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2026

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Measuring Lawyer Mental Illness: Evidence From Two National Surveys, Benjamin David Pyle, Clifford Rosky Jan 2026

Measuring Lawyer Mental Illness: Evidence From Two National Surveys, Benjamin David Pyle, Clifford Rosky

Faculty Scholarship

The American Bar Association declared a “well-being crisis” among lawyers, but the empirical basis for this claim has been contested in recent years. This study systematically compares two high-quality, nationally representative surveys —the National Health Interview Survey (NHIS) and the National Survey on Drug Use and Health (NSDUH)—to measure the prevalence of mental illness and alcohol misuse among lawyers. In both surveys, lawyers report elevated rates of alcohol misuse compared to the general public and similarly educated peers. The NHIS finds that lawyers experience psychological distress at rates lower than the general public and similar to, or moderately higher than, …


Obscurity And The Fallacy Of No Privacy In Public Information, Woodrow Hartzog Jan 2026

Obscurity And The Fallacy Of No Privacy In Public Information, Woodrow Hartzog

Faculty Scholarship

The main thesis of this chapter is that because there are so many different possible interpretations of ‘public information’, the concept cannot be used to justify data practices and surveillance without first articulating a more precise meaning that recognises what is at stake. By disposing of the myth that there is an objective and dispassionate concept of public information, judges and lawmakers can clear the way for information rules based on overt value choices. In short, if the concept of ‘public’ is going to shape people’s social and legal obligations, its meaning and neutrality should not be assumed.

My argument …


Five Lessons From Ken Kersch’S Conservatives And The Constitution For The Present Moment, James E. Fleming, Linda C. Mcclain Jan 2026

Five Lessons From Ken Kersch’S Conservatives And The Constitution For The Present Moment, James E. Fleming, Linda C. Mcclain

Faculty Scholarship

Timothy Snyder’s On Tyranny, a New York Times bestseller, has the subtitle, “Twenty Lessons from the Twentieth Century.” Ken Kersch’s Conservatives and the Constitution: Imagining Constitutional Restoration in the Heyday of American Liberalism (2019) provides at least twenty lessons from the second half of the Twentieth Century about the development of conservative constitutional thought and activism. Although conservatism has changed in many ways since the 1954-1980 period on which Kersch’s book focuses, these lessons are relevant for understanding the present political moment, filled with concerns that the U.S., during the second Trump Administration, is lurching toward tyranny, authoritarianism, and …


The Hypocrisy Of Data Governance, Zubair Shafiq, Olivia Figueira, Athina Markopoulou, Woodrow Hartzog, Michael Lavine Jan 2026

The Hypocrisy Of Data Governance, Zubair Shafiq, Olivia Figueira, Athina Markopoulou, Woodrow Hartzog, Michael Lavine

Faculty Scholarship

“Data governance” is an empty term, like a Rorschach inkblot just waiting to be filled with meaning. Tech companies take advantage of this ambiguity to craft narratives about their data-governance capabilities to fit their audience and purpose. On one hand, tech companies brag about their data-governance capabilities when it fits their business model (for example, to advertisers) and public image (for example, to their customers). On the other hand, tech companies claim that meaningful data governance is challenging or impossible when accountability is demanded.

In this Article, we argue that tech companies systematically misrepresent or selectively ignore their data-governance capabilities. …


Corporate Law's Duty Of Data Loyalty, Andy Serwin, Neil Richards, Woodrow Hartzog, Ryan Durrie Jan 2026

Corporate Law's Duty Of Data Loyalty, Andy Serwin, Neil Richards, Woodrow Hartzog, Ryan Durrie

Faculty Scholarship

Privacy law used to be a relatively tidy field, involving a few interesting but discrete topics like press disclosures of private facts, wiretapping, and the processing of personal data by internet companies. But as the digital revolution continues to disrupt area after area of human activity and software “is eating the world,” the core concerns of privacy law such as “when is it appropriate to process personal data?” have similarly entered field after field. Today, most fields of law, including discrimination law, antitrust, and international law, have found it necessary to reckon with the questions of informational harm and power …


Regulating Crisis Pregnancy Centers After Nifla And Dobbs: Controversies Over When Government Is Imposing An Orthodoxy About Abortion, Linda C. Mcclain Jan 2026

