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2026

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Understanding The Support And Information Needs Of Family Members After Acquired Brain Injury: A Systematic Review, Craig Andrews, Alyson Norman, Sue Jackson, Mark Holloway Jan 2026

Understanding The Support And Information Needs Of Family Members After Acquired Brain Injury: A Systematic Review, Craig Andrews, Alyson Norman, Sue Jackson, Mark Holloway

School of Psychology

The aim of this systematic review was to (a) identify the specific information and support needs of family members caring for ABI survivors and (b) assess the effectiveness of current support systems and resources available. A comprehensive search of the literature was carried out, focusing on studies that were published between the years 2000 and 2025. Seventeen studies met the inclusion criteria. The review employed a narrative synthesis approach to collate findings across papers. The analysis identified five key themes: ABI Knowledge, The Strain of Unsupported Transitions, Emotional and Financial Cost, ABI Support Groups, and Supporting Social Connectedness. The findings …


Children And Adults Across 15 Countries Believe In Human Uniqueness Of Mind: A Cross-Cultural Investigation Of Cross-Species Mind Perception, Karri Neldner, Luke Maurits, Magie Junker, Lara Abbas, Nayrouz Abbas, Arianna Abis, Federica Amici, Bernardo Arroyo-Garcia, Negar Asghari, Giovanna Barragán Pardo, Zhen Zhang, Junior Peña Chumacero, Ardain Dzabatou, Dustin Eirdosh, Susan Hanisch, Tom Herrnsdorf, Tom Hovehne, Alicia Junker, Patricia Kanngiesser, Felipe Villa Larens, Safaa Mahmoud, Sandra Masaquiza, Iino Masato, Risma Illa Maulany, Tongtong Meng, Kardelen Mutlu, Putu Oka Ngakan, Ebru Peközer, Ljubica Petrović, Mirella Christy Rehatalanit Jan 2026

Children And Adults Across 15 Countries Believe In Human Uniqueness Of Mind: A Cross-Cultural Investigation Of Cross-Species Mind Perception, Karri Neldner, Luke Maurits, Magie Junker, Lara Abbas, Nayrouz Abbas, Arianna Abis, Federica Amici, Bernardo Arroyo-Garcia, Negar Asghari, Giovanna Barragán Pardo, Zhen Zhang, Junior Peña Chumacero, Ardain Dzabatou, Dustin Eirdosh, Susan Hanisch, Tom Herrnsdorf, Tom Hovehne, Alicia Junker, Patricia Kanngiesser, Felipe Villa Larens, Safaa Mahmoud, Sandra Masaquiza, Iino Masato, Risma Illa Maulany, Tongtong Meng, Kardelen Mutlu, Putu Oka Ngakan, Ebru Peközer, Ljubica Petrović, Mirella Christy Rehatalanit

School of Psychology

The way humans relate to other animals is fundamentally shaped by whether we perceive ourselves as unique, with feelings and thoughts not shared by other animals. How beliefs about animals’ ability to feel and think develop across cultures remains largely unexplored. We asked children and adolescents (4–17 years, N = 1025) and adults (N = 190) from 33 urban and rural communities across 15 countries whether animals have thoughts or feelings (judgments of presence), and whether those thoughts or feelings are human-like (judgments of similarity). Bayesian analyses revealed that participants generally ascribed non-human animals the ability for thoughts and feelings. …


Others’ Requests May Dampen The Desire To Do Good: The Effect Of Requests On Children's Prosocial Motivation Across Five Cultures., Anneliese Skrobanek, Patricia Kanngiesser, Jahnavi Sunderarajan, Jorge David Mantilla Salgado, Saiwa Sisa Quimbo Yacelga, Shoji Itakura, Marie M. Morita, Masanori Yamaguchi, Nadia Chernyak, Lucy M. Stowe, Joscha Kärtner Jan 2026

Others’ Requests May Dampen The Desire To Do Good: The Effect Of Requests On Children's Prosocial Motivation Across Five Cultures., Anneliese Skrobanek, Patricia Kanngiesser, Jahnavi Sunderarajan, Jorge David Mantilla Salgado, Saiwa Sisa Quimbo Yacelga, Shoji Itakura, Marie M. Morita, Masanori Yamaguchi, Nadia Chernyak, Lucy M. Stowe, Joscha Kärtner

