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2026

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Hester’S Dubious Roots And Legacy: Open Fields Doctrine Under Scrutiny, Laura K. Donohue Jan 2026

Hester’S Dubious Roots And Legacy: Open Fields Doctrine Under Scrutiny, Laura K. Donohue

Georgetown Law Faculty Publications and Other Works

For over a century, open fields doctrine has shaped Fourth Amendment law, denying people the right to be secure on their own property. Its application has steadily expanded, with the result that, by some estimates, the Government can now engage in warrantless surveillance of some ninety-six percent of private land and buildings regardless of fences, postings, the distance from public roads or byways, or the use to which the property is put. An originalist approach throws the doctrine into disarray: at the time of the Founding, common law protected the curtilage, which extended to the fields, barns, storehouses, and other …


Low Burden Of Clinically Relevant Anaemia And Thrombocytopenia Among Adolescents Living With Hiv Receiving Tenofovir/Lamivudine Plus Dolutegravir: The Cipher-Adola Study In Cameroon, Nadine Nguendjoung Fainguem, Yagai Bouba, Rachel Kamgaing, Jeremiah Efakika Gabisa, Aude Christelle Ka’E, Michel Carlos Tommo Tchouaket, Alex Durand Nka, Cynthia Ayafor, Lum Forgwei, Upal Roy Jan 2026

Low Burden Of Clinically Relevant Anaemia And Thrombocytopenia Among Adolescents Living With Hiv Receiving Tenofovir/Lamivudine Plus Dolutegravir: The Cipher-Adola Study In Cameroon, Nadine Nguendjoung Fainguem, Yagai Bouba, Rachel Kamgaing, Jeremiah Efakika Gabisa, Aude Christelle Ka’E, Michel Carlos Tommo Tchouaket, Alex Durand Nka, Cynthia Ayafor, Lum Forgwei, Upal Roy

Health & Biomedical Sciences Faculty Publications

Background: Anaemia and thrombocytopenia adversely affect adolescent HIV outcomes, yet adolescent-specific data from the tenofovir/lamivudine/dolutegravir (TLD) era remain scarce, and access to full blood count (FBC) testing is limited in Cameroon. We evaluated the prevalence, severity, and factors associated with these cytopenias among adolescents living with HIV (ADLHIV) in the TLD era.

Methods: Multicentre cross-sectional study was conducted among ADLHIV (10-19 years) receiving TLD in the CIPHER-ADOLA cohort in Cameroon. Full blood count, viral load (VL) and CD4-count were performed. Factors associated with anaemia and thrombocytopenia were ascertained.

Results: A total of 252 ADLHIV was enrolled (50.8% male, 83.3% were …


Research Initiative For Northeast Grazing Soils (Rings) Soil Carbon Data Report, Karla M. Jarecke, Joseph P. Amsili, Alexandra Contosta, Caitlin Hicks Pries, Kelsey H. Jensen, Morgan Mcclure, Alexander Steiner, Eric Von Wettberg, Mojtaba Zeraatpisheh Jan 2026

Research Initiative For Northeast Grazing Soils (Rings) Soil Carbon Data Report, Karla M. Jarecke, Joseph P. Amsili, Alexandra Contosta, Caitlin Hicks Pries, Kelsey H. Jensen, Morgan Mcclure, Alexander Steiner, Eric Von Wettberg, Mojtaba Zeraatpisheh

Faculty Publications

The Research Initiative for Northeast Grazing Soils (RINGS) is a multi-institutional collaboration with a mission to advance the understanding of soil organic carbon (SOC) dynamics in grazing systems across the northeastern United States. RINGS distributed a survey between October 2025 and June 2026 to researchers and practitioners across the Northeast to identify where SOC data has been collected and the basic field and lab methods used. The survey asked participants to describe existing soil datasets collected on land directly or indirectly impacted by grazing livestock. The survey was distributed to colleagues of RINGS researchers that work at university, corporate and …


