Digital Commons Network^™

Seizure Susceptibility And Morphological Analysis Of A Missense Mutation In Hcfc1a Protein, Jose Manuel Fabela

Open Access Theses & Dissertations

Missense mutations in the HCFC1 gene cause methymalonic acidemia with homocystinuria cblX type (MIM#309541). cblX is an X-linked disorder that is associated with multiple phenotypes such as metabolic defects, failure to thrive, intractable epilepsy, facial dysmorphia, movement disorders, and intellectual disability. The mechanisms underlying these phenotypes are not completely understood. Here we used a zebrafish germline mutant allele (hcfc1aco64/co64) to study seizure susceptibility and adult brain structural malformations. Previous studies have established neural progenitor cell defects and hypoactive mechanistic target of rapamycin (mTOR) in this allele. Given the known role of mTOR in seizure phenotypes, we hypothesized that missense mutation …

Prevalence Of Type 2 Diabetes Risk Factors Among Landscaping Workers In El Paso, Texas, Valeria Fontes

Open Access Theses & Dissertations

Type 2 diabetes mellitus (T2DM) is a significant public health challenge worldwide, yet little is known about the prevalence of diabetes risk factors among landscaping workers, an understudied occupational group. The purpose of this pilot study was to estimate the prevalence of type 2 diabetes risk factors among landscaping workers in El Paso, Texas. A descriptive cross-sectional study was conducted using a convenience sample of 20 landscaping workers. Participants completed a structured questionnaire and underwent anthropometric measurements, blood pressure assessment, point-of-care lipid and glucose testing, and vitamin D screening. Sixteen type 2 diabetes risk factors were assessed across seven domains: …

Behavioral And Dietary Associations Of Vitamin D Deficiency Among Landscaping Workers: An Analytical Cross-Sectional Study In El Paso, Texas., Cristela Anahi Avila

Open Access Theses & Dissertations

Background: Vitamin D deficiency is a persistent public health concern, even among outdoor workers who receive substantial sunlight exposure. Landscaping workers may still be at risk because sun-protective clothing, early work hours, behavioral practices, and low dietary intake can reduce effective vitamin D synthesis. Purpose: This pilot study examined dietary vitamin D intake, sun exposure behaviors, and serum 25-hydroxyvitamin D status among male landscaping workers in El Paso, Texas, to identify behavioral and nutritional factors associated with deficiency. Methods: Twenty participants completed a culturally adapted food frequency questionnaire and behavioral assessment and underwent capillary point-of-care testing for serum 25(OH)D. Descriptive …

Graduate School Blog - August 2026, Cynthia Haynes

UofM Grad School Blog

This issue welcomes our newest graduate students and highlights Fall 2026 Graduate Student Orientation, featuring insights on navigating graduate school and connecting with the UofM community. We also spotlight Dr. Deborah Tollefsen’s latest installment of the Removing Barriers to Graduate Student Success series, upcoming graduate student events and webinars, opportunities to get involved through the Graduate Student Association and Graduate School Ambassador program, and important academic dates.

The Effect Of Childcare On Female Labor Supply And Child Development In Low And Middle Income Countries, Serena Goldberg, Costas Meghir

Discussion Papers

Childcare services can offer an opportunity for women to develop their careers and increase household income. At the same time, it can affect the development of children, depending on the quality of care. We first develop a collective model of the household as a conceptual framework to show how improving the availability of childcare can affect mothers’ labor market opportunities and earnings and how it can affect child development. We then review the literature on the effects of childcare on the employment and earnings of women and on child development. Childcare can increase mothers’ employment. However, limited work opportunities or …

Ssw 701.50: Social Welfare Policy, Ian G. Williams

Open Educational Resources

This syllabus is an Open Educational Resources (OER) remixed version of SSW 701.50: Social Welfare Policy, which is taught at the Silberman School of Social Work at Hunter College. This version updated the content and integrated additional OER materials, as part of the Summer 2026 cohort of The Open Knowledge Fellowship at the Mina Rees Library. It is a Zero-Textbook (ZTC) cost course and integrates materials from a range of academic disciplines. Official course description is as follows:

"This foundation course furnishes you with the orienting knowledge and skills needed to examine social welfare policies and to understand their relevance …

2026 Deerfield Fair 4-H Exhibit Building Premium Book, Extension

UNH Cooperative Extension

No abstract provided.

