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2026

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Establishment Of An In Vitro Dss-Induced Epithelial Injury Model To Investigate Il-6 Signaling And Microbial Metabolite Mediated Barrier Recovery, Srijal Kunwar Jan 2026

Establishment Of An In Vitro Dss-Induced Epithelial Injury Model To Investigate Il-6 Signaling And Microbial Metabolite Mediated Barrier Recovery, Srijal Kunwar

Graduate Studies Theses and Dissertations 2026

Dextran sodium sulphate (DSS) is widely used in vivo to induce epithelial injury; however, the molecular effects of DSS on intestinal epithelial cells, that investigate inflammatory and metabolic repair mechanisms remain unclear. Here, we establish an in vitro DSS-induced epithelial damage model using differentiated Caco-2 cell monolayer. Exposure to 2.5%(w/v) DSS for 24 hours resulted in significant upregulation of pore forming protein Claudin-2(2.677-fold) and oxidative marker, NOX-1(1.866-fold), accompanied by increased ROS production confirmed via DHE staining. Increased epithelial permeability was observed by TEER analysis, without significant cytotoxicity. Surprisingly, ELISA analysis revealed significant downregulation of IL-6 (p-value …


Modeling And Mitigating Atmospheric Degradation In Computer Vision With Application In Renewable Energy Prediction, Sumit Laha Jan 2026

Modeling And Mitigating Atmospheric Degradation In Computer Vision With Application In Renewable Energy Prediction, Sumit Laha

Graduate Studies Theses and Dissertations 2026

Weather-induced variability poses significant challenges to the reliability and performance of modern computational systems, particularly those relying on visual perception and environmental prediction. This dissertation focuses on enhancing computer vision and machine learning based predictive models that operate under varying atmospheric conditions. Two representative weather-impacted applications are investigated: image dehazing and solar photovoltaic (PV) power output forecasting. Image dehazing focuses on the restoration of clear, unobstructed visuals from hazy or foggy images, a task that is vital for various applications. On the other hand, photovoltaic (PV) power forecasting aims to predict future solar energy generation based on historical sky images …


Adapting Dramaturgical Pedagogy Into A Practical Framework For Young Dramaturgs, Kirby Lee Jan 2026

Adapting Dramaturgical Pedagogy Into A Practical Framework For Young Dramaturgs, Kirby Lee

Graduate Studies Theses and Dissertations 2026

Dramaturgy, while more established as practice in professional theatre, remains inconsistently applied and often underutilized in university theatre contexts. Despite its historical significance and continued evolution, some theatre companies and many academic institutions still struggle to clearly define or effectively integrate the dramaturg’s role. This thesis hopes to create a framework for novice dramaturgs by examining the origins and development of dramaturgy, analyzing its shifting functions in contemporary theatre, offering my own dramaturgical experiences through the lens of three quite different plays and finally, establishing basic principles of the discipline. Beyond its historical and professional contexts, this study investigates the …


Internalized Shame, Self-Focused Attention, And Post-Event Processing In Everyday Social Anxiety, Wooje Lee Jan 2026

Internalized Shame, Self-Focused Attention, And Post-Event Processing In Everyday Social Anxiety, Wooje Lee

Graduate Studies Theses and Dissertations 2026

The purpose of this study was to investigate how emotional processes, represented by internalized shame and daily shame (from the emotion-focused therapy model), and cognitive processes, represented by self-focused attention and post-event processing (from cognitive-behavioral models), operate on a daily basis to contribute to social anxiety. Data collected from a sample of 39 individuals with high social anxiety via an online survey and daily diaries was analyzed using multilevel path analysis. The results showed that, at the within-person level, daily shame experienced during an important social interaction influenced self-focused attention during that same interaction and subsequent post-event processing, which in …


Contextual Influences On Algebra 1 Achievement In Florida: A Multilevel Analysis Of Fsa Data And Policy Implications For B.E.S.T., Alberto Leiro Jr Jan 2026

