Digital Commons Network^™

Fcil Basics: Key Concepts, Fcil Librarianship, Fcil Resources & An Introduction To Treaty Research, Loren Turner, Meredith Capps, Charlotte Daugherty

Articles

No abstract provided.

Noneconomic Tort Damages And Biased Beliefs About Vulnerability To Harm, Roseanna Sommers

Articles

The American tort system aspires to provide fair compensation to injured plaintiffs, regardless of socioeconomic status, race, religion, or gender. Recent experimental evidence from psychology suggests, however, that factfinders consistently judge identical harms as less severe when experienced by individuals of lower socioeconomic status (SES). People presume, for instance, that a paper cut hurts a wealthy person more than a less well-off person, that domestic violence inflicts greater suffering on a high-SES woman than a lower-SES woman, and that bullying harms a fiveyear- old from a high-SES family more severely than one from a low- SES family. This Essay examines …

What's The Point Of Reparation?, Daniel Fryer

Articles

Despite its ancient history in philosophical and legal thought, importance to progressive social movements, and relative simplicity as a notion of fairness—if you break something, you ought to fix it—reparative justice is largely misunderstood. This is problematic given increasing calls for reparation from historically disadvantaged groups. Rather than assessing the validity of these claims, this Article addresses a fundamentally antecedent issue: what’s the point of reparation? Rejecting arguments that claim reparation is about compensation, supplementing distributive justice, and reconciliation, I argue that the point of reparation is to repair unjust social relations created by past wrongdoing. The relational theory of …

From Relic To Relevance, The Resurgence Of Tariffs, Reuven S. Avi-Yonah

Articles

Modern legal scholarship has largely relegated tariffs to economic analysis, overlooking their legal and policy significance. This Article challenges that view by examining tariffs as a potential pillar of fiscal policy, exploring their viability as a revenue source alongside or in place of traditional income and corporate taxation. While historically central to U.S. government funding, tariffs’ importance diminished with the rise of income taxation and trade liberalization. However, their recent resurgence as a tool for trade protection raises broader questions about their role in national economic strategy.

This Article critically assesses the feasibility of a tariff-based tax system, drawing on …

An Incidental Standard For Medical Ai, Nicholson W. Price Ii

Articles

Medical AI is poised to make a major difference in the provision of health. It brings major challenges, though: how can developers and implementers ensure that it will work safely and effectively—especially within the context of complex and highly variable health-care systems? Standards provide one key tool, potentially providing guidelines for everything from privacy to accuracy to how AI interacts with human clinicians. This Essay considers the last of these, describing a powerful quasi-standard from a surprising source: an FDA guidance document that tells developers when certain AI systems are not considered medical devices, and are therefore not regulated by …

Greater Body Dissatisfaction At Admission Is Associated With Lower Bmi At Discharge In Anorexia Nervosa: Predictive Validity Of The Eating Pathology Symptoms Inventory., Danielle A N Chapa, Marianna L. Thomeczek, Brianne N. Richson, Alan Duffy, Kara A. Christensen Pacella, Kelsie T. Forbush, Renee D. Rienecke, Dan V. Blalock, Sara R. Gould, Victoria L. Perko, Philip S. Mehler

Manuscripts, Articles, Book Chapters and Other Papers

People with anorexia nervosa (AN) engage in dietary restriction and other weight loss behaviors that result in dangerously low body weight, leading to an increased risk for mortality and medical complications. Weight gain is one of the most important indicators of treatment progress and recovery for AN. There are limited predictors of weight gain for patients with AN, making it difficult for clinicians to anticipate which patients are likely to respond favorably to treatment. Thus, there is a need to identify additional, potentially modifiable predictors of weight gain within a higher level of care for AN. This study tested the …

A Comparison Of Poly(Methyl Methacrylate) And Silorane-Based Cements As Carriers For Local Doxorubicin Delivery., Grahmm A. Funk, Elizabeth M. Menuey, Zachary D. Denton, Dalan M. Pittz, Alejandro Parrales, Tomoo Iwakuma, Kathleen V. Kilway, Terence E. Mciff

Manuscripts, Articles, Book Chapters and Other Papers

Orthopedic osteosarcomas and metastatic lesions can be difficult to treat with systemically delivered chemotherapy agents alone. Following removal of the primary tumor, implantation of cement to fill the lesion is often done to stabilize weight-bearing bones. One of the commonly used treatments to address osteosarcoma is systemic delivery of doxorubicin. Therefore, research on the incorporation and release of efficacious doxorubicin for local delivery from cement is important. Poly(methyl methacrylate) (PMMA)-based bone cements are the gold standard in orthopedics but have inherent disadvantages. Efforts to overcome some of these deficiencies led to the development of a novel silorane-based biomaterial (SBB). This …

