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Articles 9031 - 9060 of 14542
Full-Text Articles in Entire DC Network
Comparative Analysis Of Gmm, Knn, And Vibe Background Subtraction Algorithms Applied In Dynamic Background Scenes Of Video Surveillance System, Maryam Yasir, Yossra Ali
Comparative Analysis Of Gmm, Knn, And Vibe Background Subtraction Algorithms Applied In Dynamic Background Scenes Of Video Surveillance System, Maryam Yasir, Yossra Ali
Engineering and Technology Journal
Background subtraction is the most prominent technique applied in the domain of detecting moving objects. However, there is a wide range of different background subtraction models. Choosing the best model that addresses a number of challenges is still a vital research area.Therefore, in this article we present a comparative analysis of three promising algorithms used in this domain, GMM, KNN and ViBe. CDnet 2014 is the benchmark dataset used in this analysis with several quantitative evaluation metrics like precession, recall, f-measures, false positive rate, false negative rate and PWC. In addition, qualitative evaluations are illustrated in snapshots to depict the …
A Comparative Study Of Perturb And Observe (P&O) And Incremental Conductance (Inc) Pv Mppt Techniques At Different Radiation And Temperature Conditions, Marwan Ahmad, Ali Numan, Dhari Mahmood
A Comparative Study Of Perturb And Observe (P&O) And Incremental Conductance (Inc) Pv Mppt Techniques At Different Radiation And Temperature Conditions, Marwan Ahmad, Ali Numan, Dhari Mahmood
Engineering and Technology Journal
The biggest challenge in the solar system is to extract the maximum output powerfrom photovoltaic (PV) panels under different solar radiation and temperatureconditions. This paper presents a comparative study between perturb and observe(P & O) and incremental conduction (INC) algorithms. These are the most popularalgorithms for tracking solar PV panels and extracting the maximum power point(MPP) under different climate conditions. The studied PV system and the MPPTtechniques have been investigated by simulation using MATLAB/Simulink. Thesimulation includes a boost converter, which increases the PV panel voltage bycontrolling the duty cycle. The obtained results show that the P & O performanceclose to …
Design Of A Sliding Mode Controller For A Prosthetic Human Hand’S Finger, Hussein Majeed, Saleem Kadhim, Alaa Jaber
Design Of A Sliding Mode Controller For A Prosthetic Human Hand’S Finger, Hussein Majeed, Saleem Kadhim, Alaa Jaber
Engineering and Technology Journal
In this research paper, the modeling and control of a tendon-driven, instead of joint motors, the prosthetic finger that mimics the actual human index finger were deliberated. Firstly, the dynamic model of the prosthetic finger is developed based on a 3-degree of freedom (DOF) articulated robot structure and utilizing the Lagrange equation. Then, the classical sliding mode control (CSMC) strategy was implemented to control the finger motion. To overcome the cons of CSMC, such as the chattering problem, an adaptive sliding mode controller (ASMC) was developed. MATLAB Simuphalange was used to perform the simulation after the necessary equations were derived. …
Design And Implementation Of Remote Real-Time Monitor System For Prosthetic Limbs, Hussein Mansoure, Hadeel Abdullah
Design And Implementation Of Remote Real-Time Monitor System For Prosthetic Limbs, Hussein Mansoure, Hadeel Abdullah
Engineering and Technology Journal
Persons with Lower-limb amputations experience movement restrictions resulting in worsening their life quality. Wearable sensors are often utilized to evaluate spatial and temporal qualities and kinetic parameters that provide the mechanism to create interactive monitoring of the amputee prosthesis system. Gait events and detection of the gait phase of amputee movement are essential to control the prosthetic devices of lower limbs. This paper presents real-time monitoring to individuals with lower limb amputation by using a medical wireless sensor. However, the proposed system used four medical sensor nodes (such as gait, temperature, the pressure of blood, blood oxygenation (SpO2) )for transmitted …
Optimization Process For Biodiesel Production From Waste Cooking Of Vegetable Oil By Microwave Irradiation, Raheek Ibrahim, Ahmed Reja, Abeer Kadhim
Optimization Process For Biodiesel Production From Waste Cooking Of Vegetable Oil By Microwave Irradiation, Raheek Ibrahim, Ahmed Reja, Abeer Kadhim
