Sex Differences And Cytokine Profiles In Rheumatoid Arthritis, Ella Margaret Bartley Miss

International Undergraduate Journal of Health Sciences

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by persistent inflammation, joint destruction, and notable differences in prevalence and severity between sexes. Elevated levels of pro-inflammatory cytokines, such as interleukin (IL)-1, IL-6, and tumour necrosis factor alpha (TNF-α), are well established mediators of RA pathology. Although extensive research has elucidated their pathological roles, the influence of sex on cytokine profiles and RA outcomes remains undefined.

This review examines preclinical and clinical studies analysing sex-specific cytokine responses in RA. Findings reveal that female patients and experimental models exhibit higher concentrations of pro-inflammatory mediators, with oestrogen and androgen signalling playing relevant …

Full Issue: The International Undergraduate Journal Of Health Sciences, Volume 6, Issue 1, July 2026

International Undergraduate Journal of Health Sciences

Full Issue: The International Undergraduate Journal of Health Sciences, Volume 6, Issue 1, July 2026.

The Impact Of Abortion Laws On The Rights Of Future Generations In Climate Change Litigation, Laura Chiu

Florida Journal of International Law

In their own respects, the United States of America, the Republic of Korea (Korea), and India are three vastly different countries, and their differences are also apparent within their respective legal systems and the legal protections, or lack of, in place on abortion. Throughout the years, these three countries have shifted in three distinct directions with their abortion laws. The United States has regressed in its protection of the right to an abortion. Korea has recently decriminalized abortion for the first time in 2021. And India has continued to pass increasingly progressive abortion laws and abortion rulings over the years …

Vabr-2.0: Variable-Adaptive Bio-Resonance Engine (Physical Prototype Edition) Date: 2026-07-29 Status: Open-Hardware • Builder-Grade • Test-Bench Ready, Michael Victor Caldwell Mr.

Defensive Publications Series

The VABR-2.0 is a physical, buildable Multi-Modal Biopotential Acquisition and Adaptive Feedback System. It stabilizes biological signal acquisition by actively suppressing noise, drift, and interference while ensuring strict adherence to biomedical safety standards (IEC 60601-1).

In engineering terms, "Variable-Adaptive Bio-Resonance" is implemented as a High-Impedance Analog Front End (AFE) with Active Common-Mode Rejection and FPGA-based Adaptive Filtering. It captures weak biosignals (EEG, ECG, EMG, EOG) with high fidelity, processes them in real-time to remove artifacts (motion, muscle noise, power line hum), and provides safe, isolated feedback (visual, auditory, or haptic) for neurofeedback or physiological monitoring research.

This document provides the …

Review Of Phytoplankton Community Structures And Their Environment In Ugandan Waters: A Case Of Murchison Bay And Napoleon Gulf, Northern Lake Victoria, Samiha M. Gharib, Ahmed M. Heneash, Mohamed A. Heneash

Blue Economy

Victoria Lake has seen a significant deterioration in water quality since the 1960s, facing serious ecological challenges due to physicochemical, and biological processes, as well as human activities in the surrounding watershed. The primary factor contributing to this decline is eutrophication, which has caused a shift in the dominant phytoplankton species from diatoms to nitrogen-fixing cyanobacteria. This shift has resulted in persistent algal blooms. This review centers on the Ugandan waters of Lake Victoria, specifically in Napoleon Gulf and Murchison Bay. It examines the composition of phytoplankton species, their numerical abundance, spatial distribution, and total biomass, as measured by chlorophyll …

Soybean Fermentation Broth Alleviates Indomethacin-Induced Gastric Mucosal Injury, Hsiao-Chi Wang, Yue-Jhu Chen, Hui-Yun Tsai, Jue-Liang Hsu, Yu-Kuo Chen

Journal of Food and Drug Analysis

Dietary strategies and plant-based fermented foods have attracted increasing interest for supporting gastrointestinal health, particularly under conditions of drug-induced mucosal stress. Soybean fermentation broth (SFB), a fermented soybean-derived product, may possess enhanced nutritional and functional properties through fermentation-associated generation of bioactive peptides and antioxidant metabolites. This study evaluated the gastroprotective effects of SFB in an indomethacin-induced gastric injury model in rats and investigated the underlying mechanisms. Indomethacin markedly induced gastric ulcer formation (16.61 ± 1.38 mm²), whereas SFB pretreatment significantly attenuated ulcer development in a dose-dependent manner, reducing ulcer area to 6.66 ± 0.98, 3.89 ± 0.63, and …

