Digital Commons Network^™

Pregnancy And Breastfeeding Are Associated With Less Later-Life Cognitive Decline In A Longitudinal, Prospective Cohort, Molly M Fox, Jennifer E Bramen, Dayoon Kwon, Mark A Espeland, Yijia Sun, Li Zhang, Aladdin H Shadyab, Ramon Casanova, Joann E Manson, Marcus Y Chang, Verna R Porter, Leslie V Farland, Qian Xiao, Robert A Wild, Prabha Siddarth, Carolyn J Crandall

Faculty, Staff and Student Publications

Introduction: The brains of female mammals evolved to undergo structural and functional changes during pregnancy and lactation, equipping them for motherhood. However, long-term cognitive health implications of these adaptations in women are poorly understood.

Methods: In the Women's Health Initiative (WHI) Memory Study (WHIMS; n = 7427) and WHI Study of Cognitive Aging (WHISCA; n = 2304), postmenopausal women completed reproductive history interviews, annual global cognitive assessment from mean age 70 for up to 13 years, and multi-domain cognitive testing for up to 8 years.

Results: Each additional month pregnant was associated with higher scores of global cognition. Each additional …

Artificial Light At Night Extends Pollen Season And Elevates Allergen Exposure, Brandt Geist, Lin Meng, Daniel S W Katz, Huidong Li, Franz Hölker, Qian Xiao

Faculty, Staff and Student Publications

Artificial light at night (ALAN), a growing environmental stressor in urban ecosystems, disrupts natural light-dark cycles and alters plant phenological events such as leaf-out and flowering. However, the extent to which ALAN influences airborne pollen season timing and exacerbates allergy-related health risks remains largely understudied. This study investigates how ALAN influences the timing and duration of the airborne pollen season across the Northeastern United States from 2012 to 2023 and the consequences of allergenic pollen exposure. Using daily pollen concentrations from the National Allergy Bureau, ALAN data from the Visible Infrared Imaging Radiometer Suite product, and gridded Daymet climate data, …

Plasma Proteomic Profile Of Dietary Potassium And Incident Ckd, Jiaqi Yang, Lauren Bernard, Jingsha Chen, Valerie K Sullivan, Bing Yu, Eugene P Rhee, Paul A Welling, Casey M Rebholz

Faculty, Staff and Student Publications

Background:: There is a need for objective biomarkers of dietary potassium. The mechanisms through which dietary potassium influences kidney health are incompletely understood.

Methods:: Atherosclerosis Risk in Communities study participants at visit 3 (1993–1995) with dietary and proteomics data were randomly divided into discovery (N=6,814) and replication (N=3,380) sets. We examined associations between dietary potassium and 4,955 aptamers using multivariable linear regression, adjusting for sociodemographic factors, health behaviors, and estimated glomerular filtration rate, with a false discovery rate of 0.05. Then, we tested the prospective associations between potassium-related proteins and incident chronic kidney disease (CKD).

Results:: …

Examining Tobacco Prevention And Cessation Among Dental Students In Southern Italy, Olga Di Fede, Samuel Tundealao, David Okuji, Gaetano La Mantia, Irene Tamí-Maury

Faculty, Staff and Student Publications

Background: Previous studies have reported that tobacco use among healthcare providers (HCPs) has a negative impact on their beliefs and attitudes toward tobacco prevention and control measures. However, little is known about these among Italian dental students. Therefore, this single-site study examined tobacco use behaviors and the knowledge, attitudes, and perceptions of dental students at a public university in Southern Italy regarding tobacco prevention and control.

Methods: A cross-sectional study through an online survey was conducted among 115 students aged 18 + years enrolled in dentistry and dental hygiene programs at a Southern Italy university. Chi-squared, Fisher's, t-tests, and …

Adapting A Smartphone-Based Auricular Point Acupressure Self-Management Program For Rural Chronic Musculoskeletal Pain: Qualitative Study, Jungkyung Min, Peiyin Hung, Jane N Bolin, Rupsikha Bora, Sarah Pace, Patricia Pitones, Hulin Wu, Jennifer Kawi

Faculty, Staff and Student Publications

Background: Chronic musculoskeletal pain is more prevalent in rural areas where access to pain interventions, including complementary approaches like Auricular Point Acupressure (APA), remains limited. APA is a non-invasive, needle-free approach, and its smartphone-based self-management delivery model has not been optimized for rural contexts.

