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The Hope College Department Of Biology: The First 50+ Years, Christopher C. Barney

Faculty Publications

The Hope College Department of Biology was founded in 1899 with the appointment of the first Professor of Biology at Hope, Samuel Mast. During the first 50+ years of the Biology Department, there were eight total faculty members in the department, including Frances Koeman, the first female faculty member in the natural sciences. Four faculty members, Mast, Frank Patterson, Oscar Thompson, and Teunis Vergeer were primarily responsible for developing the department’s curriculum and programs, with Mast and Vergeer also carrying out published research. The department was housed primarily in Van Raalte Hall and the Science Building (now Lubbers Hall) for …

A Holistic Christian Perspective On Wellness For College Students - A Qualitative Analysis, Shari L. Jurgens, Deb Majewski, Jessica Clevering

Movement and Being: The Journal of the Christian Society for Kinesiology, Leisure and Sports Studies

Aim: This study sought to explore the impact of a Christ-centered, holistic wellness course on college-aged students’ understanding of key wellness principles. The goal was to gain insight into how students comprehend and apply these principles considering their spiritual and personal development.

Background: Wellness education for undergraduate students is both timely and essential, especially within Christian higher education, where nurturing the whole person is a core value. A common misconception is that wellness pertains only to physical and mental health. However, Scripture affirms that human flourishing involves a harmony of body, mind, and spirit. A holistic, biblically informed approach to …

The Critical Pediatric Obesity Window: Pre-Pubertal Metabolic Disease And The Fallacy Of Delayed Intervention., Matthew Lindquist, Brooke Sweeney

Manuscripts, Articles, Book Chapters and Other Papers

Despite increasing recognition of pediatric obesity as a chronic disease, many clinicians continue to rely on "watchful waiting," assuming pubertal growth will mitigate excess weight and metabolic risk. Current evidence contradicts this approach. Children under 12 years of age with obesity frequently demonstrate clinically significant metabolic disease, including insulin resistance, dyslipidemia, dysglycemia, and metabolic dysfunction-associated steatotic liver disease (MASLD), often before symptoms emerge. Puberty does not reverse these processes; rather, physiologic pubertal insulin resistance amplifies preexisting metabolic dysfunction and accelerates disease progression. Delayed intervention allows potentially irreversible injury during a critical period of metabolic plasticity. This article reviews contemporary biologic …

Insurance Type And Menopausal Hormone Therapy Use Among Us Women, Arina Chesnokova, Sunni Mumford, Allison Schachter, Rebecca Hamm, Scott Lorch, Matthew Klebanoff, Sarah Lindley, Erika Harness, Makeba Williams, Marilyn Schapira

Student Papers, Posters & Projects

IMPORTANCE: Access to menopausal hormone therapy (MHT) in the US remains low. Understanding whether insurance type is associated with MHT underuse and racial disparities in menopausal care is critical for designing interventions that increase evidence-based and equitable menopause care.

OBJECTIVE: To examine whether Medicaid compared with private insurance is associated with lower MHT use among US women. A secondary objective explored the degree that payer type is associated with observed racial differences in MHT use.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used the 2013-2014, 2015-2016, and 2017-2020 cycles of the National Health and Nutrition Examination Survey (NHANES) to identify …

Esophageal Stricture Post Congenital Tracheoesophageal Fistula Repair, Zaid A. Zaid, Momtaz Al-Nima

Iraqi Postgraduate Medical Journal

Background: It’s a narrowing of > 50% of the esophagus lumen or as a narrowing detected on a contrast study , or at esophagostomy in combination with symptomsTracheoesophageal fistula (TEF) is a relatively rare congenital anomaly occurring in one in 2500-3000 live births (3)Moreover, the life expectancy of the patients without proper treatment may be measured in weeksAim of study: evaluation of the demographics, surgical details, and postoperative outcomes of pediatric patients undergoing surgery for Tracheoesophageal Fistula (TEF) repair.Methods: The study was conducted at Pediatric Teaching Hospital/Medical City from December, 2022, to November , 2023. A total of 35 cases post …