Contextual Influences On Algebra 1 Achievement In Florida: A Multilevel Analysis Of Fsa Data And Policy Implications For B.E.S.T., Alberto Leiro Jr

Graduate Studies Theses and Dissertations 2026

This study examined how school-level and district-level contextual factors are associated with Algebra 1 achievement in Florida using a multilevel modeling framework. Drawing on statewide publicly available data from the Florida Standards Assessments (FSA), the analysis included schools nested within districts to account for the hierarchical structure of educational data. School-level predictors included absenteeism, economic disadvantage, English language learner status, student mobility, and the proportion of students with disabilities, while district-level variables included poverty and crime rates. Results from the null model indicated that a meaningful proportion of variance in Algebra 1 achievement was attributable to differences among districts, supporting …


High School Teachers' Perceptions And Experiences Of Legislative Changes: An Interpretative Phenomenological Analysis, Marie Lewis Jan 2026

High School Teachers' Perceptions And Experiences Of Legislative Changes: An Interpretative Phenomenological Analysis, Marie Lewis

Graduate Studies Theses and Dissertations 2026

The purpose of this interpretative phenomenological analysis was to explore the perceptions and experiences of high school English Language Arts teachers in one public school district in the state of Florida as they navigated educational legislation that has been implemented over the last five years. The study interviewed ten experienced high school ELA teachers who had taught for more than five years in Florida’s public school system. One semi-structured interview was conducted along with brief follow-ups to share thematic statements with the participants. This study also included a document analysis of HB 1467 and HB 1069 as well as the …


The Perceptions Of Instructional Coaching On Teacher Efficacy And Retention In Elementary Schools, Stephanie Lucas Jan 2026

The Perceptions Of Instructional Coaching On Teacher Efficacy And Retention In Elementary Schools, Stephanie Lucas

Graduate Studies Theses and Dissertations 2026

Administrators in a large school district in Central Florida encountered challenges regarding teacher retention and sustainability. Flite STEM coaching, a new instructional coaching model, was developed to support teachers in hopes of reducing those challenges. This model includes coaching cycles that encouraged collaboration and reflective thinking aligned with professional learning. This qualitative study focused on implementing the Flite STEM coaching model with teachers and instructional coaches. The coaching cycle consisted of the following: 1) a pre-observation conference, 2) video observation, 3) post-observation conference with feedback, and 4) a professional learning opportunity. It included DebriefScape Observation Dashboard resources to collect and …


Hunter. Hunted. Human: Warfighters' Emotional Responses To Weapons In Tactical & Strategic Context, Simon Mace Jan 2026

Hunter. Hunted. Human: Warfighters' Emotional Responses To Weapons In Tactical & Strategic Context, Simon Mace

Graduate Studies Theses and Dissertations 2026

Human emotional responses to weapons have long been assumed to be relatively parsimonious, comprised predominately of aggression, anxiety, and fear responses. However, most research on this weapons effect has focused on civilians – who are notably more likely to be targeted by than to employ weapons. So, there is reason to speculate that emotional responses to weapons vary more than previously believed. This is significant for three reasons. First, positive emotional responses generate more desirable combat behaviors, specifically the willingness to engage adversaries. Second, negative emotional responses catalyze an unpredictable range of behaviors, many of which are tactically and operationally …


The Diversity Of Flavivirus Antibody Dependent Enhancement (Ade) Profiles From A Pediatric Cohort In Mexico, Maiesha Samiha Mahmood Jan 2026

The Diversity Of Flavivirus Antibody Dependent Enhancement (Ade) Profiles From A Pediatric Cohort In Mexico, Maiesha Samiha Mahmood

