Digital Commons Network^™

Fall Risk In Community-Dwelling Adults: A Comparison Of English And Spanish-Speaking Individuals, Jesus D. Gomez

Dissertations, 2020-current

Falls are a leading cause of injury-related mortality among middle-aged and older adults. Although vestibular dysfunction, hearing loss, behavioral factors, and social determinants of health have been associated with increased fall risk, few studies have examined these relationships. Furthermore, limited research in audiology and vestibular science has investigated fall-risk vulnerability among Spanish-speaking individuals.

This study aimed to: (1) estimate the prevalence of fall risk among community-dwelling adults and compare prevalence between English-speaking and Spanish-speaking participants; (2) assess the prevalence of previously undiagnosed benign paroxysmal positional vertigo (BPPV) and compare prevalence between language groups; and (3) develop predictive models of fall …

Cultural Tailoring Of Digital Nutrition Interventions: A Scoping Review Of Adaptation Strategies, Evaluation Methods, And Evidence Gaps, Wendy Liang

Master's Projects and Capstones

Background: Nutrition-related chronic diseases disproportionately affect culturally diverse populations, highlighting the need for effective and equitable interventions. Digital nutrition interventions have expanded rapidly due to their accessibility; however, the extent to which they incorporate and evaluate cultural tailoring remains unclear.

Research aim: This scoping review maps the existing evidence on culturally tailored digital nutrition interventions, describes cultural adaptation strategies used, examines methods used to evaluate cultural appropriateness, and identifies gaps for future research and public health practice.

Methods: A scoping review was conducted following the PRISMA-ScR guidelines.

Findings: Culturally tailored digital nutrition interventions generally improved participant engagement, acceptability, and dietary …

Establishing Partnerships Between Families, Schools, And Communities To Support Family Involvement In Literacy Education, Matraca Bourdo

Masters Projects

As the percentage of fourth grade students reading at a proficient level continues to decline, schools are seeking effective ways to improve literacy education and student achievement. Research emphasizes the importance of early literacy development in supporting academic success and lifelong learning. However, not all families have the same background knowledge of literacy skills and how to develop them with their children. Partnerships between schools, families, and communities can provide the support and resources needed while working toward the goal of improving student achievement.

The purpose of this project is to implement a team that partners with families to educate …

When Policy Meets Public Distrust: A Social Network Analysis On Indonesia's Mbg Program, Rizky Fauziah, Rehia Karenina Isabella Barus, Ressi Dwiana

JURNAL KOMUNIKASI INDONESIA

The Indonesian government program Free Nutritious Meal, locally abbreviated as MBG, launched in early 2025, has generated significant public controversy. Data from the Institute for Development of Economics and Finance (INDEF) indicate that, as of August 2025, approximately 4,000 students across Indonesia had reportedly suffered food poisoning associated with the program. This situation has fueled widespread public concern and contributed to declining trust in government. This study aims to analyze communication networks surrounding the MBG on the social media platform X. This study draws on Trust and Distrust Theory and employs a Social Network Analysis (SNA) approach to examine how …

Improving Nursing Adherence To Chg Bathing And Pivc Maintenance Practices To Reduce Hospital-Onset Bacteremia In An Adult Medical-Surgical Unit, Mohabat Barikzai, Dinazar Altamirano, Edward Rivas, Sarah Trilles

Master's Projects and Capstones

Preventing hospital-onset bacteremia (HOB) is a healthcare priority given its association with increased morbidity, mortality, prolonged hospitalization, and healthcare costs. Literature identifies inconsistent adherence to evidence-based practices for chlorhexidine gluconate (CHG) bathing and peripheral intravenous catheter (PIVC) maintenance as a modifiable risk factor for HOB. This quality improvement (QI) project evaluated whether implementing standardized nurse education, routine compliance audits, and performance feedback would improve adherence to evidence-based CHG bathing and PIVC maintenance practices. The project aimed to achieve at least 90% nursing compliance with HOB prevention practices over an intended 8-week implementation period. A pre-post quality improvement design was implemented …

