Digital Commons Network^™

Epinephrine In Cardiac Arrest: Is It Enough?, Zachary Gusler

The PA Department Journal of Medical Science

Introduction: Epinephrine has long been the clinical mainstay of pharmacologic treatment for cardiac arrest management. It provides both α- and β-adrenergic receptor activation. However, at higher dosages, it may lead to sympathetic overload, oxidative stress, and cardiac myocyte apoptosis. The purpose of this paper is to evaluate the rates of ROSC (return of spontaneous circulation) with in-hospital cardiac arrest between epinephrine monotherapy and VSE (vasopressin, steroid, and epinephrine).

Methods: A search via PubMed database using the keywords “Cardiac arrest” AND “VSE” AND “Vasopressor monotherapy” with additional specifiers resulted in 30 articles. 26 articles were removed due to study type and …

Efficacy Of Catheter Ablation Compared To Antiarrhythmic Drug Therapy In Atrial Fibrillation, Sarah Mckinney

The PA Department Journal of Medical Science

Introduction: A-fib occurs when the electrical signals in the heart become unorganized and unsynchronized, resulting in an irregularly irregular heart rate. This can increase the risk of blood clots and stroke. The purpose of this paper is to explore two of the most common treatment options, comparing the efficacy of catheter ablation to AAD (antiarrhythmic drug) therapy in adults diagnosed with atrial fibrillation.

Methods: PubMed was searched using the keywords “atrial fibrillation,” “catheter ablation,” and “antiarrhythmic.” Operators and filters yielded a final result of 159 articles; four articles that most closely aligned with the focus of this research were reviewed. …

Hyaluronic Acid Versus Corticosteroids In Osteoarthritis Of The Knee, Victoria B. Short

The PA Department Journal of Medical Science

Introduction: Osteoarthritis is a very common degenerative disease seen in older adults that is typically due to repetitive movements of the joints over time. Without treatment, osteoarthritis can progress and cause individuals to have decreased function and quality of life. The purpose of this review is to evaluate the effectiveness of hyaluronic acid injections compared to corticosteroid injections in treating osteoarthritis of the knee.

Methods: PubMed was searched with a specific search strategy using key terms “knee osteoarthritis”, “hyaluronic acid”, and “corticosteroids”. Operators and filters were applied to narrow 572 results down to 40. 15 articles were reviewed and 4 …

Injection Or Ingestion: A Comparative Review Of Antipsychotic Delivery Methods And Patient Outcomes In Schizophrenia, Jeffrey K. Fear

The PA Department Journal of Medical Science

Introduction: Schizophrenia is a chronic psychiatric disorder that causes significant functional impairment and decreased quality of life for those who suffer from it. The purpose of this review is to compare the use of long-acting injectable (LAIs) antipsychotics with oral antipsychotic medications and to evaluate which treatment modality provides more favorable outcomes in terms of symptom control, adherence, and relapse prevention.

Methods: PubMed was searched to find articles examining the efficacy of both long-acting injectables and oral antipsychotics, and why long-acting injectables are becoming the preferred method of delivering treatment to patients suffering from schizophrenia. Four articles were selected for …

Glp-1 Agonists For Pediatric Obesity: A Clinical Review, Grace Burgin

The PA Department Journal of Medical Science

Introduction: Pediatric obesity is a chronic disease with multiple complex causes and many potential consequences if carried into adulthood. Lifestyle modifications alone have not been effective for all patients in the treatment of pediatric obesity. GLP-1 RAs already being prescribed in the adult population were also recently approved for pediatric patients. The purpose of this clinical review is to analyze the efficacy of GLP-1 RAs in decreasing markers associated with obesity, such as BMI, cholesterol, etc. in pediatric patients diagnosed with obesity.

Methods: PubMed was first searched using synonyms of the keywords “pediatric obesity,” “GLP-1 agonists,” “lifestyle modifications,” and “biomarkers …

The Gut Microbiome’S Effect On Metabolic Syndrome, Kayla Turner

The PA Department Journal of Medical Science

Introduction: Metabolic Syndrome (MetS) is a chronic condition characterized by insulin resistance and low-grade inflammation. The purpose of this review is to focus on pre-/pro/symbiotic supplementation as a means of improving MetS parameters in place of pharmacological intervention.

Methods: PubMed was searched with the terms “metabolic syndrome”, “obese”, “obesity”, “overweight”, “insulin resistance”, “insulin sensitivity”, “probiotic”, “symbiotic”, and “bifidobacter*”. Operators and filters narrowed the results down to 55 results, 4 of which were picked due to their relevance and quality.

