Digital Commons Network^™

Assessment Of The Influence Of Human Activities On The Occurrence Of Forest Fires In Thailand Via Multiple Linear Regression (Mlr), Sittipong Ruktamatakul, Jirarat Insuk, Benjaporn Pinwongpet, Sarisa Ruktametakul, Pornpis Yimprayoon

Applied Environmental Research

Forest fires represent one of the most critical environmental challenges in Thailand, with impacts varying depending on forest type, fuel characteristics, terrain conditions, fire intensity, and the frequency of fire occurrence on the same landscape. While forest fires can contribute to ecosystem degradation, biodiversity loss, and the depletion of natural resources, such effects are not uniformly severe across all forest ecosystems. Understanding the human-induced factors contributing to forest fire occurrence is crucial for developing effective prevention strategies and promoting sustainable forest management. This study aimed to identify the anthropogenic factors influencing forest fire areas in Thailand via multiple linear regression …

Effect Of Chromium Doping On The Uv- And Sunlight-Driven Photocatalytic Performance Of Srtio3, Ro’Ikhatul Jannah, Dianisa Khoirum Sandi, Fahru Nurosyid, Risa Suryana, Didier Fasquelle, Yofentina Iriani

Applied Environmental Research

Chromium (Cr)-doped strontium titanate (SrTiO3, STO) photocatalysts with compositions of SrTi1-xCrxO3 (x = 0, 5, and 10%) were prepared via the coprecipitation method. This study aimed to investigate the effects of Cr doping on structural, morphological, and optical properties. Furthermore, this work aimed to examine the photocatalytic performance of pure and Cr-doped STO against methylene blue (MB) degradation under ultraviolet (UV) and sunlight exposure. X-ray diffraction confirmed the formation of the cubic STO phase and the insertion of the Cr dopant in the STO structures. Furthermore, Cr doping reduced the lattice constant, crystallite size, and average particle size and narrowed …

Fabrication Of Acid-Modified Corn Plant By-Product-Based Biochar For Efficient Adsorption Of Sulfamethoxazole From Aqueous Solutions, Thi An Hang Nguyen, Thi Duyen Le, Thi Hang Bui

Applied Environmental Research

Antibiotic pollution is of great interest owing to growing concerns about antibiotic resistance worldwide. This study aims to fabricate acid-modified biochar (CBM-A) from corn plant byproducts (CRs) for sulfamethoxazole (SMX) adsorption in aqueous solutions. CBM-A was synthesized via pyrolysis at 700 °C and modified with 14% H3PO4. Kinetics, isotherms, and thermodynamics were investigated in combination with material characterization to elucidate the adsorption behaviors and mechanisms. The results showed that pyrolysis and acid modification effectively enhanced SMX adsorption by CR because of the increased number of binding groups, specific surface area, and porosity. SMX adsorption on CBM-A was optimized at a …

Blue Carbon Stock Assessment And Climate Resilience Potential Of Mangrove Forest In Hung Thang Commune, Vietnam, Hla Phong Ko, Pham Hong Tinh, Nguyen Thuy Duong

Applied Environmental Research

Mangrove forests are vital blue carbon sinks that contribute to climate change mitigation and coastal resilience. This study assessed the carbon stock and spatial‒temporal dynamics of a mangrove forest in Hung Thang commune, Hai Phong Province, Vietnam, via a combination of field measurements, soil organic carbon (SOC) analysis, and normalized difference vegetation index (NDVI)-based remote sensing models. The results revealed that mangroves in the Hung Thang community store an average of 87.42 tC ha-1, with SOC accounting for approximately 19% of the total carbon. A generalized additive model (GAM) analysis revealed a consistent increase in carbon stocks between 1996 and …

Fabrication Of Urea With Amorphous Silica To Increase Rice Growth In Saline Soils, Thi Ha Chi Nguyen, Thi Hang Thuc Ha, Minh Phuong Nguyen, Ngoc Chuc Pham, Quang Bac Nguyen, Nguyen Huy Tuan Do, Ngoc Nhiem Dao, Trung Kien Nguyen

