Digital Commons Network^™

Anthropometric And Lifestyle Metrics Compared In Postmenopausal Women, Amanda Louise Daniel

Theses

Background: Hormone changes and aging that lead to menopause have a significant impact on quality of life. Understanding health thresholds for the components of body composition in this population are not well known. The relationship between menopausal symptoms and lifestyle factors is understudied. Methods: A mixed-methods approach included surveys and face-to-face body composition analysis using bioelectric impedance. Eating competence, sleep quality, and physical activity were assessed online with validated surveys prior to body composition measurement. Data were transformed to normality and analyzed with Pearson correlation coefficients and independent t-test correcting for multiple comparisons. Results Of the 69 interested people, 50 …

Evaluating The Impact Of Positional Isometric Contractions On Upper-Body Strength In Adolescent Athletes, Maurice Harden

Doctorate in Kinesiology

This study examined the effects of positional isometric contractions used as a pre-exercise warm-up on upper-body strength in adolescent male athletes. Twenty participants were randomly assigned to either a positional isometric group or a positional stretching group. Peak isometric force was measured using the VALD Force Decks System across three consecutive testing sessions. Data were analyzed using a three-week by two-group mixed design analysis of variance. The results showed no statistically significant differences between warm-up methods or across testing sessions. However, the positional isometric group demonstrated slightly higher initial force values that leveled out with repeated testing. These findings suggest …

Icsb Poster Session, Ikhlas Khan

Oxford ICSB

Poster abstracts from the ICSB 2026 poster session.

Metabolomic Characterizations Of Hericium Erinaceus (Bull.) Pers. And Laricifomes Officinalis (Vill.) Kotl. & Pouzar Fungal Cultures, Kyle Meyer

Oxford ICSB

We present metabolomic characterizations of Hericium erinaceus (Bull.) Pers. (lion’s mane, yamabushitake, etc.), and Laricifomes officinalis (Vill.) Kotl. & Pouzar (syn. Fomitopsis officinalis; agarikon, eburiko, etc.) fungal cultures by high resolution orbitrap mass spectrometry and HPLC-DAD. Primary focus has been applied to the cultivation of these species on brown rice, Oryza sativa L., as a solid substrate.   In the case of H. erinaceus, we have observed key differences in lipid metabolite profiles over a 28-day fermentation time series suggesting possible grain lipid feedstocks for fungal-derived lipid production, providing clear evidence of substrate biotransformation.   For L. officinalis cultures, we observe distinct …

Bioactive Metabolite Markers For Functional Mushrooms: Comprehensive Metabolomic Mapping Of Full-Spectrum Cultivated Mushrooms, Standard Production And Method Development., Julie Daoust, Ivana Blaženović

Oxford ICSB

Functional mushrooms are increasingly used in dietary supplements and functional foods, yet current scientific characterization of their chemistry remains limited by narrow extraction paradigms, limited standards availability and incomplete databases. In 2025, M2 Ingredients, in collaboration with Adikai Insights, completed a metabolomics atlas, a comprehensive untargeted metabolomics investigation of ten cultivated mushroom species grown under controlled indoor conditions in and effort to identify known bioactive molecules in whole mushroom samples to guide standard and quantitative method development targeting bioactive compounds present in the materials.   Using high-resolution mass spectrometry and advanced cheminformatics, a total of 5,139 unique functional mushroom metabolites were …

Authenticated Hericium Erinaceus Mushroom And Selected Mycelia Reference Materials For General Industry Use, Steven Dentali

Oxford ICSB

The establishment of authenticated reference materials is critical for method validation, standards development, and adulteration detection in the medicinal mushroom market. Hericium erinaceus (Lion’s Mane) is widely commercialized, yet historically has lacked species-specific analytical standards. This presentation describes the species identification protocol used by Nammex to develop and maintain authenticated H. erinaceus mushroom reference materials that support ongoing standards work, including advisory contributions to AOAC INTERNATIONAL initiatives. Production partner voucher specimens are authenticated using macroscopic, organoleptic, and morphological examination by qualified personnel, and retained as internal reference materials. Genetic verification using DNA sequencing confirms H. erinaceus identity in voucher specimens …

Determination Of Kratom Alkaloids In Botanical Products Using Multi-Criteria Lc–Ms Analysis, Mengliang Zhang

