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Highly Variable Expressivity Of A Cnv Deletion Involving Tbx4 In Three Deceased Siblings With Lung Developmental Disorder And Their Mildly Affected Mother And Grandfather, Przemyslaw Szafranski, Tomasz Gambin, Michal Kadlof, Michał Denkiewicz, Dariusz Plewczynski, Hyun Jeong Kim, Gail Deutsch, Nahir Cortes-Santiago, Salmo Raskin, Paweł Stankiewicz

Faculty, Staff and Students Publications

Single nucleotide variants (SNVs) and copy-number variant (CNV) deletions involving TBX4 have been associated with pulmonary arterial hypertension, ischiocoxopodopatellar syndrome, and lethal lung developmental disorders (LLDDs). Thus far, all large CNV deletions encompassing entire TBX4 have been found to have arisen de novo. Here, we present a three-generation family with three neonate siblings who died within 35-66 days due to histopathologically diagnosed LLDD. Whole-genome sequencing identified an ~108-kb CNV deletion encompassing TBX4 in all three infants. The deletion was also found in their mother with a history of pneumonia and persistent thick upper airway secretions and in the maternal grandfather …

The Role Of Hospitality In Neurosurgery, Yosef M Dastagirzada, Howard L Weiner

Faculty, Staff and Students Publications

Background: "Business, like life, is all about how you make people feel. It's that simple and it's that hard" says Danny Meyer, the restauranteur and CEO of the Union Square Hospitality Group in New York. Similarly, Maya Angelou famously said that people will never forget how you made them feel, though they may forget what you said or did. In neurosurgery, we are doing two things at once: something very technical and something very human. The core thesis of this hospitality philosophy is that whereas the technical aspect of our job is critically important, it represents 49% of our success. …

Aerocom: Winter 2026, John D. Odegard School Of Aerospace Sciences

Aerocom: John D. Odegard School of Aerospace Sciences Alumni Magazine

No abstract provided.

Undergraduate Voice Students’ Understanding Of The Vocalize And Its Purpose, Natalie H. Bazemore

Honors College Theses

This research discusses undergraduate voice students' understanding of vocalizes and their purpose. To discuss this subject, a vocalize has been defined along with its purpose analyzed. By discovering what methods voice teachers are using to prescribe vocalizes tells us how they are educating their singers on developing technical singing skills. This research was collected through a survey conducted in Qualtrics and was shared via social media voice teacher forums and collegiate music settings. This 5-10 minute long survey included participants that are either undergraduate voice students or undergraduate voice teachers. The teachers and students completed different surveys, both asking about …

The Relationship Between U.S. Presidents And Governors From Opposing Political Parties: Policy Implementation And Crisis Management, Adam Richey

Honors College Theses

This thesis studies the impact of partisan divisions between U.S. presidents and state governors in regard to policy implementation and crisis management of the American federal system. While previous research has mainly addressed congressional polarization, executive relationships across different levels of government have received comparatively less scholarly focus.  Particularism theory argues that electoral incentives shape executive behavior, and this study finds that political alignment significantly affects cooperation, coordination, and responsiveness during times of crises. Focusing on qualitative comparative case study methods, the analysis examines Hurricane Katrina (2005) and the COVID-19 pandemic (2020–2021). The results show that partisan division most often …

Perinatal Inflammation And Oxidative Stress Alter Adult Rat (Rattus Norvegicus) Motor Behavior, Alexander Young

Honors College Theses

Recent evidence in comparative animal models suggests that early life exposure to elevated inflammation (via LPS exposure) and oxidative stress (via acetaminophen exposure) may synergistically interact to alter typical neurodevelopmental trajectories, resulting in lasting effects on both behavior and gut-brain neurochemistry. The current study observed emotional and motor behaviors and collected fecal-boli to measure Tyrosine (TE) levels in male and female Long-Evans (Rattus norvegicus) rats. Subjects were either treated with [1] saline [2] lipopolysaccharide (LPS) to introduce an inflammatory state, [3] acetaminophen (APAP) to introduce oxidative stress, or [4] a dual-hit of both LPS + APAP on postnatal day (PD) …

Exploring The Effects Of Mindset And Mood On Cognitive Performance, Pamela Kplivi

Honors College Theses

Individual and situational factors such as mindset and mood can shape performance on creative problem solving tasks. This study examined the potential effects of mindset (growth vs. fixed) and mood (positive, neutral, negative) on performance. Performance was measured using a shortened 60-item version of the Compound Remote Associates Task (CRAT; Bowden & Jung- Beeman, 2003). 92 undergraduate students completed self report measures of mindset (ITIS; Dweck, 1999) and self-efficacy (Schwarzer & Jerusalem, 1995). Participants were randomly assigned to a video-based mood induction condition and completed a self-reported mood survey (PANAS; Watson et al., 1988). Manipulation checks confirmed the effectiveness of …

