Digital Commons Network^™

The Response Of Child Protection Services To Prenatal Substance Exposure, Cierra Hassel

Dissertations, Theses, and Projects

Prenatal Substance Exposure (PSE) is a growing public health concern that requires Child Protection Services (CPS) involvement. CPS is a government agency that investigates child safety to determine whether child removal is necessary. Due to the increase of substance use during pregnancy, often linked to the opioid epidemic, more mandated reporters are submitting reports for positive drug tests at birth, which are screened in as neglect by the mother. PSE has significant implications for developing fetuses, potentially causing both short- and long-term behavioral, medical, and developmental challenges.  

Pregnant women with substance use disorder may often neglect prenatal care, as they …

Beyond The Bug: How The Covid-19 Pandemic Exposed Longstanding Systemic Failures In The United States Workforce And Economy, Abbey M. Markley

Honors Theses

The purpose of this thesis is to investigate and discuss how longstanding systemic failures in the United States exacerbated the effects the COVID-19 pandemic had on the American economy, essential healthcare workers, and overall public trust in institutions. A review of the existing literature surrounding this topic and the subsequent results of various studies were used to compose this thesis. The United States has a painful lack of worker protections and tends to view members of its workforce as expendable, even in times such as pandemic when they are deemed essential. Healthcare workers in particular faced increasing threats to their …

Determining The Relatedness Of Simian Varicella Virus Strains Using Polymerase Chain Reactions And Delta Herpesvirus-Dervied Primers, Ellyn M. Waits

Honors Theses

This study examines genetic variation among strains of Simian Varicella Virus (SVV) using genomic analysis. The primary goal of this experiment was to observe potential genomic differences among the Liverpool vervet virus (LVV), the Tsukuba herpesvirus, and the Delta herpesvirus (DHV) strains using primer sets developed from the fully sequenced DHV strain. SVV strains were initially cultivated in Vero cell cultures to begin viral propagation. Viral proliferation in these cell cultures enables DNA isolation via standard purification methods. The extracted viral DNA is subjected to polymerase chain reaction (PCR) amplification targeting specific regions of open reading frames (ORFs) in the …

Antibiotic Resistance Patterns In Bacterial Isolates From Mississippi Gulf Coastal Environments, Lawler F. Horn

Honors Theses

Coastal environments host diverse microbial communities that play essential ecological roles but may also serve as reservoirs for antibiotic-resistant bacteria. This study investigated patterns of antibiotic resistance in microbial isolates collected from public beaches along the Mississippi Gulf Coast. A total of 143 bacterial isolates exhibited growth and were included in antibiotic susceptibility screening. High levels of antibiotic resistance were observed, with 137 of 143 isolates showing growth on vancomycin, 124 on amoxicillin, and 102 on erythromycin. Resistance to kanamycin (19/143 isolates) and tetracycline (33/143) was less common. Multidrug resistance was widespread, with 101 isolates (70.6%) resistant to three or …

Community Composition Of Antibiotic-Resistant Bacteria On The Mississippi Gulf Coast, Marisa Martin, Colin Jackson

Honors Theses

The Mississippi Gulf Coast is an important resource for transportation, economic development, and recreation. Given its economic and cultural importance, it is crucial to maintain clean and safe conditions along the coast for public health, but other than routine beach monitoring, few studies have examined microbial contamination of coastal waters in this region. This study aimed to determine the quantity, composition, and distribution of bacteria resistant to six different antibiotics (Vancomycin, Kanamycin, Tetracycline, Ciprofloxacin, Erythromycin, or Amoxicillin) in seawater at seven public beaches along the Mississippi Gulf Coast. No bacteria resistant to Ciprofloxacin were detected, and bacteria resistant to Kanamycin …

Learning Across Disciplines: A Team-Based Approach To Ce, Carissa Blumenshine, Heather Raeder

Nursing

No abstract provided.

