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Articles 51361 - 51390 of 51489
Full-Text Articles in Entire DC Network
The Proposed Impact And Anticipated Barriers Of Establishing Food Action Groups In Rural, Regional, And Remote Western Australia, Stephanie L. Godrich, Jess Doe, Sarah Goodwin, Melissa Stoneham, Amanda Devine
The Proposed Impact And Anticipated Barriers Of Establishing Food Action Groups In Rural, Regional, And Remote Western Australia, Stephanie L. Godrich, Jess Doe, Sarah Goodwin, Melissa Stoneham, Amanda Devine
Research outputs 2022 to 2026
Objective: To identify Food Action Groups’ activities that positively impact local food systems, and anticipated barriers to establishing Food Action Groups in rural, regional, and remote Western Australia. Design: This qualitative study employed a phenomenological approach. Nineteen focus groups were conducted. Setting: Rural, regional, and remote Western Australia locations, including 11 towns across 8 regions. Participants: A total of 92 participants (61 interest holders and 31 community members). Analysis: A thematic analysis was undertaken. Results: Priority activities included government advocacy to support local commercial food production, processing, and sales; retain food within its region of origin; and home and community …
User Experience In Virtual Self-Disclosure: Appraising Natural, Urban, And Artificial Vr Environments, Shane L. Rogers, Tasha Canes, Alexis Pallister
User Experience In Virtual Self-Disclosure: Appraising Natural, Urban, And Artificial Vr Environments, Shane L. Rogers, Tasha Canes, Alexis Pallister
Research outputs 2022 to 2026
Featured Application: This study informs the design of virtual environments for therapeutic and emotionally meaningful conversations delivered through VR platforms. The findings show that nature-themed environments, particularly virtual blue spaces, can enhance users’ comfort and calmness when disclosing personal experiences. These results can guide developers of VR counselling systems, digital mental-health tools, and conversational-agent platforms in selecting or tailoring virtual environments that promote psychological safety and ease of communication. Virtual reality (VR) offers new opportunities for delivering psychologically meaningful conversations in digitally mediated settings. This study examined how environmental designs influence user experience during emotionally relevant self-disclosure. Fifty university students …
The Nature Of Agency: Designing Agentic Systems Using A Biomimetic Lens, Tegwen Malik, Laurie Hughes, Yogesh K. Dwivedi, Natalie De Mello, Igor Barahona, Il Jeon
The Nature Of Agency: Designing Agentic Systems Using A Biomimetic Lens, Tegwen Malik, Laurie Hughes, Yogesh K. Dwivedi, Natalie De Mello, Igor Barahona, Il Jeon
Research outputs 2022 to 2026
Purpose: This paper aims to explore how biomimetic principles can inform governance models for agentic artificial intelligence (AI) systems, autonomous, adaptive entities that challenge traditional oversight frameworks. It argues that nature-inspired governance offers a dynamic alternative to static, compliance-based models. Design/methodology/approach: This study adopts a conceptual viewpoint approach. It synthesizes literature on AI governance, systems theory and biomimicry, applying thematic analysis to existing frameworks and mapping identified gaps to five natural principles: symmetry, fractals, cymatic feedback, self-organization and phase transitions. Findings: Current governance frameworks lack mechanisms for managing emergent behaviors and distributed agency in agentic AI. The proposed biomimetic lens …
Tour Guide Research Revisited: A Thematic Synthesis And Future Directions, Zhicheng Yu, Songshan (Sam) Huang, Jiqing Deng, Wenling Zhou, Zhiyong Li
Tour Guide Research Revisited: A Thematic Synthesis And Future Directions, Zhicheng Yu, Songshan (Sam) Huang, Jiqing Deng, Wenling Zhou, Zhiyong Li
Research outputs 2022 to 2026
Purpose: Existing knowledge on tour guiding is fragmented, which limits the understanding of this important profession. This paper aims to critically examine the progress of tour guide research, identify key theoretical tensions and propose future research directions based on a systematic synthesis of existing knowledge. Design/methodology/approach: A thematic analysis was conducted on 267 papers retrieved from the Web of Science Core Collection, Scopus and Google Scholar databases. Papers were systematically coded, categorized into themes and integrated into a framework that represents relationships among key themes in tour guide research. Findings: The analysis generated an integrated framework consisting of nine interrelated …
