Digital Commons Network^™

In Silico Exploration Of Alstonia Scholaris Secondary Metabolites As Antioxidant: Molecular Docking With Key Enzymes And Toxicity Prediction, Arifa Rizqi Nafisa, Anggiresti Kinasih, Muhammad Luqman Hakim, Arif Nur Muhammad Ansori

Makara Journal of Science

Degenerative diseases associated with oxidative stress necessitate the development of effective antioxidant therapies. Alstonia scholaris, a medicinal plant known for its diverse pharmacological properties, was investigated for its antioxidant potential using computational approaches. This study employed molecular docking to evaluate the interactions between bioactive compounds from Alstonia scholaris and key antioxidant target proteins, including lipoxygenase, CYP2C9, NADPH oxidase, and bovine serum albumin. Pharmacokinetic analyses based on Lipinski’s Rule of Five, along with toxicity assessments, were conducted to evaluate the compounds’ drug-likeness and safety profiles. The results demonstrated that (+)-Dicentrine exhibited the strongest and most stable binding affinity toward lipoxygenase …

Differential Gene Expression Of Ethylene Biosynthesis And Signaling Associated With Climacteric Behaviors In Indonesian Melon, Vida Rahma Latifah, Adib Fakhruddin Yusuf, Karso Suryo Putro, Dian Sartika, Anjar Tri Wibowo, Awik Puji Dyah Nurhayati, Karlia Meitha, Miftahudin Miftahudin, Budi Setiadi Daryono

Makara Journal of Science

Fruit ripening in melon (Cucumis melo L.) is a complex developmental process that is characterized by the coexistence of climacteric and non-climacteric varieties within the same species. This study characterized the ripening behavior of four local Indonesian melon cultivars (“Melona”, “GMP”, “Tacapa Gold”, and “Kinaya”) by integrating morphophysio-logical traits with transcriptional expression analysis of ethylene biosynthesis (CmACS, CmACO) and signaling (CmATH, CmEREBP) genes. The results revealed a strong agreement between the phenotypic traits and molecular regulation. “Melona” and “GMP” exhibited a strong climacteric profile, which was characterized by natural fruit abscission, sweet aroma …

Impact Of Disturbances On Butterfly Communities At The Forest Edge Of Bukit Mas Village, North Sumatra, Indonesia, Nurhayati Nurhayati, Mufti Petala Patria, Nurul Winarni, Fairuz Husna

Makara Journal of Science

Biotic homogenization can negatively impact ecosystem function and stability, reducing species diversity and interac-tions. Although deforestation has declined in Gunung Leuser National Park since 2011, associated pressures still operate at various places within the park, possibly leading to biotic homogenization. This study looked into the differences in butterfly diversity under three habitat types to understand their responses to various levels of disturbance, including en-vironmental factors. This research was carried out in September 2023 at the forest edge of the Bukit Mas Village, North Sumatra. We used the Point Count method; observations were made twice in the morning (08.00–12.00 h) and …

Network Pharmacology Of A Decaffeinated Green Coffee–Turmeric Combination: Potential Therapeutic Activity Against Hypertension And Diabetes Mellitus, Feri Eko Hermanto, Mohammad Saifur Rohman, Victor Alvianoes Guterez Hose, Mifetika Lukitasari, Dwi Adi Nugroho, Nashi Widodo, Inggita Kusumastuty

Makara Journal of Science

Decaffeinated green coffee and turmeric are recognized for their protective effects against hypertension (HTN) and diabetes mellitus (DM). Combining them into a functional drink, green coffee and turmeric (GCT), offers potential health benefits for managing these conditions. This study explored the bioactivity of GCT in HTN and DM through network biology, identifying intersecting protein targets and their roles in inflammation and glucose metabolism. Key proteins identified were AKT1, CCL2, CXCL8, IL-1β, and IL18. Molecular docking revealed that GCT compounds, particularly Cafestol, Chlorogenic Acid, Kahweol, Curcumin, and Desmethoxycurcumin, interacted strongly with AKT1 at its allosteric site, potentially inhibiting its activity. However, …

Lignin Valorization To Phenolic Compounds Over Metal Oxide-Modified Hierarchical Zsm-5 Zeolites Derived From Indonesian Minerals, Arnia Putri Pratama, Iman Abdullah, Yuni Krisyuningsih Krisnandi

