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Evaluation Of Alternative Solvents For Electrospinning Occluded Scaffolds To Model Intracranial Atherosclerotic Disease In Blood Vessel Mimics, Olivia D. Rankin

Master's Theses

Intracranial atherosclerotic disease (ICAD) is characterized by a buildup of fatty plaque within the walls of arteries supplying the brain, resulting in vessel narrowing, restricted blood flow, and increased risk of ischemic stroke. While various treatments exist for ICAD, most are accompanied by high recurrent stroke rates and other adverse events, highlighting the need for further investigation and models for pre-clinical testing. Tissue engineered Blood Vessel Mimics (BVMs), consisting of a polymer scaffold sodded with human vascular cells, serve as physiologically relevant in vitro models for vascular device testing. This thesis focused on the application of alternative solvents to a …

Salary Report, June 2026, Eastern Michigan University

EMU Salary Reports

No abstract provided.

Increasing Lead (Pb) Screening Participation Rates In The Pediatric Patient Population At The Philadelphia College Of Osteopathic Medicine Lancaster Avenue Community Healthcare Center, Jacob Varrato

PCOM Biomedical Studies Student Scholarship

Elevated blood lead levels (EBLLs) are an ongoing public health crisis predominantly affecting children under six in low-income communities located in major cities across the United States (Zartarian et al. 2024). Chronic lead exposure due to outdated housing, polluted water, and contaminated soil is especially harmful in early childhood. Frequent hand to mouth contact at this age increases the risk of ingesting particulate matter containing lead (CDC). EBLLs can predispose children to neurocognitive deficits, cardiovascular disease, and epigenetic modifications to gene expression patterns (Collin et al. 2022). While precautionary measures and timely screening protocols greatly reduce the risk of developing …

Effects Of Mitoquinone On Doxorubicin-Induced Cytotoxicity In H9c2 Cardiac Myoblasts And 22rv1 Prostate Cancer Cells, Tia Patrick

PCOM Biomedical Studies Student Scholarship

Introduction:

Although Doxorubicin (DOX) is a widely prescribed chemotherapeutic agent, its clinical use is limited by cardiotoxicity (DIC) caused by oxidative stress, mitochondrial dysfunction, and cardiac apoptosis. Dexrazoxane (DEX) is the only FDA-approved cardioprotective agent to prevent DIC. However, DEX may induce secondary malignancy. Mitochondria-targeted antioxidants (MTAs), such as mitoquinone (MitoQ) and 10-(6′-plastoquinonyl) decyltriphenylphosphonium (SKQ1), selectively accumulate within mitochondria to scavenge reactive oxygen species (ROS) at their primary site of production. Our previous findings demonstrated that MitoQ and SKQ1 prevented the reduction in cell viability caused by DOX treatment in H9c2 myoblasts. However, it remains unclear whether MitoQ can selectively …

Addressing Homelessness And Hunger Through A Human Rights Approach Focused On Collective Responses, R. Denisse Córdova Montes, Tamar Ezer

Georgia State University Law Review

The United States is experiencing unprecedented levels of homelessness and food insecurity. In 2024, the number of unhoused persons on a single night reached the highest ever recorded, and in 2023, 13.5% of the population lived in food insecure households, including 7.2 million children. Both homelessness and food insecurity disproportionately impact individuals based on race and gender.

In this context, community-led tools, such as community kitchen events and public feedings, have played an important role in providing those experiencing extreme hardship with access to adequate food and safe community spaces.

However, rather than supporting these efforts or addressing the root …

Note From The Chief Articles & Symposium Editor, Simyllina S. Chen

University of the Pacific Law Review

No abstract provided.

Adjunctive Psychosocial Interventions And Opioid Abstinence Among Patients Receiving Buprenorphine: A Randomized Clinical Trial., Michelle R. Lent, Emily E Hurstak, Kevin G Lynch, Emily Loscalzo, Kimberly Mazur, Helen L Lugo, Karen L Dugosh

PCOM Scholarly Works

IMPORTANCE: Adjunctive psychosocial treatments are recommended for many using medications for opioid use disorder (MOUD), but it is unclear which approaches can best enhance treatment outcomes.

OBJECTIVES: To evaluate the comparative effectiveness of 2 psychosocial treatments, peer recovery support (PRS) and cognitive-behavioral therapy (CBT), on opioid abstinence when used as adjunctive therapies to office-based buprenorphine treatment in adults with opioid use disorder (OUD).

DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial included US adults diagnosed with OUD referred for care at 5 federally qualified health centers with office-based addiction treatment programs by their clinicians from 2020 to 2024. Participants were …

The Spiritual Communities Of Bronies, Amie Sexton

Theses, Dissertations and Culminating Projects

Bronies, adult, typically male, fans of the cartoon My Little Pony: Friendship is Magic, have long been regarded for seemingly breaking expectations around gender norms. This study finds that Bronies break expectations around what is expected of spiritualism. Through interviews and ethnographic observation of social media spaces Bronies frequent, it is found that spirituality based on the cartoon within the fandom is broad, diverse, and at times, normative. A proportionally-small group of fully sincere spiritualists with plural experiences and strong convictions inspire a much larger community of post-ironic aspirants. Aspirations towards spiritual experiences and the development of profound terminologies create …

The Impact Of Multi-Brand Promotions On Visual Distinctiveness And Consumer Choice, Melanie Isabel Paul Austin

Dissertations, Theses, and Capstone Projects

In cluttered retail environments, marketers must often decide whether to showcase a brand alone in a single-brand promotion, or alongside other brands in a multi-brand promotion. Prior research has explored the role that different retail promotions play in consumers’ choice contexts. This research explores how multi-brand promotion versus single-brand promotions impact consumers’ purchase behavior. Study 1 uses secondary scanner data to show that multi-brand promotions lead to significantly higher sales of the promoted product compared to single-brand promotions. Study 2 replicates our secondary data findings in a quasi-field study with actual choice behavior. A series of lab studies again confirm …

An Inferential Analysis Of Lexical Networks, Christopher D. Gravelle

Dissertations, Theses, and Capstone Projects

Lexical networks are graphs where words are treated as nodes, and relations between words are treated as edges. The adoption of lexical networks in psycholinguistics is impeded by a lack of readily available inferential methods, which limits work to purely descriptive analyses with little ability to make inferences about what variables account for lexical network structure. The current research explores the use of latent space network models as a method for analyzing lexical networks. Latent space network models are latent variable regression models, which model the presence or strength of edges by estimating pairwise distances between nodes in a latent …

Goddess In A Trash Can: Religious Ritual Disposal In New York City Public Parks, Zoe Oro-Hahn

Dissertations, Theses, and Capstone Projects

Practitioners of Afro-Caribbean religions, including Santería, Vodou, Espiritismo, and Las 21 Divisiones, utilize the New York City Public Parks system to hold rituals, connect with spirits and ancestors, and dispose of religious remains leftover from trabajos (workings) and brujería (witchcraft). Utilizing photos from Van Cortlandt Park in the Bronx, my thesis considers the religious, political, social, and practical rationale behind this phenomenon, explores the rituals occurring, and provides policy suggestions that balance religious needs of practitioners with the safety and wellbeing of New York City’s parks.

Radiotheranostics For Gynecological Pathologies, Joni Sebastiano

Dissertations, Theses, and Capstone Projects

Molecular imaging, specifically positron emission tomography (PET), is vital for detecting disease and understanding its biological makeup. The exploitation of radiolabeled antibodies for PET imaging has proven to be indispensable to the field of molecular imaging over the last several decades. The development of radioimmunoconjugates for use in immunoPET has not only allowed for the sensitive, specific, and high-resolution detection of disease, but has also enabled a deeper understanding of the disease biology, ultimately guiding more personalized therapeutic strategies. Most typically, this technology is harnessed for the diagnosis and treatment of cancer, however more recently, the field has explored the …

The Hope Dionysos (After Augustus): A Post-Actian Reading Of Dionysian Imagery, Jane Horman

Dissertations, Theses, and Capstone Projects

At the center of the Roman court at The Metropolitan Museum of Art in New York stands an almost seven-foot-tall statue of an androgynous looking figure, leaning on a smaller statue of a woman. This piece, formally known as Statue of Dionysos Leaning on a Female Figure, has been nicknamed the Hope Dionysos for both the archaic statue he is leaning on, as well as the family to whose collection he belonged for many years. However, in its day, the statue occupied a complicated place in Roman culture. This paper will examine the ways in which Dionysos, specifically through …

