Digital Commons Network^™

Small-World Simulations: A New Method To Test The Effect Of Legal Rules, Johannes Kruse

Coase-Sandor Institute for Law & Economics Research Paper Series

Small-world simulation exposes an artificial society to a legal rule and observes what its members do. The agents are driven by language models: their conduct is not stipulated in equations but reasoned in their own words. The architecture can be turned on any legal regime; personalized speed limits are the demonstration, chosen because rational-choice and behavioral predictions there conflict. Validated against documented driving patterns, the simulation generates behavior no one wrote into it. Because language models are trained on what people say rather than do, the method estimates orderings, not levels: a benchmark, not a substitute for evidence.

The Rise Of Global Collaboration In China Policy Research: Evidence From Bibliometric Network Analyses, 2000–2025, Yu Xiao, Aaron Ley, Ping Xu

Political Science Faculty Publications

This study examines the evolution of China policy research and its growing role in global policy scholarship. Using bibliometric and social network analyses of 326 articles published in 20 high-impact political science journals from 2000 to 2025, we trace the field’s expansion, identify key thematic concentrations, and document the emergence of robust international collaboration patterns. Cross-national co-authorship networks reveal a clear transition from a fragmented, Western-centered structure to a dual-hub system anchored by Mainland China and the United States, while institution-level networks show that leading Chinese universities have become central collaborators and Hong Kong institutions continue to serve as critical …

Characteristics Of Cerebral Palsy In The Midwestern Us, Susie Kim, Kelsey Steffen, Lauren Gottschalk-Henneberry, Jennifer Miros, Amy Robichaux-Viehoever, Karen Taca, Bhooma R Aravamuthan

2020-Current year OA Pubs

OBJECTIVE: Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.

METHODS: We integrated caregiver and clinician-facing standardized data entry into routine clinical care at a tertiary care CP center (https://bit.ly/CP-Intake-Methodology). We extracted this data for people with an ICD10 diagnosis of CP seen between March 22, 2023 and December 28, 2023 and used it to describe CP characteristics and determine factors affecting the …

Novel Insights Into Early Alzheimer's Disease: Quantitative Gradient Recalled Echo Mri Reveals Preatrophic Neuronal And Myelin Injury Concurrent With Emerging Amyloid Pathology, Satya V V N Kothapalli, Tammie L S Benzinger, Randall J Bateman, Melody Li, Cihat Eldeniz, John C Morris, Dmitriy A Yablonskiy

2020-Current year OA Pubs

BACKGROUND: Brain amyloid accumulation is considered an early sign of Alzheimer's disease (AD) pathology, appearing decades before manifestation of clinical symptoms. However, very little is known about neurodegeneration during this early AD stage. Herein we use quantitative gradient recalled echo (qGRE) magnetic resonance imaging (MRI) to reveal preatrophic microstructural neuronal and myelin damage concurrent with amyloid pathology.

METHODS: qGRE MRI and positron emission tomography (PET) amyloid [

RESULTS: qGRE detected significantly lower gray matter neuronal density and white matter myelination in the group of participants with amyloid level below the conventional amyloid-positive threshold (mean cortical standardized uptake value ratio of …

Biological Aging Acceleration In Major Depressive Disorder: A Multi-Omics Analysis, Breno Satler Diniz, Shangshu Zhao, Gabin Drouard, Eero Vuoksimaa, Miina Ollikainen, Eric J Lenze, Ming Xu, Richard H Fortinsky, George A Kuchel, Jaakko Kaprio, Chia-Ling Kuo

2020-Current year OA Pubs

Major depressive disorder (MDD) is linked to a higher risk of premature aging, but the mechanisms underlying this association remain unclear. Using data from two population cohorts (UK Biobank and Finnish Twin Cohort), we evaluate the relationship between systemic and organ-specific proteomic and epigenetic aging acceleration and MDD. A lifetime history of MDD was associated with accelerated proteomic aging at both systemic and organ-specific levels-including the brain-in both cohorts, with stronger associations than those observed with systemic epigenetic aging. Systemic and brain-specific proteomic aging acceleration were linked to higher risks of incident MDD and a greater risk of Alzheimer's disease, …

Alzheimer's Disease Stage 1 And 2: Biology, Diagnostics, And Treatment, Suzanne E. Schindler, Sarah M. Hartz, Et Al.