Applied Environmental Research

In recent decades, the decrease in rice cultivation areas in Vietnam, particularly in the Mekong River Delta, caused by climate change and soil salinization, has posed serious challenges for sustainable development. In addition to irrigation and agronomic practices, fertilizers that sustain rice growth under saline conditions play a crucial role in improving crop productivity. Amorphous silica has been reported to increase plant tolerance to drought, salinity, and heavy metal stress. In this study, nanosilica-coated urea (UCS) fertilizers were synthesized by coating urea granules with 1–5 wt% amorphous silica. The products were characterized by SEM, XRD, FTIR, TG‒DSC, and EDX to …

Heavy Metals And Organic Carbon In Sediments Of Seagrass Sediments Of Trang Province, Thailand, Siriporn Pradit, Pornthep Wirachwong, Thongchai Nitiratsuwan, Sujaree Bureekul, Supraewpan Lohalaksanadech, Thawanrat Kobkeatthawin, Monticha Jirajaras, Prakrit Noppradit, Sanya Sirivithayapakorn

Applied Environmental Research

In this study, the accumulation of heavy metals (Cd, Cr, Cu, Fe, and Pb) in water, suspended sediments, sediments, and seagrass in Kalase Bay, Trang Province, Thailand, during the 2024 dry season was investigated. These findings indicate that the enrichment factor (EF) for all the metals was less than 1, suggesting that anthropogenic contamination is not a significant concern in the area. The translocation factor (TF) values were less than 1 for all the metals except Cu, whose TF was greater than 1; however, these values were not statistically significant, indicating limited phytoextraction capacity. The bioconcentration factor (BCF) values for …

Spatial Modeling Of Natural Disaster Risk By Integrating Hazard, Vulnerability, And Exposure Factors Using Geospatial Techniques : Evidence From Mueang Tak District, Thailand, Suphatphong Ruthamnong

Applied Environmental Research

This study presents a comprehensive multihazard risk assessment for Mueang Tak District, Thailand, that integrates hazard, vulnerability, and exposure (H-V-E) dimensions. By utilizing geographic information systems (GIS) and remote sensing, the analytic hierarchy process (AHP) was employed to prioritize critical risk factors. GIS analysis integrated multisource spatial data, including Landsat 9 and Sentinel-2 imagery, CHIRPS precipitation, and SRTM-derived topography, while AHP weights were established on the basis of expert judgment and socioeconomic indices such as the relative wealth index (RWI) and population statistics. The results delineate distinct spatial risk clusters: high landslide potential is concentrated in the steep terrain of …

Carbon Stock Assessment In Sonneratia Apetala Afforested Mangroves : A Case Study From Cox’S Bazar, Bangladesh, Mohammad Ismail, Sayed Abu Johany, Tanmoy Dey, Zakia Sultana Teasa, Trishna Das, Prabal Barua, Tonima Hossain, Sajib Ahmed

Applied Environmental Research

Sonneratia apetala is a key species for mangrove afforestation projects in Bangladesh and plays a crucial role in ecosystem restoration and carbon sequestration. The research on how the total carbon stock (TCS) varies across S. apetala plantations in Cox’s Bazar remains limited. Thus, in this study, the biomass and soil carbon stock were quantified across nine S. apetala afforested sites in Cox’s Bazar to assess spatial variation and influencing factors. The total biomass carbon (TBC) was calculated by summing the aboveground (AGBC) and belowground (BGBC) biomass carbon, while the soil organic carbon stock (SOCS) was determined from the 0–40 cm …

Seasonal Wastewater Monitoring And Quantitative Microbial Risk Assessment Of Escherichia Coli In A University Wastewater System, Pathum Thani, Central Thailand, Natsima Tokhun, Natagarn Tongphanpharn, Weerawat Ounsaneha, Montip Jankeaw, Wiriyabhorn Klomsungcharoen, Patsara Wongsudi, Yawanart Ngamnon, Cheerawit Rattanapan, Kwang Mo Yang

