Digital Commons Network^™

Variants In Dennd2b Are Associated With Vulnerability For Neurodevelopmental Impairment, Psychosis And Catatonia, Harsha Murthy, Ny Hoang, Jamie C Stark, Sunny Cui, Emanuela Pannia, Chung Ting Tsoi, Simon Harris, C'Airah Ceolin, Lauren Verhaeghe, Sydney Scholten, Danielle Baribeau, Jane Summers, Gregory Costain, Thanuja Selvanayagam, Jennifer L Howe, M E Suzanne Lewis, Theresa Brunet, Susanne Rieger, Jill A Rosenfeld, William J Craigen, Lindsay C Burrage, Michelle R Christie, Deborah Baldwin, Ingrid M Wentzensen, Boris Keren, Benjamin Cogne, Bertrand Isidor, Alexandra Afenjar, Reem M Elshafie, Laila Bastaki, Sumaya Alkanderi, Kenneth A Myers, Scott Demarest, Katie Angione, Megan Abbott, Philippe M Campeau, James J Dowling, Roberto Mendoza-Londono, Stephen W Scherer, Ashish R Deshwar, Jacob Vorstman

Faculty, Staff and Students Publications

DENND2B is a DENN (differentially expressed in normal and neoplastic cells) domain-containing protein that has important roles in regulating the cell cycle, cell division and ciliogenesis, but to date has not been associated with any human disease.

Here, we report on 11 individuals with monoallelic variants in DENND2B with a shared constellation of features and perform in silico and in vivo zebrafish modelling of the DENND2B variants identified in these patients.

Features shared among these patients include developmental delay, intellectual disability and psychiatric/behavioural concerns, and episodes of psychosis and/or catatonia. Additional features common to our cohort include epilepsy, muscle weakness/hypotonia …

Costs And Cost-Effectiveness Of A Culturally Adapted Diabetes Self-Management And Education Program For Marshallese Adults, Tzeyu L Michaud, Daniel Lamprecht-Carson, Su-Hsin Chang, Clare C Brown, Jennifer A Andersen, James P Selig, Philmar Mendoza Kabua, Pearl Mcelfish

2020-Current year OA Pubs

BACKGROUND: Culturally adapted diabetes self-management education (DSME) programs are effective in improving glycemic control and diabetes outcomes among minority populations, but data on program costs and cost-effectiveness are limited. This study aimed to assess the cost and cost-effectiveness of a culturally adapted DSME (adapted DSME) compared to a standard DSME model among Marshallese adults with type 2 diabetes (T2D).

METHODS: Retrospective cost and cost-effectiveness analyses (CEA) were conducted using data from the community-based trial, conducted between May 2015 and May 2018. We applied an activity-based costing approach to quantify the implementation resources. The CEA was performed using an incremental implementation …

Analysis Of Lake Toba Ecoliteracy In High School Students, Jesika Aurelia Sianipar, B Manurung, Martina Asiati Napitupulu, Abdul Hakim Daulae

Jurnal Pendidikan Sains

The Lake Toba ecosystem is currently experiencing increasingly worsening quality degradation, so that instilling environmental awareness through ecoliteracy has become urgent in the world of education. This study aims to measure the ecoliteracy abilities of students at High School 1 Ajibata and High School 2 Balige by reviewing three main aspects: cognitive, affective, and behavioral. Additionally, it will analyze the differences in ecoliteracy levels between the two schools. The type of research used is ex post facto with a quantitative approach. Data were collected through test instruments for the cognitive aspect and questionnaires for the affective and behavioral aspects. The …

The History Of Teaching Indonesian In The United States And Its Pedagogical Shift In The Late 20th Century, Eko Widianto, G.G. Weix, Michael Cullinane

Journal of Southeast Asian American Education and Advancement

The history of teaching Indonesian in the United States has received limited scholarly attention, despite the field's existence for over eighty years. This study traces its development and identifies three main phases. The first phase began during World War II, when Indonesian was taught primarily to meet military needs through a structural and drill-based approach. In the 1960s and 1970s, instruction was restructured to support academic research, with teaching materials and classroom practices aimed at developing reading skills and preparing students for fieldwork. From the late twentieth century onward, Indonesian programs increasingly adopted communicative approaches influenced by broader trends in …

Book Review: Quit: The Power Of Knowing When To Walk Away, Cam Caldwell

The Journal of Values-Based Leadership

No abstract provided.

