Digital Commons Network^™

Analyzing And Understanding America’S Involvement In The Global War In Terror Through The Oral Histories Of Its Veterans And Other Sources, Bryce Edwards

Distinguished Undergraduate Researcher Program

From 2001 to the early 2020s, the United States and its allies have consistently engaged in political, military, counterinsurgency, and nation building operations in nations such as Afghanistan and Iraq. The efforts of this coalition first rallied to combat the threat of global terrorism after September 11th, yet it would then develop in decades-long assignment to rebuild these countries and their institutions with fundamental (and foreign) western values. This thesis intends to examine the conflict by conducting oral histories of its many veterans, to better understand their lived experience. These interviews will be supported by scholarly works from those involved …

Gullah Geechee, Progenitors For African North American Maternal Lineage, Jennifer Caldwell, Imani Sykes, Robbie Beyl, Tomilowo Abijo, Kiara Charles, Fatimah Jackson

Distinguished Undergraduate Researcher Program

African American ancestral lineages are marked by resilience, shaped by centuries of forced migrations, the Transatlantic and domestic slave trades, and subsequent movements within the United States. These historical events have influenced both the cultural and genetic diversity of Legacy African Americans. This study examined mitochondrial DNA (mtDNA) haplogroups among 189 participants—79 Gullah Geechee and 110 African Americans—to explore the Gullah Geechee as potential progenitors of other Legacy African North American lineages. Haplogroup analysis revealed L2 and L3 as the most frequent among both groups, comprising 34.6% and 38.8% in African Americans and 28.0% and 54.7% in Gullah Geechee, respectively. …

Freshwater Mussels Of Louisiana: A Field Guide, Franchesca Ruiz, Garrett Hopper

Distinguished Undergraduate Researcher Program

Freshwater mussels (Order Unionidae) are important animals that provide valuable ecosystem functions and services. Due to a multitude of factors such as habitat modifications and habitat destruction related to human population growth many mussel populations are declining throughout the United States increasing the need for public awareness. Louisiana is home to 63 mussel species, but most residents are not aware of their presence, importance, or state of imperilment. We addressed this by creating a field guide to the freshwater mussels of Louisiana. Our goals include providing a resource for accurate freshwater mussel field identification, increasing public and scientific awareness of …

Structural Determination And Regulatory Mechanisms Of Rice Lipoxygenase-1, Lillie Ballanco, Nathaniel Gilbert, Adam Offenbacher

Distinguished Undergraduate Researcher Program

Lipoxygenases (LOXs) are non-heme iron containing enzymes that catalyze the oxygenation of polyunsaturated fatty acids (PUFAs) such as linoleic acid (LA). These lipoxygenase enzymes are found in both plants and animals. In humans, LOXs have been linked to inflammatory diseases such as asthma, atheroscelerosis, and allergic rhinitis. Plant LOXs have been primarily linked to the growth, development, and stress response of the plant. This paper focuses on Oryza sativa lipoxygenase-1 (OsLOX1), an enzyme found in rice (Oryza sativa). OsLOX1 has been associated with enhanced drought tolerance in rice and may play a role in regulating growth under water-limited conditions. Understanding …

Analysis Of The Pervasiveness Of Per- And Polyfluoroalkyl Substances (Pfas) And Their Relationship With The Incidence Of Neurological Health Disorders, Emma Waters

2026 Research Poster Competition

Per- and polyfluoroalkyl substances (PFAS) are a contaminant of emerging concern due to their chemical structure that afford a plethora of issues with regards to degradation on environmental and metabolic fronts. PFAS are amphiphilic and contain a carbon-fluorine bond, which complicates their movement through the environment and ensures their longevity in biological systems. Their persistence in biological systems has led them to be marked as “forever chemicals” and have emphasized them as a priority area for research in recent years. Current work on PFAS relationships to human health have pointed to some causes for concern. Much of the research on …