2020-Current year OA Pubs

No abstract provided.

Concordance Of Fluorescence In Situ Hybridization, Whole-Exome Sequencing, And Chromosomal Microarray For Evaluating High-Risk Molecular Features In Meningiomas, Brenndan Crumley, Emilie Russler-Germain, Sonika Dahiya

2020-Current year OA Pubs

BACKGROUND: Meningiomas are the most common primary intracranial tumors, classified into three WHO grades based on histologic and/or molecular criteria. cIMPACT-NOW Update 8 underscores the increasing importance of molecular testing in grading and risk stratification, noting that morphologically WHO grade 1 tumors with concurrent 1p and 22q losses demonstrate clinical behavior comparable to WHO grade 2 meningiomas. This study aimed to assess the concordance of fluorescence in situ hybridization (FISH), chromosomal microarray analysis (CMA), and whole-exome sequencing (WES) in defining the molecular risk profile of meningiomas.

METHODS: A total of 113 meningiomas were analyzed by WHO grade to assess the …

Library Support For Massive Open Online Courses (Moocs) In The Philippines: The Case Of American Corners, Princess Grace Wooden, Darin Jan Tindowen

Library Philosophy and Practice (e-journal)

This study examined the role of libraries in supporting Massive Open Online Courses (MOOCs) in the Philippines, with particular focus on American Corners as library-based learning spaces. Grounded in the increasing demand for flexible and accessible education, the study aimed to assess the readiness of American Corner libraries and determine the extent of MOOC implementation, as well as examine the relationship between these variables. A quantitative descriptive-correlational research design was employed, involving 28 American Corner staff composed of directors and librarians from 14 participating institutions. Data were collected using a validated survey questionnaire and analyzed through frequency, percentage, weighted mean, …

Uncovering The Disciplinary Pulse Of Library And Information Science Through Large-Scale Topic Modelling Of Openalex Scholarly Literature, Sailendra Malik, Sukumar Mandal

Library Philosophy and Practice (e-journal)

Library and Information Science is among the oldest and intellectually pluralistic scholarly disciplines but the inner thematic structure has not been established. The article develops a systematic and data intensive mapping of the field by the Latent Dirichlet Allocation topic modelling to 7,824 articles in the English language indexed in OpenAlex in the year 2000 to 2025. A ten topic solution is an optimised solution that identifies a group of readable and sensible thematic domains including information literacy digital libraries scientometrics archives and scholarly communication. The analysis of temporal trajectory reveals that there have been consistent expansion at the emergent …

Rethinking Library Opac: From Siloed Retrieval To Ai And Ml-Driven Discovery Using Fastapi And Mysql, Sukumar Mandal

Library Philosophy and Practice (e-journal)

The paper explores integration methods between MySQL and FastAPI to develop dynamic Online Public Access Catalog services including functionalities for modern libraries and information centers. It addresses evolving user expectations by replacing rigid keyword-based search models with adaptive, intelligent discovery experiences that prioritize search relevance. The goal involves transforming traditional library retrieval tools into contextual discovery platforms that effectively understand specific user intent and complex needs. The prototype was created on Ubuntu in a customized Python environment. It uses FastAPI to manage asynchronous API calls and MySQL to store bibliographic data. SQLAlchemy abstracts the database layer, and Pydantic validates data. …

Availability And Utilization Of School Library Resources And Its Impacts On The Academic Excellence Of Secondary School Students In Edo State., Iyobosa Ewere Mrs., Ben Asuquo, Glory Mbah Mrs.

