Digital Commons Network^™

The Effects Of Fitness Self-Testing With Instant Feedback On Changes In Health-Related Fitness Among Chinese Male College Students, Yongshun Wang, Xiaofen D Hamilton, Rulan Shangguan, Anlu Yang, Na Xiao, Chenhao Wu, Sizhe Liu, Ren Yang, Jiren Zhang, Mark F Hamilton

Faculty, Staff and Student Publications

Background: The decline in health-related physical fitness resulting from physical inactivity remains a critical global public health concern. Technology-supported fitness self-testing has the potential not only to improve students' testing experiences but also to enhance their health-related fitness. However, the effectiveness of such approaches has not yet been systematically examined, and their validity within university populations remains largely unestablished.

Method: A quasi-experimental research design with a control group (n = 45) and an experimental group (n = 44), incorporating pre- and post-tests, was employed in this study. The experimental group completed monthly self-testing sessions accompanied by GAI-generated instant feedback over …

The Lysine Demethylase Kdm4c Is An Oncogenic Driver And Regulates Erk Activity In Kras-Mutant Pancreatic Ductal Adenocarcinoma, Menna-T-Allah Shaheen, Sarah Dhebat, Kimal I Rajapakshe, Bidyut Ghosh, Benson Chellakkan Selvanesan, Shariq S Ansari, Cara L Haymaker, Dorsay Sadeghian, Huamin Wang, Ching-Fei Li, Haoqiang Ying, Anirban Maitra

Faculty, Staff and Student Publications

Deregulation of proteins involved in chromatin regulation is common in pancreatic ductal adenocarcinoma (PDAC). Lysine demethylase 4C (KDM4C) is one of the chromatin-modifying proteins frequently overexpressed across multiple solid cancers and is linked to chromatin instability, increased cell proliferation, and enhanced stem cell–like behavior. We observed upregulation of KDM4C protein in a panel of human PDAC cell lines and patient samples compared with nonneoplastic controls. CRISPR/Cas9-mediated deletion of KDM4C in human and murine PDAC cells reduced proliferation, clonogenicity, and increased survival of orthotopically implanted murine PDAC allografts. Transcriptomic and proteomic analyses revealed that loss of KDM4C in both human and …

Clinical And Molecular Characteristics Of Patients With Young-Onset And Average-Onset Pancreatic Adenocarcinoma, Adriana C Gamboa, Kever A Lewis, Laura R Prakash, Zhouxuan Li, Wei Qiao, Dan Zhao, Mark W Hurd, Mahmoud Yousef, Naruhiko Ikoma, Michael P Kim, Jeffrey E Lee, Jessica E Maxwell, Ching-Wei D Tzeng, Matthew H G Katz, Rebecca A Snyder

Faculty, Staff and Student Publications

Purpose: The incidence of young-onset pancreatic cancer (YO-PC) has risen over the past two decades, yet its molecular characteristics and long-term outcomes remain poorly defined.

Methods: We retrospectively evaluated patients with PC treated at a tertiary referral center from 2016 to 2022 who had available molecular data. Patients were classified as YO-PC (≤50 years) or average-onset PC (AO-PC, >50 years). A subset analysis examined outcomes in those who underwent curative-intent pancreatectomy. Primary end points included overall survival (OS) and recurrence-free survival (RFS).

Results: Among 511 patients, 10.9% had YO-PC (n = 56; median age 44 years). Patients with YO-PC more …

Case Report: Management Of A Challenging Case Presenting With Dysphagia After Thyroidectomy Requiring Administration Of Liquid 131i Via Mic-Key Low-Profile Tube—A Multidisciplinary Approach, Ahmed Ebada Salem, Sandra Ramirez, Brian R Weston, Akram Hussein, Simone Krebs

Faculty, Staff and Student Publications

Radioactive iodine (RAI) therapy with 131-iodine (131I) remains a cornerstone in the postoperative management of differentiated thyroid carcinoma (DTC). The standard route of administration is oral, typically in capsule form and less commonly as a liquid. However, in patients with severe dysphagia and compromised airway, traditional oral 131I delivery may be contraindicated due to the risk of aspiration and radioactivity contamination. These scenarios present unique clinical challenges that necessitate deviation from conventional protocols. While liquid 131I may be administered through the mouth or via nasogastric or percutaneous gastrostomy tubes, there is currently no standardized approach, and potential risks, such as …