Graduate Studies Theses and Dissertations 2026

The Aedes mosquito-borne flaviviruses Zika (ZIKV) and dengue (DENV-1-4) cause an estimated 400 million annual infections globally and pose an increasing threat to public health. Typically, individuals infected with ZIKV or a DENV serotype generate neutralizing serotype-specific antibodies and non-neutralizing, cross-reactive antibodies that bind multiple flaviviruses. Upon secondary heterotypic infection, pre-existing antibodies can either protect or exacerbate disease through antibody dependent enhancement (ADE). ADE occurs when non- or sub-neutralizing concentrations of cross-reactive antibodies facilitate viral uptake into FcγR-bearing myeloid cells, enabling infection of otherwise non-permissive cells and driving severe disease. To date, ADE has not been characterized at a population …


Generating Boundary Conditions For Compound Flood Modeling In A Probabilistic Framework, Pravin Maduwantha Mahanthe Gamage Jan 2026

Generating Boundary Conditions For Compound Flood Modeling In A Probabilistic Framework, Pravin Maduwantha Mahanthe Gamage

Graduate Studies Theses and Dissertations 2026

Flooding in coastal riverine environments is often driven by the combined influence of multiple hydrometeorological flood drivers, including storm surge, rainfall, waves, and river discharge, which is referred to as compound flooding. A robust flood hazard assessment requires simulation of a wide range of flood driver conditions through dynamic compound flood models to capture the variability in resultant flooding. However, such assessments remain limited by the short length of observational records and the high computational cost of physics-based methods used to generate temporally varying boundary conditions. This dissertation develops a statistical framework to characterize compound flood drivers and generate large …


The Amanah Project: A Pilot Educational Intervention Addressing Intimate Partner Violence In Muslim Communities In The United States, Tamara Makki Jan 2026

The Amanah Project: A Pilot Educational Intervention Addressing Intimate Partner Violence In Muslim Communities In The United States, Tamara Makki

Graduate Studies Theses and Dissertations 2026

This study is a two-part manuscript dissertation that addresses the need for culturally and faith-based responsive interventions for intimate partner violence (IPV) within the Muslim community in the United States (U.S). The first manuscript is a conceptual and literature-based paper that examines IPV within the Muslim community in the U.S. and explores the intersection of religion, culture, patriarchy, and systemic barriers influencing survivors’ help-seeking experiences. Particular attention is given to issues of accessibility, including the limited availability of culturally and religiously responsive IPV services for Muslim survivors. This manuscript argues for the development of culturally responsive, faith-integrated approaches that improve …


Appraising The Uniform: Stress, Predisposition, And Trust In Police Among Latin American And U.S. Latino Populations, Maren J. Mainx Jan 2026

Appraising The Uniform: Stress, Predisposition, And Trust In Police Among Latin American And U.S. Latino Populations, Maren J. Mainx

Graduate Studies Theses and Dissertations 2026

Public trust in police is central to regime legitimacy, yet reforms intended to build trust produce inconsistent results, and communities facing comparable conditions can respond differently to similar policing. This dissertation accounts for that variation by examining how stress shapes citizens’ responses to police visual cues. It proposes a framework in which citizens interpret these cues through their general trust in police—trust that weighs more heavily under stress. This framework is examined through a multi-method design spanning the Americas. Study 1 merges AmericasBarometer data with the Global Police Militarization Dataset across nineteen countries (2010–2023) to examine how stress and national …


Performance Analysis Of Labyrinth And Hybrid Seals For Supercritical Co₂ Turbomachinery Applications, Ghanshyam Sarobar Mandal Jan 2026

Performance Analysis Of Labyrinth And Hybrid Seals For Supercritical Co₂ Turbomachinery Applications, Ghanshyam Sarobar Mandal

