Digital Commons Network^™

Assessing Decision Making Under Risk And Dynamic Task Environments In Humans, Dylan J. Cato

GS4 Student Scholars Symposium

This research evaluates the theoretical foundations of recent embodied and enacted decision- making models(Baker., et al  2022) , specifically investigating whether "urgency" serves as a domain-general mechanism for reward-rate maximization. Across three experiments using a reward-performance contingency, we compare traditional decision-making frameworks with urgency-based theories to determine how participants navigate task demands and whether optimality assumptions hold (Reynaud, et al 2020). A primary focus involves testing whether motor excitability increases directly with evidence, or if "higher-level" deliberation occurs in parallel with se Using the Generalized Drift-Diffusion Model (GDDM) framework via PyDDM  (Shinn, et al 2020), we will …

Assessment Of Airborne Cultural Fungi Indoors And Outdoors In A Rural Veterinary Clinic, Elena Ortez, Oluwatosin Jegede, Dorothy Seybold, Daeshjea Mcgee, Atin Adhikari, Ally Holmes

GS4 Student Scholars Symposium

Background and Objectives: Veterinary clinics can inadvertently release and propagate bacteria through several mechanisms, primarily due to contaminated surfaces, insufficient cleaning protocols, and, in some instances, direct transmission from infected animals or staff. Given that these clinics are high-traffic environments, they can serve as hotspots for clinic-acquired infections if rigorous hygiene practices are not upheld. This study evaluated airborne bacterial concentrations in different areas of a veterinary clinic compared to outdoor ambient air by calculating the indoor-to-outdoor ratios.

Methods: Airborne culturable bacterial samples were collected using a Biostage Impactor across eight internal zones including waiting areas, treatment rooms, and wards …

Let's Talk About Age, Baby!, Kathryn Ravasio, Hector Mendoza

Undergraduate Research and Engagement Symposium

The Longevity Gap refers to the intriguing difference in life expectancy between males and females. In C. elegans, XX chromosome animals live longer than those with XO chromosomes. This study examines if XOL-1, the protein that acts as the master regulator of sex determination, is involved in this difference in aging.

Morphological Identification Of Echinostomas Found Within Dabbler And Diving Ducks, Sammy Schneider, Emma Harms, Miana Risser, Madison Becker

Research & Creative Achievement Day

Most ducks can be separated into two categories, dabblers or divers, depending on their feeding guild. Dabbler ducks are surface feeders and consume vegetation while diver ducks feed below the surface and consume aquatic animals. The Echinostoma species present in ducks may vary depending on their feeding guild. Three species of ducks from various regions of Wisconsin were donated by hunters for examination of endoparasites, particularly those from the genus Echinostoma. The sites of collection included Trempealeau, Marionette, and Onalaska. One species of dabbler duck, Gadwall (Mareca strepera), and two species of diver ducks, Lesser Scaup (Aythya affinis) and Canvasback …

The Evolution Of Accounting: Historical Bookkeeping And Double Entry, Linda N. Moua

Research & Creative Achievement Day

In present-day accounting, technology  has transformed the efficiency and effectiveness of transaction recording.  Microsoft Excel has become a standard tool since its launch in the 1980s and has  quickly replaced handwritten work. This research aims to analyze the origins  of accounting, specifically in bookkeeping and double-entry, and how it has  proven to be the language of business from the beginning. This research will  initially look at stone tablets from the Mesopotamian Era and into the  development of double entry, with how its evolved origins are still similar  and different today. Other than the history of bookkeeping and double entry,  there …

Comparing Dissection Vs Literature Data Of Cestodes In Ducks, Sophia B. Cross

Research & Creative Achievement Day

Cestodes are a class of parasites that are often found in vertebrate animals, specifically ducks. Research conducted by Winona State University students showed that cestodes were the most prevalent type of parasites found within ducks. However, outside research provides controversy as to whether this is actually true. Ducks were dissected by Winona State students over the past seven years, and their internal organs were carefully inspected under a light microscope. Ducks were donated by hunters, mostly harvested along the Mississippi River, from Buffalo City, WI to Winona, MN. Parasites were obtained, stored, and labelled from each duck. A dichotomous key …

Reframing Alpha-Gal Syndrome As A One Health Oral Health Risk: A Theoretical Model For Dental Safety And Policy Reform, Oyebolu Aderinola Akinkugbe, Akuchinyere Titus-Okpanachi, Oluwatosin Marylyn Oduneye

Liberty University Research Week

No abstract provided.