Aerobic Exercise Increases Brain-Derived Neurotrophic Factor (Bdnf) In Sub-Acute Stroke: A Randomized Controlled Trial, Christopher P. Mackay, Suzanne Kuys, Mia Schaumberg, Li Ann Leow, Sandy Brauer
Aerobic Exercise Increases Brain-Derived Neurotrophic Factor (Bdnf) In Sub-Acute Stroke: A Randomized Controlled Trial, Christopher P. Mackay, Suzanne Kuys, Mia Schaumberg, Li Ann Leow, Sandy Brauer
Research outputs 2022 to 2026
Background: Brain-derived neurotrophic factor (BDNF) is a key neurotrophin due to its role in neuron process outgrowth, plasticity, and neuronal survival. Aerobic exercise can induce BDNF release and may ultimately maximize post-stroke recovery. Objectives: This study aimed to determine if a program of moderate-to-high-intensity aerobic exercise increased concentrations of BDNF in subacute stroke survivors compared to usual care. Methods: A parallel-group, RCT was undertaken in people with subacute stroke undergoing rehabilitation. Participants were randomly allocated to usual care (control group) or usual care plus an 8-week program of moderate-high intensity treadmill walking (3 x 30 min sessions per week) (experimental …
Feeling Giggity: Ambiguous Emojis In Teaching And Learning Communications, Mary Kynn, Nicole Reinke, Eva Hatje
Feeling Giggity: Ambiguous Emojis In Teaching And Learning Communications, Mary Kynn, Nicole Reinke, Eva Hatje
Research outputs 2022 to 2026
There is an increase in the number of digital platforms used in higher education classrooms that promote using emojis to capture students’ emotions. However, there is little evidence to suggest that interpretation of emojis is reliable in this context. This pilot project explored if emojis can reliably signify the emotions expressed by first-year university students. Students were asked to record their emotions by selecting a representative emoji and using free text to describe its meaning. A total of 72 responses were recorded in an anonymous online survey. Happy face emojis were used more frequently than emojis representing neutral or unpleasant …
Importance Of Strength Training To Prevent Secondary Lower Limb Musculoskeletal Injury In Military Personnel, Peter Ladlow, Russell J. Coppack, Robyn P. Cassidy, Rachel Rodgers, Robert Barker-Davies, Paul Comfort, Nicholas J. Ripley, Christopher Bramah, Colin Suffield, Debra Hayhurst, Marina De Vecchis, Samual R. Higgins, Alexander N. Bennett, Oliver O’Sullivan
Importance Of Strength Training To Prevent Secondary Lower Limb Musculoskeletal Injury In Military Personnel, Peter Ladlow, Russell J. Coppack, Robyn P. Cassidy, Rachel Rodgers, Robert Barker-Davies, Paul Comfort, Nicholas J. Ripley, Christopher Bramah, Colin Suffield, Debra Hayhurst, Marina De Vecchis, Samual R. Higgins, Alexander N. Bennett, Oliver O’Sullivan
Research outputs 2022 to 2026
Considerable operational and financial costs are associated with musculoskeletal injury (MSKI) across military organisations. Following an MSKI, reaching ‘medically fully deployable’ status is often contingent on meeting physical employment standards. Strength training has a critical role to play in military physical preparation, injury mitigation and guiding rehabilitation practice. Low levels of muscle strength are associated with increased MSKI risk, and previous MSKI is a leading risk factor for re-injury. When an MSKI does occur, it is essential that all attempts to mitigate the risk of secondary MSKI are met. Maximal force (muscle strength) and rapid force (rate of force development …
Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan
Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan
Research outputs 2022 to 2026
This study manipulated the blood pH of participants to be mildly acidic or basic prior to passive hyperthermia to examine its effects on thermoregulatory and chemo-regulatory responses, including ventilatory parameters, rectal temperature (Tre) and thermal perception. Twelve healthy males attended three experimental sessions in a double-blind, randomised, counterbalanced design. Passive hyperthermia was induced by hot water immersion at 40°C following the consumption of corn starch (placebo; PLA), ammonium chloride (AC) or sodium bicarbonate (SB). Compared with PLA, SB consumption increased blood pH and HCO3−, whilst AC decreased both blood pH and HCO3− (all P < 0.001). Specifically, minute ventilation was unchanged following SB (11.0 ± 3.7 L min−1) but …
