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Articles 64651 - 64680 of 64705
Full-Text Articles in Entire DC Network
Information-Processing Gap And Insider Trading Profitability: Evidence From The Xbrl Mandate, Yuyun Huang, Jerry T. Parwada, Yuan George Shan, Joey W. Yang
Information-Processing Gap And Insider Trading Profitability: Evidence From The Xbrl Mandate, Yuyun Huang, Jerry T. Parwada, Yuan George Shan, Joey W. Yang
Research outputs 2022 to 2026
The information processing costs faced by external investors may provide corporate insiders with a comparative advantage. We examine how the phased introduction of the eXtensible Business Reporting Language (XBRL) mandate, designed to lower investors' costs of processing public disclosures, affects insiders’ trading profitability. We find that opportunistic insider sales, but not purchases, become significantly less profitable following the first wave of mandatory XBRL adoption. This decline is consistent with a reduced number of insider sales preceding 10-K filings that convey unfavorable news, as well as with a general fall in insider trading activity and profitability across all three mandate waves. …
Invertivore Fish Predation Is An Overlooked Source Of Carbonate Sediment On A Turbid Coral Reef, Jake L. Nilsen, Nicola K. Browne, Kyle M. Morgan, Joshua L. Bonesso, Dylan Benson, Shannon Dee, Michael J. O’Leary, Lisa A. Kirkendale, Peter U. Middelfart, Michael V.W. Cuttler, Jennifer L. Mcilwain
Invertivore Fish Predation Is An Overlooked Source Of Carbonate Sediment On A Turbid Coral Reef, Jake L. Nilsen, Nicola K. Browne, Kyle M. Morgan, Joshua L. Bonesso, Dylan Benson, Shannon Dee, Michael J. O’Leary, Lisa A. Kirkendale, Peter U. Middelfart, Michael V.W. Cuttler, Jennifer L. Mcilwain
Research outputs 2022 to 2026
The geomorphic stability of coral reef islands depends on a continued supply of biologically derived sediment from reefs. However, the ecological processes that produce detrital sediment remain poorly resolved. The role of fishes as sediment producers has largely focused on coral sand generated by parrotfishes (Labridae: Scarinae) in clear-water settings, while the contribution of other groups, such as durophagous invertivores, remains poorly understood. Here, we quantify the contribution of invertivores to carbonate sediments at an inshore reef in the Exmouth Gulf, Western Australia, by combining fish census data and dietary analysis, coupled with taphonomic and compositional analysis of benthic sediments. …
It's The Most Diverse Job I’Ve Ever Had: What Do Registered Nurses Working In Australian Schools Do?, Anita Moyes
It's The Most Diverse Job I’Ve Ever Had: What Do Registered Nurses Working In Australian Schools Do?, Anita Moyes
Research outputs 2022 to 2026
Although nurses have been working in Australian schools for many decades, research has focused primarily on narrow aspects of clinical practice or service delivery in specific regions. The aim of this study was to identify the domains of practice registered nurses report in a typical working day in Australian schools, using interview data from a national sample. Forty-five nurses working in government and nongovernment schools in every state and territory of Australia participated. Interviews were analyzed using inductive content analysis ( Elo & Kyngas, 2008). Six distinct domains of practice characterized nursing work in Australian schools: (i) responding to diverse …
Knowledge, Intentions And Attitudes Towards Osteoporosis And Other Health Conditions Among Older Australians, Phuong Dung Lam, Satvinder S. Dhaliwal, Christina M. Pollard, Jonine M. Jancey, Richard L. Prince, Deborah A. Kerr
Knowledge, Intentions And Attitudes Towards Osteoporosis And Other Health Conditions Among Older Australians, Phuong Dung Lam, Satvinder S. Dhaliwal, Christina M. Pollard, Jonine M. Jancey, Richard L. Prince, Deborah A. Kerr
Research outputs 2022 to 2026
Background: Osteoporosis burden is underdiagnosed and undertreated. While increasing community awareness and education are recognised priorities, research on how older adults view osteoporosis is limited. The aim was to assess osteoporosis-related knowledge, intentions and attitudes in relation to other health conditions in Australian adults aged 50 years and older.
Methods: A validated online questionnaire, developed with an expert panel, was administered to 1432 healthy volunteers, (64.3 ± 9.5 years). The questionnaire assessed knowledge of osteoporosis risk factors, attitudes and intentions. Multivariable logistic regression identified factors associated with low knowledge.