Engineering and Technology Journal
Biodiesel is the main alternative to diesel fuel today. The waste cooking vegetable oil can be used as a basic material in its preparation. Microwave irradiation is used in its production and it is considered one of the effective methods that do not consume much power. In this study, biodiesel is produce and determine the factors affecting the quality and quantity of production also investigated using experimental design technique. The effecting of operating variables power, time, and oil-to-ethanol molar ratio were studied, as well as the effect of interaction between operating variables on the quality of production. The optimum conditions …
The Wildlife Intelligence For Aviation Safety (Wild-Ai), Bao Khoa Tran
The Wildlife Intelligence For Aviation Safety (Wild-Ai), Bao Khoa Tran
Student Research Symposium (SRS)
Wildlife strikes pose a significant safety risk and economic burden to the aviation industry. Over 291,000 strikes have been reported in the U.S. since 1990, causing an estimated $248 million in annual losses. The Wild-AI (Wildlife Intelligence for Aviation Safety) project leverages cutting-edge technologies, including large language models (LLMs), machine learning (ML), explainable AI (XAI), and Unmanned Air Vehicles (UAV) imagery, to enhance wildlife hazard management at airports. Wild-AI transforms traditional Wildlife Hazard Assessments (WHAs) by integrating advanced data analytics and UAV monitoring. By utilizing historical wildlife-strike data and ML algorithms, we will identify key predictors of damaging strikes, such …
Building Competence And Confidence Through Experiential Learning: A Case Study Of The Bengal Triathlon, Caroline E. Faure Edd; Atc
Building Competence And Confidence Through Experiential Learning: A Case Study Of The Bengal Triathlon, Caroline E. Faure Edd; Atc
The COSMA Journal
This descriptive case study examines the perceived effectiveness of the Bengal Triathlon, an experiential learning (EL) activity integrated into a sport management course at Idaho State University. Drawing on student reflections over three years, the study highlights how this experience enhanced students’ confidence and skills in planning and managing sport events, particularly in high-pressure areas such as risk management, event logistics, and customer service. Despite participation being a course requirement, a noticeable shift in student attitudes was observed. Students moved from seeing the event as a mandatory task to taking full ownership, driven by increased motivation and enjoyment. This case …
Rupturing The Sport Management Classroom: Zine-Making For World-Making, Roc Rochon, Chen Chen
Rupturing The Sport Management Classroom: Zine-Making For World-Making, Roc Rochon, Chen Chen
Sport Management Collection
The on-going COVID-19 pandemic (and the pandemic of capitalism, white supremacy, imperialism, and colonialism, etc.) calls for imaginative, relevant, and critical approaches in sport management education to address diverse, socially, and culturally dynamic students. Yet the bulk of existing educational resources remain rooted in reinforcing systems of domination and the structure of on-going settler colonialism (Chen & Mason, 2019; hooks, 1994). A major challenge in traditional approaches to “updating” the curriculum fall short in challenging the banking mode of education (Freire, 1970). Following Amis and Silk’s (2005) call for a “rupture” of the reproduction of the status quo within sport …
I Am A Treaty Partner, Kyrie Fairbairn
Quantifying Location-Based Variability Of Regional Brain Metabolism Using Microsamples From Apoe Knock-In Mice, Jason G. Wells, Esteban G. Colman, John C. Price
Quantifying Location-Based Variability Of Regional Brain Metabolism Using Microsamples From Apoe Knock-In Mice, Jason G. Wells, Esteban G. Colman, John C. Price
Undergraduate Honors Theses
Apolipoprotein E (ApoE) is an important lipid transporter in the brain. There are three different ApoE variants: ApoE2, ApoE3, and ApoE4. Each of these variants either contribute to or protect against Alzheimer’s disease (AD). The Hippocampus (HC) and the Entorhinal Region (ER) of the brain consistently develop AD pathology first. We hypothesize that ApoE variants affect lipid and protein metabolism in these regions more strongly than in others. Differences in the regional regulation and the ApoE-isoform impacts of these metabolic pathways remain unknown.