The Role Of Mentorship In Reducing Burnout In New Nurses And Nursing Students, Omari Andry

Honors College Theses

Burnout among new nurses and nursing students is a consistent issue affecting the healthcare system by adding to early career turnover, emotional exhaustion, and decreased quality of patient care. Structured mentorship programs have emerged as a promising intervention to alleviate burnout by giving emotional support, professional development, and coping strategies. This proposal explores the role of mentorship in reducing burnout symptoms, improving job satisfaction, and promoting emotional resilience among new nurses and nursing students alike. Based on existing scholarly articles, the project will investigate how structured versus informal mentorship affects burnout rates, the qualities of effective mentors, and the outcomes …

What Is The Evolving Role Of Nurses In Telehealth As Future Healthcare Professionals?, Emma G. Lowry

Honors College Theses

Telehealth has evolved into an essential component of healthcare delivery in today's world, something that occurred alongside the COVID-19 pandemic. As healthcare professionals, nurses must be adequately prepared and equipped to use the tools for telehealth. This paper examines the evolving role of nurses in telehealth by assessing undergraduate nursing students’ and practicing nurses’ knowledge, attitudes, and perceived competencies. Data will be collected through a Qualtrics survey utilizing the Awareness, Knowledge, Attitude, and Skills (AKAS) Scale for Telemedicine, supplemented by interviews with telehealth practitioners to provide qualitative context. It is expected that variations in proficiency and attitudes, from previous biased …

Short Time, Lasting Impact: Teaching Pediatric End-Of-Life Care In One Day, Mckenzie Taliaferro

Honors College Theses

Background: Pediatric nurses working in specialties that experience terminal diagnoses, death, and post-mortem care, often feel unprepared for the emotional toll and lack adequate support systems (Camera et al., 2024). Nurses report feeling under prepared due to a lack of hands-on opportunities before graduation (Richoux, et al., 2022). Pediatric death is a traumatic experience for families and nurses. Previous studies have shown that hands-on education increases nurses' confidence in caring for patients at the end of their lives (Cole & Foito, 2019; Noyes et al., 2023). Method: A one-day, hands-on multidisciplinary workshop on pediatric end-of-life (EOL) was created and offered …

Development Of Tunable Rose Bengal Based-Nanogumbos As Potential Selective Chemotherapeutic Agents, William J.A. Russell

Honors College Theses

As cancer remains one of the greatest threats to the global population, the development of chemotherapeutic agents that are selective and tunable is of critical importance. Herein, a series of Rose Bengal (RB)-based GUMBOS, a group of uniform materials based on organic salts, were synthesized via counterion exchange between [Na]₂[RB] and three organic cations: tetrabutylphosphonium bromide [TBP][Br], tetraphenylphosphonium chloride [TPP][Cl], and 1-dodecyl-3-methylimidazolium chloride [C₁₂MIm][Cl]. The resulting GUMBOS were characterized through FT-IR, ESI-MS, NMR, and UV-Vis Spectroscopy. Partition coefficient studies indicated all GUMBOS exhibited hydrophobic physiochemical characteristics. These hydrophobic RB-based GUMBOS …

Effects Of Dietary Perfluorobutane Sulfonate (Pfbs) On Adipose Tissue, Hannah Olofintuyi, Eric Gato

Honors College Theses

Per- and polyfluoroalkyl substances (PFAS) are chemical substances used in a variety of industrial applications and consumer products. Perfluorobutane sulfonate (PFBS) is often used as a replacement for the more harmful (Perfluoroalkyl sulfonate) PFAS chemicals that have been around longer. It is believed that PFBS does not remain in the body as long as other PFAS compounds; however, there is a rising concern that it has the potential to cause damage to human health. This study focused on understanding how dietary PFBS exposure affects metabolism-related processes in adipose tissues in rats. To accomplish study objectives, Sprague Dawley rats were exposed …

From The Classroom To The Workplace: The Role Of Internships In Shaping Student Values, Jasmine Williams

Honors College Theses

A significant degree of research on workplace values has been conducted to better understand how employees are motivated in the hopes of reducing turnover. There also exists a significant body of literature on how internships impact career outcome and can effectively prepare students for the workforce. However, previous studies have not explored the differences between students who have completed internships in comparison to those who have not. The goal of this research is to determine whether internships create a significant impact on students’ workplace values (e.g. intrinsic, extrinsic, altruistic, and social) when compared to students who have not completed an …

Preventing Coccus Longulus Infestation, Nicholas Wellls

Honors College Theses

In the Armstrong greenhouse, the Coccus longulus scale insect is a prevalent problem on a specific species of Begonia known as Begonia ‘Richmondensis’. Inside the greenhouse there are several types of begonias with very similar characteristics to the Richmondensis begonia. However, none of these other begonias are infested by C. longulus, despite similar leaf thickness and environmental conditions such as humidity and light. This project examined whether differences in the chemical composition of the Begonia leaves can explain this pattern. Results were not statistically significant, but they showed that the chemicals had a noticeable impact on the scale, and …