Evaluation Of Peripheral Nerves In Patients With Acromegaly By Electrodiagnostic Study, Taiseer Saad Musa, Farqad Bader Hamdan, Abbas Mahdi Rahmah

Iraqi Postgraduate Medical Journal

Background: Acromegaly is a rare multisystem disorder caused by excess growth hormone (GH) and insulin-like growth factor 1 (IGF-1), typically from a pituitary somatotroph adenoma. Neurological complications, particularly peripheral neuropathies, are common but under-investigated.Objectives: To evaluate peripheral nerve involvement in Iraqi patients with acromegaly and assess the impact of IGF-1 levels, disease duration, adenoma size, and other clinical variables on nerve function.Methods: A cross-sectional study included 41 acromegalic patients (≥25 years) who underwent detailed neurophysiological testing. Patients were classified as metabolically controlled or uncontrolled based on IGF-1 levels.Results: IGF-1 and GH levels were significantly lower in the controlled group (p<0.001), while other clinical variables showed no significant differences. Neurophysiological findings revealed significantly reduced sensory and motor amplitudes, prolonged latencies, and slower conduction velocities in the uncontrolled group. IGF-1 levels correlated positively with sensory and motor latencies and negatively with conduction velocities and CMAP amplitudes. Larger adenoma size and presence of diabetes were also associated with worse nerve parameters. Deep X-ray therapy and surgical excision showed beneficial associations with median nerve conduction velocity.Conclusion: Peripheral nerve dysfunction, including carpal tunnel syndrome and polyneuropathy, is more severe in metabolically uncontrolled acromegaly. Macroadenomas and poor biochemical control are linked with worse neurophysiological outcomes.

Sharing The Voices Of Latine Students: Their Experiences Of Community, Belonging And Joy In A Suburban Public High School, Ashley Acosta-Meyers

School of Education and Leadership Student Capstone Theses and Dissertations

This qualitative phenological and ethnographic study explored how seven Latine high school students in a suburban public high school defined and experienced community, belonging, and joy, asking what school spaces, experiences, and practices build or diminish these three concepts. Data was collected through four interview sessions per participant, reflective journaling, and three culturally and linguistically responsive walkthrough observations, and were analyzed through layered linguistic, narrative, and thematic coding. Findings showed that belonging and joy were tied to specific spaces rather than felt evenly across the school day. Institutional fairness shaped belonging as much as any relationship. Latine identity was contested, …

Impact Of Baseline Cognition On Dual-Task Performance: Tracking Verbal Accuracy And Fluency In Adults At Risk For Alzheimer’S Disease, Rebecca Nicole Frederichs

Graduate Theses and Dissertations

Alzheimer’s Disease (AD) is increasing in prevalence as life expectancy continues to rise, highlighting the need for sensitive measures to detect early cognitive changes. This study examined the effects of baseline cognitive status on dual-task performance over time, in terms of dual-task cost, verbal fluency, and verbal accuracy in older adults at risk for AD. This study utilized a quantitative secondary analysis of the longitudinal dataset, the Digital, Cognitive, Multi-Domain Alzheimer Risk Velocity (DC-MARVel) study (Gray et al., 2022). Participants were categorized into low, medium, or high cognitive tertiles based on baseline Repeatable Battery for the Assessment of Neuropsychological Status …

Seasonality Of Bovine Respiratory Disease Incidence, Nasal Temperatures, And The Nasal Microbiome In Receiving Beef Cattle: Understanding The Risk Of The Bovine Respiratory Disease Complex, Robin Ashley Cheek

Graduate Theses and Dissertations

Bovine respiratory disease (BRD) has persistently been the leading cause of morbidity of beef cattle in the United States. Season has been directly associated with respiratory disease incidence and is likely a proxy for weather conditions, which vary by geographical location. The nose is one of the first points of contact between the outside environment and inside the body. The nasal microbiome and its relationship with BRD have been heavily studied within beef cattle, but there are not yet any studies to determine if the environment within the nasal cavity has a role to play in this mechanism. This dissertation …

