Digital Commons Network^™

Multi-Agent Reinforcement Learning Driven Package Pdn Design Automation, Haran Manoharan, Chulsoon Hwang

Electrical and Computer Engineering Faculty Research & Creative Works

The design of package-level power delivery networks (PDNs) has become increasingly challenging as modern high-performance systems demand higher currents. Existing PDN design flows treat ball map assignment, stackup selection, and power plane routing as separate, largely manual steps, leading to long iteration times and limited scalability. This work proposes a unified and automated package PDN design framework based on multi-agent reinforcement learning (MARL). Each power domain is modeled as an agent, with specialized agents responsible for ball map assignment, routing layer selection, and power plane synthesis. A central controller coordinates agent decisions using a global reward that captures electrical and …

Deep Learning Based High-Resolution Electromagnetic Inversion Imaging Using Deep Convolutional Double-Module Structure, He Ming Yao, Shiji Song, Lijun Jiang, Michael Ng

Electrical and Computer Engineering Faculty Research & Creative Works

In this paper, a novel deep learning (DL) approach has been proposed to realize high-resolution electromagnetic (EM) inversion imaging. The newly proposed approach is based on the deep convolutional double-module structure (DCDMS), consisting of the pixel-interpolating module and the corresponding quality-improving module. While the pixel-interpolating module roughly increases the 'resolution' of the initial input, the following quality-improving module realizes quantitative EM imaging in high resolution. The input of the proposed DCDMS adopts the mixed input scheme, consisting of the received EM scattered field and the initial reconstruction in much low resolution computed from Gauss-Newton method. The output of the proposed …

Event-Based Predefined-Time Synchronization For Complex Networks With Deception Attacks: An Asynchronously Intermittent Strategy, Lei Xue, Jiong Yu, Haoyu Zhou, Yongbao Wu, Jian Liu, Donald C. Wunsch

Electrical and Computer Engineering Faculty Research & Creative Works

This article studies the practical predefined-time synchronization (PPTS) for complex networks (CNs) under deception attacks based on the asynchronously intermittent event-triggered control (AIE-TC). Notably, AIE-TC effectively integrates the advantages of asynchronously intermittent control (AIC) and event-triggered control, where AIC provides each subsystem node with independent control and rest intervals. Besides, all synchronization errors of the CNs converge to an adjustable neighborhood within the predefined time by designing a bounded time-varying function into the controller. Moreover, this article considers that the transmission network is subjected to stochastic deception attacks modeled by a Markov process, which captures the state-driven dynamic transition characteristics …

Effect Of Sample Properties On Short-Circuited Waveguide Measurements For Materials Characterization, Alexander Hook, Jared Sinkey, Kristen M. Donnell

Electrical and Computer Engineering Faculty Research & Creative Works

Microwave materials characterization measurements can be performed using a number of well-established approaches. One such approach, the filled transmission line approach featuring a short-circuited rectangular waveguide (SC-RWG) sample holder, is known to have sample placement restrictions related to measurement viability. This work focuses on this approach and addresses the measurement restrictions within the context of sample length and dielectric properties. The complex reflection properties, S11, of a sample placed in a SC-RWG sample holder are studied to quantitively define when a sample must be offset from the SC-end. The impact of the sample holder is also studied from a measurement …

Femtosecond-Laser-Inscribed Cladding Fiber Bragg Gratings: Architectures, Design Trade-Offs And Future Sensing Opportunities, Koustav Dey, Rex E. Gerald, Chen Zhu, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

Femtosecond (fs) laser inscription enables fiber Bragg gratings (FBGs) to be positioned beyond the fiber core, including within the cladding, thereby expanding control over modal interactions and directional sensing. These cladding fiber Bragg gratings (CLFBGs) extend FBG functionality through interactions with core, cladding, and evanescent fields. Their operation does not involve fundamentally different grating physics; rather, core-mode, cladding-mode, and coupled-mode responses depend on power distribution, modal overlap with the laser-inscribed refractive-index modulation (RIM), grating position, fiber geometry, modal excitation, and interrogation configuration. This Perspective reviews advances in CLFBG fabrication, optical characteristics, sensing mechanisms, and applications. Cladding-waveguide-assisted, evanescent-field-coupled, and direct cladding-mode-excitation …

[Introduction To] Shakers At The Center : Manifesting Spirits & Spectacles In Nineteenth-Century America, Douglas L. Winiarski

Bookshelf

Edited by Douglas WIniarski.