School of Psychology

There exists cultural variation in how people react to prosocial obligations, but we still know little about when these differences emerge in development and how they can be explained. We investigated this in a study with 6- to 11-year-old children (N = 686) in five cultural contexts. Children listened to scenarios about spontaneous and requested (within-subjects) helping and sharing. They rated requested scenarios as less desirable and less satisfying, but there was significant cross-cultural variation in the magnitude of this effect, which was mostly stable with age. We also measured children's sense of individual agency and internalization of prosocial norms …


The Impact Of Value Homophily, Rational And Emotional Persuasion On Information Passing Of Social Media Advertisements: A Model Comparison Approach, Gloria Hui Wen Liu, Cecil Eng Huang Chua, Neil Chueh An Lee, Jenny Hua Jen Wu Jan 2026

The Impact Of Value Homophily, Rational And Emotional Persuasion On Information Passing Of Social Media Advertisements: A Model Comparison Approach, Gloria Hui Wen Liu, Cecil Eng Huang Chua, Neil Chueh An Lee, Jenny Hua Jen Wu

Business and Information Technology Faculty Research & Creative Works

Increasingly, businesses collaborate with influencers and content creators (the source) to advertise on social media, with social media users being exposed to an environment saturated with unsolicited advertisements. With social contacts remaining the most trusted advertisement sources, users' passing of such advertisements helps their dissemination and creates a specific kind of electronic word of mouth called information passing. Information passing involves users forwarding advertisements about products/services to someone else. Prior studies have found at least three factors influence information passing, including value homophily (similarity with the source as perceived by users), rational appeal (information about how a product can meet …


Hardware Without Humanware: Robot Adoption, Talent Structure Degradation, And Firm Innovation, Wenhao Sun, Zhenyu Wu, Chevy-Hanqing Fang Jan 2026

Hardware Without Humanware: Robot Adoption, Talent Structure Degradation, And Firm Innovation, Wenhao Sun, Zhenyu Wu, Chevy-Hanqing Fang

Business and Information Technology Faculty Research & Creative Works

Contrary to the prevailing view that automation complements skilled labor in advanced economies, this study examines the unintended consequences of robot adoption in emerging markets. Drawing on strategic human capital theory, we exploit China's manufacturing sector as a natural experiment to identify the causal impact of industrial intelligence on firm-level innovation. Using a unique dataset of more than 90,000 public and private firms from the National Enterprise Innovation Database (2008–2014), we uncover a counterintuitive result: robot adoption significantly reduces firm innovation, which is notably more pronounced for private-owned firms and those with weaker innovation capabilities. Mediation analyses further show that …


One Size Doesn’T Fit All: Navigating Gendered Ageism In Older Women’S Entry Into Entrepreneurship, Yanying Chen, Zijie Song, Chevy-Hanqing Fang Jan 2026

One Size Doesn’T Fit All: Navigating Gendered Ageism In Older Women’S Entry Into Entrepreneurship, Yanying Chen, Zijie Song, Chevy-Hanqing Fang

Business and Information Technology Faculty Research & Creative Works

Though older women may choose entrepreneurship as a way to escape discrimination in the labor market, they may face other forms of discrimination in the entrepreneurial domain. Drawing on intersectionality theory, we posit that older women encounter amplified discrimination due to the stereotype-consistent implications from gender and age norms, namely gendered ageism. Using 815,428 individual observations pooled across country–year surveys from 56 countries between 2009 and 2018, we found that older women were least likely to enter entrepreneurship. And this intersectional disadvantage could be mitigated by weakening the normative exclusion and possessing resource endowments that signal capability. However, strategies focused …


Gubernatorial Re-Election Incentives, Local Investment Bias, And Pension Fund Performance, Hongxian Zhang, Liang Guo, Jun Hao, Yu Liu Jan 2026

Gubernatorial Re-Election Incentives, Local Investment Bias, And Pension Fund Performance, Hongxian Zhang, Liang Guo, Jun Hao, Yu Liu

