Digital Commons Network^™

The Reliability, Validity, And Sensitivity Of Physical Working Capacity At The Pain Intensity Threshold, Danielle A. Sterner

Graduate Studies Theses and Dissertations 2026

The purpose of this dissertation was to evaluate the reliability, validity, and responsiveness to training intervention of a pain-anchored capacity threshold, the Physical Working Capacity at the Pain Intensity Threshold (PWC_PIT), as a practical submaximal marker of endurance-related exercise tolerance. Study one examined the test-retest reliability of pain-based, perceptual, and physiological physical working capacity measures in recreationally active men using a standardized multi-bout cycling protocol, with pain intensity responses demonstrating strong reproducibility and low measurement error, supporting the stability of pain-anchored thresholds when standardized procedures are applied. Study two evaluated the validity of PWC_PIT by examining pain …

Improving Compliance With Safe Sleep Guidelines For Vulnerable Patients In A Community Safety Net Hospital Neonatal Intensive Care Unit, Thomas Lu, Kelsi Morgan, Ashlee Smith-Patel, Kelli Phillips, Joseph Hagan, Pablo Lohmann, Caraciolo Fernandes, Lisa Owens, Daniela Dinu

Faculty, Staff and Students Publications

Introduction: Modeling safe sleep in the neonatal intensive care unit (NICU) increases the likelihood that parents will follow these practices after discharge. Many NICU infants are put to sleep unsafely, and unsafe sleep practices are the leading cause of nonnatural death among children locally. We created safe sleep standards for infants older than 32 weeks based on national guidelines: infants should be placed supine in a flat, empty crib and should never be swaddled loosely. We aimed to increase the weekly percentage compliance with safe sleep recommendations from a baseline of 58% (0.58 compliant) to 85% (0.85 compliant) by March …

Injuries In Children Undergoing Subspecialty Abuse Evaluations Because Of Intimate Partner Violence, Jan Leonard, Kristine A Campbell, Daniel M Lindberg, Angela N Bachim, Farah W Brink, Lori D Frasier, Nancy S Harper, Claire Hickey, Natalie Laub, John D Melville, Hannah Sahud, Philip V Scribano

Faculty, Staff and Students Publications

Background and objectives: Intimate partner violence (IPV) and child physical abuse often co-occur, but the frequency and risk factors for abusive injuries in IPV-exposed children remain unknown. Our objectives were to (1) determine frequency of skeletal surveys (SSs) and neuroimaging use because of IPV and their diagnostic value in children aged less than 24 months evaluated by a child abuse pediatrics specialist (CAP) and (2) identify factors associated with performance of and findings on SS and neuroimaging.

Methods: We conducted a retrospective study of children aged less than 24 months undergoing CAP consultations because of IPV exposure from February 2021 …

Association Of Alcohol Use With Helmet Use In Cyclists: Analysis Of The National Trauma Data Bank, Emanuel Narcis Husu

Faculty, Staff and Students Publications

Background: Helmet use significantly reduces the risk of traumatic brain injury among cyclists; however, the influence of alcohol use on helmet-wearing adherence remains understudied in large national data sets. The goal of this study was to investigate the relationship between alcohol use and helmet use in injured cyclists.

Methods: This study is a retrospective cross-sectional analysis of 155 766 cyclists with traumatic injuries from the National Trauma Data Bank spanning 8 years (2017-2023). Cyclists were categorized by blood alcohol concentration (BAC) as follows: not screened, sober (BAC < 0.02), impaired (BAC 0.02-0.08), intoxicated (BAC ≥0.08), and multidrug intoxicated (BAC ≥0.08 plus ≥1 positive drug screen). The primary outcome was helmet usage. Secondary outcomes included mortality, hospital and intensive care unit length of stay, Injury Severity Score, and adverse events. Comorbid substance use disorders were considered as covariates.

Results: Alcohol use was associated with a dose-response decrease in helmet use. Helmet …

Beyond Drugs And Surgery: Superselective Adrenal Artery Embolization Redefines Primary Aldosteronism Management-A Systematic Review And Meta-Analysis, Mohammad Mirza-Aghazadeh-Attari, Mohammad Ghasemi Rad, Afshin Mohammadi

Faculty, Staff and Students Publications

Background: Primary aldosteronism (PA) is a leading cause of secondary hypertension associated with increased cardiovascular and cerebrovascular risk. Superselective adrenal artery embolization (SAAE) has emerged as a minimally invasive alternative to adrenalectomy and mineralocorticoid receptor antagonists (MRAs). This systematic review and meta-analysis evaluates the efficacy and safety of SAAE in PA management.