Applied Environmental Research

In this study, the physicochemical properties of wastewater were characterized, and a quantitative microbial risk assessment (QMRA) of E. coli was conducted in the wastewater treatment system of the Faculty of Science and Technology, Valaya Alongkorn Rajabhat University, under the Royal Patronage, Pathum Thani, Thailand (VRU-SciTech). This study was conducted because the current water-quality assessment does not include the QMRA or evaluate the occupa-tional and incidental public risk of infection. Over a one-year monitoring period, this study quantified wastewater generation (~6.09 L person-1 day-1; ~3.21 × 103 m3 year-1) and analyzed its physicochemical parameters and E. coli concentrations. High concentrations …

Performance And Mechanisms Of Activated Natural Coagulants For Efficient Microcystis Removal Via Coagulation–Flocculation In Thailand, Apiradee Sukmilin, Peangtawan Phonmat, Ratcha Chaichana

Applied Environmental Research

Thailand produces fruit peels and seeds rich in natural polymers, which can serve as eco-friendly coagulants to control algal blooms. In this study, banana peel (Musa spp.), orange peel (Citrus sinensis), basil seed (Ocimum basilicum) mucilage, and chia seed (Salvia hispanica) mucilage were used. These activated natural coagulants with aluminum were compared with nonactivated and commercial coagulants (ferric sulfate, ferrous sulfate, and polyaluminum chloride) for Microcystis removal. Phytochemical composition analysis, Fourier transform infrared (FTIR) spectroscopy, and oxidation–reduction potential (ORP) analysis were conducted. The results revealed that banana and orange peels contain phenolic compounds, …

Evaluation Of Soil Moisture Content, Ph, And Dominant Microorganisms In Crude Oil–Contaminated Soil Treated With Cow Dung, Indole-3-Acetic Acid (Iaa), And Simulated Microgravity, Amenze Ovenseri, Tawari-Fufeyin P.

Applied Environmental Research

Crude oil negatively affects soil physicochemical properties and microbial activity, thereby hindering plant growth and posing notable environmental and agricultural issues. The combined effects of cow dung, indole-3-acetic acid (IAA), and simulated microgravity on the recovery of soil degraded by crude oil were explored using Zea mays as the test plant. Soil was contaminated with crude oil at different concentrations (0%, 1%, 3%, and 5% v/w), with each concentration comprising eight treatments: cow dung, Zea mays seeds exposed to microgravity, and IAA alone or in combination. Changes in plant height, soil pH, soil moisture content, and soil microbial diversity were …

Evaluating Sediment Control Strategies Using Swat Based Bmp Assessment In A Tropical Highland Watershed, Northern Thailand, ฺBanchongsak Faksomboon, Wilailak Suanmali

Applied Environmental Research

Soil erosion remains a critical environmental challenge in the tropical highland watersheds of Southeast Asia, where steep terrain, intense monsoonal rainfall, and intensive land use interact to accelerate sediment generation and downstream degradation. This study aims to quantify spatial patterns of sediment yield and to systematically evaluate the effectiveness of individual and combined best management practices (BMPs) at both the watershed and subwatershed (SWW) scales using the Soil and Water Assessment Tool (SWAT) in a tropical highland watershed in northern Thailand. Baseline simulations reveal pronounced spatial heterogeneity in erosion severity, with substantial portions of the watershed exhibiting moderate to extreme …

Metal–Organic Frameworks : Opportunities And Challenges In Nutrient Recovery, Suchana Amnuaychaichana, Chi-Wang Li, Pongsak (Lek) Noophan, Sumeth Wongkiew