Initial Experience With Remote Mri Scanning Support In An Oncology Focused Practice: Opportunities For Expanded Access To Radiology Care, Christopher M Walker, Maria G Maldonado, Megan C Jacobsen, Suprateek Kundu, Michelle L Underwood, Joshua P Yung, Brandy J Reed, David Jaffray, R Jason Stafford, Marshall E Hicks, Caroline Chung, Aradhana M Venkatesan

Faculty, Staff and Student Publications

Background: As medical imaging demand grows, there is increasing stress on the currently available workforce to deliver consistent, high-quality imaging studies while ensuring rapid study turnaround times and round-the-clock radiology coverage. Advances in remote access technology facilitating remote scan assistance and control are now commercially available to address these pressing clinical needs.

Methods: This work evaluated an early clinical application of a virtual scanner operations system (syngo Virtual Cockpit (VA13A, Siemens Healthineers, Erlangen, Germany) for remote magnetic resonance imaging (MRI) monitoring and scan control at three geographically distant outpatient sites associated with our primary institution.

Results: The system facilitated execution …

Preliminary Examination Of Orexin Receptor Antagonism With Suvorexant In Individuals With Methamphetamine Use Disorder: A Case Series Study, Heather Webber, Jessica Badawi, Douglas Calvillo, Jin Yoon, Michael Weaver, Scott Lane, Joy Schmitz

Faculty, Staff and Student Publications

No abstract provided.

Evolving Molecular Subtypes Of Gastric Cancer: From Past Classifications To Present Consensus And Future Directions For Precision Therapy, Ju-Seog Lee

Faculty, Staff and Student Publications

Gastric cancer is a biologically heterogeneous disease. The advent of high-throughput multi-omic technologies has revolutionized our understanding of gastric cancer by deconstructing this heterogeneous entity into distinct and more homogeneous molecular subtypes. Early classifications based on gene expression, methylation, and histology have laid the groundwork for multi-omic frameworks proposed by The Cancer Genome Atlas and Asian Cancer Research Group, which established the foundation of modern molecular taxonomy. Subsequent integrative efforts, particularly the Consensus Genomic Subtypes (Super 6) model, have unified this collected information into clinically relevant subtypes that bridge prognostic stratification with treatment strategies. Established biomarkers such as human epidermal …

Bop2-Te: Bayesian Optimal Phase 2 Design For Jointly Monitoring Efficacy And Toxicity With Application To Dose Optimization, Kai Chen, Heng Zhou, J Jack Lee, Ying Yuan

Faculty, Staff and Student Publications

We propose a Bayesian optimal phase 2 design for jointly monitoring efficacy and toxicity, referred to as BOP2-TE, to improve the operating characteristics of the BOP2 design proposed by Zhou et al. (2017). BOP2-TE utilizes a Dirichlet-multinomial model to jointly model the distribution of toxicity and efficacy endpoints, making go/no-go decisions based on the posterior probability of toxicity and futility. In comparison to the original BOP2 and other existing designs, BOP2-TE offers the advantage of providing rigorous type I error control in cases where the treatment is toxic and futile, effective but toxic, or safe but futile, while optimizing …

Prickle4 Drives Microenvironmental Remodeling And Resistance To Parp Inhibition In Idh-Mutant Glioma, Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T Huse, Bo Chen, Timothy A Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang

Faculty, Staff and Student Publications

Mutations in isocitrate dehydrogenase (IDH) genes sensitize gliomas to PARP inhibition (PARPi) by inducing epigenetic reprogramming of DNA damage repair circuits. However, tumors treated with PARPi eventually relapse despite initial responsiveness. In this study, it is demonstrated that the anti-angiogenic agent lenvatinib synergizes effectively with PARPi, resulting in substantial tumor regression and significantly extended survival. Genomic analysis of tumors reveals that PARPi induces widespread transcriptomic changes that are predominantly pro-inflammatory, thereby promoting tumor angiogenesis. Prickle4, a planar cell polarity protein, is identified as a critical mediator of PARPi-induced neovascularization. Targeting Prickle4 effectively overcomes PARPi resistance in these tumors. Collectively, these …

