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2026

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Synergistic Effect Of Different Ions And Hexadecyltrimethylammonium Bromide On Wettability Alteration For Carbonate Rock, Rafal S. Abdullah, Hussein Q. Hussein, Rana R. Jali Feb 2026

Synergistic Effect Of Different Ions And Hexadecyltrimethylammonium Bromide On Wettability Alteration For Carbonate Rock, Rafal S. Abdullah, Hussein Q. Hussein, Rana R. Jali

Baghdad Science Journal

Naturally carbonate reservoirs have very low oil recovery efficiency owing to their wettability and tightness of matrix. However, adding surfactant to brine solution can enhance oil recovery by changing the wettability of the carbonate rock surface from oil-wet to water-wet. In the present study, the effects of different brines in the presence of surfactant hexadecyltrimethylammonium bromide (CTAB), on the wettability of carbonate rock were investigated through different characteristics such as surface tension interfacial tension and contact angle. The best concentration of CTAB was investigated at 500 ppm in brine (NaCl) reduced surface tension and interfacial tensions to 42 mN/m and …


The Impact Of Vascular Endothelial Growth Factor, Neutrophil Gelatinase-Associated Lipocalin, And Interleukin-38 Food And Air Allergy Patients Following The Pandemic Of Covid-19 In Iraq, Esraa Hameed Khamees, Zaizafoon N. Nasif Feb 2026

The Impact Of Vascular Endothelial Growth Factor, Neutrophil Gelatinase-Associated Lipocalin, And Interleukin-38 Food And Air Allergy Patients Following The Pandemic Of Covid-19 In Iraq, Esraa Hameed Khamees, Zaizafoon N. Nasif

Baghdad Science Journal

Allergies are a common health issue where the immune system reacts to substances in the environment that are normally harmless. This study further investigates the effects of vascular endothelial growth factor (VEGF), neutrophil gelatinase-associated lipocalin (NGAL), interleukin-38 (IL-38), immunoglobulin E (IgE), and the neutrophil-lymphocyte ratio (NLR) in these individuals, offering insight into the probable processes behind allergic responses following the pandemic. The study comprised 120 non-vaccinated females with previous COVID-19 infection. Groups included controls and food and air (F&A) allergic patients, with 60 individuals matched for age and gender. Serum levels of IL-38, VEGF, IgE, and NGLA were assessed using …


Cerebral Hypoperfusion Causes Behavioral Changes And Impairs The Rod Photoreceptor Pathway In The Retina Of Aged Mice, Spencer Talmage Barney, Daniela Becerril, Sheelu Monga, Samantha Flores, Audrey Lee, Marlon Fraga Mattos, Ross M Perez, Frank W Blixt, Michael Maniskas, Shuning Huang, Hongyu Wu, Chunfeng Tan, Louise D Mccullough, Elizabeth Zuniga-Sanchez, Jose Felix Moruno-Manchon Feb 2026

Cerebral Hypoperfusion Causes Behavioral Changes And Impairs The Rod Photoreceptor Pathway In The Retina Of Aged Mice, Spencer Talmage Barney, Daniela Becerril, Sheelu Monga, Samantha Flores, Audrey Lee, Marlon Fraga Mattos, Ross M Perez, Frank W Blixt, Michael Maniskas, Shuning Huang, Hongyu Wu, Chunfeng Tan, Louise D Mccullough, Elizabeth Zuniga-Sanchez, Jose Felix Moruno-Manchon

Faculty, Staff and Student Publications

Gradual reduction of cerebral blood flow occurs with aging, and it is a major cause of vascular dementia, a group of dementias with a cerebrovascular component. Interestingly, patients who have suffered a vascular insult may develop retinopathy, which may occur as an early symptom of vascular dementia. Several rodent models using young animals have been generated to mimic retinopathy caused by cerebral hypoperfusion; however, given that aging is an important factor in developing vascular dementia and hypoperfusion retinopathy, we propose to use aged (17-month-old) mice in a model of cerebral hypoperfusion. In this model, we implant two metallic micro-coils (0.16 …


Preparation, Characterization, And Antimicrobial Evaluation Of A Cefepime Derivative With Divalent Transition Metals, Zahraa A. Jaber, Israa H. Ibraheem, Sahar S. Hassan Feb 2026