International Cardiac Advanced Life Support Course: A Cross-Sectional Descriptive Analysis, Nilufeur Mckay, Jody Ede, Jessica Stokes-Parish, Adrian Levine, Helen Walthall, Debbie Massey
International Cardiac Advanced Life Support Course: A Cross-Sectional Descriptive Analysis, Nilufeur Mckay, Jody Ede, Jessica Stokes-Parish, Adrian Levine, Helen Walthall, Debbie Massey
Research outputs 2022 to 2026
Background: Recognising and responding to cardiac surgical deterioration requires a systematic, structured approach that encompasses monitoring, identifying and managing signs and symptoms of post-surgical complications. Cardiac Advanced Life Support (CALS) was originally developed in recognition of this educational requirement and consists of a series of protocols aimed at supporting clinicians’ recognition and response to the deteriorating cardiac surgical patient. Aim: The aim of this analysis was to evaluate participant perceptions of a CALS course using a descriptive online survey. Design: A cross-sectional analysis of post-course online survey responses assessing participant’ perceptions of the CALS course. Results: 331 surveys were returned …
Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic
Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic
Research outputs 2022 to 2026
Background: Nicotinamide adenine dinucleotide (NAD+) is a cofactor for NAD+-dependent enzymes that regulate DNA repair, cellular metabolism, and immune function. Supplementation with NAD+ and its precursors is commonly used to prevent age-related disease and extend healthspan. Commercial clinical and wellness settings increasingly provide intravenous (IV) NAD+ and nicotinamide riboside (NR) despite limited evaluation of safety and effectiveness. These considerations are important, as NAD+ and its precursors differ in reported side effects, cellular uptake, and metabolism. This study sought to compare commercially administered NAD+ IV and NR IV in humans by evaluating infusion …
Midwifery Students' Definitions Of Normal Labor And Birth: A Study From Five Countries, Jalana Lazar, Juliet Wood, Jane Fry, Barbara Baranowska, Urszula Tataj-Puzyna, Debora Dole, Emma Ritchie, Clare Davison, Cindy L. Farley, Felicity Agwu Kalu, Maria Healy, Maria Węgrzynowska
Midwifery Students' Definitions Of Normal Labor And Birth: A Study From Five Countries, Jalana Lazar, Juliet Wood, Jane Fry, Barbara Baranowska, Urszula Tataj-Puzyna, Debora Dole, Emma Ritchie, Clare Davison, Cindy L. Farley, Felicity Agwu Kalu, Maria Healy, Maria Węgrzynowska
Research outputs 2022 to 2026
Introduction: Internationally, many women and birthing people are receiving maternity care interventions as a routine with no medical indication for their use. This medicalized environment influences midwives' practice and, by extension, midwifery students' clinical learning experiences, gaining knowledge and confidence in facilitating normal labor and birth. To educate midwifery students in the provision of high-quality maternal and newborn care, it is important to explore their understanding of normal labor and birth, as this underpins their philosophy of care and will inform their future practice. Methods: An online survey was developed from a review of current evidence. Following ethical approval, the …
Personal Family-Centred Care For Lgbtq+ Individuals In Acute Hospital Settings: A Scoping Review, Gideon U. Johnson, Bianca Ysabelle Esmeralda, Stephen Pearson, Beverley Ewens, Louise Rose
Personal Family-Centred Care For Lgbtq+ Individuals In Acute Hospital Settings: A Scoping Review, Gideon U. Johnson, Bianca Ysabelle Esmeralda, Stephen Pearson, Beverley Ewens, Louise Rose
Research outputs 2022 to 2026
Aim: To identify and synthesise existing evidence on family-centred care for Lesbian, Gay, Bisexual, Transgender, Queer and other diverse identities (LGBTQ+) people in acute hospital settings, including hospital-based palliative care, oncology, general in-patient and intensive care. Design: A scoping review guided by the JBI methodology. Methods: Nine databases and grey literature sources were searched. Inclusion criteria focused on LGBTQ+ adults and family-related care experiences in hospital-based acute settings. After screening, qualitative, quantitative, and narrative data were extracted. Thematic analysis synthesised findings, with quantitative data narratively integrated. Data Sources: Searches were conducted across nine databases and grey literature up to April …
