigham Young University (155)
- University of Baghdad (155)
- Duquesne University (149)
- Keyword
-
- Humans (841)
- Female (488)
- Male (436)
- Animals (346)
- Mice (225)
-
- Middle Aged (210)
- Adult (183)
- Aged (158)
- ICTS (Institute of Clinical and Translational Sciences) (156)
- Biomarkers (122)
- Artificial intelligence (119)
- Biology (116)
- Child (114)
- Machine learning (111)
- Engineering (101)
- Adolescent (96)
- Climate change (88)
- Mental health (86)
- Inflammation (85)
- Education (84)
- Depression (76)
- Cancer (73)
- Tumor (69)
- United States (69)
- Stress (67)
- Anxiety (66)
- Signal Transduction (65)
- Obesity (64)
- Science (64)
- Young Adult (63)
- Publication
-
- IGC Proceedings (1977-2023) (571)
- Theses and Dissertations (378)
- Faculty, Staff and Students Publications (365)
- Faculty, Staff and Student Publications (360)
- The Shorthorn Newspaper Collection: 1980s (286)
-
- Defensive Publications Series (275)
- All Approved Curriculum (270)
- Doctoral Dissertations and Projects (262)
- Walden Dissertations and Doctoral Studies (251)
- Engineering and Technology Journal (244)
- Research outputs 2022 to 2026 (232)
- Al-Qadisiyah Medical Journal (207)
- Honors Theses (196)
- 2020-Current year OA Pubs (193)
- DRS Biennial Conference Series (156)
- Journal of Dental Sciences (152)
- Baghdad Science Journal (140)
- Undergraduate Student Symposium (139)
- Jurnal Ilmu Ternak Universitas Padjadjaran (137)
- Food and Machinery (136)
- Electronic Theses and Dissertations (132)
- Faculty Publications (128)
- Creative Nonfiction Magazine (126)
- Dissertations (118)
- Theses (109)
- Masters Theses (102)
- Master's Theses (101)
- Manuscripts, Articles, Book Chapters and Other Papers (95)
- All Graduate Theses and Dissertations, Fall 2023 to Present (89)
- Liberty University Research Week (86)
- Publication Type
Articles 12271 - 12300 of 18990
Full-Text Articles in Entire DC Network
Monitoring Soil Degradation In The Mesopotamian Plain Using Gis And Remote Sensing Techniques, Abdulrazak Ziboon, Muthanna Albayati, Fadhaa Dalhel
Monitoring Soil Degradation In The Mesopotamian Plain Using Gis And Remote Sensing Techniques, Abdulrazak Ziboon, Muthanna Albayati, Fadhaa Dalhel
Engineering and Technology Journal
In the present work , various remote sensing techniques have been used to investigate soil degradation in Iraq (The Mesopotamian plain) for the period (1976 - 2021) using different research and data like satellite image such as (Landsat 1-5 MSS 1976 , Landsat 4-5 TM C1 Level-1 1996, Landsat 8 2016 and sentinel-2 2021 ) , using different Program and software (ENVI 5.3 which extract data from image satellite by using TCT , EMI and NDVI indicators , Eras image 2015 use to subset area of interest ,layer stack and merge resolution , Arc GIS 10.7 use to make database …
The Use Of Inexpensive Sorbents To Remove Dyes From Wastewater - A Review, Firas Ahmed, Adnan Abdul Razak, May Muslim
The Use Of Inexpensive Sorbents To Remove Dyes From Wastewater - A Review, Firas Ahmed, Adnan Abdul Razak, May Muslim
Engineering and Technology Journal
Dyes are utilized in various industrial applications, and some businesses' effluents include hazardous dyes. Humans, aquatic creatures, and the environment are all harmed by dyes. As a result, adequately treated dyes that manage wastewater must be before being discharged into nearby bodies of water. Adsorption has proven to be high and cost-effective in removing dyes from wastewater. The sorbent material for dye removal from industrial effluent is activated carbon, but its high cost limits massive-scale utilization. The use of cost-effective adsorbents for wastewater discharge dye elimination is discussed and analyzed in this paper. This review underlines and displays a preview …
Air-Lift Reactor's Characterization Via Computational Fluid Dynamic (Cfd): Review, Marwa Jasim, Thamer Mohammed, Laith Sabri
Air-Lift Reactor's Characterization Via Computational Fluid Dynamic (Cfd): Review, Marwa Jasim, Thamer Mohammed, Laith Sabri
Engineering and Technology Journal