Preparation, Characterization, And Antimicrobial Evaluation Of A Cefepime Derivative With Divalent Transition Metals, Zahraa A. Jaber, Israa H. Ibraheem, Sahar S. Hassan

Baghdad Science Journal

The Schiff base ligand (L)- 1-((7-((Z), was recently synthesized 2–(2-((Z)–5,5-diethyl2-(methoxyimino)acetamido)-2-(methoxycarbonyl)-2,6-dioxotetrahydropyrimidin-4(1H)-ylideneamino) thiazol-4-yl8-oxo-5-thia , the next mineral ions, Ni2+, Cu2+, Zn2+, and Co2+, are permitted to react with 1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidinium, leading to the formation of new metal complexes with distinct geometric shapes. By detecting the shifting in the azomethines band and the appearance of M-N and M-O bands, FT-IR confirmed the occurrence of coordination through N of azobenzene and two O atoms of beta lactam and ester, indicating the development of Schiff base complexes as well as the original Schiff base. Additionally, we can use …


Determination Of Mebeverine – Hcl Using 3, 5–Dinitrosalicylic Acid And Multiple Continuous Flow Cell That Works As A Solo Flow Cell With 4s×3 – 3d Analyzer, Elham N. Mezaal, Nagam S. Turkey Feb 2026

Determination Of Mebeverine – Hcl Using 3, 5–Dinitrosalicylic Acid And Multiple Continuous Flow Cell That Works As A Solo Flow Cell With 4s×3 – 3d Analyzer, Elham N. Mezaal, Nagam S. Turkey

Baghdad Science Journal

A new method, simple and sensitive was utilized in determining mebeverine – HCl (MB-HCl) (3, 4-Dimethoxy benzoic acid ethyl 2, 4 methoxy4-phenyl-1-methyl ethyl amino-butyl ester) in pure and pharmaceutical formulations via utilization this multiple continuous flow cell. The method is dependent on genesis for complex of ion pair(4-((3, 4-dimethoxybenzoyl) oxy)-N-ethyl-N-(1-(4-methoxyphenyl) propan-2-yl) butan-1-aminium-2-hydroxy-3,5-dinitrobenzoate) among mebeverine–HCl (MB-HCl) and 3,5-Dinitrosalicylic acid (3,5-DNSA) in ammonium acetate middle to configure a whiteish yellow precipitate compound via utilizing multiple continuous flow cell that works as a solo flow cell with 4S×3 – 3D analyzer. Optimum parameters were studied to raise the sensitivity for improving the method. …


Leveraging Best Practice Initiatives To Develop An Innovative And Proactive Approach To Stress Management, Shannon Cronin Patel, John Hunt, Mary Law Feb 2026

Leveraging Best Practice Initiatives To Develop An Innovative And Proactive Approach To Stress Management, Shannon Cronin Patel, John Hunt, Mary Law

Creating Healthy Work Environments (CHWE)

Background: A 2023 Premiere Inc. survey reported that greater than 40% of US healthcare professionals have experienced at least one episode of workplace violence during the past two years. Confounding issues position healthcare professionals at increased risk for experiencing daily stress inducing situations including but not limited to: staffing related deficiencies, increased incidences of workplace violence, and increased risk for secondary victim incidents that perpetuate wounded healers. Despite increases in stress inducing situations, current stress mitigating interventions remain reactive, antiquated, and fail to meet the emotional needs of healthcare professionals. Current stress and critical incident management models provide reactive support …


The Rider (2026-02-23), Daniela Chapa-Reyes Feb 2026

The Rider (2026-02-23), Daniela Chapa-Reyes

The Rider Archives

Vol. 11, No. 20


Innovative Approaches For Lung Cancer Screening And Interception, Jianjun Zhang, Matthew D Park, Tej Pandya, Elaine Shum, Jia Wu, Simon Heeke, Ramin Salehi-Rad, Thomas U Marron, Zhubo Wei, Hui Li, Torsten G Blum, John V Heymach, Steven M Dubinett, Pan-Chyr Yang, Charles Swanton, Miriam Merad Feb 2026

Innovative Approaches For Lung Cancer Screening And Interception, Jianjun Zhang, Matthew D Park, Tej Pandya, Elaine Shum, Jia Wu, Simon Heeke, Ramin Salehi-Rad, Thomas U Marron, Zhubo Wei, Hui Li, Torsten G Blum, John V Heymach, Steven M Dubinett, Pan-Chyr Yang, Charles Swanton, Miriam Merad

