Digital Commons Network^™

Bioinformatic Identification And Analysis Of Shared Splicing Errors In Myotonic Dystrophy Type (Dm1) And Fuchs' Endothelial Corneal Dystrophy (Fecd), Carter I. Wilkins

Electronic Theses & Dissertations (2024 - present)

Myotonic dystrophy type 1 (DM1) is an autosomal dominant form of muscular dystrophy, and it is the most common form of adult-onset muscular dystrophy. The disease is the result of CTG trinucleotide repeats (TNR) in the 3’UTR of the dystrophia myotonica protein kinase (DMPK) gene. This produces toxic RNA hairpin structures by CUG repeat expansions that sequester proteins–most relevantly muscleblind-like 1 (MBNL)–that regulate alternative RNA splicing. The missplicing of a wide variety of genes results in the symptoms such as myotonia (rigidity of the muscles), atrophy, and cardiac failure.

Fuchs’ Endothelial Corneal Dystrophy (FECD) is characterized by progressive loss and …

Reviving Southern Divides: Multilevel Explorations Of Gentrification’S Role In School Resegregation In Tallahassee, Florida From 1999 – 2015, Ola U. Kalu

Electronic Theses & Dissertations (2024 - present)

This dissertation examines whether neighborhood gentrification in Tallahassee reshaped Title I elementary schools by improving academic outcomes, changing who enrolled, or both, from 1999 to 2015. Using Bronfenbrenner's Ecological Systems Model as a conceptual scaffold, the study situates schools within their neighborhood and district contexts across three nested analytical levels. A two-wave panel design using 2010 and 2015 school-year observations is linked to a 2000 Census baseline to connect school data with spatially weighted neighborhood change indicators. Mixed-effects multilevel models and fixed-effects robustness checks estimate the associations between neighborhood change indicators and two continuous dependent variables: standardized ELA achievement and …

Racial Bias In Collateral Report Of Adhd Symptom Endorsement, Teresa Mejia

Electronic Theses & Dissertations (2024 - present)

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most frequently diagnosed mental health condition among children in the United States. However, prevalence rates in the diagnosis and treatment of ADHD are unequal across populations. Specifically, the literature has demonstrated consistent variability in symptom endorsements and diagnosis dependent on a child’s demographic factors (i.e., race, gender, age). A diagnosis of ADHD requires that the diagnostic criteria be met in at least two aspects of a child's life, usually the school and home environments. As such, teacher reports are commonly used in the assessment of ADHD for children and adolescents. Given the challenges in obtaining …

The Communicative Constitution Of Resilience In Graduate-Student Parenthood: Ventriloqual Analysis, Intersectionality, And Sociomaterial Assemblages, Lin Lin

Electronic Theses & Dissertations (2024 - present)

Graduate education is often organized around norms of uninterrupted productivity, flexibility, and professional availability, making graduate study especially challenging for students who are simultaneously raising children. Although prior research has documented the structural barriers faced by graduate student parents (GSPs), less attention has been paid to how resilience is communicatively enacted within the intersection of academic work and family life. This dissertation examines how GSPs communicatively constitute resilience while navigating work-life disruptions. Drawing on Communication Theory of Resilience (CTR) and the communicative constitution of organizations (CCO) perspective, particularly ventriloqual analysis, this study explores how resilience emerges through interactions among human …

Perceptions Of Psilocybin-Assisted Psychotherapy And Standard Interventions For Nicotine Cessation, Philip Kamilar-Britt

Electronic Theses & Dissertations (2024 - present)

Clinical trials suggest potential therapeutic utility of psilocybin-assisted psychotherapy (PAP) for nicotine cessation. In response to promising outcomes, research into PAP for nicotine dependence is growing. However, attitudes towards PAP among the general public, especially daily nicotine users, remains understudied. To address this knowledge gap, we recruited daily nicotine users (N=534) to complete an anonymous online survey with questions on demographics, nicotine use, prior history with psychedelics, and attitudes towards PAP and standard interventions for nicotine cessation. As hypothesized, daily nicotine users were more familiar with standard interventions and rated them more favorably than PAP. Despite differences in treatment attitudes, …