Evaluating Referral Coordination And Scheduling In Primary Care: A Qualitative Study Of Workflow Gaps, Aprupa Alahari, Philycia Foote, S. Vincent Grasso

Rowan-Virtua Research Day

Background

Healthcare referral workflows remain fragmented despite widespread adoption of electronic health records. Primary care to specialty referrals frequently rely on fax, phone calls, manual scheduling, and disconnected communication systems, creating delays, incomplete referrals, and administrative burden.1,2 Prior literature has identified a lack of referral tracking, referral leakage, and lack of closed-loop communication as major barriers to coordinated care. Altogether, efforts are required to keep cases from falling into the “referral black hole” that plagues health systems.2-4

Hypothesis

We hypothesized that:

1. there is substantial patient burden

2. there is substantial operational fragmentation

3. current referral systems contain limited visibility or verification

Methods …

Not All That Scratches Is Infection: Sweet Syndrome Mimicking Cat Scratch Disease, Clara Keum, Neelesh R. Parikh

Rowan-Virtua Research Day

Sweet syndrome, or acute febrile neutrophilic dermatosis, is a rare inflammatory condition characterized by painful erythematous skin lesions, neutrophilic dermal infiltration on histopathology, and rapid response to corticosteroid therapy. Although classically associated with fever and leukocytosis, atypical presentations without systemic symptoms are increasingly recognized, often leading to diagnostic confusion.

The clinical presentation of Sweet syndrome frequently overlaps with infectious processes such as cellulitis, particularly when lesions involve the lower extremities. This overlap may result in misdiagnosis and delayed appropriate treatment. Distinguishing between infectious and inflammatory etiologies is critical, as management strategies differ significantly.

We present a case of Sweet syndrome …

An Unusual Cause Of Generalized Weakness: Cns Toxoplasmosis, Christopher Dellmyer, Danielle Kusmaul, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

No abstract provided.

Case Report: Necrotizing Pneumonia, Veroneka Mikhail Md

Rowan-Virtua Research Day

Necrotizing pneumonia is an uncommon but severe complication of community-acquired pneumonia (CAP), characterized by progressive parenchymal liquefaction, cavitation, and destruction of normal lung architecture, and associated with significant morbidity and mortality. Clinicaly, early presentations may be indistinguishable from uncomplicated pneumonia (pna), with fever, cough, pleuritic chest pain, and dyspnea, which can delay recognition in the emergency department. Differential diagnosis for these symptoms is broad and includes uncomplicated pneumonia, septic emboli, lung abscesses, and pleural effusion. However, patients effected with necrotizing pneumonia often exhibit more severe systemic toxicity, rapid progression of respiratory failure, and hemodynamic instability. In this case report, we …

Improving Pediatric Vaccination Rates In The United States, Maanasi Dudi

Rowan-Virtua Research Day

Pediatric vaccination has been one of the most effective public health strategies for preventing infectious diseases and reducing childhood morbidity and mortality. However, vaccination rates have dropped in recent years, due to increasing vaccine hesitancy, as well as interruptions in regular healthcare during the COVID-19 pandemic. This has been reflected in primary care settings, where pediatricians are seeing more parents refuse vaccinations.

This literature review examines current trends in pediatric vaccination rates, factors contributing to vaccine hesitancy, and interventions that have been used to improve vaccination uptake. A systematic search of peer-reviewed literature was conducted on PubMed to identify studies …

Unusual Etiology Of Cauda Equina Syndrome In An Aids Patient: A Case Report, Wesley Augustus Kim, Brandon Velazquez

Rowan-Virtua Research Day

Patients with advanced HIV/AIDS are at high risk for primary central nervous system (CNS) lymphoma due to impaired immune surveillance and HIV-driven B-cell proliferation. While intracranial lesions are well recognized, spinal involvement remains underrecognized due to the scarcity of well documented report cases in current literature. In this patient,we describe the case of a 35-year-old male with a new HIV diagnosis who experienced acute bilateral lower extremity weakness and urinary retention during hospitalization for fever, perianal abscess, and urinary tract infection. Initial CD4 count revealed profound immunosuppression with a CD4 count less than 20 cells/μL and a viral load of …

Acute Necrotizing Pancreatitis Due To Hypertriglyceridemia: A Case Report, Samantha Alyse Walkow, Pranaya Gade, Marina Bastawross, Ayesha Ain, Antonios Tsompanidis

Rowan-Virtua Research Day

Title: Acute Necrotizing Pancreatitis due to Hypertriglyceridemia: A Case Report

Background: Necrotizing pancreatitis is a severe complication of acute pancreatitis with a high risk of morbidity and mortality. Hypertriglyceridemia (HTG) is an uncommon but increasingly recognized etiology, often associated with more severe disease compared to biliary or alcoholic pancreatitis. Early recognition and targeted management are critical to prevent multiorgan failure.