Results: The 4 articles chosen were RCT and a systematic review that explored the Bifidobacterium genus in relationship to the MetS …

Pharmacological Management Of A Spinal Cord Injury: A Review, Victoria A. Sumner

The PA Department Journal of Medical Science

Introduction

A spinal cord injury results from damage to the cord itself. People who experience such an injury often live with pain for the rest of their lives. This review aims to compare the effectiveness of gabapentin versus tramadol in managing post-spinal cord injury pain.

Methods

A search using the key terms “spinal cord injury,” “gabapentin,” and “tramadol” was conducted on PubMed. Five relevant results were identified after applying operators and filters to narrow down the articles. Of those five articles, four were reviewed in this analysis.

Results

All four articles directly compare gabapentin to a test substance. Three of …

Understanding The Efficacy Of Photodynamic Therapy In Comparison To Topical Therapies In Treating Actinic Keratosis In Those At Increased Sun Exposure Risk, Tatum R. Mcbride

The PA Department Journal of Medical Science

Introduction: Actinic keratoses are precancerous skin lesions that arise secondary to increased sun exposure. These lesions have a propensity to transform into non-melanoma skin cancers, mainly squamous cell carcinoma, if left untreated. There are a multitude of different treatment options for the prevention and clearance of these lesions. Among these options is photodynamic therapy (PDT). The purpose of this paper is to investigate the effectiveness of PDT when compared to other options for AK treatment.

Methods: A search was conducted using PubMed for studies to analyze the efficacy of PDT when compared to other treatment options. 3 articles were selected …

Psilocybin Treatment For Refractory Depression: A Clinical Review, Hailey A. Jensen

The PA Department Journal of Medical Science

Introduction:

Depression is a widespread mental illness that affects a large portion of the world population and many of those who suffer from depression are resistant to treatment currently available. The purpose of this review is to compare the efficacy of psilocybin to the current available methods for the treatment of refractory depression.

Methods:

PubMed was searched with the key search terms: resistant depression, psilocybin therapy, and adults. Operators and filters narrowed down the search to 43 results. Four articles were then chosen based on quality and specificity with this review.

Results:

The articles included in this review compare the …

Hyaluronic Acid For The Treatment Of Knee Osteoarthritis: A Clinical Review, Victoria G. Morrison Cerda

The PA Department Journal of Medical Science

Introduction: Osteoarthritis of the knee (KOA) is a progressive degenerative disease of the knee joint characterized by knee pain and limited knee function which negatively impacts activities of daily living. Effective and safe IA treatments are needed to meet the needs of an ever-increasing population of those living with KOA. This clinical review aims to assess the effectiveness of IA hyaluronic acid compared to corticosteroids for pain management in KOA.

Methods: PubMed was searched using the key terms “hyaluronic acid injection”, “knee osteoarthritis”, “corticosteroid injection”, and “pain relief”. Modifiers and operators were applied, and results were narrowed to four relevant …

Beyond Steroids: A Head-To-Head Review Of Hyaluronic Acid And Prp In Knee Osteoarthritis, Phillip A. Sekander

The PA Department Journal of Medical Science

Introduction: Osteoarthritis of the knee is one of the most common primary complaints in the US. Newer injectable therapies that target specific cartilage degeneration are being developed. The purpose of this review is to compare the efficacy of PRP and HA injections for the management of knee osteoarthritis.

Methods: PubMed was searched using the key terms “osteoarthritis of the knee,” “hyaluronic acid,” “platelet-rich plasma,” and “management of pain.” This search was refined using MeSH terms, Boolean operators, and applied filters (English, free full-text, publication date between 2020-2025). Four articles were selected for in-depth review of the efficacy of platelet-rich plasma …

Gluten-Free Diet For Patients With Hashimoto's Thyroiditis: A Clinical Review, Sallie Young

The PA Department Journal of Medical Science

Introduction: Hashimoto’s thyroiditis (HT) is the most common cause of hypothyroidism worldwide. Although levothyroxine remains the standard treatment for hypothyroidism caused by HT, interest has grown in dietary interventions, particularly gluten-free diets (GFDs), as a means of reducing thyroid autoimmunity and improving clinical outcomes. The purpose of this clinical review is to analyze the effectiveness of GFD on improving thyroid autoantibodies in patients with HT.