Graduate Studies Theses and Dissertations 2026

Leaks account for large losses in turbomachinery systems, which has led to research on sealing technologies. The work presented studies the effect of a hybrid seal combining conventional labyrinth geometry and honeycomb structure by simulating supercritical carbon dioxide (sCO₂) flow through this geometry. The CFD solver compares effects such as changes in mass flow rate, formation of vortices, pressure profile, and seal performance as geometry angles of labyrinth teeth and honeycomb walls change at conditions normally found at higher pressures in these seals. Honeycomb walls were placed on the stator, ranging from 125°< θc< 55°. Labyrinth teeth were placed on the rotor at the same degrees. Honeycomb cell diameters were also varied, creating more resistance and turbulence within the flow. It was discovered that the honeycomb angle created stronger effects on vortices and boundary layer formation, while the labyrinth angle mainly affected the throttling of flow and loss generation. Combining all three angles created a relationship dictating the seal leakage. Dimensions of seals were based on gas turbine seals with changes to meet sCO₂ conditions. ANSYS was used to simulate static and rotating conditions until convergence on a specific geometry


Communication College Students And Their Career Readiness: An Evaluation From The Employer's Perspective, Carson Mann Jan 2026

Communication College Students And Their Career Readiness: An Evaluation From The Employer's Perspective, Carson Mann

Graduate Studies Theses and Dissertations 2026

Higher education institutions are seen as places that educate students in specific subjects and provide training that leads to either a career or further learning opportunities. Unfortunately, public trust in higher education has plummeted since 2015. The evolution of higher education has been the subject of speculation by various groups, but developing translational skills through effective internships could very well solve the issue at hand. Institutions ought to have data -driven evidence about their disciplines’ effectiveness and their translational ability to the workforce. To understand this, student career readiness must be evaluated. Students' career readiness is a vital measure of …


Genuine And Meaningful Black Character Narratives In Video Games, Derek L. Manns Jan 2026

Genuine And Meaningful Black Character Narratives In Video Games, Derek L. Manns

Graduate Studies Theses and Dissertations 2026

The lack of Black representation in video games reflects stereotypes and hollow narratives. Authentic and meaningful design of Black characters allows Black players a reflection of emotional attachments everyone wants when playing a game. Examining racial identities through avatars, critiquing the notion that customization equates to racial inclusivity, limited options and predominant, white-coded protagonists reinforce systemic biases in games (Dietrich, 2013). My Afrofuturistic content analysis framework explores Black culture with a future of speculative fiction. Reimagining the past, present, and future through Black narratives for alternate futures (Womack). Integrating these ideas enhance culture and aesthetics in this dissertation to highlight …


Development Of The Simultaneous Alcohol And Cannabis Use Expectancy Questionnaire (Sac-Eq), Shane D. Marohnic Jan 2026

Development Of The Simultaneous Alcohol And Cannabis Use Expectancy Questionnaire (Sac-Eq), Shane D. Marohnic

Graduate Studies Theses and Dissertations 2026

Background: Simultaneous alcohol and cannabis use (SAC/SAM), defined as using alcohol and cannabis at the same time so that their effects overlap, has been identified as a hazardous form of polysubstance use. Expectancies are a causal mechanism and can be changed with predictable reductions in substance use and associated consequences, yet only one measure has been developed to assess expectancies related to SAC. Due to limitations of the existing measure, this study sought to create a more comprehensive SAC expectancy scale. Method: Three phases of participants (Phase 1, N = 493; Phase 2, n = 4; Phase 3, n …


“I Am A Refugee Direct From Mississippi:” Drafting And Substitution As Muster Methods In Shaping Black Participation In The Union Army, 1863–1865, Carson R. Maschmeier Jan 2026

“I Am A Refugee Direct From Mississippi:” Drafting And Substitution As Muster Methods In Shaping Black Participation In The Union Army, 1863–1865, Carson R. Maschmeier

Graduate Studies Theses and Dissertations 2026

Historians have frequently emphasized voluntary enlistment as the primary means through which Black men entered military service, portraying military participation as an expression of autonomy and a pathway toward freedom and citizenship. Within this scholarship, few historians have examined how Black participation in the Union army as draftees and substitutes impacted Black men and their families. This thesis examines the role of drafting and substitution in shaping Black military participation in the Union Army during the American Civil War. By focusing on Pennsylvania's 8th United States Colored Troops (USCT), this study argues that drafting and substitution complicate the commonly accepted …