Amalie Joachim: Reminiscences Of Childhood, Robert W. Eshbach Jan 2026

Amalie Joachim: Reminiscences Of Childhood, Robert W. Eshbach

Faculty Publications

This bilingual edition presents Reminiscences of Childhood, the autobiographical narrative of the Austrian operatic singer Amalie Joachim (née Schneeweiss), in Nina Joachim’s English translation together with the original German text. Written for her daughters, the memoir recounts Joachim’s family background in Carinthia and Styria; her early musical training and exposure to domestic chamber music; the political and personal upheavals of the revolutions of 1848; the death of her father and the family’s subsequent poverty; and her first theatrical engagements in Troppau and Hermannstadt. The narrative offers a vivid first-person account of musical life, female artistic formation, family survival, provincial theatre, …


Workshop Outcomes Report: 2nd International Workshop On Seismic Resilience Of Arctic Infrastructure And Social Systems, Majid Ghayoomi, Daniela Morganti Jan 2026

Workshop Outcomes Report: 2nd International Workshop On Seismic Resilience Of Arctic Infrastructure And Social Systems, Majid Ghayoomi, Daniela Morganti

Faculty Publications

The report provides an overview of the second international workshop on Seismic Resilience of Arctic Infrastructure and Social Systems. The report discusses agenda, workshop activities, interdisciplinary working groups, and results. It ends with several strategic questions and investigation plans that were developed as part of the workshop activities.


Concordance Of Fluorescence In Situ Hybridization, Whole-Exome Sequencing, And Chromosomal Microarray For Evaluating High-Risk Molecular Features In Meningiomas, Brenndan Crumley, Emilie Russler-Germain, Sonika Dahiya Jan 2026

Concordance Of Fluorescence In Situ Hybridization, Whole-Exome Sequencing, And Chromosomal Microarray For Evaluating High-Risk Molecular Features In Meningiomas, Brenndan Crumley, Emilie Russler-Germain, Sonika Dahiya

2020-Current year OA Pubs

BACKGROUND: Meningiomas are the most common primary intracranial tumors, classified into three WHO grades based on histologic and/or molecular criteria. cIMPACT-NOW Update 8 underscores the increasing importance of molecular testing in grading and risk stratification, noting that morphologically WHO grade 1 tumors with concurrent 1p and 22q losses demonstrate clinical behavior comparable to WHO grade 2 meningiomas. This study aimed to assess the concordance of fluorescence in situ hybridization (FISH), chromosomal microarray analysis (CMA), and whole-exome sequencing (WES) in defining the molecular risk profile of meningiomas.

METHODS: A total of 113 meningiomas were analyzed by WHO grade to assess the …


School Library Professionals’ Perspectives On Current And Future Workforce Challenges, Margaret Kristin Merga, Saiyidi Mat Roni Jan 2026

School Library Professionals’ Perspectives On Current And Future Workforce Challenges, Margaret Kristin Merga, Saiyidi Mat Roni

Research outputs 2022 to 2026

While school library professionals work across many nations, supporting student learning and wellbeing, there is limited current research capturing shared issues faced by this educational workforce. The International School Library Workforce Survey collected insights from 971 respondents across 63 countries derived from analysis of both quantitative and qualitative data. Findings suggest that in an international context, school library professionals are experiencing notable issues that impact upon their morale and their ability to enact their professional roles. Respondents were more likely to disagree then agree that school library professionals were typically valued in their country. While the vast majority of respondents …


Co-Design Of An Online Mindfulness Program For Informal Carers Of People Living With Dementia: A Qualitative Study Of Co-Designers’ Experience, Charunya A.K.R. Abeysinghe Mudiyanselage, Seng Giap Marcus Ang, Aisling Smyth, Joanne M. Dickson, Beverley Ewens Jan 2026

Co-Design Of An Online Mindfulness Program For Informal Carers Of People Living With Dementia: A Qualitative Study Of Co-Designers’ Experience, Charunya A.K.R. Abeysinghe Mudiyanselage, Seng Giap Marcus Ang, Aisling Smyth, Joanne M. Dickson, Beverley Ewens