Library Philosophy and Practice (e-journal)

The study examines availability, and utilization of school library resources and its impacts on the academic excellence in secondary school libraries in Edo state. The descriptive survey research was adopted for the study. The population of the study was 2162 senior secondary school students from Idia Girls’ College, Boiling Point Academy and UNIBEN Demonstration Secondary School. The sampling techniques used for the study was Random Sampling Technique, a total of 216 respondents was used as the sample size representing 10% of the total population. A well structured questionnaire was designed and distributed to respondents .A total of 216 copies of …

From Digital Skills To Digital Ventures: Exploring The Influence Of Digital Competence On Infopreneurship Intentions Of Library And Information Science Students In Nigerian Polytechnics, Uwaebuka Wisdom Madu Dr., Stephen Adekunle Ajayi Dr

Library Philosophy and Practice (e-journal)

The focus of this study was to investigate the influence of digital competence on infopreneurship intention among Library and Information Science (LIS) students in federal polytechnics in South-West Nigeria, a context characterized by high graduate unemployment and rapid digital transformation. Guided by the Theory of Planned Behaviour and Eshet-Alkalai's Digital Literacy Model, a descriptive survey design was employed. The population comprised 638 final-year LIS students across four federal polytechnics, with a sample of 468 selected through multi-stage sampling. A validated questionnaire with a reliability coefficient of 0.828 was used for data collection. 388 responses amounting to 82.9% response rate was …

Smallholder Farmers' Willingness To Pay For The Farmbetter Mobile App-Based Agricultural Extension: Evidence From A Bdm Experiment In Tanzania And Burkina Faso, Cool Dady Mangole, Kelvin Mulungu, Christian Kamala Kaghoma, Maurice Tschopp, Menale Kassie

All Peer-Reviewed Publications

Financial contributions from farmers are increasingly acknowledged as a sustainable mechanism for funding extension services. However, the literature on willingness to pay (WTP) for digital agricultural extension is limited. Conducting a thorough assessment of WTP for digital extension is critical for designing effective pricing policies and ensuring financial sustainability. This study examines the WTP for a novel digital extension platform named farmbetter, leveraging primary data collected in Tanzania and Burkina Faso. The Becker-DeGroot-Marschak (BDM) experiment was used to elicit the amount farmers are willing to pay. We applied the Lasso machine learning to predict the relevant drivers of WTP and …

Roles Of Cytokines In Modulating Trypanosoma Brucei Rhodesiense Infection Outcomes In Vervet Monkeys, Clarah Jebet, John Kibuthu Thuita, Daniel Masiga, Benedict Owino Orindi, John Oidho, Mark C. Field, Enock Matovu, Vincent Owino Adung’A

All Peer-Reviewed Publications

Introduction:

Human African trypanosomiasis (HAT), caused by Trypanosoma brucei rhodesiense, is categorized as acute due to rapid disease progression but presents varying clinical outcomes. Although the mechanisms underpinning differential clinical progression are poorly understood, both host and parasite factors are implicated. Therefore, we sought to elucidate roles of primate host factors in mediating varying T. b. rhodesiense infection outcomes.

Methods:

Here, we assessed the roles of selected host cytokines in disease progression using a tsetse-mediated infection in a non-human primate (NHP) vervet monkey model that closely mimics HAT and natural infection. We quantified eight cytokines, including TNF-α, IFN-γ, IL-10, IL-6, …

Pathways, Outputs And Impact Of Nih-Supported Bioinformatics And Genomics Graduate Trainees In Africa, Daudi Jjingo, Andrew Walakira, Suhaila Hashim, Cisse Cheickna, Ronald Galiwango, Caleb Kibet, Florence N. Kivunike, Gerald Mboowa, Fredrick Elishama Kakembo, Babajide Ayodele, Jean Baka Domelevo Entfellner, Santie De Villiers, Karen Wambui, Segun Fatumo, Tinashe Chikowore, John Mukisa, Alfred Ssekagiri, Nicholas Bbosa, Julius Mulindwa, Samuel Kyobe, Mike Nsubuga, Grace Kebirungi, Eric Katagirya, Savannah Mwesigwa, Ibra Lujumba, Rogers Kamulegeya, Samuel Kirimunda, Stephen Kanyerezi, Shahiid Kiyaga, Ivan Sserwadda, Davis Kiberu, Daniel Masiga

All Peer-Reviewed Publications

Global biomedical and health research is increasingly relying on genomic and computational approaches, largely driven by the increasing volumes of nucleic acid sequencing. Concurrently, epidemiological studies and clinical records are generating enormous amounts of data amenable to disease modeling, machine learning, and artificial intelligence techniques. Bioinformatics and data science expertise is therefore essential for improved population health. Accordingly, in 2012, the US National Institutes of Health (NIH) in partnership with the Wellcome Trust, and with support from the African Society for Human Genetics, initiated the H3Africa (Human Heredity and Health in Africa) consortium. One of its key goals was to …

