Digital Commons Network^™

Effects Of An Early-Onset Hfd On Hepatic Functioning In A 3xtg Model Of Ad, Matthias Hirst

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Approximately 1 billion people currently live with obesity. Driven by factors such as a high-fat diet (HFD), this pathology can have drastic effects throughout the body, with the liver in particular being a main target of its downstream consequences. Although it is capable of storing lipids, excess fat can conglomerate in the liver and contribute to various hepatic pathologies. A specific pattern of hepatic dysfunction seen in response to an HFD is increased acetylation of mitochondrial proteins. Further, expression and activity of insulin-degrading enzyme (IDE), involved in the degradation of Aβ, are altered in response to an HFD. Aβ …

Sustainable Nutrient Management Opportunities For Small Communities In The U.S. With Lagoon Wastewater Treatment Systems, Denis Sigei Ruto

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lagoon wastewater treatment systems are among the most widely used secondary treatment technologies serving small and rural communities in the United States due to their low capital and operating costs, minimal energy requirements, and operational simplicity. While effective for removal of organic matter and suspended solids, most lagoon systems were not designed to achieve advanced nutrient removal. As regulatory priorities increasingly emphasize control of total nitrogen and total phosphorus to protect receiving waters and public health, lagoon-dependent communities face growing compliance challenges. These challenges are exacerbated by aging infrastructure, limited technical capacity, financial constraints, and insufficient infrastructure data, highlighting the …

The Impacts Of Experiential Learning On Moral Development, Jacob Tyler Greenfield

Graduate Theses, Dissertations, and Problem Reports (ETD)

Burnout remains a widely studied phenomenon in the healthcare literature, with much of the focus placed on reactive mitigation strategies that lack meaningful engagement with moral development. Healthcare education programs rarely incorporate formal learning experiences that promote moral development as a means of addressing burnout symptoms. This qualitative single case study examined how health professions students describe the impact of experiential learning on their moral development. Participants engaged in adapted photovoice methods, focus groups, and interviews to reflect on how serving as a Project MUSHROOM student leader influenced their morality. Four themes emerged: 1) recognizing bias and the need to …

Gcn5l1-Mediated Lysine Acetylation Regulates Mitochondrial Dysfunction In The Aged Heart, Jackson Edmond Stewart

Graduate Theses, Dissertations, and Problem Reports (ETD)

For over a century, cardiovascular disease (CVD) has been and remains the leading cause of death globally. CVD risk and severity increase significantly with advanced age, and mitochondrial dysfunction has been implicated in the pathogenesis of aging. Furthermore, mitochondrial health is crucial for cardiac function, as one-third of total cardiomyocyte volume is occupied by mitochondria in order to meet the high energy demand of contractile and relaxational function. It is thus crucial that we understand the pathological mechanisms driving mitochondrial dysfunction in aging and how this contributes to age-associated cardiovascular disease. The current manuscript aims to fill this knowledge gap …

Self-Leadership And Perceptions Of Artificial Intelligence: A Single-Case Study, Patrik Garren

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this single-case qualitative project is to uncover how self-leadership’s behavioral and cognitive strategies influence perceptions of Artificial Intelligence (AI) and AI adoption. While existing literature acknowledges that there is an association between self-leadership, technology’s perceived usefulness and ease of use, as well as comfort with AI preparedness and its professional impact, there is limited research on how self-leadership shapes perceptions of AI and AI adoption in real-life contexts. To fill this gap in contemporary literature, this project analyzes qualitative semi-structured interviews with 25 healthcare professionals involved in the implementation of ‘AI Model 1’ at their mid-sized United …

Evaluation Of Finger-Tightening Torque Applied To Implant Healing Abutments By Dental Providers With Varying Experience And Physical Characteristics: An In-Vitro Study., Bayan Abuhalimeh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Evaluation of Finger-Tightening Torque Applied to Implant Healing Abutments by Dental Providers with Varying Experience and Physical Characteristics: An In-vitro Study

Bayan Abuhalimeh, D.D.S

Aim: The primary objective of this project is to measure the actual torque applied by dental providers when finger-tightening a healing abutment and assess the variability among individuals. A secondary objective is to analyze the correlation between applied torque and: provider experience level (residents, general dentist, specialist); gender; age; and, physical attributes (e.g., grip strength, hand size, and dominant hand used for tightening). The null hypothesis is that there is no difference in the mean finger-tightening …