Methods: We searched PubMed, Web of Science, Embase, and Cochrane Library through June 2026 for studies enrolling patients with PA treated by SAAE. Outcomes of interest were changes in blood pressure (BP), biochemical markers (serum potassium, aldosterone, renin activity, and aldosterone-to-renin ratio), clinical and biochemical response rates, daily …

Chemoradiation After Chemotherapy For Metastatic Cervical Cancer Can Provide Chemo-Free Time, Madeline Flanagan, Shelly Sharma, Tracilyn Hall, Anthony Costales, Jan Sunde, Claire Hoppenot

Faculty, Staff and Students Publications

Introduction: Stage IVB cervical cancer is treated with a life-prolonging and palliative intent with systemic chemotherapy and immunotherapy. The purpose of this study was to evaluate the number of these patients who had an adequate response to chemotherapy to be eligible for consolidative radiosensitizing chemotherapy and radiation (chemoradiation) and subsequent outcomes.

Materials and methods: This is a retrospective review of metastatic cervical cancer patients treated with chemotherapy and evaluated for treatment with consolidative pelvic chemoradiation at a single safety-net hospital system from 2016 to 2024. Demographic data and clinical information were collected from electronic medical records. Stata was used for …

Interdisciplinary Swiss Consensus Recommendations For Follow-Up After Radical Cystectomy And Trimodal Treatment For Muscle-Invasive Bladder Cancer, Nicolas Arnold, Winfried Arnold, Fabian Aschwanden, Panagiotis Balermpas, Jörg Beyer, Uwe Bieri, Joost Boormanns, Richard Cathomas, Berardino De Bari, Marco Dressler, Daniel S Engeler, Andreas Erdmann, Andrea Gallina, Silvia Gomez, Matthias Guckenberger, Thomas Herrmann, Thomas Hermanns, Ilaria Lucca, Hubert John, Thomas Matthias Kessler, Jan Klein, Mohamed Laouiti, David Lauffer, Seth Paul Lerner, Agostino Mattei, Michael Müntener, Daniel Nguyen, Philipp Niederberger, Alexandros Papachristofilou, Lukas Prause, Paul Martin Putora, Karsten Reinhardt, Emanuela Salati, Philippe Sèbe, Mohamed Shelan, Silvan Sigg, Räto Thomas Strebel, Arnoud Jan Templeton, Ursula Vogl, Marian Severin Wettstein, Stephen Wyler, Deborah Zihler, Thomas Zilli, Daniel Zwahlen, Beat Roth, Christian Daniel Fankhauser

Faculty, Staff and Students Publications

Introduction: Radical cystectomy or trimodal therapy are treatment options for non-metastatic bladder cancer. However, there is limited evidence guiding post-treatment follow-up regimens, resulting in variations in care.

Objective: A Swiss consensus meeting aimed to identify gaps in follow-up strategies and subsequently tailoring follow-up protocols after curative treatment for bladder cancer.

Methods: A consensus meeting including participants from urology, oncology, radiation oncology, neuro-urology, international advisors, and patient representatives was held. 19 pre-formulated questions addressing follow-up duration, frequency, and modalities after radical cystectomy or trimodal therapy for bladder cancer were discussed and voted by participants.

Results: 42 experts from 22 institutions participated …

Probing Hard/Soft Factorization Via Beam-Spin Asymmetry In Exclusive Pion Electroproduction From The Proton, A. C. Postuma, G. M. Huber, D. J. Gaskell, N. Heinrich, T. Horn, M. Junaid, S. J. D. Kay, V. Kumar, P. Markowitz, J. Roche, R. Trotta, A. Usman, B. -G Yu, T. K. Choi, K. -J. Hong, S. Ali, R. Ambrose, D. Androic, W. Armstrong, A. Bandari, V. Berdnikov, H. Bhatt, D. Bhetuwal, D. Biswas, M. Boer, P. Bosted, E. Brash, A. Camsonne, J. -P. Chen, J. Chen, M. Chen, M. E. Christy, S. Covrig, M. M. Dalton, W. Deconinck, M. Diefenthaler, B. Duran, D. Dutta, M. Elaasar, R. Ent, H. Fenker, E. Fuchey, D. Hamilton, J. -O Hansen, F. Hauenstein, S. Jia, M. K. Jones, S. Joosten, M. L. Kabir, A. Karki, C. Keppel, E. Kinney, N. Lashley-Colthirst, W. B. Li, D. Mack, S. Malace, M. Mccaughan, Z. E. Meziani, R. Michaels, R. Montgomery, M. Muhoza, C. Muñoz Camacho, G. Niculescu, Z. Papandreou, S. Park, E. Pooser, M. Rehfuss, B. Sawatzky, G. R. Smith, H. Szumila-Vance, A. Teymurazyan, H. Voskanyan, B. Wojtsekhowski, S. A. Wood, Z. Ye, C. Yero, J. Zhang, X. Zheng

