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2026

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Reclaiming Agency: Ai Hallucinations And Translingual Interrogations In The City Tech Writing Center,, Joseph Franklin, Anna Laura Falvey Jan 2026

Reclaiming Agency: Ai Hallucinations And Translingual Interrogations In The City Tech Writing Center,, Joseph Franklin, Anna Laura Falvey

Publications and Research

No abstract provided.


Infection Control Across Clinical And Laboratory Dental Settings Protocols, Risks, And The Role Of Emerging Technologies, Khrystyna Vyprynyuk, Laura Andreesku Jan 2026

Infection Control Across Clinical And Laboratory Dental Settings Protocols, Risks, And The Role Of Emerging Technologies, Khrystyna Vyprynyuk, Laura Andreesku

Publications and Research

This article explores infection prevention strategies and disease transmission pathways in dental settings, emphasizing the critical connection between clinical practice and dental laboratories. It highlights the risks of cross-contamination, disinfection and sterilization challenges, and the growing role of technology in enhancing infection control.


Archives And Children's Knowledge, Elliott Kuecker, Ashley Rockenbach Jan 2026

Archives And Children's Knowledge, Elliott Kuecker, Ashley Rockenbach

Publications and Research

This article argues for the importance of collecting works created by children—not just about and not just for—in formal archival collections. Framed through the ideas of legitimate knowledge and epistemic injustice, this piece combines notions important to children’s rights activists and childhood studies scholars with the role archives can play in preserving children’s knowledge through child-created materials. The authors describe how researchers struggle to find work created by children within archives, impacting the ability to create child-centered research that centers children’s views of the world as prominently as adult views of the world. Some collections that do include child-created materials …


Hidden In The Mist: Three New Species Of Salamanders Of The Genus Pseudoeurycea (Amphibia: Plethodontidae) From Oaxaca, Mexico, Eduardo A. Aguilar-Herrera, Salomón Sanabria-Urbán, Dulce L. Flores-Martínez, José David Gómez-Tapia, Misael Seba-Chacha, Leopoldo D. Vázquez-Reyes, Francisco A. Rivera-Ortíz, Patricia Ramírez-Bastida, Bruno Cortés-Ortiz, R. Alejandro Calzada-Arciniega, Etienne U. Avila-Ortega, Dónovan I. Víquez-Vega, Omar Hernández-Ordoñez, Christopher Blair, Víctor H. Jiménez-Arcos Jan 2026

Hidden In The Mist: Three New Species Of Salamanders Of The Genus Pseudoeurycea (Amphibia: Plethodontidae) From Oaxaca, Mexico, Eduardo A. Aguilar-Herrera, Salomón Sanabria-Urbán, Dulce L. Flores-Martínez, José David Gómez-Tapia, Misael Seba-Chacha, Leopoldo D. Vázquez-Reyes, Francisco A. Rivera-Ortíz, Patricia Ramírez-Bastida, Bruno Cortés-Ortiz, R. Alejandro Calzada-Arciniega, Etienne U. Avila-Ortega, Dónovan I. Víquez-Vega, Omar Hernández-Ordoñez, Christopher Blair, Víctor H. Jiménez-Arcos

Publications and Research

We describe three new species of lungless salamanders (Plethodontidae) in the genus Pseudoeurycea from Cerro Rabon, located on the eastern slopes of the Sierra Mazateca, Oaxaca, Mexico. This mid-elevation mountain, largely surrounded by warmer lowlands, remains relatively understudied. We present molecular and morphological evidence distinguishing the three new species from their congeners. According to our phylogenetic analysis, one of the new species belongs to the P. leprosa group, while the other two are members of the P. juarezi group. Notably, one of the new species represents the fourth worm salamander known from west of the Isthmus of Tehuantepec, and another …


Ancient Wisdom & Its Cultural Relevance: Reimagining Deeper Learning In Science Classrooms Through The Lens Of Yoga And Vedānta, Raaghav Pandya Jan 2026

Ancient Wisdom & Its Cultural Relevance: Reimagining Deeper Learning In Science Classrooms Through The Lens Of Yoga And Vedānta, Raaghav Pandya