Preparation Of Australian Nurses For Contemporary Disability Care: A Desktop Review, Lesley Andrew, Martina Costello
Preparation Of Australian Nurses For Contemporary Disability Care: A Desktop Review, Lesley Andrew, Martina Costello
Research outputs 2022 to 2026
Approximately 18% of Australians experience disability, with significant health inequities documented in this population. Despite nursing’s crucial role in addressing these inequities, questions remain about nurses’ preparedness to work effectively with people with disability. The review assessed Australian nursing education’s approach to prepare its graduate nurses for disability care in today’s Australia. Using a rigorous desktop analysis methodology, the review evaluated the publicly available undergraduate nursing degree curricula materials from all 32 Australian public universities that offered a preregistration nursing degree in 2024. The review found 50% of nursing degree curricula course materials omitted to mention disability in their publicly …
Sustainable Healthcare In Action: Six Practice Changes That Make A Difference, Christine Catling, Carol Crevacore, Melisa Young, Wayne Varndell, Jack Cornish, Sue Sheppard-Law, Elaine Correia Moll
Sustainable Healthcare In Action: Six Practice Changes That Make A Difference, Christine Catling, Carol Crevacore, Melisa Young, Wayne Varndell, Jack Cornish, Sue Sheppard-Law, Elaine Correia Moll
Research outputs 2022 to 2026
Problem: Planetary health, linking the well-being of human populations with the stability of Earth's natural systems, is increasingly recognised as essential for all organisations. Healthcare is a major contributor to environmental harm, responsible for an estimated 4.4% of global net emissions. As a result, healthcare workers have an important role in driving sustainable, low-waste practices within clinical settings. Aim: This paper outlines six practical, evidence-informed changes that can be introduced within healthcare organisations: adopting reusable tourniquets, reducing unnecessary glove use, recycling medication blister packs, promoting reusable nappies, using reusable or compostable blueys, and reintroducing stainless steel holloware. Discussion: These examples …
Sustaining Caring Mobilities In Immobility Regimes: Adaptive Strategies Of Vietnamese Migrant (Grand)Parents In Australia, Hien Thi Nguyen, Catriona Turnbull, Loretta Baldassar
Sustaining Caring Mobilities In Immobility Regimes: Adaptive Strategies Of Vietnamese Migrant (Grand)Parents In Australia, Hien Thi Nguyen, Catriona Turnbull, Loretta Baldassar
Research outputs 2022 to 2026
(Grand)parents are increasingly traveling internationally to visit and spend time with their transnational families. This mobility is essential to provide informal, unpaid care, driven by globalisation as family members relocate for study and work. However, governments in receiving countries like Australia are implementing restrictive measures, defined in the literature as ‘immobility regimes’, to control the movement of older migrants into their territories, including overseas (grand)parents. Drawing on the lived experiences of 22 Vietnamese migrants (11 (grand)parent visitors and 11 adult migrants who host their (grand)parent visitors), this paper explores the relationship between transnational mobility and institutional migration policies in the …
Triglyceride Glucose Index And Modified Triglyceride Glucose Indices Are Instrumental To Optimize 3p Medical Management For Postpartum Cardiovascular Disease, Dong Lin, Haoxian Tang, Enoch Odame Anto, Yueran Zhou, Shenglan Zhang, Xiulian Deng, Cuihong Tian, Weijie Cao, Zhuoqiao He, Zhisheng Chen, Pengxiang Ying, Yequn Chen, Xuerui Tan
Triglyceride Glucose Index And Modified Triglyceride Glucose Indices Are Instrumental To Optimize 3p Medical Management For Postpartum Cardiovascular Disease, Dong Lin, Haoxian Tang, Enoch Odame Anto, Yueran Zhou, Shenglan Zhang, Xiulian Deng, Cuihong Tian, Weijie Cao, Zhuoqiao He, Zhisheng Chen, Pengxiang Ying, Yequn Chen, Xuerui Tan
Research outputs 2022 to 2026
Background: Postpartum cardiovascular disease (CVD) following hypertensive disorders of pregnancy (HDP) involves multifactorial mechanisms linking metabolic susceptibility to vascular damage. Identifying predictive biomarkers and modifiable risk factors is crucial for early stratification in the context of predictive, preventive, and personalized medicine (PPPM). We aimed to investigate the association of triglyceride-glucose (TyG) indices with incident CVD in women with prior HDP and to assess the causal relationship using Bayesian weighted Mendelian randomization (BWMR) analysis, with a focus on the implications for PPPM strategies in postpartum management. Methods: In this longitudinal cohort study, 1,642 women with prior HDP from the UK Biobank …