Business and Information Technology Faculty Research & Creative Works

We investigate the impact of gubernatorial re-election incentive and political factors on US public pension funds from 1990 to 2022. Our empirical analysis finds no significant overall relationship between gubernatorial re-election incentives and local bias in the full sample. However, the effect of gubernatorial re-election incentives on local bias is influenced by a state's level of corruption. Specifically, in states within the lowest corruption quantile, governors eligible for re-election tend to prioritize local investments to gain consistent support. In contrast, in states within the highest corruption quantile, heightened scrutiny may encourage re-election-eligible governors to adopt conservative investment policies that do …


Who Seeks Help? Characteristics Of Doctors Accessing Mental Health Support In England: 4-Year National Review, Rohit Shankar Jan 2026

Who Seeks Help? Characteristics Of Doctors Accessing Mental Health Support In England: 4-Year National Review, Rohit Shankar

Peninsula Medical School

BackgroundMental health difficulties affect the well-being of doctors and compromise the delivery of healthcare. However, large-scale data on doctors’ mental health needs are limited.AimsDescribe patterns of self-referrals for mental health support among doctors in England and explore associations with demographic factors, speciality, neurodevelopmental and mental health indicators.MethodObservational study using data from doctors who self-referred for mental health difficulties to a national service in England over a 4-year period. Logistic regression was used to explore associations between speciality and mental health indicators.ResultsOf the 16 815 doctors who self-referred during the study period, 80% were under the age of 49 and 70.6% …


Gelatinous Zooplankton As Indicators In The Kunming Montreal Global Biodiversity Framework, John Terenzini, Laura J. Falkenberg, Sanae Chiba, Matthew Faith, Robert Puschendorf, Abigail Mcquatters-Gollop Jan 2026

Gelatinous Zooplankton As Indicators In The Kunming Montreal Global Biodiversity Framework, John Terenzini, Laura J. Falkenberg, Sanae Chiba, Matthew Faith, Robert Puschendorf, Abigail Mcquatters-Gollop

School of Biological and Marine Sciences

Global biodiversity frameworks require robust, representative indicators to effectively track progress towards conservation targets. Spatial and temporal gaps in global marine biodiversity datasets, however, and a limited number of marine biodiversity indicators, limit our ability to effectively manage marine ecosystems. Despite the ecological and socio-economic significance of marine ecosystems, they remain underrepresented in current indicator suites, particularly in the recently adopted Kunming-Montreal Global Biodiversity Framework (KMGBF). Gelatinous zooplankton (GZ), a key yet often overlooked component of marine ecosystems, have the potential to strengthen biodiversity assessments through their responsiveness to environmental change and impacts on several contributions of the ocean to …


Post-Release Mortality Of European Bass (Dicentrarchus Labrax) Discarded From Small-Scale Estuarine Fishing, J. E. Stewart, T. Stamp, P. Davies, A. Hall, T. Robbins, L. Stewart, E. V. Sheehan Jan 2026

Post-Release Mortality Of European Bass (Dicentrarchus Labrax) Discarded From Small-Scale Estuarine Fishing, J. E. Stewart, T. Stamp, P. Davies, A. Hall, T. Robbins, L. Stewart, E. V. Sheehan

School of Biological and Marine Sciences

Estuaries provide essential habitats for many fish species, but their confined and accessible nature may increase fish vulnerability to capture, and few empirical studies have quantified the value of restricting net fisheries in such areas. Furthermore, management measures for some fisheries promote discarding (e.g., of European sea bass; Dicentrarchus labrax), yet the mortality of fish discarded from small-scale inshore fisheries is poorly understood. We used condition assessments, Reflex Action Mortality Predictor scores and acoustic tracking to evaluate post-release mortality of bass captured in small-scale estuarine netting and angling. Gillnet-caught bass exhibited a range of stress responses and 20%–24% mortality shortly …


Utilizing A Culture System For Horizontal Cells To Study Neural Circuit Assembly In The Developing Mouse Retina, Ross M Perez, Yong H Park, Ajeet Singh, Collin Todora, Marlon F Mattos, Daniela Becerril, Rajashree Venkatraman, Arlene A Hirano, Nicholas C Brecha, Rinki Ratnapriya, Benjamin J Frankfort, Elizabeth Zuniga-Sanchez Jan 2026