Evaluation Of Metabolizable Energy And Phosphorus Availability In Conventional And Fractionated Dry-Grind Corn Co-Products For Poultry, Luke Parisi

Graduate Theses and Dissertations

The purpose of this research was to determine the availability of energy and phosphorous (P) in dry-grind corn co-products in chickens was assessed. In the first objective, the determination of energy availability, both a precision-fed rooster assay and an ad libitum fed broiler chicken assay were used in order to elucidate energy availability in corn co-products. There were 8 samples of corn fermented protein (CFP) and 2 samples of conventional distillers dried grains with solubles (CDDGS) evaluated for metabolizable energy (ME). The CFP contained a mean CP and crude fat of 55 and 3.7% (DM basis), respectively, compared with 30 …

Potassium Fertilization Timing And Critical Stalk Potassium Concentration As Tools To Improve Corn Production, Gabriela Andrade Leite Mengez

Graduate Theses and Dissertations

Potassium (K) is a common yield-limiting nutrient in Mid-Southern U.S. corn (Zea mays L.) production, emphasizing the importance of effective diagnostic tools to support fertilizer decision-making. This study integrated two approaches to improve K management in irrigated corn systems: (i) evaluating K fertilization timing to identify in-season opportunities for correcting K deficiency, and (ii) developing a corn stalk-based diagnostic test to assess end-of-season K and nitrate-nitrogen (NO₃-N) status and fertilizer adequacy. Seven (2024-2025) and eight (2023-2024) field trials were conducted across Arkansas for the K application timing and stalk testing studies, respectively. For the K timing study, fertilizer-K (112 kg …

Organic-Complexed Or Inorganic Trace Mineral Tub Supplementation: Impacts On Productivity And Reproductive Outcomes In Beef Cows And Heifers, Jacy Riddle

Graduate Theses and Dissertations

The objective of these experiments was to investigate the effects of organic-complexed or inorganic trace minerals (copper, cobalt, manganese, and zinc) on cow reproductive performance, suckling calf growth, as well as heifer development and reproductive outcomes utilizing free-choice tub supplementation. In lactating cows, treatments consisted of molasses-based tub supplementation containing either complexed or inorganic trace minerals, with an additional pre-breeding drench administered only to cows receiving complexed minerals. The drench contained complexed or organic copper, cobalt, manganese, and zinc. Supplementation began approximately 6 weeks prior to fixed-timed artificial insemination (FTAI) and continued until bull removal (d 105). In weaned replacement …

Evaluating Variety- And Market-Class-Specific Effects Of Dietary Pulses On Human Health, Jiayu Tang

Department of Food Science and Technology: Dissertations, Theses, and Student Research

While pulses are globally recognized for their high levels of dietary fibers, protein, and polyphenols, research often focuses on characterizing the physiological effects of a single variety. This approach overlooks the substantial genetic and compositional diversity that exists across pulse varieties and individual market classes, which can differ extensively in nutrient content and structure. These compositional differences have the potential to produce distinct physiological and microbial responses in humans, yet variety- and market-class-specific effects remain poorly characterized.

This thesis uses two complementary research methodologies to investigate the health-relevant effects of different pulse varieties and market classes, providing foundational knowledge to …

Evaluating Relationships Between Immunometabolism And Excess Adiposity Using Anthropometric And Body Composition Measurements, Corina Grimaldo

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Metabolic dysfunction is a key contributor to the development of chronic disease and is associated with excessive adiposity. Though body mass index (BMI) is a common screening tool used to identify possible metabolic dysfunction, it does not consider fat distribution. Other tools are needed to assess body composition and determine fat distribution. In recent studies, it has been suggested that alterations in metabolic processes may occur prior to a clinical diagnosis, and the combination of body composition and blood-based markers can help identify those early changes. The overall objective of this study is to identify low-cost indicators of metabolic dysregulation …