Oxford ICSB

Kratom (Mitragyna speciosa) is a botanical product widely sold in the United States as powders, capsules, tablets, gummies, and beverages. Natural kratom leaves primarily contain mitragynine (MG) as the dominant alkaloid. However, an increasing number of commercial products contain elevated levels of the more potent opioid alkaloid 7-hydroxymitragynine (7-OH) and the semi-synthetic compound mitragynine pseudoindoxyl (MGP). Reliable analytical identification of these compounds is critical for dietary supplement testing, regulatory monitoring, and public health protection. However, kratom matrices contain numerous structurally related alkaloids and isomeric compounds that complicate mass spectrometric identification and may lead to false positive assignments. The objective of …

Do Omega-3 Supplements Reduce Pain And Symptom Severity In Primary Dysmenorrhea, Kristen Werner

Liberty University Research Week

Background: Primary Dysmenorrhea is a gynecological condition that affects many women worldwide. It is characterized by painful menstrual cramping and can result in decreased quality of life. Omega 3 fatty acid supplements have been proposed as an alternative treatment method to reduce severity of dysmenorrhea.

Methods: The Prisma method was used to conduct an integrative literature review of Pub Med, EBSCO, and Google Scholar Databases.

Results: Omega 3 fatty acid supplementation has been shown to reduce dysmenorrhea pain and severity.

Conclusions: Omega 3 supplementation is a viable alternative to conventional treatments methods for dysmenorrhea. This is ideal for women who …

A Patient-Centered Framework For Overcoming Barriers In Tuberculosis Care, Owen Newman, Ethan Jerome, John Meade

Liberty University Research Week

Tuberculosis (TB) remains the world’s deadliest infectious disease, yet it is both preventable and curable. The disease disproportionately affects populations living in poverty, with significant global impact:

1.23 million deaths in 20241

10.7 million new infections globally1

80%+ of cases in low- and middle-income countries1

~50% of TB households face costs >20% of income1,2

This study argues that TB persists due to social determinants, such as poverty, malnutrition, and stigma, rather than medical limitations alone. We propose a three-domain framework that maps where standard medical care fails the individual: systemic infrastructure, economic burden, and psychosocial isolation. By addressing these three …

The Cost Of Cargo Preference: How Shipping Requirements Hinder Food Aid Efficiency, Grace Pattara

Liberty University Research Week

No abstract provided.

Genotype-Dependent Cardiac Responses To Caffeine: Acute Electrocardiographic Effects Across Cyp1a2 Gene Variants, Ethan Pedersen

Liberty University Research Week

It is estimated that approximately 70% of individuals worldwide consume caffeine daily. A plethora of genes contribute to caffeine metabolism, out of which CYP1A2 is responsible for 90%. Two prominent CYP1A2 alleles are *1A and *1F which metabolize caffeine at fast and slow rates respectively. Retrospective research has demonstrated *1F possessing individuals are at an increased risk for nonfatal myocardial infarction. However, the acute electrocardiographic and physiological cardiac responses to caffeine across a range of doses remain poorly characterized. The goal of the proposed study is to evaluate the physiological changes of the heart, using an ECG, in individuals who …

Vitamin D Relation To Bone Mineral Density In Female Athletes: Critically Appraised Topic, Baylee Klindworth

Liberty University Research Week

Background: Vitamin D is important for overall bone health, muscle function, and injury prevention, especially in female athletes who may be at risk for vitamin D deficiency that are limited to sunlight exposure, high training demands, and dietary intake. In young female athletes and adults, the relationship between vitamin D and bone mineral density (BMD) is not clear. The purpose of this critically appraised topic is to review current evidence on the relationship between vitamin D levels and bone health in female athletes and adults. Methods: Four cross-sectional studies were included: Fields et al., Brännström et al., Lim et al., …

Geographic Variation In Cardiometabolic And Nutrition-Related Health Indicators Across Rural Communities In Guatemala And Honduras, Grace Sibert

Liberty University Research Week

Chronic diseases and nutritional deficiencies are increasing public health concerns in rural and underserved communities in Central America, where limited access to preventive care and routine health screening contributes to undiagnosed risk. This study examined the prevalence and geographic distribution of cardiometabolic and nutrition-related health indicators across rural communities in Guatemala and Honduras. We conducted a cross-sectional analysis of community health screening data collected from 2021 and 2023–2025. Measurements included body mass index (BMI), blood glucose, hemoglobin, and blood pressure. Overweight was defined as BMI 25.0–29.9, obesity as BMI =30, elevated blood glucose as =140 mg/dL, hypertension as systolic =140 …

4-H Award Program

Warren C. Cowen Papers

Tarrant County 4-H award program for state 4-H winners Sandra Newton, Joe Spears, Tommy Lutes and Patricia Stephenson, November 13, 1961.

