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2021g_Nhp74_Approved_Nc_Pt-7311-Therapeutic-Exercise-Ii-1, Graduate Council
2021g_Nhp74_Approved_Nc_Pt-7311-Therapeutic-Exercise-Ii-1, Graduate Council
All Approved Curriculum
No abstract provided.
Sociolooking: A Theory Of Looking Together And Choreographing Looking Experiences, Avigail Shimshoni
Sociolooking: A Theory Of Looking Together And Choreographing Looking Experiences, Avigail Shimshoni
Educational Studies Dissertations
Abstract
This dissertation addresses gaps in understandings of looking in research and practice by creating and defining sociolooking. Sociolooking is a theory of looking together and choreographing looking experiences. Researchers, educators, and practitioners across many fields value close looking and have offered step-by-step strategies for facilitating looking. While these strategies and related research are instrumental in understanding discrete aspects of looking and learning to look, they do not fully acknowledge or explore the underlying social and dynamic ways people engage in looking in everyday situations. This leads to the creation of one-dimensional, potentially inaccessible, or ineffective experiences. On the …
Progress And Challenges In Profiling Protein-Rna And Protein-Associated Rna-Rna Interactions, Zhuoyi Song, Eric L Van Nostrand
Progress And Challenges In Profiling Protein-Rna And Protein-Associated Rna-Rna Interactions, Zhuoyi Song, Eric L Van Nostrand
Faculty, Staff and Students Publications
RNA binding proteins (RBPs) play essential roles in post-transcriptional gene regulation by interacting with a wide range of RNA targets. In addition to regulating RNA processing via individual RBP-RNA interactions, there is a growing appreciation of the regulatory impact of protein-associated RNA-RNA interactions that include both well-studied examples of small regulatory RNAs (e.g. microRNAs, snRNAs, snoRNAs, piRNAs) guiding ribonucleoprotein complexes to their targets as well as structured RNA elements defining the interaction landscape for an RBP. To elucidate the full scope of RBP-RNA interactions, CLIP ( crosslinking and immunoprecipitation)-based methods have emerged as powerful tools. Even with the wide application …
The Impact Of Emotional Factors On The Functioning Of Selected Muscles: Facial Muscles, Trapezius Muscle, Diaphragm And Therapy Suggestions For Physiotherapists. A Systematic Review, Kacper Chojowski, Wojciech Janik, Piotr Steuer, Maciej Tomik, Michał Kuszewski
The Impact Of Emotional Factors On The Functioning Of Selected Muscles: Facial Muscles, Trapezius Muscle, Diaphragm And Therapy Suggestions For Physiotherapists. A Systematic Review, Kacper Chojowski, Wojciech Janik, Piotr Steuer, Maciej Tomik, Michał Kuszewski
Baltic Journal of Health and Physical Activity
Background: Extensive research has identified muscles that are particularly susceptible to emotional stimuli, namely the facial muscles, trapezius, and diaphragm. These muscles can respond to emotional stimuli by affecting the viscoelastic properties of muscles, especially stiffness. This study attempts to identify suggestions in evidence-based physiotherapy (EBP) for treating muscles that are particularly susceptible to emotions. Materials and methods: In order to achieve the goals, studies available in PubMed, PEDro, and Elsevier and Springer databases were analyzed. In the critical literature review, the following word combinations were selected: "muscle psychological stress," "muscle tonus stress," "trapezius stress," "diaphragm stress," "facial muscles stress." …
Biol 225 - Laboratory Manual For Human Physiology, Corey Sullivan, Kristin Thurlby, Gwen Wright
Biol 225 - Laboratory Manual For Human Physiology, Corey Sullivan, Kristin Thurlby, Gwen Wright
Human Physiology
This laboratory manual for Human Physiology represents the Creative Commons licensed (CC-BY-NC 4.0) material created as an Open Educational Resource.
Winter 2026, Office Of University Marketing And Communication
Winter 2026, Office Of University Marketing And Communication
Bryant Magazine (1997-2019)(2024-present)
This issue invites us to reflect on some of the remarkable achievements of the past year and to look ahead with purpose and passion. At the heart of this issue is a theme woven throughout our culture: working together, collaboration, and partnership, best summarized as teamwork.
