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Fgf19 As A Colorectal Cancer Serum Biomarker And Fgfr4 As A Mediator Of Anti-Her2 Resistance In Breast Cancer, Jordan Beardsley

Graduate Studies Theses and Dissertations 2026

The fibroblast growth factor 19 (FGF19)-fibroblast growth factor receptor 4 (FGFR4) signaling pathway regulates hepatic metabolism, bile acid (BA) synthesis, and hepatocyte proliferation. This signaling axis also is implicated in promoting tumor progression, therapeutic resistance, and metastasis in certain cancers.

In colorectal cancer (CRC) there is a critical need for non-invasive biomarkers for disease detection and monitoring. We identified FGF19 as a candidate CRC serum marker through meta-transcriptomics and found FGF19 to be expressed and secreted by CRC cell lines. Tumor-derived FGF19 was detectable in mouse serum at levels correlating with tumor volume in a subcutaneous xenograft model. RNA sequencing …

Non-Destructive Hhxrf Archaeometry For Grouping Individuals Via Trace Element Analysis Of Dental Remains, Griffon G. Binkowski

Graduate Studies Theses and Dissertations 2026

Handheld X-ray fluorescence (HHXRF) spectrometry has been validated as an accurate, non-destructive method for analyzing archaeological osseous materials. This study utilizes HHXRF to address key bioarchaeological questions, including population differentiation, individuation, and the interpretation of bioaccumulated trace elements versus diagenetic impacts. Using dental enamel from the Maya site of Altun Ha, Belize (n=20) and several Roman-Christian sites in the Dakhleh Oasis in Egypt (n=6), the occlusal surface of molar crowns was assayed in air using a Bruker Tracer III- equipped with a 12 mil Al, 1 mil Ti, 6 mil Cu filter. Semi-quantitative trace element ratios (Sr/Ca, Fe/Ca, and Zn/Ca) …

An Examination Of The Impact Of School Context And Socioeconomic Status On Agency And Creative Productivity In Gifted High School Students, Elizabeth Bronson

Graduate Studies Theses and Dissertations 2026

This explanatory sequential mixed methods study investigated gifted high school students’ perception of the agency afforded them within school settings, and the relationship between these perceptions and their creative productivity. A sample of 140 students was drawn from a population of 966 identified gifted high school students. These students were contacted via their parents and asked to complete the Agentic Engagement Scale (AES) questionnaire which provided gifted high school students’ perceptions of the agency afforded at school. No significant differences in perceived agency were found across demographic variables, including socioeconomic status and school type. Of the respondents, 10 students were …

A Systematic Review And Characterization Of Privacy Noncompliance In Real-World Applications, Alexander E. Charkiewicz

Graduate Studies Theses and Dissertations 2026

Software applications increasingly rely on user data to provide their functionality, but improper handling of such data can lead to serious privacy noncompliance with applicable regulations and policies. A prominent example is the Facebook–Cambridge Analytica scandal, in which a third-party application collected the personal data of approximately 87 million Facebook users without users' consent. Despite growing attention to privacy compliance, two key challenges hinder the systematic understanding and analysis of privacy noncompliance. First, unlike security vulnerabilities, which have been systematically categorized through taxonomies such as the Common Weakness Enumeration (CWE), privacy noncompliance lacks a technical taxonomy describing how it manifests …

Vaccine Hesitancy In Arabic Discourse: A Multi-Method Social Media Study, Nada Dimashkieh Chehab

Graduate Studies Theses and Dissertations 2026

Vaccine hesitancy — the state of uncertainty about vaccination — poses global public health challenges, undermining efforts to prevent infectious diseases. It is also a contextual phenomenon, shaped by social and political forces. While survey-based research on vaccine hesitancy is abundant both globally and in the Arab world, humanities-oriented approaches using discourse analysis remain limited especially in Arabic on social media: some have tracked trends on Twitter, but virtually none have done so on Facebook. This dissertation addresses these gaps through a multimethod design combining Textual and Trend Analyses and Critical Discourse Study. It examines vaccine-related trends and discourses among …

Design, Fabrication Modeling, And Optical Metrology Of Mwir Silicon Metalenses, Weiyu Chen

Graduate Studies Theses and Dissertations 2026

Mid-wave infrared (MWIR) optical systems require compact, broadband, manufacturable components whose performance can be predicted and measured reliably. Silicon metalenses are attractive because silicon combines high refractive index, MWIR transparency, and semiconductor-compatible fabrication. This dissertation develops a scale-bridging design–fabrication-modeling–metrology framework for MWIR silicon metalenses.