Food For Thought: Building Confidence In Healthy Food Choices Among Seniors In A Residential Facility Through Nutrition Education, Amy Rodríguez

Master's Projects and Capstones

This quality improvement project evaluated the effectiveness of a 10-week nutrition education program designed to improve nutrition knowledge and confidence among independently living older adults residing in a low-income senior housing community. Aim By August 10, 2026, this project aimed to increase average nutrition knowledge and confidence scores related to selecting nutritious foods and preparing healthy meals by 20% among senior housing facility residents. Methods A microsystem assessment, literature review, SWOT analysis, fishbone diagram, and GANTT chart were completed to guide project development and implementation. Weekly nutrition education workshops were conducted over a 10-week period and included presentations, group discussions, …

Breaking The Silence: Standardizing Routine Intimate Partner Violence Screening At A Community Clinic Serving The Latinx Community, Victoria M. Hall

Master's Projects and Capstones

Intimate partner violence (IPV) affects the Latinx population disproportionately due to socioeconomic status, cultural stigma, and language barriers. However, routine screening remains inconsistent and unstandardized at a local community clinic in San Francisco’s Mission District, despite evidence-based practices recommending it. The gap in IPV screenings across the Adult, Teens, and Women’s clinics resulted in only 1.6% of patients being screened in July 2025 and 4.1% in June 2026. This quality improvement project aimed to address low screening rates by standardizing IPV screening through a printed bilingual screener, a 60-minute staff in-service on IPV and the new screening protocol, and by …

Nourishing Confidence: Empowering Seniors To Make Healthy Food Choices, Ina Patricia Bangawan

Master's Projects and Capstones

Objective This quality improvement (QI) project evaluated the effectiveness of a 10-week nutrition education program designed to improve nutrition knowledge and confidence in making healthy nutritional choices among independent older adults living in a low-income senior housing community. Aim By August 10, 2026 the goal of this project was to increase average nutrition knowledge and confidence scores related to selecting nutritious foods and preparing healthier meals by 20% among senior housing facility residents. Methods A microsystem assessment and gap analysis, literature review, SWOT analysis, fishbone diagram, and GANTT chart were completed to guide the project development and implementation. Weekly nutrition …

Steady Steps: Building Confidence In Parkinson’S Disease Care, Jerlyn T. Nicdao

Master's Projects and Capstones

Parkinson’s disease is a movement disorder that greatly impacts one’s quality of life due to its worsening progression and impact on cognitive and physical functions. Objective: The purpose of this quality improvement project is to strengthen staff confidence and competence in caring for residents with Parkinson’s disease (PD) living in a skilled nursing facility. Aim: Clinical nurse leader (CNL) students aim to increase staff confidence and competence in PD care from 60% to 75% over a six-week period, from June 18, 2026, to July 30, 2026. Method: A total of thirteen interdisciplinary staff members (e.g. registered nurses, licensed vocational nurses, …

Standardizing Gestational Diabetes Group Education In An Outpatient Maternal-Fetal Medicine Clinic: A Quality Improvement Project, Nina Prieto

Master's Projects and Capstones

Gestational diabetes mellitus (GDM) requires timely and consistent education to support effective self-management and reduce maternal and fetal complications. Baseline assessment of an outpatient maternal-fetal medicine clinic identified variation in educational materials, teaching approaches, referral processes, scheduling, and workflows across English- and Spanish-language GDM group visits. This quality improvement project aimed to standardize the group visit process and increase staff compliance with standardized materials and workflows from 0% to 50% over a 12-week period. Data were collected through direct observation of group and individual education sessions, stakeholder feedback, review of existing materials, referral and attendance patterns, and workflow analysis. These …

Enhancing Tea Productivity Through Integrated Fertilization And Pruning Management: A Review, Intan Ratna Dewi Anjarsari, Murgayanti, Muhamad Kadapi, Syariful Mubarok, Uum Umiyati, Salsabilah, Alifatul Azmi, Afifah Putri Ramadhan, Trifani Hana Husniah, Rosita, Azkal Azkiya