Experimental Demonstration Of A Laboratory Scale Packed Bed Reactor For Thermochemical Energy Storage Using Embedded Heating Elements, Zachary Monem Jan 2026

Experimental Demonstration Of A Laboratory Scale Packed Bed Reactor For Thermochemical Energy Storage Using Embedded Heating Elements, Zachary Monem

Graduate Studies Theses and Dissertations 2026

Thermochemical energy storage (TCES) is an emerging technology that is being studied as a carbon-neutral renewable alternative to conventional methods of large-scale power generation, such as the utilization of fossil fuels. TCES makes use of thermochemical materials to store and discharge energy in two-step reversible chemical reactions. Among the most promising TCES materials are metal oxides, which possess significantly higher energy storage densities compared to other TCES materials; consequently, thermochemical reactors are used to store and discharge large amounts of energy during reduction-oxidation cycles using metal oxide materials. The current work focuses on the design and experimental demonstration of a …


Comics In The Classroom: Social Science Teachers' Lived Experiences With Comic Art In Instruction, Robert W. Mcintosh Jan 2026

Comics In The Classroom: Social Science Teachers' Lived Experiences With Comic Art In Instruction, Robert W. Mcintosh

Graduate Studies Theses and Dissertations 2026

This qualitative descriptive phenomenological study explored secondary social science teachers’ lived experiences with comic art in classroom instruction. Existing research suggests that comic art, including comic books and graphic novels, can support student engagement, content understanding, visual literacy, and critical thinking; however, less is known about how teachers experience and make decisions about using comic art in social science education. Framed by Technological Pedagogical Content Knowledge and Social Cognitive Theory, the study treated comic art as a representational instructional technology and examined how teacher confidence and the context of their experience shaped its use. Data were collected through semi-structured interviews …


Towards An Understanding Of Learning In Immersive Virtual Reality: Investigating Learning Affordances To Bridge Theory And Practice, Gregory Mcgowin Jan 2026

Towards An Understanding Of Learning In Immersive Virtual Reality: Investigating Learning Affordances To Bridge Theory And Practice, Gregory Mcgowin

Graduate Studies Theses and Dissertations 2026

This dissertation examines how modality-specific scaffolding shapes performance, presence, and transfer in immersive virtual reality (I-VR). Framed through theories of extended cognition, real-time guidance is conceptualized as cognitive scaffolding that structures perception and action by embedding task-relevant information within the environment. Situated within the learning sciences and informed by 4E cognition (embodied, embedded, enactive, extended), this work develops a framework for understanding how I-VR affordances relate to learning and performance.

The empirical study investigates how scaffolding modality (audio vs. visual) influences presence and performance in a VR racing simulation. Using a 3 × 2 × 2 mixed factorial design, 111 …


Show Me The Money: Candidate Attributes, Fundraising, And The Impact On Congressional Representation., Dhanya Nair Jan 2026

Show Me The Money: Candidate Attributes, Fundraising, And The Impact On Congressional Representation., Dhanya Nair

Graduate Studies Theses and Dissertations 2026

What explains women’s candidate emergence in congressional primaries? Does candidate education, experience, and background influence how voters donate to male and female candidates? Using an original dataset, I examine the circumstances under which women are more likely to enter a congressional primary.  This thesis accounts for the variation in candidate emergence across Congressional districts related to district partisanship, candidate quality and fundraising capacity.   The theory suggests that the persistent gap in representation is partly due to women self-selecting to run in districts that favor their candidacy.  Strategic entry serves as a buffer against perceived bias in fundraising and electability. Additionally, …


Experimental And Computational Characterization Of A Rotorcraft-Tiltrotor Model Using Morphing Wings For Whirl Flutter Instability, Darrell Nieves Lugo Jan 2026

Experimental And Computational Characterization Of A Rotorcraft-Tiltrotor Model Using Morphing Wings For Whirl Flutter Instability, Darrell Nieves Lugo