Association Of N-Terminal Pro-Brain Natriuretic Peptide With Ckd Progression In The Ckd In Children Study., Alexander Kula, David K. Prince, Joseph T. Flynn, Susan L. Furth, Bradley A. Warady, Tamara Isakova, Derek Ng, Jeese Seegmiller, Rob Christenson, Nisha Bansal

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Las Dos Teresas: How Women’S Critiques Of Imperialism And Patriarchy Transformed The Spanish Anarchist Movement, Stephanie Mendez

Women, Gender, and Sexuality Studies Undergraduate Honors Theses

The central question my thesis explores is how women’s participation in the Spanish anarchist movement in the late nineteenth century to early twentieth century transformed the meaning of anarchism and the anarchist movement. The anarchist movement failed to adequately acknowledge structural inequality between men and women. Women anarchists, such as Teresa Claramunt and Teresa Mañé, acknowledged this discrepancy by reimagining the practice of anarchism. They argued for the genuine expression of total liberation. This could only be achievable through the recognition of women’s subordination. They critiqued the role of patriarchy in maintaining women’s subordination. Through their vision for total liberation, …

Rationale And Trial Design Of Ribolaris: A Phase Ii Trial Of Neoadjuvant And Adjuvant Ribociclib Plus Endocrine Therapy For Clinically High-Risk Hr+/Her2-Negative Breast Cancer, Paul Cottu, Cynthia X Ma, Et Al.

2020-Current year OA Pubs

BACKGROUND: Despite advances in endocrine therapy, patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (eBC) remain at risk of recurrence (ROR). Chemotherapy is often used in high-risk cases, but not all patients benefit.

OBJECTIVES: To evaluate whether chemotherapy can be safely omitted in patients with stage II, grade 2/3 HR+/HER2- eBC who convert to low genomic risk (ROR-low) following neoadjuvant ribociclib plus letrozole.

METHODS: RIBOLARIS (NCT05296746) is an open-label, multicenter phase II trial in patients with stage II, grade 2 or 3, HR+/HER2- eBC defined as high risk based on a Ki-67 index ⩾20% …

08.05.04. Bridled Tern, Onychoprion Anaethetus, R. Zambrano, Ann Hodgson, Florida Ornithological Society

08.05. <em>Laridae</em> - Gulls, Terns, and Skimmers

The Bridled Tern is very common offshore in the Gulf of Mexico and on the Atlantic coast as far north as Virginia.

08.05.02. Brown Noddy, Anous Stolidus, Bill Pranty, Ann Hodgson, Florida Ornithological Society

08.05. <em>Laridae</em> - Gulls, Terns, and Skimmers

The Brown Noddy has a pantropical range, occuring on islands in southern Florida, the Caribbean, and Central America.

08.05.03. Sooty Tern, Sterna Fuscata, M. Hedden, Ann Hodgson, Florida Ornithological Society

08.05. <em>Laridae</em> - Gulls, Terns, and Skimmers

The Sooty Tern is pelagic; all its nesting colonies are located on remote subtropical and tropical islands.

The Protective Power Of Psychological Resources In Mitigating Burnout And Enhancing Flourishing, Dylan R. Polkinghorne, David J. Radosevich, Deirdre M. Radosevich, Dianne D. Murphy, Laken James, Sue S. Craver

Management Faculty Research and Publications

Purpose

This study explores how burnout mediates the relationships between critical psychological resources, specifically resilience, flow and self-efficacy, and flourishing in contemporary work environments.

Design/methodology/approach

Data from 374 participants, including undergraduate students at a regional comprehensive university in the Midwest and full-time working adults in the USA, were analyzed using mediation analysis in MPlus 8.11 to assess the indirect and direct effects among burnout, psychological resources and flourishing in a work environment.