Weeping And Virtus In Early Imperial Roman Epic, Mary Somerville
Weeping And Virtus In Early Imperial Roman Epic, Mary Somerville
Bryn Mawr College Dissertations and Theses
Are men always feminized when they weep? It is well-known that Greek epic heroes like Odysseus weep without losing their claim to masculinity; does the same rule hold true for Roman epic heroes? In this dissertation I examine how men weep in Roman epic poetry of the early Roman empire as an aspect of the performance of masculinity. Specifically, I explore the multiple valences of male tears and related emotional expressions across three core texts: Vergil’s Aeneid, Lucan’s Bellum Civile, and Statius’ Thebaid. I seek to understand judgments of and explanations for men’s tears within my sources, …
Effects Of Dietary Perfluorobutane Sulfonate (Pfbs) On Adipose Tissue, Hannah Olofintuyi, Eric Gato
Effects Of Dietary Perfluorobutane Sulfonate (Pfbs) On Adipose Tissue, Hannah Olofintuyi, Eric Gato
Honors College Theses
Per- and polyfluoroalkyl substances (PFAS) are chemical substances used in a variety of industrial applications and consumer products. Perfluorobutane sulfonate (PFBS) is often used as a replacement for the more harmful (Perfluoroalkyl sulfonate) PFAS chemicals that have been around longer. It is believed that PFBS does not remain in the body as long as other PFAS compounds; however, there is a rising concern that it has the potential to cause damage to human health. This study focused on understanding how dietary PFBS exposure affects metabolism-related processes in adipose tissues in rats. To accomplish study objectives, Sprague Dawley rats were exposed …
A Computational Approach To Graduated Centrifuge Profiles For Partial Gravity Planetary Environments, Cabell W. Jones
A Computational Approach To Graduated Centrifuge Profiles For Partial Gravity Planetary Environments, Cabell W. Jones
Mechanical & Aerospace Engineering Faculty Publications
Missions such as NASA’s Artemis and SpaceX’s Starship aspire towards creating permanent settlements beyond Earth. In order to achieve this goal, it must be considered that the gravity present on planetary surfaces such as the Moon (0.165 g) and Mars (0.378 g) may be insufficient to support human physiology for long term habitation. On near-Earth missions, issues such as muscular atrophy, neuro-ocular changes, cardiopulmonary variations, and bone mineral density loss have been observed proportional to the duration spent in microgravity. Further studies have suggested that the severity of these conditions scales linearly with decreasing gravity, meaning that astronaut health can …
Excess Nitric Oxide Alters Cellular Ph To Restrict Salicylic Acid Movement And Systemic Immunity, Fan Xia, Huazhen Liu, Keshun Yu, Xinyu Yuan, Aardra Kachroo, Pradeep Kachroo
Excess Nitric Oxide Alters Cellular Ph To Restrict Salicylic Acid Movement And Systemic Immunity, Fan Xia, Huazhen Liu, Keshun Yu, Xinyu Yuan, Aardra Kachroo, Pradeep Kachroo
Plant Pathology Faculty Publications
Plants carrying a mutation in S-nitrosoglutathione reductase 1 (GSNOR1) accumulate high nitric oxide (NO) and exhibit impaired immunity characterized by reduced pathogen-responsive salicylic acid (SA) accumulation and failure to activate normal SA signaling. We show that this reduced SA responsiveness in gsnor1 plants arises from impaired vascular-associated movement of SA, thereby compromising systemic acquired resistance (SAR). Elevated NO perturbs cellular pH homeostasis, acidifying the apoplast and alkalinizing the cytosol, which likely interferes with phloem-associated SA movement and renders gsnor1 plants unresponsive to foliar SA. In contrast, SA supplied via root drench restores SA signaling and SAR in gsnor1, …
In Vivo Telemetry To Record Long-Term Cardiovascular Parameters, Temperature, And Activity In Spinal Cord Injury Rat Models, Sajeev Kaur, Anna M. Baur, Jillian A. Condrey, Dorottya P. Gal, Samir P. Patel, John C. Gensel
In Vivo Telemetry To Record Long-Term Cardiovascular Parameters, Temperature, And Activity In Spinal Cord Injury Rat Models, Sajeev Kaur, Anna M. Baur, Jillian A. Condrey, Dorottya P. Gal, Samir P. Patel, John C. Gensel
Spinal Cord and Brain Injury Research Center Faculty Publications
Higher-level spinal cord injury (SCI) above thoracic level 6 (T6) disrupts autonomic function and contributes to secondary complications, including fluctuations in blood pressure, heart rate, and temperature. In rats, the placement of telemetric implants in the descending aorta offers a robust methodology for assessing various cardiovascular parameters, such as systolic and diastolic pressure, mean arterial pressure, and heart rate. Core body temperature and animal activity can also be recorded following telemetric implant placement. A rat with a telemetric implant is kept on the receiver plate connected to a computer system for recording various parameters. Continuous long-term recordings at defined time …