A shared full-aperture framework connects meta-atom libraries, physical layout generation, angular-spectrum propagation, point-spread-function calculation, and focal-plane energy metrics. Building on this foundation, the Dispersive Sweatt Model (DSM) incorporates meta-atom dispersion into conventional ray-tracing software, enabling broadband co-optimization of metasurfaces and refractive elements. A process-aware design framework then incorporates scanning electron microscopy (SEM)-measured height–radius relationships produced by …

An Exploration Of The Professionalization Of Graduate Students Using Rhetorical Theory, Jennifer M. Crowell

Graduate Studies Theses and Dissertations 2026

This qualitative study examines the professionalization of graduate students as a rhetorically mediated and relational process of identity development within an interdisciplinary doctoral program. While existing scholarship emphasizes institutional structures and formal mechanisms of professional preparation, less attention has been given to how graduate students experience professionalization at the individual level. This study addresses that gap by exploring how students interpret expectations, use rhetorical strategies, and construct professional identities across multiple disciplinary contexts.

Grounded in organizational rhetoric and community of practice theory, the study investigates how graduate students in the Texts & Technology Ph.D. Program at the University of Central …

An Empirical Comparison Of K-Nearest-Neighbors And Logistic Regression Classification Models, Jackson Cushing

Graduate Studies Theses and Dissertations 2026

This thesis presents an empirical comparison of two classification methods: Logistic Regression and K Nearest Neighbors (KNN). The primary objective of this research is to evaluate the strengths and limitations of each method when applied to real-world datasets. Several publicly available datasets on diabetes, breast cancer, heart attack risk, and cardiovascular disease, were analyzed. For each dataset, K Nearest Neighbors models were implemented in the same way logistic regression had already been applied. The results demonstrate that while logistic regression offers interpretable parameter estimates and performs well when the underlying predictor and outcome relationship is approximately linear, however KNN can …

Non-Gaussian Phenomena In Light Scattering And Applications, Shubham Atul Dawda

Graduate Studies Theses and Dissertations 2026

Physical reality is rarely deterministic; which, when probed by electromagnetic fields that also fluctuate, leads to observables that are most efficiently modelled as statistical processes. At equilibrium, this is usually achieved by invoking the Gaussian statistics of underlying physical processes, however, in practice, one often encounters out-of-equilibrium conditions where Gaussian descriptions may not suffice. Such situations are plentiful in nature– from biology to astronomy. This dissertation addresses several non-Gaussian phenomena associated with light scattering, and includes specific models’ derivations, experimental techniques developments, and demonstrations of potential applications. The systematic presentation will consider circumstances that infringe upon specific assumptions of the …

Independent And Interacting Effects Of Co-Presence And Social Media 'Likes' On Online Disinhibition, Margaret M. Doheny

Graduate Studies Theses and Dissertations 2026

Social media platforms have fundamentally transformed interpersonal communication by creating environments in which behaviors are publicly reinforced through visible social feedback systems such as “likes.” Although prior research has linked online environments with increased disinhibition and negative behavior, existing literature has primarily focused on anonymity and invisibility as the primary mechanisms underlying these effects. However, the mechanistic role of physical and psychological co-presence in driving online disinhibition has received little empirical investigation. The central aim of the present study was to determine whether reduced social presence and the selective reinforcement of negative content contribute to online disinhibition and anticipatory reward-seeking …

Exploring The Experiences Of Late Age-On-Arrival Multilingual Learners In Postsecondary Education, Robyn D. Ecklund

Graduate Studies Theses and Dissertations 2026

Multilingual learners (MLs) are the fastest growing population in the United States public school system (Biondi et al., 2024; Kanno & Cromley, 2013; Perez & Morrison, 2016; Varghese & Fuentes, 2020). Within this population of students, there is a subset of students that arrive in the United States during secondary school. These “late age-on-arrival” students face significant linguistic, cultural and social challenges in their pursuit of postsecondary success after high school (Kanno, 2021; Kanno & Cromley, 2013; Perez & Morrison, 2016). This interpretative phenomenological analysis sought to answer the research question: what are the lived experiences of late age-on-arrival MLs …

Detecting Error In Ai-Generated Text: The Effects Of Authorship And Word Presentation Speed, Gabriela Flores Cruz

Graduate Studies Theses and Dissertations 2026

The increased us of artificial intelligent (AI) chatbots powered by Generative Pre-trained Transformers has raised concerns about users’ ability to detect errors of AI-generated text. This dissertation examined how readers identify inconsistencies in AI-generated expository passages using the inconsistency detection paradigm from comprehension monitoring research. Across two experiments, it investigated whether perceived authorship and word presentation speed influenced inconsistency detection. Experiment 1 used a 3 (author: human, AI, no author) × 2 (inconsistency type: internal, external) between-subjects design. Perceived authorship did not significantly affect hit rates, sensitivity, or response bias. Exploratory analyses indicated that reading comprehension and working memory predicted …