Utilizing A Culture System For Horizontal Cells To Study Neural Circuit Assembly In The Developing Mouse Retina, Ross M Perez, Yong H Park, Ajeet Singh, Collin Todora, Marlon F Mattos, Daniela Becerril, Rajashree Venkatraman, Arlene A Hirano, Nicholas C Brecha, Rinki Ratnapriya, Benjamin J Frankfort, Elizabeth Zuniga-Sanchez

Faculty, Staff and Students Publications

The precise wiring of the nervous system relies on neurons extending their processes at the right time and place to find their appropriate synaptic partner. The mechanisms that determine when and where neurons extend their neurites during synaptogenesis remains a central question in the field. In the present study, we used a cell culture system coupled with live imaging to investigate the wiring mechanisms in the developing mouse retina. We focused on horizontal cells which are a class of interneurons in the outer mouse retina known to synapse selectively to the distinct types of photoreceptors. Previous research has shown horizontal …


Integrating A Project-Based Learning Methodology Into A Department-Wide Quality Improvement Curriculum: A Nine-Year Experience In Pediatric Subspecialty Training, Venessa Lynn Pinto, Danny Castro, Constance M Wiemann, Liza Bonin, Cagri Yildirim-Toruner, Nicholas A Ettinger, Sharada Hiranya Gowda, Joyee Vachani, Mehmet Fatih Okcu Jan 2026

Integrating A Project-Based Learning Methodology Into A Department-Wide Quality Improvement Curriculum: A Nine-Year Experience In Pediatric Subspecialty Training, Venessa Lynn Pinto, Danny Castro, Constance M Wiemann, Liza Bonin, Cagri Yildirim-Toruner, Nicholas A Ettinger, Sharada Hiranya Gowda, Joyee Vachani, Mehmet Fatih Okcu

Faculty, Staff and Students Publications

Background: Quality improvement (QI) training of subspecialty fellows is an essential component of graduate medical education, yet often delivered in silos within departments through a variety of instructional methodologies.

Objective: We applied project-based learning (PjBL) as a guiding methodology for a QI curriculum for pediatric subspecialty fellows and describe our curriculum development, instructional design, and its implementation.

Methods: We integrated the Institute for Healthcare Improvement (IHI) Model for Improvement with the 6 key features of PjBL: a driving question, defined learning goals, active participation in educational tasks, collaboration among learners, scaffolding with learning technology, and production of tangible artifacts. The …


Charles Centerfit Hart-Kent Collection, University Of Alabama School Of Law Jan 2026

Charles Centerfit Hart-Kent Collection, University Of Alabama School Of Law

Manuscript Collections

The Charles Centerfit Hart-Kent Collection consists of documents related to Alabama attorney Charles Centerfit Hart, his 19th century ancestor, Elisha Hart, and several legal papers prepared for Elisha Hart's estate by Chancellor James Kent (1763-1847), attorney P.A. Sam, and other contributors. Also included in this collection is one second-edition copy of Chancellor Kent's publication, "Commentaries on American Law: Volume I" (1832).


Cecil Maxwell Deason Collection, University Of Alabama School Of Law Jan 2026

Cecil Maxwell Deason Collection, University Of Alabama School Of Law

Manuscript Collections

This collection contains personal papers and photographs from Alabama state trial court judge and assistant solicitor Cecil Maxwell Deason from his times serving in the Pacific theatre of WWII, on the bench in Jefferson county, and in the solicitor's office.


Mirza Anwer Beg Collection, University Of Alabama School Of Law Jan 2026

Mirza Anwer Beg Collection, University Of Alabama School Of Law

Manuscript Collections

This collection consists of a large number of books, files, photographs, and notebooks on topics ranging from Islam and Islamic/Arabic themes to poetry and art as well as topics on law, diplomacy, history, and philosophy.


Turner Reavis Collection, University Of Alabama School Of Law Jan 2026

Turner Reavis Collection, University Of Alabama School Of Law

Manuscript Collections

This collection includes documents, photographs, and materials pertaining to the life, career, and extended family history of Turner Reavis (June 18, 1812 - June 13, 1872). Reavis was a businessman, attorney, judge, state senator, and a published author.


