Entire DC Network | Open Access Articles | Digital Commons Network™

Cardiovascular–Kidney–Metabolic Syndrome Through The Lens Of Gut‑Derived Uremic Toxins, Chudan Xu, Matthew Snelson, Francine Z. Marques

Research outputs 2022 to 2026

Cardiovascular–Kidney–Metabolic (CKM) syndrome represents a complex, interconnected cluster of cardiovascular disease, chronic kidney disease, and metabolic disorders such as obesity and type 2 diabetes. These conditions share overlapping metabolic, inflammatory, and vascular pathways, with the gut microbiome increasingly recognised as a key contributor and common underlying risk factor. Uremic toxins, traditionally considered waste products of host and microbial metabolism, are now recognised as active mediators of tissue damage across the CKM spectrum, particularly in the context of impaired renal function. Their production and accumulation are amplified by disrupted intestinal barrier integrity, chronic inflammation, and reduced renal clearance, collectively driving systemic …

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Dose–Response Association Between Systemic And Dermatologic Glucocorticoid Use And Type 2 Diabetes Mellitus: A Nationwide Case–Control Study, David Vadsholt, Annika V. Kvist, Chano Sandiramoorthy, Joshua R. Lewis, Peter Vestergaard, Johan Røikjer, Nicklas H. Rasmussen

Research outputs 2022 to 2026

Aims: To investigate the association and dose–response between systemic and topical glucocorticoids and odds of Type 2 diabetes mellitus. Materials and Methods: We conducted a nationwide case–control study using Danish registry data from 2013 to 2021. People aged 40 years or older with incident type 2 diabetes mellitus (n = 149 113) were matched 1:3 with controls (n = 447 339) by age, sex and weighted Charlson Comorbidity Index. Glucocorticoid exposure was defined as ≥ 1 prescription within 1 year before the date of diagnosis and ≥ 2 within 3 years and classified as systemic or topical. Conditional logistic regression …

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Effect Of Melatonin On Alleviating Chilling Injury In Cold-Stored ‘Kensington Pride’ Mangoes: A Comparative Evaluation Of Long Vs Short Dip Time, Mekhala Dinushi Kananke Vithana, Hafiz Muhammad Shoaib Shah, Mahmood Ul Hasan, Zora Singh

Research outputs 2022 to 2026

Mangoes (Mangifera indica L.) are notably susceptible to chilling injury (CI) when stored below 13 °C. This temperature threshold is too high for extended storage. Therefore, the influence of postharvest immersion in melatonin (MT) (50, 75, 100 µmol L^{− 1}) for 120 min on CI in ‘Kensington Pride’ mangoes kept at 5 ± 1 °C for 21 or 28 d was investigated. The most effective MT concentration was 75 µmol L^{− 1} causing 36.3% reduction in CI incidence compared to control. To facilitate adoptability in commercial practice, the influence of 120 min vs. 5- and 3-min immersions …

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Joint Cancer Nurses Society Of Australia–Clinical Oncology Society Of Australia Position Statement On The Contribution Of Nurses To Cancer Survivorship Care In Australia, Raymond J. Chan, Gemma Mcerlean, Fiona Crawford-Williams, Carla Thamm, Carmel O'Kane, Nicolas H. Hart, Gillian Blanchard, Anne Mellon, Justin Hargreaves, Mei Krishnasamy, Michael Jefford

Research outputs 2022 to 2026

Aim: To describe the development, consultation, and endorsement process for a joint position statement from the Cancer Nurses Society of Australia (CNSA) and the Clinical Oncology Society of Australia (COSA) regarding the contribution of nurses to cancer survivorship care in Australia. Methods: A development team of nursing and oncology experts (n = 11) was convened in September 2025. The draft position statement was informed by key literature, including the COSA Model of Survivorship Care, Australian Cancer Plan, a modified Delphi study defining nurse capabilities in survivorship care, and an overview of systematic reviews on nurse-led care models. A consultation survey …

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Maternal Prebiotic Supplementation Modifies Associations Between Intrapartum Antibiotics And Infant Allergy, Summer V.M. Walker, Thomas R. Sullivan, Rachelle A, Pretorius, Nina D'Vaz, Johnny Lo, Johan Garssen, Jeffrey A. Keelan, Desiree Silva, Susan L. Prescott, Claus T. Christophersen, Debra J. Palmer