Gaining Voice, Creating Opportunity: An Exploration Of Non-Native English-Speaking Students’ Sources Of Self-Efficacy In U.S. College Public Speaking Classrooms, Desiree M M Flores-Molina

Graduate Studies Theses and Dissertations 2026

This qualitative dissertation explores the sources of public speaking self-efficacy among non-native English-speaking international students enrolled in U.S. college public speaking courses. The study applies Bandura's social cognitive theory to examine how students describe the experiences that shape their confidence and perceived ability to succeed, with attention to mastery experiences, vicarious experiences, verbal persuasion, and physiological and affective states. It also considers how classroom practices and instructor support contribute to or constrain students' confidence.

Data were collected through semi-structured student interviews, guided reflection artifacts connected to major speech assignments, and key-informant interviews with public speaking instructors. Thematic analysis was used …

Investigating The Impact Of School Leaders’ Leadership Style And Teachers’ Intrinsic Motivation For Improved Science Instruction In Elementary Schools, Leila M. Greene

Graduate Studies Theses and Dissertations 2026

A report by the National Academies of Sciences, Engineering, and Medicine, determined that 69% of U.S. elementary teachers are not prepared to teach science, especially in the areas of earth/space and physical sciences. As a result, some elementary teachers avoid teaching science. School administrators play a key role in providing a supportive environment to inspire and motivate elementary science teachers. For this reason, the study utilized the Self-Determination Theory (SDT), to examine three types of school leadership styles (Transformational, Transactional, and Laissez-Faire) and how they impact the intrinsic motivation for elementary science teachers in three areas including autonomy, competency, and …

Policy Into Practice: Exploring School Counselors' And School Psychologists' Knowledge And Sensemaking Towards The Application Of Alternative Gifted Identification Criteria For Lower Socioeconomic Students, Brittany E. Hague

Graduate Studies Theses and Dissertations 2026

Persistent underrepresentation of students from lower socioeconomic status (SES) backgrounds in Gifted education reflects long-standing structural inequities embedded in identification policies and practices. In response, many Florida school districts have adopted equity-oriented identification reforms, including universal screening, local norms, and multiple-measure approaches. However, policy equity does not automatically translate into equitable outcomes; rather, it is mediated through the interpretive work of school-based practitioners. Guided by Sensemaking Theory, this convergent mixed-methods study examines how school counselors and school psychologists construct meaning around alternative Gifted identification criteria and how their beliefs, professional judgment, and organizational contexts shape implementation. The study explores how …

Examining Teachers’ Data Usage Using The Teacher Data Use Survey, Natasha L. Hawkins

Graduate Studies Theses and Dissertations 2026

The United States spends approximately 2.7 billion dollars on classroom assessments and local exams for K-12 students (SIMBA, 2019).  However, despite this financial investment and the adoption of data-driven frameworks such as Multi-Tiered System of Support, the U.S. Department of Education found that only 55% of teachers used student data to make instructional decisions (U.S. Department of Education, 2007).  This study aims to explore the psychological and organizational factors that influence teachers’ data use when making instructional decisions.

This study used the Teacher Data Use Survey (TDUS) to investigate the extent that teachers’ use of data could be predicted by …

Strategic Signaling Or Structural Friction?: How Ai Disclosure Moderates Resource-Performance Dynamics In Hotels And Restaurants, Jaewan Heo

Graduate Studies Theses and Dissertations 2026

Artificial intelligence (AI) has become an increasingly important strategic issue in the hospitality industry. While prior research has primarily examined AI as an operational technology that improves efficiency and service delivery, less attention has been paid to how AI-related disclosures influence investor evaluations of firm resources. This dissertation investigates whether AI-related disclosures moderate the relationship between organizational resources and financial performance in publicly traded hospitality firms.