Jurnal Kultivasi

Tea productivity is strongly influenced by agronomic management practices, particularly fertilization and pruning, which play critical roles in regulating plant growth, physiological performance, and shoot regeneration. This review aims to synthesize current scientific evidence on how integrated fertilization and pruning management can sustainably enhance tea productivity. A narrative review approach was employed by collecting and analyzing peer-reviewed articles published between 2015 and 2025 from reputable databases, including Google Scholar and major international journals. The review highlights that balanced fertilization strategies, combining inorganic, organic, and biofertilizers, significantly improve nutrient availability, photosynthetic efficiency, and shoot yield. Pruning, when properly timed and executed, …

Differential Effects Of Thiamine, Bap, And Thidiazuron Combinations On Shoot Multiplication And Phenolic-Flavonoid Accumulation In Pineapple In Vitro Cultures, Dinda Septia Rachman, Erni Suminar, Anne Nuraini, Fiky Yulianto Wicaksono, Suseno Amien, Syariful Mubarok, Hermanto

Jurnal Kultivasi

The demand for high-quality pineapple (Ananas comosus (L.) Merr.) planting materials continues to increase, while conventional propagation methods are limited in multiplication rate, uniformity, and production efficiency. In vitro culture offers an alternative approach for rapid and large-scale seedling production. However, information on the effects of thiamine and cytokinin combinations on both shoot multiplication and phenolic-flavonoid accumulation in pineapple in vitro remains limited. This study evaluated ten defined combinations of thiamine and cytokinin for shoot multiplication and total phenolic-flavonoid contents of pineapple explants. The experiment employed a completely randomized design with 10 treatment combinations of thiamine (0.1 and 0.4 mg/L), …

Performance Of Dual-Form Terminalia Catappa Organic Fertilizers On Sweet Corn Yield And Economic Viability In Tropical Highlands, Stefina Liana Sari, Eso Solihin, Rahmat Budiarto

Jurnal Kultivasi

Recycling underutilized plant biomass into organic fertilizers underpins low-input cropping strategies, but liquid and solid formulations derived from a common feedstock have seldom been evaluated side by side under field conditions. This study aimed to (i) characterize the physicochemical properties and safety profile of a liquid organic fertilizer (LOF) and a crumb-type organic fertilizer (COF) co-produced from Terminalia catappa leaf compost, (ii) compare their effects on sweet corn growth and yield, (iii) determine relative agronomic effectiveness (RAE), and (iv) evaluate economic feasibility of the most promising organic–inorganic combinations. We produced LOF and COF through aerobic composting of Terminalia catappa leaves …

Metabolic Dynamics Of Secondary Metabolites In Arabica Coffee (Coffea Arabica): From Biosynthesis To Post-Harvest Transformations, Kamilrashid Hadi Dwitama, Yudithia Maxiselly, Cucu Suherman, Santi Rosniawaty

Jurnal Kultivasi

Coffee (Coffea arabica) is a globally significant beverage whose sensory profile and physiological effects derive from a complex matrix of secondary metabolites. This review presents a comprehensive "lifecycle" perspective of three pivotal classes: the alkaloid caffeine, phenolic chlorogenic acids (CGA), and the diterpenoids cafestol and kahweol. Here, 'lifecycle' defines a metabolite's continuous biochemical trajectory, tracking its genetic origin and ecological function in the plant through structural modifications during fermentation, drying, storage, and roasting. These classes are highlighted because they serve as the primary drivers of bitterness, acidity, and health bioactivities with fundamentally distinct transformational pathways. Following a systematic methodology, this …

The Effectiveness Of Bacillus-Coated Npk Fertilizer On Broccoli Growth, Nutrient Status, Rhizosphere Bacillus Population, Yield, And Flower Quality, Betty Natalie Fitriatin, Rara Rahmatika Risanti, Reginawanti Hindersah, Fasa Aditya Hanindipto, Gita Bina Nugraha