Research outputs 2022 to 2026

Introduction: Informal carers face significant challenges related to care provision for people living with dementia. Participating in a mindfulness-based stress reduction program could improve the wellbeing of informal carers. However, engaging in these programs can be difficult for informal carers due to the needs of their care recipients. Purpose: This study aimed to co-design an online mindfulness program in collaboration with a range of stakeholders and those with lived experience as carers. Methods: This co-design study adopted an interpretive descriptive qualitative approach to the development of the program. The stakeholders (co-designers) included people with lived experience as informal carers and …


Fall Prevention Interventions In Community-Dwelling Older People With Cognitive Impairment: A Systematic Review, Sumattana Glangkarn, Pelden Chejor, Rujira Nonsa-Ard, Kasama Wongprachum, Sirapat Khodseewong, Chaiwut Bourneow, Davina Porock Jan 2026

Fall Prevention Interventions In Community-Dwelling Older People With Cognitive Impairment: A Systematic Review, Sumattana Glangkarn, Pelden Chejor, Rujira Nonsa-Ard, Kasama Wongprachum, Sirapat Khodseewong, Chaiwut Bourneow, Davina Porock

Research outputs 2022 to 2026

Introduction: Falls are a major health concern for older adults, particularly those with cognitive impairment. Many factors contribute to the risk of falls, making it a complex issue to manage. Aim: This systematic review aimed to identify and describe the implementation strategies used for fall prevention in community-dwelling older people with cognitive impairment. Eligibility criteria: The review included studies on fall prevention interventions for community-dwelling adults aged > 50 years with cognitive impairment. Eligible studies were primary research, including experimental, quasi-experimental, qualitative, and mixed methods designs, with detailed implementation strategies. Systematic reviews, protocols, editorials, opinions, commentaries, and conference papers were excluded. …


Fracture Energy Of Ambient-Cured Fly Ash-Based Geopolymer Concrete, Alireza Mohyeddin, Trijon Karmokar, Mohammad Fardipour Jan 2026

Fracture Energy Of Ambient-Cured Fly Ash-Based Geopolymer Concrete, Alireza Mohyeddin, Trijon Karmokar, Mohammad Fardipour

Research outputs 2022 to 2026

Fracture energy is a key parameter in current prediction models for capacity of structural anchors. During broader research on behaviour of structural anchors in ambient-cured fly ash-based geopolymer concrete, it was realised that despite extensive literature on Ordinary Portland Cement (OPC) and other types of geopolymer concrete, there is a lack of literature on fracture energy of such geopolymer concretes. The purpose of the current research is to measure this property for this specific type of concrete using Wedge Splitting Test (WST) method. This method was selected due to its stable crack propagation and suitability for small-sized specimens. The influence …


National Consensus On The Capabilities That Inform The Role Of Advanced Practice Paramedics: A Delphi Study, Alessia Restiglian, Lorna Martin, David Long, Louise Reynolds, Tony Walker, Ben Meadley, Ashleigh Finn, Alan Batt, Alecka Miles, Tania Johnston, Brendan Shannon Jan 2026

National Consensus On The Capabilities That Inform The Role Of Advanced Practice Paramedics: A Delphi Study, Alessia Restiglian, Lorna Martin, David Long, Louise Reynolds, Tony Walker, Ben Meadley, Ashleigh Finn, Alan Batt, Alecka Miles, Tania Johnston, Brendan Shannon

Research outputs 2022 to 2026

Advanced Practice Paramedics (APPs) are highly skilled paramedics who operate in diverse clinical settings both within and outside traditional ambulance services. International evidence demonstrates that APPs enhance patient outcomes in areas such as critical and primary care. In Australia, the expansion of APP roles and responsibilities has gained momentum; however, no nationally recognised framework exists to define their expected capabilities. This gap leads to inconsistencies in education, practice and role clarity. A standardised capability framework is therefore vital to guide the development, implementation and integration of APP roles within the Australian healthcare system. The primary aim of this study was …