Book Review: Lessons From History: The Courage To Lead: The Leadership Legacy Of Theodore Roosevelt And Why It Matters Today, Elizabeth Gingerich

The Journal of Values-Based Leadership

No abstract provided.

The Power Of Choice: Transformative Moments In The Lives Of Biblical Heroes, Hershey H. Friedman, Linda Weiser Friedman

The Journal of Values-Based Leadership

This paper examines pivotal moments in the lives of key biblical figures and explores how these choices shaped both personal destinies and spiritual legacies. Biblical narratives depicting the lives of Adam, Noah, Joseph, Judah, Moses, Ruth, Boaz, David, Solomon, Zerubbabel, Esther, Mordechai, and Samson illustrate that these transcendent moments involve significant moral choices. We see that even revered figures can experience moral failings, and that some individuals can achieve greatness through singular acts of moral courage. These momentous decisions – whether acts of bravery, failures of judgment, vengeance versus reconciliation, worldly power versus spiritual calling, or moments of redemption—reveal profound …

Change Management With Ethical Leadership, Sophia Rudisill Holmes

The Journal of Values-Based Leadership

Ethical leadership ensures organizational environments are created and nurtured to support complex dilemmas that surface during change management. Leaders and followers in particular can navigate change management with intentional advance planning guided by the motives of their heart. The motives of a leader’s heart is observed by the ethical practices of their core values. Morally leaders and followers core values inform their ethical behaviors. Furthermore, Christian leaders have access to biblical scripture which provides a roadmap for leaders and followers in the mastery of adapting and not resisting during change management. Biblical scriptures also provide examples of practices that solve …

Living Ethically: An Inner Capacity Struggling To Become A Moral Reality, Joseph P. Hester

The Journal of Values-Based Leadership

Spiritual refinement is a part of our essential moral self. As a seedbed of moral consciousness, spiritual refinement is a perpetual activity, as well as a reservoir of experiences, needed for shaping the world and responding to its ethical demands. Begun as moral insight and utilizing the moral imagination, the actual details and social structures of morality are developed and applied in real life situations where they mature and change as they overlap and are tempered by others.

Curiosity, Courage, And Complexity: Leadership Lessons From My Dad, Elizabeth A. Luckman

The Journal of Values-Based Leadership

Some of the most important leadership lessons don’t come from classrooms or boardrooms—they come from the people who coach us through life’s turning points. For me, that coach was my Dad. An engineer turned leadership coach, he taught me that curiosity, courage, and the ability to navigate complexity are the foundation of ethical leadership. In this editorial, I share three of his favorite phrases and the values they carry: get curious before reacting, be courageous by starting to experiment, and check your assumptions because sometimes the problem is your lens, not your limits. Along the way, I connect these lessons …

Winter/Spring 2026

The Journal of Values-Based Leadership

No abstract provided.

生成式语言模型在自动写作评估中的早期综述：自动作文评分与反馈 生成领域的进展、挑战及方向, Yue Huang, Corey Palermo, Ruitao Liu, Yong He

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

自动写作评估（AWE）长期以来在写作测评与教学中发挥着重要作用，但现有系统在捕捉学生写作中更深层次的修辞结构与教学相关特征方面仍存在不足。近年来，生成式语言模型（GLM）如 GPT 和 Llama 的快速发展为 AWE带来新机遇，但其效能尚未得到充分验证。本综述综合了 29 项关于自动作文评分的研究和 14 项关于自动写作反馈生成的研究，系统探讨了 GLM 在提示工程、微调与适应性策略中的应用。研究表明，GLM 在模拟人类评分与生成符合评分标准的反馈方面展现出潜力，但公平性、效度与伦理等关键问题仍亟待解决。GLM 有望显著提升 AWE 系统的表现，但前提是未来研究需建构稳健的评估框架与保障机制，以确保其在教育实践中负责任、公平地应用。