Icu Decision Tool Impact On Rebound Hyperglycemia, Daniel J. Donovan, Emily Highsmith, Sonya Khan, Michelle Horng

Advances in Cancer Education and Quality Improvement

Hyperglycemia, defined as a blood glucose level ≥180 mg/dL in the hospitalized patient, is linked to negative outcomes including longer hospital stays, increased infection risk, and higher morbidity and mortality rates. In addition to critically ill patients with diabetes, hyperglycemia can develop in individuals without diabetes due to factors such as steroid use, continuous tube feedings, and an elevated stress response. Patients who have uncontrolled hyperglycemia are often placed on continuous insulin infusions (CII), but rebound hyperglycemia frequently occurs after CII discontinuation if the maintenance insulin regimen (MIR) is insufficient. Implementation of a MIR decision support tool integrated within an …

Advancements In Extraction And Co-Extraction Of Botanicals For Standardization And Efficacy, Rory Coleman

Oxford ICSB

Historically, botanicals have served human health in traditional medicine and supplementation due to their bioactive components. Efficient, clean extractions and clinical validation have become fundamental technologies, rendering access to libraries of efficacious products. However, cost, regulatory status, and speed to market have kept many botanicals in single or simple form. Mixtures of such single botanical extracts often require large quantities for effect, influenced by chemical composition, concentration, and delivery format. During the extraction and concentration process, exogenous "bioenhancers," e.g. piperine or oil blends for hydrophilic molecules, often become a necessity, exasperating the problem.   Here, we will delve into the development …

2026 Conference Program, Georgia Southern University

GS4 Student Scholars Symposium

Conference Program

Yeast As A "Microbial Factory", Kaila Fuller, Betsy Jean Yakes

Oxford ICSB

Yeast are eukaryotic, single-celled microorganisms that are members of Kingdom Fungi, and in the world of dietary supplements, yeast qualify as a dietary ingredient as a botanical. During fermentation, yeast naturally produce byproducts that can be harvested, purified, and sold in a dietary supplement. Advances in biotechnology have allowed for genetic modification of yeast so that yeast can produce large quantities of native or non-native constituents during fermentation, effectively making yeast a “microbial factory” for various chemicals. Chemicals produced this way can qualify as a dietary ingredient as a constituent of a botanical. Relevant examples of past submitted notifications (public …

Probabilistic User Intent Modeling Based On Time-Window Gaze Analysis, John D. Hurwitz, Yaaseen Mahomed

Defensive Publications Series

ABSTRACT

A single-shot gaze vector often fails to accurately reflect user intent during multimodal queries due to saccadic noise, visual competition in dense environments, and the temporal lag between visual fixation and vocalization. This disclosure describes a method for multimodal query disambiguation using a temporal gaze buffer that maintains a rolling history of gaze vectors. After receiving a query, a probabilistic spatial-temporal heatmap can be generated from the buffered data. This heatmap represents attention density over a variable time window, which may be adjusted based on the query context or environmental classifications. To identify specific objects of interest, image frames …

Scientific Research In Cuba: A General Analysis With A Special Focus On Energy, Agriculture And Technology, Henri Dou, Pierre Fournie

International Journal of Islands Research

An analysis of science in Cuba is carried out using data from the OpenAlex database. Examples are developed: agriculture, rice, technology in relation to the current situation: national food supply, energy and medicine. The predominance of research in biology and medicine and the low commitment in the fields of agriculture, energy, medicinal plants and technology are highlighted. Various development schemes are proposed. The conclusion is that research must be directed towards strategic areas: food and energy, must be less dispersed and that technology must be better taken into account. Three proposals are made: the development of a chemical analysis platform …