Publications and Research

Contemporary calls to reconceptualize how science is taught and understood have brought deeper learning to the forefront of education at-large for its emphasis on critical perspectives, creativity, and student-centered inquiry. Yet this paper argues that its prevailing framework remains constrained by Cartesian dualism, a materialist foundation that disassociates the individual from self, other, and nature, and falls short of addressing the mental health, environmental, and cultural challenges facing youth today. To address this limitation, this paper proposes a complementary convergence between deeper learning and the contemplative traditions of Yoga and Vedānta, whose ancient paradigms of self-inquiry, interconnectedness, and well-being offer …


What Race Means For Health Among Black Americans: How Microaggressions Shape Self-Efficacy And Readiness For Behavior Change, Amanda Lee Almond Jan 2026

What Race Means For Health Among Black Americans: How Microaggressions Shape Self-Efficacy And Readiness For Behavior Change, Amanda Lee Almond

Publications and Research

Objectives: Persistent racial disparities in cardiovascular health among Black Americans reflect not only structural inequities in the United States, but also the racialized meanings of cardiovascular disease reproduced through public and private health communication. Drawing on ecological systems theory, this research examines how beliefs linking race and cardiovascular disease are reinforced through routine clinical interactions and how these meanings shape health behavior change. Method: Across two experimental mixed-methods studies, a model integrating ecological, social–cognitive, and behavior change frameworks was tested. In Study 1 (N = 374), health-message framing was experimentally manipulated to examine effects on self-efficacy and decisional balance while …


Critical Success Factors For An Effective Security Risk Management Program: An Exploratory Case Study, Jason A. Williams, Humayun Zafar, Saurabh Gupta Jan 2026

Critical Success Factors For An Effective Security Risk Management Program: An Exploratory Case Study, Jason A. Williams, Humayun Zafar, Saurabh Gupta

Faculty Articles

This paper evaluates the perceived effectiveness of the security risk management (SRM) programs at a Fortune 500 firm. Layers of management and staff participated in the study. Perceived effectiveness of their SRM programs was based on nine critical success factors (CSFs). Interviews confirmed six initial CSFs (Executive Management Support, Organizational Maturity, Open Communication, Risk Management Stakeholders, Team Member Empowerment, and Holistic View of an Organization) that were extracted from the literature. They were confirmed and synthesized with three additional CSFs (Security Maintenance, Corporate Security Strategy, and Human Resource Development). Implications for SRM are discussed.


Affirmatively Misled: The Commutation Instruction That Distorted Louisiana’S Death Penalty, G. Ben Cohen Jan 2026

Affirmatively Misled: The Commutation Instruction That Distorted Louisiana’S Death Penalty, G. Ben Cohen

Akron Law Faculty Publications

In 1997, Louisiana voters amended the state constitution to mandate that capital juries be instructed on the governor’s power to commute life and death sentences. This amendment, urged by the Louisiana District Attorneys Association, followed a Louisiana Supreme Court ruling that found an earlier clemency instruction violated the state constitution.     The instruction was fundamentally false. Louisiana governors, it turns out, lacked the unilateral authority to commute sentences; such actions require a favorable vote from the Parole Board. This reality became starkly clear in 2023, when the clemency petitions of fifty-six condemned prisoners—many sentenced by juries affirmatively given this instruction—were terminated …


Just Prosecution, G. Ben Cohen Jan 2026

Just Prosecution, G. Ben Cohen

Akron Law Faculty Publications

Prosecutors were once envisioned as the heroes of the criminal legal system, wielding immense power to secure justice. Yet their role remained largely untethered to a coherent, principled framework. Without clear guardrails, traditional prosecution contributed to mass incarceration, racial disparities, and punitive excesses. Progressive prosecution sought to redress these deficiencies, but a lack of cohesive theoretical grounding, accompanied by a divestiture of power, left prosecutions weak. Reform was fragmented by electoral pressures but remained subject to abolitionist critiques. This article asks readers to consider the idea of Just Prosecution as a way of reimagining the prosecutor’s role—raising the question of …


Professional Quality Of Life Among Medical Surgical And Telemetry Registered Nurses, William Lim, Emy-Lee Marie Anglo Ricafrente, Jenny Carrillo Jan 2026

Professional Quality Of Life Among Medical Surgical And Telemetry Registered Nurses, William Lim, Emy-Lee Marie Anglo Ricafrente, Jenny Carrillo

Publications 2026-present

No abstract provided.