Current Practices And Variations Among Pediatric Severe Asthma Programs In The United States-The North American Severe Pediatric Asthma Consortium., Kristina Gaietto, Nadia Krupp, Avani V. Shah, Erhan Ararat, Samantha H. Averill, Sachin Baxi, Matejka Cernelc-Kohan, Jeffrey M. Chambliss, Heather De Keyser, Monica Federico, Bob Geng, Akilah A. Jefferson, Parisa Kaviany, Lila C. Kertz, Kirsten Kloepfer, Allyson Larkin, Sydney Leibel, Tanya Martinez-Fernandez, Samira Naime, Robert D. Pesek, Dinesh K. Pillai, Deepa Rastogi, Katherine Rivera-Spoljaric, Kristie R. Ross, Franziska J. Rosser, Tregony C. Simoneau, Jade Tam-Williams, Kelan G. Tantisira, William Anderson, Jonathan M. Gaffin, Theresa W. Guilbert, Erick Forno

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Severe and difficult to treat asthma in children is a complex condition causing significant morbidity and associated healthcare costs. While treatment guidelines exist for severe asthma, optimal treatment approaches for the pediatric population are less well established. Furthermore, best practices regarding real world management and implementation of guidelines for the severe pediatric asthma population are lacking. In order to provide care for this population, institutions around the United States have developed multidisciplinary severe pediatric asthma programs (SPAPs). In recent years, the North American Severe Pediatric Asthma Consortium (NASPAC) was established as a mechanism for SPAPs to collaborate and share …

Quality Improvement Project To Reduce Wait Time For Pediatric Gastrointestinal Procedures., Jennifer Colombo, Nicholas Clark, Laura E. Shroyer, Dustin J. Hahn, Jonathan Patterson, Kenneth Sam

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Delays in care can lead to poor health outcomes and suboptimal patient and family experiences. We aimed to reduce the average wait time for gastrointestinal endoscopic procedures (procedure request to procedure completion) from 145 to 15 days (a 90% reduction) within 4 months (November 2023 to March 2024).

METHODS: A3 problem-solving methodology was used. The primary intervention was a multiday, multidisciplinary improvement workshop. Outcome measures included (1) procedure request date to procedure completion date, and (2) favorable patient satisfaction score for timeliness of access to care. Process measures included (1) procedure request date to date procedure scheduled by staff, …

How To Tell A True Food Allergy From An Intolerance, Sarah Gubara, Aarti Pandya

Pediatrics in Practice: A CME Podcast

This episode explains the key history elements and symptom timeline that differentiate an IgE-mediated food allergy from an intolerance or sensitivity, so clinicians and parents can make safer, evidence-based decisions. Aarti Pandya, MD, Medical Director of the Food Allergy Center at Children’s Mercy, reviews symptom patterns, timing and red flags for anaphylaxis. Learn about food allergy testing, IgE-mediated food allergy, anaphylaxis action plan, epinephrine auto-injector, food intolerance and when testing is truly warranted.

Click here to stream the podcast episode.

Nh Ece Research Consortium Research & Evaluation Stakeholder Map, Jess Carson, Evan England, Lisa Bauer

New Hampshire Early Care and Education Research Consortium

New Hampshire's early care and education (ECE) ecosystem is complex and includes a broad, dynamic community of people and organizations who contribute to and rely upon ECE research. This visual stakeholder "map" documents the organizations that contribute to research and evaluation in NH ECE. These maps rely on contributions, updates, and refinements from the field and are meant to be a shared resource reflecting the complexity and partnerships in New Hampshire's ECE ecosystem.

Animal Science Research And Extension Report 2026 (Complete Report), Department Of Animal Science

Animal Science Research Report 2026

This is the 2026 Animal Science and Extension Report. This highlights the research being generated within the department over the previous year.