Manual Tissue Slicer Designed For Ovarian Tissue Cryopreservation, Levon Shukrian, Caleb Anene, Daniel Archer, Derek Works, Jack Durham, Joby Anthony, Jumana Rizk, Maria Mendoza Lopez, Shanice Rerrie

Liberty University Research Week

Fertility preservation techniques such as ovarian tissue cryopreservation and autotransplantation provide important options for patients at risk of primary ovarian insufficiency due to medical treatments or disease. A critical step in this process is the preparation of uniform ovarian cortical slices (0.5–1.5 mm thick) that preserve follicular architecture prior to cryopreservation. However, the discontinuation of the Stadie-Riggs tissue slicer, previously used for fresh tissue slicing, has created a significant gap in both translational research and clinical practice. To address this need, a compact manual ovarian tissue slicer was designed and constructed using biocompatible 316L stainless steel and borosilicate glass. The …

Artificial Meaning?, Thomas R. Lee, Jesse Egbert

Florida Law Review

The textualist turn is increasingly an empirical one—an inquiry into ordinary meaning in the sense of what is commonly or typically ascribed to a given word or phrase. Such an inquiry is inherently empirical. And empirical questions call for replicable evidence produced by transparent methods—not bare human intuition or an arbitrary preference for one dictionary definition over another. Both scholars and judges have begun to make this turn. They have started to adopt the tools used in the field of corpus linguistics—a field that studies language usage by examining large databases (corpora) of naturally occurring language.

This turn is now …

Identification Of An Unknown Bacterial Species From A Sink Handle, Angelo Ricarte, Ahman Dye

Undergraduate Research and Engagement Symposium

This project aims to identify an unknown bacterial species isolated from a sink handle. Using a series of tests, the bacterium’s physical appearance, growth conditions, and metabolic characteristics will be examined. Its shape, colony appearance, and responses to different biochemical tests will help narrow down its identity. By comparing these results with the profiles of known bacteria, this project aims to determine which species is present and better understand the types of microbes commonly found on everyday objects.

Non-Alcoholic Fatty Liver Disease, Diet And Contributing Factors: A Narrative Literature Review, Rachel Joseph, Ashley Tharpe, Sherri Ann Walker

Wisdom & Compassion: The LUSON Journal

Objectives: The purpose of this narrative literature review is to explore the relationship between Non-alcoholic fatty liver disease (NAFLD) and dietary habits, and identify factors that contribute to the development, progression, and potential management of NAFLD.

Methods: Search terms such as non-alcoholic fatty liver disease (NAFLD), diet, and nutrition, including plant-based and vegetarian diets, were used to identify 45 peer-reviewed publications published within the last five years.

Results: Dietary factors, biological, environmental, obesity, mental health, and genetic factors can contribute to the development of NAFLD. This multisystem problem can have economic, social, and psychological consequences that affect a person’s quality …

Multi-Omics Systems-Guided Insights Of Withanolide And Other Bioactives Contributions To Anti-Stress And Endurance Outcomes In Withania Somnifera, Deepak Mundkinajeddu