Carroll County Extension Update August 2026, Mikayla Cerney

UNH Cooperative Extension

No abstract provided.

2026 Deerfield Fair 4-H Animal Premium Book, Extension

UNH Cooperative Extension

No abstract provided.

Disrupting The Bonded Economy Of Sex Buying, Sex Trafficking, And Organised Crime Through Policy Change, Dellene Clark

Dignity: A Journal of Analysis of Exploitation and Violence

Emerging criminological research underscores how the economic drivers of trafficking for sexual exploitation reinforce organised criminal markets while reproducing the structural vulnerabilities of those in prostitution. Using South Africa as a case study, this article argues that evidence-based legislative reform is necessary to confront the systemic conditions that enable exploitation. It contends that achieving substantive equality requires recognising the criminogenic role of sex‑buyer demand in sustaining trafficking pipelines and criminal profitability. The Swedish/Nordic demand‑reduction model illustrates how asymmetrical criminalisation can suppress demand, reduce reliance on trafficked persons, and diminish the financial incentives that underpin organised crime. Such an approach reorients …

Exploring The Associations Between Dietary Nitrate And Nitrite Intake And Markers Of Self-Reported Periodontal Disease In The Uk Biobank Cohort, Shatha S. Alhulaefi, Anthony Watson, Kirsten Brandt, Sheena E. Ramsay, Nicholas S. Jakubovics, Alex Griffiths, Jamie Matu, Mario Siervo, Benjamin H, Parmenter, Liezhou Zhong, Jonathan Hodgson, Catherine P. Bondonno, Nicola P. Bondonno, Oliver M. Shannon

Research outputs 2022 to 2026

Purpose: Periodontal disease, an inflammatory condition affecting the tissue surrounding the teeth, has been associated with various systemic health issues. Dietary nitrate and nitrite are found in a range of plant and animal foods and, depending upon source, have been linked with both positive and negative health effects, including improved oral health with plant sources. This study aimed to investigate the associations between source-dependent (plant- and animal-sourced) nitrate and nitrite intake and odds of periodontal disease. Methods: We explored cross-sectional and longitudinal associations between tertiles of source-dependent nitrate and nitrite intake and the odds of periodontal disease using multivariable logistic …

Source-Specific Nitrate And Nitrite Intake And Bladder Cancer: Findings From The Danish Diet, Cancer And Health Cohort, Dorit W. Erichsen, Cecilie Kyrø, Jörg Schullehner, Susanne Rosthøj, Catherine P. Bondonno, Liezhou Zhong, Ole Raaschou-Nielsen, Pratik Pokharel, Torben Sigsgaard, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Christina Dahl, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno

Research outputs 2022 to 2026

Introduction Nitrate and nitrite, present in ground and drinking water, as well as foods, may contribute to bladder cancer through the formation of carcinogenic N -nitrosamines. However, risk likely depends on both the source and endogenous nitrosating factors. Methods Among participants of the Danish Diet, Cancer, and Health Cohort (N = 54,610) with no history of cancer, source-specific nitrate and nitrite intakes (drinking water, plant sources, naturally occurring animal sources, and additive-permitted meat sources) were estimated from national water monitoring data and food frequency questionnaires using food databases. Bladder cancer cases were ascertained through the Danish Cancer Registry. Multivariable-adjusted Cox …

Remote Assessment And Management Of Physical Function In Older Adults (Ramp): An International Expert Delphi Process, Jack Dalla Via, Hurst, Elsa Dent, Jackson J. Fyfe, Paul Jansons, Eleanor J. Hayes, Marc Sim, Mylene Aubertin-Leheudre, Alex Barreto De Lima, Lucimere Bohn, Sabine Britting, Fanny Buckinx, Gavin Connolly, Lora Giangregorio, Duarte Henriques-Neto, Jennifer R.A. Jones, Robert Kob, Suzanne N. Morin, Girish N, Lucas B.R. Orssatto, Maria Pearson, Daniel Pinto, Esmee M. Reijnierse, Catherine M. Said, Mohamed Salem, Gary Skinner