Psychometric Assessment Of The Ambivalent Ageism Scale: Investigating Measurement Invariance And Stability Across Groups And Time, Carly Pullen

Graduate Theses, Dissertations, and Problem Reports (ETD)

The goal of the current study was to examine the psychometric properties of the Ambivalent Ageism Scale (Cary et al., 2017) and to provide an understanding of how ageist attitudes might change or remain the same in response to a cultural and societal event. Measurement invariance is the assessment of the psychometric equivalence of a construct (e.g., ageism) across groups or waves of measurement (Putnick & Bornstein, 2016). The first step in measurement invariance analyses is configural measurement invariance, which is the evaluation of the factor structure, with the goal of producing the same number of factors and the same …

Pbmc Transcriptome Analysis Following Lps Stimulation Reveals Distinct Inflammatory Strategies In Feed-Efficient And Inefficient Beef Cattle, Yarahy Leal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Improving feed efficiency is a primary objective in livestock production, serving as a major driver of profitability and sustainability in beef cattle operations as feed costs continue to rise. Residual feed intake (RFI) and residual average daily gain (RADG) are widely recognized indicators of feed efficiency and are commonly used as selection traits to reduce production costs and environmental impact. Previous research suggests a functional shift in transcriptional activity associated with immunity depending on efficiency phenotype, with evidence of greater immune system robustness in more efficient animals. This dissertation examines the molecular mechanisms linking feed efficiency and immune competence and …

Bringing Patriarchy To Looksmaxxing: Identification And Exploration Of Strategies To Restabilize The Patriarchy In The Looksmaxxing Community, Mackenzie Grace Freeman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research literature on looksmaxxing is subsumed under the incelosphere, which is acknowledged as a white and male supremacist space. Yet, researchers fail to attend critically to the structure of patriarchy, choosing instead to base their analyses within the mainstream hegemonic masculinity paradigm. Using a Bourdieusian framework, this project fills a gap in the literature by transcending the mainstream paradigm to explain how the looksmaxxing community uses the body as a site of crisis management in response to patriarchal backlash, with the ultimate goal of restabilizing the patriarchy. This project uses a community-led survey from a popular online looksmaxxing community. This …

The Bleeding Edge Of Misogyny: How Gender-Based Harassment And Infrastructural Neglect Shape Menstrual Distress, Mackenzie J. Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite growing attention to menstrual health, organizational research has largely overlooked how workplace conditions shape menstrual experiences. Dominant perspectives frame menstruation as an individual issue that negatively affects work, neglecting how features of the work environment – such as gender-based harassment and access to menstrual-related infrastructure – contribute to menstrual distress. Addressing this gap, this dissertation adopts a bidirectional perspective, examining how social and material workplace conditions shape menstrual distress, defined as the extent to which menstrual symptoms interfere with daily functioning. Drawing on the transactional model of stress and objectification theory, I hypothesized that gender-based harassment would predict menstrual …

Early Life Adversity And Reward Reactivity In Humans, Maria C. Potts

Graduate Theses, Dissertations, and Problem Reports (ETD)

Both animal and human research has identified early life adversity (ELA) as a prominent risk factor for substance use disorder (SUD). However, the underlying mechanisms linking ELA to SUD development remain unclear. Animal studies point to differences in reward responsiveness as the primary explanation; specifically, that ELA could lead to individual differences in the attribution of incentive salience to reward-predictive cues, or the “sign-tracking” behavioral phenotype. Sign-tracking has been linked to addiction-related behaviors in both animal and human studies, but no human studies have examined whether sign-tracking could partially explain the link between ELA and SUD. In fact, human studies …

The Effect Of Innovative Value Proposition On Buyer Reactions: The Moderating Roles Of Price Orientation And Perceived Risk, Chad Stuttz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Value propositions are essential to the success of personal selling in the Business-to-Business (B2B) context. While earlier studies have offered valuable insights into the roles of value propositions in driving B2B sales, they have often regarded value propositions as uniform. In this dissertation, I argue that value propositions vary in their levels of innovativeness. The dissertation introduces the concept of innovative value proposition (IVP) and proposes that IVP indicates greater future growth potential to buyers, leading to more favorable reactions such as responsiveness and willingness to engage than less innovative ones. Additionally, the dissertation explores the moderating effects of buyer …

Facial Aesthetics And The Esthetic Plane: Effects Of Modern Lip Trends, Allison Paige Fritz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: The objective of this study is to evaluate whether there is a difference in aesthetic preferences of lip position between dental professionals and the general public, which we will refer to throughout the paper as lay people. In addition, age and gender differences will be determined to evaluate whether there is a need to re-evaluate the accepted normative values for lips to Esthetic plane (E-plane).