"Exploring the theological, social, and cultural dimensions of one of America’s most ambitious prophetic movements

The Shakers’ Era of Manifestations ranks among the most astounding events in American religious history. During the 1840s, members of the United Society of Believers in Christ’s Second Appearing embarked on an audacious project of receiving visions, revelations, and other manifestations from the spirit world and convincing both themselves and the world’s people of their reality. Gifted Shakers known as “instruments” surrendered their bodies to possessing spirits and celestial beings who, in turn, provided the Believers with an unimaginable number of …

Organ Chips And Translational Research: Identifying And Examining New Ethical Issues, Melanie Jeske

Center for Medical Ethics and Health Policy Staff Publications

Organ chips, also known as organ-on-a-chip devices, tissue chips, or microphysiological systems, have emerged over the last decade as a promising translational technology amidst growing concern about the translational crisis between laboratory research and patient bedside. Pointing to high rates of failure between nonhuman animal models and safety and efficacy in humans, organ chips and similar new approach methods have attracted substantial public and private investment. As human-cell-based alternatives to animal models, organ chips promise more predictive, efficient, and ethical platforms for pharmaceutical and toxicity testing. Engineered cultivation systems that enable cells to assemble into tissue-like structures (e.g. kidney, brain, …

Anything But Endo: Diagnostic Buck-Passing In Endometriosis Diagnosis, Rita Dexter, Megan Kitts, Heather Welty, Melanie Jeske

Center for Medical Ethics and Health Policy Staff Publications

People living with endometriosis, a disease in which tissue similar to the lining of the uterus grows elsewhere in the body, often experience prolonged diagnostic journeys because of symptom variability, normalisation of period pain and other symptoms, and lack of awareness of the condition. In this article, we analyse the endometriosis diagnostic journey through the lens of epistemic injustice. Drawing on in-depth interviews with 52 people living with endometriosis in the United States, we introduce the concept of diagnostic buck-passing to characterise the phenomenon wherein individuals who seek treatment for their symptoms end up stuck in a cycle of seeing …

Can I Get A Witness? The Ethical Dimensions Of Family Presence In Patient Suffering, Jennifer Blumenthal-Barby, Trevor M Bibler, Holland Kaplan, Adam Omelianchuk, Joanna Smolenski

Center for Medical Ethics and Health Policy Staff Publications

For patients who are suffering, the bedside presence of a family member can provide comfort, and many people hold that there is moral value in being present with a conscious, suffering patient. Yet what is the moral significance of the absence of family members when a patient is minimally conscious or unconscious and not aware of their absence? Clinicians are often troubled when family members and surrogate decision-makers who are able to spend a significant amount of time at an unconscious, seriously ill patient's bedside do not do so. Clinicians feel frustrated that they must bear the burden of witnessing …

Toward Ethical Provenance Tracking: The Ga4gh Model Data Access Agreement (Daa), Alexander Bernier, Bartha Maria Knoppers, Jonathan Lawson, Robyn Mcdougall, Maili Raven-Adams, Vasiliki Rahimzadeh

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Standardizing contractual clauses that govern data access enables research institutions to responsibly steward genomic and related health data while enabling its efficient downstream reuse.

Methods: We describe a document analysis study using both qualitative and comparative law analytical approaches to identify the most common categories of clauses from 29 different data access agreements used by human biomedical research consortia globally. We furthermore characterized the legal positions and standard practices for each common element of the agreement and synthesized across them to develop model clauses. A total of 3 discussion sessions were organized virtually to refine the clauses among members …

Spatial Evolution In Temporal Dynamics Of Hemodynamic Response Function In Human Superior Colliculi With Ultra-High-Resolution Mri At 9.4t, Nooshin J Fesharaki, Artemy Vinogradov, David Ress, Jung Hwan Kim

Faculty, Staff and Student Publications

The superior colliculus (SC) plays a crucial role in multisensory integration, visual information processing, saccadic target selection, visual selective attention, and decision making. In particular, the SC has a key role in oculomotor coordination, following a rostro-caudal organization. The rostral SC, which corresponds to foveal representation, is linked to fixation, microsaccades, smooth pursuit, and vergence adjustments. In contrast, the caudal SC, representing more peripheral visual field, is associated with the large gaze shifts (saccades). However, evidence regarding whether this functional gradient is preserved in the human SC remains limited. In this study, we employed a sequence-following visual-motor task to specifically …