From Written Curriculum To Classroom Practice: Teacher Supplementation In The Teaching Of American Slavery In Florida And New York, Matthew T. Maloof

Electronic Theses & Dissertations (2024 - present)

This study examined how K–12 public school teachers in Florida and New York perceived the adequacy of curriculum standards and instructional materials for teaching American slavery, how they responded when those materials were perceived as limited, and how the standards and materials aligned with Shuster’s (2018) Ten Key Concepts for Teaching American slavery. Using a qualitative multi-method design, the study combined qualitative survey research with document analysis. Teachers’ open-ended survey responses were analyzed through a Modified Grounded Theory approach, while curriculum standards and instructional materials were analyzed in relation to Shuster’s framework. The final sample included 41 teachers, including 20 …

Advancing Data Extraction Workflows For Single-Case Design Meta-Analysis Using Large Language Models, Yaosheng Lou

Electronic Theses & Dissertations (2024 - present)

Single-case experimental designs (SCEDs) are a form of longitudinal research that is particularly valuable for studying marginalized and underrepresented populations. Meta-analysis plays an essential role in synthesizing evidence across studies and enhancing the generalizability of findings. However, as interest in SCEDs grows and the evidence base expands, conducting meta-analyses has become increasingly labor-intensive and time-consuming. This dissertation addresses these challenges by examining the applicability of large language models (LLMs) for data extraction and meta-analytic dataset compilation in the context of SCED meta-analysis. Because LLM performance is influenced by model selection, prompt design, and the specific materials being extracted, this dissertation …

Psychometric Assessment Of The Facilitative Systemic Intervention Skills Rating System– Spanish Version, Sarah J. Crosky

Electronic Theses & Dissertations (2024 - present)

Despite the growing understanding of therapist factors in client outcomes, there remains limited understanding of the skills that distinguish effective family therapists. The aim of the present study was to assess the interrater reliabilities and factorial structure of a Spanish version of the Facilitative Systemic Intervention Skills (FSIS; Jones et al., 2023a), an observational rating system for evaluating the skillfulness of family therapists in delivering systemic interventions. The FSIS includes eight empirically and theoretically informed systemic therapy skills (Inclusiveness, Empathy for Relational Difficulties, Responsiveness to Safety Concerns, Collaborative Stance, Conceptualizing Family Problems Systemically, Responsiveness to Disparate Goals, Focus on Family …

Intergroup Relationship Attitudes Among Multicultural Adolescents In South Korea: Friendship, Dating, And Marriage, Jeewoo Shin

Electronic Theses & Dissertations (2024 - present)

This dissertation asks how multicultural adolescents in South Korea develop their attitudes toward crossing group boundaries in social and intimate life—whom they would accept as a close friend, a romantic partner, and a spouse—and what factors shape these attitudes. Korea’s immigrant population has grown more than seventyfold since 1990, largely through marriage migration, and the children of those unions are now reaching adulthood. Research on these adolescents has focused on how well they adjust, leaving open how they themselves come to view relationships across group lines.

Using eight annual waves of the Multicultural Adolescent Panel Study (N = 1,112), which …

Cognate Awareness Training For Novice L2 Learners: Orthographic And Phonological Routes To Vocabulary Learning, Jennifer M. Martin

Electronic Theses & Dissertations (2024 - present)

Within the study of cross-linguistic influence, research on cognate facilitation has consistently shown that proficient bilinguals process cognates (e.g., English “sock” and German “Socke”) more efficiently than non-cognates. However, less is known about how novice adult learners may benefit from these similarities during the earliest stages of second language acquisition or how instructional interventions might facilitate this process. This dissertation addressed this gap through experiments with English-speaking adults learning German. A series of experiments examined the effects of cross-linguistic similarity and explicit cognate awareness training on vocabulary acquisition. Experiment 1A found robust similarity effects in written recall and …