Results: Knowledge score across six topics was 29.5 ± 14.5 (100 …
Living On Display: Reciprocal Gazes, Everyday Encounters, And The Politics Of Visibility In The Sunshine Coast Tourism Community, Madura Thiwanka Pathirana, Noel Scott
Living On Display: Reciprocal Gazes, Everyday Encounters, And The Politics Of Visibility In The Sunshine Coast Tourism Community, Madura Thiwanka Pathirana, Noel Scott
Research outputs 2022 to 2026
This community case study analyses the production, negotiation, and contestation of reciprocal gazes within everyday settings, particularly focusing on contemporary lifestyle tourism destinations, and the examination of the Sunshine Coast, Australia. Based on 48 in-depth interviews with tourists and locals, this case study looks at the politics of visibility that are part of host-guest relations in everyday encounters at the beach, cafe, marketplace, and online-mediated market. Intersecting with critical tourism studies, and tourism studies on the traveler, host, and reciprocal gaze, this study focuses on residents' experiences of being observed, judged, and photographed and the impacts of their experiences on …
Mechanisms Influencing Maximum Joint Range Of Motion And Stiffness: A Narrative Review, Camila D. Lima, Anthony J. Blazevich
Mechanisms Influencing Maximum Joint Range Of Motion And Stiffness: A Narrative Review, Camila D. Lima, Anthony J. Blazevich
Research outputs 2022 to 2026
Joint ‘flexibility’ is an encompassing term influenced by both a joint’s maximum range of motion (ROMmax) and its resistance to rotation, i.e. its stiffness. A critical amount of flexibility is thought to be important for both sports performance and daily and occupational tasks. Improvements in joint ROMmax, specifically, are often assumed to result from material and mechanical changes in the joint’s soft tissue structures; however, they also may result from changes in sensory information relayed from peripheral receptors to the brain, or the interpretation of that information. Changes in psychological state mediated by pain, state arousal and other psychological factors …
Modifiable Risk Factors And Hearing Loss: The National Health And Nutrition Examination Survey 1999–2020, Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li
Modifiable Risk Factors And Hearing Loss: The National Health And Nutrition Examination Survey 1999–2020, Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li
Research outputs 2022 to 2026
Objective: To explore the associations between major modifiable risk factors and hearing loss.
Methods: This serial cross-sectional study was conducted within the National Health and Nutrition Examination Survey 1999–2020 in the United States. Associations were assessed using modified Poisson regression and within-sample population attributable fraction (PAF).
Results: Eight thousand seven hundred and seventy adults aged 40–85 years were included in the analyses, the mean (SD) age was 58.0 (11.7) years, with 4002 men (45.6%). Hearing loss was associated with low educational attainment with prevalence ratio 1.23, 95% confidence interval (1.15, 1.31); low income 1.11 (1.04, 1.19); diabetes 1.10 (1.03, 1.18); …
Music Teacher Wellbeing And Flourishing In Australian Primary Schools, Han Meng, Jason Goopy, Narelle Lemon
Music Teacher Wellbeing And Flourishing In Australian Primary Schools, Han Meng, Jason Goopy, Narelle Lemon
Research outputs 2022 to 2026
Teacher wellbeing is often generalised across roles, while a nuanced understanding of specialist teachers is often overlooked. This study used the positive psychology strengths-based PERMAH model to investigate factors that support wellbeing and flourishing of primary school music teachers in Australia and opportunities for growth. As part of a larger mixed-methods research project, data for this article were generated through interviews with 14 music teachers who deliver primary school class music and were analysed using reflexive thematic analysis. Findings indicated that music teacher wellbeing was promoted by joy derived from students’ learning, passion for teaching music, and recognition and support …
Nothing Else Matters: Why Relationships May Be Key To Establishing Healthy Eating Behaviours In Young Children, Therese A. O’Sullivan, Kathryn G. Di Candilo
Nothing Else Matters: Why Relationships May Be Key To Establishing Healthy Eating Behaviours In Young Children, Therese A. O’Sullivan, Kathryn G. Di Candilo
Research outputs 2022 to 2026
Food is more than its nutritional components. It brings people together, and connects us to family, culture, and heritage. The development of eating habits and relationships with food begins in infancy and continues across the lifespan. Echoing the theme of Metallica’s 72 Seasons, which was being toured in Australia when this work was presented, experiences during the early years may shape later patterns of behaviour and identity. This can include mindsets around food and eating. This review aims to explore how early life parent/caregiver feeding practices may impact this development of children’s eating behaviours. A respectful and responsive approach to …
Nurses' Perceptions Of Their Non-Technical Skills In Recognising And Responding To Clinical Deterioration In Hospital Settings: A Systematic Review, Darlene Archer, Amineh Rashidi, Rajbeer Kaur, Allison Roderick, Olivia Gallagher
Nurses' Perceptions Of Their Non-Technical Skills In Recognising And Responding To Clinical Deterioration In Hospital Settings: A Systematic Review, Darlene Archer, Amineh Rashidi, Rajbeer Kaur, Allison Roderick, Olivia Gallagher
Research outputs 2022 to 2026
Aim: To understand nurses' perceptions of non-technical skills in recognising and responding to clinical deterioration in hospital settings.