06.01.03. Chuck-Wills-Widow, Antrostomus Carolinensis, A. W. Kratter, Ann Hodgson, Florida Ornithological Society Jan 2026

06.01.03. Chuck-Wills-Widow, Antrostomus Carolinensis, A. W. Kratter, Ann Hodgson, Florida Ornithological Society

06.01. <i>Caprimulgidae</i> - Nightjars and Allies

One of the joys of a night walk in spring in the quieter wooded regions of Florida is the great likelihood that you will hear a Chuck-wills-widow singing.


06.01.02. Antillean Nighthawk, Chordeiles Gundlachii, M. Davis, Ann Hodgson, Florida Ornithological Society Jan 2026

06.01.02. Antillean Nighthawk, Chordeiles Gundlachii, M. Davis, Ann Hodgson, Florida Ornithological Society

06.01. <i>Caprimulgidae</i> - Nightjars and Allies

The Antillean Nighthawk is a widespread summer resident across the Greater Antilles and is rare but regular in the Florida Keys and extreme southern Florida mainland.


06.01.01. Common Nighthawk, Chordeiles Minor, R. R. Goodwin, Ann Hodgson, Florida Ornithological Society Jan 2026

06.01.01. Common Nighthawk, Chordeiles Minor, R. R. Goodwin, Ann Hodgson, Florida Ornithological Society

06.01. <i>Caprimulgidae</i> - Nightjars and Allies

The Common Nighthawk is a widespread species found during the breeding season throughout most of the United States and Canada south of the tundra as well as the mountains of central Mexico.


Activist Judicial Restraints, Michael Gentithes Jan 2026

Activist Judicial Restraints, Michael Gentithes

Akron Law Faculty Publications

For decades, jurists and scholars have touted the virtues of judicial restraint—a characteristic of judges who only adjudicate issues they are competent to resolve, thereby avoiding political thickets and preserving their authority. Judicial restraint is ingrained in justiciability doctrines that emanate from Article III of the Constitution. When applied evenhandedly, standing requirements, the political question doctrine, and prudential manageability prerequisites to litigation help the Court maintain an appropriately restrained docket.

The Roberts Court falls well short of this restrained ideal in potentially dangerous and destructive ways. The Court has changed justiciability doctrines into “activist judicial restraints” that, rather than avoiding …


The Inward Gaze: Byung-Chul Han's Achievement-Subjectivity In David Foster Wallace's Short Fiction, Ivan Marquez Jan 2026

The Inward Gaze: Byung-Chul Han's Achievement-Subjectivity In David Foster Wallace's Short Fiction, Ivan Marquez

All Student Theses and Dissertations

David Foster Wallace stated that the aim of his fiction and art was to reflect what it meant to be alive and form a relationship with the reader. In "E Unibus Plurum", Wallace posited that the tenets of Post-Modern fiction were once used to criticize the hypocrisies of the 1950's and 60's American had been subsumed by television and were no longer effective tools of criticism. Wallace argues for a move away from irony and stunt pilotry of postmodern fiction towards a fiction which espoused "single entendre values" (Wallace 192). While Wallace advocated for a return to more traditional story-telling, …


How Do African American Alumni At Private Predominantly White Institutions Describe And Interpret The Influence Of Culturally Responsive Support Spaces On Their Sense Of Belonging, Academic Persistence, And Long-Term Professional Development With The Institutional Context, Karen Williams-Blackman Jan 2026

How Do African American Alumni At Private Predominantly White Institutions Describe And Interpret The Influence Of Culturally Responsive Support Spaces On Their Sense Of Belonging, Academic Persistence, And Long-Term Professional Development With The Institutional Context, Karen Williams-Blackman

All Student Theses and Dissertations

This qualitative case study examined how African American alumni at a private, predominantly White institution (PWI) in the Midwest described and interpreted the influence of culturally responsive support spaces on their sense of belonging, academic persistence, and long-term professional development. Culturally responsive support spaces are defined as environments that affirm identity, provide protection, and foster community, offering relational and cultural validation beyond traditional institutional diversity or compliance-based initiatives. Guided by Critical Race Theory (CRT) and Validation Theory (VT), this research examined how alumni interpreted their interactions with these support spaces and how such experiences influenced their academic trajectories and enduring …


Linking Social Entrepreneurship To Crime Reduction Among Young African Americans In Chicago’S South And West Sides, Grady C. Wheaton Jr. Jan 2026

Linking Social Entrepreneurship To Crime Reduction Among Young African Americans In Chicago’S South And West Sides, Grady C. Wheaton Jr.