A Comprehensive Investigation Of Service Utilization In Innovative Models Of Hepatitis C Care And Treatment For Persons Who Inject Drugs In New York State, Amanda C. Sue

Electronic Theses & Dissertations (2024 - present)

Hepatitis C virus (HCV) is the most prevalent blood-borne infection in the United States and is primarily transmitted through the sharing of unsterilized drug injection equipment. With surges in opioid overdose deaths, there has been an increase in people diagnosed with HCV that can be attributed to persons who inject drugs (PWID) in the United States. PWID have therefore been identified as a priority population to achieve the goal of eliminating HCV as a public health threat. Despite the availability of safe and effective direct-acting antiviral (DAA) therapies that can cure people with HCV, uptake of HCV treatment in PWID …

Victimized And Criminalized: The Intertwined Narratives Of Trauma And Offending, Caitlin Maria Udas

Electronic Theses & Dissertations (2024 - present)

How do pathways between childhood victimization, drug use, and offending behavior vary for recordholders of different races and genders? Prior literature and theory indicates that there are distinct processes that can link childhood victimization to drug use and other offending behavior. These processes are rooted at least partially in experiences of racism/discrimination, placement relative to sociocultural power structures, and norms established over one’s childhood through peer and familial influences. However, less is known about how these differ by race, gender, and the intersection thereof. This dissertation examines the intersectional differences in narrative pathways that link childhood victimization, drug use, and …

Through Our Eyes: An Exploration Of Hope Among Opportunity Youth, Judith L. Fenlon

Electronic Theses & Dissertations (2024 - present)

Opportunity youth—young people aged 16–24 who are disconnected from both school and employment—experience significant barriers to successful transitions into adulthood. Existing research has largely focused on deficits, risk factors, and outcomes associated with disconnection, often overlooking the strengths, resilience, and aspirations of these young people. Hope has been identified as a critical factor associated with educational achievement, psychological well-being and future orientation; however, little research has explored how opportunity youth experience hope in the context of systemic inequities. The purpose of this study was to explore the lived experience of hope among low-income opportunity youth and to examine the factors …

Masses And The Gothic In The English Novel: 1700-1820, Szu Ying Chen

Electronic Theses & Dissertations (2024 - present)

This dissertation studies the eighteenth-century English novel and expands the understanding of realism by rereading realist novels through Gothic representations of the masses. The conventional understanding of realism is shaped by Ian Watt’s canonical concept of “formal realism” in The Rise of the Novel and Jürgen Habermas’s conception of the bourgeois public sphere. It identifies realism with a vision of civility grounded in the modern individual and bourgeois social reality. However, the masses and the Gothic challenge this conception of the novel’s realism by representing the social as constituted by collective agency, political violence, and struggles over power rather than …

From The Goodness Of Our Hearts: A Scoping Review Of Qualitative Literature On Altruism As A Reward Mechanism For Nursing, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Emily Horner, Norah L. Johnson

College of Nursing Faculty Research and Publications

Introduction

Altruism, the desire to help others, is a common motivation for choosing a career in nursing. Improved understanding of the role of altruism as a reward or motivation for currently-practicing nurses may inform future interventions to improve effort-reward balance among practicing nurses. Therefore, the purpose of this study was to collect, examine, and present literature on how altruism has been described as a reward mechanism or motivation for engaging in professional nursing.

Methods

This scoping review of literature used the Arksey & O’Malley method, PRISMA-ScR reporting checklist, and Rayyan review management platform. PubMed, Web of Science, and CINAHL were …

An Educational Intervention On Mutual Goal Setting For Hospital Nurses: A Mixed-Methods Study, Teresa Jerofke-Owen, Kristi Opper, Joseph Beiler, Maharaj Singh

College of Nursing Faculty Research and Publications

Background:

Including patients in mutual goal setting is one mechanism to personalize care delivery and improve patient outcomes.