Ultrasound-Derived Liver Composition And Metabolic Flexibility Under Exercise Stress, Rhodes Van Houten
Ultrasound-Derived Liver Composition And Metabolic Flexibility Under Exercise Stress, Rhodes Van Houten
All Master's Theses
Metabolic Associated Fatty Liver Disease (MAFLD) is characterized by abnormal liver fat accumulation in conjunction with metabolic syndromes. MAFLD affects 33% of individuals worldwide, though little is known about how increased liver fat impacts physiological responses to exercise. This study aimed to analyze the relationship between liver composition and metabolic flexibility during a graded exercise test. Body composition was analyzed via dual-energy X-ray absorptiometry. Liver ultrasound was evaluated for echogenicity, where elevated mean gray volume (MGV) indicates abnormal liver tissue. Rates of fat (FATox) and carbohydrate (CHOox) oxidation (g/min), respiratory exchange ratio (RER), and blood lactate concentrations ([LA-], …
The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza
The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza
Honors Undergraduate Theses
Obesity has become one of the largest global health concerns of the 21st century, correlating with numerous associated diseases. To help address the growing prevalence and burden of obesity, sleeve gastrectomy and Roux-en-Y gastric bypass have become two commonly performed surgical procedures done to promote weight loss by altering the anatomical structure of the stomach and surrounding organs of the gastrointestinal system. Although the benefits of improved metabolism linked to these surgical procedures are well studied, their impact on the physiology of gastric cells, and more specifically chief cells as they relate to protein digestion post-surgery, is yet to …
How Effective Is Online Teaching Of Physiology Modules? Perception Of Rwandan Health Sciences Students, Abdullateef Isiaka Alagbonsi, Mojeed Akorede Gbadamosi, Mathieu Nemerimana, Makinde V. Olubiyi, Olufunke Onaadepo, Akaninyene Ubong Ime, Abdul-Rahuf Aderemi Feyitimi, Ruth Wanjiru Mungai, Florent Rutagarama, Simiat Elias
How Effective Is Online Teaching Of Physiology Modules? Perception Of Rwandan Health Sciences Students, Abdullateef Isiaka Alagbonsi, Mojeed Akorede Gbadamosi, Mathieu Nemerimana, Makinde V. Olubiyi, Olufunke Onaadepo, Akaninyene Ubong Ime, Abdul-Rahuf Aderemi Feyitimi, Ruth Wanjiru Mungai, Florent Rutagarama, Simiat Elias
Biomedical Sciences, East Africa
Background: While blended teaching is approved in Rwandan medical education, the perceived effectiveness of online-only delivery for physiology modules remains unclear. This uncertainty limits its continued use. The present study assessed Rwandan health sciences students’ perceptions of the effectiveness of online teaching for physiology modules.
Methods: A total of 528 students from medicine and surgery (n = 300), pharmacy (n = 99), dentistry (n = 89), and clinical psychology (n = 40) programs at the University of Rwanda completed an online questionnaire. Data were analyzed using multivariable logistic regression and non-parametric tests (Mann-Whitney U, Kruskal-Wallis) with corresponding effect …
Music To Move You: Comparing Effects Of Music Genre On Subjective Performance Of Football Players In A Practice Setting, Devin Deturk
Music To Move You: Comparing Effects Of Music Genre On Subjective Performance Of Football Players In A Practice Setting, Devin Deturk
PCOM Psychology Dissertations
Optimizing athletic performance has increasingly extended beyond conditioning to include psychological, health-related, and environmental interventions aimed at enhancing peak mental and physical fitness. However, advanced training mechanisms targeting these factors may not be readily available to all programs, necessitating cost-effective, accessible, and ethically sound adjuncts. Thus, music emerges as a potential solution that remains underutilized in applied sport settings but may be leveraged to address pervasive challenges such as fear of failure, burnout, and over-professionalization. The present dissertation investigated the effects of music in a practice setting, with particular emphasis on its capacity to enhance subjective performance, motivation, and positive …
Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous
Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous
Honors Undergraduate Theses
Cellular senescence is a biological process in which damaged cells exit the cell cycle while remaining metabolically active and accumulating within tissues. Senescence plays a complex role in breast cancer progression, largely through the secretion of senescence-associated secretory phenotype (SASP) factors. These factors include a broad range of inflammatory cytokines, chemokines, and signaling molecules that can influence the tumor microenvironment.