We measured brain protein turnover rates in ApoE knock-in mice labeled with deuterated water. Using a laser …
Horizontal Gene Transfer In Neisseria, Wen Ting Dong
Horizontal Gene Transfer In Neisseria, Wen Ting Dong
Theses
Antibiotics are a special category of drugs that help treat bacterial infections by killing bacteria or hindering their growth and replication. Antibiotics are greatly significant in modern medical practices, providing an effective treatment for bacterial infections as well as enabling organ transplants, open surgeries, and chemotherapy to be possible. Unfortunately, cases of antibiotic resistance were observed shortly after the introduction of antibiotics. The appearance and spread of these resistant strains poses a significant threat to public health safety. The Centers for Disease Control (CDC) estimates there are 2,868,700 antibiotic-resistant bacterial and fungal infection cases per year in the United States, …
Dual Phagocytosis-Checkpoint Blockade Revitalizes Immune Surveillance In Mouse Models Of Glioblastoma, Jonghoon Ha, Yifan Wang, Yifan Ma, Annette Wu, Shiyan Dong, Seong Dong Jeong, Jared L Edwards, Mengyu Chang, Yen-Tzu Chang, Xiaotian Wang, Maurice Dufilho, Michelle Najarro Torres, Shannon Mccabe, Weiye Deng, Adam J Grippin, Jeffrey S Weinberg, Shaan M Raza, Franco Demonte, Ian E Mccutcheon, Sujit Prabhu, Sherise D Ferguson, Chibawanye I Ene, Kadir Akdemir, Sreyashi Basu, Sonali Jindal, Benjamin R Schrank, Jian Hu, Sangeeta Goswami, Vinay K Puduvalli, Frederick F Lang, Kristin Huntoon, Padmanee Sharma, Betty Y S Kim, Wen Jiang
Dual Phagocytosis-Checkpoint Blockade Revitalizes Immune Surveillance In Mouse Models Of Glioblastoma, Jonghoon Ha, Yifan Wang, Yifan Ma, Annette Wu, Shiyan Dong, Seong Dong Jeong, Jared L Edwards, Mengyu Chang, Yen-Tzu Chang, Xiaotian Wang, Maurice Dufilho, Michelle Najarro Torres, Shannon Mccabe, Weiye Deng, Adam J Grippin, Jeffrey S Weinberg, Shaan M Raza, Franco Demonte, Ian E Mccutcheon, Sujit Prabhu, Sherise D Ferguson, Chibawanye I Ene, Kadir Akdemir, Sreyashi Basu, Sonali Jindal, Benjamin R Schrank, Jian Hu, Sangeeta Goswami, Vinay K Puduvalli, Frederick F Lang, Kristin Huntoon, Padmanee Sharma, Betty Y S Kim, Wen Jiang
Faculty, Staff and Student Publications
Macrophage-mediated phagocytosis of tumor cells elicits potent antitumor immunity. Nonetheless, sole-blockade of the anti-phagocytosis molecule CD47 has yielded insufficient therapeutic outcomes. Here, we report that glioblastoma (GBM) cells expressed abundant levels of phagocytosis checkpoint CD24. We further show that dual blockade of CD24 and CD47 synergistically enhances the pro-phagocytic activity of macrophages, thereby improving tumor antigen cross-presentation and activating the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway. This innate immune activation facilitates T cell infiltration into tumors and sensitizes tumors to anti-PD1 therapy, improving survival outcomes in murine GBM models, including immunosuppressive tumors reflecting human GBM-like features. Thus, our …
Perspectives On Food Sovereignty In Chicago, Camden Bruce Blowers
Perspectives On Food Sovereignty In Chicago, Camden Bruce Blowers
Capstone Projects – Politics and Government
The research question for this project focuses on food sovereignty. “How do individuals working with food in Chicago identify their role in promoting food sovereignty?” is a research question that expands with some nuance into the question of “who” individuals are in terms of political orientation. When asked to identify political ideology and economic ideology, the values can be greater quantified. Using mixed-methods, this paper critically assesses perspectives of individuals working with food in Chicago. The online survey enumerates the individual perspectives, food culture, and sociopolitical interactions of food sellers, producers, and advocates. Ten interviews further establish 1) the sociopolitical …
The George-Anne Daily, Georgia Southern University
The George-Anne Daily, Georgia Southern University
George-Anne Media Group: Newsletters & Magazines
No abstract provided.