Faculty, Staff and Student Publications

Lung cancer remains the leading cause of cancer-related deaths worldwide, partly because many patients are diagnosed at late stages, highlighting the urgent need for effective early detection and intervention strategies. Low-dose computed tomography (LDCT)-based screening reduces lung cancer mortality in high-risk populations defined by age and smoking history; however, the uptake of LDCT remains low among eligible individuals. Compounding this issue, modelling studies estimate that nearly half of lung cancers occur in individuals who do not meet eligibility criteria for LDCT-based lung cancer screening under current guidelines. Moreover, LDCT-based screening has inherent limitations, including a high rate of false-positive results …


Synthesis, Characterization And Photodegradation Study Of Titanium Dioxide Nanoparticles Mediated Using Melon Peel Extract, Mohamed Abdelkalik Hussain, Wadhah Naji Al Sieadi Feb 2026

Synthesis, Characterization And Photodegradation Study Of Titanium Dioxide Nanoparticles Mediated Using Melon Peel Extract, Mohamed Abdelkalik Hussain, Wadhah Naji Al Sieadi

Baghdad Science Journal

The importance of nanotechnology in protecting the environment is represented in multiple applications, including, for example, the green synthesis of nanoparticles (NPs), using the remains of plant parts, as well as photolysis application that used semiconductors NPs which showed a clear effect in treating water from organic pollutants, this study combines these two applications, in terms of green synthesis of titanium dioxide nanoparticles (TiO2NPs) using melon peel (Cucumis melo L.) in sol-gel method, as well as, the photodegradation of methylene blue dye (MB) by using a new irradiation photoreactor device which has designed and implemented for …


Synthesis, Spectroscopic Characterization, And Photostability Studies Of A New Ligand Derivative Of 4-Bromobenzaldehyde And Its Metal Complexes, Enass J. Waheed, Ali Mudher Abdulkareem, Ibtisam Khalifa Jassim Feb 2026

Synthesis, Spectroscopic Characterization, And Photostability Studies Of A New Ligand Derivative Of 4-Bromobenzaldehyde And Its Metal Complexes, Enass J. Waheed, Ali Mudher Abdulkareem, Ibtisam Khalifa Jassim

Baghdad Science Journal

The new Schiff base ligand (LB) was synthesized by reacting precursor (P) with 4-bromobenzaldehyde. This ligand formed three new complexes: [Pd(LB)(H2O)2]Cl2 (square planar) and [M(LB)(H2O)2Cl2].mCl2 (octahedral), where m=0 for Co+2 and 1 for Pt+4, upon reaction with the respective metal ions. Characterization of the ligand (LB) and its metal complexes involved various techniques including 1H- and 13C-NMR, FT-IR, UV-Vis spectroscopy, magnetic susceptibility measurements, CHNS analysis, and molar conductivity. The photo-stabilization of polymers aims to mitigate …


Investigating Interleukin-19 And Interleukin-33 In Breast Cancer Of Iraqi Women: An Immunohistochemical Study, Fouad Najm Abed, Suhad Saad Mahmood Feb 2026

Investigating Interleukin-19 And Interleukin-33 In Breast Cancer Of Iraqi Women: An Immunohistochemical Study, Fouad Najm Abed, Suhad Saad Mahmood

Baghdad Science Journal

Cytokines are immune elements that have been found as marker either for tumor-promoting or inhibiting effects on breast tumor development, depending evidently on their exact quantities as well as the existence of additional modifying variables. The study aims to evaluate the relationship between breast cancer tissue and the expression level of IL-19 and IL-33. This study includes using breast cancer tissue (30 specimens) and normal breast tissue (20 specimens) to analyze the expression level of IL-19 and IL-30. Using immunohistochemical technique, the results indicated that lL-33 and also IL-19 were strongly elevated in patients with stage II and stage III …


In Silico Study Of N-Pyrazoline Derivate Compounds As Anticancer Through Inhibition Of Pi3k And Pr Expression, Denny Satria, Syukur Berkat Waruwu, Eti Nurwening Sholikhah, Mustofa Mustofa, Pamungkas Bagus Satriyo, Tutik Dwi Wahyuningsih, Hesti L Wiraswati, Ema Damayanti Feb 2026