Research outputs 2022 to 2026

Background: Remote methods may help older adults improve their physical function, but understanding the perspectives of experts who deliver this care is critical. This modified Delphi process aimed to develop expert consensus on effectiveness, feasibility and implementation of remote assessment and management of physical function in older adults. Methods: This online Delphi process included experts involved in supporting older adults to maintain or improve their health. The Round 1 survey presented 33 Delphi statements assessed using an 11-point Likert scale (0–10; ≥7 indicated agreement). Statements with strong (≥80 %), moderate (50–<80 %) and low (<50 %) agreement were accepted, revised, or rejected, respectively. Revised statements were presented in Round 2, and accepted statements were consolidated into key messages. Results: In total, 108 respondents (67 % female; mean [SD] age 41.4 [10.9] years) from 16 countries (five continents) completed Round 1. Fourteen statements were accepted (88–100 % agreement) and 10 were rejected (8–39 % agreement). The remaining nine statements (52–69 % agreement) were revised, and two new statements were developed for Round 2, which was completed by 89 (82 %) respondents. Five Round 2 statements were accepted (82–93 % agreement). Seven key messages were developed from 19 accepted statements, highlighting that remote care should be accessible to older adults with requisite capabilities, is feasible for older adults and health professionals with adequate support and training, and requires guidelines, policies, and further research to support wider adoption. Conclusions: The findings of this Delphi process can inform the implementation of remote care approaches for assessing and managing physical function in older adults.

Board Of Pharmacy, Makenna Haskill, Katie Gonzalez, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

A Correlational Study Exploring The Influence Of Organizational Climate On Job Satisfaction Of Non-Faculty Staff At Texas Community Colleges, Tamesha M. Hilliard-Daniels

Electronic Theses and Dissertations

As U.S. higher education institutions face increasing challenges related to employee morale and retention, understanding the drivers of workplace satisfaction is critical for institutional stability. This research investigates the relationships between organizational climate factors and job satisfaction among staff within Texas community colleges, applying Maslow’s hierarchy of needs and Herzberg’s motivator-hygiene as the theoretical framework. Specifically, this study explores the influence of institutional communication, employee well-being, and organizational mission and pride on staff job satisfaction. Utilizing a quantitative correlational design, the study analyzed secondary data from ModernThink’s Higher Education Insight Survey©. The sample consisted of 2,265 higher education professionals collected …

When Work Is Not Enough: Food Insecurity Among Employed Latinos Receiving Snap In Massachusetts And The Burden Carried By Latina Women, Phillip Granberry, Rafael M. Pérez Medina, Florita Coto Tristán

Gastón Institute Publications

Across Massachusetts, many SNAP recipients are workers, caregivers, parents, elders, people with disabilities, and families navigating low wages, unstable work schedules, high housing costs, and limited access to wealth building opportunities. Many of these workers held jobs that were labeled “essential” during the COVID-19 pandemic: food service, caregiving, cleaning, healthcare support, retail, transportation, construction, and other service sector jobs. Yet the public recognition of their essential labor has not been translated into adequate wages, benefits, or economic security.

Understanding What Works In Disseminating Clinical Practice Guidelines: A Qualitative Evidence Synthesis, Sumanth Kumbargere Nagraj, Tandekile Lubelwana Hafver, Valerie Reinthaler, Stijn Van De Velde, Carlos Zaror, Yan Jiao Shen, Susan Banda, Talitha Mpando, Gertrude Kunje, Suzgika Lakudzala, Ameer Hohlfeld, Emmanuel Effa, Denny Mabetha, Thomas Agoritsas, Per Olav Vandvik, Nicolas Delvaux

Peninsula Dental School

Objective To identify the barriers and facilitators that influence the dissemination of clinical practice guidelines (CPGs) and to explore the perceived usefulness, practical utility, expectations, and unmet needs of end users in relation to current dissemination strategies. Methods This qualitative evidence synthesis (QES) is a part of mixed-methods evidence synthesis. We searched literature from MEDLINE, Embase, CINAHL, Web of Science, Scopus, Epistemonikos, and Agency for Healthcare Research and Quality and Medical Guidelines Clearing house on January 30, 2025. Screening, data extraction and quality appraisal of the included studies were done by at least two authors independently and in duplicate. We …