Physics Faculty Publications

Deep exclusive meson production (DEMP) reactions, such as p(e⃗ , e'π⁺)n, provide opportunities to study the three-dimensional structure of the nucleon through differential cross section and beam-and target spin asymmetry measurements. This work aims to probe the onset of the hard/soft factorization regime through the exclusive p (e⃗, e'π⁺)n reaction, as measured in the KaonLT experiment at Jefferson Lab Hall C. A 10.6 GeV Longitudinally polarized electron beam was incident on an unpolarized liquid hydrogen target, and the scattered electron and produced meson were detected in two magnetic focusing spectrometers, enabling precision cross section measurements. The cross section ratio σ …

The All Of Us Evenings With Genetics Research Program, Julie Coleman, Laterrica Williams, April Adams, Ashley Butler, Elizabeth Atkinson, Shamika Ketkar, Steven Scherer, Kim Worley, Susan Fernbach, Keasia Daniels, Latanya Hammonds-Odie, Laura Rosales, Brendan Lee, Debra Murray

Faculty, Staff and Students Publications

The All of Us Evenings with Genetics (All of Us EwG) Research Program, funded in part by the National Institute of Health’s All of Us Research Program, engages researchers to utilize the All of Us Researcher Workbench to advance precision medicine. The All of Us EwG program has two core aims: (1) address barriers to research productivity for minorities, disadvantaged, and persons with disabilities aspiring to enter STEM fields; and (2) promote the use of the All of Us Researcher Workbench to develop research focused on health equity. To achieve these goals, the program implements three key activities: (1) …

First Displaced Vertex Search For Electroproduced Dark-Sector Strongly Interacting Massive Particles By The Hps Experiment, P. H. Adrian, N. A. Baltzell, M. Battaglieri, M. Bondí, S. Boyarinov, C. Bravo, S. Bueltmann, P. Butti, V. D. Burkert, D. Calvo, T. Cao, M. Carpinelli, A. Celentano, G. Charles, L. Colaneri, W. Cooper, B. Crowe, C. Cuevas, A. D' Angelo, N. Dashyan, M. De Napoli, R. De Vita, A. Deur, M. Diamond, R. Dupre, H. Egiyan, T. Eichlersmith, L. Elouadrhiri, R. Essig, V. Fadeyev, C. Field, A. Filippi, A. Freyberger, S. Gaiser, M. Garçon, N. Gevorgyan, F. X. Girod, N. Graf, M. Graham, K. A. Griffioen, A. Grillo, M. Guidal, R. Herbst, M. Holtrop, J. Jaros, R. P. Johnson, G. Kalicy, M. Khandaker, V. Kubarovsky, E. Leonora, K. Livingston, L. Marsicano, T. Maruyama, S. Mccarty, J. Mccormick, B. Mckinnon, K. Moffeit, O. Moreno, C. Munoz Camacho, T. Nelson, S. Niccolai, A. Odian, R. O'Dwyer, M. Oriunno, M. Osipenko, R. Paremuzyan, S. Paul, E. Peets, N. Randazzo, B. Raydo, B. Reese, A. Rizzo, P. Schuster, Y. G. Sharabian, G. Simi, A. Simonyan, V. Sipala, A. Spellman, D. Sokhan, M. Solt, S. Stepanyan, H. Szumila-Vance, L. Tompkins, N. Toro, S. Uemura, M. Ungaro, H. Voskanyan, L. B. Weinstein, B. Wojtsekhowski