Oxford ICSB

Conventional Ashwagandha standardization is largely focused on total withanolide quantification, without insights on the functional contribution of other phytochemical fractions. In this discovery-driven development program, orthogonal array–based model combined with predictive transcriptomics was used to delineate the relative biological roles of withanolide and other bioactive components within Withania somnifera extracts. Validated animal models showed that withanolide-enriched fractions significantly reduced serum cortisol (p< 0.05), while other bioactive-enriched fractions significantly increased run-time to exhaustion (p< 0.05), confirming anti-stress and endurance mechanisms. By linking the phytochemical profile with predicted biological pathway activity, the composition of the extract is rationally optimized for the development of a standardized extract (Ashwa.30), designed to deliver both anti-stress and endurance benefits at a dose of 30 mg. Clinical evaluation of the Ashwagandha extract demonstrated significant reductions in perceived stress scores and circulating cortisol levels, alongside measurable improvements in endurance parameters compared to placebo (p< 0.05), confirming translational alignment from preclinical discovery to human outcomes. Untargeted metabolomic profiling revealed enrichment of glycine and serine metabolism, methionine metabolism, phenylalanine and tyrosine metabolism, and homocysteine degradation pathways. These integrated metabolic changes worked together to improve energy production, support mitochondrial repair, maintain antioxidant balance, and help reset the body’s stress response system. This work presents a systems-biology–based approach to holistic Ashwagandha standardization, integrating withanolides and complementary bioactivities. It establishes a precision-driven framework for clinically validated adaptogenic efficacy.

Temporal Variation In Dna Methylation Over 115 Years Post Introduction Facilitate Success Of House Sparrows, M. Ellesse Lauer, J. Dylan Maddox, Kevin D. Kohl, Mark Ravinet, Lynn B. Martin, Aaron W. Schrey

GS4 Student Scholars Symposium

House sparrows (Passer domesticus) have colonized most continents within the last 200 years. As such, they represent a unique study system for understanding the role that epigenetic mechanisms play in an individual’s responses to rapid environmental changes. DNA methylation facilitates the introduction success of non-native sparrows by compensating for reduced genetic diversity and supporting changes to phenotypes. In non-native populations of house sparrows, more recently introduced populations have higher variance in DNA methylation and respond to simulated infections with a greater magnitude of change in DNA methylation. To determine how DNA methylation changes temporally across 115 years post …

Briefly Noted: Raven And Crow: The Mythology, Art And Science Of Our Favorite Black Birds By Ellen W. Williams By Ellen W. Williams, Janet Croft

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Review of Raven and Crow: The Mythology, Art and Science of Our Favorite Black Birds by Ellen W. Williams, McFarland, 2025.

Russell Hoban: Faithful To The Strange By Graeme Wend-Walker, Nicholas Birns

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This is a review of David Wend-Walker's critical book on the fiction of Russell Hoban.

From Viðkenning To Valarindi: The Enigma Of Goldberry And The River-Woman, Derek Simon

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

THIS IS A TWO-PART ARTICLE. IN ORDER TO READ OR DOWNLOAD THE OTHER PART, FOLLOW THE LINK AT THE END OF THIS ABSTRACT.

Building upon the previous examination of the eddic and skaldic contours of Goldberry’s River kenning names, this reading of Goldberry’s enigma focuses on the mythological referents of her kinship relations and their narrative consistency in the legendarium.  Tending to the intrinsic connection between “[t]he incarnate mind, the tongue, and the tale” (Tolkien, On Fairy Stories, 41), I contend that the poetics of kenning diction sustain if not demand a reading of the River-woman references mythologically through …

What Are C.S. Lewis's Eldila And Why Do They Matter?, Joseph Weigel

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This article explores the eldila from C.S. Lewis’s Ransom Trilogy. Many of the eldila in the trilogy are angelic beings. However, Lewis uses the nine orders of angels in the trilogy and different eldils correspond to different types of angels within the hierarchy. Additionally, eldila, on occasion, can refer to the entirety of the supernatural realm, including the mysterious longaevi. Through the trilogy, Lewis is portraying the rich supernatural worldview presented in the Scriptures that is so often ignored, even by Christians. For Lewis, angels, devils, and the whole realm of spirits, was a reality of the cosmos, …

Pier’S Barn And Aslan’S Stable: Satire And Sublimity In Langland’S Piers Plowman And Lewis’S The Last Battle, Tiffany E. Schubert

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

The stable in The Last Battle is rather mysterious. It seems a random bit of architecture plopped in Narnia, whose primary structures are cozy caves or castles by the sea. Of course, the stable is an important Christian symbol, the humble birthplace of Christ himself. Nevertheless, Lewis’s stable does not function in any straightforward way as the Narnian version of “Away in a Manger.” Rather, it is a place of deception and violence, housing the false Aslan and serving as the focal point of an apocalyptic battle that ends with the destruction of all Narnia. There is medieval precedent for …