Regulating Crisis Pregnancy Centers After Nifla And Dobbs: Controversies Over When Government Is Imposing An Orthodoxy About Abortion, Linda C. Mcclain

Faculty Scholarship

How does this broader sense of Barnette’s proscription of government from imposing “what shall be orthodox” implicate governmental restrictions on reproductive autonomy? Battles over reproductive freedom centrally implicate objections that government is unconstitutionally imposing a gender orthodoxy. Arguments for a right of personal autonomy embodying an antitotalitarian principle of liberty are arguments for a right to resist governmental imposition of an orthodoxy— for example, an idea about the natural or traditional role of women as mothers together with a view about how best to respect the sanctity of life. Rights to reproductive autonomy, grounded in personal autonomy and equality, …


Reaching The Intrinsic Performance Limits Of Superconducting Nanowire Single-Photon Detectors Up To 0.1 Mm Wide, Kristen M. Parzuchowski, Eli Mueller, Bakhrom G. Oripov, Benedikt Hampel, Ravin A. Chowdhury, Sahil R. Patel, Daniel Kuznesof, Emma K. Batson, Ryan Morgenstern, Robert H. Hadfield, Varun B. Verma, Matthew D. Shaw, Jason P. Allmaras, Martina J. Stevens, Alex Gurevich, Adam N. Mccaughan Jan 2026

Reaching The Intrinsic Performance Limits Of Superconducting Nanowire Single-Photon Detectors Up To 0.1 Mm Wide, Kristen M. Parzuchowski, Eli Mueller, Bakhrom G. Oripov, Benedikt Hampel, Ravin A. Chowdhury, Sahil R. Patel, Daniel Kuznesof, Emma K. Batson, Ryan Morgenstern, Robert H. Hadfield, Varun B. Verma, Matthew D. Shaw, Jason P. Allmaras, Martina J. Stevens, Alex Gurevich, Adam N. Mccaughan

Physics Faculty Publications

Superconducting nanowire single-photon detectors combine high detection efficiency, low noise, and excellent timing resolution, making them a leading platform for photon-counting applications. However, despite decades of materials and fabrication research, detector performance has never been shown to match theoretical performance expectations. Here, we demonstrate in situ tuning of a detector from its typical, suboptimal operation, to a regime limited only by material quality, allowing the device to reach its intrinsic performance limit. Our approach is based on current-biased superconducting “rails” placed on either side of the detector that redistribute current across its width to achieve peak performance. This technique reduces …


Real-Time Neck Posture Classification Using A Lightweight Wearable Imu Pendant, Muntaser Syed, Alfred Sjöqvist, Noah Sedlik, Tsing Liu Jan 2026

Real-Time Neck Posture Classification Using A Lightweight Wearable Imu Pendant, Muntaser Syed, Alfred Sjöqvist, Noah Sedlik, Tsing Liu

Electrical Engineering and Computer Science Student Publications

Poor neck posture during prolonged device use contributes to musculoskeletal disorders affecting millions worldwide. Existing posture monitoring solutions rely on camera-based systems or complex multi-sensor arrays, limiting their practicality for continuous daily use. We present a lightweight, chest-worn pendant using a single 6-axis IMU (accelerometer and gyroscope) for real-time classification of seven neck posture states: neutral, mild flexion, moderate flexion, severe flexion, extension, lateral tilt, and lying. Our approach employs an ensemble architecture combining bidirectional LSTM, Transformer encoder, and 1D-CNN models with learnable fusion weights. To address limited training data, we apply aggressive data augmentation (30x multiplication) including noise injection, …


Dystop: Dynamic Staleness Control And Topology Construction For Asynchronous Decentralized Federated Learning, Yizhou Shi, Qianpiao Ma, Yan Xu, Junlong Zhou, Ming Hu, Yunming Liao Jan 2026

Dystop: Dynamic Staleness Control And Topology Construction For Asynchronous Decentralized Federated Learning, Yizhou Shi, Qianpiao Ma, Yan Xu, Junlong Zhou, Ming Hu, Yunming Liao