Patient And Healthcare Professionals' Perceptions Of Educational Tools To Reduce Urine Culture Contamination In Outpatient Clinics: A Qualitative Study., Ashley Collazo, Trenton M Haltom, Johanan Luna Rodriguez, Kiara Olmeda, Azalia Mancera, Fabrizia Faustinella, Michael K Paasche-Orlow, Zach Landis-Lewis, Roger Zoorob, Barbara W Trautner, Larissa Grigoryan
Patient And Healthcare Professionals' Perceptions Of Educational Tools To Reduce Urine Culture Contamination In Outpatient Clinics: A Qualitative Study., Ashley Collazo, Trenton M Haltom, Johanan Luna Rodriguez, Kiara Olmeda, Azalia Mancera, Fabrizia Faustinella, Michael K Paasche-Orlow, Zach Landis-Lewis, Roger Zoorob, Barbara W Trautner, Larissa Grigoryan
2020-Current year OA Pubs
OBJECTIVE: Iteratively develop educational tools (instructional video and flyer) to improve midstream clean catch (MSCC) urine sample collection using patient and healthcare professionals' input.
DESIGN: Multi-method qualitative study.
SETTING: Outpatient clinics in Houston, Texas, United States.
PARTICIPANTS: Adult patients recruited from public and private clinics (
METHODS: Twelve patient interviews and three focus groups with HCPs (May 2024-November 2024). Interviews discussed patient experiences using the educational tools to guide urine specimen collection. Focus groups elicited HCPs' perspectives on the comprehensibility and utility of the tools in their respective clinics. We identified themes using directed content analysis.
RESULTS: We garnered insight …
Productive Systems And The Problems Of Agricultural Development, R. Badouin
Productive Systems And The Problems Of Agricultural Development, R. Badouin
Revue Marocaine de Droit, d'Economie et de Gestion (Moroccan Journal of Law, Economics and Management)
This article discusses how agricultural development requires changes in productive systems under conditions of population growth, rising incomes, and urbanization. It distinguishes between cropping systems, production systems, and farm management systems, and examines how each should evolve in response to food demand. The author analyzes the balance between food crops and export crops, as well as between plant and animal production, emphasizing food security, resource efficiency, and the risks of dependence on external markets or animal-based consumption patterns. The article frames agricultural strategy as a structural response to development pressures rather than a purely technical adjustment.
Concealed Feudal Privilege: The Past And The Future In The Making Of Property Law, Ugo Mattei
Concealed Feudal Privilege: The Past And The Future In The Making Of Property Law, Ugo Mattei
Texas A&M Journal of Property Law
This article critically examines the evolution of private property law from its origins in European and American legal traditions to its current entanglement with global capitalism and digital technology. Drawing on historical analysis and recent scholarship, the author argues that modern private property, far from realizing the promise of emancipation from feudal privilege, has served to cloak new forms of class domination. Through narratives crafted by jurists, property law has continually mediated the interests of the powerful and marginalized popular masses, substituting class-based privilege for blood privilege. The article explores how legal concepts—such as privacy and the social function of …
Property In The Short Twentieth Century, Fernando Atria
Property In The Short Twentieth Century, Fernando Atria
Texas A&M Journal of Property Law
This article examines the evolution of property law in the "short twentieth century," focusing on the shift from a classical, unified, and individualistic concept of property toward one defined by its "social function." Drawing on Anna di Robilant's historical analysis and legal developments in Chile, the article discusses three interrelated strands of the social critique of property: the doctrine of abuse of right, the concept of the social function of property, and the pluralist ("tree-like") model of property regimes. It contrasts the Will Theory and Interest Theory of rights to clarify the nature of "fractured rights," where legal powers may …
From Farm To Fork, And Beyond: The International Politics Of Food Standards, Julia E. Srnec