In Silico Study Of N-Pyrazoline Derivate Compounds As Anticancer Through Inhibition Of Pi3k And Pr Expression, Denny Satria, Syukur Berkat Waruwu, Eti Nurwening Sholikhah, Mustofa Mustofa, Pamungkas Bagus Satriyo, Tutik Dwi Wahyuningsih, Hesti L Wiraswati, Ema Damayanti

Baghdad Science Journal

Breast cancer treatment has many options directed at therapeutic targets, but some remain incurable, so new therapies are needed. Pyrazoline has shown various biological activities, one of which is anticancer effectiveness. The purpose of this study was to conduct an in silico analysis of Pyrazoline inhibition of PI3K and PR proteins using docking and MD simulation methods. Predictions of toxicity and pharmacokinetics, including absorption, distribution, metabolism, excretion, and toxicity, were also conducted computationally. The analysis showed that the Pyrazoline compound had interactions with ligands of PI3K proteins and PR proteins. Pharmacokinetic predictions showed that the compound in the human intestine …


Synthesis, Characterization, And Anticancer Activity Study Of New Curcumin Analogues Against Mda-Mb 231 Breast Cancer Cell Line, Ola A. Odah, Rita S Elias, Shaker A. N. Al-Jadaan Feb 2026

Synthesis, Characterization, And Anticancer Activity Study Of New Curcumin Analogues Against Mda-Mb 231 Breast Cancer Cell Line, Ola A. Odah, Rita S Elias, Shaker A. N. Al-Jadaan

Baghdad Science Journal

Synthesis of six new curcumin analogues was performed through condensation reaction of 3-methyl-2, 4-pentandione with substituted aromatic aldehyde derivatives and boron oxide in the presence of trimethylborate and butylamine. The reaction was carried out under ultrasonic irradiation. The synthesized compounds were identified using 1H-, 13C-NMR, FT-IR spectroscopy, and electron impact mass spectrometry. The Swiss ADME website was used to predict the physicochemical properties of the new compounds using computational techniques like ADME studies. All produced compounds, according to this study, complies with the Lipinski rule of five. The microculture tetrazolium (MTT) assay was utilized to assess the investigated …


A New Prospective Of Colistin Resistance Profile Of Some Staphylococcus Species Isolated From Iraqi Wound Fractured Foot, Zahraa M. Fadhil, Halah H Al-Haideri Feb 2026

A New Prospective Of Colistin Resistance Profile Of Some Staphylococcus Species Isolated From Iraqi Wound Fractured Foot, Zahraa M. Fadhil, Halah H Al-Haideri

Baghdad Science Journal

Sulbactam belongs to β-lactamase inhibitors that are more commonly used for Gram-negative bacteria than Gram-positive bacteria. In this study, nine different species of Staphylococcus (S. aureus, S. epidermidis, S.hominis, S. lentus, S. pseudintermedius, S. lugdunensis, S. haemolyticus, S. sciuri , and S. warneri. were isolated from wounded-fractured feet of Iraqi patients. The spectrum of activity of sulbactam and colistin against all isolates was evaluated. Surprisingly, among S. aureus isolates, 5 (12) isolates were sensitive to colistin, whereas, all bacterial isolates were completely resistant to sulbactam. Here, our study revealed that combining …


Assessment Of Histopathological Features Of The Placenta And Plasma Level Of Βhcg, Estrogen, And Progesterone In First-Trimester Spontaneous Miscarriage, Russul Hameed Hassan, Mukhtar K. Haba Feb 2026

Assessment Of Histopathological Features Of The Placenta And Plasma Level Of Βhcg, Estrogen, And Progesterone In First-Trimester Spontaneous Miscarriage, Russul Hameed Hassan, Mukhtar K. Haba

Baghdad Science Journal

Miscarriage is a distressing complication with many fetal and maternal abnormalities. About 15% of pregnancies end in spontaneous miscarriages, and over 80% of these occur in the first 12 weeks of gestation. This research aims to evaluate the changes in the hormonal status in addition to determining the types and incidences of abnormalities in the decidua and chorionic villi of placentas that have been aborted. The peripheral blood samples were collected from twenty normal pregnant women as a control group and 30 aborted women. The obstetric characteristics results showed that the patients' mean maternal age was 25.73 ± 7.32 years …


Relatively Prime Detour Domination Number Of Switching Certain Special Graphs, C. Jayasekaran, L. G. Binoja Feb 2026