Jurnal Kultivasi

Efforts to increase the availability of macronutrients in soil have relied on inorganic fertilization, particularly NPK fertilizers. However, global challenges in the fertilizer raw material supply chain, including price fluctuations and availability, are driving the need for more efficient and sustainable fertilizer alternatives. The field experiment was conducted in Baruajak, Lembang District, West Java, Indonesia, to evaluate the effectiveness of Bacillus-coated NPK fertilizer on broccoli (Brassica oleracea var. italica) growth, nutrient status, rhizosphere Bacillus population, yield, and flower quality. The experiment used a randomized complete block design with 15 fertilizer treatments and three replications. Treatments consisted of two coated NPK …

The Effect Of Silica-Enriched Rice Husk Biochar And Npk Fertilizer On Soil Total Nitrogen, Nitrogen Uptake, And Yield Of Lowland Rice, Emma Trinurani Sofyan, Oviyanti Mulyani, Ania Citraresmini, Meddy Rachmadi, Kharmelia Sandra Livia

Jurnal Kultivasi

Rice production in Indonesia increasingly relies on agricultural intensification, which can accelerate soil degradation and reduce fertilizer-use efficiency. Therefore, sustainable soil management is needed to maintain soil fertility. Silica-enriched rice husk biochar (biochar-silica) is a promising soil amendment because it improves soil properties and nutrient retention. This study evaluated the effects of biochar-silica and NPK fertilization on soil total nitrogen, nitrogen uptake, and yield of lowland rice (Oryza sativa L.). The experiment was conducted from September 2025 to January 2026 using a two-factor randomized block design with nine treatment combinations and three replications. The treatment consisted of three levels of …

The Effects Of Melatonin And Potassium Fertilizer On Fruit Yield And Quality Of ‘Haruhi’ Strawberry Under Two Light Conditions, Ghaida Marsha Nurizqia, Farida, Reginawanti Hindersah, Kenji Endo, Rahmat Budiarto, Syariful Mubarok

Jurnal Kultivasi

Strawberry (Fragaria × ananassa) ‘Haruhi’ is a subtropical plant that is being cultivated in Indonesia. High temperatures in tropical climates could decrease strawberry yield and fruit quality. The purpose of this study was to evaluate the effect of light, melatonin, potassium fertilizers, and their interactions on the yield and fruit quality of ‘Haruhi’ strawberry. This research was conducted from April to June 2024 at the Bale Tatanen, Faculty of Agriculture, Universitas Padjadjaran. A split-plot design was used, with lighting treatment as the main plot and melatonin and potassium fertilizer treatments as the subplot. Lighting treatments consisted of supplemental LED lighting …

Effects Of Ab Mix Hydroponic Solution And Ameliorant Mixtures On Cayenne Pepper Growth And Yield In An Inceptisols, Tien Turmuktini, Betty Natalie Fitriatin, Tualar Simarmata, Firda Widayanti, Nuryanti, Lia Amalia, Elly Roosma Ria, Linlin Parlinah

Jurnal Kultivasi

Cayenne pepper (Capsicum frustescens L.) cultivation faces several problems, including acidic pH and inadequate nutrient management. These problems can be addressed by using a mixture of various ameliorants and AB mix nutrient solutions. This study aimed to determine the effect of ameliorant mixture dosage and AB mix solution concentration on soil chemical properties, growth, and yield of cayenne pepper. The experiment used a randomized block design, consisting of two factors: nutrient solution concentration and ameliorant dosage. The factor of nutrient solution concentration consisted of four levels, i.e., 700, 1000, 1300, and 1600 ppm, while the factor of ameliorant dosage also …