Gut Microbiota-Mediated Modulation Of Circadian Rhythms: Physiological And Molecular Impacts Of Dietary Composition And Feeding Time, Yen-Chun Koh, Chun-Che Chang, Min-Hsiung Pan

Journal of Food and Drug Analysis

Circadian rhythms regulate fundamental aspects of physiology and behavior. The disruption of circadian rhythms has been associated with metabolic disorders, cardiovascular disease, obesity, and impaired immune function. Feeding behavior and gut microbiota represent two essential nodes within this regulatory network, as both are highly responsive to environmental cues such as diet composition and sleep-wake cycles. Research has shown that high-fat diets, excessive fructose, and chronic alcohol consumption perturb peripheral circadian rhythms and impair metabolic pathways, contributing to obesity and insulin resistance. Conversely, dietary interventions such as time-restricted feeding and macronutrient-specific entrainment can restore rhythmic gene expression and prevent metabolic pathologies. …

Benefits And Risks Of Consuming Cannabis Sativa L. In Food, Ewa Matyjaszczyk, Maria Śmiechowska

Journal of Food and Drug Analysis

Cannabis sativa L. or hemp is a cosmopolitan, multi-purpose plant and area of its cultivation has been growing in recent years. Its public perception is influenced by potential to produce narcotic substances. However, hemp seed can be a valuable source of nutrients for humans and may be of particular interest in more sustainable food consumption patterns, including vegetarian and flexitarian diets.

The paper presents benefits and risks of hemp seeds in case of their consumption in food. Low cannabinoids varieties are considered only. The biological activity of cannabinoids and related effects are considered out of scope of the study.

Nutritional …

The Effects Of Jasmine And Champaca Aromatherapy Combined With Acupressure On Sleep Quality In Older Adults With Non-Communicable Diseases: A Quasi-Experimental Study In Rural Northern Thailand, Sriwan Chutithamniti, Katekaew Seangpraw, Prapaporn Tulwattanakul, Manuchet Manotham, Parichat Ong-Artborirak, Nestor Asiamah, Wannita Sakulwattana, Surangkana Chairinkam, Phatcharee Pimalram, Wichida Larsomsri

Journal of Health Research

Background: Poor sleep is common among older adults and negatively affects physical and mental health. This study evaluated the effects of jasmine and champaca essential oil aromatherapy combined with acupressure on sleep quality and cardiovascular parameters among older adults.

Methods: A quasi-experimental study was conducted in rural Phayao, Thailand. Older adults aged ≥60 years with non-communicable diseases and poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] > 5) were assigned to either an intervention group (n = 54), receiving aromatherapy and acupressure for 6 weeks, or a control group (n = 54), receiving usual care. Sleep quality, blood pressure (BP), and …

Icu Nurses Knowledge, Attitudes, And Involvement In Clinical Research In Australia–A National Survey, Joanne Mcintyre, Frances Fengzhi Lin, Anne Mette Nørby Adams

International Nursing Research Congress (INRC)

Introduction: Clinical research is vital in critical care settings to support evidence-based care for patients. Studies have shown that hospitals involved in research have better outcomes, but the quality of the study is dependent on the multi-disciplinary team involvement, often including the engagement of nurses in clinical research protocol development and delivery. A recent literature review highlighted variable levels of nurses’ clinical research engagement with the need for targeted education, improved communication, and institutional backing, to ensure nurses better engage. However, despite international recognition of the issue, little is known about how Australian ICU nurses engage with clinical research.

Aim: …

Climate Change And Desert Ecosystem Resilience: A Systematic Review Of Impacts, Adaptation Strategies, And Sustainability Pathways, Ghada Abd Elsattar Mohammed Oraby, Garmat Zahra

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Desert ecosystems are among the most climate-sensitive environments on Earth, where rising temperatures, altered precipitation regimes, and increasing aridity threaten ecosystem stability, biodiversity, and ecological functioning. Despite covering more than one-third of the global land surface, a comprehensive understanding of how climate change affects desert ecosystem resilience and the effectiveness of adaptation strategies remains limited. This study conducted a systematic review following the PRISMA framework to evaluate the impacts of climate change on desert ecosystem resilience and to identify effective adaptation and restoration pathways. A total of 16 high-quality studies were selected from 403 records retrieved from the Scopus database. …

Evaluation Of Tsunami Preparedness And Appraisal Of Disaster Mitigation Education In Kebumen Regency, Indonesia: An Application Of Marker-Based Augmented Reality Approach, Muhammad Guruh Bintang Wicaksana, Erni Suharini, Andi Irwan Benardi, Edi Kurniawan, Puji Lestari, Atta-Ur Rahman