Iron-Based Nanoparticles As Delivery Tools, Keykavous Parang, Rajesh Vadlapatla, Ajoy Koomer, Victoria Moran, Lanie Jackson, Amir Nasrolahi Shirazi

Pharmacy Faculty Articles and Research

Iron-based nanoparticles, particularly iron oxide nanostructures (IONPs), have emerged as versatile and clinically relevant platforms for drug delivery and theranostic applications. Among these, superparamagnetic iron oxide nanoparticles (SPIONs), including magnetite (Fe₃O₄) and maghemite (γ-Fe₂O₃), are the most extensively investigated due to their biocompatibility, magnetic responsiveness, and established safety profiles. Their unique superparamagnetic behavior enables external magnetic-field-guided targeting, magnetic resonance imaging (MRI) contrast enhancement, and magnetically triggered hyperthermia, enabling simultaneous diagnosis and therapy. Surface functionalization with polymers, silica, lipids, peptides, and biomolecules further improves colloidal stability, circulation time, targeting specificity, and controlled drug …

Advancing Caregiver Support In Community-Based Care: Advocacy, Resources, And Education Supporting Nicu Transition And Families With Complex Needs, Leah G. Rickard-Breeden

OTD Capstone Projects

This capstone project was completed in partnership with Nurses for Newborns (NFN), a nonprofit organization that is seeking to improve maternal and infant health outcomes across Middle Tennessee through free, in-home nursing visits. They provide education, health assessments, and connections to community resources for prenatal and postpartum mothers and their infants; specifically, those facing medical, emotional, or social barriers. The focus of this project was to create a comprehensive resource to support caregivers of infants through their transition from the NICU to home. A needs assessment revealed that families would benefit from additional support and resources to help bridge the …

Nutrition And Meal Preparation Programming And Development At E.L.I.'S House, Kara E. Nienhaus

OTD Capstone Projects

This doctoral capstone project was completed through a partnership with E.L.I.’s House in Franklin, Tennessee. E.L.I.’s House is a nonprofit organization that exists to help women and their children thrive after trauma. The desired outcome of this project was to create programming to provide education and life skills training to participants, and to develop manageable systems for grocery shopping and nutrition in the site handbook. Goals promoted occupational therapy-based skills such as meal preparation, nutrition management, cognitive flexibility, and task sequencing. The project involved creating a house recipe book with balanced meals, accessible information on basic nutritional needs for adults …

Cover And Contents, Editors Of Turkish Journal Of Agriculture And Forestry

Turkish Journal of Agriculture and Forestry

No abstract provided.

​Functional Characterization Of Stmtpsl Terpene Synthase-Like Genes And Their Role In Pathogen Resistance In Selaginella Tamariscina, Zhijie He, Bo Bi

Turkish Journal of Agriculture and Forestry

The biological activity and function of microbial terpene synthase-like genes from Selaginella tamariscina (StMTPSL) were investigated using molecular and biochemical approaches. After isolating and amplifying StMTPSL genes (StMTPSL1-StMTPSL6), both native and site-directed mutant forms were expressed in tobacco via Agrobacterium-mediated transformation. The resulting transgenic plants had increased expression of StMTPSL genes, enhanced monoterpene production (as confirmed by GC-MS), and significantly improved resistance to Pseudomonas syringae infection compared to nontransgenic controls. These results show that StMTPSL genes are functionally active in plants and contribute to pathogen resistance through elevated terpene biosynthesis. This study provides new insights into the role of MTPSL …

Effect Of Some Organic Fertilizers On Yield And Quality Of Olive Oil In Semiarid Conditions, İshak Bayyi̇ği̇t, Ebru Sakar

Turkish Journal of Agriculture and Forestry

This two-year field experiment evaluated the effects of different organic fertilizers on olive oil quality of the Gemlik cultivar grown under semiarid conditions in Mardin, Türkiye. Treatments of olive pomace (P1: 4, P2: 8, P3: 12 kg tree⁻¹), leonardite (L1: 1.5, L2: 3.0, L3: 4.5 kg tree⁻¹), and vermicompost (SG1: 3, SG2: 6, SG3: 9 kg tree⁻¹) were applied in a randomized complete block design with three replicates. Oils were analyzed for free acidity (FA), peroxide value, and phenolic profile using high-pressure liquid chromatography. FA ranged from 0.27% to 0.42% (as oleic acid), remaining well below the International Olive Council …