Land-Use Transitions And Carbon Emissions Of Aquaculture Expansion In The Brazilian Amazon, Felipe S. Pacheco, Sebastian A. Heilpern, Rafael M. Almeida, Suresh A. Sethi, Marcela Miranda, Nicholas Ray, Laura Greenstreet, Joshua Fan, Brendan H. Rappazzo, Marcelo Gomes Da Silva

School of Earth, Environmental, & Marine Sciences Faculty Publications

Accounting for land-use change underlying food sector expansion is critical for conserving ecosystem integrity. This challenge is particularly acute in the Amazon, where the conversion of forests for food production is pronounced and has broad implications for global biodiversity and the cycling of water and carbon. Here, we analyze land-use transitions associated with aquaculture development in the Brazilian Amazon. We found that a 450-fold increase in aquaculture pond area from 1985 to 2022 occurred primarily on pasturelands (87%) but also included wetland conversion (4%) and deforestation (5%). Notably, continued growth can be sustained within already altered landscapes: In Rondônia, the …

Community School Hubs: A Path To Literacy For English Learners And Families, Elizabeth Ortiz-Wright

The Reading Professor

This qualitative narrative study examined the perceptions of community school hub members and Hispanic English learner parents at an elementary school in a suburban district. Eighty-four percent of the students at the study site were economically disadvantaged. The inquiry drew on sociocultural theory and Bronfenbrenner's ecological systems theory to explore how these hubs support families. Data were gathered through semi-structured interviews and field observations and analyzed using Quirkos software. The findings demonstrate the overall value of community school hubs in addressing basic needs, increasing the potential for academic success. However, a significant lack of clarity exists; many parents were unaware …

Investigation Of The Functional Dimensions Of Teats Up To Mid-Lactation In Bulgarian Murrah Buffaloes Established By Ultrasonography, Ivan Fasulkov, Pencho Penchev, Yordanka Ilieva, Manol Karadaev

The Thai Journal of Veterinary Medicine

The aim of this study was to monitor the changes in teat measurements from early to mid-lactation in the Bulgarian Murrah buffaloes. The experiment was carried out with twenty (10 primiparous and 10 pluriparous) lactating buffaloes. Five series of ultrasound measurements were performed, each consisting of two sessions for each animal corresponding to the phases of lactation: first lactation month (day 1 to day 30 postpartum) and mid- lactation (day 122 to day 152). The studied parameters were teat canal length (TCL), teat diameter (TD), teat wall thickness (TWT), and teat cistern diameter (TCD). The data were processed using the …

An In-Depth Study Of Fruit Preservation: Effect Of Calcium Chloride And Methyl Jasmonate Applications On Quality And Biochemical Properties Of Cherry Fruits During Cold Storage, Muhammet Ali̇ Gündeşli̇

Turkish Journal of Agriculture and Forestry

Sweet cherry (Prunus avium L.) is a highly perishable fruit that undergoes rapid quality deterioration during postharvest storage. This study evaluated the effects of postharvest applications of Methyl Jasmonate (MeJA, 1 mM) and Calcium Chloride (CaCl₂, 2%), applied individually and in combination, on maintaining the quality and biochemical properties of cherries during 21 days of cold storage at 0 ± 1 °C. Key parameters including weight loss, decay rate, soluble solids content (SSC), pH, titratable acidity, respiration rate, phenolic profile, and organic acid composition were monitored. The combined MeJA + CaCl₂ treatment was consistently more effective than individual applications in …

Sewage Sludge Legislation In Central Europe: Contamination Concerns And Cross-Border Comparisons, Valerie Vranová, Aleš Kučera, Vlastimil Skoták, Erika Fialová, Rahul Datta

Turkish Journal of Agriculture and Forestry

Sewage sludge management represents a major challenge in Europe, carrying significant environmental and legal implications that require strong regulatory enforcement. Here, we explore the legislative measures, technological developments, and environmental impacts of sewage sludge management in Central Europe (Czechia, Slovakia, Germany, Austria, and Poland). Sludge management is regulated at the EU level through a series of directives (e.g., Council Directive 86/278/EEC, which forms the basis of national regulatory frameworks). However, national adaptations vary considerably: Croatia and Slovenia have invested in sludge phosphorus-recovery systems, while Poland and Slovakia have focused on the agricultural use of sludge as a fertilizer. Several countries, …