Evaluating Fungicide Programs For Grapevine Disease Management And Fungicide Sensitivity Monitoring, Abraham Ahumada

Master's Theses

Grapevine diseases, such as powdery mildew and Botrytis bunch rot, require repeated fungicide applications to maintain fruit quality and reduce yield losses. However, fungicide performance can vary among products, application programs, disease pressure, and pathogen sensitivity. This thesis evaluated fungicide programs for control of powdery mildew in ‘Chardonnay’ grapes and assessed fungicide sensitivity of Botrytis cinerea isolates collected from California vineyards.

Powdery mildew, caused by the fungal pathogen Erysiphe necator, is a major threat to the production of Vitis vinifera grapes worldwide. Because powdery mildew management relies heavily on fungicide applications, field evaluations are needed to compare the efficacy …

Has Plant Domestication Compromised Plant Defensive Chemistry? Aphid Induced Stress In Tomatoes, Nhi Do, Satinderpal Kaur, Minxing Zhu, Esther N. Ngumbi

MICRO-CCS student projects

Tomato plants have natural defensive mechanisms.

Direct: Phenolics are secondary metabolites that can protect the plant by intoxicating the herbivores and/or producing strong repulsive odors.

Indirect: VOCs, Volatile Organic Chemicals, are gas phase signals that attract the predators of the attacking herbivore to the plant.

Domestication of plants may chemically alter these defenses by prioritizing fruit production over defensive traits.

We hypothesize that wild/ancient tomato plants would have a greater quantity of volatiles and increased concentration of leaf total phenolics compared to cultivated tomatoes during aphid herbivory.

Addressing Hypertension Medication Non-Adherence Through The Use Of Reminders And Morisky Medication Adherence Scale In Adults Diagnosed Within The Past Year In A Rural Primary Care Clinic, Amanda M. Weaver

Doctor of Nursing Practice Projects

Background: Adherence to antihypertensive medications is essential for decreasing long-term consequences of uncontrolled hypertension, including stroke, kidney failure, and cardiovascular diseases. However, nonadherence is a widespread problem among patients diagnosed with hypertension. In patients who have been diagnosed with hypertension in the past year, more than half stop taking their medications. Mobile health interventions, such as text message or telephone reminders, are a low-cost way to improve medication adherence.

Purpose: The purpose of this Doctor of Nursing Practice project is to examine how a weekly text message or telephone reminder impacts medication adherence among patients taking antihypertensives in a rural …

Decoration Of Lactic Acid Bacterium By Exploiting In Vitro Sortase A Transpeptidase, Faisal Hamd Alqhtani

Graduate Theses and Dissertations

Attaching a drug module to the surface of lactic acid bacteria was the main aim of this dissertation, and it was achieved. By using the Sortase A mechanism, the drug module (green fluorescent protein fused to the LPETG motif) was anchored to the LAB surface. To reach the final results, this dissertation will describe the process that I undertake to achieve the end goal. Modifying media, producing pure enzymes with less impurity, and reducing the protease activity in E. coli BL21 were all described in this five-chapter dissertation. Keywords: drug delivery, lactic acid bacteria, green fluorescent protein, sortase A, fusion …

Efficacy Of Volume-Based Enteral Feeding Compared With Standard Rate-Based Enteral Feeding, Tashia Stevens Rn, Kelly St Jean Rn, Darah Thomas Rn

Nurse Residency

Is volume-based enteral feeding more effective than standard rate-based enteral feeding in achieving nutritional goals and improving clinical outcomes in critically ill patients?