Revolutionizing Corporate Accountability: The La Oroya Case And The Right To A Healthy Environment In The Inter-American System, Teresa Jacques Valenzuela

University of Miami Inter-American Law Review

La Oroya v. Perú marks a pivotal moment in the evolution of Business and Human Rights and the Right to a Healthy Environment (R2HE) under the Inter-American legal framework. This paper examines the groundbreaking judgment of the Inter-American Court of Human Rights, which established new standards for state responsibility in regulating and supervising corporate activities to prevent environmental harm. By integrating principles of environmental law with human rights obligations, the case highlights the transformative potential of judicial action in addressing corporate accountability. While the judgment sets a precedent for advancing corporate responsibility, it exposes enduring challenges, including jurisdictional limitations, corporate …

Comparative Evaluation Of Curd Enriched With Essential Oils Derived From Dill, Caraway, And Cumin, Hafize Fidan, Toncho Kolev, Denis Dervish, Ivayla Dincheva, Ira Taneva, Serkan Yilmaz, Yusuf Şavşatli, Albena Stoyanova

Turkish Journal of Agriculture and Forestry

Curd cheese is a traditional dairy product that, in recent years, has increasingly been supplemented with various functional additives aimed at enhancing its aroma and flavor profile, improving overall quality, and extending shelf-life. The objective of the present study was to conduct a comparative evaluation of changes in selected physicochemical, microbiological, and sensory parameters of curd cheese enriched with 0.01% essential oils derived from dill (Anethum graveolens L.), cumin (Cuminum cyminum L.), and caraway (Carum carvi L.) fruits. Fatty acid profiling revealed a reduction in saturated fatty acids and an increase in oleic and linoleic acids in essential oil-enriched curds …

Silicon-Mediated Enhancement Of Wheat Tolerance To Drought Stress: A Comparative Study Of Antioxidant Activity, Photosynthesis, Secondary Metabolites, And Yield, Abida Kausar, Rida Yasmeen, Shahid Iqbal, Muhammad Bilal Hafeez, Asif Mukhtiar, Sadia Azeem, Ali Raza, Samreen Nazeer, Muhammad Zubair Akram, Muhammad Kamran, Fahd Rasul, Noreen Zahra

Turkish Journal of Agriculture and Forestry

Drought stress (DS) is a major constraint on optimal plant growth and yield. Agricultural researchers have been actively exploring fertilizers that can enhance crop production under DS conditions. Silicon (Si) application has emerged as a promising strategy for managing DS in various crops. This study investigated the potential of Si soil drenching to mitigate the adverse effects of varying levels of DS (at 100%, 70%, and 40% field capacity) in wheat. Two varieties (Ujala-2016 and FSD-2008) were used to evaluate the influence of Si (2.5 mM) on antioxidant activity, oxidative burst, secondary metabolites, growth, and yield. The results indicated that …

Quantifying Sleep Wake Rhythms In The Hospital Environment With Digital Technologies, Carsten Skarke, Nadim El Jamal, Michael V. Genuardi, Thomas G. Brooks, Antonijo Mrčela, Nicholas F. Lahens, Makayla Cordoza, Sean Sarles, Amarachi Mbadugha, Dineth R. Karunamuni, Shikhar Gupta, Charles J. Bae, Amita Sehgal, Thomas P. Cappola, Jacob T. Gutsche, Pavan Atluri, Nimesh D. Desai, Michael A. Acker, Gregory R. Grant, Richard J. Schwab, Ilene M. Rosen, Garret A. Fitzgerald

Division of Cardiology Faculty Papers

Postoperative clinical care is prone to circadian desynchronization that may influence health outcomes. In an exploratory, feasibility-oriented and signal-exploration effort, we collected 1.8 million data points using 11 remote sensors during preoperative, in-hospital and post-discharge settings in 13 elective cardiac surgery patients (5.2% enrolled from 252 screened). We found that room traffic continued during nighttime with ≥1 visit/h. Sound levels exceeded the recommended 45 dBA threshold (51.9 ± 3.3 vs. 48.3 ± 4.2 dBA during nighttime). Brightness dropped at night (89.9 ± 87.7 to 3.7 ± 9.8 lux), but bright light exposures occurred. Ambient room temperature lacked sleep-inducing diurnal variability. …