Findings

Results indicate that self-efficacy significantly predicts lower burnout levels and higher flourishing. Resilience and flow were negatively associated with burnout, reducing its impact; however, the direct effects …

Cutibacterium Adaptation To Life On Humans Provides A Potential C Acnes Infection Biomarker, Md Shafiuddin, Wen-Chi Huang, Gabriel William Prather, Jeffrey Ryan Anton, Andrew Lawrence Martin, Sydney Brianna Sillart, Jonathan Z Tang, Michael R Vittori, Michael J Prinsen, Jessica Jane Ninneman, Chandrashekhara Manithody, Jeffrey P Henderson, Alexander W Aleem, Ma Xenia Garcia Ilagan, William H Mccoy 4th

2020-Current year OA Pubs

Propionibacteriaceae appear to have adapted to life on humans during the domestication of cattle. These microbial immigrants formed the genus Cutibacterium, and a descendent of those microbial trailblazers (C acnes) now dominates 25% of human skin. C acnes colonization of human skin requires the protein RoxP. Although all Cutibacteria encode this adaptation to life on humans, nothing like RoxP has been found in any other organism. In this study, we report an extensive assessment of 21 RoxP orthologs, which identified conserved molecular surfaces linked to heme-dependent oligomerization and low pH stability. Our investigation suggests how RoxP helps C acnes dominate …

Oculomics And Ai: The Eye As A Biomarker For Health Span, Joy Le Yi Wong, Rajendra S Apte, Et Al.

2020-Current year OA Pubs

As the world's population ages, the focus of healthcare is shifting from extending life span to promoting health span. There is an unmet need to identify sensitive and reliable markers of health span through more cost-effective and non-invasive methods, to enable early and effective intervention on modifiable aging factors. The eye offers a unique window into systemic health, providing direct visualization of the body's vascular and neural health. This review presents an overview of how various ocular structures can serve as biomarkers of health span-drawing on insights from ocular imaging, metabolomics, and proteomics, with evidence from basic science, animal models, …

Lost Before Forgetting: Objective Driving Metrics Track Navigation Deficits Tied To Preclinical Alzheimer's Disease, Yiqi Zhu, Ramkrishna K Singh, Semere Bekena, David C Brown, Chen Chen, Matthew Blake, Jean-François Trani, Ganesh M Babulal

2020-Current year OA Pubs

BACKGROUND AND OBJECTIVES: Navigation is a complex, multisensory process in which subtle changes may emerge before the onset of symptomatic Alzheimer's disease (AD). This study investigated whether navigation abilities were associated with amyloid and tau pathology in cognitively normal older adults.

RESEARCH DESIGN AND METHODS: Among 285 cognitively unimpaired older adults, navigation and objective driving behaviors were assessed using the self-reported Santa Barbara Sense of Direction Scale (SBSOD) and a datalogger, respectively. Amyloid and tau burden were quantified using PET-MRI 2 years post-initial driving data collection. Linear mixed-effects models were used to evaluate the associations between biomarker status and longitudinal …

Techmate:: Translating Gender Equality Research Into Actionable Practice For Computing Educators, Alina Berry, Susan Mckeever, Brenda Murphy, Sarah Jane Delany

Research Outputs: 2025-Present

The persistent underrepresentation of women in computing higher education remains a global challenge, with women comprising less than 20% of ICT specialists across the EU. While substantial research has identified effective interventions to support underrepresented groups, this evidence remains fragmented across academic publications, grey literature, and institutional reports. Educators seeking to implement gender-inclusive practices face significant barriers in identifying relevant initiatives, understanding implementation requirements, and accessing practical guidance suitable for their institutional contexts. This work presents TechMate, a fully operational (https://ascnet.ie/techmate/) web-based, open-access toolkit designed to bridge the gap between research evidence and practical implementation. The toolkit consolidates over 25 …

Mid-Infrared Spectroscopy And Machine Learning For Chlorogenic Acid Quantification In Coffee, Deborah Herdt, Felix Wühler, Thomas Kunz, Victoria Schiwek, Sarah Kühnemuth, Brian Gibson, Matthias Rädle

Research Outputs: 2025-Present

To predict chlorogenic acid (CGA) concentration in coffee during roasting, a machine learning algorithm was applied to mid-infrared (MIR) data. A total of 44 roasting samples between 140 and 220 °C, along with an unroasted control, were dry-heated in an eddy current roaster and subsequently ground and measured. CGA concentrations were predicted from MIR spectroscopy data using a multilayer perceptron (MLP) regressor and validated against a high-performance liquid chromatography with diode array detector reference. The algorithm performed spectral preprocessing and selected relevant wavenumber regions. The MLP-based model achieved a high coefficient of determination, outperforming classic peak evaluation, indicating that automated …

Smart Biosensing Nanomaterials For Alzheimer’S Disease: Advances In Design And Drug Delivery Strategies To Overcome The Blood–Brain Barrier, Manickam Rajkumar, Furong Tian, Bilal Javed, Bhupendra G. Prajapati, Paramasivam Deepak, Koyeli Girigoswami, Natchimuthu Karmegam