Crisis Communication In The Influencer Era: A Crisis Response Analysis Of Poppi And Alani Nu, Meredith E. Staley

Honors College Theses

As social media continues to reshape modern public relations practice, beverage brands like Alani Nu and Poppi offer relevant examples of influencer-driven communication and crisis response. This honors thesis compares and contrasts these brands following two major crises: Poppi’s influencer vending machine campaign and the health concerns and backlash surrounding Alani Nu’s energy drinks. Despite the well-known prevalence of these brands, there is little scholarly research examining their crisis communication strategies. Guided by Situational Crisis Communication Theory, this study uses a combination of social and news media content analysis to evaluate how each brand responded to its respective crisis. Each …

How Is The Use Of Ai Impacting Nursing Students Education?, Lorna H. Strain

Honors College Theses

The use of Artificial Intelligence (AI) in education is rapidly increasing and reshaping how nursing students learn and engage with content. This thesis proposal looks at the impact of AI on the education of nursing students and explores students' perceptions of its use in their learning and education. As AI becomes more prevalent, many students are using it for study aids and content personalization, while schools are using it in simulations and textbook platforms. Many recognize its benefits, such as enhanced critical thinking, improved accessibility of materials, and more immersive learning. Concerns persist around ethical use, academic integrity, and the …

The Open Secret: Drugs And Fishing In Georgia, Makala L. Collins

Honors College Theses

Substance use and overdose deaths have been disproportionally disrupting families and communities in rural America. Increasing rates of drug use in these areas can be traced to the outsourcing of blue-collar work to outside of the United States, which economically restructured these areas by decreasing the profitability of generational industries. This is the story playing out in Georgia’s commercial shrimping industry and the communities it used to support. This research uses qualitative data collected over the past ten years to understand the perceptions and impacts of drug use on Georgia’s shrimping community. Using a lens of critical medical anthropology, environmental …

Validity Assessment Of Resting Heart Rate Variability From The Garmin Health Snapshot, Kayla M. Porter, Andrew Flatt

Honors College Theses

Purpose: To assess the agreement between the Garmin Forerunner 265 (a commercially available sports watch) and a single-channel electrocardiographic (ECG) chest strap for determining resting heart rate variability (HRV). Secondary aims were to assess the impact of skin tone and body position on measurement accuracy.

Methods: Young adults (n = 30, 57% women) aged 18–39 years without known cardiovascular conditions and without tattooing or scarring on the dorsal left wrist were recruited. HRV was recorded simultaneously using ECG and the Forerunner 265’s optical sensor during Garmin’s 2-minute “Health Snapshot.” Measurements were obtained in three standardized positions: supine, seated, and standing. …

The Sting Of The Women Airforce Service Pilots: The Fight For Militarization And Recognition, Cassandra Cates

Honors College Theses

The Women Airforce Service Pilots, commonly known as the WASPs, were the first women to fly military planes for the United States. Serving during World War II, the main goal of the WASPs was to relieve the men flying planes domestically, so the men could serve overseas. But despite their dedicated wartime service, negative press and an unfavorable Congressional investigation prevented the WASPs from being fully recognized in 1944, and consequently militarized. Once they were disbanded near war’s end, the WASPs returned to civilian life. Not until the 1970s did the WASPs start to speak out about their service and …

Perception Of Bsn Nursing Students On Theory-Practice Gap, Emmalyn G. Siclare

Honors College Theses

Nursing students obtain valuable experience and are greatly influenced by their clinical experience in nursing school. The continuity and translation of lecture content learned in nursing school to the clinical part of nursing school is known as the theory-practice gap, and it is a vital part of nursing students’ education that is suffering. A perceivable theory-practice gap has a profound effect on students’ readiness for entering the nursing profession. This study examines how the theory-practice gap is understood by Bachelor of Science in Nursing students, and solutions for how it can be remedied. A descriptive qualitative study was conducted to …

Exploring Academic Burnout In Georgia Southern University Nursing Students, Gwyneth A. Green

Honors College Theses

This project aims to explore the burnout that nursing students experience while going through nursing school. There are plenty of stressors that affect nursing students and their performance in the classroom, so the goal is to identify these stressors and find ways to cope with them to improve classroom performance and decrease the number of students who quit while in school. Finding ways to make nursing school a better experience overall will help improve the outcomes coming out of school and starting to work. A survey was given to research multiple cohorts in the Georgia Southern University Nursing program to …

Working Mule Or Sacrificial Lamb: Examining Agrarian Backlash And Populism In Rural Europe, Ava Elaine Rumsey