Research Publication Performance Of The Australian And New Zealand Nursing And Midwifery Professoriate, Lisa Mckenna, Fiona Bogossian, Simon Cooper, Tracy Levett-Jones, Philippa Seaton Jan 2026

Research Publication Performance Of The Australian And New Zealand Nursing And Midwifery Professoriate, Lisa Mckenna, Fiona Bogossian, Simon Cooper, Tracy Levett-Jones, Philippa Seaton

Research outputs 2022 to 2026

Aim: To analyse research publication performance of Australian and New Zealand professors and associate professors of nursing and midwifery, and compare with 2016 data. Methods: A search of university websites was conducted to identify all nursing and midwifery professoriate in Australia and New Zealand. Each individual was then searched in the Scopus database to identify individual total citations, h-index, number of publications, first author Field Weighted Citation Impact (FWCI) and overall FWCI. Comparisons with 2016 data were also undertaken. Results: A total of 304 academics were included, comprising 270 from Australia and 34 from New Zealand, and 169 full professors …


Rock On Technology: Perspectives Of People With Neurological Conditions On Robot-Assisted Lower Limb And Gait Neurorehabilitation, Rachel G. Buckingham, Saran Chamberlain, Amanda Timler, Matthew K. Bagg, Nikki E. Bakhtazad, Taya Hamilton, Patricia Martinet, Bianca Haagman, Stuart I. Hodgetts, Barbara Singer, Ann Maree Vallence, Jodie Marquez, Eric Gaitho, Emma Gee, Jessica Nolan Jan 2026

Rock On Technology: Perspectives Of People With Neurological Conditions On Robot-Assisted Lower Limb And Gait Neurorehabilitation, Rachel G. Buckingham, Saran Chamberlain, Amanda Timler, Matthew K. Bagg, Nikki E. Bakhtazad, Taya Hamilton, Patricia Martinet, Bianca Haagman, Stuart I. Hodgetts, Barbara Singer, Ann Maree Vallence, Jodie Marquez, Eric Gaitho, Emma Gee, Jessica Nolan

Research outputs 2022 to 2026

Purpose: Explore perspectives of people living with neurological conditions in Western Australia (WA) on robot-assisted lower limb neurorehabilitation (RALLR), and implementation requirements. Materials and methods: This co-designed, qualitative descriptive study included people living with neurological conditions. In-person semi-structured focus groups (FGs) were facilitated by a person with lived experience of stroke. FGs were recorded, data were transcribed, and thematically analysed using a reflexive approach. Results: Five FGs included 24 participants (54.2% women, median age 50 years). Of these, thirteen participants had RALLR experience. Primary neurological conditions represented among participants comprised spinal cord injury (n = 11), stroke (n = 3), …


Superior Effects Of High-Intensity Interval Eccentric Cycling Training On Neuromuscular Adaptations With Similar Aerobic Adaptations To Concentric Cycling, Marcin Lipski, Joanne Trezise, Chris R. Abbiss, Kazunori Nosaka Jan 2026

Superior Effects Of High-Intensity Interval Eccentric Cycling Training On Neuromuscular Adaptations With Similar Aerobic Adaptations To Concentric Cycling, Marcin Lipski, Joanne Trezise, Chris R. Abbiss, Kazunori Nosaka

Research outputs 2022 to 2026

Purpose: We compared the effects of high-intensity interval eccentric (EC) versus concentric cycling (CC) training on aerobic capacity, muscle function and morphology. Methods: Healthy men (19–56 y) performed EC (n = 9) or CC (n = 8) training twice a week for 8 weeks. The training progressed from 5 × 2-min intervals with 1-min rest to 7 × 2-min intervals with 30-s rest. EC and CC were matched for perceived effort, and progressed from 30 to 36% of concentric peak power output (PPO10s) for CC and from 45 to 70% PPO10s for EC. Changes in peak oxygen consumption (VO2peak), incremental …


Nation, Nature And Childhood In Five Curricula: Towards Earthly Education, Zsuzsa Millei, Katarzyna Gawlicz, Lucy Hopkins, Camilla Eline Andersen, Danielle Ekman Ladru Jan 2026