All Student Theses and Dissertations

This study examined community members’ perceptions of social entrepreneurship as an employment-centered strategy for addressing youth violence among African Americans on Chicago’s South and West Sides. The study was guided by the following research question: Can social entrepreneurship be leveraged to reduce youth violence among African Americans on Chicago’s South and West Sides, as perceived by community members? Using Fillmore Laundry, a healthcare linen-processing social enterprise located in North Lawndale, as a case example, this quantitative, cross-sectional study collected survey data from 99 eligible community members recruited through community-based partnerships. The survey assessed perceived youth- and community-level program benefits, evaluations …


Exploring Management Strategies To Reduce Workplace Violence: Perceptions Of Illinois Healthcare Professionals, Mary Mack Jan 2026

Exploring Management Strategies To Reduce Workplace Violence: Perceptions Of Illinois Healthcare Professionals, Mary Mack

All Student Theses and Dissertations

This qualitative study examined how managers of nonprofit healthcare facilities in the Chicago metropolitan area implement strategies to reduce workplace violence, what these strategies are and how they are carried out, and what organizational factors facilitate or impede their implementation. Semi-structured interviews were conducted with seven healthcare professionals in management or safety-oriented roles across seven facilities, purposefully sampled through the researcher's professional network. Findings revealed four recurring patterns across the sample. Prevention infrastructure was installed reactively, following specific triggering incidents rather than anticipating documented risk. Facilities consistently favored lower-cost mitigation measures over more resource-intensive prevention strategies. Reliance on short-tenure contract …


Unseen Motherhood, Kylie Zieminski Jan 2026

Unseen Motherhood, Kylie Zieminski

All Student Theses and Dissertations

Unseen Motherhood is a series of photographs that shows what first-time motherhood is really like, starting with pregnancy and going through birth and everything after. I did not want to just show the happy or perfect moments. I wanted to capture the hard parts, the big feelings, and how much a person's identity can change.

There are eighteen black-and-white photographs in this series, all showing my twin sister as she goes through becoming a mother. These images follow her before, during, and after birth. I wanted to show that motherhood is more than just one happy photograph.

I based this …


The Lived Experiences Of Counselors Working With Adults Suffering From Major Depression In Nursing Home Facilities. A Qualitative Phenomenological Study Grounded In A Wellness Perspective, Melissa Arguelles De Jesus Jan 2026

The Lived Experiences Of Counselors Working With Adults Suffering From Major Depression In Nursing Home Facilities. A Qualitative Phenomenological Study Grounded In A Wellness Perspective, Melissa Arguelles De Jesus

All Student Theses and Dissertations

There is new knowledge that major depression disorder (MDD), specifically, is one of the most encountered mental health diagnoses assigned among older adult residents who live in a nursing home (NH) setting (Matos Queiros et al., 2021). Antidepressants are known to be the main improvement factor and optimal management for treating depression; however, consideration for other treatment modalities continues to be explored (Voineskos et al., 2020). Wellness counseling, which is known to foster a person-centered approach, may help NH residents develop coping skills to enhance both overall welfare and everyday functioning across multiple domains. Residents can be empowered as decision …


Binding The Visual Experience Of Law, Nicholas Mignanelli Jan 2026

Binding The Visual Experience Of Law, Nicholas Mignanelli

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Courts Of Indian Offenses, Courts Of Indian Resistance, Alexandra Fay Jan 2026

Courts Of Indian Offenses, Courts Of Indian Resistance, Alexandra Fay

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Psychometric Properties Of A Novel Affective Bias Task And Its Application In Clinical And Nonclinical Populations, Prathik Kalva, Kourtney Kanja, Brian A Metzger, Xiaoxu Fan, Brian Cui, Bailey Pascuzzi, John Magnotti, Madaline Mocchi, Raissa Mathura, Kelly R Bijanki Jan 2026

Psychometric Properties Of A Novel Affective Bias Task And Its Application In Clinical And Nonclinical Populations, Prathik Kalva, Kourtney Kanja, Brian A Metzger, Xiaoxu Fan, Brian Cui, Bailey Pascuzzi, John Magnotti, Madaline Mocchi, Raissa Mathura, Kelly R Bijanki

Faculty, Staff and Students Publications

To mitigate limitations in self-reported mood assessments, we introduce a novel affective bias task (ABT). The task quantifies instantaneous emotional state by leveraging the phenomenon of affective bias, in which people interpret external emotional stimuli in a manner consistent with their current emotional state. This study establishes task stability in measuring and tracking depressive symptoms in clinical and non-clinical populations. Initial assessment in a large non-clinical sample established normative ratings. Depressive symptoms were tracked relative to task performance in a non-clinical sample, as well as in a clinical cohort undergoing surgical evaluation for severe epilepsy. In both cohorts, a stronger …