Experimental Design and Methods: A cross sectional, observational study design was used. The study aim was to evaluate the perception and opinions regarding lip position and fullness of both lay people …

The Role Of Temperature And Carbon Source In Nutrient Acquisition For Peptidoglycan Synthesis In A Gfp-Expressing Borreliella Burgdorferi, Barrett-Anne Conner Briggs

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lyme disease is the most common vector-borne disease in the United States with an estimated yearly incidence rate of more than 300,000 cases. Borreliella burgdorferi, the etiological agent of Lyme disease, is transmitted by the bite of an infected Ixodes scapularis tick and can cause debilitating pathologies affecting numerous body systems. Symptoms include fever, fatigue, joint pain, and a characteristic bull’s eye rash (erythema migrans) at the site of the tick bite. The timely and appropriate use of antibiotics effectively treats early Lyme disease; however, uncomfortable side effects reduce treatment compliance. If left untreated, long-term complications can arise including facial …

Programs Of Support For Wardship Experienced Students: Exploring Program Directors' Expectations And Experiences Through A Bioecological Framework, Adalheid Faith Crum

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this research is to explore the expectations and experiences of program directors of campus support programs which center wardship experienced students. This research question guided the current study: What expectations and experiences influenced program directors’ development and reform of a wardship-centered campus support program? This inquiry applies Ürie Bronfenbrenner’s Person–Process–Context–Time (PPCT) bioecological model. Semi-structured interviewing was utilized for this case study. In this research, six directors of campus support programs centering wardship experienced students were interviewed. Additionally, this work employs content analysis of twenty-eight National Research Collaborative for Foster Alumni and Higher Education (NRC-FAHE) publications, introducing fourteen …

Bridging The Gap: An Innovative Life Skills And Job Readiness Initiative For Those Facing And/Or Experiencing Homelessness, Alyssa Rae Lester

Graduate Theses, Dissertations, and Problem Reports (ETD)

Homelessness disrupts occupational functioning across all domains of daily life, yet individuals in transitional housing frequently lack access to structured life skills programming tailored to their current level of functioning. This doctoral capstone project developed, implemented, and evaluated a life skills and job-readiness curriculum at the West Virginia Coalition to End Homelessness West Run transitional housing facility in Morgantown, West Virginia. Grounded in Bronfenbrenner's Ecological Model of Human Development and the Bridging the Transition from Homeless to Housed framework, the curriculum addressed four domains: personal development, household management, financial literacy, and vocational readiness. A mixed-methods design combined a structured staff …

Strategic Transition Planning And Post-Graduation Preparedness For Students In Secondary School, Kelsey Renae Armentrout

Graduate Theses, Dissertations, and Problem Reports (ETD)

The transition period between high school and post-graduation life can be a challenging time for many students. Young adults may follow different paths, including going into the workforce or attending post-secondary education, as well as learning how to navigate life skills such as paying bills, buying a house or a car, applying for jobs, obtaining insurance, and occupations within the adult life stage. While young adults may learn about these things throughout their high school career, it is likely that the feelings of unpreparedness are continuously relevant. The purpose of this DCE is to develop and implement learning modules for …

The Dual-Factor Model (Dfm) Of Mental Among Appalachian Youth, Mawyah Adel Bashatah

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background. Adolescent mental health is a critical public health concern, particularly in rural Appalachian communities where rates of depression, anxiety, and substance use exceed national averages and access to mental health resources remain severely limited. Traditional mental health frameworks rely predominantly on the identification and reduction of psychopathological symptoms, neglecting the independent contributions of positive well-being to adolescent risk and resilience. The Dual-Factor Model (DFM) of mental health offers a more comprehensive alternative by simultaneously assessing subjective well-being (SWB) and psychopathology, classifying individuals into four distinct groups: Complete mental health, Vulnerable, Symptomatic but content, and Troubled. Despite the DFM’s growing …