Methods: PubMed was search with a specific search strategy using key terms “Hashimoto’s thyroiditis”, “autoimmune hypothyroidism”, “Hashimoto’s” and “diet”. Operators and filters narrowed results to sixteen. Four studies met the inclusion criteria, including …

“I Don’T Always See A Future For Me Here”: Oppressive Political Pressures On Lgbtq+ College Students’ Well-Being, Jodi Linley, Olivia M. Copeland, Kathleen J. Buell, Cindy Ann Kilgo, Megan Pendleton, Alex C. Lange, N F. Tennessen

Journal of Queer and Trans Studies in Education

In recent decades, colleges have broadly supported LGBTQ+ students. Now, institutions have shuttered LGBTQ+ initiatives in response to political pressures, with little consideration for the effects on students. This study answers the question, what current policy factors do LGBTQ+ college students describe as affecting their well-being, and in what ways? We analyzed 426 responses from a multi-institution study of LGBTQ+ students. By and large, students feel anxious and fearful as they navigate the current climate. Our analysis illustrated numerous factors, from the President and his administration to states and general emboldened violence, and the real and potential consequences of those …

Facts, Policy, And Discretion, F. Andrew Hessick, Carissa Byrne Hessick

Faculty Publications

Presidents, prosecutors, and judges often announce policies on how they will make discretionary decisions. These policies have met the criticism that discretion must be the product of an assessment of the particular facts of a case. Decisionmakers cannot base discretionary decisions on policy considerations, nor can they adopt policies stating how they intend to exercise their discretion. To do so, the argument goes, does not constitute an exercise of discretion, but rather an abdication of it.

This Article argues that this criticism misunderstands discretion. Discretionary decisions must rest on reasons, and reasons necessarily appeal to principles and policies that are …

Teacher Perceptions Of Best Teaching Practices For Improved Student Outcomes In An Alternative School Setting, Chasity Clark

Doctor of Education Dissertations

This dissertation explores the experiences and professional perspectives of educators working in urban alternative school settings and examines how they foster positive outcomes for marginalized youth. Although alternative education is frequently characterized as a punitive “last resort,” this study highlights its potential as a setting for transformative resilience, student empowerment, and innovative teaching practices. Guided by social constructivism, transformative learning theory, and critical pedagogy, the study employed a qualitative design involving two rounds of semi-structured interviews and a focus group with 11 educators. Analysis of the data resulted in six integrated themes: psychological safety as a prerequisite for agency, self-efficacy …

An Exploratory Study In Sports Geography: The Interaction With The Environment And Sense Of Place In Endurance Running Events, Jackson Steffener

Dissertations and Theses @ UNI

This study examines how endurance running shapes runners' sense of place through interactions with physical environments, social dynamics, and embodied experience. With sports geography, it explores how participants form emotional and spatial connections to race settings while moving through varied landscapes under physical strain. A phenomenological multi-site case study design was used, focusing on four endurance events in Iowa that differed in terrain, setting, and structure.

Data were collected from 46 participants using mental mapping and semi structured field notes. Mental maps identified meaningful locations along race courses, while field notes captured emotional responses, environmental conditions, and social interactions. Thematic …

Annual Reports Of The Town Of Seabrook, New Hampshire For Year Ending December 31, 2025 As Compiled By Town Officers, Seabrook Town Representatives

Seabrook, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Expression Pattern Of The Hifα-Family In Equine Chorioallantois During Pregnancy And Placental Pathology, Yatta Boakari, Hossam El-Sheikh Ali, Gustavo Henrique Doná Rodrigues Almeida, Kirsten E. Scoggin, Claudia Barbosa Fernandes, Sophia Panelli Marchio, Mats H. T. Troedsson, Ana Claudia Oliveira Carreira

Maxwell H. Gluck Equine Research Center Faculty Publications

Equine placental dysfunction impairs fetal growth and disrupts pregnancy outcomes. Despite many advances in diagnosis, the molecular pathophysiology of equine placentitis and premature placental separation remains poorly understood. However, the hypoxia-inducible factor (HIF-α) pathway is related to placental hypoxia, and its modulation in placental diseases has been shown in other species. Therefore, we hypothesized that in conditions marked by equine placental dysfunction, oxygen deprivation in the chorioallantois membrane triggers the activation of the HIF-α pathway, which is related to molecular alterations associated with placental insufficiency. Accordingly, we compared the expression of HIF1A, HIF2A, HIF3A, and HIF1AN genes in equine chorioallantois …

Living The American Dystopia: Parallels Between Louise Erdrich's Future Home Of The Living God, Leni Zumas's Red Clocks, And Us Abortion Legislation, Erin R. Walden