Studies suggest that senescence may significantly promote cancer metastasis. Therefore, this study aims to investigate the genes involved in cancer progression and to improve understanding of how SASP is regulated, which is critical for improving breast cancer outcomes. The central …
Enhancing Clinical Judgement In Pre-Licensure Nursing Students Through Active Learning Strategies Of Unfolding Case Studies And Simulations For Postpartum Hemorrhage, Lisa M. Alley
Doctor of Nursing Practice Projects
New graduate nurses lack the appropriate clinical judgement to provide optimal, safe, quality care, as evidenced by the report of errors in health care (Rodziewicz et al., 2024). The purpose of this project was to provide an evidence-based intervention that used an unfolding case study and simulation to further develop clinical judgement among undergraduate nursing students in a rural ADN program. The project used a pre-test and post-test to measure students' improvement prior to versus after the learning experience and debrief. This project also introduced a DASH tool, which is a debriefing assessment for simulations in healthcare, to help students …
Northeastern Illinois University, Academic Catalog 2026-2027, Northeastern Illinois University
Northeastern Illinois University, Academic Catalog 2026-2027, Northeastern Illinois University
Course Catalogs
No abstract provided.
Effect Of Plant-Based Vs. Standard American Diet On Cardiovascular Parameters In College Students, Timothy J. Horanic
Effect Of Plant-Based Vs. Standard American Diet On Cardiovascular Parameters In College Students, Timothy J. Horanic
Honors Undergraduate Theses
This study examines how adherence to different dietary patterns—specifically a plant-based diet compared to the standard American diet—can influence physiological indicators tied to cardiovascular health, including heart rate variability (HRV), blood pressure (BP), and heart rate (HR). Among these markers, HRV is considered especially sensitive to autonomic nervous system (ANS) regulation and may offer earlier insight into physiological stress or dysfunction than HR or BP alone. Although nutritional habits are widely believed to impact heart health, few investigations have focused on how specific long-term diets affect autonomic and cardiovascular metrics in healthy, college-aged adults. This study aims to investigate if …
Metabolic Mind: A Critical Literature Review On The Influence Of Mindset On Metabolic Health, Jordan Daniel M.A., M.S.
Metabolic Mind: A Critical Literature Review On The Influence Of Mindset On Metabolic Health, Jordan Daniel M.A., M.S.
Selected Full Text Dissertations, 2011-
Evidence has demonstrated that psychological processes can influence metabolic functions, which are essential to overall health, as impaired energy metabolism can compromise physiological systems (Bobba-Alves N et al., 2022). Metabolic health is defined as a state of well-being characterized by optimal levels of blood glucose, lipids, cholesterol, blood pressure, and adiposity and is the absence of metabolic dysfunction, which encompasses but is not limited to cardiovascular diseases, type 2 diabetes mellitus, obesity, and metabolic syndrome. A powerful psychological construct that has demonstrated its influence on health is a mindset. Defined as core beliefs or assumptions about oneself and the world, …
Pediatric Rheumatic Heart Disease Screening For Secondary Antibiotic Prophylaxis: An Explainable Shannon Energy Approach Using Heart Phonocardiogram In Northeast Brazil, Zhuohui Lin
Public Health Theses
Rheumatic Heart Disease (RHD), caused by Group A Streptococcus (GAS), remains a significant global health burden, particularly among children in low- and middle-income countries. Untreated GAS infection can lead to acute rheumatic fever and subsequent chronic valvular damage of RHD, such as mitral valve (MV) regurgitation. Hence, early detection is critical for the administration of Secondary Antibiotic Prophylaxis to prevent disease progression. Although deep learning models demonstrate high diagnostic accuracy, limited explainability restricts clinical adoption, especially in resource-limited settings. In this proof-of-concept study, we evaluated Shannon energy (SE) transformation as a proxy to differentiate holosystolic murmurs associated with RHD-related mitral …
24-H Circadian Rest-Activity Rhythms And Physical Frailty In Older Adults: A Biopsychosocial Perspective On Sex Differences And Social Capital, Jisu Kim
Theses and Dissertations
Physical frailty is a prevalent geriatric syndrome characterized by age-related decline across multiple physiological systems. Physical frailty is associated with an elevated risk of adverse health outcomes, including chronic disease progression and all-cause mortality, representing a significant and growing public health concern. Disrupted circadian rest-activity rhythms (RARs) are increasingly recognized as clinically meaningful markers of physical frailty in older adults. However, the extent to which biological sex and social determinants of health (SDoH), particularly social capital, contribute to or modify the associations between RARs and physical frailty remains underexplored.