Lessons Learned From An Epic Transformation Of A Radiation Oncology Department In Guatemala: Keys To Success, Edgar Ruiz, Hiram A Gay, Milton Ixquiac, Angel Velarde, Baozhou Sun, Jose García-Ramirez, Eric Laugeman, Benjamin Li, Jeff Michalski, Vicky De Falla, Geoff Hugo, Jacaranda Van Rheenen Jan 2026

Lessons Learned From An Epic Transformation Of A Radiation Oncology Department In Guatemala: Keys To Success, Edgar Ruiz, Hiram A Gay, Milton Ixquiac, Angel Velarde, Baozhou Sun, Jose García-Ramirez, Eric Laugeman, Benjamin Li, Jeff Michalski, Vicky De Falla, Geoff Hugo, Jacaranda Van Rheenen

Faculty, Staff and Students Publications

Purpose: We describe the radical modernization of a radiation oncology department in a developing country, Guatemala, from 2015 to the beginning of 2024. The Instituto de Cancerología y Hospital Dr. Bernardo del Valle S (INCAN) is the only public radiotherapy clinic serving patient referrals from the Ministry of Public Health and Social Assistance program.

Methods and materials: We describe the state of the radiation oncology department in 2015 versus 2024 while chronicling its gradual transformation. This multifaceted collaboration involved academic centers, government agencies, International Atomic Energy Agency (IAEA), industry, and nonprofits and continues to this day. We analyze the infrastructure, …


Tau In Alzheimer’S Disease: Shaping The Future Patient Journey, Catherine J Mummery, Christopher Chen Li-Hsian, Cristian A Lasagna-Reeves, Rik Ossenkoppele, Christopher C Rowe, Douglas W Scharre, Huali Wang, Simon Kyaga, Jeffrey L Cummings Jan 2026

Tau In Alzheimer’S Disease: Shaping The Future Patient Journey, Catherine J Mummery, Christopher Chen Li-Hsian, Cristian A Lasagna-Reeves, Rik Ossenkoppele, Christopher C Rowe, Douglas W Scharre, Huali Wang, Simon Kyaga, Jeffrey L Cummings

Faculty, Staff and Students Publications

Alzheimer's disease is a complex and multifactorial disease characterized by two key pathological hallmarks: amyloid-beta plaques and tau neurofibrillary tangles. Recent progress has led to the development and approval of disease-targeted therapies for Alzheimer's disease in the form of anti-amyloid-beta monoclonal antibodies. However, findings suggest that amelioration of multiple pathological drivers may be required to maximize clinical effect. An increasing body of evidence suggests that tau is a critical player in Alzheimer's disease pathophysiology, contributing significantly to neurodegeneration and cognitive decline. There are now several tau-targeting drugs in clinical development. In this review, we build on research and advancements in …


Unraveling Posttranslational Modification Complexity: Advances In Quantitative Histone Proteoform Mass Spectrometry, Karl F Poncha, Alyssa T Paparella, Nicolas L Young Jan 2026

Unraveling Posttranslational Modification Complexity: Advances In Quantitative Histone Proteoform Mass Spectrometry, Karl F Poncha, Alyssa T Paparella, Nicolas L Young

Faculty, Staff and Students Publications

Histone proteins and their posttranslational modifications are central to chromatin structure and function. These modifications often occur in combinations, generating a diverse array of histone proteoforms that contribute to the dynamic regulation of chromatin architecture. Advancements in mass spectrometry-based proteomics, particularly top-down and middle-down approaches, have significantly enhanced our ability to characterize these proteoforms and elucidate PTM crosstalk. This review provides an analysis of the epigenetic machinery involved in the addition, recognition, and removal of histone PTMs, emphasizing the complexity introduced by histone variants and combinatorial PTM patterns. We examine the challenges and limitations of traditional antibody-based methods for PTM …


Clinical Factors And Diagnoses Associated With Inappropriate Urine Culture Ordering In Primary Care, Marissa Valentine-King, Barbara W Trautner, Michael A Hansen, Roger Zoorob, Lisa C K Danek, Kenneth Muldrew, Forrest Hudson, Robert L Atmar, Larissa Grigoryan Jan 2026

Clinical Factors And Diagnoses Associated With Inappropriate Urine Culture Ordering In Primary Care, Marissa Valentine-King, Barbara W Trautner, Michael A Hansen, Roger Zoorob, Lisa C K Danek, Kenneth Muldrew, Forrest Hudson, Robert L Atmar, Larissa Grigoryan

Faculty, Staff and Students Publications

Objective: Evaluate the prevalence and risk factors for inappropriately ordered urine cultures in primary care.