Relatively Prime Detour Domination Number Of Switching Certain Special Graphs, C. Jayasekaran, L. G. Binoja

Baghdad Science Journal

A set S ⊆ V is said to be a relatively prime detour dominating set of a graph G if it has at least two members is a detour set and a dominating set for any pair of vertices b and w such that (deg(b), deg(w)) = 1. The lowest cardinality of a relatively prime detour dominating set is indicated by γrpdn (G) and defines the lowest cardinality of a relatively prime detour dominating set of order γrpdn (G) said to as a γrpdn-set of G. If there is no relatively prime detour dominating set, the …


The George-Anne Daily, Georgia Southern University Feb 2026

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Supt16h-Associated Neurodevelopmental Disorder And Neurocristopathy: Genetic And Phenotypic Spectrum, Eunhye Lee, Seungmin Sim, Hee-Jung Choi, Eugene Y Liang, Carolyn Le, Roya Bina, Ryan Cohen, Elizabeth George, Soo Yeon Kim, Gifty Bhat, Erin Falsey, Richard Sidlow, Kristin Clinard, Shay Ben-Shachar, Eleina England, Beatriz Menendez, Isabella Herman, Shelly Nielsen, Jaya Punetha, Priya Bhola, J Austin Hamm, Megan A Keeney, Nike Sitzman, Sara Berger, Lakshmi Mehta, Alison J Conn, Lilian Downie, Myla Ashfaq, Hope Northrup, Ange-Line Bruel, Sylvie Odent, Justin O Szot, Noelia Nunez Martinez, Sunju Park, Julie Refkin, Jean-Marc Good, Fabienne Maurer, Cédric Le Caignec, David J Coman, Erin Anderson, Linda J Richards, Ryan J Dean, Caleb Yang, Chulwon Choi, Byung Joon Hwang, Jin Sook Lee, William B Dobyns, Murim Choi, Elliott H Sherr, Jong-Hee Chae, Yun Kee, Emanuela Argilli Feb 2026

Supt16h-Associated Neurodevelopmental Disorder And Neurocristopathy: Genetic And Phenotypic Spectrum, Eunhye Lee, Seungmin Sim, Hee-Jung Choi, Eugene Y Liang, Carolyn Le, Roya Bina, Ryan Cohen, Elizabeth George, Soo Yeon Kim, Gifty Bhat, Erin Falsey, Richard Sidlow, Kristin Clinard, Shay Ben-Shachar, Eleina England, Beatriz Menendez, Isabella Herman, Shelly Nielsen, Jaya Punetha, Priya Bhola, J Austin Hamm, Megan A Keeney, Nike Sitzman, Sara Berger, Lakshmi Mehta, Alison J Conn, Lilian Downie, Myla Ashfaq, Hope Northrup, Ange-Line Bruel, Sylvie Odent, Justin O Szot, Noelia Nunez Martinez, Sunju Park, Julie Refkin, Jean-Marc Good, Fabienne Maurer, Cédric Le Caignec, David J Coman, Erin Anderson, Linda J Richards, Ryan J Dean, Caleb Yang, Chulwon Choi, Byung Joon Hwang, Jin Sook Lee, William B Dobyns, Murim Choi, Elliott H Sherr, Jong-Hee Chae, Yun Kee, Emanuela Argilli

Faculty, Staff and Student Publications

SUPT16H encodes a subunit of the FACT (FAcilitates Chromatin Transcription) complex, a histone chaperone essential for maintaining chromatin integrity during transcription, replication, and DNA repair. Pathogenic de novo SUPT16H missense variants have previously been linked to neurodevelopmental disorders in eight individuals. Here, we expand the genotypic and phenotypic spectrum by identifying 24 additional individuals harboring ultrarare heterozygous missense or truncating variants, who share overlapping clinical features including intellectual disability, autism spectrum disorder, hypotonia, and characteristic craniofacial dysmorphism. To elucidate the underlying mechanisms, we generated a supt16h knockout zebrafish model using CRISPR/Cas9. The supt16h loss-of-function (LOF) model recapitulated key patient phenotypes …


Role Of Developmental Plasticity In Tethered Flight Performance Of The Oriental Fruit Fly, Bactrocera Dorsalis (Hendel) (Diptera: Tephritidae), Thabang P. Moropa, Steve B.S. Baleba, Christopher W. Weldon Feb 2026