Objective:

The purpose of this study was to examine the impact of a nurse educational intervention about mutual goal setting on nurse engagement and self-efficacy for goal setting and the nurse/patient experience of goal setting.

Methods:

During this explanatory, sequential mixed-methods study, nurse engagement in goal setting and goal quality was assessed through chart audits 1-month pre-intervention (n = 173) and 1 and 3-months (n = 144, n = 137) post-intervention. Nurse self-efficacy was measured with the Appraisal Inventory Tool. Patient experience …

Audiovisual Motion Onset Asynchrony As Expectation Violation: Effects On Memory And Liking In Media Contexts, Sijia Song

Electronic Theses & Dissertations (2024 - present)

This research presents the first systematic investigation of motion-onset asynchrony (MOA) as a form of audiovisual temporal incongruency grounded in contemporary spatial audio and extended reality (xR) systems. MOA—the delay between the onset of visual and auditory motion—was manipulated at three levels (0 s, 1.1 s, 3 s) to test its effects on cognitive (memory) and affective (liking) outcomes during short 2D animated video viewing. Guided by inverted-U models of expectation violation, it was hypothesized that moderate MOA would be associated with the highest memory performance and liking ratings and that liking would mediate MOA’s effects on memory. Across two …

Providers' Perceptions Of Barriers And Facilitators To Implementing Non-Pharmacological Treatment For Adults With Chronic Pain: A Meta-Synthesis, Mikhaela Mcfarlin

Electronic Theses & Dissertations (2024 - present)

Background. Chronic pain is a public health concern impacting approximately 20% of adults in the U.S. Nonpharmacological interventions are considered first-line treatments for patients with chronic pain, yet nonpharmacological interventions remain significantly underutilized. While previous research has explored barriers from the patient’s perspective, limited attention has been paid to providers’ experiences implementing these treatments. This qualitative meta-synthesis aimed to examine provider-perceived barriers and facilitators to implementing nonpharmacolgical treatments for adults with chronic pain. Methods. Independent reviewers conducted systematic searches across PubMed, PsycInfo, CINAHL, and ProQuest Dissertations using relevant (e.g., “mental health provider”, “nonpharmacological”) and applied inclusion criteria to …

Making Words Count: Computational Linguistics In Management Research, Joseph J. Simpson, Richard A. Hunt, David M. Townsend, Judy Rady, Elham Asgari, Mohammad Rady, Daniel J. Beal

International Business and Entrepreneurship Faculty Publications

In recent years, a rapidly growing number of management scholars are using computational linguistics (CL) to analyze vast corpora of naturally occurring organizational language. Yet the rapid adoption of CL methods has outpaced the development of shared standards for linking theoretical constructs, linguistic data, and computational measurement. We synthesize 353 articles published in leading management journals for 2013–2025, identifying four recurring challenges shaping the credibility of CL-based research: misalignment between constructs and textual corpora, unnecessary model complexity, the opacity of large language model workflows, and insufficient transparency in reporting. Building on these patterns, we develop four integrative design principles—construct-language fit, …

Making The Implicit Explicit: Leadership In Primary Care Dental Practice, Sally Hanks, Debby R.E. Cotton

Peninsula Dental School

Objectives: This paper reports on research aimed at understanding leadership activities in primary care dental practice, an under-explored area within the extant literature. Methods: The research employed a qualitative, exploratory paradigm, using Video Reflexive Ethnography (VRE) and Activity Theory (AT) to capture the lived experiences of seven participating dentists. Results: The research outlines the ways in which dentists demonstrate leadership skills in their daily work, identifying three interacting activity systems that define leadership in this setting: Patient Care (PC), Running the Surgery (RS), and Running the Practice (RP). Findings emphasise that leadership is directly related to patient care and is …