Airlift reactors are seen as the most promising reactor for many valuable productions such as algae culturing. However, this kind of reactor still needs more information and data to understand its phenomena due to limited studies. Also, to reduce the time and offers obtained with sufficient reactor design, capable of achieving high productivities, Computational Fluid Dynamics (CFD) could play an important role in optimizing the reactor design by analyzing the interaction of hydro-dynamics. This review presents the literature review on the recent CFD work for such a reactor that addressed the fluid dynamics parameters, such as bubble dynamics. Earlier researches …
Hydrochemical And Environmental Assessment Of Groundwater In Al-Yusufiyah District South-West Baghdad, Iraq, Rafal Abdulrazzaq, Tariq Hussain, Ghufran Jumaah
Hydrochemical And Environmental Assessment Of Groundwater In Al-Yusufiyah District South-West Baghdad, Iraq, Rafal Abdulrazzaq, Tariq Hussain, Ghufran Jumaah
Engineering and Technology Journal
Groundwater in Yusufiyah represents the main water source for drinking and irrigation purposes in the dry season, so this research was conducted to assess and evaluate the hydrochemistry of groundwater in this area. (15) wells were selected for sampling in this area with depth ranges between 10-20 meters. , Groundwater generally flows from east to west and from northeast to southwest.Physical parameters for water samples were measured included temperature, pH, electrical conductivity (EC), and total dissolved solids (TDS),where the chemical parameters included major cations (Ca+2, Mg+2, Na+2, and K+) and major anions (NO3-1, SO4-2,Cl-, and HCO3-). The results indicated that …
Investigation Of Carboxymethyl Cellulose And Barite Additives On The Corrosion Characteristics Of Water-Based Drilling Mud, Rana Azeez, Najem Alrubaiey, Mohamed Gazi
Investigation Of Carboxymethyl Cellulose And Barite Additives On The Corrosion Characteristics Of Water-Based Drilling Mud, Rana Azeez, Najem Alrubaiey, Mohamed Gazi
Engineering and Technology Journal
Drilling fluids can be considered complex liquids containing several desired materials. These materials (small additives) are specialty products that serve a specific need, such as controlling the rheological properties of the drilling fluid and reducing corrosion for operational drilling of both oil and gas wells. Additives used to resist corrosion are called corrosion inhibitors. Previous research has shown that polymers such as Carboxymethyl Cellulose (CMC) have high characteristics of corrosion inhabitation in an aggressive environment. In this study, the effect of adding two samples of additives, CMC and Barite, on the corrosion of carbon steel in Iraqi bentonite water base …
Physical Properties Of Pure Gold Nanoparticles And Gold Doped Zno Nanoparticles Using Laser Ablation In Liquid For Sensor Applications, Nabaa Hassan, Makram Fakhri, Evan Salim
Physical Properties Of Pure Gold Nanoparticles And Gold Doped Zno Nanoparticles Using Laser Ablation In Liquid For Sensor Applications, Nabaa Hassan, Makram Fakhri, Evan Salim
Engineering and Technology Journal
In this paper, the effect of using laser ablation of pure gold targets to obtain gold Nano rods and for pure zinc targets to obtain zinc oxide nanoparticles was studied separately in ethanol using an Nd:YAG laser tattoo removal (nanosecond pulses) and then mixing the resulting mixtures to obtain gold dopant with zinc oxide. Transmission electron microscopy (TEM), (XRD) X-Ray Diffraction and the optical properties were used to characterize the pure gold Nano rods, ZnO nanoparticles, and Au doped ZnO nanoparticles. Based on XRD and TEM, the results revealed the properties of the produced gold Nano roads. The obtained results …
A Combining Two Ksvm Classifiers Based On True Pixel Values And Discrete Wavelet Transform For Mri-Based Brain Tumor Detection And Classification, Ali Mohammed, Mohammed Noaman, Hassan Azzawi
A Combining Two Ksvm Classifiers Based On True Pixel Values And Discrete Wavelet Transform For Mri-Based Brain Tumor Detection And Classification, Ali Mohammed, Mohammed Noaman, Hassan Azzawi
Engineering and Technology Journal