Research Collection School Of Computing and Information Systems

Federated Learning (FL) has emerged as a potential distributed learning paradigm that enables model training on edge devices (i.e., workers) while preserving data privacy. However, its reliance on a centralized server leads to limited scalability. Decentralized federated learning (DFL) eliminates the dependency on a centralized server by enabling peer-to-peer model exchange. Existing DFL mechanisms mainly employ synchronous communication, which may result in training inefficiencies under heterogeneous and dynamic edge environments. Although a few recent asynchronous DFL (ADFL) mechanisms have been proposed to address these issues, they typically yield stale model aggregation and frequent model transmission, leading to degraded training performance …


Purified Zero-Shot Sketch-Based Image Retrieval, Yang Zhou, Jingru Yang, Jin Wang, Kaixiang Huang, Guodong Lu, Shengfeng He Jan 2026

Purified Zero-Shot Sketch-Based Image Retrieval, Yang Zhou, Jingru Yang, Jin Wang, Kaixiang Huang, Guodong Lu, Shengfeng He

Research Collection School Of Computing and Information Systems

Sketches, as a new solution in multimedia systems that can replace natural language, are characterized by sparse visual cues such as simple strokes that differ significantly from natural images containing complex elements such as background, foreground, and texture. This misalignment poses substantial challenges for zero-shot sketch-based image retrieval (ZS-SBIR). Prior approaches match sketches to full images and tend to overlook redundant elements in natural images, leading to model distraction and semantic ambiguity. To address this issue, we introduce a distraction-agnostic framework, purified cross-domain matching (PuXIM), which operates on a straightforward principle: masking and matching. We devise a visual-cross-linguistic (VxL) sampler …


“Well Done, My Good And Faithful Servant”: Ai-Generated Religious Imagery, White Evangelical U.S. American Christian Nationalism, And Political Martyrdom, Miriam Wolff Jan 2026

“Well Done, My Good And Faithful Servant”: Ai-Generated Religious Imagery, White Evangelical U.S. American Christian Nationalism, And Political Martyrdom, Miriam Wolff

Faculty Publications - Communications

Following the 2025 assassination of conservative activist Charlie Kirk, social media platforms became saturated with AI-generated religious imagery framing him as a Christian martyr. This article examines how generative AI intensifies the production of sacred political meaning within white evangelical U.S. American Christian nationalist discourse. Focusing on Senator Ted Cruz's X post depicting Jesus embracing Kirk alongside the caption “Well done, My good and faithful servant,” this study employs rhetorical-iconographic analysis informed by visual rhetoric, iconography, and political theology. The analysis demonstrates how the post mobilizes familiar Christian visual conventions, scriptural language, and algorithmic circulation to frame Kirk's death as …


Hybridization Of Genetic Algorithm, Principal Component Analysis And Deep-Learning For Networks Intrusion Detection Systems, Mostafa A. R. Eltokhy, Hend M. A. Mahmoud, Mohammad Sammany Jan 2026

Hybridization Of Genetic Algorithm, Principal Component Analysis And Deep-Learning For Networks Intrusion Detection Systems, Mostafa A. R. Eltokhy, Hend M. A. Mahmoud, Mohammad Sammany

Trends in advanced sciences and technology

With cyber-attacks on the rise, the demand for precise and efficient Intrusion Detection Systems (IDS) is more critical than ever. Traditional machine learning methods struggle with high false alarm and poor detection rates. IDS are crucial for creating secure digital environments by classifying and responding to network intrusions. However, the large volume of inputs for classification often leads to reduced accuracy and misclassification errors. To address this problem, Principal Component Analysis (PCA) is used to optimize the number of classifier inputs, enhancing simplicity without compromising accuracy. A significant challenge in PCA for feature selection lies in determining the best cutoff …


Prediction Of Phytocompounds For Environmental Sustainability: A Framework Using Computational Tools, Ankita Halder, Sayoni Dam, Sisir Nandi, Asmita Samadder Jan 2026

Prediction Of Phytocompounds For Environmental Sustainability: A Framework Using Computational Tools, Ankita Halder, Sayoni Dam, Sisir Nandi, Asmita Samadder