Design: Cross-sectional study using chart reviews.

Setting: Two primary care, safety-net clinics in Houston, Texas.

Patients: Non-pregnant adults without a urinary catheter who had a urine culture and a primary care visit between 11/2018 and 3/2020.

Methods: We classified patients lacking physician documentation of the following symptoms as having an inappropriately ordered urine culture: dysuria, frequency, urgency, hematuria, fever, chills, costovertebral angle tenderness, nephrolithiasis, and pain (suprapubic, pelvic, or flank). We extracted patient demographics, visit-related diagnostic codes, past medical history, and urine culture results. Diagnostic …


In Vivo Volumetric Visualization And Quantification Of Cumulus Expansion In Mice With Intravital Optical Coherence Tomography, Kohei Umezu, Frank J Brooks, Irina Larina Jan 2026

In Vivo Volumetric Visualization And Quantification Of Cumulus Expansion In Mice With Intravital Optical Coherence Tomography, Kohei Umezu, Frank J Brooks, Irina Larina

Faculty, Staff and Students Publications

Ovulation is preceded by a critical physiological process known as cumulus expansion, during which the cumulus cell layer surrounding the oocyte undergoes structural remodeling. Despite the recognized importance of this process for reproductive success, live quantitative imaging of cumulus expansion has not been previously achieved due to limitations of current imaging technologies for deeply located ovaries. In this study, we employed intravital optical coherence tomography for three-dimensional visualization of mouse follicles containing cumulus-oocyte complexes (COC) within the physiological context of the ovary, both ex vivo and in vivo. This method enabled time-lapse measurement of cumulus layer thickness and COC …


Evolving Burden Of Metabolic Dysfunction-Associated Steatotic Liver Disease And Its Complications In A Us Nationwide Healthcare System, Basim Ali, Ronald Samuel, Jennifer R Kramer, Liang Li, Xian Yu, Yumei Cao, Roxanne Desiderio, George Cholankeril, Steven M Asch, Hashem B El-Serag, Fasiha Kanwal Jan 2026

Evolving Burden Of Metabolic Dysfunction-Associated Steatotic Liver Disease And Its Complications In A Us Nationwide Healthcare System, Basim Ali, Ronald Samuel, Jennifer R Kramer, Liang Li, Xian Yu, Yumei Cao, Roxanne Desiderio, George Cholankeril, Steven M Asch, Hashem B El-Serag, Fasiha Kanwal

Faculty, Staff and Students Publications

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health problem. Measuring the burden of cirrhosis and its complications in people with MASLD is important to inform health care delivery.

Methods: We aimed to quantify the changes in the burden of MASLD-related cirrhosis and hepatocellular carcinoma (HCC) in a nationwide U.S. healthcare system. We used data from the Veterans Health Administration to examine temporal trends between 2010 and 2021 in the annual incidence and prevalence of cirrhosis and HCC in a large cohort of patients with MASLD, and to compare them to those in patients with hepatitis C …


Platelet Extravasation In The Microvasculature: An Under-Appreciated Role For Platelets, Justin A Courson, Vahid Afshar-Kharghan, Alan R Burns, Rolando E Rumbaut Jan 2026

Platelet Extravasation In The Microvasculature: An Under-Appreciated Role For Platelets, Justin A Courson, Vahid Afshar-Kharghan, Alan R Burns, Rolando E Rumbaut

Faculty, Staff and Students Publications

In recent years, evidence has accumulated highlighting the presence and role of platelet extravasation - wherein platelets accumulate in tissue parenchyma - at a variety of sites throughout the body. While platelets are traditionally known for their roles in hemostasis and thrombosis, it is evident that platelets are potent mediators of inflammation across an array of physiological and pathological contexts. While anucleate and small in size, platelets contain a rich diversity of molecules in their granules capable of modulating cell proliferation, tissue repair, and a host of immune responses. There is growing evidence that platelet extravasation out of the vascular …