Male Osteoporosis: Pathophysiology, Risk Assessment, And Evidence-Based Management, Seli̇n Teki̇n, Alper Gürlek

Turkish Journal of Medical Sciences

Osteoporosis in men is a common yet underrecognized condition associated with substantial fracture-related morbidity and excess mortality. Although men generally attain higher peak bone mass than women, age-related changes in bone microarchitecture, progressive cortical bone loss, declining sex steroid bioavailability, and a high prevalence of secondary causes contribute to a significant lifetime fracture risk. Importantly, a large proportion of fragility fractures in men occur at bone mineral density (BMD) values above the osteoporotic threshold, highlighting the limitations of BMD-based diagnosis alone. This review provides a comprehensive overview of the epidemiology, pathophysiology, and clinical characteristics of osteoporosis in men, with particular …

A Comparative Analysis Of Clinical Quality And Readability Of Neuropathic Pain Patient Information Leaflets: Türkiye Versus The United States, Gonul Sari, Argun Pire

Turkish Journal of Medical Sciences

Background/aim: Neuropathic pain management requires high patient adherence and complex dose-titration regimens, making the readability of patient information leaflets (PILs) a critical patient safety factor. This study aimed to compare the clinical content quality and linguistic readability of PILs for neuropathic pain medications between Türkiye (TİTCK) and the United States (DailyMed).

Materials and methods: A total of 11 pairs of innovator medications were analyzed. Clinical content was assessed using the 15-item Keystone Clinical Content Checklist (KCCC). Readability was assessed using the Ateşman index for Turkish texts and the Flesch Reading Ease Score (FRES) for English texts. Information quality and reliability …

Comparing Age Of Obesity Onset, Concerns About Weight And Body Shape, And Quality Of Life In Individuals Seeking Bariatric Surgery ​, Vi̇ldan Çakir Kardeş, Özge Saraçli, Nuray Atasoy, Levent Ati̇k, Si̇bel Kahraman Gi̇rgeç

Turkish Journal of Medical Sciences

Background/aim: This study explored the relationship between concerns about weight and body shape and quality of life in bariatric surgery candidates with morbid obesity regarding the onset of the weight problem in childhood, adolescence, or adulthood.

Materials and methods: We included 453 patients who applied to our center for preoperative bariatric surgery assessment between January 2010 and April 2019. We reviewed the sociodemographic information, psychiatric diagnoses, and results of the Body Shape Questionnaire-34, Quality of Life Scale, Beck Depression Inventory, and Beck Anxiety Inventory of all patients.

Results: Concerns about weight and body shape were increased in women (p < 0.001), unemployed patients (p = 0.001), those with a comorbid psychiatric disorder (p < 0.001), and those with childhood- or adolescent-onset of weight problems (r = –0.170; p < 0.001). Concerns about weight and body shape had a relationship with the vitality (r = –0.434), mental health (r = –0.464), social functioning (r = –0.418), pain (r = –0.307), and general health (r = –0.352) subscale scores of quality of life. Physical functioning was higher (p = 0.037) in patients with childhood- or adolescent-onset obesity compared to patients with adult-onset obesity, while mental health was higher (p = 0.001) in the latter group. Individuals with childhood- or adolescent-onset obesity inquired about bariatric surgery options at an earlier age (p < 0.001).