“Black Students Matter”: A Phenomenological Study Of Black Student Experiences At A Predominately White Institution In Appalachia During The Dual Pandemic Of Covid-19 And Systemic Anti-Black Racism, Toni Owens

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the spread of COVID-19 escalated into a global pandemic in 2020, simultaneously, the nationwide media in the United States (U.S.) highlighted coverage of the country’s ongoing incidents of longstanding systemic anti-Black racism in America, another pandemic. In the Summer of 2020, a collective of Black students at West Virginia University (WVU) signed and publicly submitted a petition to the university’s leadership with a list of demands to address their needs as they were further exacerbated by the dual pandemic. This study is guided by the question, “What are the lived experiences of Black Students at West Virginia University during …

Interpersonal Dark Side Of Impostor Thoughts: Predicting Workplace Ostracism Via Surface Acting And Cognitive Dissonance, And The Moderating Role Of Self-Leadership, Asiye Zeytonli

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation investigates the "interpersonal dark side" of workplace impostor thoughts

(WIT), exploring how the internal experience of feeling like a professional fraud translates into

the social exclusion of colleagues through defensive ostracism. While prior literature has

extensively documented the intrapersonal distress associated with the impostor phenomenon,

such as anxiety and burnout this research addresses a critical gap by examining how these

internal states drive behaviors that harm the organizational social fabric. Drawing upon an

integration of Conservation of Resources (COR) theory and Cognitive Dissonance Theory

(CDT), I propose and test a dual-pathway model. The first pathway (COR) suggests that …

Formation-Based Analysis In Contemporary Saxophone Practice: A Case Study Of Ziwei Shi's The Blue Lotus Bloms, Jiageng Ren

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation examines contemporary saxophone repertoire through a formation-based analytical approach, using Ziwei Shi’s The Blue Lotus Blooms as a case study. It is organized into three parts. Part I establishes the conceptual and methodological framework by introducing the concept of “formation-based analysis,” positioning the “condition of musical formation” as its core. Further situating the study within scholarship on practice-based research, cross-cultural theory, and modernism/postmodernism. Part II provides a detailed analytical and performance-based investigation of the work, including the collaborative commissioning process, the application of Thaat as a pitch resource, the role of extended techniques and embodied endurance, and contrasting …

The Impact Of Caregiver Training And Education On Confidence And Perceived Competence In Facilitating Self-Care Skills In Children, Ryan M. Coen

Graduate Theses, Dissertations, and Problem Reports (ETD)

Caregivers, especially those residing in rural Appalachia, face significant barriers and hardships that can hinder their ability to promote ADL, IADL, and self-care skill development. These barriers faced include geographic isolation, socioeconomic barriers, and a high prevalence of disabilities. Many caregivers may struggle to facilitate these self-care skills competently and effectively, and a gap is present in the most effective means to teach caregivers in this region the necessary skills. With almost 20% of individuals in West Virginia lacking access to reliable internet and physical isolation, many of these educational materials may not be effectively distributed (West Virginia Department of …

Bridging The Sensory Gap With Occupational Therapy: Program Development For Sensory Integration In Inpatient Rehabilitation For Adults With Central Nervous System Injuries, Callie Marie Honaker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: This project aimed to identify sensory processing deficits in adults with central nervous system injuries and to inform the development of sensory-informed program components in an inpatient rehabilitation setting. Participants: A total of 76 adults admitted with diagnoses including cerebrovascular accident, brain injury, and spinal cord injury were included. Methods: A structured sensory screening and mental health questionnaire were administered and compared to prescreening admission documentation and PHQ-9 scores. Descriptive statistics and inferential analyses were conducted. Results: Sensory impairments were highly prevalent, with participants demonstrating an average of three impairments across the sensory domains. Proprioceptive, tactile, and visual deficits …

Lighting The Woods When There Are No Woods, Michael M. Mcginley

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Lighting and Into the Woods

Michael M. McGinley

This thesis will document my own journey into the woods. I will discuss my role as the lighting designer, highlighting my design processes and decisions. The show’s evolution and history from the first design meeting to opening night will be documented and reflected upon. Additionally, I will expand on collaboration with the other design team members, the challenges and struggles that I encountered, and lastly my own reflection on the entire process. I will be using lighting paperwork, research photos, and production photos to illustrate key points and highlight details.