Nation, Nature And Childhood In Five Curricula: Towards Earthly Education, Zsuzsa Millei, Katarzyna Gawlicz, Lucy Hopkins, Camilla Eline Andersen, Danielle Ekman Ladru

Research outputs 2022 to 2026

This article explores the relations between nation, nature and childhood in five early childhood education curricula in the Nordic, post-socialist and settler-colonial states with the focus on the role education plays in the face of the climate crisis. The authors identify three interconnecting themes in which nation, nature and childhood are entangled in these curricula: 1) national nature as an object of learning; 2) nature and home/birth land and Country; and 3) stewardship for national nature. Exploring these themes from the perspective of alternative pedagogies developed to address the child–nature relations during the Anthropocene, the authors argue that these notions …


Persistence Of Contested Value Cocreation Practices, Kim Feddema, Kaisa Koskela-Huotari, Paul Harrigan Jan 2026

Persistence Of Contested Value Cocreation Practices, Kim Feddema, Kaisa Koskela-Huotari, Paul Harrigan

Research outputs 2022 to 2026

The climate crisis and other global challenges make it clear that not only are new value cocreation practices (VCPs) needed, but some current VCPs must be discontinued. Prior service literature assumes that VCPs can be disrupted by reforming the institutions that govern them. However, empirical observations show that VCPs may persist even when targeted by institutional work, and recent organizational research points to contested practices that continue to be enacted even when challenged or criticized. To understand this phenomenon in value cocreation, we conducted an embedded case study of exotic pet-keeping—a set of VCPs that continue despite intervention efforts. Our …


A Critical Review Of The Theory Of Planned Behaviour In Tourism Research, Kourosh Esfandiar, Arghavan Hadinejad Jan 2026

A Critical Review Of The Theory Of Planned Behaviour In Tourism Research, Kourosh Esfandiar, Arghavan Hadinejad

Research outputs 2022 to 2026

The Theory of Planned Behaviour (TPB) has received considerable attention across various academic disciplines and remains one of the most widely applied–yet increasingly critiqued–theoretical frameworks in tourism research. Despite its widespread use, there is a notable lack of critical reflection on its adequacy in capturing the complexity of tourist behaviour and a limited exploration of alternative theoretical pathways. This paper addresses this gap by critically evaluating the appropriateness and limitations of the TPB in tourism research. Special attention is given to the Theory of Reasoned Goal Pursuit (TRGP), a recent extension of the TPB, alongside complementary frameworks from parent disciplines …


Advancing Sustainable Tourism Behavioural Research: A Metacognitive Perspective, Arghavan Hadinejad, Kourosh Esfandiar, Liubov Skavronskaya Jan 2026

Advancing Sustainable Tourism Behavioural Research: A Metacognitive Perspective, Arghavan Hadinejad, Kourosh Esfandiar, Liubov Skavronskaya

Research outputs 2022 to 2026

The current scholarly inquiry on sustainable tourism behaviour research predominantly relies on cognitive behavioural approaches, particularly exemplified by the widespread application of the theory of planned behaviour among other theories. Given recent advancements in psychology underscoring the necessity to expand beyond conventional cognitive frameworks, the current research aims to integrate metacognitive perspectives in sustainable tourism behaviour scholarship. This perspective explores the reflective awareness and control individuals exert over their cognitive processes which can uncover nuanced factors shaping sustainable tourism behaviour that may be overlooked in traditional cognitive models. Using a critical review approach, this research proposes the adoption of alternative …


An Evaluation Of Programmatic Assessment Across Health Professions Education Using Contribution Analysis, Janica Jamieson, Claire Palermo, Margaret Hay, Rachel Bacon, Janna Lutze, Simone Gibson Jan 2026

An Evaluation Of Programmatic Assessment Across Health Professions Education Using Contribution Analysis, Janica Jamieson, Claire Palermo, Margaret Hay, Rachel Bacon, Janna Lutze, Simone Gibson