Applied Environmental Research

Nutrient recovery from waste streams is a critical strategy for promoting sustainable agriculture and mitigating environmental degradation. Essential nutrients commonly present in organic waste and wastewater, such as nitrogen and phosphorus, can be reclaimed and reintegrated into agricultural systems. Metal‒organic frameworks (MOFs), which are composed of metal clusters coordinated with organic ligands, have emerged as promising materials for adsorption and have the potential for nutrient recovery and pollutant removal because of their high porosity, large surface area, and tunable physicochemical properties. These attributes enable MOFs to serve in diverse applications, including heavy metal adsorption, organic pollutant degradation, and nutrient transformations. …

Exploring Consumers’ Intention And Behavior In The Circular Economy : Evidence From Vietnam, Tuan Hoang Nguyen, Vo Minh Thang Phan

Applied Environmental Research

This study aims to address the key gaps in understanding the factors influencing the intention–behavior relationship of consumers in the context of the circular economy (CE). Grounded in the theory of planned behavior (TPB), this research extends the framework by integrating social pressure, attitudes toward green consumption, and the availability of CE products as crucial components that shape intention and behavior. Data were collected from 603 Vietnamese consumers and analyzed using partial least squares structural equation modeling (PLS-SEM). The results confirm the core TPB constructs, with perceived behavioral control emerging as the most influential factor. Notably, attitude toward green consumption …

Sustainable Approach For The Removal Of Cu(Ii) From Aqueous Solutions Using Lotus Seedpod-Alginate Composite Biosorbents, Lan Tran-Nguyen, Hue Tran Nguyen-Le, Hong T Hi Anh Nguyen, Tran Nguyen-Phuong-Dung, Ly Kim-Phung, Huynh Quoc-Khanh, Nguyen Minh-Nhut, Phuong Lan Tran-Nguyen

Applied Environmental Research

Turning waste or agricultural byproducts into valuable products has recently become a concern of scientists. In this study, the facile and cost-effective synthesis of a biocomposite derived from lotus seedpod (LS) and alginate (AG) was further applied for Cu2+ ion uptake from aqueous solutions. SEM images revealed the layered structures of the composites, which were thin and irregularly stacked sheets of a complex 3D network. The abundant functional groups on the surface of the LS-based material and its negative zeta potential value of -37.50 mV also facilitated efficient Cu2+ removal. Adsorption results revealed a Cu2+ adsorption efficiency (AE) and experimental …

Tree Composition And Carbon Sequestration Potential Of A University Campus In Bangkok, Thailand, Chaiwat Boonpeng, Pawanrat Butrid Butrid, Marisa Pischom, Satatip Noikrad

Applied Environmental Research

Trees play important roles in atmospheric carbon dioxide (CO2) absorption and climate change mitigation. The objective of this study was to assess tree characteristics and carbon sequestration potential at Ramkhamhaeng University (Hua Mak Campus), Bangkok, Thailand. Tree attributes, including species composition, abundance, diameter at breast height (DBH), and tree height, were recorded. Tree biomass, carbon storage, and CO2 sequestration were estimated using appropriate allometric equations. A total of 2,149 trees were recorded in the study area, corresponding to a tree density of 45.8 trees ha-1. The tree community was dominated by the palm family (Arecaceae), while Terminalia ivorensis was the …

Development Of A Deep Neural Network Model To Predict Pm2.5 Concentrations Based On Key Factors Affecting Air Pollution In Bangkok, Natsuda Klinklan, Tanawut Poothong, Nuttiwut Areeratphitak, Viganda Varabuntoonvit

Applied Environmental Research

PM2.5 is a significant air pollution concern in Thailand, particularly in urban areas such as Bangkok, where the 24-hour average concentration frequently exceeds national ambient air quality standards during severe seasonal episodes. Road transportation is the primary source of PM2.5 in Bangkok, accounting for 73% of total emissions, according to the Pollution Control Department. In this study, a predictive modeling framework is developed to investigate the relationship between vehicle count and the mass concentration of PM2.5 from vehicular exhaust emissions. Convolutional neural networks (CNNs) and recurrent neural networks (RNNs) are employed for vehicle detection and counting, whereas a long short-term …