Physics Faculty Publications

The Heavy Photon Search experiment (HPS) is a fixed-target, electron beam experiment designed to search for 𝑒⁺⁢𝑒⁻ mass resonances and displaced decays using a forward acceptance spectrometer. This paper details the search for naturally long-lived “dark” vector mesons (𝑉_𝐷) arising from a dark sector of beyond-Standard-Model strongly interacting massive particles, characterized by a QCD-like 𝑆⁢𝑈⁢(3)_𝐷 symmetry and coupled to the Standard Model photon via a new 𝑈⁢(1)𝐷 gauge interaction mediated by the “heavy photon,” or 𝐴′. The results are based on an integrated luminosity of 10 608  nb⁻¹ collected during the 2016 HPS …

Real-Time Estimators For Scattering Observables: A Full Account Of Finite-Volume Errors For Quantum Simulation, Ivan M. Burbano, Marco A. Carrillo, Rana Urek, Anthony N. Ciavarella, Raul A. Briceno

Physics Faculty Publications

The real-time correlators of quantum field theories can be directly probed through new approaches to simulation, such as quantum computing and tensor networks. This provides a new framework for computing scattering observables in lattice formulations of strongly interacting theories, such as lattice quantum chromodynamics. In this paper, we prove that the proposal of real-time estimators of scattering observables is universally applicable to all scattering observables of gapped quantum field theories. All finite-volume errors are exponentially suppressed, and the rate of this suppression is controlled by the regulator considered, namely, a displacement of the spectrum of the theory into the complex …

Measuring Short-Range Correlations And Quasi-Elastic Cross Sections In A(E,E') At X > 1 And Modest Q², Y. P. Zhang, Z. H. Ye, D. Nguyen, P. Aguilera, Z. Ahmed, H. Albataineh, K. Allada, B. Anderson, D. Anez, K. Aniol, J. Annand, J. Arrington, T. Averett, H. Baghdasaryan, X. Bai, A. Beck, S. Beck, V. Bellini, F. Benmokhtar, A. Camsonne, C. Chen, J. -P. Chen, K. Chiraptpimol, E. Cisbani, S. Covid Dusa, M. M. Dalton, D. Day, W. Deconinck, M. Defurne, D. Flay, N. Fomin, M. Friend, E. Fuchey, F. Garibaldi, D. Gaskell, S. Gilad, R. Gilman, S. Glamazdin, C. Gu, P. Guèye, C. Hanretty, J. -O Hansen, M. Hashemi Shabestari, D. W. Higinbotham, M. Huang, S. Iqbal, G. Jin, N. Kalantarians, H. Kang, A. Kelleher, I. Korover, J. Lerose, J. Leckey, S. Li, R. Lindgren, E. Long, J. Mammei, P. Markowitz, D. Meekins, R. Michaels, M. Mihovilovič, N. Muangma, C. Munoz Camacho, B. E. Norum, Nuruzzaman, K. Pan, S. Phillips, E. Piasetzky, I. Pomerantz, M. Posik, V. Punjabi, X. Qian, Y. Qiang, X. Qiu, P. E. Reimer, A. Rakhman, S. Riordan, G. Ron, O. Rondon-Aramayo, L. Selvy, A. Shahinyan, R. Shneor, S. Širca, K. Slifer, N. Sparveris, R. Subedi, V. Sulkosky, D. Wang, J. W. Watson, L. B. Weinstein, B. Wojtsekhowski, S. A. Wood, I. Yaron, J. Zhang, Y. W. Zhang, B. Zhao, X. Zheng, P. Zhu, R. Zielinski

Physics Faculty Publications

We present results from the Jefferson Lab E08-014 experiment, investigating short-range correlations (SRC) through measurements of inclusive quasi-elastic scattering from ²H, ³He, ⁴He, ¹²C, ⁴⁰Ca, and ⁴⁸Ca. The kinematics were selected to isolate scattering from SRCs, yielding a plateau in the A/²H cross-section ratios due to the universal two-body structure of the 2N-SRCs in light and heavy nuclei. We observe approximate plateaus in the A/²H ratios and provide the first extractions of the A/²H ratio for ⁴⁰Ca and ⁴⁸Ca. We also examine the A/³He ratio, aiming to identify three-nucleon SRCs (3N-SRCs). Following the approach for isolating 2N-SRCs, searching for 3N-SRC …

Shock-Wave Structure In A Monatomic Gas Mixture With Rydberg Atoms, Anna Markhotok

Physics Faculty Publications

The effect of atom size on the shock-wave structure in a binary monatomic gas mixture with Rydberg atoms has been investigated. The problem was solved numerically using the system of hydrodynamic equations in argon gas for the atom-size ratios between 2 and 100, T = 1500 K, and the density between 10¹⁷ and 10²⁰ m−³. It was found that the presence of larger-sized atoms in the mixture results in shock front splitting that is on the order of the mean free path for this component. The results could be of interest in supersonic plasma dynamics and in astrophysics, studying shock …