Research Outputs: 2025-Present

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by persistent memory impairment and complex molecular and cellular pathological changes in the brain. Current treatments, including acetylcholinesterase inhibitors and memantine, only help with symptoms for a short time and do not stop the disease from getting worse. This is mainly because these drugs do not reach the brain well and are quickly removed from the body. The blood–brain barrier (BBB) restricts the entry of most drugs into the central nervous system; therefore, new methods of drug delivery are needed. Nanotechnology-based drug delivery systems (NTDDS) are widely studied as a potential …

Development Of An Active Crosslinked Nanocomposite Film Based On Gelatin-Ethyl Cellulose, Trans-Cinnamaldehyde, And Silver Nanoparticles For The Preservation Of Sliced Meat, Elham Sarmast, Shiv Shankar, Stephane Salmieri, Sahra Amel Rahmouni, Monique Lacroix

Research Outputs: 2025-Present

This study aimed to develop a novel bioactive biobased packaging film combining gelatin (G) and ethyl cellulose (EC), cardanol and glycerol as plasticizers, trans-cinnamaldehyde (TCA) as a crosslinker/bioactive compound, and silver nanoparticles (AgNPs) as bioactive agents. The degree of crosslinking, mechanical and thermal properties, water solubility (WS), and water vapor permeability (WVP) of the films were analyzed. Molecular interactions within the film matrix were determined by FTIR spectroscopy. The G-EC film, in a 1:2 weight ratio, exhibited improved physicochemical properties compared to the pure G film, with a low WS (7.8%). The incorporation of TCA and AgNPs—to form bioactive nanocomposite …

Valorisation Of Barley Straw For Sustainable Nanocellulose Production Via Subcritical Alkaline Hydrolysis And Hdes-Assisted Processing, Dileswar Pradhan, Swarna Jaiswal, Brijesh K. Tiwari, Amit K. Jaiswal

Research Outputs: 2025-Present

This study investigates a sustainable and efficient approach to valorising barley straw by producing nanocellulose via an integrated subcritical alkaline hydrolysis and HDES-assisted processing pathway. Subcritical alkaline pretreatment under best processing conditions (150 bar, 200 °C, 125 min) enabled effective biomass fractionation, achieving average hemicellulose and lignin solubilisation of 57.72% and 82.69%, respectively. Subsequent purification of the pretreated solid fraction yielded cellulose fibres with an average cellulose yield of 41.97% and a purity of 87.87%. Nanocellulose was then obtained using a sequential HDES treatment followed by high-intensity ultrasound (HIUS), producing a sample (NC-BTW-3) in which 66% of particles exhibited diameters …

Multifunctional Nanomaterials Coupled With Ai-Based Optimization For Advanced Wastewater Treatment, Ananya Tiwari, Isha Dharsandia, Shreedhar Tiwari, Gajendra Singh Vishwakarma, Budhi Sagar Tiwari, Narendra Kumar, Amit K. Jaiswal

Research Outputs: 2025-Present

Conventional wastewater treatment performs reliably against routine contaminants but remains inconsistent for complex industrial effluents and for emerging pollutants such as pharmaceutical residues, per- and polyfluoroalkyl substances and micro/nano plastics. Engineered nanomaterials and artificial intelligence (AI)/machine learning (ML) have each been reviewed extensively, but predominantly in isolation. The present review is distinguished from existing reviews in three specific respects. First, the nanomaterial-AI interface is treated as the unit of analysis rather than the two fields being surveyed in parallel: AI-guided material selection, dosing and pH control, membrane fouling prediction, nano sensor-assisted monitoring and regeneration scheduling are examined together. Second, evidence …

United States V. Arthrex, Inc., 594 U.S. 1 (2021), Nina A. Mendelson, Rebecca S. Eisenberg

Book Chapters

United States v. Arthrex addressed a seemingly straightforward Appoint­ments Clause 1 challenge to the secretarially appointed administrative pat­ent judges (APJs) who serve on the Patent Trial and Appeal Board (PTAB). The challengers successfully argued that APJs exercised too much author­ity with too little supervision to qualify as "inferior" officers. Importantly, in Arthrex the U.S. Supreme Court also extended a recent string of invali­dations of legislative structures that had been aimed at enhancing agency independence. The Arthrex Court asserted the need for political control over agency adjudication decisions and did so, moreover, in an old depart­ment with a long administrative adjudication …

Optimizing Marketing Campaigns To Maximize The Response Rate For A Supermarket Using Machine Learning Techniques, Alia Almansoori