Unmasking Ashwagandha Controversy: Safety, Toxicity, And Adulteration, Tahir Maqbool Mir

Oxford ICSB

Ashwagandha (Withania somnifera) is an adaptogenic shrub valued for its roots, which support systemic health. Increasing use has raised safety concerns about adulteration and hepatotoxicity. The roots of ashwagandha are primarily preferred for systemic health, while the leaves were traditionally reserved for topical applications to treat joint inflammation and promote wound healing.  Although generally considered safe, ashwagandha supplements have been linked to drug-induced liver injury, including cholestasis, jaundice, and pruritus. Reports from various organizations like LARB in the Netherlands indicate a rise in liver toxicity cases, possibly due to cytotoxic withafrin A and DNA-damaging withanone. A major concern is widespread …

Advancements In Botanical Toxicology, Characterization, And Regulatory Frameworks, Paula Brown

Oxford ICSB

No abstract provided.

Determinants Of Opioid-Relevant Exposure From 7-Hydroxymitragynine Products In The Evolving U.S. Marketplace, Igor Koturbash, Scott Alsbrook, George Pro

Oxford ICSB

Kratom’s U.S. market has rapidly evolved from largely botanical powders and capsules to products enriched in 7-hydroxymitragynine (7-OH), a potent mu-opioid receptor agonist that is typically present only at trace levels in leaf material. To quantify downstream behavioral health burden and contextualize it with real-world signals of product diffusion, we analyzed National Survey on Drug Use and Health (NSDUH) data (2021-2023) alongside public health alert trends and systematic online product surveillance. In NSDUH, 5.8% of adults met criteria for serious mental illness (SMI). SMI increased by 150% among adults with combined opioid use disorder (OUD) and kratom use between 2021 …

Naturally Derived Kratom Extracts: Toxicological Evaluation In Humans And Rodents, Sibyl Swift

Oxford ICSB

Peer-reviewed literature provides limited toxicological data on the consumption of naturally derived kratom extracts. Given the increasing use of kratom products, understanding their safety profile is critical for public health and regulatory decision-making. To address this gap, we conducted a rodent toxicology assessment and a controlled human clinical study. Human Clinical Study: Healthy male and female participants consumed specified kratom extracts daily for 14 consecutive days under controlled conditions. Clinical observations and biochemical markers were monitored throughout the study. Rodent Toxicology Study: Equivalent extract doses were administered to rodents for 90 days to evaluate subchronic exposure. Assessments included body weight, …

Epigenetic Variation Of American Alligators (Alligator Mississippiensis) In The Okefenokee Swamp, Mark Hoog, Kimberly M. Andrews, Aaron W. Schrey

GS4 Student Scholars Symposium

An animal's survival is heavily influenced by how well adapted it is to the environment in which it lives; however, phenotypes are only able to change so quickly. Epigenetics allows for greater phenotypic plasticity through molecular mechanisms without altering the DNA sequence. DNA methylation is the most widely studied epigenetic mechanism. It has shown the ability to alter gene expression and may even be able to compensate for a lack of genetic variation. Changes in DNA methylation are often caused by stressors that range from anthropogenic causes to natural occurrences. We sought to examine the effect of environmental factors on …

Characterization Of Bacteria In Cattle Specimens, Jacob D. Hanson, Josie M. Tieskoetter

Research & Creative Achievement Day

Cattle nasal cavities provide a favorable environment for microbial colonization and can habit a wide population of bacteria, including opportunistic and pathogenic species. The objective of this research was to isolate, characterize, and identify bacteria present is nasal swap specimen collected from multiple calves. Samples were cultured and analyzed using selective and differential media, Gram staining, spore staining, and a range of biochemical assays. Several bacterial species were identified including the genus Corynebacterium and Streptococcus while some isolates could not be identified using classical biochemical methods alone. These results demonstrate that calf nasal specimens commonly contain diverse bacterial populations, some …