A Gut-Activated Nhr-86-Cyp Pathway Mediates The Neuroprotective Effects Of Enterococcus Faecium Probiotics In A Nematode Model Of Amyotrophic Lateral Sclerosis, Yu Sang, Jie Ren, Alejandro Aballay

Faculty, Staff and Student Publications

Neurodegenerative diseases are often associated with oxidative stress, and while probiotics may influence neuronal health, the underlying mechanisms remain poorly understood. Using the sod-1 A4VM amyotrophic lateral sclerosis (ALS) model in Caenorhabditis elegans, we investigated the protective effects of the probiotic Enterococcus faecium against oxidative stress-induced neurodegeneration. Animals fed E. faecium showed reduced motor neuron degeneration under oxidative stress compared to those maintained on a standard Escherichia coli diet. Transcriptome analysis revealed a significant enrichment of oxidoreductase genes, including cytochrome P450 (cyp) genes. RNAi-mediated knockdown of cyp genes impaired E. faecium-mediated neuroprotection, and this loss correlated with increased reactive oxygen …

Guadecitabine Improved Relapse-Free Survival In High-Risk Acute Myeloid Leukemia And Myelodysplastic Syndrome Patients After Transplant: Phase Ii Results From A Single Center, Betül Oran, Peter Thall, Amin Alousi, Gheath Al-Atrash, Rohtesh Mehta, David Marin, Partow Kebriaei, Uday Popat, Roland Bassett, Qaiser Bashir, Jin Im, Amanda Olson, Jessica Jewell, Portia Smallbone, Elizabeth Shpall, Richard Champlin

Faculty, Staff and Student Publications

This phase II, single-center clinical trial evaluated the efficacy and safety of guadecitabine, with or without donor lymphocyte infusion, following allogeneic stem cell transplantation in adult patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). The study had three treatment cohorts based on post-transplant disease status. Cohort 1 included patients with hematologic relapse after transplant (N=13). Cohort 2 consisted of patients with minimal residual disease (MRD) detected after transplant (N=18). Cohort 3 compromised patients in remission without MRD within 100 days after transplant (N=24). The primary objectives were achievement of morphological complete remission in cohort 1 and MRD eradication …

Endogenous Processes Underlying Clock-Like Mutational Signatures, Teresa Druck, Rami I Aqeilan, C Marcelo Aldaz, Nicola Zanesi, Kay Huebner

Faculty, Staff and Student Publications

Wellcome Trust scientists have shown that “mutational signatures” in specific nucleotide contexts accumulate in genomes of mammalian tissues, providing clues to underlying causes of specific signatures. Analysis of cancer genomes has identified more than 50 single‐base substitution (SBS) signatures, with SBS1, SBS5, and SBS40 linked to aging and present in normal tissues. SBS1 results from cytosine demethylation, whereas SBS5 and SBS40 arise from unknown endogenous mechanisms. We hypothesized that loss of fragile‐site genes drives these two signatures. FHIT, located at FRA3B, is frequently deleted in cancers, and Fhit‐deficient mouse tissues exhibit a mutation profile resembling human SBS5. Data mining of …

Preclinical Ischemic Stroke Multicenter Trials (Prism) Collective Statement: Opportunities, Challenges, And Recommendations For A New Era, Cenk Ayata, Philip M Bath, Anna M Planas, Stuart M Allan, Johannes Boltze, Ryan P Cabeen, Claire L Gibson, Marilyn J Cipolla, Marcio A Diniz, Stefano Fumagalli, Fahmeed Hyder, Raymond C Koehler, Arthur Liesz, Sarah K Mccann, Tim Magnus, Louise D Mccullough, Emily S Sena, Simone Beretta, Jaroslaw Aronowski, Francesca Bosetti, Clinton B Wright, Patrick D Lyden, Lauren H Sansing

Faculty, Staff and Student Publications

Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials. mpRCTs offer advantages such as increased sample sizes, robust statistical design, incorporation of heterogeneity, and standardized protocols, but they face challenges in finding the right balance between standardization and heterogeneity, appropriate stroke model selection, and outcome measures, as well as the …