The studies on brain tumor detection and classification are continuing to improvethe specialists’ ability in diagnosis. Magnetic Resonance Imaging (MRI) is one ofthe most common techniques used to evaluate brain tumors diagnosis. However,brain tumors diagnosis is a difficult process due to congenital malformations andpossible errors in diagnosing benign from malignant tumors. Therefore, thisresearch aims to propose an integrated algorithm to classify brain tumors followingtwo stages using the Kernel Support Vector Machine (KSVM) classifier. Firststage classifies the tumors as normal and abnormal, and the second classifiesabnormal tumors as benign and malignant. The first KSVM employs extractionfeatures by considering the pixel values …
The Proposition Of Three Approaching Ways To Implement Tan-Sigmoid Activation Function In Fpga, Manal Ali, Bassam Abed
The Proposition Of Three Approaching Ways To Implement Tan-Sigmoid Activation Function In Fpga, Manal Ali, Bassam Abed
Engineering and Technology Journal
Hyperbolic tangents and Sigmoid are commonly used for Artificial Neural Networks as activation functions. The complex equation of the activation function is one of the most difficult to be implemented in hardware because containing division and exponential, which gives non-linear behavior. The challenge is building a tan-sigmoid function in hardware with efficient performance. Therefore, this work will focus on implementing the activation function in FPGA. To overcome this challenge, a different approach was proposed in this paper, efficient hardware-implemented for tan-sigmoid in terms of the number of slices occupied and the resources utilization are designed. In this work, three approaches …
Effect Of Temperature And Humidity Factors On Water Production Using Solar Energy With Smart Controlling, Ghusoon Aboud, Hashim Hussein, Ali Numan
Effect Of Temperature And Humidity Factors On Water Production Using Solar Energy With Smart Controlling, Ghusoon Aboud, Hashim Hussein, Ali Numan
Engineering and Technology Journal
The aim of the current work is to study the effect of temperature and humidity factors on the production of water from humid air using clean energy, as we have noticed that both factors have an effective impact on the atmospheric air and on the amount of water that was obtained, which is useful in areas that do not have electric power sources or fresh water, and solar energy is used as the main source of energy in open areas. The motivation is to evaluate the performance of the system in light of different air flow rates and in different …
Blind Assistive System Based On Real Time Object Recognition Using Machine Learning, Mais Kadhim, Bushra Oleiwi
Blind Assistive System Based On Real Time Object Recognition Using Machine Learning, Mais Kadhim, Bushra Oleiwi
Engineering and Technology Journal
Healthy people carry out their daily lives normally, but the visually impaired and the blind face difficulties in practicing their daily activities safely because they are ignorant of the organisms surrounding them. Smart systems come as solutions to help this segment of people in a way that enables them to practice their daily activities safely as possible. Blind assistive system using deep learning based You Only Look Once algorithm (YOLO) and Open CV library for detecting and recognizing objects in images and video streams quickly. This work implemented using python. The results gave a satisfactory performance in detecting and recognizing …
A-Review For The Cooling Techniques Of Pv/T Solar Air Collectors, Wisam Saleh, Abdullateef Jadallah, Ahlam Shuraiji
A-Review For The Cooling Techniques Of Pv/T Solar Air Collectors, Wisam Saleh, Abdullateef Jadallah, Ahlam Shuraiji
Engineering and Technology Journal
A solar thermal collector is one of the most popular applications of solar energy. It is a photovoltaic (PV) cell system with a thermal collector system, this system is utilized in the production of electrical energy and many applications. The system is able to produce electrical energy directly from the sunlight using the photoelectric effect. Meanwhile, it also extracts heat from the PV and heats the fluid (airflow) inside the collector. In this review, the solar PV system and solar thermal collectors are discussed. Usually, solar collectors are exposed to damage and their efficiency decreases when the temperature rises. Need …