Polyfluoroalkyl Substances And Altered Glucose Homeostasis In Adolescents Following Bariatric Surgery, Elizabeth Costello, Brittney O Baumert, Zhenjiang Li, Vishal Midya, Shudi Pan, Justin R Ryder, Thomas H Inge, Todd M Jenkins, Stephanie Sisley, Stavra A Xanthakos, Anita Courcoulas, Douglas I Walker, Nikos Stratakis, Damaskini Valvi, Scott M Bartell, Angela L Slitt, Rohit Kohli, Sarah Rock, Michele A La Merrill, Sandrah P Eckel, Max T Aung, Rob Mcconnell, David V Conti, Lida Chatzi

Children’s Nutrition Research Center Staff Publications

Objectives: Bariatric surgery is an effective treatment for severe obesity and associated metabolic comorbidities. Exposure to polyfluoroalkyl substance (PFAS) before bariatric surgery may attenuate improvements in glucose metabolism and explain some of the heterogeneity in post-surgery outcomes.

Design: This is an observational cohort study.

Methods: Adolescents (n = 186) enrolled in the Teen-Longitudinal Assessment of Bariatric Surgery study were included. Eight-PFAS congeners were measured in plasma before surgery. Linear and logistic regressions were used to examine cross-sectional associations between log2-transformed PFAS (ng/mL) and fasting glucose, insulin, hemoglobin A1c (HbA1c), and homeostatic model assessment for insulin resistance (HOMA-IR). Linear mixed …

Corticotropin-Releasing Factor Neurons In The Bed Nucleus Of The Stria Terminalis Modulate Avoidance Behaviors And Feeding, Juan Manuel Romero, Shae-Marie Stafford-Trujillo, Mitzy Mendoza, Pey-Shyuan Chin, Snigdha Srivastava, Mikhail Kochukov, Qingchun Tong, Benjamin Russell Arenkiel

The Brown Foundation: Institute of Molecular Medicine

Introduction: Animals rely on defensive avoidance of exposed or potentially threatening environments as a fundamental survival strategy, often expressing this behavior as thigmotaxis, or a preference for the periphery of an open space. However, researchers still do not understand how neural circuits coordinate avoidance behavior with competing physiological drives such as feeding. In this study, we investigate how corticotropin-releasing factor (CRF)-expressing neurons in the bed nucleus of the stria terminalis (BNST) integrate environmental avoidance and feeding behavior.

Methods: We used adult male and female mice and applied fiber photometry to monitor BNST CRF neuronal activity in vivo. We performed both …

Cerebellar Motor And Non-Motor Contributions To Dystonia Pathophysiology And Treatment, Linda H Kim, Cheryl Brandenburg, Roy V Sillitoe

Duncan NRI Faculty and Staff Publications

Dystonia is a complex neurological disorder characterized by sustained or intermittent abnormal movements and/or postures. However, dystonia's non-motor symptoms, particularly the sleep disturbances, are critical yet underexplored concerns that affect all ages. Here, we synthesize current knowledge on the motor and non-motor domains of dystonia, emphasizing the functional interconnections and plasticity within cerebellar motor, cognitive, and sleep-associated circuits to motivate more comprehensive and effective treatments that improve overall quality of life.

Borderplex Business Barometer, Volume 10, Number 1, Thomas M. Fullerton Jr., Steven L. Fullerton

Border Region Modeling Project

No abstract provided.

Borderplex Business Barometer, Volume 10, Number 3, Thomas M. Fullerton Jr., Steven L. Fullerton

Border Region Modeling Project

No abstract provided.

El Paso Business Cycle Downturn Analysis: 1991 – 2025, Steven L. Fullerton, Thomas M. Fullerton Jr.