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study addresses the critical gap in tsunami disaster mitigation education and the lack of interactive, contextually field-based disaster education media. It develops and evaluates a tsunami preparedness medium using a Marker-Based Augmented Reality (MBAR) approach, specifically tailored to the tsunami risk profile of Karangbolong Village, Kebumen Regency, Indonesia. Methodologically, the study integrates three frameworks: a disaster literacy model (knowledge, skills, attitudes), a disaster literacy continuum (basic to critical), and the UNESCO-IOC Tsunami Ready 12-indicator framework, combining them into a single instructional product developed through the Multimedia Development Life Cycle (MDLC). This integration of all three frameworks into one locally …

Microplastic Effect On Behavior Of Nudibranch (Berghia Stephanieae); A Trophic Transfer Study, Isabela Salina Fernandes Beneli

Electronic Theses and Dissertations 2020 - Present

With the continuous rise in economic supply and demand, an enormous increase in waste, litter, and pollution has been seen globally, with plastic pollution being the most abundant category. Microplastic (< 5 mm), derived from larger plastics, pollution is intensely widespread across marine ecosystems and can be transferred across trophic levels through predator-prey interactions. Recent studies have shown that ingestion of MPs can damage cells, tissues, and internal organs and increases oxidative stress leading to malformations, reduced feeding and growth, , and slower developmental rates in a wide array of organisms. This study examined the trophic transfer of microplastics (MPs) from the anemone Exaiptasia pallida to its specialist predator Berghia stephanieae, and evaluated the effects of exposure on predator behavior. A dose-response experiment demonstrated that MP retention in E. pallida decreased over time, although higher exposure concentrations resulted in greater initial microplastic concentrations. Trophic transfer to B. stephanieae was confirmed through feeding experiments. Behavioral assays revealed that B. stephanieae did not exhibit a preference between MP-exposed and control prey. However, microplastic …

The Study Of Hydrophobic Biomolecules With Matrix Assisted Laser Desorption Ionization Mass Spectrometry And Atomic Force Microscopy, Brandy L. Perkins

LSU Doctoral Dissertations

Abstract

Matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS) can be used to obtain localization and chemical information of hydrophobic biomolecules on tissue samples.  A technique has been developed to modify a standard MALDI matrix that improves the selectivity for hydrophobic biomolecules on the tissue sample. The modification involves the use of a Group of Uniform Materials Based on Organic Salts (GUMBOS). GUMBOS are ionic liquids (IL) that are bulky organic ions with a counter ion that can be changed for tuning.  They are more stable than traditional matrices under vacuum.  Unlike traditional IL’s, the GUMBOS melting point ranges …

Maleficia's Magic: Witchcraft, Race, And The Legacy Of Afro-Mexican Women And Identity In Colonial New Spain, Siobhan K. Arechavala

Honors Theses

This thesis examines the disproportionate prosecution of mulatta and Black women by the Mexican Inquisition in the sixteenth and seventeenth centuries and argues that this pattern was not incidental to Spanish colonialism but central to it. Drawing primarily on inquisitorial trial records from the Huntington Library’s Mexican Inquisition Papers and the Archivo General de la Nación’s Ramo Inquisición, alongside period treatises and secondary scholarship on witchcraft, caste, and Afro-Mexican history, the study traces how limpieza de sangre, Christian demonology, and colonial racial hierarchy combined to position African-descended women as embodiments of the disorder colonial elites feared most. The first chapter …

Uhsp Student Code Of Conduct 2026-2027

Handbooks

No abstract provided.

Dishwashers And Dicta: The Fifth Circuit's Not-So-Quiet Attack On Doe Authority In Louisiana V. United States Department Of Energy, Robert G. Torpey

Villanova Environmental Law Journal (1991 - )

No abstract provided.