Honors College Theses

This thesis examines to what extent populism has become a political force across rural and agrarian communities in the European Union from 2023 to 2026. It distinguishes between ‘structural’ shifts, meaning the broader transformations in agrarian political economy, and ‘policy’ shifts, meaning the cumulative impact of Common Agricultural Policy (CAP) reform, notably its welfarist and regulatory priorities. This study draws on two types of evidence. First, it pulls from a wide range of secondary sources on the CAP and agrarian political transformation. Second, it analyzes the position papers, statements, and digital media of three organizations that represent important farming constituencies …

A Deal's A Deal: The Obvious Problem In Patent Law, Robin C. Feldman, Gideon Schor

Faculty Scholarship

Critics and industry alike agree that something is amiss in the market for medicines: Drug prices continue to rise, while various players point fingers, attributing the problem to different systemic inefficiencies. At the heart of this problem, however, lies the patent system, which provides the power that drives many of the strategic behaviors discussed in the literature.

A Deal’s a Deal suggests that a key element of patent law — obviousness doctrine — has been overlooked in the search for causes and solutions of the many distortions in pharmaceutical markets. This uniquely comprehensive Article examines obviousness doctrine from numerous angles: …

Exclusion By Design: Immigrant Racialization And Temporary Legal Status, Ming H. Chen, Jennifer M. Chacón, Shannon M. Gleeson

Faculty Scholarship

Migrant workers enter the United States on temporary visas more often than on green cards that lead to U.S. citizenship, and the majority come from countries whose emigrants would be classified as non-White in the United States. Even so, immigration scholarship gives short shrift to temporary statuses and often treats them as race neutral. This Article contributes to the growing body of critical migration studies by demonstrating how immigration law assigns meaning to the legal status of temporary migrants. We find that temporary legal statuses are designed in ways that unnecessarily foster social exclusion through a process of racialization and …

Are Iowa Pk-12 Schools Prepared For A School Shooting? A Needs Assessment Of Iowa Superintendents, Kurt Mj Devore

Dissertations and Theses @ UNI

As school shootings remain a persistent threat to PK-12 education, this quantitative survey study examines the preparedness levels and beliefs of 75 out of 277 Iowa superintendents regarding active shooter events. In the wake of the 2024 tragedy in Perry, Iowa, results indicate a near-universal recognition of risk (97.3%), prompting a shift toward "muscle memory" training and the adoption of the Standard Response Protocol (SRP) to ensure a common language during a crisis. The data reveals a significant move away from high-intensity simulations in favor of trauma-informed tabletop exercises, alongside a definitive rejection of arming educators (0%) due to insurance …

Test-Retest Apparent Diffusion Coefficient Reproducibility In Head And Neck Cancer Using A 15-T Mr-Linac, Brigid A Mcdonald, Dina El-Habashy, Renjie He, Sam Mulder, Sarah Mirbahaeddin, Abdallah S R Mohamed, Sara Ahmed, Yao Ding, Jihong Wang, Stephen Y Lai, Alex Dresner, John Christodouleas, Clifton D Fuller

Faculty, Staff and Student Publications

Purpose

To evaluate the reproducibility of apparent diffusion coefficient (ADC) measurements in head and neck squamous cell carcinoma (HNSCC) using a 1.5-T MR-linac (MRI-guided linear accelerator) system.

Materials and Methods

In this retrospective study, conducted between February 2021 and January 2024, patients with HNSCC lesions underwent echo-planar imaging diffusion-weighted MRI on a 1.5-T MR-linac system at two time points before the start of radiation therapy. Mean and median ADC values and volumes were measured for each lesion. Absolute and percent reproducibility coefficients (RCs) were calculated. Linear regression analyses and F tests were performed to determine whether the lesion volume or …

Access To Digital Health Technologies: Personalized Framework And Global Perspectives, Sanjiv M Narayan, Mina K Chung, Demilade Adedinsewo, Luisa C C Brant, Leslie L Davis, David Duncker, Jennifer L Hall, Janet K Han, Carolyn S P Lam, Eldrin Lewis, Joseph Loscalzo, Manlio F Márquez, Vasiliki Rahimzadeh, Fatima Rodriguez, Prashanthan Sanders, Emma Svennberg, Kenneth Stein, Mintu Turakhia, Clyde Yancy, Antonis A Armoundas

Center for Medical Ethics and Health Policy Staff Publications

The emergence and rapid adoption of digital health technologies (DHT) present unprecedented opportunities to democratize and reduce disparities in health care by monitoring health and disease at the point of care in all patients. However, limited access to DHT is becoming a major obstacle to realizing these goals. Access to DHT is influenced not only by well-recognized social determinants of health, but also by digital determinants of health, such as digital literacy and the need for broad access to digital infrastructure, as well as commercial and economic factors. Addressing these challenges and designing unbiased systems of care are essential to …