From Farm To Fork, And Beyond: The International Politics Of Food Standards, Julia E. Srnec
The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University
Food safety standards are incredibly politically charged due to how much they can differ between countries and how implementing new standards in a country can impact the economy of those depending on the exports of food products. The political division regarding food safety standards can begin to be understood once the impacts on national and international economics, as well as the consequences of regulations beyond the economy, are considered. Nongovernmental organizations such as the World Health Organization help to mitigate conflict over trade policy disagreements, however some divisions persist.The use of non-tariff barriers on the imports of food-related goods can …
Microrna-625-3p Increases Chemosensitivity In Ovarian Cancer Cells Through Decreasing Ssx2ip-Mediated Cisplatin Export In Extracellular Vesicles, Chi-Lam Au-Yeung, Tetsushi Tsuruga, Marina A Talor, Yadira J Pacheco, Guangan He, Zahid H Siddik, Byeong J Cha, Suet-Ying Kwan, Kwong-Kwok Wong, Kay-Pong Yip, Samuel C Mok
Microrna-625-3p Increases Chemosensitivity In Ovarian Cancer Cells Through Decreasing Ssx2ip-Mediated Cisplatin Export In Extracellular Vesicles, Chi-Lam Au-Yeung, Tetsushi Tsuruga, Marina A Talor, Yadira J Pacheco, Guangan He, Zahid H Siddik, Byeong J Cha, Suet-Ying Kwan, Kwong-Kwok Wong, Kay-Pong Yip, Samuel C Mok
Faculty, Staff and Student Publications
Introduction: Advanced-stage high-grade serous ovarian cancer (HGSC) is a disease that is difficult to manage due to its heterogeneous clinical behavior. No reliable prediction of response to chemotherapy is currently available and the overall survival rate remains poor. Herein, we sought to determine the molecular mechanisms by which microRNAs (miRNAs) confer chemoresistance in ovarian cancer and demonstrate the efficacy of targeting miRNAs to sensitize HGSC to cisplatin treatment.
Methods: Next-generation miRNA sequencing was performed using microdissected HGSC specimens to identify an miRNA signature for intrinsic chemoresistance, and miR-625-3p was selected for further study. The effects of miR-625-3p on cisplatin sensitivity …
Khirbat Shumeila: Buildings From The Persian And Hellenistic Periods And Installations In Their Surroundings / ח'ירבת שומילה: מבנים מהתקופות הפרסית וההלניסטית ומתקנים בסביבתם, Elena Kogan-Zehavi
Khirbat Shumeila: Buildings From The Persian And Hellenistic Periods And Installations In Their Surroundings / ח'ירבת שומילה: מבנים מהתקופות הפרסית וההלניסטית ומתקנים בסביבתם, Elena Kogan-Zehavi
Qadum: Journal of Excavation Reports from Israel
Salvage excavations at Khirbat Shumeila identified four strata spanning the late Persian, early Hellenistic, Roman and Byzantine periods. The primary remains comprise two structures: Building 25, which features two distinct construction phases dating to the late Persian and early Hellenistic periods, and Building 6, dating to the Hellenistic period. These buildings, along with the installations uncovered within and around them, indicate intensive agricultural activity, suggesting their function as farmsteads. Their proximity to additional adjacent farmsteads implies their integration into a regional agricultural network established during the fourth-century BCE Persian administrative reorganization—a configuration that continued uninterrupted into the early Hellenistic period. …
Waste-To-Energy Innovations And Advances In Hydrothermal Carbonization, Microwave, And Pyrolysis Processes: A Review, Ali Mohammed Saleh, Noah Mohammed Saleh, Mahmod A. Abdulqader, Hadi Hamdi Mahdi, Jafar Keighobadi, Omar K. Ahmed, Khalil Farhan Yassin, Azil Bahari Bin Alias, Omar Abed Habeeb, Ibrahim Awad Mohammed
Waste-To-Energy Innovations And Advances In Hydrothermal Carbonization, Microwave, And Pyrolysis Processes: A Review, Ali Mohammed Saleh, Noah Mohammed Saleh, Mahmod A. Abdulqader, Hadi Hamdi Mahdi, Jafar Keighobadi, Omar K. Ahmed, Khalil Farhan Yassin, Azil Bahari Bin Alias, Omar Abed Habeeb, Ibrahim Awad Mohammed
AUIQ Complementary Biological System