Research outputs 2022 to 2026

Background: Prebiotics promote growth of beneficial gut bacteria, whereas antibiotics can disrupt the microbial balance, reduce diversity, and potentially cause gut dysbiosis. This investigation aimed to determine whether antibiotic use before, during, or after birth altered the risk of infant allergic disease outcomes within a maternal prebiotic dietary supplementation trial. Methods: Maternal participants were allocated to consume daily prebiotics (galacto-oligosaccharides and fructo-oligosaccharides) or placebo (maltodextrin) powder from 18 to 20 weeks' gestation until 6 months postnatal. All infants had a family history of allergic disease. Maternal and infant antibiotic use was prospectively collected monthly throughout the trial intervention period, and …

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Negotiating Relationships With Food, The Body, And Physical Activity: Who Is The Healthiest Of Them All?, Valeria Varea, Victoria Evans, Dawn Penney, Eibhlish O'Hara

Research outputs 2022 to 2026

Healthy eating and regular exercise are things that many people aspire to, mainly for health reasons. However, these practices can be complex given broader societal discourses. This paper aims to critically interrogate the social conditions and discursive formations that underpin everyday exercisers’ relationships with food, the body, and physical activity by using biopower and biopedagogies as a theoretical approach, and healthism as a set of discourses. Photo elicitation interviews with vignettes were conducted with nine participants who were regular exercisers. We constructed three different scenarios from the interview data and the theoretical approach: 1. Anna: A performance-driven, health compliant, private …

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Deep Reinforcement Learning–Driven Multi-Omics Integration For Constructing Gtage: A Novel Aging Clock From Igg N-Glycome And Blood Transcriptome, Yao Xia, Syed Mohammed Shamsul Islam, Xingang Li, Abdul Baten, Xuerui Tan, Wei Wang

Research outputs 2022 to 2026

Previous studies have demonstrated that the immunoglobulin G (IgG) N-glycome and transcriptome are potential biochemical signatures of chronological and biological ages, and several aging clocks have been developed. By integrating the IgG N-glycome and transcriptome, we propose a novel aging clock, gtAge. We developed a deep reinforcement learning-based multiomics integration method called AlphaSnake. The results showed that AlphaSnake achieved a predicted coefficient of determination (R²) value of 0.853, outperforming the concatenation-based integration method (R² = 0.820). The gtAge estimated by AlphaSnake explained up to 85.3% of the variance in chronological age, which was higher than that in …

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Neuromotor Function Following Lower-Limb Muscle Or Tendon Injury: Systematic Review And Meta-Analysis, Jack Andringa-Bate, Moath Almusallam, Molly Coventry, Myles C. Murphy, Ebonie Rio, Tania Pizzari

Research outputs 2022 to 2026

Purpose: Alterations in neuromotor function occur following lower-limb injuries and might be a factor in recurrent injury. We evaluated if adults with previous lower-limb muscle or tendon injury demonstrate differences in neuromotor function compared with uninjured or control limbs. Methods: A systematic search of health databases MEDLINE, EMBASE, CINAHL, and SPORTDiscus was conducted from inception until the end of April 2024. Studies evaluating neuromotor function of adults with a history of lower-limb muscle or tendon injury compared to an uninjured contralateral or control limb were included. Inverse variance, random effects meta-analyses were used to generate effect estimates for neuromotor outcomes. …

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Sport Participation And The Pursuit Of Active And Healthy Lifestyles: Everyday Athletes’ Relationships With Eating And Exercise, Valeria Varea, Eibhlish O'Hara, Dawn Penney, Victoria Evans

Research outputs 2022 to 2026

Purpose – Athletes are more likely to experience eating and exercise disorders than non-athletes. Little is known about the incidence of eating and exercise disorders amongst non-elite participants, many of whom participate outside of club governance and support structures. The aim of this paper is to explore eating and exercise attitudes and behaviours amongst participants in both formal and informal sport and, in so doing, generate insights to inform future educational initiatives that seek to promote healthy and active lifestyles. Design/methodology/approach – An online survey was completed by 110 participants, 9 of whom were interviewed for the second phase of …

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How I Cook With No Kitchen: An Investigation Of How #Microapartment Kitchens Are Depicted On Tiktok, Joelie Mandzufas, Karen Lombardi, Dorian Winter, Sarah Foster, Siobhan Hickling, Gina S.A. Trapp