The Prevalence Of Diabetic Retinopathy In American Indians Or Alaska Natives And Non-Indigenous Americans: A Systematic Review And Meta-Analysis., Caberry W. Yu, Keean Nanji, Anubhav Garg, Michele Zaman, Jane Jomy, Abdullah El-Sayes, Catherine Sun, Shreyas Bhat, Mark Phillips, Dena Zeraatkar, Jinhui Ma, Enrico Borrelli, Sunir J Garg, David H. Steel, Tien Yin Wong, Sobha Sivaprasad, Charles C. Wykoff, Varun Chaudhary

Wills Eye Hospital Papers

TOPIC: To estimate the prevalence of diabetic retinopathy (DR) in adult American Indian or Alaska Native (AIAN) and non-AIAN patients with diabetes.

CLINICAL RELEVANCE: Although diabetes mellitus is more prevalent among AIAN patients compared with non-AIAN patients, the evidence is inconsistent regarding whether AIAN patients have a higher prevalence or severity of DR.

METHODS: We searched Ovid MEDLINE, EMBASE, and Web of Science databases from inception through February 23, 2025. We included primary studies evaluating the prevalence of DR in Americans with diabetes. The prevalence of (1) DR, (2) diabetic macular edema (DME), (3) proliferative diabetic retinopathy (PDR), (4) vision-threatening …

Cheshire Advisory Council Agenda & Minutes 2026, Carl Majewski

Advisory Council

No abstract provided.

Cytoprotective Role Of Octacosanol In Lipopolysaccharide-Induced Inflammation, Jingrong Tang, Zhi Hong Yang, Wenling Li, Huaitian Liu, Diego Lucero, Denis Sviridov, Olivia White, Julia Kun, Yoh Suke Mukouyama, Alan T. Remaley

Physiology Faculty Publications

Inflammation and endothelial dysfunction are key steps in the pathogenesis of atherosclerosis. Octacosanol (C₂₈H₅₈O, OCT), a very-long-chain saturated aliphatic alcohol (VLCA) with 28 carbons, is the main component of policosanol, a nutraceutical mixture of VLCAs (C20-C34) extracted from plants. Polycosanol in animal models is known to reduce atherosclerosis, but its mechanism of action remains unclear. This study investigates the pathways by which OCT alleviates LPS-induced inflammation in primary human aortic endothelial cells (HAECs). After overnight pretreatment with purified OCT, inflammation in HAECs was induced by lipopolysaccharide (LPS) at 100 ng/ml. The effects of OCT on the …

Agricultural Evidence Synthesis At A Critical Juncture: Quality Gaps And Implications For Evidence-Based Agriculture, Chao Cai, Jane Yatcilla, Justyna Czader, Sylvie Brouder, Jeffrey Volenec

Libraries Faculty and Staff Scholarship and Research

Systematic reviews and meta-analyses have become essential tools for synthesizing evidence to guide agricultural policy and practice, yet whether these syntheses are themselves conducted with sufficient rigor has rarely been systematically assessed. This study provides a field-wide assessment of reporting quality in agricultural evidence synthesis, examining whether existing reviews are conducted with sufficient transparency and rigor to support the policy and practice decisions they are meant to inform. We drew a random sample of 244 systematic reviews and meta-analyses from a bibliometric dataset of 1,709 articles published between 1997 and 2023, evaluating reporting quality using a 12-indicator rubric across four …

A Zinc Chelate Of Lysine/Glutamic Acid Reduces Alcohol-Induced Ciliary Dysfunction, Emily Do, Daren L. Knoell, Christopher Bauer, Deanna Mosley, Deandra R. Smith, Derrick R. Samuelson, Todd A. Wyatt

Journal Articles: Environmental, Agricultural & Occupational Health

Alcohol misuse is a known risk factor for pneumonia, and up to 50% of individuals who misuse alcohol are zinc deficient. Chronic alcohol misuse can lead to alcohol-induced ciliary dysfunction (AICD), preventing effective mucociliary clearance and protection against lung infection. Because zinc salts fail to alter AICD, we hypothesized a form of zinc (Zinpro Zinc LG) with enhanced cell uptake would protect against AICD. Human and mouse airway epithelial cells were treated with 50 mM ethanol for 1-24 h followed by the ciliostimulatory agents. Cilia beat frequency (CBF) and cAMP-dependent protein kinase (PKA) activity were assayed. Cyclic AMP or beta …