Makara Journal of Science

Lignin, a key component of lignocellulosic biomass, offers significant potential as a renewable raw material for the sustainable production of aromatic chemicals. To investigate its heterogeneous catalytic depolymerization, benzyl phenyl ether (BPE) was used as a model compound. Hierarchical ZSM-5 catalysts were synthesized and modified with metal oxides (NiO and CuO). Belitung kaolin and Bayat natural zeolite, natural minerals from Indonesia, were used as silica and alumina sources to synthesize hierarchical ZSM-5 zeolite (labeled as ZSM-5N), which was compared with hierarchical ZSM-5 synthesized using pro-analysis precursors (labeled as ZSM-5S). Comprehensive physicochemical characterization using FTIR, XRD, BET, XRF, SEM-EDX, and NH₃-TPD …

Evaluating Peak Metamorphic Conditions Of The Kyanite-Bearing Rocks At Willis Mountain, Virginia, Usa, Emma J. Hunt, Peter Horvath, Connor R. Gregory, Jade D. Sabillon, Ethan H. Watson

Earth and Environmental Sciences Publications

Willis Mountain, near Dillwyn in central Virginia, is the world’s largest kyanite deposit located in the Chopawamsic Fm. of the Piedmont province. However, little is known about the temperature and pressure conditions under which the kyanite deposit and its surrounding rocks formed, compared with similar-aged rocks in the Blue Ridge province to the southwest. Willis Mountain is composed of kyanite-bearing muscovite schists to kyanite quartzites which contain up to 55% kyanite. The following methods were used to evaluate the metamorphic conditions, with multiple calibrations for each: phase equilibrium modelling; trace element thermometry (titanium in quartz and zirconium in rutile); garnet-biotite …

Home On The Range: Where Deer And Antelope Compete With Feral Horses For Limited Resources, Katelyn Davies, Hannah B. Klugman, Kathryn A. Schoenecker, David C. Stoner

All Current Publications

Given projections for continued drought conditions in the West, a better understanding of how native wildlife respond to competition with feral horses will be critical for developing effective conservation programs in the future. This fact sheet provides information on feral horses and presents study data comparing their use of water resources with that of native wildlife.

Green Finance’S Role In Bank Risk: Empirical Evidence From The Emerging Economy, Viverita Viverita, Dwi Nastiti Danarsari, Ratih Dyah Kusumastuti, Ruhaini Muda

Journal of Environmental Science and Sustainable Development

Indonesia’s Financial Services Authority (OJK)’s sustainable finance roadmap, phases I and II, primarily aims to facilitate sustainable development by integrating economic, social, and environmental considerations into financial policies. A special objective is to promote the development of green financial products and services. This policy allows banks to mitigate reputational and regulatory challenges. Nevertheless, the prompt implementation of green credit may entail transition risks, such as policy adjustment costs. A limited body of research examines the direct relationship between green finance and bank risk, particularly in the context of sustainability mandates. This study analyzes the influence of green finance on banking …

A Fate-And-Transport Model For Diclofenac From Wastewater Treatment Plants To The Diyala–Tigris Rivers, Baghdad, Iraq, Mohammed A. Al-Ameri, Ghyda Y. Al Kindi, Noor S. Mahdi

Engineering and Technology Journal

Diclofenac is a widely used non-steroidal anti-inflammatory drug that is incompletely removed by conventional wastewater treatment. This study evaluates its fate and transport from consumption and excretion, through the three Al-Rustamiyah wastewater treatment plant (WWTP) units in Baghdad, to the Diyala River, the Tigris River, and the Al-Tuwaitha drinking-water intake. Discrete ``grab'' samples were collected during 12–14 November 2020 from WWTP influent and effluent streams and from river and intake sites. Diyala River concentrations ranged from 0.094 to 2.184 μg/L. At the Tigris confluence, diclofenac was 0.052 μg/L; the two immediate downstream measurements were below 0.01 μg/L …

Geotechnical Enhancement Of Noncohesive Coal Mine Overburden Using Microbially Induced Calcite Precipitation And Fly Ash Stabilization For Sustainable Pavement Applications, Atul Gautam, Laxmikant Yadu

Journal of Sustainable Mining

The majority of the waste generated from opencast mining, termed as overburden (OB), is dumped adjacent to the mine boundary and poses long-term stability issues. Various studies have been carried out to assess the risk of dump slope failure, and treatment strategies have been accordingly recommended to strengthen this OB dump. However, scant works are reported to sustainably utilize this OB for construction works. This study aims to quantify the performance of stabilized noncohesive coal mine OB collected from Gondegaon opencast mine (OCM) in India. Stabilization was achieved using two techniques, namely microbially induced calcite precipitation (MICP) through Sporosarcina pasteurii …