Design And Implementation Of Remote Real-Time Monitor System For Prosthetic Limbs, Hussein Mansoure, Hadeel Abdullah
Design And Implementation Of Remote Real-Time Monitor System For Prosthetic Limbs, Hussein Mansoure, Hadeel Abdullah
Engineering and Technology Journal
Persons with Lower-limb amputations experience movement restrictions resulting in worsening their life quality. Wearable sensors are often utilized to evaluate spatial and temporal qualities and kinetic parameters that provide the mechanism to create interactive monitoring of the amputee prosthesis system. Gait events and detection of the gait phase of amputee movement are essential to control the prosthetic devices of lower limbs. This paper presents real-time monitoring to individuals with lower limb amputation by using a medical wireless sensor. However, the proposed system used four medical sensor nodes (such as gait, temperature, the pressure of blood, blood oxygenation (SpO2) )for transmitted …
Corn Oil Performance’S A Bio Cooling Fluid In Electric Distribution Transformer, Ahmed Khudhair, Mohammed Jabal, Samar Ismail
Corn Oil Performance’S A Bio Cooling Fluid In Electric Distribution Transformer, Ahmed Khudhair, Mohammed Jabal, Samar Ismail
Engineering and Technology Journal
Biodegradable (Vegetable) fluids are considered as environmentally friendly fluids and possess an abundant benefit, they are wildly available by means of renewable sources compared to different kinds of mineral-oil. Given the occurrence of environmental pollution and health problems from mineral oils. This paper investigates the effect of utilizing the corn oil for the cooling performing features of distribution electric transformer, and making a comparison with the cooling performance of the electric transformer whith cooling by the commercial mineral fluid. This investigation is done by using the four- ball machine and electric transformers. Each experiment that was executed complies with ASTM …
Thermal Performance Of An Evacuated-Tube Solar Collector Using Nanofluids And An Electrical Curtain Controlled By An Artificial Intelligence Technique, Hussam Rashid, Khalid Sultan, Hosham Anead
Thermal Performance Of An Evacuated-Tube Solar Collector Using Nanofluids And An Electrical Curtain Controlled By An Artificial Intelligence Technique, Hussam Rashid, Khalid Sultan, Hosham Anead
Engineering and Technology Journal
This paper studies the improvement of an evacuated tube solar collectors(ETSCs) performance in two way. The first is by adding a finned electronic curtain in front of the solar collector. While the second is by using a nanofluid instead of pure water. The purpose of the curtain is to increase the amount of solar radiation reflected toward the collector. The curtain is distinguished by its self-ability to track the sun's rays automatically. The electronic curtain is also closed to shade the tubes depending on the movement of the electronic curtain's fins and the nanofluid's temperatures. MATLAB algorithm has been used …
Process To Produce Pyridines And Alkyl Pyridines, Maruthi Sreekanth Pavani, Udayshankar Singh
Process To Produce Pyridines And Alkyl Pyridines, Maruthi Sreekanth Pavani, Udayshankar Singh
Defensive Publications Series
A process for increasing the overall yield of pyridine or its alkyl pyridine derivatives during a base synthesis reaction is disclosed. The process comprises reacting a C2 to C5 aldehyde, a C3 to C5 ketone or a combination thereof, with ammonia and, optionally, formaldehyde, in the gas phase and in the presence of an effective amount of a particulate catalyst comprising a ZSM-5 zeolite stabilized with either alumina-phosphate, ceria-alumina phosphate, or iron oxide-alumina phosphate, or a combination thereof, a binder, and clay, wherein the zeolite has a silica to alumina ratio (SAR) of 22 to 50. A process for enhancing …
Gci #121 V5.0: Closed‑Loop Regenerative Revascularization System Integrating Acoustic Vortex Dynamics, Real‑Time Imr Feedback, And Mitochondrial Payload Synchronization, Michael Victor Caldwell Mr.