Case Presentation: We present the case of a 39-year-old Hispanic male with a history of chronic hypertriglyceridemia and epilepsy who presented with acute onset of severe epigastric pain, nausea, and vomiting. Laboratory evaluation revealed markedly elevated serum triglycerides (TG) levels …

Optimization Of Refolding, Purification, And Analytical Characterization Of Proinsulin(F25d) Soluble Antigen Array Immunotherapy, Abigail Richardson

McKelvey School of Engineering Graduate Student Theses & Dissertations

Type 1 Diabetes (T1D) is characterized by autoreactive immune responses to insulin and its precursor, proinsulin. Soluble antigen arrays (SAgAs) displaying the metabolically inactive proinsulin variant, proinsulin(F25D), represent a promising antigen‑specific immunotherapy candidate for T1D. However, the production of these platforms is hindered by substantial practical challenges, including protein aggregation, inefficient refolding, and the lack of sensitive analytical tools to verify quality and dosage. This work establishes an integrated, scalable pipeline for the purification, conjugation, and quantification of a proinsulin(F25D) SAgA. First, we optimized the refolding of recombinant methionine-proinsulin(F25D) (M-PI(F25D)) from inclusion bodies using controlled buffer systems and created a …

Case Report: Adult Distal Lleal Perforation Mimicking Meckel's Diverticulum, Dip Patel, Wayne Tamaska, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

Meckel’s diverticulum is the most common congenital anomaly of the gastrointestinal tract, but clinically significant disease in adulthood is uncommon and often difficult to diagnose before surgery. In adults, symptomatic Meckel’s most often presents with obstruction, bleeding, or inflammation, and cross-sectional imaging may not clearly distinguish it from other distal ileal processes.

We report the case of a 35-year-old man who presented with several days of fever, abdominal pain, vomiting, and diarrhea. CT imaging suggested a complicated distal ileal diverticular process, most concerning for perforated Meckel’s diverticulum with an adjacent abscess. He underwent emergent small bowel resection and abscess drainage. …

Case Report: Acute Encephalopathy Revealing Severe Babesiosis With Lyme Co-Infection, Czarina Gebrelle K. Soriano, James Espinosa, Alan Lucer

Rowan-Virtua Research Day

Acute confusion in older adults is a common emergency department presentation with a broad differential diagnosis. Tick-borne illnesses can cause significant systemic disease and may present with nonspecific neurologic or constitutional symptoms, making early recognition challenging. Babesiosis is a tick-borne parasitic infection transmitted by Ixodes ticks and may occur concurrently with other infections such as Lyme disease, further complicating diagnosis. We present a case of a 67-year-old male who presented with acute confusion and was found to have concurrent babesiosis and Lyme disease. This case highlights the importance of maintaining a high index of suspicion for tick-borne co-infections in patients …

When Venom Isn’T The Only Threat: Roseomonas Mucosa Bacteremia Following A Snake Bite, Cyrus Davati, Kishan Patel, James A. Espinosa Md, Alan Lucerna

Rowan-Virtua Research Day

Snake bites in the ED  overall are rare in the United States. While mortality is low due to modern interventions, the sequelae - including tissue necrosis, digit amputation, and subsequent infection  remain a significant concern.  Here we present the case of a  presumptively non-venomous snakebite, which  was associated with R. mucosa bacteremia.

A Pain In The Neck: Lemierre Syndrome Presenting With Retropharyngeal Abscess, Clara Keum, Leo Midure

Rowan-Virtua Research Day

Lemierre syndrome is a rare but potentially life-threatening condition characterized by septic thrombophlebitis of the internal jugular vein following an oropharyngeal infection. It is most commonly associated with Fusobacterium necrophorum,  and typically begins with pharyngitis or deep neck space infections, which can extend into adjacent vascular structures. Retropharyngeal abscesses are among the deep neck infections that may predispose patients to this complication due to their proximity to the internal jugular vein and surrounding fascial planes.