Jay Wesley Murphy Collection, University Of Alabama School Of Law Jan 2026

Jay Wesley Murphy Collection, University Of Alabama School Of Law

Manuscript Collections

The Jay Wesley Murphy Collection is comprised of personal and professional papers, including arbitration case files, audiotapes, notes, transcripts of classroom presentations and discussions, and books.


Comparing Rotational Thromboelastometry And Standard Coagulation Assays For Predicting Intraoperative Bleeding In Pediatric Liver Transplantation, Kirby Deshotels, Trung Nguyen, Jun Teruya, Muhammed Umair M Mian, Kelby Fuller, Sanjiv Harpavat, Anna Banc-Husu, Amir Navaei, John Goss, Moreshwar Desai, Arun Saini Jan 2026

Comparing Rotational Thromboelastometry And Standard Coagulation Assays For Predicting Intraoperative Bleeding In Pediatric Liver Transplantation, Kirby Deshotels, Trung Nguyen, Jun Teruya, Muhammed Umair M Mian, Kelby Fuller, Sanjiv Harpavat, Anna Banc-Husu, Amir Navaei, John Goss, Moreshwar Desai, Arun Saini

Faculty, Staff and Students Publications

Background: Utility of preoperative rotational thromboelastometry (ROTEM) over standard coagulation assays (SCAs) in predicting intraoperative bleeding during orthotopic liver transplantation (OLT) in children with liver failure (LF) remains unclear.

Methods: In this single-center retrospective cohort of pediatric OLT recipients, we compared the predictive values of preoperative ROTEM parameters (intrinsic pathway (INTEM) maximum clot firmness (MCF), extrinsic pathway (EXTEM) clotting time (CT), INTEM CT, and fibrinogen-based (FIBTEM) MCF) and the corresponding SCAs (platelet count, international normalized ratio (INR), activated partial thromboplastin time (aPTT), and fibrinogen level, respectively) for significant intraoperative bleeding (blood loss of > 22 mL/kg; i.e., ≥ 85th percentile for …


On-Device Artificial Intelligence Solutions With Applications To Smart Environments, Fabrizio De Vita, Dario Bruneo, Sajal K. Das Jan 2026

On-Device Artificial Intelligence Solutions With Applications To Smart Environments, Fabrizio De Vita, Dario Bruneo, Sajal K. Das

Computer Science Faculty Research & Creative Works

Recent advances in Artificial Intelligence (AI) and the increasing availability of computational power have accelerated the diffusion of Intelligent Cyber-Physical Systems (ICPSs), enabling smart applications with reasoning capabilities. However, the limited resources of embedded and Edge devices significantly constrain the complexity of deep learning models that can be effectively deployed. Traditional approaches rely on cloud-based training and edge-only inference, a paradigm that becomes inadequate when low latency, privacy, security, and high customization are required. In this context, On-device AI is emerging as a new paradigm in which both training and inference are performed directly on the device, avoiding data transfer …


Fairrfl: Fair And Robust Federated Learning In The Presence Of Selfish Clients, Andrea Augello, Ashish Gupta, Giuseppe Lo Re, Sajal K. Das Jan 2026

Fairrfl: Fair And Robust Federated Learning In The Presence Of Selfish Clients, Andrea Augello, Ashish Gupta, Giuseppe Lo Re, Sajal K. Das

Computer Science Faculty Research & Creative Works

Federated Learning (FL) is a paradigm that enables collaborative machine learning without disclosing the local data of the participants. However, in real-world FL deployment scenarios, some unscrupolous clients may alter the training process to skew the global model towards their local optimum, unfairly prioritizing their data distribution. Their influence can degrade overall model performance for normal clients and reduce fairness in the system. We call this novel category of misbehaving clients 'selfish'. This work proposes a Fair and Robust strategy for aggregation in the Federated Learning (FL) server to mitigate the effect of Selfish clients (FairRFL). FairRFL incorporates a novel …


Smartflow: A Communication-Efficient Sdn Framework For Cross-Silo Federated Learning, Osama Abu Hamdan, Hao Che, Engin Arslan, Md Arifuzzaman Jan 2026

Smartflow: A Communication-Efficient Sdn Framework For Cross-Silo Federated Learning, Osama Abu Hamdan, Hao Che, Engin Arslan, Md Arifuzzaman