Trans-Cyber Cinema: Digital Embodiment In Science-Fiction Films, Sophia R. Schrock

Dissertations, Theses, and Capstone Projects

This thesis aims to define the trans-cyber genre within cinema. By looking retroactively at a selection of nine films made across various decades and countries, this genre connects these films through their visualization and thematization of both trans and cyber embodiments, whereby the trans-cyber being emerges. Before the cinematic analysis and explanation of the three generic conventions selected for this thesis – transformation of body/gender; altered reality, memory, and temporality; and, radical death – the two intertwining theoretical frameworks will be established. This includes a brief summary of applicable transgender theory, and an introduction to cyborg theory (using Donna Haraway’s …

A Hot Topic:
Congressional Polarization And Climate Change, Mercedes R.P. Wilby

Dissertations, Theses, and Capstone Projects

Scholars offer competing explanations for how congressional polarization develops and operates. The literature variously points to shifting agendas, procedural change, or member adaptation or replacement. In this project, I study how congressional polarization occurs by asking what mechanisms account for the emergence of climate policy polarization. Climate policy is a useful test case to evaluate these competing theories. As a relatively low-salience, highly technical issue that is neither new nor inherently ideological, it is not an obvious candidate for deep partisan division. Yet climate policy has become sharply polarized, extending partisan disagreement even to the underlying science.

In order to …

Twitteratura: Digital Social Reading And Active Reception Of Literary Texts In The Context Of Italian Contemporary Literature, Iuri Moscardi

Dissertations, Theses, and Capstone Projects

This dissertation explores Digital Social Reading (DSR) as a novel mode of literary engagement, focusing on the Italian project Twitteratura, a series of social reading experiments conducted on Twitter (2012–2016) and later on the Betwyll app. The research situates Twitteratura within the intersection of Reader-Response Theory, Digital Humanities, Reception Studies, and Sociology of Literature, demonstrating how digital environments reshape the act of reading and interpretation. Through detailed analyses of four DSR projects centered on major twentieth-century Italian authors—Cesare Pavese, Pier Paolo Pasolini, Italo Calvino, and Natalia Ginzburg—this dissertation argues that Twitteratura provides a concrete, data-rich demonstration of Wolfgang Iser’s reader-response …

No Reply: The Exclusus Amator Through Ancient And Modern Love Poetry, Ayla Wing

Dissertations, Theses, and Capstone Projects

This thesis examines the exclusus amator, or “shut-out lover” trope as it appears in Greek and Roman texts, surveying the many examples of this motif and picking out its main elements: Intense Pain, Strong Emotions, Rejection, Interaction with the Door. It also notes the universality of the trope (anyone of any sexuality from any walk of life can be an exclusus amator) and the many references to the motif in other types of ancient media, including in graffiti, which shows that the exclusus amator was a real-life occurrence. This paper then examines modern songwriting, a genre chosen for its similarities …

The Soviet New Wave: A Comparative Analysis, Katarina Parks

Dissertations, Theses, and Capstone Projects

This thesis aims to assert the Soviet New Wave into the global New Wave cinema movements of the late 1950s and 1960s. Focusing on three Soviet films—Marlen Khutsiev's I Am Twenty (1965) and July Rain (1967), and Georgiy Daneliya's I Walk the Streets of Moscow (1964)—this study proposes that these works fully commit to the New Wave expression in form, sensibility, and content, despite the aggressive censorship of Soviet authority. By comparing the Soviet films with the French Nouvelle Vague, as well as with British, Polish, and Czechoslovakian New Wave cinemas, the thesis identifies recurring motifs: the centering of young …

Gremlin Theory: A Film Art Of Joe Dante, Frank Falisi

Dissertations, Theses, and Capstone Projects

This thesis seeks to establish the work of the filmmaker Joe Dante as a catalyzing and anarchic force let loose inside larger, dumber superstructures: linear narrativity, Hollywood, America, etc. It works to read the genre films he worked on—many of them made as popular entertainment for mainstream movie studios—as moments of actual subversion, allocating status quo (studio system) resources to create a biting-back against American imperial norms in the lingua franca of Marx and the Marx Brothers: gummy leisure-seeking stupidity and Gremlin transformation. This thesis seeks to argue that to understand Dante’s work is to understand pop transfiguration itself. This …