Search For The Y(2175) In The Photoproduction Cross Section Measurement Of 𝛾p → 𝜙𝜋⁺𝜋⁻P At Gluex, F. Afzal, M. Albrecht, M. Amaryan, S. Arrigo, V. Arroyave, A. Asaturyan, A. Austregesilo, Z. Baldwin, F. Barbosa, J. Barlow, E. Barriga, R. Barsotti, D. Barton, V. Baturin, V. V. Berdnikov, A. Berger, W. Boeglin, M. Boer, W. J. Briscoe, T. Britton, R. Brunner, S. Cao, C. Chen, E. Chudakov, G. Chung, P. L. Cole, O. Cortes, V. Crede, M. M. Dalton, D. Darulis, A. Deur, S. Dobbs, A. Dolgolenko, M. Dugger, R. Dzhygadlo, D. Ebersole, M. Edo, H. Egiyan, P. Eugenio, A. Fabrizi, C. Fanelli, S. Fang, M. Fritsch, S. Furletov, L. Gan, H. Gao, A. Gardner, A. Gasparian, D. I. Glazier, C. Gleason, K. Goetzen, B. Grube, J. Guo, A. Hamdi, J. Hernandez, K. Hernandez, N. D. Hoffman, D. Hornidge, G. M. Huber, P. Hurck, W. Imoehl, D. G. Ireland, M. M. Ito, I. Jaegle, N. S. Jarvis, T. Jeske, M. Jing, R. T. Jones, V. Mateev, M. Mccaughan, M. Mccracken, C. A. Meyer, R. Miskimen, R. E. Mitchell, P. Moran, F. Nerling, L. Ng, E. Nissen, S. Orešić, A. I. Ostrovidov, Z. Papandeou, L. Pentchev, K. J. Peters, L. Puthiya Veetil, S. Rakshit, J. Reinhold, A. Remington, J. Ritman, G. Rodriguez, K. Saldana, S. Schadmand, A. M. Schertz, K. Scheuer, A. Schmidt, R. A. Schumacher, J. Schwiening, M. Scott, N. Septian, P. Sharp, V. J. Shen, X. Shen, M. R. Shepherd, J. Sikes, H. Singh, A. Smith, E. S. Smith, A. Somov, J. R. Stevens, I. I. Strakovsky, B. Sumner, K. Suresh, V. V. Tarasov, S. Taylor, Y. Teymurazyan, A. Thiel, M. Thomson, T. Viducic, T. Whitlatch, Y. Wunderlich, B. Yu, J. Zarling, Z. Zhang, X. Zhou, B. Zihlmann, The Glue X Collaboration

Physics Faculty Publications

Based on 334 pb-¹ of photoproduction data collected with the GlueX detector at Jefferson Lab, we have measured for the first time the cross section of the exclusive reaction 𝛾 + p → φ(1020)π⁺π⁻p by reconstructing the final state K⁺K⁻π⁺π⁻p produced with a photon beam of energies between 8.0 and 11.6 GeV. Based on the measured differential cross section, we have performed a search for the strangeoniumlike exotic candidate Y(2175), recently renamed to φ(2170). This state has been reported by different e⁺e⁻ annihilation experiments and it is addressed here for the first time in a photoproduction experiment. We do not …

Rf Design Progress Of The 197 Mhz Crab Cavity For Eic, B. Xiao, J. C. Brutus, A. Blednykh, Z. Conway, J. Cox, J. R. Delayen, S. U. De Silva, R. Fernandes, J. Guo, D. Holmes, N. Huque, G. Li, Z. Li, J. B. Mandel, S. Verdú-Andrés, G. Wang, Q. Wu, W. Xu

Physics Faculty Publications

The interaction region (IR) crab cavity system is a special RF system designed to compensate for the luminosity loss caused by the 25 mrad crossing angle at the interaction point (IP) of the Electron-Ion collider (EIC). The configuration includes six crab cavities in the Hadron (proton or ion) Storage Ring (HSR) - four operating at 197 MHz and two at 394 MHz - installed on each side of the IP, along with one 394 MHz crab cavity on each side of the IP in the Electron Storage Ring (ESR). This paper presents the recent progress in the RF design of …