Although Lemierre syndrome classically occurs in otherwise healthy adolescents and young adults, it can also develop in immunocompromised individuals or patients with complex medical conditions. …

Case Report: Vancomycin-Resistant Enterococcus Faecium Urinary Tract Infection With Stercoral Colitis Presenting In An Elderly Patient, Muhammad Zain Raza, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

We report a case of a 76-year-old female who presented with altered mental status characterized by confusion, decreased verbal interaction, and reduced responsiveness noted by her spouse. The patient had a history of chronic constipation and was brought from home for further evaluation. Initial evaluation raised concern for infection or intracranial hemorrhage as a possible cause of altered mental status. Imaging of the CT brain without contrast was unremarkable, however; abdomen and pelvis revealed a large rectal stool impaction with rectal wall thickening and surrounding perirectal fat stranding consistent with Stercoral Colitis. Urine culture subsequently identified vancomycin-resistant enterococcus faecium. The …

A Rare Intervention: Emergency Ultrasound-Guided Pericardiocentesis Using A Central Line Kit, Alec Mirchandani, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

Cardiac tamponade is a life-threatening emergency requiring rapid diagnosis and drainage.

Point-of-care ultrasound (POCUS) expedites recognition and guides pericardiocentesis. We report a case of acute large pericardial effusion with hemodynamic collapse in a previously healthy 46-year-old female, managed emergently with ultrasound-guided pericardiocentesis using a central line introducer and subsequent pigtail catheter exchange; the clinical course was complicated by presumed septic pulmonary emboli and death.

Bacteriophage Therapy Vs. Standard Antibiotics: A Review Of Treatment Efficacy For Recurrent Pediatric S. Pyogenes (Gas) Infections, Kartik Kannan Oms-I, Karina Malhotra Oms-I, Gabrielle Coccio Oms-I, Janhavi Belwalkar Oms-I, Jason Rienzo Oms-I, Samay Shukla Oms-I, Valerie J. Carabetta Phd

Rowan-Virtua Research Day

Background: Antibiotic resistance poses a growing threat to pediatric infectious disease management, particularly in the treatment of Streptococcus pyogenes (GAS) infections.¹ While β-lactam antibiotics remain the first-line standard of care, their utility is limited by allergy prevalence and rising resistance among alternative antibiotic agents, such as macrolides, lincosamides, and tetracycline.^2,3 Given these trends, bacteriophage therapy has emerged as a promising adjunctive treatment modality, offering targeted bacterial lysis while sparing commensal microbiota.⁴

Methods: A systematic literature search was conducted across PubMed and Embase (2000–2025) using terms related to antibiotic resistance, Streptococcus pyogenes, bacteriophage therapy, and pediatric populations. …

Comparing Community-Based And Social Media Interventions To Improve Vaccine Uptake In Low-Income U.S. Populations, Tanisha Shah, Nico Santorelli, Maureen Kennedy, Aastha Lele, Syed Ahmad Bilal, Megan Chien, Judith Anne Lightfoot

Rowan-Virtua Research Day

Background:

In recent years, vaccination has become a highly politicized topic, contributing to decreased trust in medical professionals. Exposure to medical misinformation, distrust in government and research, and concerns about vaccine safety have all led to increased vaccine hesitancy and decreased vaccine uptake. These trends are more widely seen in low socioeconomic status (SES) and certain racial populations, posing a significant public health concern despite the effectiveness of vaccines.

Objective: This literature review aims to compare the effectiveness of community-based interventions led by clinicians and community health leaders with social media campaigns in increasing vaccine uptake among low-income populations in …

Defining Success In Collegiate Recovery Programs: A Systematic Review, Brooke Trogdon, John B. Moore

The Corinthian

Background: The transition to higher education is a critical period for emerging adults. Often marked by increased substance use experimentation due to a variety of internal and external factors. This group faces a heightened risk of developing substance-related health issues, necessitating targeted intervention and prevention efforts. Purpose: To systematically review and define key indicators of success for collegiate recovery programs (CRPs) that support students in recovery from substance use disorders (SUDs). Methods: Following PRISMA guidelines, a comprehensive search was conducted using GALILEO and Google Scholar databases. Articles were appraised using the JBI critical appraisal tools. Results: CRPs provide a supportive …

Exploring Child Trafficking Survivors' Experiences: Support, Revictimization, And Justice Institutions, Max Lubin

Walden Dissertations and Doctoral Studies

No abstract provided.