Educational Interventions To Prepare Undergraduate Students For Out-Of-Hours Practice As A Newly Qualified Doctor In The United Kingdom: A Scoping Review, Alex Gordon, Molly Parkinson, Rosanna Watts, Kamal El-Badawi, Erin Dawson, Rohan Chiktara, Lorna Burns, Nicola Brennan

Peninsula Dental School

Background: In the United Kingdom (UK), newly qualified doctors are routinely responsible for out-of-hours (OOH) care, often managing acutely unwell patients with limited supervision. Despite national recommendations encouraging OOH experience during medical school training, there is no formal curriculum for OOH practice. Objectives: This scoping review aimed to identify the range of educational interventions designed to prepare UK medical students for OOH clinical responsibilities and assess their reported effects on perceived and actual preparedness. Methods: Following Joanna Briggs Institute methodology, a systematic search of seven databases and grey literature sources was conducted. Eligible studies involved UK-based medical students and reported …

A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes

Peninsula Dental School

Introduction The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health interventions consider gender as part of their approach. The aim of this pilot study was to test the hypothesis that the oral microbiome and microenvironment change during female ageing and are thus worthy of further consideration both experimentally and clinically. Methods This observational pilot study retrospectively assessed women aged 18 to 89 years (n = 60) attending a UK primary care dental school facility for blood pressure …

Exploring The Acceptability Of Integrating Dietitians Into Primary Care Dental Services For Children, Lauren Hallewell, Raul Bescos, Zoe Brookes, Tracey Parkin, Robert Witton, Patricia Casas-Agustench

School of Health Professions

BACKGROUND: Dental caries is a common childhood non-communicable disease strongly associated with high sugar intake. Beyond oral health, a poor diet can affect children's growth, development, and overall well-being. While dietary advice is central to preventive dental care, some primary care dental clinics have introduced body mass index (BMI) assessments and further dietary advice to address wider nutritional concerns in children. However, these efforts are often constrained by limited nutrition training, time constraints and concerns about sensitivity. Integrating dietitians into primary dental care may help overcome these barriers by enhancing dietary guidance, supporting broader nutritional needs and facilitating structured BMI …

An Evidence Review Of Technology Enabled Social Care In The Uk: Report For Cornwall Health Determinants Research Collaboration, Sheena Asthana, Michael Loizou, Marius Varga, Oliver Beer, Rory Baxter, Kieran Green

School of Nursing and Midwifery

The Urgent Need for a Shift from Crisis Intervention to Prevention. As highlighted by the Chief Medical Officer, demographic ageing—particularly acute in coastal areas like Cornwall—necessitates a fundamental shift in care models to allow individuals to live as independently as possible. Currently, the potential of digital technologies to support this aim is not being realised. To maintain wellbeing and reduce demand on statutory services, the system must pivot from reactive crisis management to a greater focus on prevention. While technology can play a pivotal role, it will only succeed if integrated into interoperable, data-driven systems that facilitate early intervention and …

How Does Pre-Registration Child Specific Education Prepare Newly Qualified Nurses’ To Care For Children, Young People, And Their Families? An Empty Narrative Review, Matt Carey, Danielle Edge, Julie Blamires, Mandie Foster, Sarah Neill

School of Nursing and Midwifery

This narrative review investigates the influence of child-specific content within pre-registration nursing programs on newly qualified nurses’ perceptions of preparedness to care for children, young people, and their families. Despite international recognition of the specialised competencies required for pediatric nursing, the proportion and quality of child-focused education across Higher Education Institutions is not clear. The Population, Exposure, Outcome framework provided a comprehensive search strategy applied across eight databases to identify relevant studies that met the inclusion and exclusion criteria. Of 663 records identified, 451 were screened and 25 full texts wereassessed for eligibility by two reviewers. No studies met the …

Exploring The Views Of Children With Cerebral Palsy, Their Parents And Physiotherapists On Participating In A Feasibility Randomised Controlled Trial Testing An Exergaming Device: A Qualitative Study, Rachel Rapson, Jos M. Latour, Jonathan Marsden, Bernie Carter