Weekly Spatiotemporal Dynamics Of Forest Fire Hotspots In Tak Province, Thailand : A Gis-Based Directional Analysis, Suphatphong Ruthamnong

Applied Environmental Research

Forest fires are recurrent dry-season hazards in northern and western Thailand, yet their short-term spatial dynamics remain insufficiently understood. In this study, weekly spatiotemporal dynamics of forest fire hotspots in Tak Province, Thailand, were examined using Visible Infrared Imaging Radiometer Suite (VIIRS) active-fire data and GIS-based directional analysis. Hotspots from five fire seasons (2021–2025) were grouped into 24 weekly intervals beginning on 1 December. The analysis integrated weekly hotspot counts, forest-type compositions, mean-center trajectories, standard deviational ellipses, temporal changes in topographic characteristics, and fishnet-based hotspot persistence mapping. The results revealed that fire activity was highly concentrated during the middle of …

Effects Of The Psb-To-Ow Ratio And Light Intensity On Biogas Composition During Phototrophic-Assisted Anaerobic Fermentation Of Organic Waste, Kridsana Jirasansawat, Sirilak Prasertkulsak, Nitiwist Teangthai

Applied Environmental Research

The integration of phototrophic processes into anaerobic fermentation offers a promising strategy for improving biogas quality; however, the combined effects of the photosynthetic bacteria-to-organic waste (PSB-to-OW) ratio and light intensity remain unclear. In this study, the photosynthetic bacteria (PSB)-assisted anaerobic fermentation of municipal organic waste under varying PSB-to-OW ratios and light intensities was evaluated. An optimal PSB-to-OW ratio of 1:2 resulted in significantly higher CH4 concentrations and lower CO2 and H2S concentrations than the other tested ratios did (p < 0.05). At this ratio, moderate illumination (2000 lx) resulted in the highest CH4 concentration (68.2 ± 0.3%), compared with 1000 lx (61.5 ± 0.4%) and 4000 lx (63.1 ± 0.5%). Under illumination, the CO2 and H2S concentrations were lower than those under dark conditions, indicating a more favorable biogas composition. Kinetic analysis indicated that CO2 and H2S exhibited apparent first-order behavior under illumination, with the highest rates occurring at 2000 lx (kH2S = 0.093 day-1; kCO2 = 0.059 day-1), suggesting light-dependent transformation processes. Metagenomic analysis revealed a microbial community dominated by sulfide-oxidizing (Chlorobium sp.), photoheterotrophic (Rhodopseudomonas sp.), and syntrophic bacteria, supporting coupled carbon conversion and sulfur transformation. Overall, optimization of the …

The Best Of Both Worlds: How Artificial Intelligence Can Balance Precision And Flexibility In Article 9 Search Logic, Lindsay Martin Mayes

Oklahoma Law Review

No abstract provided.

Modern Research Tools Supporting Science At Andrews University, Peter Lyons, Henry Navarro

Faculty Publications

No abstract provided.

Playworld Translanguaging: A Place-Based Approach For Translanguaging Play Pedagogy In Early Childhood, Christine Robinson, Carly Steele, Toni Dobinson, Grace Oakley, Samina Manado, Katie Grace, Graeme Gower

Research outputs 2022 to 2026

Conceptualised from a vision to honour children’s languages, agency and cultural ways of knowing, this research presents findings from a place-based translanguaging play pedagogy for early childhood called Playworld Translanguaging. In the remote Kimberley of Western Australia, researchers collaborated with educators in a Kindergarten/Primary/Yr 1 class of mostly Aboriginal children who have Bardi Jawi as their ancestral language, co-designing ways to revitalise this language through play pedagogy in ways intimately connected to place. Our Playworld Translanguaging approach reimagined Conceptual PlayWorlds (Fleer, 2018) with the intention of integrating pedagogical translanguaging. Following Indigenist research principles, critical participatory action research (CPAR) was the …