Transformasi Konsumsi Anime Di Prancis Lewat Platform Streaming, Diajeng N. R. Salsabila, Airin Miranda

Multikultura

Covid-19 pandemic has brought significant changes to media consumption habits, especially on streaming platform services. The government's appeal for people to remain at home has ultimately contributed to a spike in the number of users of these services, with anime content as the top choice. This phenomenon is reminiscent of the early period when anime such as Goldorak and Candy Candy first dominated the French market, marking the beginning of a major shift in the acceptance of Japanese popular culture in France. To answer this research problem, Wahidmurni's (2017) qualitative method, Fairclough's (1995) critical discourse analysis, and literature study were …

Pemaknaan Ikon Makhluk Hidup Dengan Kaligrafi Arab Pada Srabad Dari Kesultanan Cirebon, Fitria Anisya, R. Cecep Permana

Multikultura

Islamic art in the Nusantara (Indonesian Archipelago) represents a fusion of Islamic tradition and local cultural wisdom that flourished through coastal trade routes. One of the most distinctive manifestations of this fusion is the art of srabad Cirebon. Etymologically, the term srabad derives from the Javanese expression "mingser saking abad", meaning the transition from the Hindu era to the Islamic era. This art form presents anthropomorphic elements uncommon in conventional Islamic artistic tradition, in which icons of living creatures are specifically constructed from the structure of Qur'anic verses. Studies that examine the relationship between the depiction of living creature icons …

Metafora Dengan Unsur Alam Dalam 5 Lirik Lagu Soundtrack Moana 2 Versi Belanda, Husna Nafisa, Triaswarin Sutanarihesti

Multikultura

Animated films convey stories through visuals, music, and song lyrics, all of which play an essential role in constructing meaning and evoking emotion. The Dutch-language soundtrack of Moana 2 employs nature-related metaphors to depict the characters' journeys, inner conflicts, and the relationship between humans and nature. This study aims to identify the types of metaphors, based on Rozemarijn van Leeuwen’s (2002) classification, found in the song lyrics “Terug,” “Verder Gaan,” “Wordt het nog beter dan dit?,” “Hoor ik daar een chee hoo?,” and “Ga Los,” which were obtained from the official Genius website. This study adopts a descriptive qualitative method. …

Penggunaan Onomatope Dalam Buku Cerita Anak Berbahasa Mandarin Dan Bahasa Indonesia: Analisis Kontrastif, Ruixi Zou, Usmi Usmi, Uti Aryanti

Multikultura

This article examines the comparison of onomatopoeia in Mandarin Chinese and Indonesian in children's literature. The study aims to identify, classify, and compare onomatopoeic forms found in the Mandarin children's story Bǎo Húlú De Mìmì (The Secret of the Magic Gourd) and the Indonesian children's story collection Sehari Satu Dongeng. This research employs a descriptive qualitative approach and a contrastive analysis method. The data were collected through close reading and note-taking techniques, and were analyzed using referential and comparative methods. The classification is based on the source of the represented sounds, namely human sounds, animal sounds, natural phenomena, and …

Reinforcing Media Governance In Indonesian Dynamic Cyber Space, Poppy Setiawaty Nurisnaeny, Hendra Kaprisma, Chrisna Yudhawinata, Sudirman Sudirman

International Review of Humanities Studies

Following the rapid change in technology development, the Indonesian mass media have undergone a digital transformation. This digital mass media and its users have evolved, assimilated, and integrated themselves to fit in the cyber world. This distinguishing feature distinguishes them from traditional mass media. The cyber environment's infinite international boundaries are both advantageous and disadvantageous, as it is difficult to govern digital activity outside Indonesia's jurisdiction. This unregulated environment became a breeding ground for cybercrime, making the digital space unsafe for individuals and threatening national security. In response to this issue, the Indonesian government has enacted various laws and policies, …

Radical Responsibility: Sartre And The Ecocentric Erosion Of Human Agency, Khodadad Azizi, Naupal Asnawi, Abby Gina Boang Manalu

International Review of Humanities Studies

Contemporary ecological crisis persists despite decades of environmental ethics discourse and rising public awareness, a discrepancy researchers have named the awareness-action gap. One influential corrective, running from Aldo Leopold’s land ethic through Arne Naess’s deep ecology, addresses anthropocentric domination by folding the human being back into the biotic community as one member among others. This article argues that such levelling, whatever its merits against domination, carries an underexamined cost: it erodes the very ground on which anyone can be held responsible for ecological destruction, since only a being capable of choice, not soil, water, or rock, can be asked to …

Abstracts Of The 71st Annual Conference Of The Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists (Maenpp)

Midsouth Entomologist

October 27 & 28, 2025

Exploring The Relations Between Sleep And Mental Health Through The Constructs Of Sleep Health, Psychological Well-Being, Depression, And Anxiety, Taylor G. Wandtke

Undergraduate Honors Theses

Sleep and Mental Health have a variety of definitions and underlying constructs, as well as questionnaires to measure them. This study analyzed sleep and mental health constructs using a variety of questionnaires to examine how they may influence one another, providing valuable insight into the utility of both newly developed and established measures. With an analysis sample of N = 27, this study assessed the reliability of the novel Sleep Health Item Bank (SHIB) across its 14 dimensions and its correlations among psychological well-being, depression, and anxiety scores. Psychological well-being (PWB) was assessed by Ryff’s (1995) 18-item scale, and depression …