Evaluating Atmospheric Nox In The Marine Boundary Layer Near Tampa Bay, Ben Lloyd '25, Anson Kirsch, Samuel Irvine, Yasin Elshorbany, James Ivey

Student Research

Nitrogen oxides (NOX), including nitric oxide (NO) and nitrogen dioxide (NO₂), are atmospheric constituents that can contribute to nitrate deposition in seawater. Since nitrate availability can influence marine ecosystems, understanding atmospheric nitrogen inputs is important for characterizing nitrogen cycling in coastal environments. This dataset contains atmospheric NO and NO₂ measurements collected from July 5–6, 2023, in the marine boundary layer near Tampa Bay, Florida, at the University of South Florida St. Petersburg campus using a Teledyne T200UP Analyzer.

The dataset provides observations of atmospheric nitrogen oxide concentrations that can be compared with measurements of nitrate in rainwater and seawater to …

Not Merely A Workaround: Theorizing Asynchronous Math Talks As A Robust Instructional Routine For Visible Thinking, Participation, And Engagement In Mathematics Teacher Education, Simon Byeonguk Han

Dissertations and Theses

The sudden global shift due to COVID-19 accelerated the need for a better understanding of mathematics learning and teaching in an asynchronous format. Also, despite the popular use of mathematics instructional routines in mathematics classrooms, the field of mathematics education research has very limited empirical studies on instructional routines. This dissertation addresses this by examining Asynchronous Math Talks (AMTs), a structured instructional routine adapted from Number Talks. The central goal of this research is to develop and theorize AMTs not merely as an online workaround, but as a robust instructional model that leverages the unique affordances of digital platforms to …

When Three Points Aren't Enough: Parameter Estimation In Newton's Law Of Cooling, Alberto A. Condori, Cara D. Brooks, Madeline R. Goldberg

CODEE Journal

We begin with a paradoxical three-point problem where the standard parameter estimation formula fails because temperature data must satisfy a concavity condition reflecting Newton's Law of Cooling's exponential structure. Although a closed-form solution for A exists for equally-spaced measurements, high sensitivity to error motivates the use of overdetermined systems with many measurements. The "profiling over A" technique transforms this three-parameter nonlinear problem into a sequence of simple linear regressions, providing computational efficiency and conceptual transparency. This approach can be generalized to many parameter estimation problems in science and engineering, making it a valuable tool for undergraduates interested in applied mathematics. …

Ai In Higher Education: Some Notes From The Front, Debra Rienstra

University Faculty Publications and Creative Works

We’re four weeks into the semester now. This past summer, our university unveiled a campus-wide AI policy that exhorts students and faculty to use discernment and tries to lay out some rules about security. Meanwhile, we have purchased a campus-wide subscription to an AI aggregator tool now available to all students, faculty, and staff (in part, from what I understand, as an attempt to effect some boundaries). And then, in the news, all this hand-wringing over the end of humanity, etc., on the one hand and techno-utopian promises on the other.

2026 18th Annual Student Center For Science Engagement Research Symposium, Student Center For Science Engagement

Student Center for Science Engagement Research Symposium

Student presentations in Biology, Chemistry, Physics, Earth Science, Environmental Science, Computer Science, Mathematics, & Psychology

The Zero-Point Game℠: A Signed-Balance Reciprocity Ledger With Annual Balance Reset, Non-Convertible Social And Environmental Accounts, And An Ai Coordinator For Routing And Magnitude, Thon Ly

Defensive Publications Series

We specify a signed-balance reciprocity ledger, played as an ongoing non-zero-sum game, in which each recorded kindness posts an equal-and-opposite pair: the giver's balance moves positive and the receiver's negative by the same magnitude, so the sum across participants is zero by construction, and a participant returns toward zero only by passing an imbalance onward. Balances are never a store of value or a claim on goods. Components: (1) a self-directed acknowledgment event whose forwarded half, under a fifty-fifty forwarding rule, is re-issued to another participant, starting circulation without a prior counterparty; (2) two segregated, non-convertible balances per participant, one …

Sustaining Small Tutorial, Coaching, And Shadow Education Operations In Nigeria, Adeyinka Adebose Dawodu

Walden Dissertations and Doctoral Studies

Some tutorial and training center managers lack effective strategies effective business sustainability strategies, resulting in poor performance and reduced profitability. Tutorial business stakeholders realize that failure of these centers creates a loss of opportunities for Nigerian youth who depend on their training and preparatory services. Grounded in the performance prism framework, the purpose of this qualitative multiple case study was to identify and explore effective strategies that Nigerian Tutorial/training center managers use to sustain their centers beyond 5 years. The participants were six managers of tutorial/training business centers who have sustained their centers in nonaffluent areas of Lagos and Ogun …