Synthesis And Characterization Of The New G3 Family Of Organoantimony(V) Cyanoximates, Thao Trang Phan

Graduate Theses/Dissertations

Bacterial infections pose a serious threat to humans by developing resistance, rendering antibiotics ineffective. Of the 12 antibiotics recently approved since 2017, 10 belong to an already existing class. Various resistance mechanisms, such as reduced drug uptake, active efflux, drug inactivation, and target modification, can significantly reduce the efficacy of entire classes of antibiotics. Discovering novel strategies to overcome diverse mechanisms of resistance and improve therapeutic efficacy is in high demand. Inorganic compounds with organic ligands (both complexes and organometallics) represent a new class of compounds against which antimicrobial resistance has not yet been established. Recently, we discovered two series …

Cost-Effective Design Of Home Energy Management System With Pv-Wind And Battery Storage In A Grid-Tied Microgrid, Md Mamun Ur Rashid, Jiefeng Hu, Md Alamgir Hossain, Md Shafiul Alam, Ismot Tasmary Salsabil, Bo Long

Research outputs 2022 to 2026

The rising energy demand and the limited availability of traditional energy sources have driven the search for renewable energy alternatives. Over the past few years, more renewable energy sources and significant efforts have been carried out around the World to decrease carbon emissions in the utility sector. To support this development, microgrids have emerged as a smart component of the future power grid. Microgrids, powered by local energy resources, are the most effective for building the new power grid. In microgrids, an Energy Management System (EMS) is an essential element in scheduling the local energy flows. This paper focuses on …

Psag: Projection-Based Stabilized Attribution Guidance For Online Continual Learning, Hang Yu, Kun Hu, Zhuqiang Lu, Steven Qiang Lu, Zhiyong Wang, Fengxiang He

Research outputs 2022 to 2026

Online Continual Learning (OCL) aims to incrementally learn from non-stationary data streams in a one-pass setting, facing the dual challenges of catastrophic forgetting and insufficient training. These challenges intensify the stability-plasticity dilemma, where pre-serving old knowledge conflicts with acquiring new information. In this paper, we propose Projection-based Stabilized Attribution Guidance (PSAG), a modular framework that leverages gradient-based attributions as active guidance signals to selectively preserve task-relevant representations. Our framework consists of three complementary mechanisms: (1) Attribution-Guided Feature Modulation (AGFM) that anchors critical features in the representation space; (2) Importance-Aware Loss Reweighting (IALR) that prioritizes informative samples at the loss level; …

Performance Of Chatgpt-4, Gemini, And Deepseek-V3 On English-Translated Questions From The Taiwan National Dental Technician Licensing Examination Over A Three-Week Period, Yi-Pang Lee, Ching-Yi Huang, Andy Sun, Chun-Pin Chiang

Journal of Dental Sciences

Background/purpose: Large language models (LLMs) have shown potential in answering professional examination questions. This study evaluated the performance of ChatGPT-4, Gemini, and DeepSeek-V3 in answering English-translated questions from the 2023 Taiwan National Dental Technician Licensing Examination (TNDTLE) over a three-week period.

Materials and methods: A total of 194 English-translated, text-based multiple-choice questions were selected from the 2023 TNDTLE. ChatGPT-4, Gemini, and DeepSeek-V3 were used to answer the same set of English-translated questions at four time points: baseline and one-, two-, and three-week follow-ups. Accuracy rates (ARs) were calculated and compared to evaluate changes over time and differences among the three …

Performance Of Chatgpt-4, Gemini, And Deepseek-V3 In Answering The Prompt-Engineered Questions From The Taiwan National Dental Technician Licensing Examination Over A Three-Week Period, Yi-Pang Lee, Ching-Yi Huang, Andy Sun, Chun-Pin Chiang

Journal of Dental Sciences

Background/purpose: Large language models (LLMs) have shown promise in answering professional examination questions. This study evaluated the performance of ChatGPT-4, Gemini, and DeepSeek-V3 in answering prompt-engineered questions selected from the 2023 Taiwan National Dental Technician Licensing Examination (TNDTLE) over a three-week period.