Graduate Student Theses, Dissertations, & Professional Papers

This thesis highlights the parallels between contemporary U.S. culture and legislation (particularly after the overturning of Roe v. Wade) and two pieces of feminist speculative fiction: Louise Erdrich’s novel Future Home of the Living God and Leni Zumas’s Red Clocks. Through a rhetorical analysis of political and cultural discourse, legislation, and the two novels, utilizing the frameworks of theorists such as Catharine MacKinnon, Michel Foucault, and Stacy Alaimo, I investigate the similarities in legislation, culture, rhetoric, and atmospheres of reproductive dystopian fiction and our current political environment after the U.S. Supreme Court case Dobbs v. Jackson Women’s Health …

Adults With Dyslexia: Experiences Accessing And Using Reading Strategies And Assistive Technology, Brenda Rosalie King

Graduate Student Theses, Dissertations, & Professional Papers

Dyslexia is a specific learning disorder of neurobiological origin characterized by persistent difficulties with accurate and/or fluent reading, word recognition, spelling, and decoding. Although dyslexia is widely recognized as a lifelong learning difference, the majority of research has historically focused on children and adolescents, with less attention given to adult experiences. The purpose of this study was to explore how adults with dyslexia access and use reading strategies and assistive technologies to support reading comprehension and independence across contexts. The study also examined barriers and supports influencing access to these tools, as well as the emotional experiences associated with their …

Expectations In The Preservation Of Dna And Bacterial Organisms In Differential Montana Burials, Kaylee M. Hinds

Graduate Student Theses, Dissertations, & Professional Papers

This study investigates patterns of decomposition and biomolecular preservation in domestic pig (Sus scrofa domesticus) proxies under varying burial conditions in a cold, seasonal climate. Conducted at the Lubrecht Experimental Forest in western Montana, the project aims to evaluate DNA degradation, microbial activity, and environmental influences across shallow, deep, surface, and secondary burial contexts. Three pigs were placed in distinct burial treatments (surface exposure, partial burial, and full burial), with a fourth site later added following bear disturbance and carcass relocation. Environmental monitoring included temperature, and soil sampling before and throughout the decomposition process. Systematic sampling of bone, soft tissue, …

An Ecology Of Small Sorrows: Small Animals And The Fragile Ecosystems Inside Us, Haley H. Yarborough

Graduate Student Theses, Dissertations, & Professional Papers

In An Ecology of Small Sorrows, Haley Yarborough uses a series of personal essays to explore how encounters with small life shape her understanding of herself. This collection is inspired by many talented writers — Lucy Cooke’s insights into animal biology, Andy Weir’s humor and knack for explaining complicated topics, Ben Goldfarb’s insightful exploration of the overlooked, and Sabrina Embler’s beautiful, poetic reflections on the natural world.

These essays touch on how small animals serve as mirrors for us, through our experiences with illness, loss, insecurity, and survival. While a lot of modern media emphasize larger, charismatic species to tell …

Advancing Understanding Of Lived Experience Of Unhoused People To Reduce Social Stigma And Promote Community Health: A Theoretically-Guided Photovoice Study, B-Rad Stephen Applegate

Graduate Student Theses, Dissertations, & Professional Papers

Homelessness is a persistent public health challenge shaped by structural inequities, stigma, and exclusion from social and health systems. Community-Based Participatory Research (CBPR) has increasingly been used to center the knowledge of people who are unhoused, yet limited attention has been given to the theoretical frameworks guiding this work across disciplines. The purpose of this dissertation was to examine theories and methods used in CBPR with unhoused populations and to explore the extension of Margaret Newman’s Theory of Health as Expanding Consciousness from a nursing-focused theory to a public health framework for understanding lived experience.

Using a scoping review methodology …

Embodied Women’S Health In The Pacific: Biocultural Pathways Of Hormones, Immunity, And Reproduction, Courtney Callidora Manthey

Graduate Student Theses, Dissertations, & Professional Papers

This dissertation examines women’s health through a biocultural framework that integrates biological anthropology, medical anthropology, and public health, with a central focus on the Pacific. It advances embodiment theory as a unifying approach for understanding how lived experience becomes biologically incorporated across the life course, shaping reproductive, endocrine, and immune outcomes. Grounded in research in Sāmoa and situated within broader comparative contexts in the United States and Amazonian populations, this work argues that women’s health cannot be fully understood through biomedical indicators alone, but must instead be interpreted within historically, culturally, and environmentally embedded Pacific contexts and beyond. The dissertation …