Harnessing Nitrogen Fixing Plants For A Bio-Solar Nitrogen Economy, Taufiq Nawaz, Liping Gu, James Young, Riffat Latif, Mazhar Sher, Lan Xu, Shah Fahad, Ruanbao Zhou

Natural Resource Management Faculty Publications

The fossil fuel–driven chemosynthesis of ammonia for nitrogen fertilizers is a major contributor to global greenhouse gas emissions, releasing approximately 1130 million metric tons (MMT) of CO₂-equivalent annually. In addition, the extensive use of synthetic nitrogen fertilizers (≈108 MMT annually) results in substantial emissions of nitrous oxide (N₂O), while nearly 50% of applied nitrogen is lost through leaching and runoff, leading to widespread nitrate pollution and ecosystem degradation. In contrast, solar-powered biological nitrogen fixation (BNF) by nitrogen-fixing plants offers a sustainable alternative that supports agricultural productivity and healthy ecosystem resilience. BNF by leguminous and non-leguminous plants …

Integrating Cover Crops To Enhance Abaca (Musa Textilis Nee) Production In Leyte, East-Central Philippines, Janet Moriles Miller, David Clay, S. A. Clay, D. E. Clay, R. Armecin

Agronomy, Horticulture and Plant Science Faculty Publications

Abaca (Musa textilis Nee) is a fiber crop, closely related to banana (Musa sp.). However, it requires 15–18 months from transplanting to first harvest, leaving the soil between plants vulnerable to erosion or weed infestation. Integrating cover crops into abaca plantations may help mitigate these issues. This study aimed to examine the influence of diverse cover crop species on abaca production during its early and late growth phases. Two experiments were conducted to assess the impacts of cover crops on abaca. First, the impact of forage peanut (Arachis pintoi) and koronivia grass (Brachiaria humidicola) …

Electronic Resource Updates - 2026 Q2, Brigitte Galauner, Gregg Harris

Electronic Resources Quarterly Updates

No abstract provided.

Reclaiming The Sacred Science Of Garbha Samskara: The Adi Shaiva Tradition's Vision Of Conscious Conception And Prenatal Care, Rani Muthukrishnan

All Faculty Scholarship (Archived)

This paper examines Garbha Samskara practices described in the Garbha Upanishad within the Adi Shaiva tradition, exploring how ancient prenatal sciences cultivated cognitive development and spiritual consciousness in children. Drawing on original Sanskrit verses, the eNpregnancy program revived by Supreme Pontiff of Hinduism Sri Nithyananda Paramashivam (SPH), Akashic record readings, historical accounts of royal women who raised enlightened children, and testimonies of parents participating in the eNpregnancy program in modern times, the study demonstrates that pre-colonial Indian societies possessed advanced understandings of fetal consciousness and maternal–fetal bonding. It argues that modern Western educational paradigms and the contemporary expectations imposed on …

Characteristics Of Intensive Care Unit Registries - Findings From The Global Registry Icu Datasets (Grid) Survey, Luigi Pisani, Paola Lecce, Cornelius Sendagire, Vrindha Pari, Carlo Olivieri, Rabiul Uddin, Diptesh Aryal, Priyantha Athapattu, Sean Bagshaw, Wangari Siika

Anaesthesiology, East Africa

Background: Intensive care unit registries, which aim to improve the quality of intensive care unit care through benchmarking and quality improvement initiatives, are active worldwide, with considerable dishomogeneity. We aimed to map core datasets, additional variables, and research activities of these registries.

Methods: A cross-sectional survey was disseminated to registry leads between October 2023 and June 2024. The survey was structured into four main topics: registry characteristics and coverage, core dataset features, additional modules, and registry-enabled research.

Results: Leads of 34/42 national registries responded (response rate 81%), covering 3,337 intensive care units, with a larger representation from …

Resilience In Restoration: Investigating The Thermal Tolerance Of Galapagos Corals During El Niño, Ava Besecker

Capstone Projects and Master's Theses

Rising sea surface temperatures have driven widespread coral bleaching and mortality, yet some corals persist through repeated marine heatwaves. In the Eastern Tropical Pacific (ETP), extreme conditions provide a natural laboratory for studying resilience, and some corals have persisted even after declines due to repeat El Niño-driven mortality events. This study investigates drivers of coral resilience by fate-tracking three dominant genera in the ETP at a restoration site on Isabela Island, Galapagos during a natural warming event. I evaluated how algal symbiont community composition, genetic lineage, temperature, and site-specific environmental conditions interacted to shape coral growth, bleaching, and survival before, …