Computer Science Faculty Research & Creative Works

Cross-silo Federated Learning (FL) enables multiple institutions to collaboratively train machine learning models while preserving data privacy. In such settings, clients repeatedly exchange model weights with a central server, making the overall training time highly sensitive to network performance. However, conventional routing methods often fail to prevent congestion, leading to increased communication latency and prolonged training. Software-Defined Networking (SDN), which provides centralized and programmable control over network resources, offers a promising way to address this limitation. To this end, we propose SmartFLow, an SDN-based framework designed to enhance communication efficiency in cross-silo FL. SmartFLow dynamically adjusts routing paths in response …


Utility-Preserving Federated Graph Learning With Dual-Perspective Fairness, Renqiang Luo, Huafei Huang, Shuo Yu, Fengqi Yu, Feng Xia, Sajal K. Das, Chengqi Zhang Jan 2026

Utility-Preserving Federated Graph Learning With Dual-Perspective Fairness, Renqiang Luo, Huafei Huang, Shuo Yu, Fengqi Yu, Feng Xia, Sajal K. Das, Chengqi Zhang

Computer Science Faculty Research & Creative Works

Fairness-aware federated graph neural networks (FedGNNs) necessitate consideration of both the server and the clients. However, fairness-aware methods struggle to enhance dual-perspective (i.e., server and clients) fairness without sacrificing utility due to the distributed learning framework. As a consequence, the utility sacrifices of fairness-aware graph learning methods are even exacerbated in federated frameworks. In this work we propose F3GL, a dual-perspective fairness federated graph learning method that enhances both global (for the server) and local fairness (for clients) while preserving utility. Through theoretical analysis, we delineate the similarity between original sensitive features and those after convolution under different spectra. Our …


Establishing And Testing Experiential Critical Theory (Ect), Dolores M. Batten Mrs. Jan 2026

Establishing And Testing Experiential Critical Theory (Ect), Dolores M. Batten Mrs.

Graduate Studies Theses and Dissertations 2026

There is a current gap in academia which has been largely overlooked in both pedagogy and assessment: the value of personal experience as key evidence of interpretation and meaning-making correlation. Aside from narrative writing, most current methods of literary analysis writing do not place a high value on personal experience beyond the inclusion of brief anecdotes. Yet experience is the major pathway by which an individual forms their worldview, which then informs the ways in which they interpret the world—and by extension, text. This dissertation both establishes and examines the use of Experiential Critical Theory (ECT) in pedagogical application for …


The Place Between Places, Harrison Burke Jan 2026

The Place Between Places, Harrison Burke

Graduate Studies Theses and Dissertations 2026

The Place Between Places is a collection of essays centered on belonging. Focusing on the composition of city streets, theme parks, and hidden pockets of wonder, belonging is explored as the product of place and culture. The perspective of the collection shifts between reflection and active exploration, using present moment journeys as catalysts to unravel the past. In every new discovery there is a ghost, past and present journeys fighting for their place in the constructed narrative called “self.”

The collection primarily makes use of braided essays and nonlinear storytelling. “Animal” blends together three night walks through New York, Seoul, …


Reflection In Still Waters: Generative Ai's Production Of Language, Jonathan D. Hawks Jan 2026

Reflection In Still Waters: Generative Ai's Production Of Language, Jonathan D. Hawks

Graduate Studies Theses and Dissertations 2026

Language is a conceptual process of meaning-making as well as a social construction as defined by Saussure, Bakhtin, and Lacan. Large Language Models (LLMs) engage with neither process and instead present language as a finished and consumable product which undermines its fundamental aspects. The difference between representing language through probability and its structural components instead of its more inherent qualities is not a pointless distinction. This paper utilizes Narcissus as a central metaphor to show how people misread the outputs of LLMs as language which imparts to those reflected words meaning on par with our own conceptualizations of reality. People …


Between The Living And The Dead, Leona Strong Jan 2026

Between The Living And The Dead, Leona Strong

Graduate Studies Theses and Dissertations 2026

Between the Living and the Dead is a collection of short stories and flash fiction that explores loss, generational abuse, abandonment, the sometimes brutal power of familial ties, and love in its many forms—both good and evil. This thesis aims to tease out, in the reader, moments of reflection, compassion and revelation. “Falling,” centers on a mother’s grief after her son dies by suicide and her attempt to move beyond perceived culpability and shame. She does this by jumping from a plane to embody his last moments and make the same decision…to live or to die. “And Baby Makes One,” …