Baryon-Antibaryon Photoproduction Cross Sections Off The Proton, F. Afzal, M. Albrecht, M. Amaryan, S. Arrigo, V. Arroyave, A. Asaturyan, A. Austregesilo, Z. Baldwin, F. Barbosa, J. Barlow, E. Barriga, R. Barsotti, D. Barton, V. Baturin, V. V. Berdnikov, A. Berger, W. Boeglin, M. Boer, W. J. Briscoe, T. Britton, R. Brunner, S. Cao, C. Chen, E. Chudakov, G. Chung, P. L. Cole, O. Cortes, V. Crede, M. M. Dalton, D. Darulis, A. Deur, L. Dietrich, S. Dobbs, A. Dolgolenko, M. Dugger, R. Dzhygadlo, D. Ebersole, M. Edo, H. Egiyan, P. Eugenio, A. Fabrizi, C. Fanelli, S. Fang, M. Fritsch, S. Furletov, L. Gan, H. Gao, A. Gardner, A. Gasparian, D. I. Glazier, C. Gleason, B. Grube, J. Guo, J. Hernandez, K. Hernandez, N. Herrmann, N. D. Hoffman, D. Hornidge, G. M. Huber, P. Hurck, W. Imoehl, D. G. Ireland, M. M. Ito, I. Jaegle, N. S. Jarvis, T. Jeske, M. Jing, R. T. Jones, V. Kayokan, G. Kalicy, X. Kang, V. Khachatryan, C. Kourkoumelis, A. Laduke, I. Larin, D. Lawrence, D. I. Lersch, H. Li, B. Liu, K. Livingston, L. Lorenti, V. Lyubovitskij, H. Marukyan, V. Matveev, M. Mccaughan, M. Mccracken, C. A. Mayer, R. Miskimen, R. E. Mitchell, P. Moran, L. Ng, E. Nissen, S. Orešić, A. I. Ostrovidov, Z. Papandreou, L. Pentchev, K. J. Peters, L. Puthiya Veetil, S. Rakshit, J. Reinhold, A. Remington, J. Ritman, G. Rodriguez, K. Saldana, S. Schadmand, A. M. Schertz, K. Scheuer, A. Schmidt, R. A. Schumacher, J. Schwiening, M. Scott, N. Septian, P. Sharp, V. J. Shen, X. Shen, M. R. Shepherd, J. Sikes, H. Singh, A. Smith, E. S. Smith, A. Somov, S. Somov, J. R. Stevens, I. I. Strakovsky, B. Sumner, K. Suresh, V. V. Tarasov, S. Taylor, A. Teymurazyan, A. Thiel, M. Thomson, T. Viducic, T. Whitlatch, Y. Wunderlich, B. Yu, J. Zarling, Z. Zhang, X. Zhou, B. Zihlmann

Physics Faculty Publications

The GLUEX experiment at Jefferson Lab has observed p(p) over bar and, for the first time, ΛΛ over bar and p Λ over bar photoproduction from a proton target at photon energies up to 11.6 GeV. The angular distributions are forward peaked for all produced pairs, consistent with Regge-like t-channel exchange. Asymmetric wide-angle antibaryon distributions show the presence of additional processes. In a phenomenological model, we find consistency with a double-t-channel exchange process where antibaryons are created only at the middle vertex. The model matches all observed distributions with a small number of free parameters. In the hyperon channels, we …

Forcing A Molecule To Switch: Quantifying Mechanical Control At The Atomic Scale, A. M. Shashika D. Wijerathna, Markus Zirnheld, Michael L. Hildebrand, Myles Perry, Marjorie Cenese, Yuan Zhang

Physics Faculty Publications

Mechanically induced conformational switching at the single-molecule level represents a fundamental mechanism for molecular functionality, yet quantitative characterization of the underlying force and energy landscape remains limited. Here, we study individual TBrPP-Co(II) molecules on Au(111) using qPlus atomic force microscopy. By reconstructing interaction potentials from 3D Δf(x,y,z) data, we determine a threshold force of ∼96 ± 8 pN and a tip-induced switching interaction energy of ∼38 ± 4 meV associate with the conformational transition. The isolated tip-molecule force follows a power law (exponent ∼6), indicating dominance of long-range van der Waals interactions. …

Inverse Problem In The Large Momentum Effective Theory Framework, Herve Dutrieux, Joe Karpie, Christopher J. Monahan, Kostas Orginos, Anatoly Radyushkin, David Richards, Savvas Zafeiropoulos