Intratumoral Bacteria Are Immunosuppressive And Promote Immunotherapy Resistance In Head And Neck Squamous Cell Carcinoma, Natalie L Silver, Jin Dai, Travis D Kerr, Jessica Altemus, Rekha Garg, Hannah Simmons, Tyler Alban, Laura Noel-Romas, Vladimir Makarov, David J H Shih, Shwetha V Kumar, Akeem Santos, Rehan Akbani, Adam Burgener, Mohammed Dwidar, Neil Gross, Andrew G Sikora, Elias J Sayour, Apollo Stacy, Christian Jobin, Timothy A Chan, Renata Ferrarotto, Daniel J Mcgrail

Faculty, Staff and Student Publications

Despite the promise of immune checkpoint blockade (ICB) in head and neck squamous cell carcinoma (HNSCC), mediators of response are poorly understood. To address this, here we analyzed oropharyngeal HNSCCs treated with neoadjuvant durvalumab (anti-PDL1) alone or in combination with tremelimumab (anti-CTLA4) from the CIAO clinical trial ( NCT03144778 ). We found that only the total abundance of intratumoral bacteria predicted ICB response, which was validated in multiple independent cohorts. High intratumoral bacteria abundance was associated with an immunosuppressive tumor microenvironment, characterized by an accumulation of neutrophils coupled with depletion of T cells and other adaptive immune cells. Experimental elevation …

Expanding Professional Practice For Pre-Service Teachers Through Online International Engagement, Rhonda Di Biase, Katrina Burge, Sarah Baldacchino, Ann Dongyu Gu

Australian Journal of Teacher Education

This study investigated the professional learning of pre-service teachers (PSTs) involved in an international online project, known as the International Literacy Project, that evolved during the Covid-19 pandemic. The project promotes international engagement across diverse sites, with sessions in classes centred around storytelling and story-making across a range of countries. Using vignettes, the study explored how involvement in the project presented additional opportunities for personal and professional learning for the PSTs through interacting with the diverse international settings. We considered the learning opportunities from such international online engagement, the usefulness of expanded opportunities for professional practice and how Zoom enabled …

Indicators Of Mid-Career Teacher Quality Through Perspectives Of Key Stakeholders, Maria Azfar Karimullah, Wayne G. Cotton, Louisa Peralta

Australian Journal of Teacher Education

The ongoing quest of quality education has focused on teaching quality in K-12 classrooms globally, as evidenced by recent research, reviews, and media coverage. Yet, identifying, defining, and measuring ‘teacher quality’ remains a complex challenge, particularly during the crucial mid-career stage. The focus on mid-career teachers in educational research is often neglected, when compared with early career teachers or teachers in leadership. This qualitative study explores the characteristics that mid-career teachers, teacher leaders and accreditation personnel perceive as the indicators of a quality mid-career teacher. Drawing on semi-structured interviews with 29 participants including 23 mid-career teachers, five school principals, and …

Induction For Non-Beginning Teachers: An Attempt To Connect Induction To Continuous Professional Development, Gulcin Cosgun, Derin Atay

Australian Journal of Teacher Education

Since there is limited research exploring the impacts of induction on the teaching practices of newly recruited experienced teachers, in this paper, findings of a study whose purpose is to explore the impacts of a comprehensive induction model on non-novice teachers in regards to their teaching practices will be reported. 11 mentees involved in a mandatory comprehensive induction program at the English preparatory school in a Turkish foundation university participated in this study. The observation data collected at three phases- the onset of the induction program at the beginning of the first year, on completion of the program at the …

Provoking Generative Ai Futures: Merging Theory And Praxis, Regina M. Luttrell Ph.D., Nick Bowman

Media Studies - All Scholarship

An accessible exploration of the myriad applications and challenges of generative AI for media and communication students, scholars, and practitioners alike.

The latest emergence of increasingly low-cost and scalable AI technologies presents a point of both celebration and concern for the contemporary media and information ecosystem. To this end, this edited volume gathers media and communications scholars and practitioners to engage in discussions and exchange ideas about current trends and developments in the field. Questions this volume asks include: What are the essentials of generative AI from a media and communication perspective? How has generative AI influenced research and scholarship? …

Meat Is Dead, Melissa D. Mortazavi

Faculty Articles

The legal and cultural landscape surrounding meat in the United States is evolving as plant-based alternatives, GMO farm animals, and cell-cultivated meat move from test tube to table. While global demand for meat rises amid environmental, ethical, and resource challenges, cell-cultivated meat emerges as a scientifically viable alternative, offering identical nutritional value without the drawbacks of conventional livestock production. Despite federal regulatory approval from USDA and FDA, multiple states have enacted unusually restrictive laws—including bans— targeting cell-cultivated meat. These are motivated largely by economic protectionism, but also deeper cultural anxieties tied to tradition and identity. This Article argues that food …