The Other Sodomites: A History Of Racial Queerness, Paris Shih

Dissertations, Theses, and Capstone Projects

The Other Sodomites traces the "racial logic of sodomy" from the medieval to modern periods. Reading across a wide range of literary and cultural texts, including medieval tales, theological treatises, travel narratives, stage plays, topographical poems, and prose fiction, the current study explores the structural relationship between discourses of sodomy and pivotal moments of racialization in western history, from the Judaization of sodomy in the Middle Ages, through its Islamization and Catholicization during the global Renaissance, to the continentalization and orientalization of sodomy in the nineteenth century. Despite the shifting zones of sodomitic significance, there existed a persistent racial logic. …

Theatrical Agency In The Constitution Of Logical Space, Esther Marveta Neff

Dissertations, Theses, and Capstone Projects

This dissertation takes advantage of our current moment of collapse and shifting episteme to move from resistance and critique into modes of position, prefiguration, and praxiocentricism, giving not only a critique of the colonial-modern logical space of Theatrum Mundi, but also aiming to configure the thetic consciousness that grounds “theatrical agency” in the logic of cognitive and social epistemological modelling.  In what ways do we “build our own worlds”? What does “theatricality” tell us about human agency, especially in the domain of “theoretical attitudes,” and “consciousness”? In what ways, and to what extent, are we responsible for constituting …

Immunomodulatory And Signaling Molecules From Plant-Associated Bacteria: Toll-Like Receptor 4 Agonist Adjuvants And Diketopiperazine-Mediated Communication, Marian Romaine

Dissertations, Theses, and Capstone Projects

Medicinal plants and their associated microbiomes constitute a rich source of bioactive natural products with applications in immunotherapy and microbial ecology. Herbal formulations have long been valued for safe immune enhancement, while bacterial signaling molecules govern community behaviors critical to pathogenesis, symbiosis, and environmental processes. Bacterial lipopolysaccharides (LPS) from plant-associated Gram-negative bacteria have emerged as potent TLR4 agonists, yet their endotoxic potential limits direct use, and diketopiperazines (DKPs) serve as versatile quorum-sensing mediators capable of modulating biofilms in mixed microbial systems.

The work in this thesis comprises two independent but complementary research strands. The first strand pursued the engineering of …

Three Degrees Of Representation: How Genai Filters, Retrieves, And Remixes Lesbian Film Data, Maria G. Baker

Dissertations, Theses, and Capstone Projects

This project investigates how generative AI systems assemble, filter, and represent Lesbian film data. Through auditing GenAI outputs across multiple dimensions (text, images, metadata), 3°R explores what gets included, excluded, and transformed in the process.

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Three Degrees of Representation is a public website (https://mgb513.github.io/lesfilm-meets-AI/) featuring an investigation of AI-generated images and texts in response to Lesbian film data. Filtering simple prompts based on Lesbian film titles through the algorithms of AI image and text generators makes visible how these systems digest and remix existing (training) data, and how aspects of Lesbian representation are either amplified or suppressed …

Healing Historical-Intergenerational Trauma And Colonial Soul Wounds With Ancestral Healing Practices And Psychosocial Limpias: An Ofrenda For The Salvadoran Community, Joanna D. Beltrán Girón

Dissertations, Theses, and Capstone Projects

In 1992, the United States-backed Salvadoran military and the leftist guerrillas signed the Chapultepec Peace Accords, which put an end to a 12-year war in El Salvador that resulted in 75,000 deaths, 12,000 forced disappearances, and half a million internal displacements. Around 85% of the reports made by survivors of the war attributed the violence to state agents, paramilitary groups, and death squads.While taking into account this history of state violence, this dissertation is interested in the psychosocial aftermath of the war and in how survivors integrate healing practices in their lives in response to the painful memories their bodies …

Reexamining The Croton Aqueduct: A Ward-Level Microhistorical Analysis Of Infrastructure And Cholera Mortality In 1849 New York City, Alexandria R. Toothman

Dissertations, Theses, and Capstone Projects

This work reexamines the Croton Aqueduct’s role in public health by shifting analysis from the citywide level to the ward level, revealing that infrastructure expansion did not produce uniform benefits across New York City. When the Croton Aqueduct opened in 1842, it was celebrated as an achievement that would deliver pure water and eliminate disease. However, only seven years after its opening, in 1849, cholera returned with greater force in the Sixth Ward. This work shows that the uneven distribution of Croton infrastructure corresponded with uneven cholera mortality rates, challenging narratives that present Croton as a singular triumph of urban …