Border Region Modeling Project

Recession indicator research for the United States and other national economies has accelerated since 2019. Because of relative ease of implementation, these indices show much promise and expand the business cycle toolkit for applied economists, policy analysts, and business planners. From a regional perspective, a potentially attractive feature of these indices is fairly minimal data requirements. This study extends this branch of the business cycle literature into the realm of regional economics. An application of the framework is developed for El Paso, Texas, USA. That metropolitan economy is a natural candidate for this type of exploratory analysis because of the …

Physics-Constrained Generative Adversarial Networks For Dimensionality Reduction In Optimization, Samuel Sisk, Xiaosong Du

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Electric vertical takeoff and landing (eVTOL) aircraft make a unique form of urban air mobility due to their low noise, zero emission, and precision control. To maximize efficiency, high-fidelity simulation-based multidisciplinary design optimization discovers the optimal balance among subsystems within an eVTOL. However, conventional multidisciplinary design optimization is computationally intensive due to excessive high-fidelity model evaluations. Moreover, complex nonlinear constraints deteriorate optimization efficiency and convergence. While surrogate models enable efficient design optimization, surrogate modeling suffers in large-scale applications and surrogate-based optimization still has to deal with nonlinear constraints. To address these challenges, the authors' previous work proposed physics-constrained generative adversarial …

Optimal Takeoff Trajectory Prediction Of Electric Drones Based On A Fully Automated Optimal Experimental Design Method, Jiachen Wang, Dheeraj Paramkusham, Xiaosong Du

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Electric vertical takeoff and landing (eVTOL) aircraft is attracting great interest as a viable solution to promote urban aerial mobility with promising flexibility as well as emission reductions. However, the low specific energy of the current battery is still a strong constraint on the range and endurance of eVTOL flights, especially considering the significant power demands during the takeoff process. Engineering design optimization permits promising solutions for the minimum takeoff energy consumption but can be computationally intensive due to iteratively evaluating simulation models. Surrogate-based design optimization is efficient but still relies on optimization iterations which prohibit real-time decision-making. To fill …

Atomized Oxidative Polymerization As A 3d Printing Platform For Binder-Free, Bulk Conductive Polymer Architectures, Tazdik Patwary Plateau, Hiep Pham, Jonghyun Park

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Translating the ultrahigh intrinsic conductivity of conjugated polymers into bulk 3D architectures remains a formidable challenge due to the fundamental dichotomy between rheological printability and electronic purity. Existing strategies necessitate a compromise: solution-processing requires insulating binders that degrade charge transport, while binder-free vapor-phase polymerization (VPP) is kinetically confined to surface-limited thin films by diffusion constraints. Here, we introduce atomized oxidative polymerization (AOP), a manufacturing paradigm that overcomes these kinetic barriers via active, layer-by-layer monomer atomization. This approach ensures stoichiometric reaction conditions throughout the printed volume, driving a structural transition toward highly conductive quinoid-dominant chains with enhanced π-π stacking. The resulting …

Anisotropic Second-Harmonic Ince-Gaussian Beam Generation Using Nbobr2 Holograms, Jayanta Deka, Xiaodong Yang, Jie Gao

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Ince-Gaussian (IG) modes are a complete and orthogonal set of solutions to the paraxial wave equation in elliptic coordinates representing a continuous transition between Hermite-Gaussian modes and Laguerre-Gaussian modes. Chip-scale platforms to generate IG beams have great significance for various applications, including optical trapping and micromanipulation of particles, optical communication, and quantum optics. On the other hand, materials with high optical anisotropy are crucial for building polarization-sensitive optical devices. In this context, niobium oxide dihalides are a new class of ferroelectric materials exhibiting strong, tailorable, and highly anisotropic second-harmonic generation responses. Here, we report the generation of highly anisotropic second-harmonic …

Supersonic Wind Tunnel Free Stream Turbulence Characterization Using 2-Point Focused Laser Differential Interferometry, Joseph Villarreal, Joshua Gary, Davide Vigano

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Non-intrusive laser-based diagnostics, such as Two-Point Focused Laser Differential Interfer-ometry (2-FLDI), play a crucial role in modern aerodynamic research by enabling simultaneous measurements of density and velocity in compressible flows. A 2-FLDI system has been developed and implemented for the Missouri S&T Supersonic Wind Tunnel to characterize free stream turbulence fluctuations and free stream convective velocity. Design choices that enabled the 2-FLDI to overcome low turbulence to measure free stream velocity are detailed. The free stream velocity measurements are validated against previous particle image velocimetry data, showing good agreement. Analysis of normalized velocities and density-based turbulence intensities found that the …