Factors Influencing Non-Perennial Stream Initiation In The Mt. Hood National Forest, Allison Bast

Dissertations and Theses

Historically, non-perennial headwater streams have been overlooked due to their small size and infrequent flow regimes, often leading to them not being recognized as legitimate streams, despite scientific evidence that has shown these streams significantly affect the quality of downstream waters. To combat this issue, environmental managers need to be able to accurately identify and delineate the origins of these streams; however, despite decades of research, an accurate, universal method for predicting how and where these streams commence has yet to be developed. Early studies conducted in steep, humid environments, identified a strong inverse linear relationship between the size of …

2026 Final Bpsou Backfill And Cover Material Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Reducing Drag Of Vehicles With Half-Stepped Cylinder Surfaces Part I: Numerical Optimization, Ryan Moffit, Hamid Rahai, Komal Gada

Mineta Transportation Institute

Aerodynamic drag is a major source of energy loss for vehicles, increasing fuel consumption, reducing the driving range of electric vehicles, and contributing to greenhouse gas emissions. For a vehicle, the major components of its drag are pressure and viscous drag. Engineers have developed a variety of strategies to reduce drag, including streamlined vehicle designs, surface modifications, and devices that alter airflow around the vehicle. This research focuses on reducing the viscous drag. Specifically, this study investigates whether microscopic surface features called half-stepped cylinder arrays can reduce skin friction by altering the turbulent boundary layer and promoting smoother airflow near …

Board Of Trustees Agenda, Sep. 25, 2026, Indiana State University Board Of Trustees

Board of Trustees

Indiana State University Board of Trustees meeting agenda

Pyrolysis Of Biomass Feedstocks For Hydrogen-Enriched Syngas Production: Cold Gas Efficiency Modelling, Latin Hypercube Uncertainty Analysis, And Parametric Stress Analysis, Hadi Taghavifar, Thomas Allison, Hao Chen, Dibyendu Roy, Abdullah Malik, Yaodong Wang, Anthony Paul Roskilly, K.V. Shivaprasad

School of Engineering, Computing and Mathematics

Biomass-derived syngas offers a viable pathway for producing renewable, hydrogen-rich fuel gas. However, its conversion performance is influenced by feedstock type, temperature, feed rate, and moisture content. This study develops a Cold Gas Efficiency (CGE) model for four agricultural feedstocks: wheat, barley, oilseed rape, and beans. Temperature-dependent regression correlations are developed for the main syngas components and gas flow rate using experimental data. Results show that CGE is highly sensitive to temperature, with low-temperature stress (0–5th percentile) reducing mean CGE by up to 22%. High-moisture stress (95–100th percentile) produced an even larger decline, lowering mean CGE from ∼44% to ∼35% …

Modeling Preannouncement And Launch Timing Decisions For Product Line Extension Under Innovation Uncertainty And Resource-Sharing Dual-Sourcing Supply Chain, Adewole Adegbola, Venkat Allada

Engineering Management and Systems Engineering Faculty Research & Creative Works

This research seeks to develop a system dynamics (SD) model to address challenges associated with the product line extension (PLE) problem. In this work, we specifically consider the "Two-Generation Product Line Extension (TGPLE) Problem", where a firm introduces a product variant in the market and plans to extend the launch to include a newer generation product in a resource-sharing dual-sourcing (RSDS) environment. We begin by identifying the key factors that influence product line extension, and we developed a TGPLE-RSDS construct based on three (3) inter-related systems: Market System, Production System and Supply Chain System. The proposed TGPLE-RSDS construct also illustrates …

Powers' Conjecture On The Third Largest Eigenvalue Of A Graph, Kevin Schmidt

Master's Theses

In 1989, David Powers conjectured that for any connected graph G on n vertices, the k-th largest eigenvalue of the adjacency matrix satisfies λk(G) ≤ ⌊n/k⌋ for every 1 ≤ k ≤ n/2. The conjecture has since been resolved case by case, in the sharper form λk(G) ≤ n/k − 1: the case k = 1 is classical, k = 2 was settled independently by Hong and by Powers in 1988, and k ≥ 4 was shown to fail by Nikiforov and Linz. This thesis surveys the resolution of the remaining case, k = 3, achieved in March 2026 by …

Imsa 2026 Profile, Office Of College And Academic Counseling

IMSA Profile

The nationally-ranked Illinois Mathematics and Science Academy (IMSA) develops creative, ethical leaders in science, technology, engineering and mathematics. As a teaching and learning laboratory created by the State of Illinois, IMSA enrolls academically talented Illinois students in its tuition-free residential Academy for grades 10-12. Students are challenged with a rigorous curriculum designed to develop them into problem solvers and critical thinkers. Notable IMSA students include YouTube Co-Founder Steve Chen, PayPal Co-Creator Yu Pan, Yelp Co-Founder Russell Simmons, SparkNotes and OkCupid Co-Founder Sam Yagan, and Hearsay Social Founder Clara Shih.