Trends in advanced sciences and technology

In response to the abruptly elevated environmental impact caused by the usage of chemical-based synthetic compounds in agricultural fields and pharmaceutical pollution, phytocompound-based products have become the choice of use for their ability to foster environmental sustainability. The potential of new phyto-based compounds has been explored in agriculture, phytoremediation, etc. Computer-based in silico prediction through ADMETlab 2.0, SwissADME, and Way2Drug software secured an important role in screening of these phyto-based compounds in terms of lethal concentration (LC50FM, LC50DM), Bioconcentration Factors, IGC50, and role in the TOX21 pathway ahead of their environmental exposure. These aforementioned softwares also …


Modelling And Optimization Of Solution Polymerization Of Ethylene Using Artificial Intelligence, Owolabi, R.U, Raji M.A, Usman M.A Jan 2026

Modelling And Optimization Of Solution Polymerization Of Ethylene Using Artificial Intelligence, Owolabi, R.U, Raji M.A, Usman M.A

Trends in advanced sciences and technology

This research project focuses on the modeling and optimization of the solution polymerization of ethylene, using artificial intelligence (AI) via machine learning (ML) tools specifically PYTHON programming language enabled workspaces (jupyter notebook and google colab). The objective of the research was to develop a robust empirical model capable of predicting the polymer yield and mol. wt. based on key process parameters, and to identify optimal conditions that maximize yield and mol. wt. while ensuring operational safety and efficiency.

A comprehensive dataset containing process parameters gotten from previous experimental works was used for model development while predicting missing parameters to ensure …


Enhanced Hydrophilicity And Self-Cleaning Properties Of Tio₂ Thin Films On Glass For Photovoltaic Applications: Influence Of Precursor Concentration And Light Irradiation, Fatma Refaat, Hany Hashem, Mohamed Mahmoud Gouda, Ibrahim Ahmed, Khaled Abdelwahed, Ahmed Bakr El Basaty Jan 2026

Enhanced Hydrophilicity And Self-Cleaning Properties Of Tio₂ Thin Films On Glass For Photovoltaic Applications: Influence Of Precursor Concentration And Light Irradiation, Fatma Refaat, Hany Hashem, Mohamed Mahmoud Gouda, Ibrahim Ahmed, Khaled Abdelwahed, Ahmed Bakr El Basaty

Trends in advanced sciences and technology

This study investigates the modification of glass substrates with TiO₂ thin films to enhance surface hydrophilicity and self-cleaning behavior. The films were deposited on glass by spin coating using different precursor concentrations, followed by thermal treatment. Structural and optical properties were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and UV–Vis spectroscopy, while surface wettability was evaluated through water contact angle measurements. XRD confirmed the formation of pure anatase TiO₂, while FTIR spectra verified the presence of Ti–O and Ti–O–Ti bonds. Wettability analysis showed that films prepared with the lowest precursor concentration exhibited the …


Probabilistic Reactive Power Planning With Static Synchronous Compensators Deployment In Renewable-Rich Power Systems Using The Cuckoo Catfish Optimizer, Mohammed Sonbol Ebrahim M.Sonbol, Omar Hanafy Abdalla Omar H. Abdalla, Hady Habib Fayek Hady H. Fayek, Abdulla Mohammed Shaheen Abdulla M. Shaheen Jan 2026

Probabilistic Reactive Power Planning With Static Synchronous Compensators Deployment In Renewable-Rich Power Systems Using The Cuckoo Catfish Optimizer, Mohammed Sonbol Ebrahim M.Sonbol, Omar Hanafy Abdalla Omar H. Abdalla, Hady Habib Fayek Hady H. Fayek, Abdulla Mohammed Shaheen Abdulla M. Shaheen

Trends in advanced sciences and technology

This paper presents a cost-optimized reactive power planning framework to determine the optimal location and ratings of Static Synchronous Compensators in renewable-rich power systems. The proposed methodology formulates a comprehensive cost-objective function that incorporates both investment and operational costs while considering normal and contingency (N−1) operating condition. Load variability and uncertainties associated with solar irradiance and wind speed are incorporated into the cost fitness function. These uncertainties are modeled using the point estimation method, generating 144 probabilistic scenarios that represent both daytime and nighttime operating conditions. The proposed approach ensures the minimum required number of Static Synchronous Compensators while maintaining …