What Is Resistance Exercise? A Review Of Current Uses And Potential Ways Forward, Lars H. Lohmann, José Afonso, David G. Behm, Stanislaw D. Siegel, Michael Keiner, Klaus Wirth, Anthony J. Blazevich, Eric R. Helms, Alyssa Joy Spence, Konstantin Warneke
What Is Resistance Exercise? A Review Of Current Uses And Potential Ways Forward, Lars H. Lohmann, José Afonso, David G. Behm, Stanislaw D. Siegel, Michael Keiner, Klaus Wirth, Anthony J. Blazevich, Eric R. Helms, Alyssa Joy Spence, Konstantin Warneke
Research outputs 2022 to 2026
The resistance exercise (RE) literature highlights the importance and impact of RE in sports performance, daily life, and clinical outcomes. While RE research dates back to the 19th century, current definitions of what constitutes RE are varied and give rise to questions about the requisites of RE. For example, some definitions refer to movements or muscle contractions against external resistance whereas others consider all repeated actions against one’s bodyweight. Taken to the limit, this could introduce confusion between RE and endurance exercise, for example. Without a clear definition, systematic reviews (with meta-analysis) discuss outcomes of studies examining the effects of …
When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke
When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke
Research outputs 2022 to 2026
Objective: Sporadic late-onset Alzheimer's disease (AD) is characterized by a long pre-clinical phase where amyloid-beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ-PET) and plasma Aβ42/40 become abnormal. Methods: Two high performance immunoprecipitation-mass spectrometry (IP-MS) assays (WashU/C2N and Shimadzu) were tested on samples from 1,450 participants who were diagnosed as cognitively unimpaired (CU), mild cognitive impairment (MCI), or AD-dementia across 4 international cohorts. Natural history modeling and trajectory analyses of the combined Aβ-PET …
Participatory Development Of Innovation And Implementation Strategy: An Action-Oriented Approach, Miae Lee, Lesley A. Anderson, Emilia Piltonen, Abha Maheshwari, Julian Griffin, Seshadri S. Vasan
Participatory Development Of Innovation And Implementation Strategy: An Action-Oriented Approach, Miae Lee, Lesley A. Anderson, Emilia Piltonen, Abha Maheshwari, Julian Griffin, Seshadri S. Vasan
Research outputs 2022 to 2026
Background: Healthcare and academic institutions face growing challenges in strategic planning due to rapid advances in medicine and technology, alongside fiscal and workforce constraints that limit traditional consultation. Participatory approaches offer a way to integrate diverse stakeholder perspectives under these constraints, generating contextually relevant strategies that can indicate whether current directions are appropriate or whether priorities have been overlooked.
Methods: A structured, time-limited participatory workshop was conducted at the 10th Grampian Research Conference (June 2025), that brought together National Health Service (NHS) staff, academia, industry and patients and public communities. Participants engaged in 14 parallel roundtable discussions, with contributions captured …
Noongar Culture, Arts Learning, And Wellbeing Literacy In Early Childhood: A Case Study Of The Song Room’S Deadly Arts Early Years Program In Western Australia Government Primary Schools, Jason Goopy, Narelle Lemon, Megan Mcpherson, Libby Jackson-Barrett, Jacqueline West
Noongar Culture, Arts Learning, And Wellbeing Literacy In Early Childhood: A Case Study Of The Song Room’S Deadly Arts Early Years Program In Western Australia Government Primary Schools, Jason Goopy, Narelle Lemon, Megan Mcpherson, Libby Jackson-Barrett, Jacqueline West
Research outputs 2022 to 2026
This report presents findings from a case study examining how The Song Room's Deadly Arts Early Years program supports wellbeing literacy in early childhood education through engagement with Noongar culture, arts, and storytelling at Western Australia government primary schools. Conducted on Whadjuk Noongar Boodjar at Huntingdale Primary School and Orelia Primary School, the research was co-designed with Indigenous and non-Indigenous teaching artists, school communities, and The Song Room.