Materials and methods: A total of 194 Chinese-language text-based multiple-choice questions were selected from the 2023 TNDTLE. The three LLMs answered these questions using a standardized prompt referring to 17 dental technology textbooks. Accuracy rates (ARs) were recorded at baseline and after one, two, and three weeks. Comparisons of ARs over time, among three LLMs, between basic and …

Ensemble Learning For Predicting Periapical Lesions From Dental Radiographs, Fang-Yuan Liao, Ming-Jyun Jian, Abdullah Sarini, Yulianto Jesica, Yen-Kun Lin, Hsun-Yu Huang

Journal of Dental Sciences

Background/purpose: Diagnosing periapical cysts and granulomas using periapical radiographs is challenging due to subtle radiographic differences. This study aimed to develop a machine learning–based diagnostic framework to improve lesion classification through ensemble learning and dentin standardization.

Materials and methods: Five models—Support Vector Classifier (SVC), Nu-SVC, K-Nearest Neighbors (KNN) and Decision Tree—were trained on 144 pre-treatment periapical radiographs (70 cysts and 74 granulomas). Dentin standardization normalized grayscale values to ensure feature consistency. A weighted soft voting strategy was employed to integrate predictions, with model weights derived from individual diagnostic performance. Model performance was evaluated via five-fold cross-validation. Statistical significance among models …

Rigorous Validation Of Machine Learning Models For Orthodontic Extraction Prediction Using Nested Cross-Validation And Smotenc-Integrated Pipelines., Anh Thi-Ngoc Do, Hung Trong Hoang, Thuy-Trang Thi Ho, Hieu Ngoc Le

Journal of Dental Sciences

Background/purpose: Machine learning (ML) in orthodontics often suffers from optimistic bias due to data leakage and improper handling of class imbalance. This study implemented and evaluated a production-grade validation framework - nested cross-validation (CV) - for three distinct algorithm classes (logistic regression, random forest, and gradient boosting) using a consensus-labeled orthodontic dataset.

Materials and methods: A retrospective dataset of 500 patients (334 non-extraction/166 extraction) was curated with 41 processed features. Two stratified split protocols (70/30 and 80/20) were evaluated to assess model robustness. To ensure methodological rigor, a 5-fold outer/3-fold inner nested cross-validation was implemented. Crucially, SMOTENC (synthetic minority over-sampling …

Development Of A Risk Scoring System For Predicting Post-Extraction Medication-Related Osteonecrosis Of Jaws: A Derivation And Validation Cohort Study, Ling-Ying Wei, Ching-Ming Chiu, Sang-Heng Kok, Hung-Ying Lin, Wei-Yih Chiu, Hao-Hong Chang, Shih-Jung Cheng, Jang-Jaer Lee

Journal of Dental Sciences

Background/purpose: Although risk factors for medication-related osteonecrosis of the jaw (MRONJ) are known, clinical assessment prior to dental extraction remains largely subjective. We aimed to develop and externally validate a simple clinical risk scoring system to predict post-extraction MRONJ in osteoporotic patients receiving antiresorptive therapy (ART) and support evidence-based clinical decision-making.

Materials and methods: This retrospective cohort study used a derivation cohort (N = 1,067 extractions, 2003‒2022) to develop a 5- to 16-point risk score system based on five predictors (age ≥ 75, ART duration ≥ 24 months, bisphosphonate use, drug interruption < 3 months, and extraction site). The model was validated in an independent cohort (N = 928 extractions, 2022–2024) using a pre-defined ≥12 cut-off. Performance metrics included the area under the curve (AUC), sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).

Results: MRONJ prevalence was lower in the validation …