Research outputs 2022 to 2026

Programmatic assessment is gaining traction in health professions education. Despite this popularity, educators continue to grapple with complex contextual factors that impact implementation and outcome attainment. We used contribution analysis, a theory-informed evaluation method, to understand the mechanisms underpinning successful implementation. Applying the six steps of contribution analysis, we developed a postulated theory of change (ToC) and then conducted a qualitative study with programmatic assessment stakeholders (graduates n = 15, supervisors n = 32, faculty n = 19) from four Australian dietetic programs. These data were analysed using the Framework Analysis method and integrated with data derived from a literature …


Configurations Of Work Design: A Person-Centered Perspective Of Job Demands And Resources In The Healthcare Sector, Arian Kunzelmann, Mina Askovic, Vivien W. Forner, Nate Zettna, Anupama Jolly, Shanta Dey, Helena Nguyen, Anya Johnson, Sharon K. Parker Jan 2026

Configurations Of Work Design: A Person-Centered Perspective Of Job Demands And Resources In The Healthcare Sector, Arian Kunzelmann, Mina Askovic, Vivien W. Forner, Nate Zettna, Anupama Jolly, Shanta Dey, Helena Nguyen, Anya Johnson, Sharon K. Parker

Research outputs 2022 to 2026

Work design is fundamental Human Resource Management (HRM) responsibility, which is crucial for employee well-being. Current HRM research on work design largely relies on variable-centered approaches. We argue that a person-centered approach uncovers more complex interaction patterns that are often obscured and provides a more holistic view of work design. Additionally, work design research often neglects occupational specificity, focusing on universal work characteristics. While this is important for generalizability, it can miss important industry and occupational variations, such as in healthcare. In this research, we focus on both universal work characteristics (feedback, autonomy, and support) and a dominant occupation-specific work …


Developing Indicators For Measuring The Sustainability Of Hotels, Reem Mohamed Abdalla Eltoum, S. Mostafa Rasoolimanesh, Joaquim Dias Soeiro, Mohsen Marjani Jan 2026

Developing Indicators For Measuring The Sustainability Of Hotels, Reem Mohamed Abdalla Eltoum, S. Mostafa Rasoolimanesh, Joaquim Dias Soeiro, Mohsen Marjani

Research outputs 2022 to 2026

The aim of this study is to develop a comprehensive set of indicators for monitoring and measuring sustainability in the hotel industry in Malaysia. It gives special attention to the environmental, social, resiliene and economic dimensions. This study applies the Delphi method by interviewing three key stakeholder groups—hotel managers, academicians, and hotel staff—in two rounds, in order to assess and validate indicators identified from the literature. Findings reveal demonstrate a strong attention to indicators associated with environmental sustainability, especially those which relates to waste management, consumption of energy and water and recycling which amounts to 51% of participants view. Further, …


Barriers To Adherence To Standard Precautions Among Community Health Workers: A Scoping Review, Margaret D. Adejumo, Melanie Baker, Davina Porock Jan 2026

Barriers To Adherence To Standard Precautions Among Community Health Workers: A Scoping Review, Margaret D. Adejumo, Melanie Baker, Davina Porock

Research outputs 2022 to 2026

Aim: This review aims to map available evidence on the adherence level and barriers to standard precautions among home-based community health workers. Methods: A scoping review using the JBI protocol searched multiple databases (Medline, CINAHL, PsycINFO and Web of Science) as well as Google Scholar for published articles on standard precaution practices of community health workers during home visits. Search terms included “standard precautions”, “guideline adherence”, “community health” and “home care”. Two-stage screening (title/abstract and full-text) was conducted to select relevant articles. Results: Eight eligible studies yielded three major themes: home environment context, individual factors and organisational factors. Findings indicated …


Consumer Responses To Ethical And Privacy Concerns In Ai Chatbots: Evidence From Offensive Language, Gender Bias, And Digital Privacy, Jikhan Jeong Jan 2026

Consumer Responses To Ethical And Privacy Concerns In Ai Chatbots: Evidence From Offensive Language, Gender Bias, And Digital Privacy, Jikhan Jeong