Design: A mixed methods systematic review was undertaken, guided by the Joanna Briggs Institute Manual for Evidence Synthesis.
Methods: A systematic search of the primary research literature published between 2012 and October 2025 was undertaken. A convergent integrated approach to synthesis, without meta-analysis, was undertaken.
Data Sources: The MEDLINE, CINAHL, Scopus, PsychInfo and Embase electronic databases were searched. Reference lists of full-text articles retrieved were reviewed for additional data sources.
Results: Twenty-four primary studies were included. Narrative synthesis resulted in six main …
Practising Digital Product Passport For Circular Supply Chain: Ecosystem Orchestration Perspective, Martin Agyemang, Daniel Faibil, Richard Asante, Cristina Iodice
Practising Digital Product Passport For Circular Supply Chain: Ecosystem Orchestration Perspective, Martin Agyemang, Daniel Faibil, Richard Asante, Cristina Iodice
Research outputs 2022 to 2026
Digital product passports (DPP) are emerging as an important tool to support industries in realising circular supply chain (CSC) practices. However, small and medium-sized enterprises (SMEs) remain constrained by various challenges in implementing DPP. Therefore, using social practice theory and ecosystem orchestration perspective, the study identifies factors essential for DPP-enabled CSC implementation by SMEs. The study proposes an actionable framework to classify and operationalise these factors. We collected data from managers and analysed it using the Best–Worst Method and Fuzzy-DEMATEL to understand the interdependence, coordination and temporal adaptation of the factors. The findings show that material factors are particularly salient …
Protomix: Unified Prototype Learning For Semantic Change Detection In Remote Sensing, Hengzhi Chen, Kun Hu, Patrick Filippi, Wei Xiang, Thomas Francis Bishop, Zhiyong Wang
Protomix: Unified Prototype Learning For Semantic Change Detection In Remote Sensing, Hengzhi Chen, Kun Hu, Patrick Filippi, Wei Xiang, Thomas Francis Bishop, Zhiyong Wang
Research outputs 2022 to 2026
As an emerging topic, semantic change detection (SCD) in remote sensing aims to both identify the locations of changes before and after events and determine the land cover (LC) classes of changed regions. While deep learning has demonstrated its great potential for SCD, the following two fundamental challenges remain: large variations among the same LC class as well as close similarity between different LC classes, and the severe underutilization of massive unchanged regions, which dominate remote sensing scenes but lack detailed semantic annotations. To address these issues, we propose a novel prototype learning framework for SCD, namely ProtoMix, by leveraging …
Determinants Of Artificial Intelligence Adoption: Research Themes And Future Directions, Ahmad A. Khanfar, Reza Kiani Mavi, Mohammad Iranmanesh, Denise Gengatharen
Determinants Of Artificial Intelligence Adoption: Research Themes And Future Directions, Ahmad A. Khanfar, Reza Kiani Mavi, Mohammad Iranmanesh, Denise Gengatharen
Research outputs 2022 to 2026
The adoption of artificial intelligence (AI) systems is on the rise owing to their many benefits. This study conducted a bibliometric analysis to identify (1) how the literature on AI adoption has evolved over the past few years, (2) key themes associated with AI adoption in the literature, and (3) the gaps in the literature. To achieve these objectives, we utilised the Biblioshiny of R-package bibliometric analysis tool to analyse the AI adoption literature. A total of 91 articles were reviewed and analysed in this study. Four major themes were identified: AI, machine learning, the unified theory of acceptance and …
Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang
Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang
Research outputs 2022 to 2026