Fgf19 As A Colorectal Cancer Serum Biomarker And Fgfr4 As A Mediator Of Anti-Her2 Resistance In Breast Cancer, Jordan Beardsley Jan 2026

Fgf19 As A Colorectal Cancer Serum Biomarker And Fgfr4 As A Mediator Of Anti-Her2 Resistance In Breast Cancer, Jordan Beardsley

Graduate Studies Theses and Dissertations 2026

The fibroblast growth factor 19 (FGF19)-fibroblast growth factor receptor 4 (FGFR4) signaling pathway regulates hepatic metabolism, bile acid (BA) synthesis, and hepatocyte proliferation. This signaling axis also is implicated in promoting tumor progression, therapeutic resistance, and metastasis in certain cancers.

In colorectal cancer (CRC) there is a critical need for non-invasive biomarkers for disease detection and monitoring. We identified FGF19 as a candidate CRC serum marker through meta-transcriptomics and found FGF19 to be expressed and secreted by CRC cell lines. Tumor-derived FGF19 was detectable in mouse serum at levels correlating with tumor volume in a subcutaneous xenograft model. RNA sequencing …


Exploring The Experiences Of Late Age-On-Arrival Multilingual Learners In Postsecondary Education, Robyn D. Ecklund Jan 2026

Exploring The Experiences Of Late Age-On-Arrival Multilingual Learners In Postsecondary Education, Robyn D. Ecklund

Graduate Studies Theses and Dissertations 2026

Multilingual learners (MLs) are the fastest growing population in the United States public school system (Biondi et al., 2024; Kanno & Cromley, 2013; Perez & Morrison, 2016; Varghese & Fuentes, 2020). Within this population of students, there is a subset of students that arrive in the United States during secondary school. These “late age-on-arrival” students face significant linguistic, cultural and social challenges in their pursuit of postsecondary success after high school (Kanno, 2021; Kanno & Cromley, 2013; Perez & Morrison, 2016). This interpretative phenomenological analysis sought to answer the research question: what are the lived experiences of late age-on-arrival MLs …


Investigating The Anti-Apoptotic Properties Of The N-Terminus Of The Chlamydia Trachomatis Effector Tarp, Kasey S. Jordan Jan 2026

Investigating The Anti-Apoptotic Properties Of The N-Terminus Of The Chlamydia Trachomatis Effector Tarp, Kasey S. Jordan

Graduate Studies Theses and Dissertations 2026

As the most prevalent bacterial STI in the United States and leading cause of infection-related blindness worldwide, the obligate intracellular bacteria, Chlamydia trachomatis (Ct), poses a significant threat to public health. As an obligate intracellular bacteria, invasion of the host cell is a crucial step in Chlamydia’s developmental cycle. To drive invasion, Ct injects prepackaged effectors into the host cell using a T3SS. An early Chlamydial effector, translocated actin recruiting phosphoprotein, or Tarp, interacts with host cell actin to promote invasion, mediated via Tarp’s C-terminal region. Although the function of Tarp’s C-terminus is well defined, the Tarp’s N-terminus …


Investigating The Impact Of School Leaders’ Leadership Style And Teachers’ Intrinsic Motivation For Improved Science Instruction In Elementary Schools, Leila M. Greene Jan 2026

Investigating The Impact Of School Leaders’ Leadership Style And Teachers’ Intrinsic Motivation For Improved Science Instruction In Elementary Schools, Leila M. Greene

Graduate Studies Theses and Dissertations 2026

A report by the National Academies of Sciences, Engineering, and Medicine, determined that 69% of U.S. elementary teachers are not prepared to teach science, especially in the areas of earth/space and physical sciences. As a result, some elementary teachers avoid teaching science. School administrators play a key role in providing a supportive environment to inspire and motivate elementary science teachers. For this reason, the study utilized the Self-Determination Theory (SDT), to examine three types of school leadership styles (Transformational, Transactional, and Laissez-Faire) and how they impact the intrinsic motivation for elementary science teachers in three areas including autonomy, competency, and …