A Treasure Hunt: The Interdisciplinary Challenge Of A Digital Humanities Hackathon, Marie Barras, Adélaïde Quenson, Adrien Jeanrenaud, Angela Allemand, Marina Berazategui, Levyn Bürki, Michel Capot, Simon Gabay, Vestin Hategekimana, Pauline Jacsont, Bokar Lamine N'Diaye, Elina Leblanc, Clara May, Anne-Laure Oberson, Margherita Parigini, Lara Pitteloud, Fassaleh Taal, Cédric Viaccoz

Artl@s Bulletin

Abstract: This article tells the story of an interdisciplinary hackathon emphasizing exploration, collaboration, and creative engagement with globalization-related cultural datasets. Participants worked in teams to produce research posters, which were then presented at the opening of the international conference Image Deluge & Globalization in Geneva. The article discusses three projects: one on 19th-century Spanish chapbooks using topic modeling and network analysis; another on leopard motifs in print imagery; and a third on olfactory heritage. The hackathon highlighted both the potential and the limitations of working with digital cultural data, offering insights into interdisciplinary methods.

Résumé: Cet article raconte un hackathon …

Mapping The Multifarious Image In Time Of Globalization, Anne-Laure Oberson

Artl@s Bulletin

Abstract: In this paper, I examine the evolving concept of the image, exploring the philosophical implications of its complex, multifaceted nature. I question the value of terms such as icon, simulacrum, and image in reference to Gilles Deleuze’s text Difference and Repetition. I argue for a pluralistic approach to understanding images as they embody more than a duality of visible-invisible dimensions. I seek to capture the multifariousness of the image to understand its transformative power. In conclusion, the paper suggests reevaluating image discourse to better engage with the evolution of its implications in a global context.

Résumé: Dans cet …

Queens, Pearls And Spirochaetes, Radu Suciu

Artl@s Bulletin

Abstract: In December 2019, the New Zealand AIDS Foundation (now the Burnett Foundation) released a public health campaign raising awareness about the increasing rates of syphilis infections in New Zealand. The campaign consisted of photographs that contrasted contemporary backgrounds of bars and nightclubs with actors wearing theatrical costumes akin to the Elizabethan period. This reinforced the perceived idea that syphilis was a disease resurging from the distant past. This paper discusses one of the campaign’s most iconic portraits by analysing its shared cultural, artistic, and medical references (explicit or implicit) and their shifting meanings through time.

Résumé: En décembre 2019, …

Roaming Pixels: Clipping The Operative Close-Up, Vanessa Gravenor

Artl@s Bulletin

Abstract: This essay examines the disseminated war image as it takes off at the speed of light. It seeks to challenge the legacy of the post-structuralist spectator who watches war by complicating this figure with post-colonial perspectives where the distanced, global war dissemination collapses into the intimate, subjective gaze. Focusing on artist–theorist perspectives, it traces strategies for working with the digital broadcast of war, specifically from the 2000s and 2010s, and artists who peer into uncertain pixels and the cruelty of the close-up.

Zusammenfassung: In diesem Essay wird das verbreitete Kriegsbild untersucht, das mit Lichtgeschwindigkeit abhebt. Er versucht, das Erbe …

Brute Force Branding: Variations & Repetitions Of The Almighty Dollar Banknote, Rui-Long Monico

Artl@s Bulletin

Abstract: This paper examines the U.S. dollar as a global brand and mythic icon, revealing how its stable aesthetic asserts dominance and infiltrates daily life. Through visual analysis and global comparison, it shows how banknotes are battlegrounds where art, identity, and geopolitics collide—currency as a weapon of soft power and cultural hegemony. The dollar’s visual inertia—ritualized, repeated, reappropriated—cements its supremacy as a symbolic force, where repetition enforces authority and variation sparks both resistance and conformity. Banknotes emerge as tools of statecraft and vessels of collective memory, as reflected in the author’s bespoke creation accompanying this study.