Pestilent Air, Contagious Evil: Infectious Disease In Early Modern Poland, Danielle Marie Airola

Graduate Student Theses, Dissertations, & Professional Papers

The individuals buried in the cemetery of Czysty Square and the population of the vanished village of Gać lived and died during the early modern period in what is now modern-day Poland. Epidemics broke out repeatedly during this time, and the skeletal remains of several individuals buried in Czysty Square’s cemetery display pathological changes suggestive of infectious disease. These non-specific morphological changes created a need for DNA testing to search for pathogens associated with these lesions. In contrast, Gać’s population declined over time until the village’s abandonment. This has led to a hypothesis of an epidemic having contributed to the …

From Mandate To Implementation: A Qualitative Content Analysis Of Early Childhood Coursework In Educational Leadership Preparation Programs, Anna Louise Puryear

Graduate Student Theses, Dissertations, & Professional Papers

Research on principal leadership in the P-3 continuum is limited, even though leadership is second only to teaching in its impact on student outcomes. Most leadership preparation programs emphasize K–12 content, with little focus on early childhood education. Illinois is the only state to codify legislation requiring early childhood content in educational leadership programs, offering a unique case to examine how such mandates are implemented. This study employed qualitative content analysis to investigate how institutions of higher education represent mandated early childhood content in graduate-level coursework. Data sources included program-level documents from 22 Illinois leadership preparation programs and course-level materials …

Promoting Hope And Resilience: Measuring The Psychological Effects Of An Undergraduate Climate Change Education Course, Clare Bridgett Maguire

Graduate Student Theses, Dissertations, & Professional Papers

The psychological effects of climate change are increasing, which has led to an increase in advocacy to research these effects. Current literature has included a focus on categorizing and understanding the psychological impacts, creating psychometrically sound instruments to measure the effects, and education as a tool to enhance coping strategies. However, limited research exists on measuring the emotional outcomes for students who engage in climate change education at the post-graduate level.

This dissertation explores the effects of an undergraduate-level climate change course on participants’ experiences of eco-anxiety, ecological grief, resilience, and hope to better understand the psychological effects of climate …

Ghostly Grieving In Theatre’S Now Also The Dramaturgy Of Perception And The Body In Contemporary American Ghost Plays, Jacob Mann Christiansen

Graduate Student Theses, Dissertations, & Professional Papers

“Ghostly Grieving in Theatre’s Now Also” explores how contemporary American plays and playwrights stage the dead as a way of understanding theatre’s unique language for dealing with the shared, complex human experience of grief. Focusing on theatrical ghosts and other “impossible” presences, I articulate how these figures function as dramaturgical devices. I also argue that theatre’s ghosts “set the stage” (as it were) for communicable meaning-making by inviting audiences into the tasks of creation and mourning.

My work draws on performance theory (especially phenomenological accounts of theatrical storytelling), on dramaturgical analysis, and on grief studies. In this dissertation project, I …

Developing Identity After Goodbye: Social Identity Theory And How Adolescent Survivors Navigate Suicide Loss, Elizabeth Susan Lawton

Graduate Student Theses, Dissertations, & Professional Papers

Adolescents who lose a loved one to suicide, known as suicide-loss survivors, face a disruption to identity development, a life stage defined by identity formation (Adler et al., 2018) and group belonging (Pittman & Richmond, 2008). Suicide bereavement is complicated not only by grief but also by stigma, which can fracture social ties and undermine self-concept. Social identity theory (SIT) provides a framework for examining how young adults, now ages 18 to 30, reconstruct their social identities after experiencing suicide loss in adolescence. Research in other stigmatized contexts shows that adopting positive in-group identities can buffer against stigma and protect …

Á’Po’Taki Iiyika’Kimaa Work/Try Hard For Such A Time As This, Misamsai’Piaakíí Longtime Charging Woman Kimberly Lynn Paul

Graduate Student Theses, Dissertations, & Professional Papers

This body of work adds to a recent shift in the academic landscape, valuing interdisciplinary research and Indigenous worldview. Predominant is the reversal of extractive research norms within Indigenous populations and the biosystems they steward, instead claiming Piikani (Blackfeet) led community-needs-based research valuing Indigenous data sovereignty, research methodologies, ethics, equity, and Indigenous empowerment. This research proffers requisite historical information providing the ‘why’ context, followed by three of the author’s studies: in toxic dumping, food sovereignty, and Piikani well-being. Under an environmental justice framework, the first study presents a cursory investigation of decades-long illicit toxic waste disposal reports linked to observed …