Gci #121 V5.0: Closed‑Loop Regenerative Revascularization System Integrating Acoustic Vortex Dynamics, Real‑Time Imr Feedback, And Mitochondrial Payload Synchronization, Michael Victor Caldwell Mr.
Defensive Publications Series
This disclosure describes GCI #121 v5.0, a multi‑modal engineering system for intravascular obstruction removal and regenerative payload delivery. The system integrates several previously unreleased GCI inventions into a unified closed‑loop architecture called Closed‑Loop Regenerative Revascularization (CLRR). The design combines: (1) Acoustic vortex thrombolysis using a laminar‑helical manifold (GCI #118) and a multi‑element ultrasound array (GCI #75) to generate controlled vortex flow and acoustic energy without mechanical rotation; (2) Real‑time microvascular sensing using a fiber‑optic IMR feedback loop (GCI #14) enhanced by a quantum‑tunneling bio‑impedance switch (GCI #122) to maintain sensing accuracy during debris load; and (3) Synchronized biological …
20th Annual Research In The Capitol [Program], March 9, 2026, University Of Northern Iowa. University Honors Program. Iowa State University. Honors Program. University Of Iowa. Honors Program.
20th Annual Research In The Capitol [Program], March 9, 2026, University Of Northern Iowa. University Honors Program. Iowa State University. Honors Program. University Of Iowa. Honors Program.
Research in the Capitol Programs
Program of research presentations given at the Capitol by students from the University of Northern Iowa, Iowa State University, and the University of Iowa.
Cv: Carly Jones (Physical Therapy), Carly Jones
Cv: Carly Jones (Physical Therapy), Carly Jones
Rehabilitation Sciences Department Curricula Vitae
No abstract provided.
Cv: Michelle Walaszek (Physical Therapy), Michelle Walaszek
Cv: Michelle Walaszek (Physical Therapy), Michelle Walaszek
Rehabilitation Sciences Department Curricula Vitae
No abstract provided.
Horizontal Gene Transfer In Neisseria, Wen Ting Dong
Horizontal Gene Transfer In Neisseria, Wen Ting Dong
Theses
Antibiotics are a special category of drugs that help treat bacterial infections by killing bacteria or hindering their growth and replication. Antibiotics are greatly significant in modern medical practices, providing an effective treatment for bacterial infections as well as enabling organ transplants, open surgeries, and chemotherapy to be possible. Unfortunately, cases of antibiotic resistance were observed shortly after the introduction of antibiotics. The appearance and spread of these resistant strains poses a significant threat to public health safety. The Centers for Disease Control (CDC) estimates there are 2,868,700 antibiotic-resistant bacterial and fungal infection cases per year in the United States, …
Cv: John Halloran, John Halloran
Cv: John Halloran, John Halloran
Social Work Department Faculty Curricula Vitae
No abstract provided.
Crow's Nest, March 9, 2026, Crow's Nest Staff
Crow's Nest, March 9, 2026, Crow's Nest Staff
Crow's Nest
The March 9, 2026 issue of Crow's Nest.
Real-World Precision Medicine Data In Metastatic Prostate Cancer - A Retrospective Cohort Study, Awais Paracha, Derek Tran, Margot Noyelle, Jonathan Kapilian, Zohair Siddiqui, Adrian Choppa, Anthony Corsi, Jacob Stone, Xin-Hua Zhu
Real-World Precision Medicine Data In Metastatic Prostate Cancer - A Retrospective Cohort Study, Awais Paracha, Derek Tran, Margot Noyelle, Jonathan Kapilian, Zohair Siddiqui, Adrian Choppa, Anthony Corsi, Jacob Stone, Xin-Hua Zhu
Department of Medicine Faculty Papers
Background: Prostate cancer (PC) is the most common cancer in men in the United States with a 5-year relative survival rate for people with distant metastases of 36%. We conducted a single institution, retrospective cohort study of patients with metastatic PC to investigate whether certain gene mutations can be used as predictive biomarkers.