Naturalistic Classroom And Home Practices To Support Executive Function And Self-Regulation Of Typically Developing Preschool Children Between The Ages Of 3-5 Years Old: A Mixed Method Study, Michelle Ann Burek

Rehabilitation Sciences Theses & Dissertations

Executive function (EF) and self-regulation (SR) are foundational developmental processes supporting young children’s participation in play, learning, social relationships, and everyday occupations. Although important to school readiness, social competence, health, and well-being, these skills are often examined in structured settings rather than the natural environments in which children develop. Guided by ecological, developmental, and occupational therapy perspectives, this dissertation examined EF and SR within children’s everyday participation and explored caregiver and teacher roles in supporting these processes.

This dissertation consists of three interconnected studies. The first was a systematic review of peer-based interventions to improve social participation among children and …

Effects Of Beverage Color During Mouth Rinsing On Measures Of Muscular Endurance, Muscular Strength, And Exercise Perceptions During Isometric Handgrip Testing, Sydney Andrews

Exercise Science Theses & Dissertations

Previous research has shown that color can influence psychological responses, physiological responses, and exercise performance. These effects have been previously attributed to learned associations or expectations which may influence exercise-related outcomes. This study aimed to investigate whether beverage color influences muscular performance during intermittent isometric handgrip exercise. This randomized, single-blind, deceptive crossover study consisted of 34 physically active adults (21.9±3.1 years) who completed a handgrip endurance test under three conditions: red beverage rinse, clear beverage rinse, and no-rinse. Participants were informed that the study would examine the effects of mouth rinsing two commercially available carbohydrate containing sport drinks on muscular …

Post-Vaccination Confidence In Covid-19 Vaccines And Associated Determinants In Post-War Context Of Tigray, Northern Ethiopia: A Mixed-Methods Study, Genanew Kassie Getahun, Yohannes Addisu Wondimagegne, Alemayehu Deressa, Barkot Tamiru, Trhas Tadesse Berhe, Moges Mekonnen, Tsegay Hadgu, Znabu Hadush Kahsay, Mussie Alemayehu, Gebrehaweria Gebrekurstos, Joy Kenyi, Eshetu Girma, Finina Abebe Ware, Nardos Gelana, Menen Tsegaw, Eyob Ketema Bogale, Asaye Alamneh Gebeyehu

Research outputs 2022 to 2026

Introduction It is widely recognized that access to and utilization of health services are negatively impacted by war. These effects worsen particularly when combined with pandemics such as COVID-19. Therefore, this study aimed to assess adults' COVID-19 post-vaccination confidence in the conflict-affected region of Tigray, Northern Ethiopia. Methods The study employed a concurrent parallel mixed-methods design, combining a quantitative survey of 1599 adults and six key informant interviews and six focus group discussions. Survey participants were selected using a multistage cluster sampling technique, while qualitative participants were purposively sampled. Quantitative data were collected using a pre-tested, structured questionnaire administered via …

Cardiovascular Health And Life Expectancy In Chronic Kidney Disease, Peipei Liu, Di Liu, Yulong Lan, Qi Zhang, Qiao Lu, Kang An, Jingyu Wang, Shuohua Chen, Shouling Wu, Youxin Wang

Research outputs 2022 to 2026

Chronic kidney disease (CKD) affects approximately 674 million people worldwide and accounted for 35.6 million years of life lost in 2021.1 Premature mortality in CKD is driven largely by cardiovascular disease (CVD),2 and management of modifiable cardiometabolic risk factors remains essential alongside pharmacological renoprotection. Life's Essential 8 (LE8),3 a validated composite measure of cardiovascular health (CVH), has been associated with lower mortality in CKD,4 yet prior studies have relied on relative risk estimates, leaving the absolute survival benefit and the extent to which high CVH can close the life-expectancy gap between patients with and without CKD unclear. We therefore examined …