Comprehensive Analytical Investigation Of Tetrahydro-4h-Chromene And Dihydropyridine Derivatives, Ryan J. Burk

Chemistry & Biochemistry Dissertations

Novel calcium channel blockers (CCBs) with dihydropyridine (DHP) or tetrahydro-4H-chromene moieties are often chiral, so effective enantiomer separation methods are needed for continued drug development. The purpose of this dissertation is to outline a comprehensive method development model for the chiral separations of DHPs and tetrahydro-4H-chromene derivatives. The scope of this dissertation is to address analytical challenges during initial synthesis, chiral separations, and data analysis during post-processing for this class of chiral compounds. The first section focuses on the method development strategies for separations of DHPs in the sub/supercritical fluid (SFC) and normal phase modes with the 2-hydroxypropyl-β-cyclodextrin stationary phase. …

Labor Savings From Mechanical Rice Transplanting In Bangladesh, India, Nepal, And The Philippines: A Systematic Review And Meta-Analysis, Rodrigo S. David

ASEAN Journal on Science and Technology for Development

Rice production in South and Southeast Asia faces serious challenges, including acute labor shortages and rising wages, which threaten regional food security. Mechanical rice transplanting offers a promising solution; however, evidence on labor savings, especially region-specific data, remains inconsistent. This systematic review and meta-analysis aimed to quantify labor savings from mechanical versus manual transplanting across Bangladesh, India, Nepal, and the Philippines.

Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic search was conducted across four major scientific databases (2000–2026) using Boolean search terms for mechanical transplanting and labor outcomes. Of 284 initial records, 52 met eligibility …

Affordable Infill Housing For Zillennials: Enhancing Urban Mobility Through Walkable And Bikeable Access In Jakarta Metropolitan Area, Mewan Indra, Arif Kusumawanto, Agus Hariyadi

ASEAN Journal on Science and Technology for Development

Rapid urbanization in developing countries has intensified housing challenges for younger generations, particularly Zillennials (aged 24–34), who demand affordable, accessible, and sustainable living environments. This study investigates the optimal location for small-scale housing integrated with large-scale developments in the Jakarta Metropolitan Area (JMA), emphasizing mobility as the primary criterion. The research is guided by a conceptual framework that synthesizes compact city principles, the 15-minute city concept, and Zillennial lifestyle preferences, with walkability and bikeability serving as mediating variables. Mobility simulations were conducted using the Urban Modeling Interface (UMI), applying Walk Score parameters to evaluate walking and cycling accessibility. Six simulation …

Climate And Seasonal Influences On Indo-Pacific Sea Level: Insights From 30 Years Of Satellite And Tide Gauge Data, Karlina Triana

ASEAN Journal on Science and Technology for Development

We analyze Indo-Pacific sea-level variability using monthly satellite altimetry (1993–2025) validated against records from 16 tide-gauge stations. Cross-comparisons show strong agreement, especially in the western Pacific, confirming the reliability of altimetry for regional assessments. Seasonal SLA variability is largest in the Bay of Bengal and South China Sea and reflects monsoonal forcing, whereas interannual fluctuations in the eastern Indian and western Pacific oceans are dominated by ENSO and modulated by PDO. Harmonic decomposition isolates annual and semi-annual cycles, and an EOF/PCA framework identifies the leading modes: EOF1 (30.8%) captures basin-scale interannual variability and EOF2 (20.9%) reflects the seasonal cycle. Spectral …

The Impact And Sustainability Of A School Improvement Grant On Student Outcomes In An Elementary Setting, Tiesha Denise Reed