Methods: 200 patients with metastatic hormone sensitive (mHSPC) and castration resistant (mCRPC) prostate cancer who had a FoundationOne report and were treated from June 2007 to October 2024 were included in the study. Disease progression was evaluated according to RECIST criteria, PCWG3 criteria, and PSA values. Assessed …
The Echo: March 9, 2026, Taylor University
The Echo: March 9, 2026, Taylor University
2025-2026 (Volume 113)
No abstract provided.
The Comparison Of Fresh And Dry Duckweed (Lemna Minor L.) On Metal (Cr6+, Cd2+, And Zn2+) Removal From Wastewater, Rahin Islam, Noah Smith, Ben Jang, Lin Guo
The Comparison Of Fresh And Dry Duckweed (Lemna Minor L.) On Metal (Cr6+, Cd2+, And Zn2+) Removal From Wastewater, Rahin Islam, Noah Smith, Ben Jang, Lin Guo
Student Publications
Heavy metals contaminating the environment is a global concern. Duckweed (Lemna minor) is a promising plant for the phytoremediation and biosorption of metal-contaminated water. Although studies have shown that duckweed can remove multiple metals, there is limited research comparing the efficiency of fresh and dried biomass for wastewater treatment. To evaluate the performance of both forms, fresh and dried duckweed were exposed to metal solutions containing varying concentrations of Cr6+, Cd2+, and Zn2+ (5 mg/LCr6+ +1mg/LCd2+ 10mg/LZn2+;10mg/LCr6+ +5mg/LCd2+ +50mg/LZn2+; or 50 mg/LCr6+ +25mg/LCd2+ +250mg/LZn2+)for a duration of 168 h. Metal uptake in fresh duckweed followed zero-order kinetics for Cr6+, Cd2+, …
Quantifying Location-Based Variability Of Regional Brain Metabolism Using Microsamples From Apoe Knock-In Mice, Jason G. Wells, Esteban G. Colman, John C. Price
Quantifying Location-Based Variability Of Regional Brain Metabolism Using Microsamples From Apoe Knock-In Mice, Jason G. Wells, Esteban G. Colman, John C. Price
Undergraduate Honors Theses
Apolipoprotein E (ApoE) is an important lipid transporter in the brain. There are three different ApoE variants: ApoE2, ApoE3, and ApoE4. Each of these variants either contribute to or protect against Alzheimer’s disease (AD). The Hippocampus (HC) and the Entorhinal Region (ER) of the brain consistently develop AD pathology first. We hypothesize that ApoE variants affect lipid and protein metabolism in these regions more strongly than in others. Differences in the regional regulation and the ApoE-isoform impacts of these metabolic pathways remain unknown.
We measured brain protein turnover rates in ApoE knock-in mice labeled with deuterated water. Using a laser …
The Rider (2026-03-09), Daniela Chapa-Reyes
Dual Phagocytosis-Checkpoint Blockade Revitalizes Immune Surveillance In Mouse Models Of Glioblastoma, Jonghoon Ha, Yifan Wang, Yifan Ma, Annette Wu, Shiyan Dong, Seong Dong Jeong, Jared L Edwards, Mengyu Chang, Yen-Tzu Chang, Xiaotian Wang, Maurice Dufilho, Michelle Najarro Torres, Shannon Mccabe, Weiye Deng, Adam J Grippin, Jeffrey S Weinberg, Shaan M Raza, Franco Demonte, Ian E Mccutcheon, Sujit Prabhu, Sherise D Ferguson, Chibawanye I Ene, Kadir Akdemir, Sreyashi Basu, Sonali Jindal, Benjamin R Schrank, Jian Hu, Sangeeta Goswami, Vinay K Puduvalli, Frederick F Lang, Kristin Huntoon, Padmanee Sharma, Betty Y S Kim, Wen Jiang
Dual Phagocytosis-Checkpoint Blockade Revitalizes Immune Surveillance In Mouse Models Of Glioblastoma, Jonghoon Ha, Yifan Wang, Yifan Ma, Annette Wu, Shiyan Dong, Seong Dong Jeong, Jared L Edwards, Mengyu Chang, Yen-Tzu Chang, Xiaotian Wang, Maurice Dufilho, Michelle Najarro Torres, Shannon Mccabe, Weiye Deng, Adam J Grippin, Jeffrey S Weinberg, Shaan M Raza, Franco Demonte, Ian E Mccutcheon, Sujit Prabhu, Sherise D Ferguson, Chibawanye I Ene, Kadir Akdemir, Sreyashi Basu, Sonali Jindal, Benjamin R Schrank, Jian Hu, Sangeeta Goswami, Vinay K Puduvalli, Frederick F Lang, Kristin Huntoon, Padmanee Sharma, Betty Y S Kim, Wen Jiang