Theses

Supermarkets must improve their marketing tactics at a time of changing consumer behavior and increasing competition in the retail industry. Engaging the wide and sophisticated consumer base of today's supermarkets is difficult using traditional methods. This proposal presents a data-driven approach using cutting-edge machine learning methods to enhance supermarket marketing strategies. The main goal is to increase the response rate of marketing initiatives, which will improve consumer engagement and ultimately increase revenue. Additional primary objectives are customer segmentation and targeting, predictive modeling, personalization, ongoing performance monitoring, and ROI evaluation. The current problem centers around personalization and accuracy. Due to the …

The Impact Of Artificial Intelligence And Technology On Online Learning In The Higher Education Sector, Afra Alqemzi

Theses

The integration of Artificial Intelligence (AI) and technology into education has become an inseparable part of online education transforming the landscape of the higher education, which has provided a chance to experience flexible learning patterns according to personal needs, individualized and optimized instruction strategies and more effective and purposeful student involvement. Knowing how such technologies evolve in institutions with increasing implementation of AI-driven platforms is therefore critical to strategic and long-term planning. This paper aims at examining the effects of AI in the advancement of online learning in higher education, including the following aspects; improvements of outcomes, compliance with the …

Evaluating Datasets And Models For Offensive Language Identification, Skye Deson Morgan

Theses

Social media platforms enable people to easily communicate with one another, share ideas and express their opinions. Unfortunately, the anonymity provided by platforms such as Twitter and Facebook is more than enough to foster the spread of harmful content. Government agencies, as well as technology companies, are actively working towards finding better means of curbing offensive and objectionable content in social media and contributing to a more welcoming online environment. In this study, I first present a critical literature review on offensive language identification, exploring offensive language datasets and computational models using both machine learning and deep learning. Next, I …

Chronic Oral Cannabidiol Delays Seizure Onset And Reduces Seizure Burden In A Mouse Model Of Cln2 Disease, Joshua T. Dearborn, Keigo Takahashi, Nicholas R. Rensing, Michael Wong, Jonathan D. Cooper, Mark S. Sands

2020-Current year OA Pubs

A growing body of literature describes the anti-inflammatory, neuroprotective, and anti-epileptic properties of the cannabis sativa constituent cannabidiol, suggesting that it might play a useful role in the treatment of neurodegenerative diseases. Late infantile neuronal ceroid lipofuscinosis (CLN2 disease) is a rare pediatric neurodegenerative disorder resulting from an inherited dysfunction of the lysosome. CLN2 disease, and its representative animal models, display neuroimmune response, neuroinflammation, neurodegeneration, and epileptic seizures, and these symptoms are all touted as potential targets of cannabidiol therapeutic benefit. Here, we treated a valid model of CLN2 disease with long-term daily cannabidiol (300 mg/kg) from 1 month of …

A Designathon To Collaboratively Develop Sustainable Hiv Prevention Services For Youth With Community-Based Organizations In Nigeria, Titilola Gbaja-Biamila, Chiyere Arinze, Olufunto Olusanya, Temitope Ojo, Ross Brownson, Juliet Iwelunmor, Et Al.

2020-Current year OA Pubs

INTRODUCTION: The engagement of youth in the design of services that promote and increase the uptake of essential services to reduce HIV and other sexually transmitted infections is vital to sustaining these preventive services. The study objective is to identify strategies for sustaining HIV prevention services among Nigerian youth, in partnership with community-based organizations, through a crowdsourced open call and designathon in Nigeria.

MATERIALS AND METHODS: From February to March 2024, Nigerian youth (ages 14-24) submitted ideas to an open crowdsourcing call on how community-based organizations in Nigeria might sustain HIV self-testing and youth-friendly preventive services for at-risk youth. The …

Alzheimer's Disease Heterogeneity And Co-Pathologies: Defining Novel Targets, Biomarkers, Modalities, And Research Methodologies, Malú Gámez Tansey, Jorge J Llibre-Guerra, Suzanne E Schindler

2020-Current year OA Pubs

Alzheimer's disease (AD) is a biologically heterogeneous condition with vascular, proteinopathic, metabolic, and immune processes jointly shaping its clinical expression, trajectory of progression, and response to therapeutic intervention. Common AD co-pathologies such as cerebral amyloid angiopathy, Lewy body pathology, α-synuclein, and transactive response DNA-binding protein of 43 kDa (TDP-43)/limbic-predominant age-related TDP-43 encephalopathy are also increasingly connected with cognitive decline and therapeutic response. Significant advances in biomarkers, including seed amplification assays, proteomic signatures, and emerging positron emission tomography tracers bolster the field's understanding of a biological staging model and discovery of previously unrecognized co-pathologies. The Fall 2025 Alzheimer's Association Research Roundtable …