Research outputs 2022 to 2026

Background: Physical constraints of small apartment kitchens and the influence of the surrounding community food environment may impact food practices of apartment residents. Social media portrayal of these features may influence public perception of apartment living. Aim: This project aimed to describe the public depiction of small apartment kitchen and cooking facilities. Methods: Content analysis of TikTok videos posted with small apartment-related hashtags was determined the portrayal of kitchen facilities, residents’ food practices, and hypothesised barriers to healthy cooking and eating practices. Current residents of small apartments compared these video depictions to their own experience. Results: We found TikTok videos …

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Influence Of Chronotype On Cycling Performance In Simulated 20-Km Time Trials—A Pilot Study, Sabrina Forster, Sascha Schwindling, Chris Abbiss, Fabienne Döringer, Andreas Klütsch, Anne Hecksteden, Tim Meyer

Research outputs 2022 to 2026

The chronotype (CT) refers to an individual's diurnal preference towards morningness (M) or eveningness (E). The aim of this study was to determine the influence of chronotype on 20-km cycling performance throughout the day. Seventy-six competitive male cyclists and triathletes completed the Morningness-Eveningness Questionnaire to determine chronotype. Only participants categorised as ‘definite’ M- (n = 10) and E-types (n = 7) were included in the study. In a randomised order and separated by 2–7 days, participants performed four self-paced 20-km cycling time trials at four different times of the day (06:00 h, 12:00 h, 18:00 h, 22:00 h). Mental readiness …

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Full-Text Articles in Entire DC Network

Cardiovascular–Kidney–Metabolic Syndrome Through The Lens Of Gut‑Derived Uremic Toxins, Chudan Xu, Matthew Snelson, Francine Z. Marques

Research outputs 2022 to 2026

Dose–Response Association Between Systemic And Dermatologic Glucocorticoid Use And Type 2 Diabetes Mellitus: A Nationwide Case–Control Study, David Vadsholt, Annika V. Kvist, Chano Sandiramoorthy, Joshua R. Lewis, Peter Vestergaard, Johan Røikjer, Nicklas H. Rasmussen

Research outputs 2022 to 2026

Effect Of Melatonin On Alleviating Chilling Injury In Cold-Stored ‘Kensington Pride’ Mangoes: A Comparative Evaluation Of Long Vs Short Dip Time, Mekhala Dinushi Kananke Vithana, Hafiz Muhammad Shoaib Shah, Mahmood Ul Hasan, Zora Singh

Research outputs 2022 to 2026

Research outputs 2022 to 2026

Research outputs 2022 to 2026

Negotiating Relationships With Food, The Body, And Physical Activity: Who Is The Healthiest Of Them All?, Valeria Varea, Victoria Evans, Dawn Penney, Eibhlish O'Hara

Research outputs 2022 to 2026

Deep Reinforcement Learning–Driven Multi-Omics Integration For Constructing Gtage: A Novel Aging Clock From Igg N-Glycome And Blood Transcriptome, Yao Xia, Syed Mohammed Shamsul Islam, Xingang Li, Abdul Baten, Xuerui Tan, Wei Wang

Research outputs 2022 to 2026

Neuromotor Function Following Lower-Limb Muscle Or Tendon Injury: Systematic Review And Meta-Analysis, Jack Andringa-Bate, Moath Almusallam, Molly Coventry, Myles C. Murphy, Ebonie Rio, Tania Pizzari

Research outputs 2022 to 2026

Sport Participation And The Pursuit Of Active And Healthy Lifestyles: Everyday Athletes’ Relationships With Eating And Exercise, Valeria Varea, Eibhlish O'Hara, Dawn Penney, Victoria Evans

Research outputs 2022 to 2026

How I Cook With No Kitchen: An Investigation Of How #Microapartment Kitchens Are Depicted On Tiktok, Joelie Mandzufas, Karen Lombardi, Dorian Winter, Sarah Foster, Siobhan Hickling, Gina S.A. Trapp

Research outputs 2022 to 2026

Influence Of Chronotype On Cycling Performance In Simulated 20-Km Time Trials—A Pilot Study, Sabrina Forster, Sascha Schwindling, Chris Abbiss, Fabienne Döringer, Andreas Klütsch, Anne Hecksteden, Tim Meyer

Research outputs 2022 to 2026