Objectives: To explore the perspectives of rural partners on adapting a smartphone-based Auricular Point Acupressure-Self-Management (APA-SM) program to better meet rural needs. Study objectives were to: (1) refine the APA-SM program for rural adults, (2) identify implementation barriers, (3) understand practice workflows and engagement, and (4) identify strategies to integrate the APA-SM program into rural pain …

The Disability History Of Brown V. Board Of Education, Britney Wilson

Articles & Chapters

In 1952, two years before the Supreme Court of the United States decided Brown v. Board of Education, Black deaf students in Washington, D.C., who had been prohibited from attending the local school for white deaf students and forced to go to school in Maryland, won the right to be educated in their hometowns in Miller v. Board of Education of District of Columbia. Brown is heralded as one of the most important racial justice cases of all time. It overturned Plessy v. Ferguson's longstanding "separate but equal" mandate and ruled that the segregation of students based on race violates …

Data For Forthcoming Article: "Employing Zebrafish To Understand Genetic Drivers Of Epilepsy-Related Comorbid Behaviors", Colleen Carpenter-Swanson

Biology Faculty Publications

Forthcoming from Frontiers in Pharmacology:

"Children with epilepsy frequently experience a range of significant comorbidities beyond seizures, such as motor dysfunction, cognitive impairment, and neurodevelopmental delays. In some cases, these comorbidities contribute more significantly to overall disease burden than the seizures themselves. To improve quality-of-life (QOL) for these children, treatment options should be selected that control seizures and ameliorate comorbidities. Unfortunately, such therapeutics remain largely elusive. Addressing this issue requires suitable preclinical models. Here we used CRISPR-generated zebrafish with single-gene mutations linked to pediatric epilepsy and applied clinically-relevant behavioral assays to study the effects of these mutations. Using high-throughput locomotion-based …

Subgroup Identification Of Disparities In Buprenorphine Discontinuation In Opioid-Use Disorder: A Virtual Twins Machine Learning Approach Using Nationwide United States Claims Data, 2006–2022, Kehe Zhang, Paula A Jaimes-Buitron, Wanru Guo, Yanmin Gong, Yuanxiong Guo, Carolina Vivas Valencia, Cici Bauer

Faculty, Staff and Student Publications

Buprenorphine retention is crucial for effective treatment of opioid use disorder (OUD), yet disparities in treatment discontinuation persist. This study aims to identify and quantify disparities in buprenorphine treatment retention using a machine learning framework adapted from Virtual Twins approach focusing on disparities related to sex, age, insurance type, geographic region, mental health status and community-level Social Vulnerability Index (SVI). Using a nationwide longitudinal cohort, we applied a two-stage machine learning approach. In Stage one, we trained classification models to estimate the counterfactual differences in treatment discontinuation across disparity types. Model performance was assessed using C-statistics and precision-recall curve. In …

Improving Overall Risk Ranking Via Subgroup-Level Information Borrowing In Survival Risk Stratification, Tia S Thomas, Jing Ning, Ruosha Li

Faculty, Staff and Student Publications

Effective risk stratification is essential for providing tailored therapies, improving patient outcomes, and optimizing healthcare resources by identifying sub-populations with similar health risks. However, accurate risk ranking is challenging in the presence of heterogeneous subgroups. Under these instances, subgroup-level information can be leveraged to refine the overall risk ranking. We propose a novel approach that integrates within-subgroup risk ranking percentiles to enhance the overall cohort risk stratification. This method uses both a global model and subgroup-specific models along with optimized weights to improve discriminatory performance across the entire cohort. The proposed method is validated through extensive simulations and applied to …

A Qualitative Examination Of Human Papillomavirus Vaccine Access, Beliefs, And Behaviors Among Adult Males Aged 18–35: Applying The Health Stigma And Discrimination Framework, Jacquelin I Cordero, Louis D Brown, Jesús M Alemán, María E Fernández, Serena A Rodríguez, Eva M Moya

Faculty, Staff and Student Publications

Background: Males, who disproportionately account for 83% of oropharyngeal cancer cases, are underrepresented in health promotion research, including human papillomavirus (HPV) vaccination studies. The initial exclusion of males in HPV vaccine research, policies, and interventions has negatively affected male vaccine uptake. Furthermore, stigma, a well-documented barrier to healthcare engagement, has been overlooked in HPV vaccination behaviors. This study aimed to provide a more contextualized understanding of HPV vaccine disparities among adult males by applying the Health Stigma and Discrimination Framework (HSDF) to examine how stigma is produced, enacted, and sustained across social systems, which may impact male vaccine uptake.