Purpose: This study emphasizes the growing significance of destination attributes in shaping the experiences and behaviours of gastronomy and culinary tourists. Understanding both core and complementary attributes of a gastronomy tourism destination is crucial for its sustainable development. However, there is a lack of a reliable measurement for tourists’ perceived attributes of gastronomy tourism destinations (PAGTD). Therefore, the purpose of this study is to develop a scale to measure tourists’ PAGTD. Design/methodology/approach: The study systematically followed the scale development and validation process, using three samples (Sample 1, n = 200; Sample 2, n = 204; and Sample 3, n = …
A Figurational Analysis Of Health And/Or Physical Education Teacher Educators’ Conceptualisations Of Policy, And Their Sociogenesis, Laura Alfrey, Dylan Scanlon, David Aldous, Jenna Lorusso, Kellie Baker, Christopher Clark, Mo Jafar
A Figurational Analysis Of Health And/Or Physical Education Teacher Educators’ Conceptualisations Of Policy, And Their Sociogenesis, Laura Alfrey, Dylan Scanlon, David Aldous, Jenna Lorusso, Kellie Baker, Christopher Clark, Mo Jafar
Research outputs 2022 to 2026
Policy engagement is key to promoting quality physical education yet it has been identified as a ‘grand challenge’ for Health and/or Physical Education (H/PE) internationally. All H/PE professionals, including teacher educators, have a collective responsibility to engage with policy but existing research tells us little about how H/PE teacher educators (H/PETEs) understand and engage with policy. It is important to examine H/PETEs conceptualisations of policy for a few reasons, not least because teacher educators play a crucial role in supporting future generations of teachers who themselves will need to engage with policy as a core feature of their professional lives. …
The Transformational Possibilities Of Liberal Vocationalism: A Case Study Of Post-Year 10 Outdoor Education In Western Australia, David Aldous, Dawn Penney
The Transformational Possibilities Of Liberal Vocationalism: A Case Study Of Post-Year 10 Outdoor Education In Western Australia, David Aldous, Dawn Penney
Research outputs 2022 to 2026
This paper discusses the transformative potential that liberal vocationalism, aligned with contemporary visions of lifelong and lifewide learning, presents for outdoor learning across institutional and industry settings. Utilising Bernstein’s sociological theory, the paper explores this transformation through an illustrative case study of the relations, knowledges and identities of post-Year10 Outdoor Education in Western Australia (WA). The case study highlights how Outdoor Education in WA has been organised through distinct classificatory relations that exist between government, regulatory bodies and individual industry providers that serve to distinguish Outdoor Education from outdoor learning that is ongoing and able to be pursued by people …
The “Green Persuasion Effect” Of Negative Messages: How And When Message Framing Influences Tourists’ Environmentally Responsible Behavior, Xuehuan He, Chengzhi Ye, Songshan Huang, Lujun Su
The “Green Persuasion Effect” Of Negative Messages: How And When Message Framing Influences Tourists’ Environmentally Responsible Behavior, Xuehuan He, Chengzhi Ye, Songshan Huang, Lujun Su
Research outputs 2022 to 2026
Tourist activities may harm the environment, making tourists’ environmentally responsible behavior particularly important in tourism research. This research investigates the persuasion effect of message framing in environmental protection reminders on environmentally responsible behavior. Through five studies employing both field and controlled experiments and different measures of environmentally responsible behavior across varied tourism scenarios, we demonstrate that negatively (vs. positively) framed messages more effectively increase environmentally responsible behavior. Specifically, negatively framed messages are more effective in enhancing tourists’ environmental awareness, which triggers more environmentally responsible behavior. Furthermore, we identify social class as a moderator of message framing effectiveness, showing that negatively …
Cytocompatibility, Osteogenic Potential, Antibacterial And Antibiofilm Efficacy Of A Calcium-Silicate-Based Intracanal Medication, Shehabeldin Mohamed Saber Prof.Dr.
Cytocompatibility, Osteogenic Potential, Antibacterial And Antibiofilm Efficacy Of A Calcium-Silicate-Based Intracanal Medication, Shehabeldin Mohamed Saber Prof.Dr.