Clinical Presentations Of Pemphigus Vulgaris In Patients With Skin Of Color: A Systematic Literature Review, Haya Alkiswani, Simona Alomary, Jared Boetes, Nicole J. Baker, Susan C. Taylor

SKMC Student Presentations and Publications

Background: Pemphigus vulgaris (PV) is a rare, often severe autoimmune disease affecting skin and mucous membranes. Despite the scarce literature on PV in skin of color (SOC) populations (Fitzpatrick III-VI), existing studies suggest that there are misdiagnosis, delayed treatment, and recurrence of symptoms in SOC patients with PV. Objective: This review explores the clinical presentations of PV reported in patients with SOC, diagnostic challenges and delays, treatments, and patient outcomes to allow for an improved understanding of how PV manifests clinically in darker skin. Methods: A systematic literature review was conducted using articles found in PubMed and Embase. Two independent …

Toward A Synthetic Theory Of Tolerance For Carnivores: Learning From A Half-Century Of Research On Attitudes Toward Wolves, Jeremy T. Bruskotter, John A. Vucetich, Lisa Naughton-Treves, José Vicente López-Bao, Benjamin Ghasemi, Nicole D. Sintov, Tara L. Teel, Neil H. Carter, L. Mark Elbroch, Adrian Treves

Michigan Tech Publications

Human intolerance is a critical factor limiting both the distributions and populations of large carnivores. Using gray wolves as a case study, we synthesize a half-century of scholarship with the aims of clarifying the conceptual foundations of “tolerance” and integrating insights from across the social sciences. Specifically, we review longitudinal studies of attitudes toward wolves and show how trends vary across the populations examined. We then identify and discuss three complementary theories that help explain variation in tolerance across individuals, social groups, and societies: (1) Risk–benefit theories illuminate how perceptions of risks, benefits, and controllability shape individuals’ tolerance of carnivores; …

When A Mass Resignation Becomes A Merger: Rethinking Asset Acquisitions For The Ai Era, Nina Fridman

University of Chicago Law Review

The Microsoft–Inflection AI deal shocked Silicon Valley: Nearly all seventy of Inflection’s employees resigned simultaneously to join Microsoft, which then paid the startup’s shell $650 million. After the mass exodus, Inflection appointed new leadership that switched the company’s direction, while Microsoft assumed the mantle of Inflection’s old mission. The competitive effect was thus nearly identical to that of a traditional acquisition. But relying on their novel deal structure to shield them from regulatory requirements, Microsoft and Inflection barreled ahead without filing a notice of the transaction with regulators. The rest of the industry soon followed suit, with Amazon, Google, and …

The Dermatologic Effects Of Climate Change On Skin Of Color Populations: A Comprehensive Review, Grace Ugwueke, Simona A. Alomary, Nicole J. Baker, Susan C. Taylor Md, Nada Elbuluk Md

Student Papers, Posters & Projects

Background: Climate change contributes to rising temperatures, worsening air pollution, increasing UV exposure, and more frequent extreme weather events with downstream consequences for dermatologic conditions. However, limited research has examined how these climate-related effects can impact skin of color (SOC) populations, who often face disproportionate environmental exposures and structural inequities. Objective: To summarize the dermatologic implications of climate and environmental stressors on SOC populations. Methods: A literature search of PubMed and Embase (2000-2025) identified studies assessing dermatologic outcomes related to climate change or environmental exposures. Of 1254 records screened, 133 duplicates were removed, leaving 1121 studies for evaluation. Twenty-three studies …

The Administrative Law Of Mccarthyism, Nicholas Handler

Faculty Scholarship

This Article recovers the largely overlooked legal and administrative history of the federal loyalty-security program, and argues that it played a formative role in the development of modern civil service protections and administrative law. During the McCarthy era, the United States Civil Service Commission (CSC), under pressure from Congress, implemented a sweeping loyalty program aimed at rooting out purportedly disloyal federal employees. Though often remembered as a moment of political overreach and civil liberties violations, this Article shows that the loyalty program simultaneously catalyzed a surprising expansion in procedural rights for government workers—both through internal reforms initiated by the CSC …