Surveys For Rare Springsnails In Southeast Oregon, 2025 With A Focus On The Donner Und Blitzen Pebblesnail (Fluminicola Insolitus), Jesse Laney

Institute for Natural Resources Publications

The Donner und Blitzen pebblesnail (Fluminicola insolitus) is a critically imperiled (G1/S1) freshwater snail historically known from a single spring, Page Springs, in the Donner und Blitzen River drainage of Harney County, Oregon. The species was petitioned for listing under the U.S. Endangered Species Act in February 2024. On January 26, 2026, the U.S. Fish and Wildlife Service published a positive 90-day finding initiating species status review (USFWS 2026).

In August 2025, the Oregon Biodiversity Information Center (ORBIC) at Portland State University, in coordination with the Nevada Division of Natural Heritage (NDNH), the U.S. Fish and Wildlife Service (USFWS), and …

Onomatopoeia In The Digital Comic The Wormworld Saga (2010), Nur Kholidah, Julia Wulandari

International Review of Humanities Studies

This study examines the forms and meanings of onomatopoeia derived from concrete sounds in the digital comic The Wormworld Saga. The study aims to explore the use of onomatopoeia in The Wormworld Saga and to describe its forms and meanings using a descriptive qualitative method. This study analyzes the forms of onomatopoeia based on the categories proposed by Gross (1988) and analyzes their meanings based on the classification proposed by Körtvélyessy and Štekauer (2024). The results show that there are 54 onomatopoeia classified as concrete sounds. In terms of form, the most common onomatopoeia are non-word forms, accounting for 41 …

Mll3 And Mll4 Sustain Hematopoietic Stem Cell Multipotency By Opposing A B-Cell Default State, Helen C Wang, Ran Chen, Wei Yang, Rohini Muthukumar, Tingting Hu, Riddhi M Patel, Emily B Casey, Elisabeth Denby, Run Zhang, Guojia Xie, Kai Ge, Grant A Challen, Jeffrey J Bednarski, Jeffrey A Magee

2020-Current year OA Pubs

Hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) are sustained by networks of transcription factors and epigenetic regulators that prime lineage-specific programs yet maintain multipotency. Two epigenetic regulators, MLL3 and MLL4, play important but distinct roles in maintaining this balance. MLL3 promotes HSC differentiation, whereas MLL4 opposes differentiation. These activities are essential for both normal homeostasis and leukemia suppression, yet it is not clear how MLL3 and MLL4 regulate HSC and MPP gene expression to control HSC/MPP fate decisions. To resolve these mechanisms, we performed an extensive series of single-cell genomic studies after conditionally deleting Mll3, Mll4 or both genes …

Loss Of Pleasure (Anhedonia): A Sex-Dependent, Cross-Species Consequence Of Unpredictable Signals To The Perinatal Brain, Anna M. Zhou, Madison R. Tetzlaff, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Tallie Z. Baram, Elysia Poggi Davis

Psychology Faculty Articles and Research

Reward seeking is an essential component of human behavior. Anhedonia (reduced motivation for and pleasure in reward) is a core feature of several mental illnesses. Early life adversity associates with later impairments in reward behaviors and related psychopathology; however, specific aspects of early adversity that lead to disrupted reward behaviors are unknown. Capitalizing on evidence that unpredictable signals to the developing brain constitute adversity and influence neurodevelopment, we examined whether exposure to perinatal unpredictable maternal signals associated with diminished reward responsivity, and probed causality using experiments in mice. We analyzed a longitudinal human study (N=158 mother/child dyads) and a …

What Does Sentience Mean At The Neural Level?, Björn Brembs

Animal Sentience

Jonathan Birch's (2025) LSE criteria for sentience include motivational trade-offs, exemplified by C. elegansweighing hunger against desiccation risk. Yet once the neural circuit is known, this "trade-off" reduces to a single inhibitory synapse—an ‘elemental’ account discrediting the ‘molar’ one. My commentary illustrates the same discrepancy in Drosophila: dopaminergic ramping during courtship as it progressively suppresses threat-detecting neurons; so persistence past danger reflects recalibrated valuation rather than a weighed decision. As neurobiology increasingly discovers such discrepancies, all criteria resting on behavioral classifications risk being defined away without altering the behavior's validity.