Dentistry
This study assessed the biological and antimicrobial properties of a calcium silicate-based material and calcium hydroxide (CH) when used as intracanal medications. MTT assay, osteogenic differentiation of human periodontal stem cells (hPDLSCs), cell mineralization-assay, and determination of ALP activity were assessed to investigate the biological properties. While the agar well diffusion, crystal violet (CRV) assay and LIVE/DEAD staining of dentin slices infected with a mature E. faecalis biofilm were used to assess the antimicrobial properties. Normally distributed data were analyzed using one and two-way ANOVA and post hoc Tukey test, while for non-normally distributed data Kruskal Wallis and Dunn's tests …
Automatic Teeth Segmentation In Panoramic Radiographs Using Attention U-Net, Shehabeldin Mohamed Saber Prof.Dr.
Automatic Teeth Segmentation In Panoramic Radiographs Using Attention U-Net, Shehabeldin Mohamed Saber Prof.Dr.
Dentistry
Aim: The aim of this study is to investigate the effectiveness of the Attention U-Net architecture for teeth segmentation in panoramic dental images. By exploring the potential of Attention U-Net, the study aims to contribute to the development of more precise and automated dental imaging analysis, which could enhance diagnosis, treatment planning, and computer-aided dental systems. Subjects and methods: The TUFTS University dataset consisting of 1000 de-identified panoramic radiographs was used for training and testing an Attention U-Net architecture with 10-fold cross-validation. These scores surpass those of all other networks implemented on the same dataset. using a newly available benchmark …
Dual Regulation Of Osteogenesis And Inflammation By Pomegranate (Punica Granatum L.) Extract In Periodontal Ligament-Derived Stem Cells: Implications For Regenerative Medicine, Mai Hafez
Dentistry
Objectives
This article aims to compare the osteogenic along with anti-inflammatory activity of different concentrations of pomegranate extract (PG) on human periodontal ligament-derived stem cells (hPDLSCs) in vitro.
Materials and Methods
hPDLSCs were acquired from the root surface of removed molars, cultured, and then distinguished by flow cytometry analysis and several lineage differentiation potentials. To identify the effect of PG on hPDLSCs' viability, an MTT assay was performed. hPDLSCs were maintained in osteogenic induction medium with varying concentrations of PG. At the end of the induction period, osteogenesis was assessed using Alizarin Red staining, ALP assay, and qRT-PCR to determine …
The Effects Of Cigarette Smoke And Heated-Tobacco Aerosol On Streptococcus Mutans Adhesion And Surface Topography Of Dental Hard Tissues In Vitro, Mahmoud Bakr, Mohamed Shamel, Mahmoud Al Ankily
The Effects Of Cigarette Smoke And Heated-Tobacco Aerosol On Streptococcus Mutans Adhesion And Surface Topography Of Dental Hard Tissues In Vitro, Mahmoud Bakr, Mohamed Shamel, Mahmoud Al Ankily
Dentistry
No abstract provided.
The Effects Of Cigarette Smoke And Heated-Tobacco Aerosol On Streptococcus Mutans Adhesion And Surface Topography Of Dental Hard Tissues In Vitro, Mohamed Shamel, Mahmoud Al Ankily, Nourhan Taha
The Effects Of Cigarette Smoke And Heated-Tobacco Aerosol On Streptococcus Mutans Adhesion And Surface Topography Of Dental Hard Tissues In Vitro, Mohamed Shamel, Mahmoud Al Ankily, Nourhan Taha
Dentistry
No abstract provided.