Physics Faculty Publications

One proposal to compute parton distributions from first principles is the large momentum effective theory (LaMET), which requires the Fourier transform of matrix elements computed nonperturbatively. Lattice quantum chromodynamics (QCD) provides calculations of these matrix elements over a finite range of Fourier harmonics that are often noisy or unreliable in the largest computed harmonics. It has been suggested that enforcing an exponential decay of the missing harmonics helps alleviate this issue. Using nonperturbative data, we show that the uncertainty introduced by this inverse problem in a realistic setup remains significant without very restrictive assumptions, and that the importance of the …

Real-Space Imaging Of The Electron-Pair Density Hole In Molecular Auger-Meitner Decay, Mats Simmermacher, Nathan Goff, Andres Moreno Carrascosa, Elke Fasshauer, Thomas Northey, Lingyu Ma, Haiwang Yong, Brian Stankus, Asami Odate, Xuan Xu, Wenping Du, Kyle Acheson, Joseph C. Cooper, Daniel Ratner, Mengning Liang, Ruaridh Forbes, Michael P. Minitti, Adam Kirrander, Peter M. Weber

Physics Faculty Publications

Electrons in matter can rearrange extremely quickly under external perturbations, underpinning subsequent structural and chemical transformations. Coulomb interactions between neighbouring electrons often shape this response, giving rise to correlated motion and strongly affecting the distribution of electrons in the system. Here we show that non-resonant hard X-ray scattering can directly access changes in the radial electron-pair density during the rapid rearrangement of core and valence electrons. We do this by studying sulfur hexafluoride molecules undergoing Auger–Meitner decay. We exploit a second-order interaction between the X-ray photons and the molecules to trigger and probe the decay dynamics with a single pulse, …

Exploring Causes Of Beam Loss At Cebaf, C. Matthews, J. Benesch, R. M. Bodenstein, B. Freeman, D. Moser, D. Turner, K. Price, J. Samari, B. Terzić

Physics Faculty Publications

At Jefferson Lab, the Continuous Electron Beam Accelerator (CEBAF) features a unique design with two linear accelerators and two arc sections allowing for multiple turns of the electron beam, as well as four experimental end stations. This topology leads to increased beam losses, especially in the spreader and recombiner regions connecting the arcs to the LINACs and in the extraction regions connecting the experimental end stations to the accelerator. These losses result in equipment activation and operational interruptions. Recent upgrades to the facility’s diagnostic systems, including the addition of xenon ion chambers, have provided higher-resolution data regarding these loss events. …

Efficient Dynamic And Momentum Aperture Optimization For Lattice Design Using Multipoint Bayesian Algorithm Execution, Z. Zhang, I. Agapov, S. Gasiorowski, T. Hellert, W. Neiswanger, X. Huang, D. Ratner

Physics Faculty Publications

We demonstrate that multipoint Bayesian algorithm execution (multipointBAX) can overcome fundamental computational challenges in storage ring design optimization. Dynamic aperture and momentum aperture optimization is a multipoint, multiobjective design task for storage rings, ultimately informing the flux of x-ray sources and luminosity of colliders. Current production black-box optimization methods require extensive particle-tracking simulations for each trial configuration; the high computational cost restricts the extent of the search to ~ 10³ configurations and therefore limits the quality of the final design. We remove this bottleneck using multipointBAX, which selects, simulates, and models each trial configuration at the single-particle level. We demonstrate …

School-Level Gaps In Mmr Coverage As The Fuel For Measles Outbreaks, Lamia Ayaz, Peter J Hotez, Seyed M Moghadas, Alison P Galvani

Faculty, Staff and Students Publications

No abstract provided.

Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits With Severe Acute Kidney Injury Successfully Managed By Clone-Directed Therapy: A Case Report, Hisashi Kamido, Yasuyuki Arai, Yayoi Ogawa, Naoka Murakami, Yuki Teramoto, Motoko Yanagita

Faculty, Staff and Students Publications

Introduction

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a form of monoclonal gammopathy of renal significance, characterized by kidney injury caused by monoclonal immunoglobulin deposition in the glomeruli. While detectable clones are only found in 20–30% of PGNMID, plasma cell- or B-cell-targeting therapies are suggested to be effective. Recent case reports suggested immune dysregulation, such as viral infections or vaccinations, could potentially trigger the onset or relapse of PGNMID. Here, we report a case of PGNMID without detectable clones, which relapsed after viral enteritis, presenting with severe acute kidney injury (AKI) and nephrotic syndrome.