Faculty, Staff and Student Publications
Macrophage-mediated phagocytosis of tumor cells elicits potent antitumor immunity. Nonetheless, sole-blockade of the anti-phagocytosis molecule CD47 has yielded insufficient therapeutic outcomes. Here, we report that glioblastoma (GBM) cells expressed abundant levels of phagocytosis checkpoint CD24. We further show that dual blockade of CD24 and CD47 synergistically enhances the pro-phagocytic activity of macrophages, thereby improving tumor antigen cross-presentation and activating the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway. This innate immune activation facilitates T cell infiltration into tumors and sensitizes tumors to anti-PD1 therapy, improving survival outcomes in murine GBM models, including immunosuppressive tumors reflecting human GBM-like features. Thus, our …
Radiv2: An Adaptable And Versatile Diagenetic Model For Coastal And Open-Ocean Sediments, Hinne F. Van Der Zant, Olivier Sulpis, Jack J. Middelburg, Matthew P. Humphreys, Raphaël Savelli, Dustin Carroll, Dimitris Menemenlis, Kay Sušelj, Vincent Le Fouest
Radiv2: An Adaptable And Versatile Diagenetic Model For Coastal And Open-Ocean Sediments, Hinne F. Van Der Zant, Olivier Sulpis, Jack J. Middelburg, Matthew P. Humphreys, Raphaël Savelli, Dustin Carroll, Dimitris Menemenlis, Kay Sušelj, Vincent Le Fouest
Faculty Research, Scholarly, and Creative Activity
Ocean biogeochemistry is being altered by anthropogenic processes such as warming, acidification, eutrophication, and deoxygenation. Global-ocean biogeochemistry models are essential for investigating present and projecting future conditions, yet they often lack detailed representations of seafloor processes, despite the seafloor’s important role in material exchange between the biosphere and geosphere. To improve the representation of exchange across the sediment-water interface, we present RADIv2, a flexible and computationally efficient diagenetic model designed to simulate benthic biogeochemical processes across a range of marine environments, from coastal zones to abyssal plains. RADIv2 incorporates key features such as benthic methane cycling, a hydrodynamically controlled diffusive …
Measuring What Matters: Specifications Grading And Latin* Students’ Mathematics Identity, Luis Miguel Fernández, Mayra Ortiz Galarza, Cristina Villalobos, Martha Asare
Measuring What Matters: Specifications Grading And Latin* Students’ Mathematics Identity, Luis Miguel Fernández, Mayra Ortiz Galarza, Cristina Villalobos, Martha Asare
School of Mathematical & Statistical Sciences Faculty Publications
This study examined Specifications Grading, an alternative grading system emphasizing clearly defined learning outcomes and revision, and mathematics identity among 846 Latin* Calculus I students at a Hispanic-Serving Institution. Mathematics identity, comprising competence/performance, recognition, and interest, was measured at the beginning and end of the semester. Repeated-measures analyses indicated stable competence/performance and recognition alongside declines in interest. Specifications Grading was associated with increased mathematics identity, and multilingual students experienced smaller declines than their peers overall.
-
Este estudio examinó la calificación por especificaciones, un sistema de evaluación alternativo que enfatiza resultados de aprendizaje claramente definidos y oportunidades estructuradas de revisión, …