A Metaphor Criticism On Disney-Pixar's Elemental, Erin O. Donovan

Research & Creative Achievement Day

Immigration is a contested topic, having a variety of opinions, both negative and positive throughout history. Films are important to study, as they can frame important topics, like immigration, and shape our understanding. Animated children's films have the ability to deliver messages and create meaning through a fun, innocent vehicle that disguises these messages. The use of metaphors in this case, are a delivery method of underlying messages, as metaphors can be strategically used to go unnoticed in a story. This study sets out to use metaphor criticism on the Disney-Pixar film, Elemental (2023), by Peter Sohn, to examine its …

Co2 Washout Performance Of Single-Prong And Dual-Prong High-Velocity Therapy, Robert Kacinski

Liberty University Research Week

Computational models were used to investigate the flow in the upper airway during high-velocity therapy delivered via a single-prong or a dual-prong cannula geometry. A temporally varying boundary condition was used to apply a realistic breathing cycle to the base of the trachea. The patient mouth was “closed” to specific percentages by modifying the cross sectional area of a plane in the patient mouth. The total amount of CO2 inhaled, which should be minimized, was collected as a measure of therapy effectiveness. The mass CO2 inhaled was calculated by subtracting the mass of CO2 present in the airway at the …

Hargreaves Test On Formalin Injected Mice: A Neuropathic Pain Model, Caleb Mast

Liberty University Research Week

Neuropathic pain is a chronic condition resulting from nervous system injury or disease, commonly associated with multiple sclerosis, spinal cord injury and diabetes. Current mouse models rely on invasive surgical techniques such as spinal nerve ligation (SNL) or chronic constriction injury (CCI), which require specialized training, increase variability, and reduced accessibility. Previous studies in rats have shown that formalin injections can induce a persistent pain state and spinal molecular changes comparable to those observed in surgical models. This study investigated whether a single subcutaneous injection of 5% formalin is sufficient to produce neuropathic pain behaviors and nervous tissue changes CCI …

Histological Assessment Of Neuropathic Pain In Murine Nervous Tissue, Katelynn Castagnola

Liberty University Research Week

Neuropathic pain is a symptom of diabetes, multiple sclerosis, and HIV/AIDS that is difficult to treat since the pain originates in the central nervous system. Current models of neuropathic pain involve mice and are difficult to use, since the methods are invasive and require extensive training; ligation of the sciatic nerve or the T4 and T5 spinal nerves are the most common procedures today. However, it has recently been suggested that formalin can potentially induce chronic pain in mice, as it has been successfully induced in rats. Therefore, our experimental goal was to establish a formalin-induced model of neuropathic pain …

Beyond Labeling: Examining Mpox As A Sexually Transmitted Infection- ¿A Literature Review¿, Rachel Williams, Ashlan Killeen, Eunice Onwuka

Liberty University Research Week

Introduction

Since 2022, Mpox outbreak trends have marked a shift in the epidemiology of the disease which has long been treated as a zoonotic infection. This is due to emerging patterns of cases of Mpox linked with sexual transmission, particularly in non-endemic regions reporting over 100,000 cases across 122 countries. This pattern has raised growing concerns regarding sexual transmission of Mpox necessitating further investigation.

Aim/Objective

This literature review examines current epidemiological, clinical/virological evidence to evaluate Mpox as an STI beyond labelling. and provides foundational context for a forthcoming systematic review examining priority populations affected during the 2022–2025 global outbreak.

Proposed …

Active Barrier Cream Against Poison Ivy (Urushiol), Amanda Witherell, Annalee Gardner, Luthien Jones

Liberty University Research Week

Urushiol is an immunotoxic compound composed of a 3-substituted catechol and an alkyl side chain that contains 0-3 degrees of unsaturation. It is the substance in poison ivy that causes a negative response when it contacts skin. Commercial barrier creams currently exist that claim to protect the skin against urushiol but only serve to form a barrier between the oil and skin. This project aims to create a barrier cream that both forms a physical layer to protect the skin and neutralizes the urushiol as it sits on the cream. To neutralize the urushiol, it is proposed that either the …