What Is Terrorism?, Karl T. Muth, Alice Locatelli

Journal of Air Law and Commerce

Is Gotham's Joker a terrorist? What about a school shooter? As we approach the twenty-fifth anniversary of the 9/11 attacks, the United States still lacks a monolithic legal definition of 'terrorism,' creating a dangerous 'motive gap' between federal statutes. This Article analyzes the friction between the motive-heavy definition of 'domestic terrorism' in Title 18 (which includes a mens rea aspect) and the conduct-focused definition of 'terrorist activity' in Title 8 (which focuses on overt acts). Using the hijacking of Flight 93 and the Columbine shootings as case studies, we demonstrate how Title 18's political requirement creates a coverage void for …

Critical Feminist Editorial Praxis: My Tenure As The First Journal Editor Of Color Of Communication Monographs, Srivi Ramasubramanian

Media Studies - All Scholarship

In this essay I theorize about Critical Feminist Editorial Praxis, which envisions journal editing as a site for scholar-activism. I use the term activism because to counter the hegemonic whiteness and coloniality of Communication knowledge requires active efforts to go against the taken-for-granted processes and practices. Journal editing is a significant location for interventions because this is often where we learn what is considered cutting-edge scholarship within our discipline. This significance is especially clear when the journal in question is a flagship publication of a leading professional organization. As I end my tenure as the first editor of color of …

The Role Of Media Literacy In Shaping Campus Student Leaders’ Perceptions Of Media Activism, Online Risks, And Social Support, Srivi Ramasubramanian, Minnie Mcmillian, Shumaila Bhatti, Shannon Burth, Julius Matthew Riles, Elizabeth Behm-Morawitz, Melody Wilson

Media Studies - All Scholarship

Campus activism by student leaders has historically played a significant role in social movements. Within contemporary contexts, media is an important site through which campus student leaders raise awareness, share relevant information, distribute online petitions, and shape public discourses on various social issues. Media literacy is an essential skill for student leaders to be effective in their activist initiatives and be able to cope with the inevitable pushback through trolling and cyberbullying that such activism would likely bring up. This survey (N = 855) with college student leaders across three universities explores how they rate themselves on media literacy skills, …

Spa 309 - Spanish Advanced Grammar, Beatriz Lado, Evelyn Duran-Urrea, Tania Avilés

Open Educational Resources

This syllabus is a work in progress developed by Tania Avilés, Evelyn Durán Urrea, and Beatriz Lado. We adapt the traditional grammar-focused course to introduce the study of the Spanish language through a critical sociolinguistic and language-education lens. This approach responds more directly to the needs of our students, many of whom speak language varieties that have historically been stigmatized or marginalized and are training to become Spanish-language teachers.

Students will examine the structure and grammar of Spanish across key domains, including phonetics, morphology, syntax, semantics, pragmatics, discourse, and variation. At the same time, the course situates this structural knowledge …

Enhancing Phonemic Awareness Through Explicit Instruction In A Kindergarten Classroom: An Action Research Study, Emily M. Caylor

Graduate Research Papers

This action research study examined the implementation of early phonemic awareness exposure and the impact of an Elkonin Box multisensory Tier II support focused on segmentation, blending, isolation, and manipulation. The study involved a small group of kindergarten students with varied backgrounds over a fifteen-week period. Data collection included a pre-assessment, four bi-weekly progress checks, and a post-assessment. Results indicated a connection between the implementation of the Tier II support and student growth over time. The researcher recommends this Tier II support as a complement to core instruction to strengthen phonemic awareness development. For classroom teachers, the study highlights the …

Economic Value Of Agro-Meteorological Services: A Review Of The International Literature, Joseph Manzvera, Kwabena Asomanin Anaman

All Rsif Scholars' Publications

Introduction:

The increasing frequency and intensity of climate-induced extreme weather events, such as droughts, have significantly reduced agricultural productivity worldwide. Enhancing access to agro-meteorological services can mitigate these impacts by improving farmers’ decision-making and adaptive capacity. However, their economic value remains poorly understood, especially in African countries where meteorological services are provided as public goods. Demonstrating their value is critical to stimulate investment and strengthen climate-resilient agriculture.