The accelerating global generation of municipal solid waste, coupled with escalating energy demands, presents one of the most pressing sustainability challenges of the 21st century. Conventional waste disposal pathways, such as landfilling and incineration, exacerbate environmental degradation and resource loss. In response, thermochemical technologies—specifically hydrothermal carbonization (HTC), microwave-assisted processing, and pyrolysis—have emerged as promising strategies for waste valorization and renewable energy recovery. This review critically examines recent advancements in these technologies, emphasizing their roles in converting diverse waste streams into high-value energy carriers and carbon-rich materials. Comparative analysis reveals that HTC operates efficiently under subcritical water conditions, producing hydrochar with …
The Sentience Of The Horse And The Philosophy Of Natural Horsemanship: Implications For Hrd Leadership, Rob E. Carpenter
The Sentience Of The Horse And The Philosophy Of Natural Horsemanship: Implications For Hrd Leadership, Rob E. Carpenter
Human Resource Development Faculty Publications and Presentations
This paper advances a biologically grounded philosophy of leadership through the lens of Natural Horsemanship. It reframes leadership as an embodied, sentient process rather than a purely cognitive or behavioral construct. Drawing from neuroscience, affective biology, sociology, and human resource development (HRD), it proposes that the horse–human relationship provides a living model for relational intelligence. The horse’s exquisite attunement to human emotion—mediated through limbic regulation and bio-behavioral synchrony—reveals that influence arises not from authority but from coherence. Leadership, like horsemanship, is a reciprocal act of co-regulation in which trust, safety, and communication are revealed through physiology before language. By examining …
The Role Of Pet-Parenting Attitudes In Shaping Consumer Behavior Toward Preventive And Wellness-Oriented Pet Care, Jin Hua Jian, Chee Vui Wong, Jiangwei Yang
The Role Of Pet-Parenting Attitudes In Shaping Consumer Behavior Toward Preventive And Wellness-Oriented Pet Care, Jin Hua Jian, Chee Vui Wong, Jiangwei Yang
Jesselton Journal of Educators and Scholars
The increasing tendency to view pets as family members has transformed consumer behaviour in contemporary pet care markets, particularly in relation to preventive and wellness-oriented consumption. This study examines how pet-parenting attitudes shape consumer decision-making and expenditure on preventive pet care in an emerging urban context. Grounded primarily in Consumer Culture Theory, with the Theory of Planned Behavior as a supporting lens, the study adopts a quantitative approach using survey data collected from 400 urban pet-owning households. The findings indicate that pet-parenting attitudes exert a significant positive influence on preventive and wellness-oriented pet care expenditure. This influence operates both directly …
Movement As Worship: Deepening Religious Practices Through Bodily Awareness And Expression, Jordan M. Halterman
Movement As Worship: Deepening Religious Practices Through Bodily Awareness And Expression, Jordan M. Halterman
Undergraduate Honors Theses
This creative project explores how bodily awareness and expression deepen personal religious practice, with particular attention to the theology from the Church of Jesus Christ of Latter-day Saints and embodied dance experience. Drawing from theological scholarship (Aquino and Gavrilyuk 2022, Brown 2014, Jordan 2016, Summers 2014, Taylor 2023, Zaluchu 2021), dance and liturgical studies (Debenham and Debenham 2008, Hackney 2020, Kent and Tucker 1996, Kline-Chesson 1989, Roseman 2015), and teachings from the Church of Jesus Christ of Latter-day Saints (Bednar 2001, Lloyd 1998, Nelson 2008, Tanner 2005, Wisco and Seferovich 2014), this study reveals that the body is not peripheral …
Flisser, Miriam, Philip Chan
Flisser, Miriam, Philip Chan
Bronx Jewish History Project
Miriam Flisser was born in Europe right after World War II to Jewish partisan parents. They fled danger and arrived in New York as refugees, settling in the Bronx. She grew up in safe, lively neighborhoods like Mott Haven and Pelham Parkway, speaking Yiddish at home until she learned English from kids on the street. Her dad was a skilled kosher butcher who later bought apartment buildings; the family kept a warm, traditional Jewish home.