School of Nursing and Midwifery

Background: This study aimed to understand the experiences and views of children with cerebral palsy, their parents and physiotherapists participating in the ACCEPT feasibility randomised controlled trial, which explored a 10-week physiotherapy intervention using an interactive gaming training device. Design: Qualitative methods included semi-structured interviews, e-diary and photographs. Nine parent–child dyads and three physiotherapists participated. Children were aged between 7 and 16 years; four had co-existing additional needs. Interviews were transcribed. Reflexive thematic analysis was used. Results: Five themes covered the breadth of participants’ experiences: (1) Fitting in therapy; (2) Motivation; (3) New opportunities; (4) Physiotherapists out of their comfort …

Understanding The Support And Information Needs Of Family Members After Acquired Brain Injury: A Systematic Review, Craig Andrews, Alyson Norman, Sue Jackson, Mark Holloway

School of Psychology

The aim of this systematic review was to (a) identify the specific information and support needs of family members caring for ABI survivors and (b) assess the effectiveness of current support systems and resources available. A comprehensive search of the literature was carried out, focusing on studies that were published between the years 2000 and 2025. Seventeen studies met the inclusion criteria. The review employed a narrative synthesis approach to collate findings across papers. The analysis identified five key themes: ABI Knowledge, The Strain of Unsupported Transitions, Emotional and Financial Cost, ABI Support Groups, and Supporting Social Connectedness. The findings …

Self-Guided Functional Imagery Training To Reduce Anxiety, Jackie Andrade, Stephanie Hartgen-Walker, Caroline Morgan, Ayan, Idil Aytekin, Khadijah Sekoni, Kardelen Sengul, Jonathan Rhodes

School of Psychology

Objectives: Many university students experience high anxiety but have limited access to effective interventions. We evaluated a novel digital intervention for anxiety based on functional imagery training (FIT), designed to help individuals identify the impacts of anxiety, set engagement goals, and strengthen motivation for change. Functional Imagery for Keeping Anxiety low (FIKA) uses speak-aloud tasks, journalling, empathic questions, and personalised guided imagery for a person-centred approach. It builds motivation for engagement goals over safety goals through development and practice of vivid and emotionally laden multisensory imagery. Design: Study 1 used semi-structured interviews and thematic analysis to explore user experiences of …

Dampened Social Motivation In Dysphoria: The Role Of Negative Social Expectancies And Internal Causal Attribution Style, Julie L Ji, Nilly Mor, Colin Macleod

School of Psychology

Dysphoria is associated with dampening of social interaction intention, but the cognitive mechanisms that underpin this relationship are under-investigated. This study tested the hypothesis that heightened negative social expectancies mediate the association between dysphoria and dampened social motivation. Additionally, it tested the hypothesis that the association between dysphoria and negative social expectancies is mediated by an attribution style bias that attributes negative, but not positive, outcomes to internal causes. University students (N = 271) with varied levels of dysphoria read vignettes describing hypothetical situations where they initiate a social interaction that results in positive or negative outcomes. Participants rated their …

Training Healthcare Professionals To Deliver A Group-Based Intervention For People Living With Severe Obesity: Lessons From The Progroup Feasibility Trial, Shokraneh Moghadam, Mark Tarrant, Lily Hawkins, Dawn Swancutt, Rod Sheaff, Laura Hollands, Raff Calitri, Jonathan Pinkney, Jenny Lloyd

School of Psychology

Introduction: Group-based programmes are increasingly adopted to support people living with obesity, as they have the potential to reduce staff time and costs and enhance motivation and capability for behaviour change. Group-based programmes could also provide members with opportunities to form meaningful social connections. As such, training should equip healthcare professionals to deliver group interventions successfully and be accessible and feasible for them to complete. This study presents how mixed-methods process evaluation data from the feasibility randomised controlled trial of PROGROUP (a group-based weight management intervention for people living with severe obesity) informed optimisation of the PROGROUP training programme. Methods: …