The study adopted wellbeing literacy — the capability to understand and intentionally use language about and for wellbeing across contexts — as its theoretical framework. Creative arts-based methods, including draw and tell …
Strategizing Success: Advancing Women's Leadership And Careers In Healthcare Through A Positive Gain Spiral, Farveh Farivar, Andrei A. Lux, Nasim Salehi
Strategizing Success: Advancing Women's Leadership And Careers In Healthcare Through A Positive Gain Spiral, Farveh Farivar, Andrei A. Lux, Nasim Salehi
Research outputs 2022 to 2026
Purpose – Women’s career progression in healthcare continues to lag men’s, particularly at senior leadership levels, limiting organizational performance and weakening leadership pipelines. This study applies Conservation of Resources (COR) theory’s positive gains cycle to examine how supportive organizational environments and human resource management practices can accelerate women’s advancement from early career stages to senior leadership. Design/methodology/approach – Using a social constructivist approach, we conducted 30 in-depth interviews with Australian healthcare leaders (20 female and 10 male) across multiple organizational levels. Thematic analysis identified the resources and interactions that enable sustained leadership progression for women. Findings – Four interconnected resources, …
A Mass Cytometry-Based Blood Cell Phenotyping Workflow Enabling Inclusion Of Resource-Limited And Rural Sites In Immune System Studies, Natalie J. Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen M. Mcguire
A Mass Cytometry-Based Blood Cell Phenotyping Workflow Enabling Inclusion Of Resource-Limited And Rural Sites In Immune System Studies, Natalie J. Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen M. Mcguire
Research outputs 2022 to 2026
Insight into disease detection and treatment through comprehensive immune phenotyping relies on the generation of high-quality data. However, the execution of robust immune monitoring in clinical trials by flow cytometry is complex due to logistical challenges in sample preparation and reagent stability. These challenges are exacerbated when considering remote and rural communities in Australia, which are burdened by both an increased prevalence and a worse prognosis of many chronic and infectious pathologies. This is not unique to the Australian context as globally remote and rural communities are underrepresented in biomedical research studies, contributing to persistent health inequities. To address these …
Association Between Protein Intake From Animal And Plant Sources And The Presence Of Frailty In Community-Dwelling Australian Women, Trent Bozanich, Jack Dalla Via, Simone Radavelli-Bagatini, Cassandra Smith, Elsa Dent, Anthony Villani, Robin M. Daly, Michael Tieland, Jonathan M. Hodgson, Kun Zhu, Richard L. Prince, Marc Sim
Association Between Protein Intake From Animal And Plant Sources And The Presence Of Frailty In Community-Dwelling Australian Women, Trent Bozanich, Jack Dalla Via, Simone Radavelli-Bagatini, Cassandra Smith, Elsa Dent, Anthony Villani, Robin M. Daly, Michael Tieland, Jonathan M. Hodgson, Kun Zhu, Richard L. Prince, Marc Sim
Research outputs 2022 to 2026
We investigated the cross-sectional association between total, animal and plant protein intake with the presence of a multidimensional measure of frailty in older women. Participants included 1380 community-dwelling Australian women, mean (SD) age 75.1 (2.7) years. A validated food frequency questionnaire was used to determine total, plant, and animal protein intake. Frailty was assessed using a frailty index across numerous health domains (scored 0–1, ≥0.25 indicating frailty). Cross-sectional associations were analysed using multivariable-adjusted logistic regression models. In total, 275 (19.9%) women were identified as frail. A non-linear inverse association was observed between higher intakes of total protein and the odds …
Does Performing Partial Repetitions Beyond Momentary Failure Enhance Muscle Hypertrophy In Volume-Load-Equated Calf-Raise Resistance Training?, Amirali Goli, Parsa Attarieh, João Pedro Nunes, Saman Nehegadar, Saaed Khani, Mohmad Fashi, Sajjad Ahmadizad
Does Performing Partial Repetitions Beyond Momentary Failure Enhance Muscle Hypertrophy In Volume-Load-Equated Calf-Raise Resistance Training?, Amirali Goli, Parsa Attarieh, João Pedro Nunes, Saman Nehegadar, Saaed Khani, Mohmad Fashi, Sajjad Ahmadizad