Résumé: Cet article analyse …

Image Circulations And Economic Imagination: Framing The Peruvian And Chilean Peripheries At The End Of The 19th Century, Alexandre Puche

Artl@s Bulletin

Abstract: This study explores two cases of photographic circulation between Peru, Chile and France in the late nineteenth century to show how images contributed to the requalification of the region within global commercial geography. It also proposes a historical methodology that considers visual repetition as a traceable product of transnational circulation. This approach sheds light on both certain mechanisms behind Atlantic propaganda regarding South America’s economic potential and the structuring role such circulations played in shaping regional representations.

Résumé: Cette étude examine deux cas de circulations photographiques entre le Pérou, le Chili et la France à la fin du XIXe …

Antimicrobial Resistance Of Cultivable Bacteria Isolated From Sorcerer’S Cave In Texas, Jennifer R. Huddleston, David E. Sanderson, Braden J. Smith, Joshua M. Brokaw, Evan M. Babb, Jeffrey T. Wooliscroft

International Journal of Speleology

Studying caves with minimal human contact offers insights into antimicrobial resistance before human influence. In this study, we isolated 315 bacterial strains from Sorcerer’s Cave in Texas and evaluated their resistance to seven common antimicrobials. Under half (41.4%) of the Gram-positive isolates and 68.4% of the Gram-negative isolates were resistant to three or more antimicrobials. The two most common genera identified were Pseudomonas and Bacillus. Compared to bacteria isolated in previous cave studies, Sorcerer’s Cave bacteria exhibited more extensive antimicrobial resistance. This study underscores the importance of minimally disturbed cave environments in advancing our knowledge of antimicrobial resistance present …

“A Questionable Culture That Has Dominated Rté For Too Long”: Early Funding Structures And The Nature Of Irish Public Service Media, Roddy Flynn

Irish Communication Review

RTÉ is unusually reliant on advertising revenue in comparison with other European public service media. This article suggests that understanding why this is the case requires a look at the longer history of RTE’s finances, back to the era when the broadcasting service was directly run as an element of the Department of Posts and Telegraphs and thus, indirectly, the Irish state. This status notwithstanding, a sequence of government decisions in the 1930s created a situation whereby the public service medium became reliant on advertising income for its survival, a dependency relationship which not only persisted but became even more …

Discovering New Music: Curators In Irish Radio, Ciarán Ryan

Irish Communication Review

From the arrival of pirate radio stations to the establishment of RTÉ 2FM and the later introduction of commercial radio, Irish audiences have had access to various forms of popular music radio for over half a century. Non-chart or ‘alternative’ music programming is a part of the Irish radio landscape that has been under-researched until now. Primarily scheduled late at night, these programmes have had hosts who have fostered intimate connections with smaller, niche audiences through their musical knowledge and personally selected track listings. Looking at industry perspectives from various strands of broadcasting in Ireland, this research examines the value …

Crystal Sets And Listening-In: Radio In Ireland Before 2rn, Stephanie Rains

Irish Communication Review

When 2RN began broadcasting from its studios on Henry Street in Dublin on 1 January 1926, it became the first radio station in the Free State. However, it was very far from being the start of radio on the island of Ireland, as there was already a community of amateur operators and engineers conducting technical experiments. This article explores the radio landscape in Ireland which 2RN joined and transformed. The early enthusiasts often not very concerned with programming or with most of radio’s possibilities as a form of entertainment, but did have a very international perspective on the medium’s possibilities. …

Icr Radio Centenary Issue: Table Of Contents And Bios, Rosemary Day

Irish Communication Review

No abstract provided.

The Centenary Of Radio In Ireland 2026: Introduction To Special Issue Of Irish Communications Review, Rosemary Day

Irish Communication Review

This article introduces the special issue of Irish Communications Review, 2026, that celebrates the centenary of radio in Ireland. It discusses the aims and aspirations announced on the first night of broadcasting, 1st January 1926 and gives details of the vision shared by Douglas Hyde on that night. It briefly describes the content of each of the seven articles in the special issue. Each one is based on new research and each one investigates a different aspect of the development of Irish radio over the past one hundred years and considers the implications and impact of those developments.