Conclusion: …

Lactate Dehydrogenase-To-Albumin Ratio As A Novel Prognostic Biomarker For 28-Day Mortality In Thoracic Trauma: A Single-Center Retrospective Cohort Study ​, Özgür Ömer Yildiz, Şükrü Yorulmaz, Eray Çinar, Hüseyi̇n Mutlu, Rami̇z Yazici, Ayşenur Gür, Medi̇ne Akkan Öz, Bensu Bulut, Mustafa Sirri Kotanoğlu, Hakan Güner

Turkish Journal of Medical Sciences

Background/aim: Thoracic trauma accounts for approximately 25% of all trauma-related deaths and remains a significant public health challenge. Early identification of high-risk patients is essential for improving clinical outcomes. The present study evaluates the prognostic value of the lactate dehydrogenase-to-albumin ratio (LDAR) in predicting 28-day mortality in patients with thoracic trauma.

Materials and methods: This retrospective observational study was conducted at a Level 1 trauma center between September 2022 and February 2025, and included adult patients presenting with thoracic trauma who underwent thoracic computed tomography. Demographic characteristics, clinical parameters, laboratory values, and 28-day mortality were analyzed. Receiver operating characteristic (ROC) …

C-Reactive Protein–Albumin–Lymphocyte (Cally) Index As A Novel Inflammatory Marker For Sarcopenia: Evidence From A Cross-Sectional Study ​, Yasemi̇n Polat Özer, Merve Güner, Serdar Ceylan, Engi̇n Çeşmeci̇, Cafer Balci, Burcu Balam Doğu, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Mert Eşme

Turkish Journal of Medical Sciences

Background/aim: Sarcopenia is a geriatric syndrome characterized by progressive impairments in skeletal muscle mass and performance, with chronic low-grade systemic inflammation playing a pivotal role in its development. The C-reactive protein–albumin–lymphocyte (CALLY) index reflects inflammatory burden alongside immune and nutritional status; however, its association with sarcopenia in older populations has yet to be sufficiently elucidated. The present study investigates the relationship between CALLY index values and probable sarcopenia (PS) in a large cohort of geriatric outpatients.

Materials and methods: Included in this retrospective cross-sectional study were 2042 geriatric outpatients aged ≥65 years who were assessed between May 2022 and March …

Vitamin D Deficiency, Depression Severity, And Suicide Risk: Evidence From Patients With Major Depressive Disorder ​, Eli̇f Küçük, Feri̇de Uysal, Seda Şenkardeş Kandemi̇r, Özgür Özkalayci, Canay Pamukçu, Ni̇hal Taşteki̇n, Meri̇h Altintaş

Turkish Journal of Medical Sciences

Background/aim: Major depressive disorder (MDD) is a common psychiatric condition characterized by depressive symptoms and suicide-related clinical features. Vitamin D status has been investigated as a potential clinical correlate of depression and suicidal ideation, but the direction and specificity of these associations remain uncertain. This cross-sectional study aimed to examine the associations among serum 25-hydroxyvitamin D [25(OH)D] levels, depressive symptom severity, suicidal ideation, and suicide-related cognitive–affective dimensions in adults diagnosed with MDD.

Materials and methods: This cross-sectional study included 97 adults aged 18–65 years who were diagnosed with MDD according to DSM-5 criteria. Depressive symptom severity and suicide-related outcomes were …

L-Theanine Attenuates Alcl3-Induced Cognitive Dysfunction And Neurotoxicity In Rats: A Behavioral And Biochemical Study, Muhammet Oğuzhan Dönmez, Azi̇ze Şener, Şeyda Karaman Ersoy, Mahdi̇ Marzi̇, Göksel Şener

Turkish Journal of Medical Sciences

Background/aim: The effects of L-theanine (LTN), a natural compound found in tea leaves, on biochemical parameters and cognitive functions were investigated in an aluminum chloride (AlCl3)-induced Alzheimer’s disease-like experimental model.

Materials and methods: A total of 32 male Wistar rats were allocated into four groups: control, AlCl3-induced AD-like group, LTN-treated AD-like group, and donepezil-treated AD-like group. Donepezil was used as a reference drug. For the induction of AlCl3- induced neurotoxicity, AlCl3 was administered by gavage at a dose of 25 mg/kg/day during the 1st week and 150 mg/kg/day for the subsequent 3 weeks. LTN was administered orally at a dose …