Graduate Studies Theses and Dissertations 2026

Tiltrotor rotorcraft configurations combine the capabilities of vertical and forward flight, offering a crucial and advantageous design for maximizing the operational flight envelope. This versatility enables broad adaptability across numerous designs and platforms, including unmanned aerial vehicles (UAVs), micro-air vehicles (MAVs), and vertical take-off and landing (VTOLs) aircraft. However, propeller-based aircraft are susceptible to an aeroelastic instability at high flight speeds known as whirl flutter. This instability phenomena is a crucial research task and problem to investigate, as with advances in manufacturing and vehicle designs, these can yield new rotorcraft formats capable of advancing the flight envelopes at higher cruise …


Hidden Gem, Fraught Liability, Or Visible Asset? The Museum Of Contemporary Art Jacksonville, Keidra D. Navaroli Jan 2026

Hidden Gem, Fraught Liability, Or Visible Asset? The Museum Of Contemporary Art Jacksonville, Keidra D. Navaroli

Graduate Studies Theses and Dissertations 2026

This dissertation utilizes a combination of archival research, qualitative interviews, and data-driven analyses to examine how the Museum of Contemporary Art (MOCA) Jacksonville came under the governance of the University of North Florida (UNF). Founded in 1924, MOCA became a cultural institute of UNF in 2009 during the Great Recession. Tracing MOCA’s reinventions and geospatial movements across Jacksonville, this study considers the ideologies that informed the museum’s development, the locations that defined its service to Northeast Florida, and the financial conditions that necessitated its eventual rescue by a public university. The museum’s challenges are reflective of larger tensions in the …


Two-Phase Transcritical Carbon Dioxide Flow At The Microscale For Thermal Management Applications, Soroush Niazi Jan 2026

Two-Phase Transcritical Carbon Dioxide Flow At The Microscale For Thermal Management Applications, Soroush Niazi

Graduate Studies Theses and Dissertations 2026

High-power electronic and power-conversion devices now generate heat fluxes that exceed what conventional air- and single-phase-liquid cooling can dissipate, motivating the search for more capable coolants and cooling mechanisms. Carbon dioxide is an attractive candidate for this role: it is inexpensive, non-toxic, and environmentally friendly, and near its critical point its thermophysical properties change rapidly, which raises the heat-transfer coefficient. In addition, a large pressure drop produces strong cooling through the Joule–Thomson effect and phase change, so that the throttling element itself becomes a source of cooling. This dissertation studies the throttling, phase change, and choking of high-pressure carbon dioxide …


Well, If You Put It That Way Three Studies On Contract Framing In Incomplete Contract Environments, Garrison L. Nuttall Jan 2026

Well, If You Put It That Way Three Studies On Contract Framing In Incomplete Contract Environments, Garrison L. Nuttall

Graduate Studies Theses and Dissertations 2026

This dissertation contains three studies examining contract framing, with implications for how organizations structure and frame performance-based compensation systems. Across all studies, I compare penalty contracts to bonus contracts with gain framing and bonus contracts with loss framing. My first study examines how managers prefer to frame performance-based compensation systems on average and identifies how the traits trust propensity, empathy, personal norm of reciprocity, loss aversion, Machiavellianism, and critical thinking disposition are associated with certain preferences. I find that mangers prefer bonus contracts to penalty contracts on average and that empathy is positively associated with this preference. My second study …


The Role Of Alcohol Expectancies In The Relationship Between Social Anxiety And Protective Behavioral Strategies Among College Students, Jordan Ortman Jan 2026

The Role Of Alcohol Expectancies In The Relationship Between Social Anxiety And Protective Behavioral Strategies Among College Students, Jordan Ortman

Graduate Studies Theses and Dissertations 2026

College students with elevated social anxiety are at heightened risk for alcohol-related consequences despite not consistently reporting greater alcohol use. One potential explanation for this pattern is lower engagement in protective behavioral strategies (PBS). Social alcohol expectancies are relevant to PBS use because students with elevated social anxiety often expect alcohol to reduce social discomfort or facilitate social interaction, and these beliefs may correspond with lower use of strategies that constrain the pace or amount of drinking. The present study examined whether positive and negative social alcohol expectancies were intermediate variables in associations between social anxiety and three PBS domains: …