Methods: …

The Longitudinal Effect Of Repetition And Practice On The Accuracy Of Lay Anal Examinations For Detecting Perianal And Anal Canal Abnormalities: A Prospective Study, Alan G Nyitray, Timothy L Mcauliffe, Jenna Nitkowski, Cameron Liebert, Michael D Swartz, Ashish A Deshmukh, Jared Kerman, Ellen Almirol, John A Schneider, J Michael Wilkerson, Lu-Yu Hwang, Derek Smith, Duo Yu, Aniruddha Hazra, Elizabeth Y Chiao

Faculty, Staff and Student Publications

Background: While anal cancer screening is now recommended in several countries for high-incidence populations, barriers impede screening uptake. It is well known that patient recognition of symptoms increases cancer screening uptake, and we previously demonstrated that patients can detect small masses at the perianus and in the anal canal. In this current analysis, we aimed to longitudinally assess the effect of repetition and practice on patient self-recognition of small masses.

Methods: Individuals and couples of sexual minority men and transgender women were taught to conduct an anal self-examination or anal companion examination (ASE/ACE) at visit 1 and then randomized to …

Investigation Of Succinylated Zwitterionic Polyethylenimine/Dna Complexes: Performance In Serum, Internalization, And Intracellular Fate, Levi Lampe

Theses and Dissertations--Chemical and Materials Engineering

Gene therapy has promised to revolutionize medicine since the earliest clinical trials, but a lack of delivery methods that are both safe and efficient has hampered progress. Gene therapy with viral vectors is effective at delivering nucleic acids to cells, but is associated with dangerous immunogenic responses and cancer-causing insertions into the genome. Viral vectors are also among the most prohibitively costly therapeutics in medicine. Polymeric vectors avoid these dangers and are made from inexpensive, off-the- shelf materials, but have been hindered by poor efficiency compared to viral vectors.

A benchmark polymer for in vitro nucleic acid delivery has been …

Religious Radio Broadcasting In Ukraine In The Context Of Digital Mediatisation And Social Transformation, Oleh Sokolovskyi, Olena Yurchuk

Occasional Papers on Religion in Eastern Europe

The study carries out a religious studies analysis of contemporary forms of spiritual communication implemented through audio and digital media platforms. The work highlights the particular features of organizing religious broadcasting under conditions of transformation of the information space, when traditional models of transmitting doctrine become integrated into new technological formats. Mechanisms of the formation of religious identity, ways of maintaining spiritual continuity, and strategies of interaction between religious institutions and their audiences are examined. An analysis is conducted of the structures that ensure access to spiritual content, including forms of catechetical communication, mentoring practices, and models of pastoral support …

The Cross And The Flag: Papal Diplomacy And John Paul Ii’S Struggle Against The Tyranny Of The Possible: A Review, John Grondelski

Occasional Papers on Religion in Eastern Europe

A review of Lebui, John Tanyi Nquah. The Cross and the Flag: Papal Diplomacy and John Paul II’s Struggle Against the Tyranny of the Possible. South Bend, Indiana: St. Augustine’s Press, 2024. Pp. xxvi + 322. PB, $30. ISBN 978-1-58731-143-7.

Who Can We Trust When They Are Watching? Lessons From Communist Surveillance For Today's Hybrid And Authoritarian Realities: An Interview Series, Katharina Kunter

Occasional Papers on Religion in Eastern Europe

This article explores the intersection of trust, surveillance, and political instrumentalization in authoritarian and hybrid warfare contexts, drawing on interviews with four contemporary witnesses from the Cold War era: Paul Mojzes, Laurens Hogebrink, Renate Ellmenreich, and Markus Meckel. Their experiences—spanning communist surveillance in the GDR, ecumenical diplomacy, and Western peace activism—reveal enduring challenges for churches, activists, and scholars engaging with partners in authoritarian regimes.