Theses and Dissertations

The purpose of the study was to examine the impact and sustainability of the School Improvement Grant (SIG) Transformation Model and to determine its impact on a low-performing elementary school. The research study used a quantitative research design to investigate the effects of the SIG on student achievement and school annual reporting data across three time periods: pre-intervention (2014-2015), post-intervention (2016-2017), and six years after the grant ended (2022-2023). The research design was appropriate because it allowed the researcher to collect archival data and examine potential differences across time periods. The independent variable was the three time periods, and the …

Practicing Contemporary Documentation: An Analysis Of Historic Influences And Personal Inspirations, Zoee D. Rasso

Theses and Dissertations

For my Honors Thesis, I proposed and created a solo exhibition of my artwork, researching the inspiration behind this work to determine its place within in the context of contemporary art history. My work as an artist centers on stylized, psychologically charged portraits of birds. Looking at art history, birds as artistic subjects are historically rooted in documentation, from scientific illustrations and game paintings to ukiyo-e. Analyzing my own creative influences such as James Audubon, Walton Ford, and Safet Zec, this Thesis explores my artistic background and influences, examining how I have developed as an artist over my tenure at …

The Returns On Educational Investment: Military Retention Among Mid-Grade Enlisted Soldiers After Army-Funded Degree Completion, Robert Kenneth Bandy Jr.

Theses and Dissertations

The U.S. Army Tuition Assistance (TA) program represents a substantial investment in the education and professional development of enlisted soldiers, yet limited empirical research has examined retention outcomes among soldiers who complete degrees using TA. The purpose of this quantitative correlational study was to examine the relationship between selected demographic and educational characteristics and time-to-separation among enlisted U.S. Army soldiers who completed a degree using TA between fiscal years 2023 and 2025. Guided by Human Capital Theory, the study used archival administrative data from the Army Continuing Education Division (ACED) and the Integrated Personnel and Pay System-Army (IPPS-A). A stratified …

Analysis Of Risk Factors And Current Programs For Addressing Injuries In Children And Adolescents, Jahfel Nial Jones Iii

Theses and Dissertations

Unintentional injuries are a leading cause of morbidity and mortality among children and adolescents in the United States. These injuries result from various causes, including motor vehicle crashes, falls, suffocation, and poisoning. This capstone project examines the prevalence, risk factors, and prevention strategies for unintentional injuries among infants, children, and adolescents. Using a public health approach, this research explores evidence-based interventions and community-based programs that effectively reduce injury-related mortality. The project also incorporates data and insights from the Safe Kids Columbus program at Piedmont Columbus Regional, where various injury prevention initiatives have been implemented.

Findings revealed that motor vehicle crashes …

Dynamics Of Single-Walled Carbon Nanotubes In Structured Complex Fluids, Sepehr Yari

Open Access Master's Theses

Cancer survival depends strongly on the stage at which the disease is detected, motivating the development of biosensors capable of identifying early changes in cellular state. Single-walled carbon nanotubes (SWCNTs) are promising intracellular biosensors because their intrinsic near-infrared fluorescence, photostability, and tunable surface chemistry and lenght enable prolonged measurements in living cells. Disease such as cancer can progress and alter intracellular physical properties, suggesting that SWCNT motion may provide a physical readout of changes in cellular state. Interpreting this motion is challenging, however, because the cytoplasm is structurally heterogeneous and contains both passive fluctuations and active transport processes. As a …

Papillary Thyroid Carcinoma With Cervical Lymph Node Metastasis Case Study, Dasaani Brown

Bachelor of Science in Diagnostic Ultrasound Projects

Papillary thyroid carcinoma (PTC) is the most common form of thyroid malignancy and typically presents as a painless, progressively enlarging neck mass. This case study describes a 25-year-old male presenting with a palpable left-sided neck mass, unexplained weight loss, and shallow breathing during sleep. Diagnostic evaluation with ultrasound and computed tomography (CT) revealed bilateral thyroid nodules and extensive cervical lymphadenopathy. The findings were deemed highly suspicious for malignancy. Ultrasound-guided fine needle aspiration (FNA) biopsy confirmed the diagnosis of PTC. The patient subsequently underwent total thyroidectomy with bilateral neck dissection. The overall prognosis is favorable, as PTC is amenable to treatment …