Therefore, this dissertation summarizes the existing literature on age-related changes in …
Rest My Case: Sleep Science Should Inform J.D. Program Structures And Licensure Examinations To Enhance Performance, Equity And Well-Being, Laura J. Mott, Paula J. Manning
Rest My Case: Sleep Science Should Inform J.D. Program Structures And Licensure Examinations To Enhance Performance, Equity And Well-Being, Laura J. Mott, Paula J. Manning
Minnesota Journal of Law, Science & Technology
This Article critically examines the legal profession’s longstanding marginalization of sleep and circadian biology and argues that temporal structural norms embedded in legal education and licensure are at odds with established scientific evidence. Drawing on extensive and interdisciplinary research in neuroscience, chronobiology, cognitive psychology, and timekeeping, this Article explores how sleep deprivation and chronotype misalignment with institutional schedules impair attention, memory, emotional regulation, mental and physical health, and decision-making—capacities that are essential to competent, ethical, and sustainable legal practice. Despite robust scientific consensus that sleep quality, quantity, and timing have profound effects on performance and well-being, law schools and licensing …
Daily Rhythms In Psychosocial Stress, Sleep, And Mood: A Multimethod Approach To Transdiagnostic Psychopathology Risk And Intervention, Gabriel Gilmore
Daily Rhythms In Psychosocial Stress, Sleep, And Mood: A Multimethod Approach To Transdiagnostic Psychopathology Risk And Intervention, Gabriel Gilmore
Theses and Dissertations--Psychology
Rhythms are central to nearly every core physiological and psychological process and have profound influences on overall health and well-being, particularly in the context of mood disorders. This dissertation emphasizes a rhythm-centered framework for understanding transdiagnostic psychopathology, proposing that the temporal organization of psychosocial stress, sleep, and mood provides crucial information for the development and treatment of mood disorder symptomology. Current literature relies primarily on mean symptom levels, overlooking day-to-day patterns in psychosocial experiences. To address this key methodological gap, three studies are examined. Study 1 develops and validates the Psychosocial Stress Regularity Measure (PSRM), a brief single-item measure of …
Clinical Microbiology & Infectious Diseases: A Concise Guide On The Fundamentals Of Infectious Disease In Podiatric Medical Education, Paramita Basu
Clinical Microbiology & Infectious Diseases: A Concise Guide On The Fundamentals Of Infectious Disease In Podiatric Medical Education, Paramita Basu
Open Touro Created
2026
This Open Educational Resource (OER), Clinical Microbiology & Infectious Diseases, is a student-centered textbook designed to support pre-clinical podiatric medical students enrolled in PCLP 610 Infectious Diseases at the New York College of Podiatric Medicine. The book is structured as a collection of concise “chapter briefs” or high‑yield notes that align closely with the course syllabus, lecture objectives, and student learning outcomes, while also reflecting the Microbiology learning objectives outlined in the AACPM Council of Faculties Curricular Guide.