Drawing on signaling theory and the resource-based view, this study conceptualizes AI disclosures as strategic signals that shape investor perceptions of firm capabilities and future value creation. Firm-level financial data were obtained from Compustat …

Ex Vivo Sensitivity Assays With Molecular Validation To Guide Preclinical Drug Selection For Schwann Cell Tumors, Ethan W. Hass

Graduate Studies Theses and Dissertations 2026

Schwann cells are the glial cell of the peripheral nervous system. They are dependent on receptor tyrosine kinase-mediated RAS signaling, cell matrix adhesion, and cell-cell contact to proliferate during nerve development and repair. These pathways become deregulated with loss of function of the merlin tumor suppressor encoded by NF2, leading to benign tumors called schwannomas. Patients with NF2-related schwannomatosis (NF2-SWN) develop bilateral vestibular schwannomas that cause hearing loss, tinnitus, and death from brainstem compression if untreated. Severe NF2-SWN causes multiple spinal and peripheral schwannomas and neuropathic pain. Schwannomas require careful monitoring, trial and error use of repurposed anti-cancer …

Integrated Optical Probes For Confocal Scanning Imaging And Adjustable Coherent-Gated Dynamic Sensing, Yonglin Huang

Graduate Studies Theses and Dissertations 2026

Optics and photonics have been one of the most important sciences and technologies that impact modern human life in a big way. For example, fiber-optics for communications and artificial intelligence. Optical probes are critical components for optical imaging and optical sensing technologies that have been actively researched and developed in the past decades. Advanced fiber-optic sensor probes with smaller size, better performance, lower noise, higher photon efficiency, rapid sensing time, and lower cost are needed in many applications, such as nanoscale material science, chemistry, and biomedical fields, etc.  In this project, new fiber-optic sensor probe technologies and integrated micro-optic devices …

A Case Study Examining Organizational Influences On Student Teacher Placement In K-12 Classrooms, Rachel L. Ickes

Graduate Studies Theses and Dissertations 2026

Student teaching is a prominent and required learning experience in most teacher education programs. The learning that takes place in student teaching blends pedagogy with practice. However, not all student teaching placements provide positive learning experiences for student teachers. This descriptive case study examines the organizational factors that affect the process of student teacher placement at K-12 classroom sites by one teacher education program. For this case study, one teacher education program in the southeastern United States was selected as the case site, and the case for this study is the process of student teacher placement. Semi-structured interviews, observation, and …

Integrated Corridor Management Framework For Severe Freeway Incidents, Sanjida Afroz Iqra

Graduate Studies Theses and Dissertations 2026

Traffic incidents are a major source of non-recurrent congestion on urban freeways, generating substantial mobility, safety, and economic impacts. Severe incidents that block multiple or all travel lanes are particularly disruptive because they degrade freeway operations and propagate congestion onto surrounding arterials. Effective Integrated Corridor Management (ICM) requires the ability to identify severe incidents, estimate their network-wide impacts, and anticipate the traffic conditions and driver behaviors that contribute to instability. This dissertation develops a data-driven ICM framework to address these challenges using real-world incident, crash, detector, and connected vehicle data from major Central Florida corridors, including I-4 and SR-417. The …

Investigating The Anti-Apoptotic Properties Of The N-Terminus Of The Chlamydia Trachomatis Effector Tarp, Kasey S. Jordan

Graduate Studies Theses and Dissertations 2026

As the most prevalent bacterial STI in the United States and leading cause of infection-related blindness worldwide, the obligate intracellular bacteria, Chlamydia trachomatis (Ct), poses a significant threat to public health. As an obligate intracellular bacteria, invasion of the host cell is a crucial step in Chlamydia’s developmental cycle. To drive invasion, Ct injects prepackaged effectors into the host cell using a T3SS. An early Chlamydial effector, translocated actin recruiting phosphoprotein, or Tarp, interacts with host cell actin to promote invasion, mediated via Tarp’s C-terminal region. Although the function of Tarp’s C-terminus is well defined, the Tarp’s N-terminus …

Teledentistry: A Path To Minimize Emergency Department Dependency For Dental Issues, Aishwarya Joshi

Graduate Studies Theses and Dissertations 2026

Teledentistry has been promoted as a strategy to minimize emergency department (ED) visits for non-traumatic dental conditions (NTDCs). However, it remains unclear whether structural readiness or temporary policy expansion drives sustained reductions in reliance on the ED. This study integrates Andersen’s Behavioral Model of Health Services Use and Diffusion of Innovation (DOI) theory to examine determinants of Medicaid NTDC ED utilization and Tele-dentistry adoption.