Papillary Muscle Rupture: Case Study, Mandy Wu

Bachelor of Science in Diagnostic Ultrasound Projects

This study evaluates how effective echocardiography is in diagnosing papillary muscle rupture and guiding management in patients with suspected acute cardiac complications. This case study describes a 43-year-old autistic male presenting with pneumonia and progressive respiratory distress. Diagnostic evaluation included transthoracic and transesophageal echocardiography to assess cardiac function and valvular integrity. Echocardiography confirmed papillary muscle rupture with severe mitral regurgitation. Due to high surgical risk, the patient underwent MitraClip placement as a less invasive intervention. Despite treatment, the patient experienced rapid clinical deterioration and ultimately passed away shortly after intervention. Papillary muscle rupture is a life-threatening condition requiring rapid recognition, …

Autosomal Dominant Polycystic Kidney Disease (Adpkd) Case Study, Nhu P. Tang

Bachelor of Science in Diagnostic Ultrasound Projects

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disorder that is present in adults and is characterized by progressive cyst development. It leads to chronic kidney disease (CKD) and end-stage renal disease (ESRD) due to loss of renal function. This case presents a 54-year-old male with known ADPKD and nephrolithiasis who presented with left flank pain and hypertension. Ultrasound evaluation demonstrated enlarged bilateral kidneys with numerous cysts replacing normal renal tissue and a kidney stone within the left kidney. For management, the patient was placed on medications and has been on the transplant list. This case …

Perioperative Role Of Vascular Ultrasound In Sta–Mca Bypass For Moyamoya Disease: A Case Study, Madeleine Ramos

Bachelor of Science in Diagnostic Ultrasound Projects

Moyamoya is a chronic progressive cerebrovascular disorder characterized by gradual stenosis and eventual occlusion of the intracranial vessels. The disease most commonly begins in the intracranial internal carotid arteries and may extend to involve the anterior, middle, and posterior cerebral arteries. As arterial narrowing progresses, a network of fragile collateral vessels forms at the base of the brain, creating the characteristic “puff of smoke” appearance seen on angiographic imaging.

This case study reviews a 43-year-old male who presented with an acute ischemic stroke involving a functionally occluded right M1 segment of the middle cerebral artery (MCA), later determined to be …

Congenital Diaphragmatic Hernia: A Case Report, Keira Martin

Bachelor of Science in Diagnostic Ultrasound Projects

The Congenital Diaphragmatic Hernia is an uncommon fetal defect of the diaphragm discovered in utero, where it does not complete development, allowing abdominal viscera to herniate into the thorax. This case study describes the procedure of using ultrasonography on a 41-year-old female who is pregnant with a fetus with a congenital diaphragmatic hernia. The procedure completed was a detailed anatomy scan, which is a transabdominal ultrasound to rule out pathology of the fetus, uterus, cervix, and ovaries. The ultrasound discovered a defect in the left side of the fetal diaphragm, allowing the stomach and a portion of the left liver …

Progression To Critical Stenosis In An Unmonitored Bicuspid Aortic Valve: Case Report, Rylen Manuel

Bachelor of Science in Diagnostic Ultrasound Projects

Bicuspid aortic valve (BAV) is the most common congenital heart defect, but it can remain undiagnosed until adulthood. This case study describes a 36-year-old male who presented for a transthoracic echocardiogram to evaluate systolic murmur without any symptoms. The patient vaguely recalled a diagnosis of BAV in his childhood but had not received any cardiac evaluation for over two decades and no documentation of the diagnosis was available in his medical record. Echocardiography confirmed a BAV with cusp fusion and revealed critical aortic stenosis, moderate aortic regurgitation, mild dilation of the ascending aorta, and severe left ventricular hypertrophy. The severity …