Miriam excelled in Bronx schools, went to Bronx Science, then NYU’s Bronx campus and Albert Einstein Medical School (graduating a year early). She became a …
Crossing The Finish Line Towards A Disease-Modifying Treatment For Angelman Syndrome, Matthew C Judson, Jason J Yi, Et Al.
Crossing The Finish Line Towards A Disease-Modifying Treatment For Angelman Syndrome, Matthew C Judson, Jason J Yi, Et Al.
2020-Current year OA Pubs
Recent progress in the development of genetic therapies promises that impactful treatments for single-gene neurodevelopmental disorders are imminent. But can derailed neurodevelopmental processes be mended after broken genes are replaced or otherwise restored? The results of ongoing clinical trials for Angelman syndrome will soon yield answers to this pressing question, yet the trials face significant obstacles. Here we identify insights needed to aid the quest for a disease-modifying Angelman syndrome therapy, which could serve as a roadmap for the expeditious development of genetic therapies for other single-gene neurodevelopmental disorders.
Three-Dimensional Printing Of The Epineurium For Peripheral Nerve Repair: A Comprehensive Review Of Novel Scaffolds For Nerve Conduits, Alynah J. Adams, Iulianna C. Taritsa, Kaavian Shariati, Aaron Dadzie, Jose A. Foppiani, Maria Jose Escobar-Domingo, Daniela Lee, Angelica Hernandez-Alvarez, Kirsten Schuster, Helen Xun
Three-Dimensional Printing Of The Epineurium For Peripheral Nerve Repair: A Comprehensive Review Of Novel Scaffolds For Nerve Conduits, Alynah J. Adams, Iulianna C. Taritsa, Kaavian Shariati, Aaron Dadzie, Jose A. Foppiani, Maria Jose Escobar-Domingo, Daniela Lee, Angelica Hernandez-Alvarez, Kirsten Schuster, Helen Xun
School of Medicine Publications
Background: Nerve conduits are used to bridge peripheral nerve defects caused by trauma, iatrogenic injury, or oncologic disruption. Three-dimensional (3D) biomimetic scaffolds for peripheral nerve regeneration have advanced significantly in recent years, driven by improvements in printing technology and neuronal seeding techniques. We report on published designer conduits that can recreate the epineurium, a critical yet challenging-to-manufacture feature of nerve tissue.
Methods: A medical librarian conducted a literature search for our systematic review on EMBASE, Web of Science, and PUBMED, following PRISMA guidelines, for articles from January 2010 to January 2026 for the systematic review. Descriptive statistical analysis was performed …
A Novel Laparoscopic Renal Denervation System In A Preclinical Swine Model, Linwei Zhao, Wei Yang, Binbin Zhu, Yahui Liu, Peng Tian, Xinyu Guo, Yang Dong, Zhiqiang Fan, Huiping Li, Yu Feng, Lijie Zhu, Minfu Bai, Qiuping Zhao, Xingkun Zhang, Chenchen Si, Qianqian Cheng, Gan-Xin Yan, Chuanyu Gao
A Novel Laparoscopic Renal Denervation System In A Preclinical Swine Model, Linwei Zhao, Wei Yang, Binbin Zhu, Yahui Liu, Peng Tian, Xinyu Guo, Yang Dong, Zhiqiang Fan, Huiping Li, Yu Feng, Lijie Zhu, Minfu Bai, Qiuping Zhao, Xingkun Zhang, Chenchen Si, Qianqian Cheng, Gan-Xin Yan, Chuanyu Gao
Department of Medicine Faculty Papers
Laparoscopic renal denervation (RDN) represents a specialized approach for hypertension, particularly when conventional methods face limitations. While catheter-based RDN has demonstrated significant efficacy in recent large-scale clinical trials and has been integrated into international guidelines, its effectiveness can be constrained by complex renal anatomy or incomplete ablation. We developed a novel laparoscopic RDN system, comprising an integrated radiofrequency (RF) clamp, RF generator, and cooling pump, to achieve more controlled adventitial ablation. This study aims to evaluate the safety, feasibility, and optimal parameters of this new system in a preclinical swine model. Sixteen pigs were divided into an immediate group ( …