Case Presentation

A 60-year-old man, …

Performance And Improvement Strategies For Adapting Generative Large Language Models For Electronic Health Record Applications: A Systematic Review, Ya-Wen Chuang, Yiming Li, Richard Yang, Pengyu Hong, David W Bates, Li Zhou

Faculty, Staff and Students Publications

Purpose: To synthesize performance and improvement strategies for adapting generative LLMs in EHR analyses and applications.

Methods: We followed the PRISMA guidelines to conduct a systematic review of articles from PubMed and Web of Science published between January 1, 2023 and November 9, 2024. Multiple reviewers including biomedical informaticians and a clinician involved in the article reviewing process. Studies were included if they used generative LLMs to analyze real-world EHR data and reported quantitative performance evaluations for an improvement technique. The review identified key clinical applications, summarized performance and the improvement strategies.

Results: Of the 18,735 articles retrieved, 196 met …

Partnerships To Advance Patient Safety And Address Preventable Harm: Case Studies From International Health Care Leaders, Susan Sheridan, David W Bates, Mark Mcclellan, Charles H Kahn, Eyal Zimlichman

Faculty, Staff and Students Publications

There have been notable improvements in patient safety in recent years; however, significant challenges remain in reducing the incidence of preventable patient harm. Supporting patient safety efforts is increasingly important given increasing complexity of care and changing health needs, especially with aging populations. Emerging technologies and capabilities open new possibilities to address longstanding patient safety problems. For example, predictive analytics to support provider decision-making, increased patient interest in engagement in their care, and artificial intelligence provide opportunities to further reduce harm. Many of these examples support a more proactive approach to patient safety by focusing on anticipating, predicting, and preventing …

External Validation Of A Machine Learning Model To Predict Postpartum Hemorrhage In A Us Northeastern Healthcare System, Kartik K Venkatesh, Eric Jelovsek, David W Bates, Kathryn J Gray

Faculty, Staff and Students Publications

Introduction: Postpartum hemorrhage (PPH) is a major cause of maternal morbidity and mortality. Timely prediction may prevent adverse maternal outcomes, and efforts are needed to develop accurate predictive tools. A high-performing machine learning model to predict PPH using data from the US Consortium for Safe Labor (CSL) remains to be widely validated in contemporary clinical settings using electronic health record (EHR) data. Our goal was to evaluate the performance of the CSL PPH predictive model using EHR data across a large healthcare system in the Northeastern United States.

Methods: We conducted a retrospective cohort study across eight hospitals in the …

Smokejumper Magazine, January 2026, National Smokejumper Association

Smokejumper and Static Line Magazines

This issue of the National Smokejumper Association (NSA) Smokejumper Magazine, contains the following articles:

Message from the President; Smokejumpers in Indochina; Visionary in Aisle Three!; 2025 NSA Scholarship and Education/Training Grant Awardees; The Greatest Generation; You can Get Great Firefighters; You Just Have to Work for It; Bagger Crew; The OC Fire Program: A Fire Path to Life; The Summer My Life Changed; Only In Alaska; Burned Out: It Doesn't Have to Be This Way; Jumpin' at 300 Feet; 56 Years Later; Round vs. Square; Featured Member: Ken Herrick; Notes From the Ranks; Thoroughly Modern McCall; Sounding Off; Odds and …

Annual Report Of The Town Of Enfield, New Hampshire Year Ending December 31, 2025, Enfield Town Representatives

Enfield, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Forest Island Reforestation In The Llanos De Moxos, Bolivia, Ethan Tam

Graduate Studies Theses and Dissertations 2026

Within the Llanos de Moxos of Bolivia thousands of forest islands dot the landscape. These forest islands have been shown to have been integral aspects of the pre-Contact indigenous cultures which existed there for thousands of years. Based on 1967 CORONA imagery and statistical analysis, this work provides insight into how these forest islands are integrated as infrastructure features within their landscape and surrounding network of other archaeological features. This research is carried out through investigations into changes in the size of the forest islands across an interval of 57 years, statistical attempts to categorize the forest island into smaller …

Government Agencies In The United States Are Obstructing Native Species Restoration, Creating Regulatory Pits For Wildlife, Jeremy T. Bruskotter, L. Mark Elbroch, John Vucetich

Michigan Tech Publications

No abstract provided.