Medullary Nephrocalcinosis In A Patient With Medullary Sponge Kidney: A Case Report, Sagal Khalif

Bachelor of Science in Diagnostic Ultrasound Projects

Medullary nephrocalcinosis is characterized by calcium deposition within the renal medulla and is often associated with recurrent nephrolithiasis, metabolic, or congenital renal conditions. This case involves a 70-year-old female patient whose medical history includes both a prior diagnosis of medullary sponge kidney and multiple occurrences of kidney stone formation. She presented for evaluation of dysuria and hematuria. Renal ultrasound was performed and demonstrated echogenic renal pyramids, consistent with medullary nephrocalcinosis. Additional computed tomography (CT) imaging was performed to assess the extent of the calcification and evaluate for new or persistent kidney stones. This case demonstrates the importance of continued imaging …

The Critical Role Of Transthoracic Echocardiography In The Evaluation Of Acute Renal Infarction, Gurjeet Dosanjh

Bachelor of Science in Diagnostic Ultrasound Projects

Acute renal infarction is a rare and frequently misdiagnosed condition that often presents with nonspecific abdominal or left flank pain. Renal infarction is commonly associated with cardioembolic etiologies, making echocardiography evaluation essential. In the case presented, a 60-year-old male had presented with a sudden onset of left flank pain, and a computed tomography (CT) confirmed renal infarction. A transthoracic echocardiogram was performed to assess cardiac structures, function, and potential intracardiac thrombus. Results showed the diagnosis of moderately reduced left ventricular systolic dysfunction with exclusion of a cardioembolic source, timely investigation of anticoagulant therapy, and a reduced risk of irreversible damage. …

An Ovarian Cancer Case Study, Amina Farah

Bachelor of Science in Diagnostic Ultrasound Projects

Ovarian epithelial carcinoma (OEC) is the most common and lethal form of ovarian cancer, often presenting with subtle or nonspecific symptoms. This report describes the case of a 31-year-old postpartum woman with a six-month history of abdominal pain and bloating. This case highlights the limitations of imaging modalities in the evaluation of large lesions. A focused abdominal ultrasound examination was performed, revealing an intra-abdominal vascular mass. Findings were compared with prior and subsequent Computed Tomography (CT) scans to assess the lesion’s origin, given the limitations of ultrasound. Sonographic evaluation demonstrated a large mixed heterogenous mass with thick septations and internal …

Renal Cysts On Ultrasound, Jocelyn Rios De La Cerda

Bachelor of Science in Diagnostic Ultrasound Projects

Renal cell carcinoma is a malignant condition that impairs kidney function and is commonly associated with risk factors such as smoking and hypertension. This case study examines an 83-year-old female with a significant medical history who presented for further evaluation of an indeterminate renal mass previously identified on CT and MRI imaging, which revealed a benign cyst and a separate solid lesion with concerning characteristics. A renal ultrasound demonstrated a simple cyst and a distinct hypoechoic, ill-defined lesion, raising concern for possible neoplasm. Follow-up imaging with contrast-enhanced CT was recommended for further characterization. This case highlights the importance of ultrasound …

A Large Recurrent Pseudoaneurysm Of The Superficial Femoral Artery: A Case Report, Virginia Engel

Bachelor of Science in Diagnostic Ultrasound Projects

Peripheral arterial aneurysms are rare vascular pathologies characterized by dilation of all three arterial wall layers within an extremity. When a peripheral aneurysm ruptures, the extravasation can be contained by the surrounding soft tissues of the extremity, forming a pseudoaneurysm that can continue to grow. In this case report, a 60-year-old male presented with a ruptured left superficial femoral artery (SFA) aneurysm that formed a large recurrent pseudoaneurysm, with concomitant right SFA and popliteal artery aneurysms. Multiple imaging modalities (computed tomography angiography (CTA), angiography, ultrasound) and treatment methods (autologous vein bypass, endovascular stent) were used throughout this case. This case …