Role Of Developmental Plasticity In Tethered Flight Performance Of The Oriental Fruit Fly, Bactrocera Dorsalis (Hendel) (Diptera: Tephritidae), Thabang P. Moropa, Steve B.S. Baleba, Christopher W. Weldon

All Peer-Reviewed Publications

This study investigated the effect of nutrition on development of wings and adult body condition of Bactrocera dorsalis (Hendel), an exotic pest of Asian origin and a species of economic importance in South Africa. Six host fruit types were used to rear B. dorsalis: mango, guava, orange, grapefruit, papaya and apple. One day after emergence, adults were used for tethered flight assessments using computerised flight mills. Additional flies were assessed in terms of wing morphology using geometric morphometrics, flight muscle mass, and lipid content. There were significant differences in the larval and pupal developmental time as well as larval and …


From The Tropics To The Poles: Chemical Investigation Of Marine Invertebrates Through Elucidation And Synthesis, Benjamin Reed Smith Feb 2026

From The Tropics To The Poles: Chemical Investigation Of Marine Invertebrates Through Elucidation And Synthesis, Benjamin Reed Smith

USF Tampa Graduate Theses and Dissertations

Society’s perpetual need for new disease treatments continuously leans on the shouldersof willing researchers. Even in modern day, many described diseases lack a cure or a symptomatic treatment; worse yet, the necessity for new drugs is amplified with rises in drug- resistant microbial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Historically, remedies and disease treatments have been rooted in the medicinal properties of plants and animals; naturally derived analgesics, like milk of the poppy or willow bark tea, date back thousands of years. With the developments of modern medicine, drug discovery, and natural product researchers found a wealth of potential …


Role Of Piezo1 Channels Expressed In Pvn In Regulating Sympathetic Nerve Activity And Arterial Blood Pressure In Rats, Yue Chen, Wei Guo, Jichun Wang, Min Wang, Yuying Yang, Gregory Miodonski, Enshe Jiang, Qing Hui Chen, Yi Yang, Renjun Wang Feb 2026

Role Of Piezo1 Channels Expressed In Pvn In Regulating Sympathetic Nerve Activity And Arterial Blood Pressure In Rats, Yue Chen, Wei Guo, Jichun Wang, Min Wang, Yuying Yang, Gregory Miodonski, Enshe Jiang, Qing Hui Chen, Yi Yang, Renjun Wang

Michigan Tech Publications

Mechanosensitive Piezo1 channels participate in regulating pain sensitivity, insulin secretion, and vascular tension; however, their expression in the autonomic paraventricular nucleus (PVN) and role in modulating sympathetic outflow and cardiovascular function remain unstudied. In this study, unilateral PVN microinjection of the Piezo1 channel blocker Dooku1 (0.1, 1, 10, 100, and 200 pmol) administered to anesthetized male rats increased renal sympathetic nerve activity (RSNA) and mean artery pressure (MAP) in a dose-dependent manner, with maximum increases of 93 ± 30% (p < 0.0001) and 21 ± 5 mmHg (p < 0.0001), respectively, elicited by Dooku1 at 100 pmol. Similarly, PVN microinjection of the peptide Piezo1 channel blocker GsMTx4 (1 nmol) significantly increased RSNA (p < 0.001) and MAP (p < 0.0001). Conversely, PVN-microinjected Piezo1 channel activators Yoda1 (5 nmol) and Jedi2 (5 nmol) did not significantly alter RSNA or MAP. Western blot and qRT-PCR analyses of the hypothalamic PVN showed abundant Piezo1 mRNA and protein expression. Immunofluorescence detection showed that Piezo1 was expressed in pre-sympathetic PVN neurons with axons projecting to the rostral ventrolateral medulla. We conclude that Piezo1 channels expressed in the autonomic PVN neurons play an important role in regulating sympathetic outflow and cardiovascular function.