Stress Distribution In Different Toothimplant Supported Mandibular Prostheses Rehabilitating Unilateral Free-End Saddle: A Biomechanical Comparative Finite Element Study, Maha Nagy Kamal, Haytham Amr Mohammed, Abdallah Shokkry
Stress Distribution In Different Toothimplant Supported Mandibular Prostheses Rehabilitating Unilateral Free-End Saddle: A Biomechanical Comparative Finite Element Study, Maha Nagy Kamal, Haytham Amr Mohammed, Abdallah Shokkry
Dentistry
Abstract Aim of the study Utilizing Finite Element Analysis, this research biomechanically assessed three prosthetic designs for mandibular unilateral free-end saddle, specifically interrogating the magnitude and distribution of stresses transmitted to the terminal anterior abutment and the supporting posterior implant. Materials and methods A mandibular unilateral free-end saddle educational cast, with the first premolar as the last standing abutment tooth, was used. The abutment teeth of the free end saddle side were prepared to accommodate two splinted crowns. Then the cast was scanned, and an implant analogue was digitally inserted at the second molar area using Blender4dental software. Three different …
Anticancer Effects Of A Captopril Montmorillonite Formulation In Oral Cancer Cells Through Apoptosis And Redox Modulation, Dalia Ghalwash, Nada Saleh, Hadeel Mousa, Shereen Raafat
Anticancer Effects Of A Captopril Montmorillonite Formulation In Oral Cancer Cells Through Apoptosis And Redox Modulation, Dalia Ghalwash, Nada Saleh, Hadeel Mousa, Shereen Raafat
Dentistry
Abstract Background Oral squamous cell carcinoma (OSCC) remains challenging due to the limited efficacy and toxicity of current therapies. This study investigates the anticancer potential of Captopril–Montmorillonite (CP–MMT) (nanoclay-based delivery system), a drug-repurposing approach in which Captopril is incorporated within MMT nanoclay layered silicate carrier. To our knowledge, this formulation has not been previously investigated in OSCC cell lines, demonstrating enhanced anticancer efficacy. The aim of the work was to compare the anticancer effects of CP–MMT formulation with free Captopril in OSCC cell lines, focusing on cytotoxicity, apoptosis, cell-cycle arrest, oxidative stress, and key molecular markers. Methods CP–MMT nanoclay-based formulation …
Bone Dimensional Stability With Versus Without A Stent Following Apically Repositioned Flap And Single-Stage Implant Placement: A Randomized Clinical Trial, Dalia Ghalwash, Ahmed Hamdy, Jazia Alblowi
Bone Dimensional Stability With Versus Without A Stent Following Apically Repositioned Flap And Single-Stage Implant Placement: A Randomized Clinical Trial, Dalia Ghalwash, Ahmed Hamdy, Jazia Alblowi
Dentistry
Abstract Maintaining peri-implant bone and tissue health is essential for long-term implant success. The effectiveness of adjunctive stent stabilization is still unclear, though the apically repositioned flap (ARF) improves soft tissue conditions. Therefore, this study assessed whether the use of stents during single-stage placement improves peri-implant bone changes and clinical outcomes following ARF. This randomized clinical trial included twenty partially edentulous patients who were divided into two groups: ARF with stent stabilization (n = 10) and ARF using conventional suturing (n = 10). At baseline, three months, and six months, radiographic bone dimensions measured by cone-beam computed tomography (CBCT) were …
Clinical Feasibility Of An Artificial Intelligence- Assisted Digital Workflow For Full-Arch Implant Rehabilitation: A Multicenter Case Series, Dalia Ghalwash, Marco Tallarico, Mohamed El Ashry, Carlotta Cacciò, Mohamad Qaddomi
Clinical Feasibility Of An Artificial Intelligence- Assisted Digital Workflow For Full-Arch Implant Rehabilitation: A Multicenter Case Series, Dalia Ghalwash, Marco Tallarico, Mohamed El Ashry, Carlotta Cacciò, Mohamad Qaddomi
Dentistry
Fully digital workflows are increasingly used in implant prosthodontics; however, completely edentulous full-arch rehabilitations remain challenging because implant position transfer and passive framework fit are susceptible to cumulative scanning and registration errors. Clinical evidence on artificial intelligence (AI)-assisted completearch implant impression workflows remains limited. This multicenter case series aimed to describe the clinical feasibility of an AI-assisted digital workflow (SmartX) combined with extended scan bodies for all-on-X full-arch implant-supported rehabilitations. Ten completely edentulous patients rehabilitated with all-on-X implant-supported fullarch prostheses were included. Digital impressions were obtained using SmartFlag scan bodies and an AI-assisted SmartX workflow with an intraoral scanner. The …