How The U.S. Virgin Islands Government Responded To The Covid-19 Crisis: A Leadership Perspective, Erica Dover

Walden Dissertations and Doctoral Studies

No abstract provided.

+Cd49a+Cd103+ Cytotoxic Tissue-Resident Natural Killer Cells Infiltrate And Control Solid Epithelial Tumor Growth In Mice, Nina B Horowitz, Jennifer A Foltz, Et Al.

2020-Current year OA Pubs

Human tissue-resident natural killer (NK) cells (trNK cells), broadly defined by markers of tissue residency, such as CD49a [

Cross-Sectoral Collaborations And Funding And Coordination Mechanisms In One Health Zoonoses Management In Peru, Lisset Dumet Poma, Erin S. Kenzie, Julia Goodman, Veronika Merino, Vanessa Cruz, Ruth Atto, Percy Vilchez, Seth O’Neal

OHSU-PSU School of Public Health Faculty Publications and Presentations

One Health (OH) is a comprehensive approach that recognizes the human-animal-environment interconnection to health and is applied to prevent and control zoonoses—diseases transmitted between animals and people. Using a multiple-method case study, we examined zoonoses networks, resource management mechanisms, and coordination strategies among policymakers and decision-makers of Peru’s human, agricultural, and environmental systems at national and sub-national levels. Social network analysis revealed collaborations between the human and agricultural systems, with limited connection with environmental systems. Only a few links were reported between national and sub-national government levels. Qualitative analysis identified structural barriers, including insufficient regulatory mechanisms for funding cross-sectoral activities. …

Genai Agent For Automated Analysis And Personalization Of Drug Prevention Campaigns, Mohammed Aljaafari, Shaymaa E. Sorour

Scientific Journal of King Faisal University: Humanities and Management Sciences

This study introduces a generative artificial intelligence (GenAI) agent designed to autonomously evaluate, optimize, and personalize drug prevention campaigns across Facebook, Reddit, Instagram, and Twitter (X) using a 45,000-post multi-platform awareness corpus. Five state-of-the-art large language models, GPT-5-mini, Claude 3.5, Gemini 2.0, Qwen 2.5, and Mixtral, were examined under six structured prompting families, including Original, Role-based, Two-Stage Explicit Sensemaking, and Case-Based Adaptive Reasoning in short and long variants. Model outputs were assessed using a tri-metric framework comprising the Educational Rate (Edu-R), Violation Rate (Vio-R), and Misleading Awareness Score (MAS), supported by classical discrimination and agreement measures, including ROC-AUC and Cohen's …

The Saudi Opinion On The Media Dealings With The Covid-19 Pandemic, Lotfi Ziadi

Scientific Journal of King Faisal University: Humanities and Management Sciences

Our research sought to monitor, measure and analyze the opinions and positions of Saudi men and women regarding the use of traditional and electronic media and social networking sites during the COVID-19 pandemic. We surveyed 477 Saudi men and women via an electronic questionnaire. The results show that Saudi respondents have increased their exposure to traditional media and that their use of social media has been intensified due to the pandemic. It was found that Saudis use social media to search for news and information that would help them understand the nature of the pandemic, how it spread, and what …

Social Media And Covid-19 Rumors, Saly Saad Goudah Ibraheim

Scientific Journal of King Faisal University: Humanities and Management Sciences

This study is intended to identify the public's attitudes towards spreading misinformation about COVID-19 through social media sites in the Jizan region in the Kingdom of Saudi Arabia. Being a descriptive study, it depends on the survey approach. The field study was conducted using an intentional sample of those who follow the developments of the COVID pandemic through social networking websites. 300 users completed an online survey. The study found high public awareness of the meaning of umor,' its effects, the reasons for its proliferation, and the potential motives of its promoters. Study recommendations include the importance of confronting rumors …