Dietary Patterns And Cognitive Decline In Older Adults: Findings From The Western Australia Memory Study, Carolina Blagojevic Castro, Samantha L. Gardener, Farzana Jahan, Juliana Chen, Belinda M. Brown, Ruey L. Loo, Kevin Taddei, Stephanie R. Rainey-Smith, Michael Weinborn, Ana Caroline R.Dos Reis, Manohar L. Garg, Ralph N. Martins, Hamid R. Sohrabi

Research outputs 2022 to 2026

Background: Preventive strategies, including adherence to specific dietary patterns, have received increasing attention as approaches to reduce cognitive decline and dementia risk. However, findings remain inconsistent, partly due to differences in dietary assessment methods, cognitive outcomes, and THE consideration of genetic susceptibility factors such as apolipoprotein E (APOE) genotype.

Methods: This study examined associations between dietary patterns and longitudinal cognitive change in 185 older adults without dementia from the Western Australia Memory Study. Participants completed a food frequency questionnaire at baseline and underwent comprehensive neuropsychological assessments at baseline and up to five follow-up visits at 18-month intervals. Composite scores were …

Dietary Vitamin K Intakes And Atherosclerotic Cardiovascular Disease Incidence: Findings From The Uk Biobank, Montana Dupuy, Chengfeng Li, Pratik Pokharel, Liezhou Zhong, Benjamin H. Parmenter, Simone Radavelli-Bagatini, Jack Dalla Via, Allan Linneberg, Jette Jakobsen, Tilman Kühn, Aedín Cassidy, Jonathan M. Hodgson, Joshua R. Lewis, Marc Sim, Nicola P. Bondonno

Research outputs 2022 to 2026

Background and aims: Vitamin K is essential for processes that inhibit vascular and valvular calcification, attributes of atherosclerotic cardiovascular diseases (ASCVDs) and aortic stenosis (AS). Relationships between dietary vitamin K1 and K2 intakes, ASCVD and AS were explored.

Methods: In 112,111 participants from the UK Biobank without ASCVD or AS (median age 59.7 years, 57.3% female), dietary vitamin K1 (μg/day) and K2 (μgPKeq/day) intakes were calculated from Oxford WebQ 24-h dietary questionnaires, using vitamin K food composition databases. Associations with incident ASCVD, ASCVD subtypes and AS, obtained from self-reports, primary care data, hospital records and death registries, were examined using …

Unilateral Numbers Need Context: Reference Values For Single-Leg Cmj Performance Relative To Bilateral Cmj Capacity, Karol Kruczek, Tim Gabbett, Jason Lake, Michał Nowak

Research outputs 2022 to 2026

The single-leg countermovement jump (SL CMJ) is widely used to assess limb-specific neuromuscular function, with interpretation commonly centred on inter-limb asymmetry. However, contextualising unilateral performance relative to bilateral capacity remains less clearly defined. This retrospective cross-sectional study aimed to develop exploratory descriptive benchmarks for SL CMJ kinetic, kinematic, and temporal variables expressed as a percentage of bilateral CMJ performance in a heterogeneous athletic cohort. A total of 348 athletes completed bilateral and unilateral CMJs using dual force plate sampling at 1000 Hz. The best trials were selected using the modified reactive strength index (mRSI), and averaged unilateral variables were expressed …

Engagement Of Understudied Populations As Community Change: The South Texas Adrc Model, Gladys E. Maestre, Neela K. Patel, Rosa V. Pirela, Robin C. Hilsabeck, Kendra Stine, Neyra García, Roberto Reyes, Omar Oropeza, Cristian Maestre, Jesus D. Melgarejo, Sarah Williams-Blangero, Ney Alliey Rodriguez

School of Medicine Publications

Many populations experiencing the highest burdens of Alzheimer's disease and related dementias remain understudied, in part because traditional recruitment and retention models are insufficient to support sustained engagement. The Outreach, Recruitment, and Engagement Core (OREC) of the South Texas Alzheimer's Disease Research Center reconceptualized participant recruitment as a long-term system change in a Hispanic-majority, urban–rural region. OREC institutionalizes shared power through community advisory governance, aligns research protocols with local lived realities (through patient navigators, community health workers/promotores, and decentralized access points), and employs a data-driven feedback loop for continuous improvement. In 1 year, 46 outreach events touched 10,134 individuals (71% …