Chia Seed Extract As A Potential Adjunct In The Management Of Oral Candidiasis: An In Vitro Study, Dalia Ghalwash, Rawda Sayed, Ahmed Ammar, Eman Khalil
Chia Seed Extract As A Potential Adjunct In The Management Of Oral Candidiasis: An In Vitro Study, Dalia Ghalwash, Rawda Sayed, Ahmed Ammar, Eman Khalil
Dentistry
ABSTRACT Background Oral candidiasis remains a common opportunistic fungal infection, with increasing interest in natural antifungal alternatives. This study aimed to evaluate the antifungal activity of Salvia hispanica (chia) seed extract against oral Candida albicans, compare its efficacy with nystatin, assess their combined effect, and investigate cytotoxicity on WI-38 human fibroblast cells. Methods Antifungal activity was evaluated using broth microdilution and agar well diffusion assays, with nystatin oral suspension used as a positive control. Cytotoxicity of chia seed extract was assessed on WI-38 human fibroblast cells using the MTT assay. Results Chia seed extract demonstrated notable antifungal activity, with a …
Evaluation Of Periodontal Parameters Among Infertile Men Undergoing Periodontitis Treatment: A Retrospective Study, Dalia Ghalwash, Rim Ghanem, Mazen Ghanem, Manal Safan, Ahmed Ghanem
Evaluation Of Periodontal Parameters Among Infertile Men Undergoing Periodontitis Treatment: A Retrospective Study, Dalia Ghalwash, Rim Ghanem, Mazen Ghanem, Manal Safan, Ahmed Ghanem
Dentistry
Background and Objectives: Periodontitis has been linked to idiopathic male infertility and impairment of semen values. However, data on the role of periodontal treatment in sperm parameter outcomes as well as the identification of the value of clinical periodontal infection predictors (BOP, PD, and CAL) as composite measures following active periodontitis therapy are limited. This study aimed to evaluate the role of periodontitis treatment in infertile men and its impact on semen quality. Methods: 58 infertile patients with semen abnormalities underwent treatment of periodontitis. Clinical periodontal and andrological examinations were conducted for all participants. Clinical periodontal parameters (PD, BOP, and …
Targeting Of The Oncogenic Fusion Ewsr1-Fli1 In Ewing Sarcoma By Crispr/Dcas9 Silencers, Shahama Taifour, Chee Wai Wong, Christopher Wallis, Edina Wang, Ash W.J. Tie, Eleanor Woodward, Charlene Waryah, Mahnaz Hosseinpour, Dilys Lam, Ryan Lister, Larissa Dymond, Andrew Woo, Peter J. Houghton, K. Swaminathan Iyer, Marck Norret, Cameron W. Evans, Louise Winteringham, Silvana Gaudieri, Pilar Blancafort
Targeting Of The Oncogenic Fusion Ewsr1-Fli1 In Ewing Sarcoma By Crispr/Dcas9 Silencers, Shahama Taifour, Chee Wai Wong, Christopher Wallis, Edina Wang, Ash W.J. Tie, Eleanor Woodward, Charlene Waryah, Mahnaz Hosseinpour, Dilys Lam, Ryan Lister, Larissa Dymond, Andrew Woo, Peter J. Houghton, K. Swaminathan Iyer, Marck Norret, Cameron W. Evans, Louise Winteringham, Silvana Gaudieri, Pilar Blancafort
Research outputs 2022 to 2026
Despite the revolutionary impact of genome engineering tools in medicine, the safe and effective intracellular delivery of CRISPR remains a major obstacle to clinical applications. Here, we utilize precision molecular targeting and delivery strategies based on CRISPR-nuclease-dead Cas9 (dCas9) systems adapted for epigenetic repression (dCas9-Krüppel-associated box [KRAB]) to silence oncogenic drivers with high selectivity. As proof of principle, we target the EWSR1-FLI1 translocation, which encodes a chimeric and hard-to-drug oncogenic transcription factor driving approximately 85% of the cases of Ewing sarcoma (EWS)—an aggressive childhood malignancy. We describe the development of a programmable, non-viral polymeric system for the delivery of dCas9-KRAB …
Example Imagery Survey Data And Project Files To Test Wisdam Software, Amanda Hodgson, Christophe Cleguer
Example Imagery Survey Data And Project Files To Test Wisdam Software, Amanda Hodgson, Christophe Cleguer
Research Datasets
This example dataset is designed to support our WISDAM (Wildlife Image Survey Detection and Mapping) software—a free, open‑source application (available at www.WISDAMapp.org) created for researchers conducting wildlife imagery surveys. WISDAM enables users to generate data suitable for abundance estimation and spatial modelling from aerial photographic surveys of marine and terrestrial megafauna.