Methods:

This study reviews and synthesises empirical evidence on the economic value of agro-meteorological services through a systematic literature review and meta-analysis of international studies. Both peer-reviewed and grey literature were analysed to …

Agroclimatic Sensing, Communication, And Computational Systems-Based Methods And Technologies For Precision Irrigation Management: Current State And Prospects, Aminata Sarr, Abhilash K. Chandel, Lamine Diop Lamine Diop, Yrébégnan Moussa Soro, Alain K. Tossa, Smrutilipi Hota, Arunachalam Manimozhian

All Rsif Scholars' Publications

Agriculture uses most of the world’s fresh water. Given that the worldwide population is expanding at an alarming rate, more land cultivation is apparently in demand. As a result, much more water would be required to irrigate cultivable lands. However, fresh water is becoming scarce at a faster rate due to climate uncertainties and over-exploitation. Several controlled irrigation techniques, such as drip and sprinkler irrigation, have been introduced to safeguard water resources. However, these techniques do not readily meet crop water demands and often end up causing overapplication of water. Under these circumstances, smart precision irrigation is the best solution. …

Developing Provider Digital Twins For Personalized Provider-Patient Communication Via A Rag-Based Conversational Framework, Pengze Li, Yutong Hu, Jianfu Li, Garit Gemeinhardt, Fang Li, Muhammad Amith, Licong Cui, Antonio J Forte, Cui Tao

Faculty, Staff and Student Publications

Digital twins have emerged as a paradigm in precision and personalized medicine, enabling data-driven modeling of individuals to support tailored interventions. While most existing work focuses on patient-oriented twins, little attention has been given to modeling the provider’s role, particularly in clinical communication. In this study, we present GRACE (Generalized RAG-Enhanced Conversation Framework), a framework for constructing a provider digital twin (ProDT) that emulates key aspects of clinicians’ communicative and cognitive behavior. GRACE integrates three modules: a physician-informed dialog script generation and optimization module for provider-patterned conversation, a Retrieval-Augmented Generation (RAG) pipeline for factual grounding and timely knowledge updating, and …

Paying Up To Uncle Sam: Fbar Penalties, The Eighth Amendment’S Excessive Fines Clause, And A New Circuit Split, Christopher J. Nasta

Western New England Law Review

The Bank Secrecy Act requires those with foreign financial accounts to file a Report of Foreign Bank and Financial Accounts (FBAR) with the United States Department of the Treasury’s Financial Crimes Enforcement Network (FinCEN). Those who do not file are subject to a variety of criminal and civil penalties.

The Eighth Amendment of the United States Constitution provides that excessive fines cannot be levied by the American government against individuals. How does this apply to those with foreign financial accounts who willfully choose not to file the required reporting forms with the United States government? A circuit split has arisen …

Evolving Execution Methods: The Constitutionality Of Nitrogen Hypoxia Through Pain, Precedent, And Practicality, Reem Haikal

Western New England Law Review

Method-of-execution challenges have intensified as lethal injection protocols face chronic instability. This Article evaluates whether execution by nitrogen hypoxia violates the Eighth Amendment and argues that it does not. The analysis applies Baze and Glossip to two questions: whether nitrogen hypoxia presents a substantial risk of severe pain and whether a feasible and readily implemented alternative would materially reduce that risk. This Article synthesizes historical Eighth Amendment principles with the contemporary record from executions by nitrogen hypoxia, related litigation materials, medical testimony, and physiological literature on inert-gas hypoxia.

The evidence indicates that nitrogen hypoxia typically produces rapid loss of consciousness …

A Cautionary Tale: A Case For Abolishing The Addict-Inpossession Statute On Constitutional Grounds, Jonathan Bruce

Western New England Law Review

Are drug users second-class citizens under the Second Amendment? The Federal Government enacted the Gun Control Act in 1968 which imposed heaps of new regulations relating to private gun ownership, including enacting criminal statutes, namely 18 U. S. C. §922(g), which allows an individual to face charges if that individual is categorized under any of § 922(g)’s enumerated subsections. In 2010, the United States Supreme Court issued its landmark decision in District of Columbia vs. Heller, establishing the right of the people to own and possess firearms for self-defense, regardless of any association with “the militia” as described in the …