دور الرسوم المتحركة في تعزيز فاعلية تصميم الإنفوجرافيك, Hussein Mohammad Al-Omari Feb 2026

دور الرسوم المتحركة في تعزيز فاعلية تصميم الإنفوجرافيك, Hussein Mohammad Al-Omari

Middle East Journal of Communication Studies

An infographic's primary objective is to satisfy the demands and expectations of its audience by presenting information in a logical and intelligible way. Recent developments in graphic design techniques have made several intricate techniques approachable by artists and designers, elevating the design process to a sophisticated profession that transcends media boundaries. Static infographics and animated infographics feature the same material; however, animated infographics have the benefit of displaying information via continuous motion and animated sequences rather than in static components or separate stages, and that’s because of the special features of animation, which attract a wider audience. They are also …


The Role Of Motion Graphics In Enhancing The Effectiveness Of Infographics Design, Hussein Mohammad Al-Omari Feb 2026

The Role Of Motion Graphics In Enhancing The Effectiveness Of Infographics Design, Hussein Mohammad Al-Omari

Middle East Journal of Communication Studies

An infographic's primary objective is to satisfy the demands and expectations of its audience by presenting information in a logical and intelligible way. Recent developments in graphic design techniques have made several intricate techniques approachable by artists and designers, elevating the design process to a sophisticated profession that transcends media boundaries. Static infographics and animated infographics feature the same material; however, animated infographics have the benefit of displaying information via continuous motion and animated sequences rather than in static components or separate stages, and that’s because of the special features of animation, which attract a wider audience. They are also …


Selenium-Thioredoxin Axis Contributes To Ferroptosis Resistance In Pancreatic Cancer Cells, Arslan Amer, Micah Olamide Idowu, Aqsa Ahsan, Alyssa A. Abbas, Tahiyat Alothaim, Xiaohu Tang Feb 2026

Selenium-Thioredoxin Axis Contributes To Ferroptosis Resistance In Pancreatic Cancer Cells, Arslan Amer, Micah Olamide Idowu, Aqsa Ahsan, Alyssa A. Abbas, Tahiyat Alothaim, Xiaohu Tang

Michigan Tech Publications

Pancreatic ductal adenocarcinoma (PDAC) shows substantial heterogeneity in cysteine dependence and ferroptosis sensitivity. We identify two PDAC subtypes distinguished by EMT status: mesenchymal-like cells are highly cysteine-dependent and rapidly undergo ferroptosis upon cystine deprivation or system xc− inhibition, whereas epithelial-type cells are ferroptosis-resistant. Selenium supplementation protects cells from erastin-induced ferroptosis, and this protection persists even when intracellular glutathione (GSH) is depleted, supporting an additional GPX4-independent protective mechanism. Sepp1 knockdown does not alter sensitivity, indicating that selenium’s protective effect is independent of Sepp1. Instead, epithelial-type cells rely on both cytosolic and mitochondrial thioredoxin reductases (TrxR1 and TrxR2) to maintain ferroptosis …


Influence Of Aging And Exercise On Immune Blood Cells And Muscle Strength In Female Rats, Advait V. Dadi Jr, Dillon Harris, Quinten Pigg, Daniela Sayuri Inoue, Mariana Janini Gomes Feb 2026

Influence Of Aging And Exercise On Immune Blood Cells And Muscle Strength In Female Rats, Advait V. Dadi Jr, Dillon Harris, Quinten Pigg, Daniela Sayuri Inoue, Mariana Janini Gomes

International Journal of Exercise Science: Conference Proceedings

Aging is associated with alterations in immune cell profiles and declines in skeletal muscle function, which together contribute to increased vulnerability to disease and functional impairment. While aerobic exercise is known to improve muscle function and immune health, the effects of initiating exercise later in life, particularly in females, remain poorly understood. PURPOSE: This study examined the effects of aging and late-life aerobic training on blood cell counts and forelimb grip strength in female rats. METHODS: 20 female Fisher 344 rats were assigned into three experimental groups: Young (Y, 3 months (y, n = 6), Old (O, 21 …


Effects Of Nicotine Containing Juul E-Cigarette Vapor On Treadmill-Trained Rats’ Aerobic Fitness, Nicole C. Metzger, Raghav D. Sharma Feb 2026

Effects Of Nicotine Containing Juul E-Cigarette Vapor On Treadmill-Trained Rats’ Aerobic Fitness, Nicole C. Metzger, Raghav D. Sharma

International Journal of Exercise Science: Conference Proceedings

Electronic cigarettes (e-cigarettes) are often used as an alternative to traditional smoking, but their effects on physical fitness, especially during exercise, are not fully understood. PURPOSE: This study aimed to determine whether repeated exposure to nicotine-containing JUUL vapor affects aerobic exercise training and performance in male Long Evans rats. METHODS: Adult male Long Evans rats (n=12) underwent an 8-week progressive treadmill training program. After 4-weeks of treadmill training (pre-exposure), the rats were divided into two groups: one exposed to JUUL vapor for 10 minutes daily (5 days/week) and a control group exposed only to air. All rats completed running …