Economics Faculty Research & Creative Works

Due to the rapid innovation of artificial intelligence (AI) and big data, AI chatbots have become increasingly influential computational social systems (CSS) in everyday life. However, the expansion of interactions between AI chatbots and consumers has raised significant ethical and privacy concerns. Using data from an online survey, this study empirically examines how consumer concerns about AI ethics and privacy influence their intention to use AI chatbots. These concerns are categorized into three types: 1) offensive language (generated by AI chatbots or users); 2) gender-biased language (from either source); and 3) digital privacy violations. The findings suggest that prior experience …


Common Data Set, Georgia Southern University Jan 2026

Common Data Set, Georgia Southern University

Georgia Southern Common Datasets

No abstract provided.


Immortalization And Characterization Of Schwann Cell Lines Derived From Nf1-Associated Cutaneous Neurofibromas, Hua Li, Angela Hirbe, Et Al. Jan 2026

Immortalization And Characterization Of Schwann Cell Lines Derived From Nf1-Associated Cutaneous Neurofibromas, Hua Li, Angela Hirbe, Et Al.

2020-Current year OA Pubs

Neurofibromatosis type 1 (NF1) is an autosomal dominant condition in which patients are heterozygous for a disruptive pathogenic variant in the NF1 gene. The most characteristic feature of the condition NF1 is the neurofibroma, a benign, multi-cellular tumor which initiates when a cell of the Schwann cell lineage gains a somatic pathogenic variant of the other NF1 allele. Neurofibromas developing at nerve termini in the skin are termed "cutaneous" neurofibromas (cNFs), while those developing within larger nerves are termed "plexiform." Most patients develop cNFs beginning in late childhood or early adulthood, continuing throughout life at variable rates. Some patients may …


Characterization Of The Spatiotemporal Representations Of Visual, Semantic, And Memorability Features In The Human Brain, Yue Wang, Peter Brunner, Jon T. Willie, Runnan Cao, Shuo Wang Jan 2026

Characterization Of The Spatiotemporal Representations Of Visual, Semantic, And Memorability Features In The Human Brain, Yue Wang, Peter Brunner, Jon T. Willie, Runnan Cao, Shuo Wang

2020-Current year OA Pubs

Object recognition requires integrated processing that extends beyond the visual cortex, incorporating semantic and memory-related processes. However, it remains unclear how different attributes, such as visual, semantic, and memorability features, are encoded and interact during perception. Here, we recorded intracranial electroencephalography from 5,143 channels while participants viewed natural object images. We systematically characterized the spatiotemporal patterns of neural encoding for visual, semantic, and memorability attributes and showed that memorability was encoded in a distributed manner, which can be dissociated from visual and semantic coding. While the ventral temporal cortex (VTC) was engaged in encoding all three attributes, the representations were …


Capacity And Site Readiness For Hypertension Control Program Implementation In Nigeria: A Nationwide Cross-Sectional Study, Innocent Ijezie Chukwuonye, Mark D. Huffman, Et Al. Jan 2026

Capacity And Site Readiness For Hypertension Control Program Implementation In Nigeria: A Nationwide Cross-Sectional Study, Innocent Ijezie Chukwuonye, Mark D. Huffman, Et Al.

2020-Current year OA Pubs

BACKGROUND: The aim of this study is to determine the capacity and readiness of Nigerian primary healthcare facilities to adopt a multi-level approach for the diagnosis, treatment, and control of hypertension.

METHODS: Using a multi-stage sampling technique, 5 states were selected for the nationwide study, and 10 Primary Healthcare Centres (PHCs) were selected from each of the participating states. The 50 PHCs were evaluated using the World Health Organization-modified Service Availability and Readiness Assessment, focusing on the diagnosis and treatment of hypertension in Nigeria. The indicator scores for general and cardiovascular service preparedness were computed using the proportion of PHCs …