Assessing The Effects Of Ehealth Literacy And The Area Deprivation Index On Barriers To Electronic Patient Portal Use For Orthopedic Surgery: Cross-Sectional Observational Study, Audrey Lynn Litvak, Nicholas Lin, Kelly Hynes, Jason Strelzow, Jeffrey G Stepan

2020-Current year OA Pubs

BACKGROUND: As electronic patient portals (EPPs) continue to gain popularity and systems transition to online tools for scheduling, communication, and telehealth, patients without access or skills to use these tools may be overlooked.

OBJECTIVE: This study analyzed patient and neighborhood-level factors, including eHealth literacy level and the Area Deprivation Index (ADI), that may limit EPP access for orthopedic surgery.

METHODS: A cross-sectional, survey-based study was performed at a single urban tertiary academic medical center in the United States across foot and ankle, hand and upper extremity, and orthopedic trauma subspecialty clinics from June 21, 2022, to August 12, 2022. Survey …

A Policy Reversal As Structural Break: A Lesson From China’S Land Lease Financing For Infrastructure, Yilin Hou, Lin Li, Lei Shao

Center for Policy Research

Land-based revenues as a fiscal instrument to finance infrastructure tie public investment to real estate markets, where demand fluctuations cause fiscal consequences. This paper takes policy reversals as structural breaks and examines their impacts on infrastructure investment. We dissect China’s 2016 policy reversal that disallowed developers to finance land purchase with debt, causing sharp declines in local government land revenues, slashing their fiscal base for infrastructure investment. Using prefecture-level panel data and continuous difference-in-differences identification, we estimate the reversal reduced land-lease revenues by 55%. Two-stage least squares estimates suggest a 10% land-revenue decline translates into 6.6% investment reduction. Decomposing the …

Collaborating With ‘Blue Food’ System Stakeholders To Achieve Optimal Nutritional Health And Wellbeing In Less Affluent Communities, Clare Pettinger, Louise Hunt, Carol Wagstaff

School of Health Professions

UK food system transformation is urgently needed, but to date, minimal research has investigated ‘blue foods’ probably because they are ethically nuanced. There exists a paradox whereby materially deprived communities should be eating more fish to meet nutritional requirements, yet there is a global ‘red flag’ around global overfishing. New collaborative and creative solutions are, therefore, needed to tackle such food system inequities. By working together, all voices can be equally heard when decisions are being made to improve the system. Similarly, innovation and disruption of established supply chains will enable better access to healthy, affordable and tasty food that …

Glossary-Augmented Generative Ai For Enterprise Translation, Tanmay Kayande, Deep Raithatha, Akash Dambhare, Pooja Agrawal, Mohith P

Defensive Publications Series

Global enterprise operations can experience inefficiencies and service delays from language-siloed support queues, while generic machine translation tools may lack the context to handle enterprise-specific terminology. A system and method can facilitate multilingual communication by integrating a generative artificial intelligence model within enterprise workflow platforms, such as customer relationship management systems. The framework can programmatically retrieve a curated, enterprise-specific glossary and inject it into a translation prompt sent to the model. This technique grounds the model, instructing it to prioritize an organization's specific lexicon for a given translation. The approach can produce translations that are both linguistically fluent and terminologically …

Priestly Christology And Holiness: Christ’S Priesthood And The Sanctification Of Believers, Adriani Rodrigues

Faculty Publications

No abstract provided.

Exploring Parenting Experiences: Fathers And Mothers Raising A Child With Autism, Simmi Santha

Walden Dissertations and Doctoral Studies

The experiences of parenting a child with autism spectrum disorder (ASD) have been widely studied in Western contexts. Still, limited research has explored how sociocultural factors shape these experiences in India. This qualitative study aims to address this gap by exploring and comparing the lived experiences of mothers and fathers raising a child with ASD in Kerala, India. The purpose of this study was to investigate how gender roles, cultural expectations, and social structures impact parental adaptation, coping, and caregiving practices. Bronfenbrenner’s ecological systems theory and Crenshaw’s ideas of intersectionality provide the conceptual framework of this study. Using an interpretative …