“How Far Do These Roots Go Down”: An Exploration Of Latinx And Latina Fans On Representation In Disney's Encanto, Noemi Nunez Jan 2026

“How Far Do These Roots Go Down”: An Exploration Of Latinx And Latina Fans On Representation In Disney's Encanto, Noemi Nunez

Graduate Studies Theses and Dissertations 2026

In this dissertation, I examine how Latinx and Latina audiences engaged with and interpreted Disney’s 2021 Encanto, an animated film celebrated for its representation of Colombian and broader Latinx culture. While scholarship on Latinx representation in media has expanded, less attention has been given to how Latinx audiences themselves respond to narratives that are meant to represent them, particularly within fan studies. Focusing on both a broader Latinx fan community and first-generation Latinas in the United States, this project explores how audiences negotiate representation and recognition using Encanto as a media text that centered a Latinx story. Drawing from …


Multi-Scale Drivers Of Beetle Biodiversity In A Rapidly Urbanizing Region, Alessandra Pandolfi Jan 2026

Multi-Scale Drivers Of Beetle Biodiversity In A Rapidly Urbanizing Region, Alessandra Pandolfi

Graduate Studies Theses and Dissertations 2026

As cities continue to expand, designing urban landscapes that balance ecological resilience with biodiversity conservation has emerged as a pressing challenge. This dissertation examines urban ecosystems as complex and dynamic environments shaping plant and animal communities, with a particular focus on ground-dwelling beetles as ecologically significant indicators of environmental change. Conducted across the Orlando metropolitan area, one of the fastest-growing regions in the United States, this dissertation integrates experimental and observational approaches. Specifically, it aims to (1) test sustainable landscaping practices, (2) compare the ecological outcomes of conventional and alternative residential landscape designs, and (3) assess how gradients of urbanization …


The Biosynthesis Of The Natural Product N-Nitroglycine, Gabriel Padilla Jan 2026

The Biosynthesis Of The Natural Product N-Nitroglycine, Gabriel Padilla

Graduate Studies Theses and Dissertations 2026

N-Nitroglycine (NNG) is a nitramine [R(R′)N–NO2; R′=H or alkyl] natural product (NP) produced by certain actinomycetes, such as Streptomyces noursei. At the beginning of this project, the biosynthesis of this NP was unknown. The goal was to determine how NNG and its nitramine moiety are enzymatically formed. This could lead to the discovery of novel nitramine NPs with diverse applications as well as alternative/green synthesis of nitramine explosives. This work begins by examining diverse biochemical N–N bond formation strategies. Nitrogen cycle enzymes, nitration of NPs, kutzneride biosynthesis, the aspartate/nitrosuccinate superfamily, hydrazinoacetic acid (HAA) biosynthesis, and streptozocin biosynthesis are among the …


Cracking The Code Of Ai Autonomy: Examining The Role Of Challenge And Hindrance Appraisals And Ai Literacy In Task Satisfaction, Rujuta Parekar Jan 2026

Cracking The Code Of Ai Autonomy: Examining The Role Of Challenge And Hindrance Appraisals And Ai Literacy In Task Satisfaction, Rujuta Parekar

Graduate Studies Theses and Dissertations 2026

AI is constantly evolving and being rapidly integrated into the workplace. Limited research has examined how this integration is affecting employee outcomes, and particularly the impacts of whether employees are expected or mandated to use AI for their work. The present study utilized the challenge-hindrance framework to examine the effect of autonomy in using AI on task satisfaction through challenge and hindrance appraisal among working adults. Since the ability to understand and use AI can influence how individuals perceive it, the moderating effect of AI literacy on the hypothesized research model is also examined. A multi-wave research design was used …