Andersen’s model posits that utilization is shaped by predisposing, enabling, and need factors, whereas DOI theory emphasizes structural attributes that influence adoption, including relative advantage, compatibility, complexity, trialability, and observability. Combining these frameworks allows for a …

Homoplasy Of Maxillary Orthognathism In Derived Homo, Jared Jordan

Graduate Studies Theses and Dissertations 2026

The evolution of the orthognathic condition in the genus Homo represents a monumental transition toward the facial morphology of modern humans from that of earlier hominins, but the phylogenetic positioning of this transformation remains poorly understood. This study investigated temporal trends in maxillary and mandibular prognathism in the genus Homo, and whether maxillary and mandibular shortening in East Asian H. erectus and later East Asian Middle Pleistocene Homo (e.g., Homo longi) represent independent derivations of orthognathic morphology, thereby making orthognathism a homoplasy in the genus Homo. Using a sample of roughly 109 cranial and mandibular specimens spanning …

The Impact Of Criminal Justice System Contact On Adolescents In The U.S.: Prescription Drug Misuse, Marijuana Use, Health Outcomes, And Demographic Characteristics, Fadime Gokce Karaaslan

Graduate Studies Theses and Dissertations 2026

Criminal justice system (CJS) contact remains a pervasive feature of social life in the United States, with both direct and indirect consequences for adolescents and their families. Although previous research has explored the consequences of direct CJS contact, less is known about how indirect or vicarious contact affects adolescents’ well-being and substance use. Drawing on data from the Future of Families and Child Wellbeing Study (FFCWS), this study investigates the association between parental incarceration and vicarious police stops, defined as police stops involving parents, siblings, friends, neighbors, or other social ties, and adolescent well-being. Findings indicate that CJS contact is …

Sustaining High-Quality Service-Learning In Research Intensive Universities: A Qualitative Study Of Instructor Perspectives, Marika Koch

Graduate Studies Theses and Dissertations 2026

In a world that often feels disconnected due to our sociopolitical climate, there is a need to create socially aware and civically engaged adults. Service-learning integrated into higher education courses can do that and more. Research indicates that both students and the community benefit significantly when students participate in effective service-learning classes. Students who take service-learning courses in college tend to exhibit higher academic achievement, enhanced social and emotional skills, and greater long-term civic engagement. Effective service-learning courses share three common elements: they foster a strong connection to course objectives, promote reciprocity for all involved, and encourage active student reflection. …

Adapting Dramaturgical Pedagogy Into A Practical Framework For Young Dramaturgs, Kirby Lee

Graduate Studies Theses and Dissertations 2026

Dramaturgy, while more established as practice in professional theatre, remains inconsistently applied and often underutilized in university theatre contexts. Despite its historical significance and continued evolution, some theatre companies and many academic institutions still struggle to clearly define or effectively integrate the dramaturg’s role. This thesis hopes to create a framework for novice dramaturgs by examining the origins and development of dramaturgy, analyzing its shifting functions in contemporary theatre, offering my own dramaturgical experiences through the lens of three quite different plays and finally, establishing basic principles of the discipline. Beyond its historical and professional contexts, this study investigates the …

Contextual Influences On Algebra 1 Achievement In Florida: A Multilevel Analysis Of Fsa Data And Policy Implications For B.E.S.T., Alberto Leiro Jr

Graduate Studies Theses and Dissertations 2026

This study examined how school-level and district-level contextual factors are associated with Algebra 1 achievement in Florida using a multilevel modeling framework. Drawing on statewide publicly available data from the Florida Standards Assessments (FSA), the analysis included schools nested within districts to account for the hierarchical structure of educational data. School-level predictors included absenteeism, economic disadvantage, English language learner status, student mobility, and the proportion of students with disabilities, while district-level variables included poverty and crime rates. Results from the null model indicated that a meaningful proportion of variance in Algebra 1 achievement was attributable to differences among districts, supporting …

Bridging The Gap: How Sociodemographic Factors Shape Adults’ Decisions To Pursue Hearing Aids, Logan Lorié

Graduate Studies Theses and Dissertations 2026

Despite hearing aids becoming more accessible to adults with hearing loss, hearing aid uptake rates remain low, partly due to sociodemographic factors that influence an adults’ decision to pursue amplification. This study systematically reviewed research on how sociodemographic factors – to include age, gender, socioeconomic status, education level, race/ethnicity, and military status – contribute to the decision-making process. This review guided an analysis of these variables using the National Health and Nutrition Examination Survey (NHANES), a large public health database. To ensure enough hearing aid users were included in the analysis, NHANES data were combined across survey cycles from 1999 …

High School Teachers' Perceptions And Experiences Of Legislative Changes: An Interpretative Phenomenological Analysis, Marie Lewis

Graduate Studies Theses and Dissertations 2026

The purpose of this interpretative phenomenological analysis was to explore the perceptions and experiences of high school English Language Arts teachers in one public school district in the state of Florida as they navigated educational legislation that has been implemented over the last five years. The study interviewed ten experienced high school ELA teachers who had taught for more than five years in Florida’s public school system. One semi-structured interview was conducted along with brief follow-ups to share thematic statements with the participants. This study also included a document analysis of HB 1467 and HB 1069 as well as the …