Validation Of A Portable Electrochemical Sensor For Real-Time Soil Nitrate Monitoring In Cotton Rhizosphere, Mohammad Solaiman, Elvis D. Sangmen, Ali Reza Galib, Tushar C. Sarker, Anil C. Somenahally, Shawana Tabassum

Electrical Engineering Faculty Publications and Presentations

Soil nitrate (NO3) exhibits rapid spatial and temporal variability that conventional point-sampling methods cannot effectively capture, limiting timely nutrient management and plant stress detection. This study aimed to validate a low-cost, threedimensional- printed electrochemical NO3 sensor for continuous in-soil monitoring and to evaluate whether sensor-derived NO3 dynamics reflect plant physiological responses. For this purpose, cotton (Gossypium hirsutum L.) plants were grown in pots under greenhouse conditions. The sensor was evaluated in two sequential phases: an initial calibration phase to characterize sensor response across a broad NO3 concentration range, followed by a validation phase in the cotton plant rhizosphere. In the …

Sarcopenic Obesity And Dementia Risk: Primary Associations And Landmark Analyses Of Muscle Strength And Body Composition Trajectories, Zhongyang Guan, Blossom C.M. Stephan, Lorenzo M. Donini, Justyna Godos, Giuseppe Grosso, Leticia Radin Pereira, Carla M. Prado, Carlos J. Toro-Huamanchumo, Jonathan C.K. Wells, Marc Sim, Mario Siervo

Research outputs 2022 to 2026

Background and aims: Sarcopenic obesity (SO) has been proposed as a risk factor for cognitive impairment. Yet evidence is inconsistent and often limited by heterogeneous definitions and lack of longitudinal assessments. This study aimed to examine associations of SO with all-cause and subtype-specific dementia, and to assess dose–response patterns and how longitudinal changes in body composition and muscle strength relate to dementia risk. Methods: We included 489,972 adults (mean age 56.5 ± 8.1 years) followed for a median of 13.6 years. SO was defined using the Sarcopenic Obesity Global Leadership Initiative (SOGLI) criteria. Cox models estimated hazard ratios (HRs) for …

Right-Sized Glycolysis In Growing Children: A Muscle Mass-Based Scaling Perspective, Sébastien Ratel, Joffrey Bardin, Anthony J. Blazevich

Research outputs 2022 to 2026

No abstract provided.

Plant-Based Diets, Ultra-Processed Foods, And Risks Of Mortality And Major Chronic Diseases: A Prospective Cohort Study, Alysha S. Thompson, Amy Jennings, Nicola P. Bondonno, Aedín Cassidy, Tilman Kühn

Research outputs 2022 to 2026

Background: Higher-quality plant-based diets (PBDs) are associated with lower risks of mortality and chronic disease, but whether ultra-processed food (UPF) content affects these associations remains unclear. We examined whether UPF content influences the relationship between plant-based dietary patterns and risks of mortality and major chronic diseases, accounting for nutrient quality. Methods: This prospective cohort study included 124,836 UK Biobank participants aged 40–70 years (recruited 2006–2010). Dietary intake was assessed using the Oxford WebQ 24-h recall. Four modified Plant-Based Diet Indices (PDIs) were derived to distinguish healthy (hPDI) and unhealthy (uPDI) patterns with high- and low-UPF content, using the Nova classification …

Changement Climatique Et Adolescentes En Afrique De L’Ouest Et Du Centre : Vers Une Réponse Centrée Sur Les Filles, Mame Soukeye Mbaye, Sarah Engebretsen, Maty Dia, Karen Austrian

Adolescents and Young People

La série « L’avenir des filles en point de mire : données probantes d’Afrique de l’Ouest et du Centre » examine les défis auxquels font face les adolescentes de la région et met en lumière des approches éclairées par les données probantes pour améliorer leurs conditions de vie. Cette note de recherche synthétise les données probantes sur la manière dont les chocs climatiques bouleversent la vie des adolescentes en Afrique de l’Ouest et du Centre (AOC), en s’appuyant notamment sur les données issues des pays prioritaires du GIRL Center. Elle examine les vulnérabilités climatiques liées au genre, les lacunes des …