An Interdisciplinary Approach To Understanding The Social Ministry Of The Orthodox Church Of Ukraine In The Context Of Christian Theology And Socio-Humanitarian Sciences, Rostyslav Didukh

Occasional Papers on Religion in Eastern Europe

The article presents a comprehensive interdisciplinary scientific and theological analysis of the social ministry of the Orthodox Church of Ukraine (OCU) in the context of Christian theology and socio-humanitarian disciplines. Modern approaches of Orthodox theology to the social mission of Christianity ensure the integrity of the development of the human and society. The need to ensure the coherence of theological concepts of the Orthodox Church social teaching with the existing church and parish life, church educational mission, theological education, and social work is emphasized. Special attention is paid to the interdisciplinary connections of Orthodox theology, religious studies, psychology, pedagogy and …

Italian Missionary Activities In Georgia: Historical Legacy And Modern Inter-Religious Dialogue, Zaza Tsotniashvili

Occasional Papers on Religion in Eastern Europe

This article examines the historical development, cultural contributions, and contemporary significance of Italian missionary activities in Georgia spanning seven centuries, from medieval Catholic presence through the traumatic Soviet period to the post-independence revival. Drawing upon Georgian, Italian, and Vatican archival sources, including the manuscripts of Arcangelo Lamberti, Cristoforo de Castelli, and Michel Tamarati, the study provides comprehensive analysis of Italian Catholic missionaries' multifaceted engagement with Georgian society. The research demonstrates that Italian missionaries, particularly members of the Theatine, Capuchin, and Augustinian orders, played roles extending far beyond religious evangelization, functioning as diplomatic intermediaries, medical practitioners, linguistic documentarians, ethnographic observers, and …

Book Review: Ryszard Tyndorf With Rev. Zygmunt Zieliński, Wartime Rescue Of Jews By The Polish Catholic Clergy: The Testimony Of Survivors And Rescuers, John M. Grondelski

Occasional Papers on Religion in Eastern Europe

A review of Ryszard Tyndorf with Rev. Zygmunt Zieliński, Wartime Rescue of Jews by the Polish Catholic Clergy: The Testimony of Survivors and Rescuers. Lublin, Poland: Heschel Center, Wydawnictwo KUL, 2023. 2 vols., HB. ISBN 978-83-8288-087-8//088-5.

Measuring The Efficiency Of The Arts And Culture Sector Relative To Gdp: A State-Level Analysis Of The United States, Ameerkhan Jaffar Khan Khader Khan

Selected Full-Text Master Theses 2021-

Arts and cultural production contributed $1.17 trillion to United States gross domestic product in 2023, 4.2% of the national total, but that contribution is spread very unevenly across states, and the official statistics describe how large the sector is rather than how efficiently it operates (Bureau of Economic Analysis, 2024). This study asks how efficiently each state convert growth in arts and culture employment into growth in value added, how many inputs the efficiency model can carry before it stops distinguishing 51 observations, and whether observable state characteristics explain the differences found. The analysis uses 2023 state-level data for all …

Using “Big Data” And Non-Linear Machine Learning To Infer Groundwater Contamination Mechanisms Across A Spatially Extensive, Geologically Heterogeneous Region, Ioan Petculescu, Anna Majury, R. Stephen Brown, Kevin Mcdermott, Paul Hynds

Research Outputs: 2025-Present

Groundwater accounts for approximately 98% of available freshwater, with >2 billion people relying on it as a primary drinking water source. Notwithstanding its importance, specific groundwater quality parameters - namely microbial concentrations and non-Escherichia coli coliforms (NEC) - remain understudied. The current study sought to address this gap by modelling three distinct Contamination Indices (CI) corresponding to E. coli concentration, NEC concentration, and the NEC:E. coli concentration ratio. CIs were developed for south Ontario (115,693 km²) using ∼1 million samples from ∼290,000 wells collected between 2010 and 2021. To permit modelling, CIs were linked to 50 subregion-specific variables …

Segmentation Of Household Behavioural Types Associated With Food Waste Generation In The Republic Of Ireland, Courage Y. Krah, Paul Hynds, Anushree Priyadarshini

Research Outputs: 2025-Present

Despite the growing number of interventions aimed at reducing household food waste (HFW), many remain overly generalised and fail to adequately account for the heterogeneous routines, motivations, and disposal contexts that shape waste generation. This study, therefore, aimed to identify behavioural types in the Republic of Ireland (ROI) based on HFW habits to inform more targeted and effective reduction strategies. Using survey data from 966 households, Principal Component Analysis (PCA) and hierarchical clustering were applied to identify co-disposal patterns of food groups and to segment households into behaviour clusters. The PCA identified four co-disposal patterns, while clustering yielded four household …

A Glimpse Of Early Ellensburg, Washington From The 1980'S Excavations At 45kt800, Leah M. Shenyer