The content covers core principles of medical microbiology and infectious diseases, including bacteria, viruses, fungi, parasites, host–pathogen interactions, antimicrobial therapy, resistance …
Investigating The Effects Of Nucleopore Defects On The Cellular Response To Stress In Als/Ftd Ipsc-Derived Neurons, Alicia Christine Collins
Investigating The Effects Of Nucleopore Defects On The Cellular Response To Stress In Als/Ftd Ipsc-Derived Neurons, Alicia Christine Collins
Open Access Dissertations
Amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) is a progressive neurodegenerative disease spectrum characterized by motor dysfunction, cognitive decline, and death within a few years of clinical onset. Hallmark features of ALS/FTD include defects in nucleocytoplasmic transport (NCT) and abnormal cytoplasmic mislocalization and aggregation of the RNA-binding protein TDP-43, both of which have been shown to be exasperated by oxidative stress (OS). It remains unclear how these processes are connected and how they collectively contribute to neurodegeneration. To fill this gap of knowledge, we used human embryonic kidney cells, neuroblastoma cells, and induced pluripotent stem cell-derived cortical neurons harboring the ALS/FTD C9ORF72 …
Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan
Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan
Research outputs 2022 to 2026
This study manipulated the blood pH of participants to be mildly acidic or basic prior to passive hyperthermia to examine its effects on thermoregulatory and chemo-regulatory responses, including ventilatory parameters, rectal temperature (Tre) and thermal perception. Twelve healthy males attended three experimental sessions in a double-blind, randomised, counterbalanced design. Passive hyperthermia was induced by hot water immersion at 40°C following the consumption of corn starch (placebo; PLA), ammonium chloride (AC) or sodium bicarbonate (SB). Compared with PLA, SB consumption increased blood pH and HCO3−, whilst AC decreased both blood pH and HCO3− (all P < 0.001). Specifically, minute ventilation was unchanged following SB (11.0 ± 3.7 L min−1) but …
Bulletin Of Yale University School Of Nursing 2026-2027, Yale School Of Nursing
Bulletin Of Yale University School Of Nursing 2026-2027, Yale School Of Nursing
Yale School of Nursing Bulletins and Catalogues
Series 122, Number 16
September 5, 2026
S-Methyl Cysteine Sulfoxide: Its Effects On Cardiometabolic Outcomes In High-Fat Fed C57bl/6 Mice And Relevance To Human Health, Caroline R. Hill, Balmer, Hayley Abbiss, Jonathan M. Hodgson, Joshua R. Lewis, Armaghan Shafaei, Lauren C. Blekkenhorst
S-Methyl Cysteine Sulfoxide: Its Effects On Cardiometabolic Outcomes In High-Fat Fed C57bl/6 Mice And Relevance To Human Health, Caroline R. Hill, Balmer, Hayley Abbiss, Jonathan M. Hodgson, Joshua R. Lewis, Armaghan Shafaei, Lauren C. Blekkenhorst
Research outputs 2022 to 2026
S-Methyl cysteine sulfoxide (SMCSO) is an organosulfur compound with demonstrated hypocholesterolemic, anti-diabetic, and antioxidant benefits in rodents. However, the doses used have limited translatability for humans. We explored whether SMCSO could blunt development of diet-induced metabolic syndrome features in mice using doses that are potentially more translatable and achievable in humans. Male mice (C57BL/6; n = 54) were randomly assigned into one of five groups: [1] normal-diet; [2] high-fat-diet; or high-fat-diet with [3] 60 mg kg−1, [4] 170 mg kg−1, or [5] 350 mg per kg per body weight (BW) of SMCSO, respectively. Doses were administered …
Peptidomic Profiling Of In Vitro Digesta From Diverse Microalgae Species, Sara Hamzelou, Damien Belobrajdic, Henri Brook, Wei Chen, Fletcher Hiten, Kim Lee Chang, Diane Purcell, Utpal Bose, Simone Osborne, Cassandra Pegg, Michelle L. Colgrave
Peptidomic Profiling Of In Vitro Digesta From Diverse Microalgae Species, Sara Hamzelou, Damien Belobrajdic, Henri Brook, Wei Chen, Fletcher Hiten, Kim Lee Chang, Diane Purcell, Utpal Bose, Simone Osborne, Cassandra Pegg, Michelle L. Colgrave
Research outputs 2022 to 2026
Microalgae are a sustainable protein source, yet few species are used for human nutrition. This study evaluated eight species for protein quality, digestibility, and peptide profiles after simulated gastrointestinal digestion using INFOGEST. Amino acid content, and intestinal-phase peptide mixtures were analysed by mass spectrometry. The methanol precipitation method was used to separate digested (supernatant) and undigested (pellet) peptides following in vitro INFOGEST digestion. The pellet was further separated by molecular weight into 3–10 kDa and >10 kDa fractions to isolate the lower molecular weight peptides from the higher ones. This separation method enabled the identification of potential digested peptides within …