Late Life Aerobic Exercise Mitigates Age-Related Declines In Physical Function In Male And Female Rats, Dillon R. Harris, Quinten W. Pigg, Daniela S. Inoue, Andreea Trache, Mariana Janini Gomes Feb 2026

Late Life Aerobic Exercise Mitigates Age-Related Declines In Physical Function In Male And Female Rats, Dillon R. Harris, Quinten W. Pigg, Daniela S. Inoue, Andreea Trache, Mariana Janini Gomes

International Journal of Exercise Science: Conference Proceedings

While lifelong aerobic exercise (AE) is touted to counteract various age-related health detriments, the efficacy of AE initiated late in life remains unknown. PURPOSE: To investigate whether late life AE can reverse age-related physical and muscle decline in rats. METHODS: 52 male (M; n=22) and female (F; n=24) Fischer 344 rats (3- and 21-months) were randomly assigned in sedentary (SED) or exercise (EX) groups, composing 4 experimental groups per sex: Young SED (n=11; 6M, 5F) Young EX (n=12; 6M, 6F), Old SED (n=12; 5M, 7F) and Old EX (n=12; 6M, 6F). Prior to and after training, all animals underwent a …


Lasting Effects Of Doxorubicin On Skeletal Muscle Function During Recovery In Rats, Riya Meka, Quinten W. Pigg, Dillon R. Harris, Daniela Inoue Yoshimura, Mariana Janini Gomes Feb 2026

Lasting Effects Of Doxorubicin On Skeletal Muscle Function During Recovery In Rats, Riya Meka, Quinten W. Pigg, Dillon R. Harris, Daniela Inoue Yoshimura, Mariana Janini Gomes

International Journal of Exercise Science: Conference Proceedings

Doxorubicin (DOX) is a chemotherapy agent widely used to treat many types of cancer; however, DOX use is limited due to its adverse effects. Skeletal muscle wasting and weakness are among the significant adverse effects that can decrease quality of life in cancer patients. DOX’s lasting and late effects on skeletal muscle, after the cessation of treatment, have yet to be elucidated. PURPOSE: This study aims to investigate the effects of DOX on skeletal muscle function in rats following a 6-week recovery period after DOX treatment. METHODS: 21 male Wistar rats (10 weeks old) were assigned into two …


Reliability, Variability And Reproducibility Of Non-Invasive Blood Pressure Measurements In Rats, Paulo Engelke, Milena Samora Feb 2026

Reliability, Variability And Reproducibility Of Non-Invasive Blood Pressure Measurements In Rats, Paulo Engelke, Milena Samora

International Journal of Exercise Science: Conference Proceedings

Accurate blood pressure measurement is essential for advancing research in cardiovascular and exercise physiology. The most commonly used indirect method to measure blood pressure in animals is the tail-cuff system. In addition to requiring less expensive equipment and offering a non-invasive alternative to surgical blood pressure measurements, this technique allows for repeated assessments in conscious animals during both short- and long-term studies. Despite prior validation against the gold-standard methods (i.e., radiotelemetry and arterial catheterization), the reliability, variability and reproducibility of this technique have not been fully established. PURPOSE: The aim of the study was to evaluate the intra- and …


What Are Active People Made Of? Identifying Key Biological Correlates Of Physical Activity In Nationally Representative Databases, Isaac R. Ramos, Pratik Patil, Ayland C. Letsinger Feb 2026

What Are Active People Made Of? Identifying Key Biological Correlates Of Physical Activity In Nationally Representative Databases, Isaac R. Ramos, Pratik Patil, Ayland C. Letsinger

International Journal of Exercise Science: Conference Proceedings

Despite widespread awareness of the health benefits of physical activity, more than three-quarters of U.S. adults fail to meet national physical activity guidelines. Biological correlates may contribute to persistent differences in physical activity engagement beyond sociodemographic factors. PURPOSE: To identify biological correlates of physical activity levels in nationally representative U.S. adults. METHODS: Data were collected from the National Health and Nutrition Examination Survey (NHANES) 2021-2023 cycle. Physical activity was assessed using the Global Physical Activity Questionnaire and was expressed as minutes per week of leisure time moderate to vigorous physical activity (MVPA), with vigorous activity weighted by a …