Neuroprotective Effects Of Flaxseed And Purslane Extracts Against Cerebral Ischemia/Reperfusion Injury: Modulation Of Apoptotic, Neurotrophic, And Neurotransmitter Signaling, Fatma M. Attia, Ahmed E. Abdel Moneim, Rehab E. El-Hennamy, Inas S. M. Elsayed, Gehad E. Elshopakey, Nabil A. El-Yamany Jan 2026

Neuroprotective Effects Of Flaxseed And Purslane Extracts Against Cerebral Ischemia/Reperfusion Injury: Modulation Of Apoptotic, Neurotrophic, And Neurotransmitter Signaling, Fatma M. Attia, Ahmed E. Abdel Moneim, Rehab E. El-Hennamy, Inas S. M. Elsayed, Gehad E. Elshopakey, Nabil A. El-Yamany

Trends in advanced sciences and technology

Background: Cerebral ischemia/reperfusion (I/R) injury is a serious pathological condition that leads to permanent neurological impairment. Plant-derived bioactive compounds are gaining attention as promising neuroprotective therapeutic alternatives with relatively low adverse effects. Aims: This study aimed to investigate the neuroprotective effects of flaxseed extract (FE) and purslane extract (PE) on I/R injury in rats.

Methods: Seventy adult male rats were divided into seven groups: control, sham, I/R model, FE, FE-pretreated I/R, PE, and PE-pretreated I/R. Cerebral ischemia was induced by occlusion of the bilateral common carotid arteries for 60 min, followed by 120 min reperfusion. Rats were treated orally with …


Report On A Gpr Survey Of The Copper Harbor Cemetery, Copper Harbor, Michigan, Grace Griffin Jan 2026

Report On A Gpr Survey Of The Copper Harbor Cemetery, Copper Harbor, Michigan, Grace Griffin

Dissertations, Master's Theses and Master's Reports

The Copper Harbor Cemetery in Grant Township, Michigan, is one of the oldest settler cemeteries in the Keweenaw, with the earliest burial dating back to 1853. The cemetery is also still used by the community today. However, consistent burial records have not been maintained throughout the cemetery's entire history, leading to some doubt about which areas of the cemetery can be opened for new burials and where excavation should be avoided. For this reason, Grant Township commissioned a ground penetrating radar (GPR) survey of the cemetery, primarily to locate anomalies indicating possible unmarked graves and possible buried headstones. The survey …


An Investigation On Downwind Impacts Of The Keweenaw Peninsula On Lake-Effect Snow Events, Thomas M. Pavell Jan 2026

An Investigation On Downwind Impacts Of The Keweenaw Peninsula On Lake-Effect Snow Events, Thomas M. Pavell

Dissertations, Master's Theses and Master's Reports

Lake-effect snow (LES) produces copious amounts of snow across the Great Lakes region. While mechanisms and impacts are well-understood, they remain difficult to observe and study over Lake Superior and the Upper Peninsula of Michigan due to a large gap in radar coverage and sparse in-situ measurements. The goal of this project aimed to characterize variables present across Lake Superior and counties on and downstream of the Keweenaw Peninsula that contribute to the formation and evolution of lake-effect snowbands. Nine different lake-effect snow events were analyzed in this project, identifying structures and features resulting from upstream passage over the Keweenaw …


Reconciling Discretion With The Rule Of Law: A Rawlsian Analysis Of Civil Disobedience By State Actors In Liberal-Democratic Schemes, Reid Devoge Jan 2026

Reconciling Discretion With The Rule Of Law: A Rawlsian Analysis Of Civil Disobedience By State Actors In Liberal-Democratic Schemes, Reid Devoge

Dissertations, Master's Theses and Master's Reports

This dissertation starts from the position that the stability of liberal-democratic political schemes relies on its citizens mutually accepting a basic conception of political justice. While these conceptions of justice may vary, most incorporate the inter-connected concepts of autonomy, liberty, liberalism, and the rule of law. Within this conception of a liberal democracy, a potentially destabilizing issue arises when a legislatively passed law is put into effect, but a portion of the citizens perceive it as unjust. If legitimate (i.e., lawful) actions do not sufficiently resolve the concern, civil disobedience (i.e., disobeying the law) is a potential recourse, but this …