2-Point Focused Laser Differential Interferometry Measurements Of A Parallel Jet In Supersonic Flow, Joshua Gary, Joseph Villarreal, Davide Vigano

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Turbulence in compressible flows plays a central role in applications such as air-fuel mixing in supersonic combustors and is significantly more complex than incompressible turbulence due to the presence of fluctuating thermodynamic quantities. As such, models like the Strong Reynolds Analogy (SRA) are used to relate these quantities. However, SRA validity has been examined primarily in boundary-layer flows. In this work, a newly developed Two-Point Focused Laser Differential Interferometry (2-FLDI) system is implemented in a two-dimensional parallel supersonic jet. The diagnostic is described in detail, including optical alignment procedures, calibration methods, and data analysis techniques. Measurements acquired at multiple streamwise …

Polysemicolon; Novice Programmers And Java Keywords, Briana C. Bettin

Michigan Tech Publications

Most industrial programming languages leverage the English language for reserved keywords – words which a program compiler recognizes as specific execution commands. The divide between expert and novice programmers showcases an intriguing middle-ground by which the polysemy of many keywords becomes revealed. This essay explores a sampling of the multitude of keyword interpretations that a novice programmer may derive from the Java language’s syntactic style and keywords specifically, and how the polysemy of both “English” and “code” meanings to these terms affects the novice-expert programmer transition.The transition from novice to expert, and the mapping of the career of metaphor to …

Large Aerosol Particles Favor Haze Conditions Through Limitations On Water Budget And Activation Kinetics, Hamed F. Sadi, Ernie Lewis, Kadja Flore Gali, Fan Yang, Jesse Anderson, Suryadev Pratap Singh, Jae Min Yeom, Will Cantrell, Raymond Shaw

Michigan Tech Publications

Experiments in the Pi Convection‐Cloud Chamber conducted by systematically changing the diameter of injected dry aerosol particles while holding the temperature difference constant demonstrate that dry diameter strongly influences the onset of haze‐dominated conditions. Two factors contribute: the system becomes water‐limited, resulting in reduction of supersaturation by growing aerosol particles to the activation diameter; and the activation process becomes kinetically limited. Dry aerosol diameter exerts a strong influence on activation time, with a power‐law exponent of 9/2. Kinetically limited activation occurs when the ratio of the activation and droplet residence times is greater than unity. The findings demonstrate that a …

Equity And Justice In Water Pricing And The Effects On Water Distribution System Management, Brian Barkdoll

Michigan Tech Publications

Equity regarding access to potable water is paramount. Municipal Water Distribution Systems supply potable water to users and are essential to public health. To find the optimal price of water to maximize utility revenue and allow changes to the system components for capital and maintenance expenditures, network modeling was performed for 15 real MDWSs. A new power-law price-usage elasticity curve, entitled the Power Law Elasticity Function (PLEF), was used that allowed for various users, both high- and low-income, and a non-discretionary level of usage. It was found that: (1) the maximum profit was obtained when the price was approximately 0.8 …

Case Series Of Nizon-Isidor Syndrome By Heterozygous Variants In Med12l With Further Evidence Of Mitotic Instability In One Case With Diploid-Triploid Mosaicism, Russell Stewart, Kimberly M Ezell, Deanna S Bell, Brian Corner, Ashley Mcminn, Joy D Cogan, Rizwan Hamid, Lynette Rives, John A Phillips, Nina Paddu, Gitanjali Srivastava, Ronit Marom, Farah A Ladha, Claudia Soler-Alfonso, Rachel Franciskovich, Mary Koziura, Sumit Pruthi, Gabriele Richard, Christina B Sheedy, Undiagnosed Diseases Network, Thomas Cassini

Faculty, Staff and Students Publications

Nizon-Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7-year-old female who presented with developmental delay, right-leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin pigmentation, sectoral iris hypopigmentation, dysphagia, periventricular nodular heterotopia, seizures, morbid obesity, and a pelvic kidney. Genome sequencing (GS) revealed a MED12L variant, NM_053002.5:c.3559+2T>G. Both computational models and transcriptomic analysis confirmed that this variant induced splice loss of MED12L exon 25. Probands 2 and 3 presented with overlapping phenotypes of developmental delay; sequencing …