Research outputs 2022 to 2026
The aim of this study was to determine whether extending traditional calf-raise resistance training sets with partial-range-of-motion (ROM) repetitions in the more dorsiflexed ROM enhances muscular hypertrophy. Sixteen untrained men (25.0±1.7y) completed 10 weeks of unilateral standing calf-raise training (2×/wk) in a within-subject design: one leg performed traditional 10-14RM sets to full-ROM momentary failure (MF; 4-6 sets/session) and the other leg performed half as many sets to full-ROM failure followed by partial-ROM repetitions to a second failure in the more dorsiflexed ROM (PBF; 2-3 sets/session). Total volume-load was equated between conditions; repetitions were counted the same way regardless of the …
Effectiveness, Reach, Uptake, And Feasibility Of Digital Health Interventions For Culturally And Linguistically Diverse Populations Living With Prediabetes Across The Lifespan: Systematic Review And Meta-Analysis, Lisa Whitehead, Min Zhang, Wai Hang Kwok, Diana Arabiat, Amanda Towell Barnard
Effectiveness, Reach, Uptake, And Feasibility Of Digital Health Interventions For Culturally And Linguistically Diverse Populations Living With Prediabetes Across The Lifespan: Systematic Review And Meta-Analysis, Lisa Whitehead, Min Zhang, Wai Hang Kwok, Diana Arabiat, Amanda Towell Barnard
Research outputs 2022 to 2026
Background: Culturally and linguistically diverse (CaLD) populations are at a higher risk of developing prediabetes; however, the effectiveness and implementation of digital health interventions for prediabetes management in this population are not well understood. Objective: This review aims to evaluate the effectiveness and implementation of digital health interventions (DHIs) versus usual care for glycemic control in CaLD populations living with prediabetes. Methods: This review aimed to include people of any age living with prediabetes who are from a CaLD background. Experimental and quasi-experimental studies that compare digital health interventions to usual care, waitlist, or active control were eligible. The primary …
Enhancing Physical Performance With Ischemic Preconditioning: A Systematic Review And Meta-Analysis Of Moderators And Performance Outcomes, Yilin Zhang, Kai Xu, Hao Kong, Mingyue Yin, Chenghao Liu, Yun Xie, Liam Kilduff, Gustavo R. Mota, Olivier Girard
Enhancing Physical Performance With Ischemic Preconditioning: A Systematic Review And Meta-Analysis Of Moderators And Performance Outcomes, Yilin Zhang, Kai Xu, Hao Kong, Mingyue Yin, Chenghao Liu, Yun Xie, Liam Kilduff, Gustavo R. Mota, Olivier Girard
Research outputs 2022 to 2026
This study examined the effects of ischemic preconditioning (IPC) on physical performance, considering the influence of timing, warm-up (WU), participant characteristics, and IPC protocols structure. A total of 90 trials (1,439 participants) were retrieved from three databases and assessed using PICOS criteria. Multilevel meta-analyses with cluster-robust variance adjustments were conducted to calculate pooled effect sizes (Hedge’s g). Risk of bias and certainty of evidence were assessed using the RoB 2 tool and GRADE framework. IPC produced a trivial but significant improvement in physical performance (g = 0.13, P < 0.01), which persisted after excluding SHAM effects (g = 0.10; P < 0.01). Significant improvements were observed for maximum repetitions, time to failure, and power output, but not for jump ability, strength, or oxygen uptake. Comparable benefits were found for anaerobic (g = 0.15) and aerobic (g = 0.10) exercise, with greater effects in males and less-trained participants. Performance was further enhanced when IPC was followed by WU (g = 0.16), with the optimal IPC-to-WU interval being ~42 minutes. Without WU, the effective IPC window narrowed to 6–7 minutes. In practice, IPC can enhance physical performance, independently of sham effects, moderated by sex, training level, and WU. For competition or testing, the most effective strategy appears to be 3 or 4 × 5-min IPC protocol, followed by a 42-min interval, standardized warm-up, and endurance testing. For mechanistic studies, WU should be excluded, and testing conducted 6-7 minutes post-IPC. Future research should target women, middle-aged individuals, and elite athletes.