Therapeutic Outcomes Of Oral Antibiotics For The Treatment Of Methicillin-Resistant Staphylococcus Aureus Urinary Tract Infections: A Multisite, Retrospective Cohort Study Of Linezolid, Trimethoprim–Sulfamethoxazole And Doxycycline, Ryan Mccall, Elena Gatskevich, Steven E. Fiester, Michael Floren, Elisabeth Chandler

Chemistry Publications

Background: Methicillin-resistant Staphylococcus aureus (MRSA) urinary tract infections (UTIs), while relatively uncommon, pose a unique challenge in treatment as only specific intravenous (IV) options are typically utilized, with the efficacy of oral antimicrobials being poorly defined. Methods: The multi-site retrospective cohort study described herein therefore aims to characterize outcomes associated with oral administration of linezolid, trimethoprim-sulfamethoxazole (TMP-SMX), or doxycycline for the treatment of MRSA UTIs. Study participants were adults with culture-positive MRSA UTIs receiving one of the three oral therapies. Exclusion criteria included polymicrobial UTI, concomitant MRSA outside the urinary tract, receipt of non-study anti-MRSA agents for greater than or …

Access In Teaching Stem Subjects To The Blind, Ashley E. Neybert

Journal of Science Education for Students with Disabilities

There are still many gaps in the literature regarding the difficulties faced by instructors of students who are blind and low vision and who teach Science, Technology, Engineering, and Math (STEM) subjects. We surveyed 26 K-12 STEM teachers about accessible materials they are aware of versus which accessible materials they use in their classrooms, their thoughts on how common challenges identified in the extent literature affect them in their teaching, and their perspective on how much extra time may be required for blind and low vision students (if any) to effectively learn STEM subjects.

Transforming Military Spectrum Management With Spectrack, Rachel Mccoy, Rafa Gould, Abby Fornadel

James Madison Undergraduate Research Journal (JMURJ)

The U.S. military faces operational and financial challenges due to inefficient electromagnetic spectrum
management. This poster and accompanying research statement introduce our minimum viable product, SpecTrack, which we created in response to a challenge presented by the U.S. Department of Defense's Joint Spectrum Agency. SpecTrack centralizes and visualizes spectrum requests to offer insights, streamline communication, and reduce costs. It integrates with current tools like Spectrum XXI and HUNSWDO while enhancing usability through a visual Common Operating Picture (COP). Our user-centered design process included stakeholder interviews and site visits to Germany. The result: a scalable platform that modernizes and simplifies military …

System And Method For Asynchronous Network Simulation Telemetry, Topological Environment Remediation, And Generative State-Machine Security, N/A

Defensive Publications Series

An automated, state-aware network orchestration and evaluation platform provides asynchronous security exercise assessment and environment management. The platform initializes isolated virtual guest environments by executing guest agent software that dynamically generates unique boot-time cryptographic artifacts and sends them to a centralized evaluation engine to dynamically compile a grading rubric. User submissions are evaluated using a dual-pipeline generative language model configured with a strict schema contract that concurrently determines semantic equivalence and detects structural anomalies or prompt injection attempts. Trainee progression across simulation objectives is tracked using a topological directed acyclic graph that triggers automated hypervisor commands to mutate guest environment …

An Experimental-Verification Program For The Corpus Mechanisms Of The Register Of Anticipated Ai Failure Modes, Volodymyr Kotegov

Defensive Publications Series

Companion document to the Register of Anticipated AI Failure Modes.

Purpose: to turn each of the register's 12 domains from a general statement that "experimental verification is needed" into a concrete, honestly bounded plan — stating what is testable now, by what means, at what stage, and what is categorically not testable by a small group at present.

Program design: (1) each proposed experiment carries an explicit evidence-class label, separating results that can move a domain’s Mapping status from results that only confirm a mechanism’s internal logic in isolation; (2) Phase 0 is limited to the one item in this …