Beyond Satisfaction: Developing A Data Storytelling Evaluation Protocol For Stem Equity Program Assessment, Karen Colbert Jan 2026

Beyond Satisfaction: Developing A Data Storytelling Evaluation Protocol For Stem Equity Program Assessment, Karen Colbert

Dissertations, Master's Theses and Master's Reports

Higher education institutions routinely evaluate equity initiatives using measures of participation, engagement, and satisfaction. While these approaches provide useful information about program delivery, they offer limited insight into whether interventions change how participants understand institutional inequities. As a result, important dimensions of organizational learning and awareness often remain difficult to detect, particularly within STEM higher education environments where evaluation systems frequently emphasize measurable outputs over deeper indicators of change.

This dissertation examines how awareness-related outcomes can be identified, measured, and communicated within equity intervention contexts. Using a three-study design, the research first presents a systematic review of equity intervention evaluation …


An Engine, Not A Vessel: Place, Politics, And Health In The United States, Philip B. Rocco Jan 2026

An Engine, Not A Vessel: Place, Politics, And Health In The United States, Philip B. Rocco

Political Science Faculty Research and Publications

Social scientists often treat places as containers for social and economic phenomena that shape health outcomes. Yet this analytic practice conceals more than it reveals. Local governments in the United States should be understood as engines of both health promotion and stratification. As the contributions to this symposium suggest, governments not only occupy a formal place in the U.S. public health system, their decisions on everything from housing to transportation infrastructure can also have profound impacts on health outcomes. Local political economies likewise renegotiate the parameters of acceptable health interventions, public understandings of health disparities, and the status of population …


[Introduction To] Shakers At The Center : Manifesting Spirits & Spectacles In Nineteenth-Century America, Douglas L. Winiarski Jan 2026

[Introduction To] Shakers At The Center : Manifesting Spirits & Spectacles In Nineteenth-Century America, Douglas L. Winiarski

Bookshelf

Edited by Douglas WIniarski.

"Exploring the theological, social, and cultural dimensions of one of America’s most ambitious prophetic movements

The Shakers’ Era of Manifestations ranks among the most astounding events in American religious history. During the 1840s, members of the United Society of Believers in Christ’s Second Appearing embarked on an audacious project of receiving visions, revelations, and other manifestations from the spirit world and convincing both themselves and the world’s people of their reality. Gifted Shakers known as “instruments” surrendered their bodies to possessing spirits and celestial beings who, in turn, provided the Believers with an unimaginable number of …


Meat Is Dead, Melissa D. Mortazavi Jan 2026

Meat Is Dead, Melissa D. Mortazavi

Faculty Articles

The legal and cultural landscape surrounding meat in the United States is evolving as plant-based alternatives, GMO farm animals, and cell-cultivated meat move from test tube to table. While global demand for meat rises amid environmental, ethical, and resource challenges, cell-cultivated meat emerges as a scientifically viable alternative, offering identical nutritional value without the drawbacks of conventional livestock production. Despite federal regulatory approval from USDA and FDA, multiple states have enacted unusually restrictive laws—including bans— targeting cell-cultivated meat. These are motivated largely by economic protectionism, but also deeper cultural anxieties tied to tradition and identity. This Article argues that food …


Basis Design For Electronic Structure And Beyond, Weishi Wang Jan 2026

Basis Design For Electronic Structure And Beyond, Weishi Wang

Dartmouth College Ph.D Dissertations

At the intersection of quantum physics, quantum chemistry, and materials science, electronic structure is the study of electrons in solid-state and molecular systems. Electronic-structure computation relies on discretizing the many-electron Hamiltonian with a finite single-particle basis set. However, basis-set construction is conventionally treated as an ad hoc preprocessing step. This thesis develops an expressive and flexible framework for active, system-oriented basis-set design and numerical modeling strategies that treat basis functions as tunable representations to encode electronic ground-state information.