Exploring Cultural Values In Alcohol And Other Drug Use Among African Australian Youth: A Qualitative Study, Abraham Kenin, Justine Dandy, Kwadwo Adusei-Asante, Sonam Pelden
Exploring Cultural Values In Alcohol And Other Drug Use Among African Australian Youth: A Qualitative Study, Abraham Kenin, Justine Dandy, Kwadwo Adusei-Asante, Sonam Pelden
Research outputs 2022 to 2026
The heritage cultural values of Sub-Sahara African (SSA) migrants in the Australian sociocultural context could offer insights into understanding the problem of Alcohol and Other Drug (AOD) use among SSA Australian youth. This study explored the conceptualization of SSA cultural values in Australia, and to establish how they relate to AOD use among SSA Australian youth. Utilizing convenience sampling, one-on-one interviews were conducted with a total of 18 SSA Australians. The participants comprised 9 youth (aged 18–30; 4 females, 5 males), and 9 community leaders (aged 35–74; 4 females, 5 males). Based on a reflexive thematic analysis of the data, …
Influence Of Isometric Hamstring Assessment Modality: Asymmetries Across Bilateral And Unilateral Testing Procedures, Adam E. Sundh, Nicholas J. Ripley, A. J. Lamb, Conor J. Cantwell, Paul Comfort
Influence Of Isometric Hamstring Assessment Modality: Asymmetries Across Bilateral And Unilateral Testing Procedures, Adam E. Sundh, Nicholas J. Ripley, A. J. Lamb, Conor J. Cantwell, Paul Comfort
Research outputs 2022 to 2026
Purpose: The aim of this study was to evaluate whether unilateral and bilateral assessments display comparable results during the isometric long-lever bridge and to examine the directionality of asymmetry fluctuations across testing occasions. Methods: Forty-four participants comprising of 30 men (age: 19.4 ± 1.3 years; height: 179.8 ± 6.3 cm; body mass: 80.4 ± 10.3 kg) and 14 women (age: 20.0 ± 1.3 years; height: 166.9 ± 7.2 cm; body mass: 64.4 ± 7.4 kg) volunteered to participate in the study. All participants completed two separate testing sessions consisting of two maximal bilateral and unilateral repetitions respectively of the isometric …
Nurse Practitioner Students' Perceptions Of An Artificial Intelligence Differential Diagnosis Tool: A Pilot Study, Nilufeur Mckay, Peter Palamara, Adam Mccavery, Kaoru Nosaka, Wai Hang Kwok
Nurse Practitioner Students' Perceptions Of An Artificial Intelligence Differential Diagnosis Tool: A Pilot Study, Nilufeur Mckay, Peter Palamara, Adam Mccavery, Kaoru Nosaka, Wai Hang Kwok
Research outputs 2022 to 2026
Aim: The aim of this study is to assess nurse practitioner students' perceptions and engagement with Isabel's artificial intelligence (AI) based differential diagnosis tool to support their decision-making skills during their theoretical and clinical placement training. Design: This pilot study used a cross-sectional design. Methods: Twenty-six nurse practitioner students provided feedback on their use of an AI differential diagnosis tool in both academic and clinical contexts. This survey used the Post-Study System Usability Questionnaire to assess the engagement levels and usability of the AI tool. Additional questions were included to evaluate the usage patterns, adequacy in training and confidence in …
One Of These Things Is Not Like The Others: Disentangling The Concepts Of Range Of Motion Versus Flexibility, And Flexibility Training Versus Stretching, José Afonso, Anthony J. Blazevich, David George Behm, Markus Tilp, Konstantin Warneke
One Of These Things Is Not Like The Others: Disentangling The Concepts Of Range Of Motion Versus Flexibility, And Flexibility Training Versus Stretching, José Afonso, Anthony J. Blazevich, David George Behm, Markus Tilp, Konstantin Warneke
Research outputs 2022 to 2026
In this Current Opinion, we revisit key terminological distinctions in sports sciences, emphasizing the implications of conflating related but distinct concepts, particularly range of motion (ROM) versus flexibility and flexibility training versus stretching. While often used interchangeably, these terms represent nuanced constructs with distinct physiological and practical implications. ROM encompasses both modifiable (e.g., soft tissue extensibility, neural control) and non-modifiable factors (e.g., bone structure), whereas flexibility is only one of several trainable components of ROM, largely referring to the extensibility of periarticular soft tissues. Misunderstanding these distinctions risks erroneous assessments and inappropriate exercise prescriptions. We also challenge the common practice …