Implementing The Lung Donor (Lundon) Acceptability Score In U.S. Donor Management And Transplant Decision-Making: A Multi-Aim, Mixed-Methods Protocol, Nikki E. Rossetti, Su-Hsin Chang, Yan Yan, Graham Jaensch-Frie, Charles R. Liu, Nahom Y. Seyoum, Meghna Katta, Arvind Kumar, Zhizhou Yang, Christian Oncken, Christy Hamilton, Kyle Stumbaugh, Brendan Heiden, Sarah Peskoe, Varun Puri, Et Al. Jan 2026

Implementing The Lung Donor (Lundon) Acceptability Score In U.S. Donor Management And Transplant Decision-Making: A Multi-Aim, Mixed-Methods Protocol, Nikki E. Rossetti, Su-Hsin Chang, Yan Yan, Graham Jaensch-Frie, Charles R. Liu, Nahom Y. Seyoum, Meghna Katta, Arvind Kumar, Zhizhou Yang, Christian Oncken, Christy Hamilton, Kyle Stumbaugh, Brendan Heiden, Sarah Peskoe, Varun Puri, Et Al.

2020-Current year OA Pubs

BACKGROUND: Despite advances in transplantation science, a persistent shortage of donor lungs continues to limit access to life-saving lung transplants. The Lung Donor (LUNDON) Acceptability Score is a validated tool that predicts donor lung utilization and post-transplant recipient outcomes, but integration into practice remains limited. This study will evaluate determinants of LUNDON score adoption, its impact on clinical decision-making, and develop tools to support its implementation.

METHODS: This is a multi-aim mixed-methods pre-implementation study that will be conducted across U.S. Organ Procurement Organizations (OPOs) and lung transplant centers. Aim 1 will identify barriers and facilitators of LUNDON score adoption through …


Chronic Oral Cannabidiol Delays Seizure Onset And Reduces Seizure Burden In A Mouse Model Of Cln2 Disease, Joshua T. Dearborn, Keigo Takahashi, Nicholas R. Rensing, Michael Wong, Jonathan D. Cooper, Mark S. Sands Jan 2026

Chronic Oral Cannabidiol Delays Seizure Onset And Reduces Seizure Burden In A Mouse Model Of Cln2 Disease, Joshua T. Dearborn, Keigo Takahashi, Nicholas R. Rensing, Michael Wong, Jonathan D. Cooper, Mark S. Sands

2020-Current year OA Pubs

A growing body of literature describes the anti-inflammatory, neuroprotective, and anti-epileptic properties of the cannabis sativa constituent cannabidiol, suggesting that it might play a useful role in the treatment of neurodegenerative diseases. Late infantile neuronal ceroid lipofuscinosis (CLN2 disease) is a rare pediatric neurodegenerative disorder resulting from an inherited dysfunction of the lysosome. CLN2 disease, and its representative animal models, display neuroimmune response, neuroinflammation, neurodegeneration, and epileptic seizures, and these symptoms are all touted as potential targets of cannabidiol therapeutic benefit. Here, we treated a valid model of CLN2 disease with long-term daily cannabidiol (300 mg/kg) from 1 month of …


Poor Brain Reserve Increases Mortality Risk In Glioblastoma, Sree Gongala, Pamela Lamontagne, Danial Marcus, Et Al. Jan 2026

Poor Brain Reserve Increases Mortality Risk In Glioblastoma, Sree Gongala, Pamela Lamontagne, Danial Marcus, Et Al.

2020-Current year OA Pubs

BACKGROUND: Brain reserve refers to the structural capacity of the brain and correlates with age and Karnofsky Performance Status (KPS). While age and KPS are known independent predictors of survival in glioblastoma patients, the role of brain reserve in influencing glioblastoma outcomes remains unexplored. This study investigates the relationship between baseline brain-reserve metrics and survival outcomes in isocitrate dehydrogenase 1-wildtype (IDH1-WT) glioblastoma.

METHODS: We analyzed 841 patients with IDH1-WT glioblastoma using clinical data and presurgical MR images sourced from 4 institutions. MRI-based tumor characteristics and quantitative brain-reserve metrics were assessed using the Cancer Imaging Phenomics Toolkit and the Computational Anatomy …