Operationalizations Of Adverse Childhood Experiences And Health Prediction, Sarah Josephine Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

Exposure to adverse childhood experiences (ACEs) has been consistently linked to suboptimal health outcomes and behaviors across the lifespan. As such, there has been widespread adoption of measures like the 10-item cumulative ACEs count measure developed by Felitti and colleagues (1998) across research literature and clinical practice. However, this measure was not developed with consideration of optimal psychometric properties and thus consists of several limitations that inhibit understanding of the specific dimensions of adversity that influence health outcomes. This 3-study dissertation focused on different measurement and statistical techniques to better understand the associations between ACEs and health. In study 1, …

Taxpayers Willingness To Use Ai Conversational Tools, Nessrine Mesto-Assaad

Graduate Theses, Dissertations, and Problem Reports (ETD)

With the rapid emergence of Artificial Intelligence Conversational Tools (AICTs), such as ChatGPT and Google Gemini, and their widespread use, the need to understand users’ acceptance of this emerging technology has increased. Prior research has investigated users’ acceptance of AICTs in hospitality, tourism, e-commerce, and retail industries. However, users’ acceptance of the use of AICTs for tax information remains relatively underexplored in the tax context. Therefore, this study investigates taxpayers’ willingness to accept and use AICTs for tax-related questions when e-filing their tax returns. Drawing on the Artificial Intelligence Device Use and Acceptance (AIDUA) model as a research framework, this …

Assessment Of Countermovement Jump In Athlete Status And Monitoring, Michael David Delong

Graduate Theses, Dissertations, and Problem Reports (ETD)

Utilizing a CMJ to test athlete physical abilities and training program efficacy is popular, as it is simple, noninvasive, and has significant relations with sport qualities. However, assessments often use discrete outcome measures. This research explored strategy-based measures accounting for eccentric power and time and may explain athlete status more effectively. The research objectives are to analyze the use of the mean power rate of the CMJ to compare athletes' playing ability and its usefulness in monitoring during off-season training. Additionally, power-time curve analysis added location and timing of effects due to fatigue or fitness adaptation. Proper testing and monitoring …

Essays On Stock Market Expectations And Financial Decisions, Shanxiang Yang

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation consists of three essays on stock market expectations and financial decisions. The first essay shows significant racial differences in expectations regarding future stock market performance. Using data from the Federal Reserve Bank of New York’s Survey of Consumer Expectations from 2013 to 2022, we find that, relative to White Americans, Black and Hispanic Americans have lower probabilistic expectations that the stock market will increase. This racial gap in expectations was even larger during the recession caused by the Covid-19 epidemic, suggesting that economic uncertainty exacerbates this heterogeneity in expectations. Furthermore, we show that relative to White Americans, the …

A Constraint-Based Approach To Developing Melodic Improvisational Skills In Intermediate Jazz Piano Students, Alton Xian Rong Wong

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the pedagogical value of a constraint-based approach in helping students develop improvisational fluency and coherence by facilitating audiation. Although there are pedagogical texts on jazz improvisation that incorporate exercises shaped by constraint-based thinking, there is neither a systematic framework for their application with students of varying levels and musical backgrounds, nor a clear explanation of their pedagogical purpose. This research investigates how constraint-based pedagogy, through the lens of rhythmic, harmonic, and melodic parameters, can be applied independently or collectively to support the development of improvisational fluency in intermediate level jazz piano improvisers. It argues that musical constraints …

Be A Man: Hypermasculinity And Hostile Attribution Bias As Predictors Of Violence, Kaley Nicole Potter

Graduate Theses, Dissertations, and Problem Reports (ETD)

In recent years, violence has risen to record-high numbers in communities and correctional facilities, with men perpetrating the vast majority of violent crimes. Hypermasculine values (e.g., power, aggression, and domination) have been linked to aggressive and violent behavior. Hostile attribution bias, which leads individuals to attribute hostile intent to neutral or ambiguous stimuli, has also been linked to aggression.

The current study used structural equation modeling (SEM) to examine hypermasculinity and hostile attribution bias as predictors of proclivity for violence, comprised of aggression and historical violence. The model was iteratively modified to assess changes in model fit and constructs. Male …