All Master's Theses

The Robber’s Roost site, located in the town of Ellensburg, Washington, was excavated in a partnership between Central Washington Archaeological Survey and Kittitas County Youth Services in the summers of 1986 and 1988. In 2023, the collection consisted of 110 boxes of artifacts including bottle glass, ceramics, leather, and faunal remains, with no significant prior analysis and little information on the dig itself. The purpose of this thesis is to document this poorly-known excavation project and gain a better understanding of Ellensburg’s history through analysis of the artifacts recovered. I compiled all the available paper records and communicated  with past …

Anaerobic Digestion Of Food Waste Components: Modeling Biogas Production, Opeyemi E. Adelegan

Civil Engineering Dissertations

Food waste constitutes the single largest component of municipal solid waste landfilled in the United States — approximately 22% of 292.4 million tons generated in 2018 — and its anaerobic decomposition releases methane, a greenhouse gas with global warming potential approximately 27–30 times that of carbon dioxide over a 100-year horizon (IPCC, 2021). Anaerobic digestion (AD) offers an alternative management pathway that recovers energy and produces nutrient-rich digestate, but AD performance varies by as much as five-fold across food waste streams (130–630 m³ CH₄ per Mg VS added), and existing predictive tools either treat food waste as a …

Analyzing Geographic Distribution And Distressed Community Index Trends In Black Dermatologists Of The Southeast United States, Laci Turner, Charlotte Mcrae, Michael Anderson, Lamario Williams, Tiffany Mayo

UAB Huntsville Research Day - All Presentations

2026 research poster

Immuno-Toxic Effects Of Zinc Oxide Nanoparticles And Protective Role Of Moringa Olifera On Thymus Of Male Albino Rats, Marwa Abdelsalam Abdallah, Alaa Fehaid, Aml Abdelmonem Halawa, Mmdouh Mohammed Abou Ealmagd

Mansoura Veterinary Medical Journal

Background and Aim The present study aims to evaluate the protective role of Moringa olifera (MO) extract against Zinc Oxide Nanoparticles (ZnO NPs) induced immunotoxicity in male albino rats. Methods Forty-eight Male albino rats were divided into six groups. The 1st group (control) orally received distilled water. The 2nd group received 100 mg/kg of MO extract. The 3rd group was administered 200 mg/kg B.W ZnO NPs. The 4th group received 200 mg/kg B.W ZnO NPs in combination with 100 mg/kg of MO extract. The 5th group received 400 mg/kg B.W ZnO NPs. The 6th group received 400 mg/kg B.W ZnO …

Occupational Identity & Career Preparation, Leah Shea Simpkins, Karen R. Puckett

Pedagogicon Conference Proceedings

Regardless of the profession, having occupational identity is highly important. Students are in need of preparing themselves for their future careers whilst in college. Having a career portfolio is a great tool for students to have upon graduation which showcases their occupational identities regarding future career preparedness.

Teaching Durable Skills In A School Principal Certification Program, Kevin Hub

Pedagogicon Conference Proceedings

Eastern Kentucky University (EKU) offers principal certification through a specialized Principal Certification Cohort Degree program. One component within this academic program is teaching durable skills through a deeper dive into curriculum, a broader range of field experiences, and the development of durable skills through a series of experiential learning assignments.

Harnessing Ai For Medical Education: A Faculty Development Series For Pre-Clinical And Clinical Educators, April Hatcher, Tama The

Pedagogicon Conference Proceedings

This manuscript describes a faculty development series designed to integrate artificial intelligence (AI) into medical education. Faculty participants discussed practical applications of AI, student perspectives on their use of AI, and innovative collaborative projects with local faculty. This short series was scaffolded as an introduction to AI for medical educators.

Tek Faculty Fellows: Building Faculty Confidence In Teaching Durable Skills Through Transdisciplinary Collaboration, Shawna Felkins, Madeline Aulisio Miller, Trey Conatser, Diane Parr

Pedagogicon Conference Proceedings

The TEK Faculty Fellows program was created to support faculty in the design of new courses or enhancement of existing courses to engage students in transdisciplinary learning and skill-building. This paper shares early evaluation findings and practical strategies to support faculty in making durable skills more visible in the classroom.

Beyond The One Shot: Plan A Library Workshop Week For Any Course, Melony Shemberger

Pedagogicon Conference Proceedings

Writing a research paper requires solid information literacy skills. This article will guide the design of a weeklong library focus into courses to strengthen students' information literacy. Lessons for embedding essential information literacy components into a course will be provided to help learners find, evaluate, and format sources and citations.