Impact Of Environmental Microparticles On Insect Olfaction, Steve B.S. Baleba, Danube K.N. Wandji, Yves H. Tchiechoua, Komi Mensah Agboka, Iman B. Hassaballa, Victor O. Omondi, Beatrice T. Nganso, Saliou Niassy, Souleymane Diallo, Merid N. Getahun

All Peer-Reviewed Publications

Terrestrial insects underpin key ecosystem services, including pollination, herbivory regulation, decomposition, nutrient cycling, and disease control. These functions depend on chemical communication that guides insects to food, mates, hosts, shelters, and oviposition sites while helping them avoid threats. Environmental microparticles, such as micro- and nanoplastics, tyre wear particles, soot, mineral dust, and agricultural residues, are now widespread across air, soil, vegetation, and indoor environments, exposing insects through contact, deposition, and ingestion. Growing evidence shows that these particles disrupt insect olfaction by adsorbing volatile compounds, blocking antennal sensilla, and interfering with receptor and neuronal processes. These disruptions impair foraging, mating, oviposition, …

Impacts Of Multitrophic Interactions In Diversified Cropping Systems For Sustainable Management Of Spodoptera Frugiperda, Abdul A. Jalloh, Abdullahi Ahmed Yusuf, Fathiya M. Khamis, Subramanian Sevgan, Daniel Munyao Mutyambai

All Peer-Reviewed Publications

Background: Rapid population growth has made the sustainable intensification of agricultural productivity essential for meeting global food demands while maintaining environmental integrity and biodiversity. Diversified cropping systems, such as intercropping, push-pull systems, and cover cropping, are recognized as agroecological strategies to enhance plant growth and protection, and suppress major pests, including the fall armyworm (FAW, Spodoptera frugiperda). These systems influence complex above-and-below ground interactions among herbivorous pests, plants, soil microbes, and their natural enemies. Aims: This review synthesizes current knowledge on how diversified cropping systems shape multitrophic interactions that affect soil health, plant performance, S. frugiperda suppression, and biocontrol within …

Symbolism And Choreographic Practice: Exploring The Application Of Symbolism To Dance Through The Creation Of A Solo Choreographic Work, Ruby Brazzalotto

Theses : Honours

This research project explored the significance of symbolism as a communicative tool within dance theatre. The project drew upon Symbolist theory and Pina Bausch’s choreographic approaches, in an attempt to understand how the symbolic use of props and gestural movement can communicate and elevate meaning within dance performance. This project involved the creation of a new solo dance work, self-reflexivity, and analysis of how Bausch’s and Symbolists’ modes of presenting ideas overlap. The project sought to document how symbolic props can be chosen, developed and combined with theatrical choreography to convey meaning to audiences.

Directing Young Actors, Mitchell Whelan

Theses : Honours

This reflective practice case study examines the studio environment of a small ensemble of female actors aged 16-19, in the rehearsal of a one-act play. Performing arts researchers working in youth spaces commonly adhere to conventions of ethnodrama and facilitate a process in which participants contribute personal stories as performance material. The present paper uses a published text (Slut by Patricia Cornelius) to position participants as actors, rather than devisors who must conjure original material. Through critical reflection, the project assesses the impact of developing performance material slowly while also making time for socialisation between castmates. Drawing on my repertoire …

Waterborne, Theresa Ann Wilks

Theses : Honours

Waterborne incorporates four eco-Gothic fiction narratives that, through a practice-led enquiry, examine how drawing upon the abject, by employing the Gothic tropes of violence and captivity within Australian settings, may be positioned to foreground environmental impacts from anthropocentrism, particularly upon bodies of water. Utilising eco-Gothic settings in water locations exhibiting ecological damage, from land clearing and water management practices, the fictional narratives may also highlight the physical, social and emotional impacts of adverse environmental change upon ourselves.

“High Tea and Acquisitions” followed time immersed at a freshwater lake that is choked with introduced weeds and becoming shallow with sediment. It …