We first introduce a multi-layered, differentiable basis-construction framework that embeds a set of primitive parameters into mixed-contracted Gaussian-type orbitals. We then develop …


Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss Jan 2026

Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss

Dartmouth College Ph.D Dissertations

Magnetic particle spectroscopy (MPS) based aggregation assays rely on target induced changes in functionalized magnetic nanoparticle (fMNP) hydrodynamic diameter and/or changes in fMNP aggregation level to enable target detection. fMNP target binding can be modeled via Brownian and Néel relaxation. We are engineering an MPS-based aggregation assay to sense tumor necrosis factor (TNF)-⍺ in a 3D melanoma tissue culture to aid in the development of immunotherapies for cancer treatment. TNF-⍺ is an inflammatory cytokine, whose production can be linked to cell death.

The first part of this thesis investigates the effects of ligand density, off-target proteins, and salts on fMNP …


The Serotonin 1b Receptor In Psilocybin’S Therapeutic-Like Mechanisms: From Behavior To Network Reorganization, Sixtine Fleury Jan 2026

The Serotonin 1b Receptor In Psilocybin’S Therapeutic-Like Mechanisms: From Behavior To Network Reorganization, Sixtine Fleury

Dartmouth College Ph.D Dissertations

Mood disorders represent a substantial and growing global health crisis, with ~10 million adults in the US meeting criteria for a major depressive disorder (MDD). Current first-line treatments such as SSRIs require long-term daily administration and fail a significant proportion of patients, driving renewed interest in rapid-acting alternatives. Psilocybin, a serotonergic psychedelic, shows growing clinical evidence of efficacy in treating depressive and anxiety disorders, often producing therapeutic effects persisting weeks to months following a single dose. Yet, the neural mechanisms underlying these enduring effects remain poorly understood and have been largely attributed to the serotonin 2A receptor (5-HT2AR) based on …


Un Lugar A Donde No Puedo Volver: Perteneciendo En La Distancia, Alberto J. Alonso Jan 2026

Un Lugar A Donde No Puedo Volver: Perteneciendo En La Distancia, Alberto J. Alonso

Graduate Studies Theses and Dissertations 2026

“A Place I Cannot Return To: Distance and Belonging” investigates how home is not limited to a fixed place, but instead a reconstruction sustained through memory and longing, which focuses on personal experiences of being away from Puerto Rico. I contribute to this broader dialogue by offering a deeply personal perspective shaped by the complexities of cultural belonging. Through photography, collage, and painting, my art practice reconstructs fragmented visual narratives of lived experience to explore homesickness, nostalgia, and displacement, examining how personal and shared histories become anchors to what continually slips away. Although I can physically return to Puerto Rico, …


Rhetoric Of Opportunity: An Analysis Of Gullah Geechee Histories Through The Lens Of Counterstory, Xaria Arthur Jan 2026

Rhetoric Of Opportunity: An Analysis Of Gullah Geechee Histories Through The Lens Of Counterstory, Xaria Arthur

Graduate Studies Theses and Dissertations 2026

Counterstory as a method/ology has been used in a variety of disciplines to share experiences of individuals and communities whose voices have been historically silenced or suppressed. Utilizing this methodological framework, my study shares the stories of six Gullah Geechee descendants with ancestral roots in the unincorporated community of Nesmith in Williamsburg County, SC. Treating these minoritized and individual stories as experiential knowledge, I trace the counterstories as topoi to introduce and develop the theoretical concept that I call the rhetoric of opportunity, which refers to memories or stories that have come to motivate individuals toward or away from …


The Uncanny And Uneasy: An Exploration Into Using Puppets To Share Dark Stories, Grace Auls Jan 2026

The Uncanny And Uneasy: An Exploration Into Using Puppets To Share Dark Stories, Grace Auls

Graduate Studies Theses and Dissertations 2026

In this thesis, I will explore the role of puppetry and practical effects in evoking the uncanny and the uneasy as well as questioning the implications they have in dark theater and cinematic contexts. This paper will examine how puppetry and practical effects can contribute to potentially disturbing and dark imagery both on screen and in live theater. I will be focusing on looking at Jim Henson’s The Dark Crystal, as well as at different puppetry performances used in Voyage of the Little Mermaid (1992), Don’t Hug Me I’m Scared, Kirikou and the Sorceress (Kirikou et la Sorciere), and even …